| purification and genetic characterisation of the novel bacteriocin ls2 produced by the human oral strain lactobacillus salivarius bgho1. | the aim of this study was to investigate the antimicrobial potential of lactobacillus salivarius bgho1, a human oral strain with probiotic characteristics and a broad inhibitory spectrum both against gram-positive and gram-negative pathogens. here we present the bacteriocin ls2, an extremely ph- and heat-stable peptide with antilisterial activity. ls2 is a novel member of the class iid bacteriocins, unique among all currently characterised bacteriocins. it is somewhat similar to putative bacteri ... | 2012 | 22739096 |
| heterophil phagocytic activity stimulated by lactobacillus salivarius l61 and l55 supplementation in broilers with salmonella infection. | newborn chicks are susceptible to salmonella enterica serovar enteritidis (se). the objective of this study was to evaluate the effect of lactobacillus probiotic isolated from chicken feces on heterophil phagocytosis in broiler chicks. a total of 150 newborn broiler chicks were divided into 5 groups (30 chicks per group) as follows: group 1 (normal control), given feed and water only, group 2 (positive control) given feed, water and se infection, group 3 (l61 treated) given feed, water, se infec ... | 2015 | 26580288 |
| impact of environmental factors on bacteriocin promoter activity in gut-derived lactobacillus salivarius. | bacteriocin production is regarded as a desirable probiotic trait that aids in colonization and persistence in the gastrointestinal tract (git). strains of lactobacillus salivarius, a species associated with the git, are regarded as promising probiotic candidates and have a number of associated bacteriocins documented to date. these include multiple class iib bacteriocins (salivaricin t, salivaricin p, and abp-118) and the class iid bacteriocin bactofencin a, which show activity against medicall ... | 2015 | 26341205 |
| effect of lactobacillus salivarius on th1/th2 cytokines and the number of spleen cd4⁺ cd25⁺ foxp3⁺ treg in asthma balb/c mouse. | bronchial asthma is a chronic airway inflammatory disease that involves t lymphocytes. | 2015 | 26339333 |
| effect of lactobacillus salivarius bacteriocin abp118 on the mouse and pig intestinal microbiota. | lactobacilli are gram-positive bacteria that are a subdominant element in the human gastrointestinal microbiota, and which are commonly used in the food industry. some lactobacilli are considered probiotic, and have been associated with health benefits. however, there is very little culture-independent information on how consumed probiotic microorganisms might affect the entire intestinal microbiota. we therefore studied the impact of the administration of lactobacillus salivarius ucc118, a micr ... | 2012 | 22363561 |
| divergent metabolic outcomes arising from targeted manipulation of the gut microbiota in diet-induced obesity. | the gut microbiota is an environmental regulator of fat storage and adiposity. whether the microbiota represents a realistic therapeutic target for improving metabolic health is unclear. this study explored two antimicrobial strategies for their impact on metabolic abnormalities in murine diet-induced obesity: oral vancomycin and a bacteriocin-producing probiotic (lactobacillus salivarius ucc118 bac(+)). | 2013 | 22345653 |
| effect of oral bacteria on the mechanical behavior of titanium dental implants. | this study sought to determine whether the mechanical properties of titanium dental implants changed after exposure to bacteria. | 2016 | 22299080 |
| impact of exopolysaccharide production on functional properties of some lactobacillus salivarius strains. | the aim of this work was to characterize functional properties of lactobacillus salivarius strains isolated from chicken feces. detection of genes responsible for exopolysaccharide (eps) production revealed that all strains harbored a dextransucrase gene, but p-gtf gene was only detected in strain e4. analysis of eps production levels showed significant alterations among strains tested. biofilm formation was found to be medium composition dependant, and there was a negative correlation with biof ... | 2015 | 26267164 |
