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neuropsychological basis of pattern vision in macaque monkeys.the central mechanisms of underlying pattern vision in macaques (rhesus and japanese monkeys) were investigated behaviorally and electrophysiologically. a series of studies indicated that there are two major processes underlying pattern vision. one of two processes is the process of attending selectively to pattern cues at background, with which inferior parietal cortex is concerned predominantly. the other is the process of pattern perception and cognition, in which inferotemporal cortex is inv ...19854024462
monocyte thromboplastin (tissue factor): complementary effect of lymphocytes upon its generation by endotoxin-stimulated monkey (macaca fuscata) cells.monkey (macaca fuscata) mononuclear leukocytes were stimulated to produce thromboplastin (tissue factor) upon exposure to lipopolysaccharide, lps. the stimulation was dose-related in the concentration range of 10(-5) to 10(-1) micrograms/ml of lps. lipid a portion of the lps molecule was essential to induce the leukocyte ability for tissue factor generation. thus, a lipid-lipid interaction between lps and the cells is a plausible trigger for eliciting the ability. approximately 50% of the tissue ...19854030740
two distinct projection areas from tongue nerves in the frontal operculum of macaque monkeys as revealed with evoked potential mapping.projection areas in the cerebral cortex from tongue nerves were investigated in anesthetized macaque monkeys (macaca fuscata). three tongue nerves (lingual nerve, chorda tympani, and a lingual branch of the glossopharyngeal nerve) were electrically stimulated and thereby evoked mass field potentials were recorded with microelectrodes roving through the exposed and buried frontal operculum. two distinct tongue nerve projection areas were thus located; one in the lower part of the precentral gyrus ...19854047521
retroperitoneal fibromatosis and acquired immunodeficiency syndrome in macaques: epidemiologic studies.at the university of washington regional primate research center, a simian acquired immunodeficiency syndrome (saids) associated with retroperitoneal fibromatosis (rf) has been observed in 82 macaques since 1976, including 77 pigtailed macaques (macaca nemestrina), two long-tailed macaques (m. fascicularis), one japanese macaque (m. fuscata) and two rhesus macaques (m. mulatta). the syndrome is characterized by immunodeficiency accompanied by a fibroproliferative lesion, primarily affects young ...19854057939
effects of chlordiazepoxide upon successive red-green discrimination responses in japanese monkeys, macaca fuscata. 19734196360
effects of chlordiazepoxide upon successive red-green discrimination responses in japanese monkeys, macaca fuscata. 19734196360
immunogenicity of purified, inactivated chikungunya virus in monkeys.chikungunya (chik) virus, harvested from infected bhk-21 cell cultures and highly purified by a method combining zinc acetate precipitation, sephadex-sepharose column chromatography, and sucrose density gradient centrifugation, was subjected to ultraviolet (uv) irradiation and treatment with formalin. inactivation of the virus by uv light was apparently a first-order reaction. the virus treated with 0.05% formalin at 4 degrees c was inactivated completely after 7 weeks, but when treated with 0.0 ...19734204490
immunogenicity of purified, inactivated chikungunya virus in monkeys.chikungunya (chik) virus, harvested from infected bhk-21 cell cultures and highly purified by a method combining zinc acetate precipitation, sephadex-sepharose column chromatography, and sucrose density gradient centrifugation, was subjected to ultraviolet (uv) irradiation and treatment with formalin. inactivation of the virus by uv light was apparently a first-order reaction. the virus treated with 0.05% formalin at 4 degrees c was inactivated completely after 7 weeks, but when treated with 0.0 ...19734204490
the primary structures of alpha and beta chains of adult hemoglobin of the japanese monkey (macata fuscata fuscata). biochemical studies on hemoglobins and myoglobins. xi. 19734205759
proceedings: 122. comparison of thermoregulatory responses in the japanese monkey(macaca fuscata) and the crab-eating monkey (macaca irus) during cold exposure. 19734207556
