| erythromycin production kinetics. | | 1973 | 4802465 |
| selective tryptophan oxidation in the antitumor protein neocarzinostatin and effects on conformation and biological activity. | | 1974 | 4813363 |
| pigments and isoprenoid compounds in extremely and moderately halophilic bacteria. | | 1974 | 4822788 |
| production of flavine-adenine dinucleotide from riboflavine by a mutant of sarcina lutea. | a study was made to develop a new method for the production of flavine-adenine dinucleotide (fad) from riboflavine and adenine by a mutant of sarcina lutea deficient in the enzyme adenosine deaminase. it was found that this strain could convert exogenously supplemented riboflavine to extracellular fad. the yields of fad were increased by addition of d-cycloserine in the culture medium. the culture conditions for fad production were investigated under the addition of d-cycloserine, and increased ... | 1974 | 4824882 |
| microbiological study of a hypersaline lake in french somaliland. | in a study of a lake having a higher concentration of salts than the dead sea, all of the heterotrophic bacteria isolated were aerobes; no strictly anaerobic strains were found. ninety percent of the strains were euryhalines and ten percent were strict halophiles. the extreme halophiles belonged to the species halobacterium trapanicum and halococcus morrhuae. | 1974 | 4833284 |
| preparation of succinyl neocarzinostatin. | all amino groups in a proteinous antitumor antibiotic, neocarzinostatin, were reacted with succinic anhydride yielding bis-n-succinyl neocarzinostatin which retained biological activity in vitro against human cell lines and a bacterium. amino groups in neocarzinostatin do not appear to play an important role in the activity. | 1974 | 4840443 |
| [determination of residues of chloramphenicol in rainbow trout (salmo gairdneri) and atlantic salmon (salmo salar) (author's transl)]. | | 1974 | 4840814 |
| production of coenzyme a by sarcina lutea. | to develop an efficient method for the production of coenzyme a (coa), optimal conditions for its formation from pantothenic acid, cysteine, and adenine were studied. a number of microorganisms were screened for production of coa. strains belonging to the genera sarcina, bacillus, microbacterium, micrococcus, and serratia accumulated coa. among these, sarcina lutea was selected as the best organism, and the culture conditions for the production of coa were investigated with this organism. under ... | 1974 | 4844273 |
| [cocci carriers among patients at the dermatological clinic. ii. coccal flora isolated from the nose vestibule and the skin of various regions of the body]. | | 1974 | 4848313 |
| chemical modification of erythromycin: synthesis and preliminary bioactivity of selected amides and esters. | | 1974 | 4850998 |
| fate of oral 35s-cloxacillin in man. | | 1974 | 4852027 |
| rapid method for the radioisotopic analysis of gaseous end products of anaerobic metabolism. | a gas chromatographic procedure for the simultaneous analysis of (14)c-labeled and unlabeled metabolic gases from microbial methanogenic systems is described. h(2), ch(4), and co(2) were separated within 2.5 min on a carbosieve b column and were detected by thermal conductivity. detector effluents were channeled into a gas proportional counter for measurement of radioactivity. this method was more rapid, sensitive, and convenient than gas chromatography-liquid scintillation techniques. the gas c ... | 1974 | 4854029 |
| serum concentration and half-life of rifampicin after simultaneous oral administration of aminosalicylic acid or isoniazid. | | 1974 | 4854257 |
| the mechanism of prumycin action. | | 1974 | 4854949 |
| the antibiotic activity of cultures from fungal spores collected by a spore trap on permanent pasture. | | 1974 | 4857622 |
| ribosyl and deoxyribosyl transfer by bacterial enzyme systems. | the enzymatic transfer of ribose and deoxyribose residues in pyrimidine nucleosides to purines was catalyzed by cell-free extracts of various bacteria. almost all the strains belonging to enterobacteriaceae were capable of catalyzing the transfer reactions. the transfer activities were also detected among some bacterial strains of other families: pseudomonadaceae, corynebacteriaceae, micrococcaceae, bacteriaceae, and bacillaceae. the rates of the transfer reactions were greatly enhanced in the p ... | 1967 | 4863982 |
