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[ultrasonic disintegration method study of the antigens obtained from chlamydia in cross cft]. 1978723661
examination of men with nongonococcal urethritis and their sexual partners for chlamydia trachomatis and ureaplasma urealyticum.chlamydia trachomatis was recovered from 39 (52%) of 75 men who had nongonococcal urethritis and from 28 (37%) of their sexual partners. of the partners of men with chlamydia-positive nongonococcal urethritis, 64% excreted chlamydia, compared with 8% of the partners of men with chlamydia-negative nongonococcal urethritis. in contrast, an apparently sexual mode of transmission was not observed with ureaplasma urealyticum. rates of recovery of u. urealyticum from men with nongonococcal urethritis ...1978725708
[isolation of chlamydia in keratoconjunctivitis].two isolates, identified as chlamydia (neorickettsia) were obtained from the lacrimal secretion of calves with an acute infection on two of a total of four investigated farms with a record of infectious keratoconjunctivitis. in about 70% of the calves that survived there were complement-fixing antibodies against the neorickettsial antigen, the titers ranging from 1:8 to 1:64. calves that yielded the causative agent were investigated in terms of the antibody dynamics. in the remaining herds no sp ...1978726244
response of c3h/hej and c3h/hen mice and their peritoneal macrophages to the toxicity of chlamydia psittaci elementary bodies.intravenous injection of toxic doses of chlamydia psittaci elementary bodies into endotoxin-responsive c3h/hen mice or endotoxin-nonresponsive c3h/hej mice resulted in essentially identical time intervals to death. inoculation of monolayer cultures of thioglycolate-stimulated peritoneal macrophages from the two strains of mice with 250 elementary bodies per macrophage resulted in immediate host cell toxicity, although the c3h/hej macrophages were somewhat less sensitive to elementary body toxici ...1978730377
use of enteric vaccines in protection against chlamydial infections of the genital tract and the eye of guinea pigs.guinea pigs in a test group were fed living guinea pig inclusion conjunctivitis (gpic) organisms classified as chlamydia psittaci in 60% yolk-sac suspensions as enteric vaccines, while animals in a control group received uninfected yolk sac. seven test animals and 14 control animals were challenged 11 or 22 days later with 1,000 50% infectious doses of gpic organisms in either the conjunctiva or the vagina. evidence of protection from mucosal infection in both sites was noted in test animals. cl ...1978739153
[ocular pathology in northern africa]. 1978741115
experimental infection of the chimpanzee urethra and pharynx with chlamydia trachomatis.an isolate of chlamydia trachomatis obtained from a man with nongonococcal urethritis was used to produce experimental urethral and pharyngeal infections in chimpanzees. after urethral inoculation of 8 x 10(1) inclusion-forming units (ifu), infections were established in three of three animals; urethral discharges developed in two. the infections persisted for five to nine weeks. larger inocular (7 x 10(2) and 1 x 10(5) ifu) produced pharyngeal infections in two animals. the third animal's phary ...1978741332
etiologies of postgonococcal urethritis in homosexual and heterosexual men: roles of chlamydia trachomatis and ureaplasma urealyticum.before treatment for urethral gonorrhea, chlamydia trachomatis was isolated from 18% and ureaplasma urealyticum from 37% of 121 men. c. trachomatis was recovered from none of 18 homosexual men who had gonorrhea and from 22 of 95 heterosexual men who had gonorrhea (p less than 0.05). after treatment with a penicillin, postgonococcal urethritis occurred significantly more often in heterosexual than in homosexual men (p less than 0.002). postgonococcal urethritis developed in all men from whom c. t ...1978741335
treatment of chlamydia-positive and chlamydia-negative nonspecific and postgonococcal urethritis.chlamydial and non-chlamydial nonspecific or postgonococcal urethritis in 132 men was treated with different regimens of chlortetracycline and doxycycline. chlortetracycline 250 mg four times daily for 12.5-18.5 days given to 70 men resulted in a clinical cure of urethritis in 80% of cases (56/70). there was no difference in the cure rate between chlamydia-positive (40) and chlamydia-negative (30) cases. in no instance was the treatment failure, i.e., re-appearance of urethritis, associated with ...1978742827
chlamydia trachomatis and pneumonia in infants: report of two cases.in two cases of pneumonia associated with chlamydia trachomatis in infants the symptoms began in the second week of life and the illness was severest at 4 weeks of age. both infants were afebrile. one had a history of conjunctivitis. both presented with a characteristic staccato cough and tachypnea but little evidence of peripheral airway obstruction. chest roentgenograms showed interstitial and alveolar pulmonary infiltration in hyperexpanded lungs. the serum igm concentrations were markedly el ...1978743659