measurement of posture in japanese monkey (macaca fuscata) by telemetry. 19744209505
breeding of the japanese monkey on an island as a laboratory animal. 19734213763
clinical examinations on the japanese monkey (macaca fuscata). 19734213955
the present situation of japanese monkeys in their natural habitat. 19734214264
the present situation of japanese monkeys in their natural habitat. 19734214264
proceedings: plasma levels of luteinizing hormone during menstrual cycle and their response to gonadectomy in japanese monkeys. 19744219622
proceedings: plasma levels of luteinizing hormone during menstrual cycle and their response to gonadectomy in japanese monkeys. 19744219622
[an evaluation of affective value for vocal sign in macaca fuscata by skin potential reflex]. 19744366308
seasonal variation in urinary 17-oxosteroids and seminal fructose in male japanese macaque monkeys (macaca fuscata fuscata). 19744406683
male-malemounting in japanese monkeys (macaca fuscata). 19744462407
male-malemounting in japanese monkeys (macaca fuscata). 19744462407
plasma testosterone and male dominance in a japanese macaque (macaca fuscata) troop compared with repeated measures of testosterone in laboratory males. 19744474138
male dominance and aggression in japanese macaque reproduction. 19744475646
[a study of the marinesco body in monkey (macaca fuscata)--a comparative study to the marinesco body in man (author's transl)]. 19744480386
surface area in the japanese monkey, macaca fuscata. 19724621973
reproduction of japanese monkeys. 19724627307
reproduction of japanese monkeys. 19724627307
[amino acid sequences in the tryptic peptides from the alpha chain of japanese monkey hemoglobin]. 19724630698
amino acid compositions and n-terminal amino acid of all the tryptic peptides from the and polypeptide chains of adult hemoglobin of the japanese monkey (macaca fuscata fuscata). biochemical studies on hemoglobins and myoglobins. ix. 19724630784
histological and histochemical investigations on the stomach of man, japanese monkey (macaca fuscata yakui) and other animals. v. on the stomach of the pangolin (manis pentadactyla linne). 19734740712
research on dengue in tissue culture. vi. cultivation of dengue virus, type 4, in cultures of a japanese monkey kidney cell line. 19734802580
responsiveness to objects in free-ranging japanese monkeys. 19664955108
responsiveness to objects in free-ranging japanese monkeys. 19664955108
[changes of social behaviors following bilateral removal of the posterior parts of superior temporal gyri in japanese monkeys]. 19654957261
[changes of social behaviors following bilateral removal of the posterior parts of superior temporal gyri in japanese monkeys]. 19654957261
the lateral cervical nucleus of the japanese monkey (macaca fuscata). 19674962188
histological and histochemical investigations on the stomachs in man, japanese monkey (macaca fuscata yakui) and some other kinds of animals. i. cell-divisions in the gastric glands in man, japanese monkey and dog. 19674964925
histological and histochemical investigations on the stomachs in man, japanese monkey (macaca fuscata yakui) and some other kinds of animals. ii. what is the mucous neck cell? 19674964926
histological and histochemical investigations on the stomach in man, japanese monkey (macaca fuscata yakui) and some other kinds of animals. 3. the so-called immature chief cell. 19674964927
histological observations of eyelids of the japanese monkey and the rhesus monkey (histological studies of primates 1). 19674965750
[histological studies on the mucous membrane of the tongue of the japanese monkey (histological studies of the primates 4)]. 19674970788
electron microscopic studies on pigment granules in the substantia nigra and locus coeruleus of the japanese monkey (macaca fuscata yakui). 19684972310
aggression as studied in troops of japanese monkeys. 19674972333
aggression as studied in troops of japanese monkeys. 19674972333
histological and histochemical investigations on the stomach in man, the japanese monkey (macaca fuscata yakui) and other animals. iv. a new secretion type in the parietal cell. 19684975437
social organization of a troop of japanese monkeys in a two-acre enclosure. 19694976202
