| histopathological studies on experimental yersinia enterocolitica infection in animals. | experiments were made using mice, rabbits, and monkeys. mice were divided into 2 groups: an intravenously injected group and an orally administered one. in either group, lesions were found mainly in mucous membranes on peyer's patches of intestines. lesions consisted of formation of bacterial colonies accompained by accumulation of neutrophils and histiocytes, and proliferation of reticulum cells. severe intestinal lesions were common to the 3 animals. apart from the intestines, the liver showed ... | 1979 | 119611 |
| the relationship between the protective and cross-reacting antigens of brucella spp., yersinia enterocolitica 0:9 and salmonella serotypes of kauffmann-white group n. | vaccination with killed cells of brucella abortus, yersinia enterocolitica 0:9 and salmonella neusdorf evoked cross-reacting antibodies in guinea pigs but only the homologous antigen effectively produced protective immunity to br. abortus. none of these preparations induced protective immunity to y. enterocolitica in gerbils but all stimulated protective immunity to s. landau in balb/c mice. the antigenic determinants responsible for protective immunity to salmonella infection were located on th ... | 1979 | 119612 |
| antigenicity of protein and lipopolysaccharide from yersinia enterocolitica. | the rabbits infected intravenously with viable yersinia enterocolitica (y.e.) produced the precipitating antibodies against a protein component as well as lipopolysaccharide of the organism. the production of the precipitins against protein antigen persisted for a long period of time even after the o-agglutinins had disappeared. the rabbits infected orally with the organism produced only the precipitins against protein antigen, and the amount of the antibody was equal to or greater than that of ... | 1979 | 119613 |
| experimental endocarditis in rabbits. 3. significance of the proteolytic capacity of the infecting strains of streptococcus faecalis. | insertion of a polyethylene catheter into the left ventricle of the heart was used for regular establishment of sterile endocarditis, and bacterial endocarditis was established by injection of approximately 10(8) streptococcus faecalis into the blood stream at the same time as removal of the catheter which had been in place for 3 days. 100 out of 102 rabbits died spontaneously of bacterial endocarditis. evidence is produced that the host-parasite interaction is influenced by the proteolytic prop ... | 1979 | 120105 |
| ["in vitro" activity of a new cephalosporin (cgp-7174-e or cefsulodin) against "pseudomonas aeruginosa" (author's transl)]. | the minimal inhibitory concentration (mic) of four betalactamins (carbenicillin, ticarcillin, piperacillin and (cgp-7174-e) against 109 clinical isolates of pseudomonas aeruginosa was determined by an agar dilution method. cgp-7174-e was the most active (mic 3.4 micrograms/ml), followed in descending order by piperacillin (mic 4.9 micrograms/ml), ticarcillin (mic 22 micrograms/ml) and carbenicillin (mic 36 microgram/ml). high correlation was found between the mic of these betalactamins (r greate ... | 1979 | 120122 |
| experimental studies on the serological relationships between yersinia enterocolitica and brucella abortus. | yersinia enterocolitica o9 was shown to provoke o, oh and h antibody response in calves. brucella abortus failed to generate yersinia h antibody response and generated brucella o antibodies that cross-reacted with yersinia o and oh antigens. the presence of yersinia h agglutinins along with a higher titre of yersinia oh antibody than brucella o antibody is suggestive of subclinical infection with yersiniosis rather than brucellosis. cross-absorption of sera from calves with established yersinia ... | 1979 | 120574 |
| annotations on the measurement of liver ferritin, especially in the rat. | | 1979 | 120687 |
| [oculomotor reflex evoked by vibrassae stimulation in the cat]. | the oculomotor effects of vibrissae stimulation have been studied in the "encéphale isolé" non-anaesthetized cat. intracellular recording of lateral rectus motoneurones showed an excitatory projection via the ipsilateral infraorbital nerve to these motoneurones. the afferent fibers are type a alpha, recuited with a low threshold (0.2-0.5 ma) and convey information about vibrissae displacement. | 1979 | 120789 |