chlamydia shedding by four species of wild birds.four wild bird species--great-tailed grackle (cassidix mexicanus), common grackle (quiscalus quiscula), brown-headed cowbird (molothrus ater), and mourning dove (zenaidura macroura)--were either inoculated intratracheally with chlamydia psittaci or exposed indirectly as uninoculated cagemates. shedding of chlamydiae was monitored by inoculating mice with suspensions of material eluted from cloacal swabs collected from all birds, usually at 3-day intervals. sporadic shedding of chlamydiae was dem ...1978749892
[hemolytic anemia associated with monoclonal bence-jones lambda proteinuria and positive serological reaction for infection with chlamydia microorganisms]. 1978752966
[etiopathogenesis of trachoma. classification and observations]. 1977757799
fifteen-month follow-up study of women infected with chlamydia trachomatis. 1979758599
ophthalmia neonatorum due to chlamydia trachomatis: a family problem?the most frequently seen type of infectious ophthalmia neonatorum, inclusion conjunctivitis, is caused by the organism chlamydia trachomatis. this agent is known to be transmitted sexually. until recently, the infections produced by c trachomatis were though to be relatively benign. recent evidence, however, suggests that the organism may produce urethritis and epididymitis in the male; cervicitis, cervical erosions, salpingitis, and puerperal infections in the female; and prematurity and pneumo ...1979759548
chlamydiae, cervicitis, and abnormal papanicolaou smears.cervical abnormalities accompanied by papanicolaou class ii or class iii cytologic results are commonly encountered in gynecologic office practice. chlamydiae are a common cause of genital tract infection, with or without manifest symptoms or signs. an immunofluorescence method was used to determine the presence of antichlamydial antibodies in cervical secretions. eleven of 15 patients in whom such antibodies were found (73.3%) had papanicolaou class ii or class iii smears, in contrast to only 3 ...1979760016
[current venereological problems]. 1979760074
differences in the therapeutic response of chlamydia-positive and chlamydia-negative forms of nongonococcal urethritis. 1976767309
[effectiveness of vaccination against chlamydia abortion in sheep]. 1975773626
laboratory techniques in ocular virology. 1975773878
the prevention of blindness from trachoma. 1975775692
genital chlamydial infections.the isolation of chlamydial trachomatis in sera of patients with gon ococcal urethritis (gu), non-gonococcal urethritis (ngu), post-gonococca l urethritis (pgu) and trachomainclusion conjunctivitis (tric) is discussed. chlamydiae were isolated in 40% of men with ngu, 20-30% with gu and 0-7% of men with symptomatic or microscopic evidence of urethritis. the rates of isolation of chlamydiae in ngu patients were significantly higher than in controls (p less than .001). the sexual tr ansmitabilit ...1976775980
[experimental infection of guinea pigs with clamydia. 2. fluorescent antibody examinations].the direct fluorescent antibody technique was applied to blood smears and organ impression smears from guinea-pigs killed at various times during 13 weeks following nasal infection with a bovine strain of chlamydia. antigen inclusions were demonstrated one hour after infection in blood granulocytes, after 3 hours in most of the organs examined and after 6-12 hours in all the organs. antigen was present throughout the period of observation in blood smears and samples from nasal mucosa, trachea, l ...1975776118
[chlamydia]. 1976776757
some diseases of domestic rabbits encountered in the western cape.the most common disease conditions encountered in domestic rabbits under intensive conditions in the western cape are discussed. chlamydiosis is of paramount importance; it might be the limiting factor in the developing rabbit industry.1976781238
[ultrastructural study of the trachoma infected conjunctiva]. 1975781768
[the lymphocyte transformation test with the bedsonian antigen (bedsonian ltt) in old and recent fiessinger-leroy-reiter syndromes and in ankylsoing spondylarthritis. additional study].the lymphoblastic transformation test in the presence of bedsonian antigen was positive in 72 per cent of the cases confirmed fiessinger-leroy-reiter syndrome, while it was negative in all the controls. this test remains positive over a long period since it was found to be positive in 69.75 per cent of old cases of flr syndrome diagnosed 13-17 years previously. in cases of post-reiter ankylosing spondylarthritis (asp), the bedonian ltt was positive with equal frequency as in cases of flr syndrom ...1976781787