social organization of a troop of japanese monkeys in a two-acre enclosure. 19694976202
isolation of all tryptic peptides from the aminoethylated beta polypeptide chain of adult hemoglobin from japanese monkey (macaca fuscata fuscata) and their amino acid compositions. 19694981728
isolation of all soluble tryptic peptides from the alpha polypeptide chain of adult hemoglobin from japanese monkey (macaca fuscata fuscata) and their amino acid compositions. 19694981729
the n-terminal structure of adult hemoglobin from japanese monkey (macaca fuscata fuscata) and the n-terminal amino acids of all the tryptic peptides from its alpha and beta polypeptide chains. 19694981730
the effects of acute crowding on aggressive behavior of japanese monkeys. 19714999798
the effects of acute crowding on aggressive behavior of japanese monkeys. 19714999798
thermal and metabolic responses in the japanese monkey at temperatures of 5-38 degrees c. 19715000068
the primary structure of the beta-polypeptide chain of adult hemoglobin of the japanese monkey (macaca fuscata fuscata). 19715000512
synergistic interaction of corticotropin releasing factor and arginine vasopressin on adrenocorticotropin and cortisol secretion in macaca fuscata.plasma immunoreactive crf measured by radioimmunoassay decreased rapidly after intravenous injection of synthetic ovine corticotropin releasing factor (crf) and showed a bi-exponential decay curve in five macaca fuscatas. half lives of plasma immunoreactive crf were 5.8 +/- 1.4 (mean +/- sem) min for the fast component and 38.3 +/- 2.4 min for the slow component. a bolus injection of 5 micrograms/kg crf significantly increased the plasma cortisol level. crf at 5 micrograms/kg induced a delayed r ...19846087620
fine structure of human- and monkey-derived type c virus particles in monkey lymphoid cell lines expressing adult t-cell leukemia-associated antigens. brief report.ultrastructures of japanese monkey (macaca fuscata)-derived type c virus particles in a monkey lymphoid cell line, expressing adult t-cell leukemia (atl)-associated antigens, are indistinguishable from those of human atl-associated virus in human and monkey cell lines.19846089707
purification and characterization of a calcium-activated neutral protease from monkey brain and its action on neuropeptides.a calcium-activated neutral protease was purified from japanese monkey brain by ammonium sulfate fractionation and sequential column chromatographies monitored by assay of caseinolytic activity. the purified enzyme gave a single protein band on non-denaturing polyacrylamide gel electrophoresis, and consisted of two subunits with molecular weights of 74,000 and 20,000 as determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. the enzyme required millimolar order calcium ions for ...19846094523
seroepidemiological survey on dengue and japanese encephalitis virus infections in asian monkeys.to investigate the ecology of dengue and japanese encephalitis (je) viruses in the forest in asia, a seroepidemiological survey was carried out on 358 southeast asian cynomolgus (macaca iris), 33 indian bonnet (macaca radiata) and 37 japanese (macaca fuscata) monkey sera by a plaque reduction neutralization test. the results indicated that southeast asian monkeys were naturally infected with these viruses but the frequency of antibody to them varied considerably according to the geographical ori ...19846095461
human adult t-cell leukaemia virus is distinct from a similar isolate of japanese monkeys.we have compared the structural polypeptides of an adult t-cell leukaemia (atl) virus (atlv) isolate from a japanese patient with atl with those of a similar virus derived from a japanese macaque monkey. both are distinct but related entities. their core polypeptides p19 could not be distinguished, but p24, another core polypeptide, and their envelope glycopolypeptides differ. the human virus directs the synthesis of a single intracellular glycopolypeptide, gp68, while the macaque virus specifie ...19846096497