| a simple technique to differentiate between animals infected with yersinia enterocolitica ix and those infected with brucella abortus. | while both brucella abortus and yersinia enterocolitica ix have o antigens in common, they differ significantly with respect to motility. thus br abortus is always non-motile while y enterocolitica is motile when grown at room temperature. the presence of yersinia h agglutinins in serum can be shown to be evidence of previous exposure to y enterocolitica. these agglutinins are not generated by brucella infection. a rapid h agglutination test will serve to provide this differentiation without int ... | 1979 | 122268 |
| unconjugated steroids in the human endometrium. | | 1975 | 122923 |
| inhibitory effect of normal mammalian sera on the rosette formation of human lymphocytes with sheep red blood cells. | | 1975 | 123840 |
| effect of phospholipase a on active transport of amino acids with membrane vesicles of mycobacterium phlei. | active transport of proline remained unaffected in phospholipase a-treated electron transport particles from mycobacterium phlei. however, the steady state level of proline was reduced 50 to 60% in phospholipase a-treated depleted electron transport particles that were devoid of membrane-bound coupling factor-latent atpase activity. the decrease in the uptake of proline in the phospholipase a-treated depleted electron transport particles was not due to a change in the apparent k-m for proline, b ... | 1975 | 123919 |
| evidence that the deferential vein acts as a local transport system for androgen in the rat and the dog. | ligation of the deferential vein of the rat has been shown to bring about a reduction in the androgen-dependent activity of the prostatic rna polymerase enzyme. in the dog, the content of androgens in this vein is of the order of that found in the testicular vein and many times higher than that of peripheral plasma. it seems that the cauda epididymidis alone is sufficient to maintain the ipsilateral lobes of the prostate and seminal vesicles providing an intact ductus deferens and contralateral ... | 1975 | 123961 |
| the microbiological and parasitological colonisation of specified-pathogen-free mice maintained in a conventional animal house. | 2 groups of 44 specified-pathogen-free (spf) mice, caged in groups of 4, were housed at weaning either in isolation in a building housing conventionally-reared animals, or in contact with those animals. 4 mice from each group were examined for microbiological flora and 4 for parasites at intervals for up to 90 days after transfer. proscribed bacteria were isolated from the "in contact' group after 42 days and endoparasites were observed by 16 days and thereafter. no proscribed bacteria were isol ... | 1975 | 124799 |
| possible serotonergic mediation of tonic immobility: effects of morphine and serotonin blockade. | small doses of morphine, within the range of 0.02 mg/kg to 10.15 mg/kg were administered to chickens (gallus gallus) and the effect on the fear-based tonic immobility (ti) response determined. all doses at and above 0.13 mg/kg enhanced the ti response significantly above the levels produced for the 0.2 mg/kg dose and the distilled water control group. administration of a single large dose of p-chlorophenylalanine prevented the morphine-induced enhancement of ti. it was suggested that serotonin s ... | 1975 | 125432 |
| relationship between ca-atpase activity and subunits of myosin in the myocardium of rats conditioned by swimming. | | 1975 | 125656 |
| interaction of adenine nucleotides with multiple binding sites on beef heart mitochondrial adenosine triphosphatase. | beef heart mitochondrial atpase (f1) contained 2 mol of adp and 1 mol of atp/mol of enzyme, which resisted removal by sephadex chromatography with dilute buffers or repeated precipitation with ammonium sulfate. the native enzyme also contained two apparently equivalent binding sites, which participated in readily reversible binding of adenyl-5'-ylimidodiphosphate (amp-p(nh)p), with a kd of 1.3 mum. the failure of amp-p(nh)p to compete effectively with adp for binding sites on f1 may be related t ... | 1975 | 125756 |
| [observations on the combination of iga-deficiency and extremely low antibody titers against measles (author's transl)]. | | 1975 | 126541 |
| immunochemical studies with synthetic immunogens chemically related to peptidoglycan. | rabbits were immunized with synthetic immunogens hsa-(gly-l-ala-l-ala-d-ala-d-ala)39 and hsa-(gly-gamma-d-glu-l-ala-d-ala-d-ala)40, respectively. antibodies against hsa-(gly-l-ala-l-ala-d-ala-d-ala)39 showed a strong precipitin reaction with the homologous antigen, with hsa-(gly-gamma-d-glu-l-ala-d-ala-d-ala)40 and with solubilized peptidoglycan containing peptide subunits with c-terminal d-alanyl-d-alanine. the albumin-peptide conjugates also cross-reacted with rabbit antisera to streptococcus ... | 1975 | 126550 |