the incidence and aetiology of respiratory tract infections in general practice--with emphasis on mycoplasma pneumoniae.the incidence of respiratory tract infections in patients seeking medical advice at a community care centre (dalby) during 1973 and 1974 was studied. about every third patient seen at this primary health station presented with signs of such infections. in the age groups less than 10, 10-19, 20-39, 40-59 and greater than or equal to 60 years, respiratory tract infections accounted for 65, 45, 32, 18 and 9% of the fotal number of diagnoses made during 1974. the aetiology of acute respiratory tract ...1976783048
simplified serological test for antibodies to chlamydia trachomatis.three-hundred sixty sera from unselected patients attending two london venereal disease clinics were examined by a microimmunofluorescence test. eleven egg-grown serotypes of chlamydia trachomatis and the so-called "fast" strain sa2(f) were used as antigens. of the 360 sera tested, 119 (33%) reacted to a titer of 1:16 or above with at least one antigen. of these positive sera, over 50% cross-reacted with all 12 serotypes, and 95.5% reacted with sa2(f) in addition to other antigenic types. it is ...1976783191
inclusion blennorrhea: a case report.the case described here represents the first laboratory-confirmed case of inclusion blennorrhea at the mayo clinic since laboratory isolation of chlamydia trachomatis was instituted in 1974. treatment with a sulfonamide preparation proved effective. further aspects of the diagnosis and treatment of inclusion blennorrhea are discussed.1976785121
[comparative detection of fluorescent and complement-fixing antibodies in ovine enzootic abortion]. 1976785796
non-specific urethritis. a placebo-controlled trial of minocycline in conjunction with laboratory investigations.the results of a double-blind therapeutic trial on 81 men suffering from non-specific urethritis (nsu) show that minocycline was more effective than a placebo. before treatment chlamydia trachomatis was isolated from 31 per cent. of the men, ureaplasmas from 58 per cent., and mycoplasma hominis from 7-5 per cent. there is evidence that chlamydiae are a cause of urethritis. however, after minocycline therapy improvement in the clinical response of patients from whom only ureaplasmas were isolated ...1976786440
[chlamydia in human and animal pathology]. 1976787728
[contemporary konwledge on chlamydias (author's transl)]. 1976788930
hemolysis-in-gel test for demonstration of chlamydia antibodies.sheep erythrocytes were coated with antigens of a strain of chlamydia trachomatis serotype d. chlamydial antibodies in sera from patients with salpingitis or pneumonia were demonstrated by passive hemolysis in agarose gel.1976791967
pathological and microbiological observations made on spontaneous cases of acute neonatal calf diarrhea.the purpose of this report is to describe clinical signs, gross and microscopic lesions, bacteriological and immunofluorescence observations made on spontaneous cases of acute neonatal calf diarrhea (ncd) in dairy and beef herds. the following diagnostic tools were used: 1) direct smears of intestinal content, 2) escherichia coli counts, 3) aerobic bacterial cultures of the small intestine and other organs (the o serogroup and the enterotoxigenicity of the e. coli isolated was determined), 4) de ...1976793692
[chlamydial infections of man and animals]. 1976795159
[indication of halprowia (chlamydia) antigens by the direct immunoperoxidase method].the authors modified and approbated the direct immunoperoxidase method for the indication in the infected l cells of the halprowia (chlamydia) antigens--etiological agents of trachoma, ocular and urogenital forms of paratrachoma, arthritis, meningopneumonia and enzootic abortion of sheep. different types of localization of the group-specific halprowia antigen were revealed in the cytoplasm of the affected cells by light microscopy; electron microscopy demonstrated localization of this antigen in ...1976797192
[present-day characteristics of diagnosis of trachoma]. 1975798392
observations of the surface projections of infectious small cell of chlamydia psittaci in thin sections. 1976799722
infection with chlamydia group a in men with urethritis due to neisseria gonorrhoeae.men with urethritis due to neisseria gonorrhoeae were treated with gentamicin, which is inactive against chlamydia. urethral specimens were collected before treatment and one and two weeks after treatment and cultured for chlamydia in irradiated mccoy cells. the overall incidence of chlamydial infection was 15 of 44 (34%). all of 15 chlamydia-positive men and 11 of 29 chlamydia-negative men (38%) developed postogonococcal urethritis two weeks after treatment. pre-treatment sera were examined by ...1975804022