| in vitro and in vivo screening of native lactic acid bacteria toward their selection as a probiotic in broiler chickens. | among 360 isolates from the gastrointestinal tract (git) of broilers, eleven isolates which showed in vitro probiotic properties were identified and selected for further tests. after the in vitro screening, three strains were chosen for the in vivo study of persistence of fresh cultures and then one strain was selected for the in vivo study of persistence of lyophilized culture. lyophilized lactobacillus salivarius dspv 001p was capable of persisting in broilers during a complete rearing, even 2 ... | 2015 | 26267089 |
| the oral and gut microbiomes are perturbed in rheumatoid arthritis and partly normalized after treatment. | we carried out metagenomic shotgun sequencing and a metagenome-wide association study (mgwas) of fecal, dental and salivary samples from a cohort of individuals with rheumatoid arthritis (ra) and healthy controls. concordance was observed between the gut and oral microbiomes, suggesting overlap in the abundance and function of species at different body sites. dysbiosis was detected in the gut and oral microbiomes of ra patients, but it was partially resolved after ra treatment. alterations in th ... | 2015 | 26214836 |
| complete genome sequence of lactobacillus salivarius ren, a probiotic strain with anti-tumor activity. | lactobacillus salivarius ren (lsr) (cgmcc no. 3606) is a probiotic strain that was isolated from the feces of a healthy centenarian living in bama, guangxi, china. previous studies have shown that this strain decreases 4-nitroquinoline 1-oxide (4-nqo)-induced genotoxicity in vitro. it also suppresses 4-nqo-induced oral carcinogenesis and 1,2-dimethylhydrazine (dmh)-induced colorectal carcinogenesis, and therefore may be used as an adjuvant therapeutic agent for cancer. here, we report the comple ... | 2015 | 26133929 |
| efficacy and safety of probiotic-supplemented triple therapy for eradication of helicobacter pylori in children: a systematic review and network meta-analysis. | the aim of this study was to identify the best probiotic supplementation in triple therapy for pediatric population with helicobacter pylori infection. | 2017 | 28681177 |
| to add or not to add probiotics to infant formulae? an updated systematic review. | we updated evidence on the effects of the administration of probiotic-supplemented infant formulae (if) compared with unsupplemented if. five databases were searched up to september 2016 for randomised controlled trials. twenty publications were identified, including five new rcts. supplementation of if with bifidobacterium lactis bb12, either alone or with streptococcus thermophilus, had no effect on growth, respiratory illness, antibiotic use, stool frequency or consistency. however, there was ... | 2017 | 28856907 |
| functional role of oppa encoding an oligopeptide-binding protein from lactobacillus salivarius ren in bile tolerance. | lactobacillus salivarius is a member of the indigenous microbiota of the human gastrointestinal tract (git), and some l. salivarius strains are considered as probiotics. bile tolerance is a crucial property for probiotic bacteria to survive the transit through the git and exert their beneficial effects. in this work, the functional role of oppa encoding an oligopeptide transporter substrate-binding protein from l. salivarius ren in bile salt tolerance was investigated. in silico analysis reveale ... | 2015 | 25998246 |
| strain-specific inhibition of the adherence of uropathogenic bacteria to bladder cells by probiotic lactobacillus spp. | urinary tract infections (utis), one of most common infections worldwide, face high recurrence rates and increasing antimicrobial resistance. probiotic bacteria, especially of the genus lactobacillus, are considered a promising preventive and/or treatment therapy against utis. in order to elucidate the mechanisms involved in these beneficial effects, we studied the impact of different lactobacillus strains (lactobacillus salivarius ucm572, l. plantarum clc17 and l. acidophilus 01) in the adheren ... | 2017 | 28402532 |
| indigenous lactobacilli strains of food and human sources reverse enteropathogenic e. coli o26:h11-induced damage in intestinal epithelial cell lines: effect on redistribution of tight junction proteins. | the aim of the study was to investigate the neutralizing effect of lactobacilli isolated from indigenous food and human sources on enteropathogenic escherichia coli (epec) o26 : h11-induced epithelial barrier dysfunction in vitro. this was assessed by transepithelial electrical resistance (teer) and permeability assays using intestinal cell lines, ht-29 and caco-2. furthermore, the expression and distribution of tight junction (tj) proteins were analysed by qrt-pcr and immunofluorescence assay, ... | 2017 | 28771130 |