| drug resistance as influenced by inactivated sensitivity discs. | reports of staphylococci resistant to the semisynthetic penicillins stimulated a study of the factors influencing the stability of the drugs in discs. the behavior of penicillin g, methicillin, oxacillin, cloxacillin, and cephalothin discs under different humidity and temperature conditions is described. humidity was found to be the most significant factor in drug inactivation. storage of discs in a vacuum desiccator at -20 c provides maximal antibiotic stability. | 1968 | 4869619 |
| [study of the antibiotics of the endomycin group]. | | 1967 | 4871263 |
| gluconimycin, a new antibiotic. | | 1966 | 4872544 |
| identification of micrococcaceae in clinical bacteriology. | the cellular morphology, identifying physiological characteristics, and a key to the human genera of micrococcaceae are presented with flow charts for identification of aerobic and anaerobic isolates. these flow charts can be amended as desired, depending upon the degree of accuracy desired. micrococcaceae isolates in a 350-bed private general hospital during a 15-week period are tabulated to show relative numbers of the different genera and species, with their probable relationship to infection ... | 1968 | 4874454 |
| [use of the method of phage induction for the isolation and purification of antitumor antibiotics]. | | 1967 | 4874765 |
| output characteristics and clinical efficacy of ultrasonic nebulizers. | | 1968 | 4875003 |
| [preliminary therapeutic results in pediatrics of the use of a new antibiotic: cephaloridine]. | | 1966 | 4875303 |
| resistance of escherichia coli to penicillins. v. physiological comparison of two isogenic strains, one with chromosomally and one with episomally mediated ampicillin resistance. | two essentially isogenic strains of escherichia coli k-12 were compared: d31 had chromosomally and d1-r1 episomally mediated resistance to ampicillin. the two strains had the same ability to form colonies on ampicillin plates, but in other tests they were quite different. in serial dilution tests as well as in exponentially growing cultures, d1-r1 was far more resistant to ampicillin than was d31. the inoculum effect with d1-r1 was large and with d31 was rather small. on plates, d31 was more res ... | 1968 | 4877126 |
| disruption of bacterial cells by a synthetic zeolite. | the use of a synthetic zeolite (type 4a, union carbide corp., linde div., new york, n.y.) in a procedure for the preparation of pure cell wall fractions proved successful for many gram-positive, gram-negative, and acid-fast bacteria, as well as for some fungi. the technique, however, was found to be limited in effectiveness for rhodospirillum rubrum, gaffkya tetragena, and sarcina lutea, and not applicable to preparations of heat killed microorganisms. the possible mechanisms of zeolite action, ... | 1968 | 4877657 |
| amino acid coding in sarcina lutea and saccharomyces cerevisiae. | aminoacyl-trna's from sarcina lutea were tested for incorporation into protein in a heterologous system from escherichia coli or for biniding in a homologous system from sarcina lutea. aminoacyl-trna's from saccharomyces cerevisiae were tested for biniding in a homologous saccharomyces cerevisiae system. synthetic polyribonucleotides were used as messengers. the code which exists in sarcina lutea and saccharomyces cerevisiae is the same as in escherichia coli. | 1967 | 4886536 |
| radioresistance of bacteria as a function of p-hydroxymercuribenzoate binding. | | 1969 | 4888098 |
| screening of antiviral antibiotics from actinomycetes: correlation between antiviral activity, cytotoxicity and antibacterial activity. (studies on antiviral and antitumor antibiotics. xi). | | 1969 | 4895358 |
| interactions of small molecules with nucleic acids. i. mode of action of anthramycin. | | 1968 | 4898527 |
| distinctive sulphydryl responses in x-irradiated and in heat-treated micrococcus radiodurans. | | 1969 | 4898856 |