biosynthesis of phospholipids and neutral lipids of monkey kidney cells (llc-mk-2) infected with chlamydia trachomatic strain lymphogranuloma venereum (38538).the biosynthesis of phospho-lipids and neutral lipids in normal and monkey kidney cells infected with lymphogranuloma venereum were compared using 14c-acetate and 14-c-serine in pulse-chase experiments. synthesis of phospholipids and nutral glycerolipids were inhibited in infected cells. phosphatidyl ethanolamine (pe) synthesis increased while phosphatidyl choline, phosphatidyl serine and cardiolipin synthesis decreased in infected cells within 36 hr after infection. sphingomyelin syntheisis ...1975804699
studies on immunity to chlamydiosis in birds, with particular reference to turkeys. 1975804837
polymicrobial etiology of acute pelvic inflammatory disease.we studied 204 women with acute pelvic inflammatory disease to delineate further the causes of that illness. gonococci were recovered from 91. gonococcal pili antibody rose or fell significantly in 12 of 18 patients with positive cultures and only two of 19 who had negative cultures and smears for neisseria gonorrhaoea(p smaller than 0.005). n. gonorrhoeae was found in peritoneal exudate from eight of 21 patients with, and none of 33 without, cervical gonococcal infection. among patients with se ...1975806017
preparation of stable sensitized erythrocytes for detection of chlamydial antibodies.sheep erythrocytes were treated with glutaraldehyde before sensitization for the indirect hemagglutination test to assay chlamydial antibodies. this treatment markedly increased stability during storage.1975809464
comparative susceptibility of eleven mammalian cell lines to infection with trachoma organisms.eleven mammalian cell lines, hela 229, hela m, hep-2, ft, bhk-21, vero, mk-2, mpk, l-wo5a2, mccoy, and l-929, were tested for their susceptibility to infection with trachoma strains tw-3 (type c, ocular origin) and uw-5 (type e, genital origin). all the cell layers were pretreated with diethylaminoethyl-dextran before inoculation of the organisms, and the inocula were centrifuged onto the cell layers. hela 229 was found to be the most sensitive to infection as determined by inclusion counts. the ...1975809479
chlamydia trachomatis immunotype j.a new immunotype j is proposed for a group of chlamydia trachomatis strains which are related to trachoma type c in the microimmunofluorescence typing test. ten immunologically identical strains have been identified from four separate areas of the world. the strains were either isolated from the genital tract or from eye infection originating from the genital tract. they grow readily in hela 229 cell culture but poorly in egg culture. whereas two-way cross-reactions were found between types c an ...1975810514
chlamydial infection of the male baboon urethra.two adult male baboons (papio cynocephalus) were infected by urethral catheter with a type d strain of chlamydia trachomatis isolated from a male patient with nongonococcal urethritis. chlamydial organisms were shed from the urethra for about 90 days and serum antibody developed. intraurethral re-inoculation of homologous and heterologous (type i) strains of chalmydia, 4 and 11 months later, resulted in relatively shorter periods of infection of less than 15 days. the antibody titres and type-sp ...1975811318
chlamydial infection of the male urethra.urethral specimens from 477 men were collected with endourethral swabs and examined for chlamydia trachomatis by cell culture on mccoy cells pretreated with idoxuridine. of these men, 141 had gonococcal urethritis, 262 non-gonococcal urethritis (ngu), and 74 showed no evidence of urethritis. of 118 men with heterosexually acquired gonococcal urethritis, thirty (25 per cent.), and of 23 men with homosexually acquired gonococcal urethritis, five (22 per cent.), yielded c. trachomatis from the uret ...1976816416
the lack of effect of ampicillin plus probenecid given for genital infections with neisseria gonorrhoeae on associated infections with chlamydia trachomatis.forty-six men were successfully treated with a single oral dose of ampicillin (2 g) plus probenecid (1 g) for urethral infections with neisseria gonorrhoeae. chlamydia trachomatis was isolated from cultures of cells obtained from 11 of these men both before and after treatment; c. trachomatis was isolated from one man before but not after treatment and from three men after but not before treatment. no isolates were obtained from the remaining 31 men either before or after treatment. of the 15 pa ...1976816978
ophthalmia neonatorum: a chart review.cases of ophthalmia neonatorum diagnosed at grady memorial hospital 1967-1973 were reviewed. of 302 cases 43 could be diagnosed as gonococcal, 86 chlamydial, 3 gonococcal and chlamydial, 31 staphylococcal, and 5 chemical. silver nitrate prophylaxis was routinely employed. gonococcal cases peaked during the third quarter of the year and chlamydial during the fourth quarter. gonococcal cases were associated with a longer duration of ruptured fetal membranes. definitive etiologic diagnosis could no ...1976819900