| effect of ph and dilution rate on specific production rate of extra cellular metabolites by lactobacillus salivarius uco_979c in continuous culture. | the effect of ph and dilution rate on the production of extracellular metabolites of lactobacillus salivarius uco_979 was studied. the experiments were carried out in continuous mode, with chemically defined culture medium at a temperature of 37 °c, 200 rpm agitation and synthetic air flow of 100 ml/min. ethanol, acetic acid, formic acid, lactic acid and glucose were quantified through hplc, while exopolysaccharide (eps) was extracted with ethanol and quantified through the dubois method. the re ... | 2015 | 25805342 |
| urinary metabolomic fingerprinting after consumption of a probiotic strain in women with mastitis. | infectious mastitis is a common condition among lactating women, with staphylococci and streptococci being the main aetiological agents. in this context, some lactobacilli strains isolated from breast milk appear to be particularly effective for treating mastitis and, therefore, constitute an attractive alternative to antibiotherapy. a (1)h nmr-based metabolomic approach was applied to detect metabolomic differences after consuming a probiotic strain (lactobacillus salivarius ps2) in women with ... | 2014 | 24880136 |
| converging effects of a bifidobacterium and lactobacillus probiotic strain on mouse intestinal physiology. | evidence has grown to support the efficacy of probiotics in the management of gastrointestinal disorders, many of which are associated with dysregulated fluid and electrolyte transport. a growing body of evidence now suggests that the host microbiota and probiotics can influence intestinal ion transport and that these effects often occur in a strain-dependent manner. in this study, we sought to investigate the effects of two therapeutically relevant organisms, bifidobacterium infantis 35,624 and ... | 2014 | 24852567 |
| aggregation factor as an inhibitor of bacterial binding to gut mucosa. | modern research in the area of probiotics is largely devoted to discovering factors that promote the adherence of probiotic candidates to host mucosal surfaces. the aim of the present study was to test the role of aggregation factor (aggl) and mucin-binding protein (mbpl) from lactococcus sp. in adhesion to gastrointestinal mucosa. in vitro, ex vivo, and in vivo experiments in rats were used to assess the adhesive potential of these two proteins expressed in heterologous host lactobacillus saliv ... | 2014 | 24823989 |
| regulation of host weight gain and lipid metabolism by bacterial bile acid modification in the gut. | alterations in the gastrointestinal microbiota have been implicated in obesity in mice and humans, but the key microbial functions influencing host energy metabolism and adiposity remain to be determined. despite an increased understanding of the genetic content of the gastrointestinal microbiome, functional analyses of common microbial gene sets are required. we established a controlled expression system for the parallel functional analysis of microbial alleles in the murine gut. using this app ... | 2014 | 24799697 |
| lactobacillus salivarius ren prevent the early colorectal carcinogenesis in 1, 2-dimethylhydrazine-induced rat model. | the objective of this study was to investigate the impact of lactobacillus salivarius ren (ls) on modulating colonic micro flora structure and influencing host colonic health in a rat model with colorectal precancerous lesions. | 2014 | 24754742 |
| efficient production of lactic acid from sweet sorghum juice by a newly isolated lactobacillus salivarius cgmcc 7.75. | sweet sorghum juice was a cheap and renewable resource, and also a potential carbon source for the fermentation production of lactic acid (la) by a lactic acid bacterium. one newly isolated strain lactobacillus salivarius cgmcc 7.75 showed the ability to produce the highest yield and optical purity of la from sweet sorghum juice. studies of feeding different concentrations of sweet sorghum juice and nitrogen source suggested the optimal concentrations of fermentation were 325 ml l(-1) and 20 g l ... | 2013 | 24426133 |