| the effect of age on the normal bacterial flora of the skin. | | 1969 | 4904210 |
| the normal flora of the human skin. | | 1969 | 4904211 |
| bacteriolytic spectrum of the enzyme produced by acanthamoeba castellanii. | | 1969 | 4905249 |
| scanning electron and phase-contrast microscopy of bacterial spores. | the three-dimensional immages of free and intrasporangial spores produced by scanning electron microscopy show surface structures not visible by phase-contrast microscopy. although fine surface detail is not elucidated by scanning electron microscopy, this technique does afford a definitive picture of the general shape of spores. spores of bacillus popilliae, b. lentimorbus, b. thuringiensis, b. alvei, b. cereus, and sarcina ureae have varying patterns of surface ridge formation, whereas spores ... | 1969 | 4907010 |
| biology of the mycobacterioses. studies on glucose oxidation during the interaction of alveolar macrophages and bacteria. | | 1968 | 4909583 |
| biology of the sugar-fermenting sarcinae. | | 1970 | 4909648 |
| [preliminary studies on the determination of biologically active rifomycin using the platelet method]. | | 1970 | 4913881 |
| [effect of permanent magnetic field on the sensitivity of a bacterial population to antibiotics]. | | 1970 | 4914041 |
| [effects of tylosin on the growth of bacteria]. | | 1970 | 4915386 |
| acid-fast granuloma in a turtle's eye. | | 1970 | 4916226 |
| antagonism by a gram-positive coccus. | | 1970 | 4921873 |
| [bacteriological studies of human ejaculates]. | | 1970 | 4922161 |
| [antibiotics possessing properties of leucine antimetabolites]. | | 1970 | 4922625 |
| infrared studies of dna's, their constituents and analogues. vi. denaturation of dna's from microorganisms. | | 1971 | 4925822 |
| [study of the biomass and lipids of paraffin-oxidizing ray fungi using microbiological tests]. | | 1971 | 4931588 |
| studies on bacteriocinogeny of streptococcus strains. i. bacteriocinogeny of strains of the streptococcus viridans group. | | 1971 | 4933384 |
| [changes in the microbial count in urine at room temperature]. | | 1971 | 4934655 |
| [effect of high vacuum on the activity of iron porphyrin enzymes in microorganisms]. | | 1971 | 4934693 |
| [effect of high vacuum on atp stability in microorganisms]. | | 1970 | 4935079 |
| [effect of light on the metabolism of non-photosynthesizing microorganisms]. | | 1971 | 4935598 |
| assay of antibiotic activity in live-virus poultry vaccines with micro-techniques. | | 1971 | 4938690 |
| [occurrence and origin of volatile primary amines in bacteria]. | | 1971 | 4938786 |
| [isolation, purification and physico-chemical properties of antibiotic lienomycin]. | | 1971 | 4939468 |
| a stable, biologically active indoxyl. | | 1971 | 4940627 |
| modification of radiation damage of bacteria by folic acid antagonists. | pittillo, robert f. (southern research institute, birmingham, ala.), mary lucas, robert t. blackwell, and carolyn woolley. modification of radiation damage of bacteria by folic acid antagonists. j. bacteriol. 90:1548-1551. 1965.-the folic acid analogues, 2,4-diamino-6-methylpteridine, amethopterin, and aminopterin, have been found to sensitize certain bacteria, especially escherichia coli, to the lethal action of ionizing irradiation. data are presented which indicate that (i) the compounds must ... | 1965 | 4955054 |
| studies on coumermycin, a new antibiotic. 3. structure of coumermycin a2. | | 1965 | 4955235 |
| continuous automatic microbiological assay of antibiotics. ii. | | 1965 | 4955794 |
| steroid lysis of protoplasts and effects of stabilizers and steroid antagonists. | six synthetic antimicrobial steroids were examined for indications of their mechanism of action. dequadin acetate, cetyl pyridinium chloride (cpc), and sodium deoxycholate were studied for comparison. aerated cells of sarcina lutea were washed, suspended in 1.06 m sucrose, and converted to protoplasts with 20 mug/ml of lysozyme. lysis was measured optically at 650 mmu as a decrease in optical density. screening tests with 50 mug/ml of each compound showed five steroids and cpc to be lytic. proto ... | 1965 | 4956242 |