the owl monkey (aotus trivirgatus) as an animal model in trachoma research.the owl monkey, aotus trivirgatus, in contrast to other species of nonhuman primates, was shown to be susceptable to infection with strains of chlamydia trachomatis. it responded to experimental infection with a severe, acute, inflammatory reaction of short duration. monkeys which recovered from infection were resistant to reinfection for more than 6 months and resistance was not strain specific. eye secretion antibody titers correlated well with resistance to subsequent challenge. these studies ...1976828229
respiratory-tract colonization and a distinctive pneumonia syndrome in infants infected with chlamydia trachomatis.to learn if chlamydia trachomatis causes in young infants a distinctive penumonia characterized by chronic, afebrile course, diffuse lung involvement and elevated serum immunoglobulins g and m, 47 black infants four to 24 weeks of age were examined for nasopharyngeal shedding of c. trachomatis and serum immunofluorescent antibody to lymphogranuloma venereum type i. nasopharyngeal c. trachomatis was found in 18 of 20 with the pneumonia syndrome, two of 15 with various other illnesses and 10 of 12 ...1977831128
[some viral zoonoses transmitted by pets (author's transl)].besides dogs and cats, various other animals are more or less popular as pets in the netherlands. it is importance to the veterinary practitioner to know which diseases may be transmitted to man by these animals. of the viral zoonoses. rabies constitutes a menace to man, in which dogs and, to a less extent, cats supply a link between man and free-living wild animals. another viral zoonosis in which interest was centered in recent years, is lymphocytic choriomeningitis (lcm) caused by a virus whi ...1977831322
[the role of polyfactorial diseases in livestock husbandry in the netherlands today and in the future (author's transl)].the role of polyfactorial infectious diseases has increased as a result of the indstrial scale of livestock farming. industrial livestock husbandry means keeping a single species of animal in large groups, optimum production on rational grounds being a concurrent object. polyfactorial diseases are those diseases which are due to an infectious component and the clinical pictures of which are also determined to a considerable extent by the environment and by the animal itself. the problems associa ...1977835127
the growth of the ewe abortion chlamydial agent in mccoy cell cultures. 1977838901
serologic diagnosis of lymphogranuloma venereum by counterimmunoelectrophoresis with a chlamydia trachomatis protein antigen.previously a protein antigen was identified which was common to members of the species chlamydia trachomatis and to which antibody could be demonstrated in human sera by two-dimensional immunoelectrophoresis. the antigen has been purified by immunoadsorption chromatography, and an exploration undertaken to determine whether the detection of antibody to this antigen by counterimmunoelectrophoresis would be useful for the diagnosis of c. trachomatis infections. antibody was found in 43 of 45 (96%) ...1977839065
nongonococcal urethritis: the role of chlamydia trachomatis. 1977842992
[sero-epidemiologic studies on the presence of chlymydia in domestic and wild animals]. 1977843329
[findings of microorganisms resembling chlamydiae in the urethra of patients with non-specific urethritis (author's transl)]. 1977843965
[bedsonia infection in sheep (so-called virus abortus)]. 1977847735
severe persistent inclusion conjunctivitis in a young child.a 14-month-old girl had inclusion conjunctivitis although there had been no signs or symptoms that required medical attention in her first year. by 2 1/2 years of age, the child had extensive pannus and corneal scarring that severely reduced vision. the infection was caused by a genital strain of chlamydia trachomatis, tric type e, that was probably acquired at birth. although genitally transmitted chlamydial strains normally cause a self-limiting inclusion conjunctivitis in areas where trachoma ...1977848548
symposium on diarrhea. 6. infectious diarrhea.diarrhea may be primarily infectious in origin. causes can be conveniently classified according to the etiologic agent, which may be viral, chlamydial, bacterial, protozoal, helminthic or fungal. the most common type of infectious diarrhea in canada is viral. bacterial infection, particularly staphylococcal and salmonellal, also is relatively common.1977849557
uncertainties in the treatment of chlamydial infections in infants. 1977850530