human adult t-cell leukaemia virus is distinct from a similar isolate of japanese monkeys.we have compared the structural polypeptides of an adult t-cell leukaemia (atl) virus (atlv) isolate from a japanese patient with atl with those of a similar virus derived from a japanese macaque monkey. both are distinct but related entities. their core polypeptides p19 could not be distinguished, but p24, another core polypeptide, and their envelope glycopolypeptides differ. the human virus directs the synthesis of a single intracellular glycopolypeptide, gp68, while the macaque virus specifie ...19846096497
nerve fibers in trabecular meshwork surface.the trabecular meshwork surface in the japanese monkey eye was observed by scanning electron microscopy. many varicose nerve fibers were recognized in the anterior surface of the trabecular sheets and in the intertrabecular space facing the anterior chamber. the nerve fibers often branched and thus formed a loose-meshed plexus. these varicose nerve fibers were identified by ultrastructural studies after the pretreatment of one animal with 5-hydroxydopamine as an adrenergic agent. most nerve fibe ...19846098756
bronchial response to methacholine and histamine in monkeys with beta adrenergic blockade.the possibility has been investigated that propranolol administration could alter bronchial reactivity to methacholine and histamine in monkeys (macaca fuscata and macaca fascicularis). the impedance of the total respiratory system was measured by the forced 3-hz oscillation method through an endotracheal tube. methacholine and histamine dose-dependently increased the impedance in monkeys irrespective of the route of administration (inhalation of aerosol or intravenous injection). propranolol tr ...19806103013
natural adult t-cell leukemia virus infection in japanese monkeys. 19826125790
natural adult t-cell leukemia virus infection in japanese monkeys. 19826125790
horizontal transmission of adult t-cell leukaemia virus from male to female japanese monkey. 19836130271
transmission of japanese monkey type c virus to human lymphocytes. 19836135012
inhibitory effects of histamine antagonists on the skin reaction with house dust allergen, histamine and compound 48/80 in japanese monkeys.using the skin of monkeys, we studied the participation of histamine receptors in the immediate skin reaction. intradermal injection of h2 agonist produced whealing reaction to a significant degree, although this effect was not so remarkable as the effect of h1 agonist. a non-thiourea h2 antagonist showed a significant inhibitory effect on the whealing reaction to allergen, compound 48/80, and histamine. these results suggest that h2 antagonist prevented the whealing reaction by changing the vas ...19836138882
inhibitory effects of histamine antagonists on the skin reaction with house dust allergen, histamine and compound 48/80 in japanese monkeys.using the skin of monkeys, we studied the participation of histamine receptors in the immediate skin reaction. intradermal injection of h2 agonist produced whealing reaction to a significant degree, although this effect was not so remarkable as the effect of h1 agonist. a non-thiourea h2 antagonist showed a significant inhibitory effect on the whealing reaction to allergen, compound 48/80, and histamine. these results suggest that h2 antagonist prevented the whealing reaction by changing the vas ...19836138882
slow responses mediated by alpha-adrenoceptors in the cardiac muscles of the monkey (macaca fuscata).the effects of phenylephrine on force of contraction and on slow action potentials were studied in the cardiac muscles of the japanese monkey (macaca fuscata). 1) the concentration-response curves for the positive inotropic effect of phenylephrine in the left atria and right ventricular papillary muscles were shifted to the right by either prazosin (10(-7) m) or propranolol (10(-6) m), and were further shifted in the presence of both prazosin and propranolol. 2) phenylephrine (10(-5) m) restored ...19846145393
failure to produce axon reflex-sweating in the volar skin of japanese monkey (macaca fuscata) and crab-eating monkey (macaca irus).the functional properties of the sweat glands and their innervation in the volar skin of three japanese monkeys and two crab-eating monkeys were investigated. the sweat glands responded to both cholinomimetic and adrenomimetic agents, the former being highly predominant in the sudorific effect. spontaneous emotional sweating was strongly or completely inhibited by atropine at 10(-8)-10(-7) g/ml, but not by dihydroergotamine at 10(-5)-10(-4) g/ml. axon reflex sweating could not be produced by nic ...19846151462