| effect of methysergide, a blocker of serotonin receptors, on plasma prolactin levels in lactating and ovariectomized rats. | the effect of methysergide (mes, 2.5 mg/100 g body wt), a serotonin antagonist, on prolactin release has been studied in lactating and ovariectomized rats. mes caused significant increases in prolactin release in both animals. studies in ovariectomized, hypophysectomized rats indicate that this effect is not due to a decrease in the peripheral metabolism of prolactin. in vitro incubations of anterior pituitary fragments with mes failed to demonstrate any increase in prolactin release, suggesting ... | 1975 | 126860 |
| characterization of 5.8s ribosomal ribonucleic acid in neurospora crassa. | neurospora crassa ribosomes contain a species of ribonucleic acid (rna) of molecular weight 54,000, similar to 5.8s ribosomal rna previously described for other eukaryotic organisms. the 5.8s rna from n. crassa was found to be released by heat treatment at 60 c from 25s ribosomal rna but not from 18s ribosomal rna. the base composition of n. crassa 5.8s rna was similar to that of 5.8s rna from saccharomyces cerevisiae, but differed from animal 5.8s rna. during the course of this study, it was di ... | 1975 | 126993 |
| the role of phospholipid acyl chains in the activation of mitochondrial atpase complex. | 1. the role of length and unsaturation of phospholipid acyl chains in the activation of atpase complex was studied with synthetic phosphatidylcholines and a phospholipid-dependent preparation obtained after cholate-extraction of submitochondrial particles (kagawa, y. and racker, e. (1966) j. biol. chem. 241, 2467--2474). 2. micelle-forming, short-chain phosphatidylcholines produced activation only at critical micellar concentration. the reactivated complex was cold-stable but the oligomycin sens ... | 1975 | 127615 |
| interaction of inhibitors with muscle phosphofructokinase. | the interaction of several inhibitors with muscle phosphofructokinase has been studied by both equilibrium binding measurements and kinetic analysis. at low concentrations of citrate a maximum of 1 mol is bound per mol of enzyme protomer. tight binding requires mgatp and very weak binding is observed in the absence of either magnesium ion or atp. itp at low concentrations cannot replace atp. in the presence of mgatp and at ph 7.0, the dissociation constant for the enzyme-citrate complex is 20 mu ... | 1975 | 127795 |
| human muscle spindles: fine structure of the primary sensory ending. | the primary sensory innervation of muscle spindles obtained by muscle biopsy of normal human volunteers was studied with the light and electron microscopes. the parent ia sensory fibre branched 4-6 times, became unmyelinated for 25-30 mum, then formed sensory terminals on each nuclear bag and chain intrafusal muscle fibre. the first 4--5 mum of the unmyelinated segment is believed to be an encoder zone because the plasmalemma was undercoated by a dense granular layer similar to that under other ... | 1975 | 127831 |
| identification and actions of gastric inhibitory polypeptide. | | 1975 | 128084 |
| [vaccination strategy in influenza]. | the present paper deals with the conditions that influenza vaccines must comply with, their efficiency in terms of the route of administration, the major antigenic changes of influenza viruses, that has to be known from beforehand, a basic problem for the efficient control of a pandemic. vaccination must have in view reduction of the mortality and morbidity rate, a major criterion in establishing a programme for the prevention of influenza by vaccination. | 1975 | 128101 |
| [international activities in 1974 for the characterization of water quality near seacoasts]. | | 1975 | 128122 |
| editorial: subunits of myosin. relations to atpase activity and mechanical function of muscle. | under certain conditions the specific atpase activity of myosin of a given muscle can be altered. the cause of this alteration can only lie in the myosin molecule itself. to produce an enzymatic activity of myosin, an interaction between their light and heavy chains is necessary. however, the specific activity appears to be determined mainly by light chains. hence, one ought also to look for a basis of the changed activity in changes of the subunits of myosin. there are strong indications that t ... | 1975 | 128346 |
| dissociated cultures of newborn mouse brain. i. metabolism of sulfated lipids and mucopolysaccharides. | the metabolism of 35so4-sulfated lipids and mucopolysaccharides was studied in dissociated brain cell cultures from newborn albino mouse brains. the cultures were maintained under an atmosphere of 40% o2 and 5% co2 in apparent good health up to 30 days. early morphological examination of the dissociated cells demonstrated an initial partial reaggregation of the cells, which later settled and became confluent bilayered cultures. cell proliferation measured by dna and protein determination, morpho ... | 1975 | 128706 |