| simultaneous spectral determination of both base composition and concentration of dna. | | 1966 | 4957282 |
| concerning the mechanism by which hadacidin potentiates the damaging action of ionizing irradiation on bacteria. | | 1966 | 4958825 |
| the structure-antimicrobial relation for valinomycin depsipeptides. | | 1965 | 4959379 |
| fusidic acid derivatives. i. relationship between structure and antibacterial activity. | | 1966 | 4959882 |
| simplified, accurate method for antibiotic assay of clinical specimens. | large glass plates are used for this modified agar-well diffusion assay method, allowing up to 81 replications on a single plate. with a specially designed agar punch, it is possible to prepare the small agar wells very quickly. the saving in serum resulting from fewer replications of standards with the large plates, and the small volume of the agar wells, makes it economically feasible to use pooled human serum for the standard antibiotic solutions. methods are described for preparing the stand ... | 1966 | 4959982 |
| effect of azasteroids on gram-positive bacteria. | a group of nitrogen-containing steroids closely related in structure was screened for antibacterial activity, by use of bacillus subtilis and sarcina lutea as the test organisms. the most active compounds were cholesterol derivatives containing a tertiary or quaternary nitrogen in, or attached to, the a ring. similar methyltestosterone or progesterone derivatives were inactive. all of the cholesterol derivatives that inhibited growth were surfactant, and, structurally, they would be classified a ... | 1967 | 4960181 |
| nucleosides. 33. n4-acylated 5-fluorocytosines and a direct synthesis of 5-fluoro-2'-deoxycytidine. | | 1966 | 4961226 |
| conversion of ddt to ddd by pathogenic and saprophytic bacteria associated with plants. | of 27 microorganisms examined, 23 plant pathogenic and saprophytic bacterial species were found to convert p,p' ddt to p,p' ddd under anaerobic conditions. the range of conversion of ddt (10 micrograms per milliliter) during an incubation of 14 days was from a trace to over 5 micrograms per milliliter, with the majority of the bacteria showing the greatest activity during the final 7-day period. there is evidence that metabolites of ddt other than ddd are also produced. | 1967 | 4961613 |
| topochemical approach in studies of the structure-activity relation: enantio-enniatin b. | | 1967 | 4961750 |
| immunological differentiation between cell walls of streptomycin-sensitive and streptomycin-dependent bacteria. | | 1967 | 4962215 |
| gamma-irradiation of deoxyribonucleic acid in dilute solutions. i. a sensitive method for detection of single-strand breaks in polydisperse dna samples. | | 1967 | 4962560 |
| [a method for the quantitative determination of the effects of drug combinations, applied to antibiotics]. | | 1967 | 4963681 |
| isolation and characterization of bacterial membranes. | | 1967 | 4965019 |
| fractionation of isolated bacterial membranes. | | 1967 | 4965662 |
| assay of antibiotics-streptomycin and chloramphenicol. | | 1966 | 4965924 |
| steroids. xxx. some indolocholestanes and indoloandrostanes. | | 1968 | 4966060 |
| studies on the antibacterial effects of negapillin in combination with other antibiotics and sulfa drugs. | | 1966 | 4966224 |
| [the bacterial content of raw and freeze-dried women's milk]. | | 1966 | 4967146 |
| ribosomal proteins of bacterial cells: strain- and species-specificity. | | 1968 | 4967207 |
| production of polyol dehydrogenases in bacteria. | | 1968 | 4967217 |
| ultraviolet bactericidal irradiation of ice. | we investigated the germicidal activity of 2,537 a ultraviolet (uv) radiation on bacteria in ice cubes of varying thickness and in aqueous suspensions beneath an ice layer. the test bacteria used were escherichia coli, serratia marcescens, bacillus subtilis, and sarcina lutea; aqueous suspensions of the selected organisms were frozen into ice cubes, 2 mm to 30 mm thick, at -20 c. the cubes were irradiated for 1 min, whereas the suspensions of bacteria were placed beneath an ice block (19 cm thic ... | 1968 | 4967756 |