failure to produce axon reflex-sweating in the volar skin of japanese monkey (macaca fuscata) and crab-eating monkey (macaca irus).the functional properties of the sweat glands and their innervation in the volar skin of three japanese monkeys and two crab-eating monkeys were investigated. the sweat glands responded to both cholinomimetic and adrenomimetic agents, the former being highly predominant in the sudorific effect. spontaneous emotional sweating was strongly or completely inhibited by atropine at 10(-8)-10(-7) g/ml, but not by dihydroergotamine at 10(-5)-10(-4) g/ml. axon reflex sweating could not be produced by nic ...19846151462
infectious transmission of human t-cell leukemia virus to animals.an human t-cell leukemia virus (htlv)-producing cell line (ra-1) was established from rabbit lymphocytes by co-cultivation with lethally irradiated mt-2 cells. ra-1 cells were inoculated intravenously into a japanese monkey and rabbits. all animals responded with the production of antibodies to htlv. lymphocytes from the seroconverted animals were grown in the presence of t-cell growth factor (tcgf) or co-cultured with lymphocytes from seronegative healthy persons. the tcgf-grown cells, which we ...19846152756
demonstration of zonal projections from the cerebellar flocculus to vestibular nuclei in monkeys (macaca fuscata).purkinje cells in the flocculus of macaque monkeys were labeled by retrograde axonal transport of horseradish peroxidase from the vestibular nuclei. these neurons are organized in three adjacent, narrow bands which span all folia of the ipsilateral flocculus. the central band, 500-750 micrometer wide, projects to the medial vestibular nucleus, while the two adjacent bands, each 300-500 micrometer wide, innervate the superior vestibular nucleus. these three bands cover about one-half of the total ...19816172751
a retino-pulvinar projection in the macaque monkey as visualized by the use of anterograde transport of horseradish peroxidase.a direct retino-pulvinar connection was found in the japanese monkey (macaca fuscata) by the anterograde horseradish peroxidase (hrp) method. hrp injected into the vitreous cavity of one eye labeled a few small clusters of optic fiber terminals in the medial border regions of the inferior pulvinar nucleus bilaterally, with a contralateral predominance.19826180359
comparison of the responses of the simian and canine coronary circulations to autonomic drugs.we studied japanese monkeys, an anubis baboon, and dogs to determine possible differences in the responsiveness of the simian and the canine coronary vasculature to autonomic drugs. under ketamine and pentobarbital anesthesia the left anterior descending coronary artery was perfused with autologous blood at constant pressure. all drugs were injected intraarterially. in monkeys, acetylcholine and methacholine produced vasoconstriction followed by vasodilatation, and vasoconstriction was marked af ...19826182415
comparison of the responses of the simian and canine coronary circulations to autonomic drugs.we studied japanese monkeys, an anubis baboon, and dogs to determine possible differences in the responsiveness of the simian and the canine coronary vasculature to autonomic drugs. under ketamine and pentobarbital anesthesia the left anterior descending coronary artery was perfused with autologous blood at constant pressure. all drugs were injected intraarterially. in monkeys, acetylcholine and methacholine produced vasoconstriction followed by vasodilatation, and vasoconstriction was marked af ...19826182415
structure and carbohydrate histochemistry of the minor salivary glands of the japanese macaque (macaca fuscata yakui). 19826214751
nicorandil releases acetylcholine-induced sustained coronary arterial constriction in monkeys and baboons.the spasmolytic action of nicorandil on coronary circulation was investigated in 3 japanese monkeys (macaca fuscata), 1 rhesus monkey (macaca mulatta), and 1 anubis baboon (papio anubis) anesthetized with pentobarbital. the arterial bed of the left anterior descending coronary artery (lad) was perfused with autologous arterial blood at a constant pressure close to systolic arterial blood pressure. single injections of nicorandil (10-300 micrograms) into the lad produced a dose-dependent increase ...19846235383