| [pyosurgery departments in a multiprofile pediatric-surgery hospital]. | in the child surgery centre situated in a 9--storied building a special pus department, an isolated operating room and a "pus" unit in the intensive care division were designed for treatment of patients with suppurative-inflammatory diseases. the conducted bacteriological studies of the environmental objects and air made it possible to determine the presence of significant differences in qualitative and quantitative indices of contamination of the "pus" and "pure" departments, "pus" and "pure" u ... | 1975 | 129901 |
| ischemia-induced alterations in myocardial (na+ + k+)-atpase and cardiac glycoside binding. | the effects of ischemia on the canine myocardial (na+ + k+)-atpase complex were examined in terms of alterations in cardiac glycoside binding and enzymatic activity. ability of the myocardial cell to bind tritiated ouabain in vivo was assessed after 1, 2, and 6 h of coronary occlusion followed by 45 min of reperfusion, and correlated with measurements of in vitro (na+ + k+)-atpase activity and in vitro [3h]ouabain binding after similar periods of ischemia. regional blood flow alterations during ... | 1976 | 130383 |
| [spontaneous peripheral proteolysis/1st communication: method and results of clinical examinations (author's transl)]. | with a modificated astrup-fibrin plate-method also an inhibition of proteolysis can be registrated. in various medical areas a spontaneous peripheral proteolysis had been found, especially so in chronical bacterial infections. | 1976 | 132940 |
| the effect of increased brain gaba produced by amino-oxyacetic acid on arousal in rats. | previous work has reported behavioral arousal in the rat to be inversely related to cortical gaba production. therefore the effects of an increase in brain gaba levels, induced by amino-oxyacetic acid, on measures of behavioural arousal such as rearing and ambulation were examined. the increase in gaba was immediately associated with decreased rearing, however the behaviour was later indistinguishable from control values while the levels of brain gaba remained raised. it was suggested that the r ... | 1976 | 134388 |
| allergic reaction to allopurinol with cross-reactivity to oxypurinol. | a 25-year-old white man with gout and nephropathy and with a previous reaction to allopurinol was given a trial dose of oxypurinol. he developed malaise, a generalized erythematous reaction with edema, pruritus, and emesis; this was clinically identical to the reaction he experienced with allopurinol. when the patient's lymphocytes were exposed in vitro to oxypurinol and allopurinol, increased dna synthesis was observed, suggesting an immunologic basis for the reaction. this patient indicates th ... | 1976 | 134655 |
| [study of the threshold dose of penicillin which induces an epileptogenic focus during ontogenesis in the rabbit]. | a local application on the cortex surface of a very small drop of ringer solution containing penicillin was performed to establish the threshold dose required to elicit and epileptogenic focus and consequently the occuring latency of it. threshold doses are small (20 - 60 international units) and show a significant decrease during the maturation of the c.n.s. on the other hand latencies, whatever the animal's age, decrease fairly. the results are confronted to the various supposed modes of actio ... | 1976 | 134784 |
| the acid mucopolysaccharides (glycosaminoglycans) in secondary cultures of embryonic rat fibroblasts. | in secondary cultures of embryonic rat fibroblasts the protein-free acid mucopolysaccharides were separated by cetylpyridinium chloride fractionation and identified afterwards. the following acid mucopolysaccharides were found: hyaluronic acid, chondroitin, 2 heparan sulphate fractions, chondroitin-4-sulphate, chondroitin-6-sulphate, and dermatan sulphate. | 1975 | 134903 |
| [bdellovibrio bacteriovorus as a factor in the self-purification of river water]. | | 1976 | 134929 |
| [on the antibacterial activity, absorption, excretion, distribution and metabolism of spectinomycin (author's transl)]. | | 1976 | 135101 |
| bulbourethral gland infections in mice associated with staphylococcus aureus. | | 1976 | 135128 |