| microencapsulation of functional strains by high pressure homogenization for a potential use in fermented milk. | this study was aimed to evaluate the potential of high pressure homogenization for the microencapsulation of two probiotic lactic acid bacteria, lactobacillus paracasei a13 and lactobacillus salivarius subsp. salivarius cet 4063 to produce functional fermented milks. microcapsules of the considered functional microorganisms were obtained by hph treatments at 50mpa in the presence of sodium alginate and vegetable oil. the microencapsulated microorganisms were then inoculated as adjuncts to produc ... | 2017 | 28578048 |
| lactobacillus salivarius: bacteriocin and probiotic activity. | lactic acid bacteria (lab) antimicrobial peptides typically exhibit antibacterial activity against food-borne pathogens, as well as spoilage bacteria. therefore, they have attracted the greatest attention as tools for food biopreservation. in some countries lab are already extensively used as probiotics in food processing and preservation. lab derived bacteriocins have been utilized as oral, topical antibiotics or disinfectants. lactobacillus salivarius is a promising probiotic candidate commonl ... | 2013 | 24010610 |
| effects of selected feed additives on the performance of laying hens given a diet rich in maize dried distiller's grains with solubles (ddgs). | 1. a total of 192 isa brown hens were given diets containing a high concentration of maize dried distiller's grains with solubles (ddgs) and the effect of selected feed additives on laying performance and egg quality was determined. 2. birds were allocated to 8 treatment groups with 12 replicates (cages) of two hens and were given, from week 26 to 55, iso-caloric and iso-nitrogenous experimental diets with or without a high concentration of ddgs (200 g/kg). the diet containing ddgs was not suppl ... | 2013 | 23826901 |
| targeting the microbiota to address diet-induced obesity: a time dependent challenge. | links between the gut microbiota and host metabolism have provided new perspectives on obesity. we previously showed that the link between the microbiota and fat deposition is age- and time-dependent subject to microbial adaptation to diet over time. we also demonstrated reduced weight gain in diet-induced obese (dio) mice through manipulation of the gut microbiota with vancomycin or with the bacteriocin-producing probiotic lactobacillus salivarius ucc118 (bac(+)), with metabolic improvement ach ... | 2013 | 23762426 |
| microbiomes of site-specific dental plaques from children with different caries status. | the oral microbiota associated with the initiation and progression of dental caries has yet to be fully characterized. the human oral microbe identification using next-generation sequencing (homings) approach was used to analyze the microbiomes of site-specific supragingival dental plaques from children with different caries status. fifty-five children (2 to 7 years of age) were assessed at baseline and at 12 months and grouped as caries free (cf), caries active with enamel lesions (cae), and ca ... | 2017 | 28507066 |
| effect of microencapsulation of lactobacillus salivarus 29 into alginate/chitosan/alginate microcapsules on viability and cytokine induction. | harsh gastric condition causes low bioavailability of probiotics when supplied orally. polymeric encapsulation has successfully protected bacteria from harsh gastric condition and ultimately increased persistency and multiplication at the targeted region. in this study, we encapsulated ls29 into aca microcapsules and characterized them. the survivability and release of ls29 from ls29-loaded aca microcapsules in sgf and sif were studied. encapsulation efficiency of ls29 in aca microcapsules was 9 ... | 2012 | 22304243 |
| potential of probiotic strains to modulate the inflammatory responses of epithelial and immune cells in vitro. | lactobacilli are important human commensal microbiota that are considered to be probiotic as they have been shown to reduce pathogenic infections and chronic inflammation. this study compared 4 strains of lactobacilli for their probiotic potential. these 4 strains showed varying capacities for adhesion and cytokine induction (interleukin [il]-8 and il-10) in different human epithelial cells, such as primary cultures of buccal cavity cells, and established cell lines derived from epithelia of the ... | 2013 | 23686123 |