[seroepidemiological investigations on the prevalence of chlamydial antibodies in the human (author's transl)].1,075 serum samples taken at random from blood donors and 524 samples from patients were investigated with a group-specific antigen for chlamydial antibodies. antibodies were detected in 9.9% of the blood donors and in 25.7% of the patients, with titers from 1:5 to 1:160 in the former group and up to 1:640 in the latter group. in general, patients had significantly higher titers than blood donors. more attention should therefore be paid to the possible role of chlamydia in infections of unknown ...1977852892
comparative recoveries of chlamydia from urethral specimens using glass vials and plastic microtiter plates.urethral specimens known to contain chlamydia were stored at -70 c in transport medium (2sp). for the test, circular glass coverslips were placed in the bottom of each culture vessel (glass shell vials and plastic microtiters plates [5 by 15 cm]) and seeded with mccoy's cells in medium containing 5-iodo-2-deoxyuridine. after 72 hours, cultures were inoculated with the specimens, and after 72 additional hours the monolayers on the coverslips were stained with iodine. of 43 specimens, chlamydia wa ...1977855829
[unusual small forms in the growth cycle of halprowia (chlamydia) and their possible relation to manifestations of l-transformation].the authors carried out a comparative electron-microscopic study of the ultrastructure and the developmental cycle of 15 halprowiae (chlamydiae) strains isolated in different pathology from man and animals. halprowiae were cultivated in the yolk sac epithelium of the developing chick embryos and in the l-cell monolayer cultures without any special action of the antibiotics and medicines. formation of minute round structures ("minute forms"), 50--120 nm in diameter, separating from the protoplast ...1977857520
chlamydial infection of the urogenital tract in promiscuous and non-promiscuous women.chlamydia trachomatis infection of the urogenital tract of women presumed to be non-promiscuous, and in presumably promiscuous women attending a special clinic in manchester was studied. two hundred female members of hospital staff, who formed the non-promiscuous group, were found to have a 1% incidence of chlamydial infection. this compared with an incidence of 26% among 200 women attending the clinic. among the clinic patients, chlamydial infection was significantly linked with the presence of ...1977858067
cytology of normal and inflamed conjunctivas in dogs and cats.conjunctival scrapings from normal dogs and cats were compared with conjunctival scrapings from dogs and cats with conjunctivitis. normal scrapings usually contained sheets of epithelial cells and small numbers of bacteria. goblet cells were not seen unless the scraping was made from the fornix. in the absence of other signs of ocular disease, an occasional leukocyte was considered normal. the changes in scrapings from inflamed conjunctivas included increased numbers of degenerating epithelial c ...1977858688
chilamydia trachomatis infection in patients with acute salpingitis.we examined the prevalence of chlamydia trachomatis in the cervix and the fallopian tubes of patients with acute salpingitis. cycloheximide-treated mccoy cells were used as the growth medium. for purposes of comparison, women with infections confined to the lower genital tract and women without signs of genital infections were also studied. c. trachomatis was isolated from the cervix in 19 of 53 patients with acute salpingitis, in one of 18 lower-genital-tract infections and in none of 12 withou ...1977859544
an epizootic of pneumonia in captive bighorn sheep infected with muellerius sp.an epizootic of pneumonia in 20 captive rocky mountain bighorn sheep (ovis canadensis) is described. the sheep were maintained in large paddocks for about 9 months after which, in the late summer, the entire herd died within a three week period. large numbers of muellerius adults, eggs and larvae were in the lungs of all sheep. first stage larvae were widely disseminated throughout the lungs and apparently elicited a granulomatous pneumonia. pasteurella sp. and other bacteria were isolated from ...1977864843
the etiology of nongonococcal urethritis in men attending a venereal disease clinic.nongonococcal urethritis was identified as a major reason that men attended our venereal disease clinic. the prevalence of several agents that might cause nongonococcal urethritis was determined. attempts were made to isolate gonococci; chlamydiae, ureaplasms urealyticum, trichmonads, candida sp., and corynebacterium vaginale from urethral swabs from 307 men. chlamydiae were recovered from 31% of the 67 men with nongonococcal urethritis compared to only 4% of 86 asymptomatic men without pyuria. ...1977867205
chlamydial infections in mammals. 1977867743