| liver plasma membrane enzyme activities following glutaraldehyde fixation. | the wachstein-meisel atpase histochemical method has been previously used to demonstrate the ultrastructural localization of this enzyme in both whole liver and isolated plasma membranes following fixation in glutaraldehyde. in the present study biochemical assay, of liver plasma membrane enzymes following fixation in cold 2.5% glutaraldehyde showed that approximately 40% of mg2+-atpase, but only 4% of (na+-k+)-atpase activity remained in membranes from either control or anit-treated rats. in ad ... | 1976 | 135243 |
| [tuberculosis in domestic animals and its relationship with human tuberculosis]. | | 1976 | 135254 |
| studies of the histochemistry, ultrastructure, motor innervation, and regeneration of mammalian intrafusal muscle fibres. | | 1976 | 137430 |
| [is there a connection between infection with yersinia enterocolitica and regional enteritis? (preliminary communication) (author's transl)]. | after a brief description of the micro-biological, pathological, anatomical and clinical picture of infections with yersinia enteroclitica, attention is drawn to the striking radiological similarity between three patients with yersinia infection and regional enteritis (crohn's disease). whilst the radiological findings due to yersinia infection usually resemble the group of so-called non-sclerosing ileitis (golden) they occasionally differ from this group and resemble the findings in crohn's dis ... | 1976 | 137848 |
| differentiaton of neuropharmacological actions of apomorphine and d-amphetamine. | the dopaminergic agonists apomorphine and d-amphetamine elicit hyperthermic, hyperkinetic and stereotypic responses in the rabbit. the present investigation compares the influence exerted by various serotonergic antagonists upon these activities. apomorphine-induced hyperthemia was antagonized by p-chlorophenylalanine (pcpa), cyproheptadine and cinanserin and was restored in pcpa-pretreated rabbits by regeneration of central serotonin levels, d-amphetamine-induced hyperthermia was reduced by pcp ... | 1976 | 139615 |
| corticosteroid glaucoma. | the non-depolymerised mucopolysaccharides of the anterior chamber angle can become hydrated. this biological oedema can obstruct the trabcculae, but the physiological liberation of catabolic enzymes from the lysosomes depolymerises the mucopolysaccharides and prevent this obstruction. this is, on the contrary, facilited by the corticosteroids, which reinforce the lysosomal membranes and impede the liberation of the catabolic enzymes. there are clones of goniocytes which are corticosensitive and ... | 1977 | 140355 |
| acid mucopolysaccharides in metal-induced tumor and connective tissue capsules surrounding implants in rats. | | 1975 | 142824 |
| ligand-dependent tryptic inactivation of the ouabain sensitivity of adp-atp exchange catalyzed by canine renal na+, k+-atpase. | | 1977 | 143280 |
| [t-cell subpopulations in mixed lymphocyte cultured. model of t-cell interactions]. | the present studies have shown that two subpopulations of thymus-dependent lymphocytes may act synergisticaly in the mixed lymphocyte reaction (mlr) in the mouse. one subpopulation was well represented in the young adult thymus and the other in lymph nodes. for optimum synergy, both populations must be allogeneic to the stimulator cells. pretreatment of either population with mitomycin-c abolished synergy. in a cinetic study lymph node cells were proliferating before thymus cells. a mixture of t ... | 1977 | 145401 |
| [new methods for clearing salmonella excretors (author's transl)]. | | 1977 | 145559 |
| effect of human immunoglobulin preparations on fc rosette formation between anti-d-coated erythrocytes and lymphocytes. | human immunoglobulin (ig) preparations were tested for their inhibitory effect on fc rosette formation between anti-d-coated human erythrocytes and lymphocytes, as compared to their complement activating capacity. both of the two biological activities ascribed to the sites in the fc portion of the igg molecules were found to be reduced in the pepsin-treated, as well as in the s-sulfonated ig preparations, as compared to the activities of the normal human ig preparation. in the plasmin-treated ig ... | 1978 | 150144 |
| [on the connections between the rami communicantes of the sympathicus and the rami posteriores of the loin nerves (author's transl)]. | the existence of anastomoses between the rami communicantes of the truncus sympathicus and the rami posteriores of the loin nerve in man has been confirmed macroscopically and microscopically in 50% of the cases. this is followed by a discussion of the causality of pains in the loin region. | 1978 | 150806 |