| lactobacillus salivarius ren inhibits rat oral cancer induced by 4-nitroquioline 1-oxide. | despite significant advances in cancer therapy, cancer-related mobility and mortality are still rising. alternative strategies such as cancer prevention thus become essential. probiotics represent an emerging option for cancer prevention, but studies are limited to colon cancers. the efficiency of probiotics in the prevention of other cancers and the correlative mechanism remains to be explored. a novel probiotics lactobacillus salivarius ren (l. salivarius ren) was isolated from centenarians at ... | 2013 | 23658366 |
| codon optimisation to improve expression of a mycobacterium avium ssp. paratuberculosis-specific membrane-associated antigen by lactobacillus salivarius. | subunit and dna-based vaccines against mycobacterium avium ssp. paratuberculosis (map) attempt to overcome inherent issues associated with whole-cell formulations. however, these vaccines can be hampered by poor expression of recombinant antigens from a number of disparate hosts. the high g+c content of map invariably leads to a codon bias throughout gene expression. to investigate if the codon bias affects recombinant map antigen expression, the open reading frame of a map-specific antigen mptd ... | 2013 | 23620276 |
| changing of fecal flora and clinical effect of l. salivarius ls01 in adults with atopic dermatitis. | to evaluate cytokine stimulation with 3 strains of lactobacillus salivarius in vitro and to assess changes in intestinal microflora and clinical improvements in adults with atopic dermatitis (ad) induced by the strain showing the best immunomodulatory features. | 2012 | 22955359 |
| in vitro screening of lactobacilli isolated from chicken excreta to control salmonella enteritidis and typhimurium. | 1. the aim of this work was to select lactic acid bacteria (lab) strains from chicks and hens of egg-laying strains for potential use to control salmonellae. 2. nineteen lab strains obtained from culture collections, and 24 strains isolated from excreta of laying hens and chicks, were evaluated for inhibitory capacities against two salmonella serotypes using a "spot-the-lawn" technique and other in vitro properties that could be predictive of antimicrobial activity. 3. the size of the inhibition ... | 2012 | 22646783 |
| effects of a lactobacillus salivarius probiotic intervention on infection, cold symptom duration and severity, and mucosal immunity in endurance athletes. | the purpose of this study was to examine the effects of a probiotic supplement during 4 mo of spring training in men and women engaged in endurance-based physical activities on incidence of upper respiratory tract infections (urti) and mucosal immune markers. sixty-six highly active individuals were randomized to probiotic (n = 33) or placebo (n = 33) groups and, under double-blind procedures, received probiotic (pro: lactobacillus salivarius, 2 × 1010 bacterium colony-forming units) or placebo ... | 2012 | 22645171 |
| influence of adhesion and bacteriocin production by lactobacillus salivarius on the intestinal epithelial cell transcriptional response. | lactobacillus salivarius strain ucc118 is a human intestinal isolate that has been extensively studied for its potential probiotic effects in human and animal models. the objective of this study was to determine the effect of l. salivarius ucc118 on gene expression responses in the caco-2 cell line to improve understanding of how the strain might modulate intestinal epithelial cell phenotypes. exposure of caco-2 cells to ucc118 led to the induction of several human genes (tnfaip3, nfkbia, and bi ... | 2012 | 22610429 |
| genome sequence of lactobacillus salivarius smxd51, a potential probiotic strain isolated from chicken cecum, showing anti-campylobacter activity. | we report the draft genome sequence of lactobacillus salivarius smxd51, isolated from the cecum of healthy chickens showing an activity against campylobacter--the food-borne pathogen that is the most common cause of gastroenteritis in the european union (eu)--and potentially interesting features for a probiotic strain, explaining our interest in it. | 2012 | 22582370 |
| characterization of lactobacillus salivarius cect 5713, a strain isolated from human milk: from genotype to phenotype. | lactobacillus salivarius cect 5713, isolated from human milk, has immunomodulatory, anti-inflammatory and antiinfectious properties, as revealed by several in vitro and in vivo assays, which suggests a strong potential as a probiotic strain. in this work, the relationships between several genetic features of l. salivarius cect 5713 and the corresponding phenotypes were evaluated. although it contains a plasmid-encoded bacteriocin cluster, no bacteriocin biosynthesis was observed, possibly due to ... | 2012 | 22526789 |