nicorandil releases acetylcholine-induced sustained coronary arterial constriction in monkeys and baboons.the spasmolytic action of nicorandil on coronary circulation was investigated in 3 japanese monkeys (macaca fuscata), 1 rhesus monkey (macaca mulatta), and 1 anubis baboon (papio anubis) anesthetized with pentobarbital. the arterial bed of the left anterior descending coronary artery (lad) was perfused with autologous arterial blood at a constant pressure close to systolic arterial blood pressure. single injections of nicorandil (10-300 micrograms) into the lad produced a dose-dependent increase ...19846235383
brief report food-aversion conditioning in japanese monkeys (macaca fuscata): a dissociation of feeding in two separate situations. 19816272680
brief report food-aversion conditioning in japanese monkeys (macaca fuscata): a dissociation of feeding in two separate situations. 19816272680
alpha-adrenoceptors mediating the positive inotropic effect of phenylephrine in the right ventricular muscle of the monkey (macaca fuscata).the property of adrenoceptors mediating the positive inotropic effect (pie) in the ventricular muscle of the japanese monkey (macaca fuscata) was investigated by the use of phenylephrine (pe) and adrenoceptor antagonists. the intrinsic activity (0.6) and the pd2-value (5.41) for pe were comparable to those in other mammalian species. the beta-adrenoceptor antagonist, pindolol (3 x 10(-8) mol/l) shifted only the upper part of the concentration-response curve (crc) for pe to the right; the pd2-val ...19826281673
the confronting cisternae in neurons in the substantia gelatinosa of the spinal cord of rats and japanese monkeys.the neurons in the substantia gelatinosa of the spinal cord of the rat and japanese monkey were investigated electron microscopically and ultracytochemically. the confronting cisternae observed in the cytoplasm of the majority of gelatinosal neurons in both species were composed of closely apposed parallel cisternae with electron-dense flocculent material, and a continuity with the cisternae of the rough endoplasmic reticulum was often observed. ultracytochemically, the p-nitrophenylphosphatase ...19836309398
the confronting cisternae in neurons in the substantia gelatinosa of the spinal cord of rats and japanese monkeys.the neurons in the substantia gelatinosa of the spinal cord of the rat and japanese monkey were investigated electron microscopically and ultracytochemically. the confronting cisternae observed in the cytoplasm of the majority of gelatinosal neurons in both species were composed of closely apposed parallel cisternae with electron-dense flocculent material, and a continuity with the cisternae of the rough endoplasmic reticulum was often observed. ultracytochemically, the p-nitrophenylphosphatase ...19836309398
isolation in culture of a type c virus from a japanese monkey seropositive to adult t-cell leukemia-associated antigens.co-cultivation of lymphocytes from two japanese monkeys, one of which was seropositive to adult t-cell leukemia (atl)-associated antigens (atla), gave rise to a lymphoid cell line derived from the anti-atla negative monkey. this cell line harbors atla and type c virus particles identical in morphology to atl virus.19836309601
isolation in culture of a type c virus from a japanese monkey seropositive to adult t-cell leukemia-associated antigens.co-cultivation of lymphocytes from two japanese monkeys, one of which was seropositive to adult t-cell leukemia (atl)-associated antigens (atla), gave rise to a lymphoid cell line derived from the anti-atla negative monkey. this cell line harbors atla and type c virus particles identical in morphology to atl virus.19836309601
effects of histamine on mechanical performance and biochemical and electrical activity in the heart of monkeys (macaca fuscata).the properties of the cardiac effects of histamine on the isolated heart muscles of the japanese monkey (macaca fuscata) were investigated. histamine had a concentration-dependent positive inotropic effect on left atria and papillary muscles and a positive chronotropic effect on right atria. histamine increased the levels of cyclic amp and shortened the duration of the action potential in purkinje fibers, measures of its biochemical and electrophysiological effects. all of these effects of hista ...19836311566