isolation of chlamydia trachomatis from the male urethra.chlamydia trachomatis was isolated from 26% of urethral swabs taken from 509 men with urethritis. the highest yield of 68% was obtained from a selected group of men with nonspecific urethritis (nsu) who had a frank urethral discharge. this is a higher than in previous reports, and is significantly higher than the isolation of c. trachomatis from men with less severe urethritis. the higher yield was similar to c. trachomatis isolation rates reported among patients with severe trachoma in hyperend ...1977870145
neonatal conjunctivitis caused by neisseria gonorrhoeae and chlamydia trachomatis.in a selected group of 103 babies referred with neonatal conjunctivitis neisseria gonorrhoeae was isolated from 11 and chlamydia trachomatis from 33. concurrent infection was present in three. on toddler sibling developed chlamydial conjunctivitis. after treatment c. trachomatis was re-isolated from six babies during the follow-up period. the discharge started one to three days after delivery in only three babies with gonococcal conjunctivitis and at five to eight days in eight babies. one baby ...1977871893
urethritis due to chlamydia trachomatis.ninety-five men suffering from gonococcal urethritis were treated and observed. forty-nine developed postgonococcal non-specific urethritis (pgu). seventeen men were demonstrated to be free from pgu after careful observation; these formed a control group. chlamydia trachomatis was isolated from urethral material from 26 (53%) of the pgu group but from none of the controls. this difference was highly significant (p less than 0-001). it confirms that c. tachomatis is a pathogen in the urethra. the ...1977871894
isolation of chlamydia trachomatis from throat and rectum of homosexual men. 1977871895
chlamydial infection in neonates. 1977876336
ophthalmia neonatorum associated with maternal chlamydial infections.an unselected sample of 142 pregnant women had a single cervical culture for c trachomatis at 36 to 40 weeks' gestation. of these women, 18 (12.7%) had positive cultures, and their infants were followed in postoperative fashion. of these 18 infants, eight (44%) developed ophthalmia neonatorum. a combination of cultures and conjunctival smears for giemsa staining and fluorescent-antibody examination for infected cells confirmed the diagnosis in 70% of the infants with conjunctivitis. however, 12 ...1977878139
antimicrobial activity of several antibiotics and a sulfonamide against chlamydia trachomatis organisms in cell culture.minimum inhibitory concentrations of several antibiotics and a sulfonamide for growth of the 15 known immunotypes of chlamydia trachomatis were determined in hela 229 cell cultures. the concentrations for complete inhibition of infectious-organism production were (per milliliter): tetracycline, 0.02 to 0.5 mug; rosamicin, 0.05 to 0.25 mug; erythromycin, 0.1 to 0.5 mug; chloramphenicol, 10 mug; penicillin, 0.02 to 50 u; ampicillin, 0.1 to 50 mug; and sulfisoxazole, 2 to 200 mug. the same concentr ...1977883821
survival of chlamydiae after cooling to -196 degrees c.factors influencing the survival of chlamydiae after freezing were reexamined. from the data presented, it is suggested that preservation of laboratory-grown chlamydiae is best achieved through the use of sucrose as the cryoprotective agent, in the presence of 10% serum. dimethyl sulfoxide and glycerol are more toxic. the period of exposure to sucrose before freezing must be kept as short as possible and be at 4 degrees c rather than at room temperature. the rate of cooling during freezing in su ...1977886008
[sensitivity of diploid cell strains to chlamydia]. 1977888332
endocarditis as a manifestation of chlamydia b infection (psittacosis).a case of chlamydia b (psittacosis) endocarditis is described in a patient with no known previous valve disease. after mitral valve replacement a fall in chlamydia b antibody titre occurred. at repeat mitral valve replacement five months later for a paravalve leak no evidence of continuing endocarditis was present. direct confirmation of infection in the patient's apparently healthy budgerigar was obtained. aspects of the pathogenesis, diagnosis, and treatment are discussed.1977901690
treatment of patients suffering from chlamydial infections. 1977903318
the inactivation of chlamydia trachomatis by chlorhexidine ('hibitane'). 1977903334
tetracyclines, chloramphenicol, erythromycin, and clindamycin.tetracyclines are active in vitro against most urinary tract pathogens, chlamydia, mycoplasma pneumoniae, brucella, rickettsiae, and nocardia. chloramphenicol is used primarily for anaerobic infections, haemophilus influenzae meningitis, and infections due to salmonella typhi. erythromycin is active in vitro against m. pneumoniae, streptococcus pneumoniae, and group a beta-hemolytic streptococci. erythromycin may be used as prophylactic therapy for subacute bacterial endocarditis and for recurre ...1977909315