| optimization of low-cost culture media for the production of biomass and bacteriocin by a urogenital lactobacillus salivarius strain. | the aim of this work was to formulate a culture medium of lower cost than conventional laboratory media, in order to simultaneously obtain high amounts of both biomass and bacteriocin of vaginal lactobacillus salivarius crl 1328. the growth assays under different culture conditions were performed by using a 2(8-2) central composite experimental design, with a central point and sixteen additional points. the factors taken into consideration were glucose, lactose, yeast extract, tryptone, ammonium ... | 2010 | 26780896 |
| lactobacillus salivarius nk02: a potent probiotic for clinical application in mouthwash. | a specific strain of naturally occurring oral lactobacilli was isolated and identified based on morphological, biochemical, and 16s rrna gene sequencing. the phylogenetic affiliation of the isolate confirmed that the nk02 strain had close association with the lactobacillus salivarius. an effective mouthwash was developed for treatment of periodontitis and suppression of the indicator bacterium aggregatibacter actinomycetemcomitans which is an obvious pathogen of periodontal disease. the mouthwas ... | 2017 | 28631250 |
| administration of lactobacillus salivarius li01 or pediococcus pentosaceus li05 prevents ccl4-induced liver cirrhosis by protecting the intestinal barrier in rats. | alterations in the gut microbiome have been reported in liver cirrhosis, and probiotic interventions are considered a potential treatment strategy. this study aimed to evaluate the effects and mechanisms of lactobacillus salivarius li01, pediococcus pentosaceus li05, lactobacillus rhamnosus gg, clostridium butyricum miyairi and bacillus licheniformis zhengchangsheng on ccl4-induced cirrhotic rats. only administration of li01 or li05 prevented liver fibrosis and down-regulated the hepatic express ... | 2017 | 28761060 |
| bifidobacterium animalis subsp. lactis 420 mitigates the pathological impact of myocardial infarction in the mouse. | there is a growing appreciation that our microbial environment in the gut plays a critical role in the maintenance of health and the pathogenesis of disease. probiotic, beneficial gut microbes, administration can directly attenuate cardiac injury and post-myocardial infarction (mi) remodelling, yet the mechanisms of cardioprotection are unknown. we hypothesised that administration of bifidobacterium animalis subsp. lactis 420 (b420), a probiotic with known anti-inflammatory properties, to mice w ... | 2017 | 28409534 |
| supplemental thymol and carvacrol increases ileum lactobacillus population and reduces effect of necrotic enteritis caused by clostridium perfringes in chickens. | necrotic enteritis (ne) caused by clostridium perfringens is one of the most detrimental infectious diseases in poultry. this study examined the effect of blends of essential oils (beos) (25% thymol and 25% carvacrol) on ne and bacterial dynamics and functions in chicks challenged with c. perfringens. chicks were assigned to a control diet and beos diet (control diet + 120 mg/kg beos), were challenged with c. perfringens from days 14 to 20 and were killed on day 21 for assessment. supplementatio ... | 2017 | 28779076 |
| isolation and selection of potential probiotic bacteria from the pig gastrointestinal tract. | the present study aimed to isolate bacterial strains from the pig gastrointestinal tract that have antagonistic activity against potential pathogens and are able to produce antimicrobial compounds. that ability would be a first requirement for the strains' possible use as probiotics. samples obtained from pig intestinal mucosa and contents were screened for the presence of antagonistic activity against pathogenic indicator strains of escherichia coli, salmonella, and listeria by means of the dou ... | 2017 | 28744832 |
| impact of lyophilized lactobacillus salivarius dspv 001p administration on growth performance, microbial translocation, and gastrointestinal microbiota of broilers reared under low ambient temperature. | this study was undertaken with the aim of investigating the effects of dietary supplementation of probiotic strain lactobacillus salivarius dspv 001p on growth performance, microbial translocation, and gastrointestinal microbiota of broilers reared under low ambient temperature. two hundred and forty, one-day-old male cobb broilers were randomly distributed into two treatment groups, a probiotic group and a control group, with four replicates per treatment and 30 broilers per replicate. the temp ... | 2017 | 28743079 |