na, k-atpase activity, atp and pi concentrations in various regions of monkey heart and their relation to post-overdrive hyperpolarization.the relationship among na, k-atpase activity, atp and inorganic phosphate (pi) concentrations in functionally different regions of cardiac and skeletal muscles were studied in the japanese monkey (macaca fuscata). the activity of na, k-atpase was determined by the method of fiske and subbarow, and the concentrations of atp and pi, by isotachophoresis. the atp concentrations in several regions of cardiac and skeletal muscles correlated positively with the na, k-atpase activities and pi concentrat ...19836314006
prevalence of antibody to adult t-cell leukemia virus-associated antigens (atla) in japanese monkeys and other non-human primates.the prevalence of adult t-cell-leukemia virus (atlv) infection was examined in japanese monkeys living naturally in various parts of japan and in other species of non-human primates imported into and kept in japan. sera of 2,650 japanese monkeys from 41 troops throughout japan were tested. high incidences of anti-atlv-associated antigen (atla)-positive monkeys were found in most troops, not only in the endemic area of human atl(southwestern japan), but also in non-endemic areas. the incidence of ...19846319300
prevalence of antibody to adult t-cell leukemia virus-associated antigens (atla) in japanese monkeys and other non-human primates.the prevalence of adult t-cell-leukemia virus (atlv) infection was examined in japanese monkeys living naturally in various parts of japan and in other species of non-human primates imported into and kept in japan. sera of 2,650 japanese monkeys from 41 troops throughout japan were tested. high incidences of anti-atlv-associated antigen (atla)-positive monkeys were found in most troops, not only in the endemic area of human atl(southwestern japan), but also in non-endemic areas. the incidence of ...19846319300
[a long-term qualitative behavioral change following chronic methamphetamine administration in japanese monkeys (macaca fuscata)].changes in spontaneous behavior and behavioral response to various neuroactive agents following chronic methamphetamine (map) administration were assessed in 3 monkeys. the results obtained were: 1) daily administration of map (1 mg/kg) for 12 weeks resulted in a progressive qualitative alteration of behavior content including increased inhibition and staring, 2) such abnormal behavior was augmented during the chronic treatment and was reappeared by a test dose (0.2 mg/kg) of map after 2 or 4 we ...19836331689
[a long-term qualitative behavioral change following chronic methamphetamine administration in japanese monkeys (macaca fuscata)].changes in spontaneous behavior and behavioral response to various neuroactive agents following chronic methamphetamine (map) administration were assessed in 3 monkeys. the results obtained were: 1) daily administration of map (1 mg/kg) for 12 weeks resulted in a progressive qualitative alteration of behavior content including increased inhibition and staring, 2) such abnormal behavior was augmented during the chronic treatment and was reappeared by a test dose (0.2 mg/kg) of map after 2 or 4 we ...19836331689
presence of endogenous inhibitor of aromatic l-amino acid decarboxylase in monkey serum.in the course of our studies on the developmental changes of aromatic l-amino acid decarboxylase (aadc) in the serum of japanese monkeys (macaca fuscata fuscata), we found the presence of an endogenous inhibitor of aadc in all stages of monkey life. this inhibitor inhibited the serum enzyme activity completely with l-5-hydroxytryptophan (l-5-htp) as substrate, while the activity was partially inhibited with l-dopa as substrate. the inhibitor was non-dialyzable, but it could be removed from the m ...19846333583