| effects in hyperoxia upon microorganisms. i. membrane culture technique for exposing cells directly to test atmospheres. | a membrane culture technique was developed for directly exposing microorganisms to test atmospheres. inhibition and killing were calculated from comparisons with air-grown cultures. direct colony counts were used with low inocula. with mass inocula, plate colony counts and optical-density measurements were made on resuspended filter populations. bacteria, including escherichia coli, were more sensitive to oxygen than previously reported. with inocula of a few hundred cells per membrane, five of ... | 1968 | 4967757 |
| [demonstration of antibiotics in milk by means of the bacteriological method]. | | 1966 | 4968904 |
| metabolism of tryptophans by pseudomonas aureofaciens. vi. production of pyrrolnitrin by selected pseudomonas species. | twenty-nine strains of pseudomonas, classified as p. fluorescens biotype d or e or as p. multivorans, were examined for the production of pyrrolnitrin, an antifungal agent synthesized in p. aureofaciens. eight strains were shown to produce pyrrolnitrin in shake-flask fermentation. four cultures were from the multivorans taxon, and the remaining four were members of the fluorescens group. the antifungal agent produced in these strains was isolated and shown to be pyrrolnitrin by comparison with a ... | 1968 | 4968963 |
| [assimilation of amino acids by some bacteria and its application to the detection of an unknown compound]. | | 1967 | 4969286 |
| effects of high electric fields on micro-organisms. 3. lysis of erythrocytes and protoplasts. | | 1968 | 4969954 |
| ribosome formation and structure. | | 1968 | 4970633 |
| lytic effects of staphylococcal alpha-toxin and delta-hemolysin. | several preparations of staphylococcal alpha-toxin and delta-lysin were studied in order to compare hemolytic activity with capacity to lyse bacterial protoplasts. delta-lysin in relatively low concentration lysed protoplasts of sarcina lutea, protoplasts of streptococcus faecalis, and spheroplasts of escherichia coli. lysis of bacterial protoplasts by preparations of alpha-toxin appeared to be due to contamination of the preparations with delta-lysin. data comparing the protoplast-lysing activi ... | 1968 | 4970650 |
| [a new producer of mithramycin--act. atroolivaceus]. | | 1967 | 4970742 |
| [natural variability of the producer of amphotericin act. nodosus trejo in relation to antibiotic production]. | | 1968 | 4970744 |
| [determination of biological activity of polysynthetic penicillins by the agar diffusion method]. | | 1968 | 4970746 |
| evaluation of an automatic diluting device for microbiological applications. | | 1968 | 4970994 |
| [derivatives of dipheoro-acetic acid with antibacterial activity. 3]. | | 1968 | 4971381 |
| [on the washing of hands in a pediatric ward. on the advantage of combining an organic mercurial disinfectant with a hexachlorophene]. | | 1968 | 4971633 |
| synthesis of tetra-n-phenylalkylkanamycins and their antimicrobial activities. | | 1968 | 4973122 |
| comparison of the action of vantocil, cetrimide and chlorhexidine on escherichia coli and its spheroplasts and the protoplasts of gram positive bacteria. | | 1968 | 4973618 |
| nonadaptive growth responses of tetrahymena pyriformis grown on single bacterial species. | | 1967 | 4973773 |
| the n-oxides of some sulfonamide compounds. | | 1968 | 4974587 |
| taxonomic studies on the strain streptomyces thermoviolaceus wr-141. | | 1969 | 4974983 |
| [biologically active metabolites of benzylpenicillin observed in guinea pigs]. | | 1968 | 4976624 |
| [formation of 2 anthracycline antibiotics by the culture related to act. galilaeus]. | | 1968 | 4976627 |
| motility tracks: technique for quantitative study of bacterial movement. | a method for recording movements of bacteria in time and space on a single photograph is described. quantitative information on the behavior of various motile organisms may easily be obtained for comparative studies. the method possesses certain advantages over cinematography, and illustrations of applications of the technique are presented. | 1969 | 4977222 |