| inhibition of fusarium solani infection in murine keratocytes by lactobacillus salivarius ssp. salivarius jcm1231 culture filtrate in vitro. | to explore the inhibitory activity of lactobacillus salivarius ssp. salivarius jcm1231 (l. salivarius jcm1231) culture filtrate against fusarium solani (f. solani) and its effects on murine keratocytes (mks) infected with f. solani. | 2017 | 28636459 |
| selection of potential probiotic lactobacillus with inhibitory activity against salmonella and fecal coliform bacteria. | three hundred and sixty presumptive lactic acid bacteria (lab) isolated from pregnant sows, newborn, suckling, and weaned piglets were preliminarily screened for anti-salmonella activity. fifty-eight isolates consisting of lactobacillus reuteri (n = 32), lactobacillus salivarius (n = 10), lactobacillus mucosae (n = 8), lactobacillus johnsonii (n = 5), and lactobacillus crispatus (n = 3) were selected and further characterized for probiotic properties including production of antimicrobial substan ... | 2017 | 28712023 |
| supplementation of lactobacilli improves growth, regulates microbiota composition and suppresses skeletal anomalies in juvenile pike-perch (sander lucioperca) reared in recirculating aquaculture system (ras): a pilot study. | this research aimed to test the effects of lactobacilli, applied to cultured pike-perch, either through hydrolyzed otohime fish diet, or through artemia nauplii, on fish growth, microbiota balance and skeletal development. on the 12th day post hatching (dph) fish were divided into following treatment groups: two groups received the combination of otohime and nauplii enriched either with lactobacillus paracasei bghn14+lactobacillus rhamnosus bgt10 or with lactobacillus reuteri bggo6-55+lactobacil ... | 2017 | 28777955 |
| effects of a lactobacillus salivarius mixture on performance, intestinal health and serum lipids of broiler chickens. | the ban or severe restriction on the use of antibiotics in poultry feeds to promote growth has led to considerable interest to find alternative approaches. probiotics have been considered as such alternatives. in the present study, the effects of a lactobacillus mixture composed from three previously isolated lactobacillus salivarius strains (ci1, ci2 and ci3) from chicken intestines on performance, intestinal health status and serum lipids of broiler chickens has been evaluated. supplementation ... | 2017 | 28459856 |
| differential intestinal anti-inflammatory effects of lactobacillus fermentum and lactobacillus salivarius in dss mouse colitis: impact on micrornas expression and microbiota composition. | to compare the intestinal anti-inflammatory effects of two probiotics lactobacillus fermentum and lactobacillus salivarius in mouse colitis, focusing on their impact on selected mirnas and microbiota composition. | 2017 | 28752563 |
| lactococcus lactis and lactobacillus salivarius bgbu1-4 differently modulate early immunological response of wistar rats co-administered with listeria monocytogenes. | in the light of the increasing resistance of bacterial pathogens to antibiotics, one of the main global strategies in applied science is development of alternative treatments, which would be safe both for the host and from the environmental perspective. accordingly, the aim of this study was to test whether two lactic acid bacteria (lab) strains, lactococcus lactis bgbu1-4 and lactobacillus salivarius bgho1, could be applied as safe supplements for listeria infection. two major research objectiv ... | 2017 | 28856909 |
| evasin-displaying lactic acid bacteria bind different chemokines and neutralize cxcl8 production in caco-2 cells. | chemokines are key signals in the immune system and play an important role as proinflammatory mediators in the pathology of inflammatory bowel disease and colorectal cancer, making them an important target for therapy. recombinant lactic acid bacteria (lab) were engineered to bind cc and cxc chemokines by displaying chemokine-binding proteins evasin-1, evasin-3 and evasin-4 on their surface. evasin genes were cloned into lactococcal surface display vector and overexpressed in l. lactis nz9000 an ... | 2017 | 28736998 |
| lactobacillus salivarius infection as a postoperative complication after bariatric surgery. | | 2017 | 28527676 |