presence of endogenous inhibitor of aromatic l-amino acid decarboxylase in monkey serum.in the course of our studies on the developmental changes of aromatic l-amino acid decarboxylase (aadc) in the serum of japanese monkeys (macaca fuscata fuscata), we found the presence of an endogenous inhibitor of aadc in all stages of monkey life. this inhibitor inhibited the serum enzyme activity completely with l-5-hydroxytryptophan (l-5-htp) as substrate, while the activity was partially inhibited with l-dopa as substrate. the inhibitor was non-dialyzable, but it could be removed from the m ...19846333583
immunohistochemical study on the localization of serotonin fibers and terminals in the spinal cord of the monkey (macaca fuscata).a modified procedure of pap-immunohistochemistry with the use of a rabbit antiserum against serotonin was applied to investigate the pattern of serotonin-containing nerve fibers in the spinal cord of the monkey, macaca fuscata. the majority of descending serotonin fibers in the white matter is located immediately below the pia mater in the ventrolateral funiculi. lamina i and the outer zone of lamina ii are supplied with numerous serotonin fibers. in the intermediate gray, two prominent bundles ...19836339064
immunohistochemical demonstration of serotonin nerve fibers in the neocortex of the monkey (macaca fuscata).using a peroxidase-antiperoxidase immunohistochemical method, the distribution of serotonin nerve fibers was studied in the neocortex of the monkey (macaca fuscata). all layers of the neocortex showed evidence of serotonin fibers, both fine and thick. unlike the distribution in rodents, different patterns of distribution were noted in each neocortex of the primate. among the cortical areas--area 4, 3-1-2, 17, 18, 41 and 42--the primary visual cortex (area 17) contained the highest density of imm ...19836342473
[establishment and characterization of atlv-producing cell lines].peripheral blood lymphocytes from a japanese monkey (macaca fuscata) were co-cultivated with lethally irradiated mt-2 cells that carry abundant type c virus particles (atlv) isolated from a patient with adult t-cell leukemia (atl). after six weeks, a lymphoid cell line designated si-1 was established from the simian lymphocytes. the si-1 line was e-, sig-, leu-1-, oki1+, ebna-, atla+ and atlv+. co-cultivation of peripheral blood lymphocytes from three anti-atla positive and two negative healthy ...19836349544
distribution of c cells in monkey thyroid glands as studied by the immunoperoxidase method using anti-calcitonin and anti-c-thyroglobulin antisera.the distribution of c cells in the thyroid glands of eight young adult monkeys (4 macaca fuscata and 4 macaca irus) was investigated by complete serial sections utilizing the immunoperoxidase method with anti-human calcitonin and anti-dog c-thyroglobulin antisera. the secretory granules of monkey c cells were strongly immunoreactive to both antisera. a markedly uneven distribution of c cells was found. the c cells were distributed in a small area restricted to the dorsomedial portion of the lobe ...19836349577
crf-immunoreactive nerve fibers in the circumventricular organs of the monkey, macaca fuscata.the occurrence of crf (corticotropin-releasing factor)-immunoreactive nerve fibers in the circumventricular organs of adult male monkeys, macaca fuscata, was studied on serially sectioned brains, by means of the peroxidase-antiperoxidase technique in combination with a highly specific and sensitive crf antiserum. crf-containing nerve fibers were found in high concentrations in the infundibulum and, in addition, in small numbers in the posterior lobe, organum vasculosum laminae terminalis, subfor ...19836349821
qualitative and quantitative changes in plasma luteinizing hormone (lh) under stimulation by intravenous infusion of synthetic luteinizing hormone-releasing hormone (lhrh) in japanese monkeys (macaca fuscata) as assessed by electrofocusing.using 5 adult japanese monkeys (macaca fuscata) of both sexes, the qualitative and quantitative changes in plasma lh caused by lhrh administration were examined before and after castration. five hundred micrograms synthetic lhrh was infused for 2 hrs and blood samples were obtained every 15 min for 5 hrs under ketamine hydrochloride anesthesia. plasma lh levels were determined by an in vitro bioassay using the mouse testis interstitial cell preparation. the lhrh infusion induced a biphasic relea ...19836349979
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