comment on silver nitrate prophylaxis. 1977917663
[chlamydial urethritis (author's transl)]. 1977918002
[role of chylamydia in the pathology of pregnancy and chronic gynecological diseases].for the elucidation of the role of chlamydial infection in pathological pregnancies, serological examination by the cft with group-specific and species ornithosis antigen was carried out on 723 blood serum specimens from women with obstetrical pathology, 124 specimens from patients with various chronic gynecological diseases and 124 control blood serum specimens from women with nromal pregnancy and favourable obstetrical anamnesis. the complement-fixing antibody (cf) was detected in 72 (9.9%) se ...1977919504
vaccination against feline pneumonitis.a commercially available modified live chlamydial vaccine against feline pneumonitis was tested in 26 cats for its ability to protect against aerosol challenge exposure to the feline pneumonitis strain of chlamydia psittaci. after cats were challenge exposed (30 days after vaccination), pyrexia of greater than 40.0 c occurred in 81% of nonvaccinated (control) cats and in 13% of vaccinated cats (principals). evidence of upper respiratory tract disease and the presence of the agent in ocular fluid ...1977921030
limited survey of genital infection by guinea pig inclusion conjunctivitis agent.cervical or urethral scrapings were collected from 245 guinea pigs that had clinical signs of guinea pig inclusion conjunctivitis (gpic) or were parents of newborn young having clinical signs of gpic. giemsa-stained smears were examined for cytoplasmic inclusion bodies, and samples were passaged in 6-day-old embryonating eggs. complement-fixation tests were performed on 44 samples passaged through eggs in an effort to detect the presence of gpic antigen. unequivocal evidence of chlamydial infect ...1977921034
[irradiated cell cultures applied to group a "chlamydiae" isolation (author's transl)].the irradiated mc coy cell cultures method modified by darougar et al. has been used to investigate the frequency of chlamydiae in non-specific genital tract disease, in reiter's disease and in patients suffering from conjonctivits associated with non-specific urethritis. isolates were obtained from 104 men of the 660 suffering from acute urethritis, and from 18 men of the 67 suffering from conjonctivitis associated with urethritis. fourteen female sexual contacts of these men were tested: chlam ...1977921141
[treatment of chlamydial urethro-adnexitis with erythromycin].besides mycoplasmas and ureaplasmas chlamydias are able to cause an urethro-adnexitis in men. jeasts, trichomonas and herpes-viruses are in our patients of less importance. therapy with erythromycine of chlamydial urethroadnexitis is successful.1977924327
toxicity of low and moderate multiplicities of chlamydia psittaci for mouse fibroblasts (l cells).when mouse fibroblasts (l cells) were infected in suspension or in monolayer with 10 to 100 50% infectious doses (id(50)) of chlamydia psittaci (6bc) per host cell, they showed signs of damage 24 to 48 h later. host-cell injuries were termed multiplication dependent when both the ingestion and subsequent reproduction of c. psittaci were required; when only ingestion but not replication was needed, the injuries were considered to be multiplication independent. the time that the injury was first a ...1977924681
bacteriology of the urethra in normal men and men with nongonococcal urethritis.sixty-nine caucasian males without a previous history of urethritis and who developed nongonococcal urethritis (ngu) and 39 similar men without urethritis (nu) were cultured from the urethra for chlamydia trachomatis, mycoplasma hominis, ureaplasma urealyticum, aerobes, and anaerobes. c. trachomatis infection was proven by culture of serology in 26 (38%) of the ngu group and 1 (3%) of the nu group; the c. trachomatis-negative ngu group had significantly more u. urealyticum (81%) than the c. trac ...1977925148
[characteristics of chlamydia]. 1977926365
[chlamydia and psittacosis--clinical studies]. 1977926375
the expanding clinical spectrum of infections with chlamydia trachomatis. 1977929347
antibiotic susceptibility of chlamydia trachomatis.the antibiotic susceptibility of chlamydia trachomatis isolates was determined in a tissue culture system. representatives of all currently recognized serotypes of trachoma-inclusion conjunctivitis agents were tested. tetracycline and erythromycin yielded similar results, with 1.0 mug/ml preventing chlamydial replication. rifampin was the most active antibiotic, with 0.25 mug/ml completely suppressing inclusion formation of all strains. fifty percent end points were usually achieved at one-fourt ...1977931365
a method for testing the antibiotic susceptibility of chlamydia trachomatis in a cell culture system. 1976931835
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