| a cell line derived from bbn (n-butyl-n-[4-hydroxybutyl]-nitrosamine)-induced rat bladder cancer: establishment and scanning electron microscopic cell surface characteristics. | this research was performed to establish a cell line from experimental bladder tumor and to discuss the biological characteristics of the cell line so established. tissue cultures of epithelial cells were derived from a rat bladder cancer induced by bbn. the cells showed loss of contact inhibition and the phenomenon of piling up after several subcultures. colonial cloning was used. the population doubling time of the wild strain and the colonial clones was about 30 h. the chromosomal mode ranged ... | 1978 | 151485 |
| chocolate: a review of published reports of allergic and other deleterious effects, real or presumed. | although there are specific contraindications to the ingestion of chocolate by selected individuals, these do not apply to the general population with a frequency that is suggested by the pervasive mistrust of chocolate. these contraindications and mistrusts are reviewed. | 1978 | 152075 |
| irs, hew threaten triple-a bonds. | | 1978 | 152403 |
| the fourth volhard lecture: cardiovascular structural adaptation; its role in the initiation and maintenance of primary hypertension. | | 1978 | 153216 |
| enhancement by caffeine of neocarzinostatin cytotoxicity in murine leukemia l1210 cells. | posttreatment incubation with nontoxic doses of caffeine resulted in enhancement of cell lethality and inhibition of cell growth in l1210 mouse leukemia cells which had been exposed to a protein antibiotic, neocarzinostatin. in addition, caffeine treatment appeared to inhibit the eventual maturation of newly synthesized dna in l1210 cells following exposure to this antibiotic. these results, indicating the existence of caffeine-sensitive repair in l1210 leukemia cells treated with neocarzinostat ... | 1979 | 154973 |
| patterns of neuromuscular disease. as related to stages of normal embryogenesis in voluntary muscle. | skeletal muscle samples from the upper and lower extremities of 38 human fetuses (6 to 18 weeks' gestation) of both sexes were studied by histologic, histochemical, and electron microscopic methods. ultrastructural morphometry was applied. in the different stages of normal development are found regressive changes, ranging from reversible dystrophic to irreversible necrotic alterations, which are characteristic of either primary myogenic myopathies or primary neurogenic muscle atrophies in older ... | 1979 | 156504 |
| enzymic synthesis of steroid sulphates. xii. isolation of dehydroepiandrosterone sulphotransferase from human adrenals by affinity chromatography. | | 1979 | 156557 |
| [isolation of yersinia enterocolitica from rodents in krasnodar territory]. | | 1979 | 158921 |
| [determination of sero- and biovariants of foreign and soviet strains of yersinia enterocolitica]. | the results of the typing of the biochemical and serological variants of yersinia enterocolitica strains from the ussr (10 strains) and other countries (32 strains) are presented. most of these strains, belonging to biovars 1 and 5, could be determined with the use of the antigenic scheme which was proposed by knapp only for biovars 2, 3 and 4. the strains isolated in leningrad and in the far east were found to belong to serovars 6,30; 7,8; 12,25 and 5b according to the scheme proposed by wauter ... | 1979 | 160171 |
| collagen phagocytosis by stimulated mouse peritoneal macrophages in vitro. | | 1979 | 161578 |
| studies of polyoma virus dna: cleavage map of the polyoma virus genome. | a small-plaque polyoma virus, mpc-1, was isolated from a mouse plasmacytoma. the dna of this polyoma virus was cleaved with a restriction enzyme from haemophilus influenzae (hin d), and the molecular weights of the limit products were analyzed by electrophoresis and electron microscopy. the fragments produced by this enzyme have been ordered by analysis of partial digest products. a physical map of the polyoma virus genome was then constructed. | 1975 | 163343 |
| effect of ouabain and phenobarbital on oxidative metabolic activity associated with spreading cortical depression in cats. | | 1975 | 164264 |
| action of various adenine derivatives on cerebellar purkinje cells. | | 1975 | 164266 |
| oncogenic transformation of murine lymphoid cells by in vitro infection with abelson leukemia virus. | spleen cell cultures stimulated to dna synthesis by antigen or mitogen were infected with abelson virus, a c-type rna virus inducing nonthymic lymphomas in mice. after 3 days the cells were transferred to mice and caused 100 percent incidence of lymphomas in as few as 29 days. that a number of the tumors were of donor origin, as shown by female karyotypes in recipient male mice, indicated that cells infected by virus in vitro were transformed. the process depended upon both virus and stimulation ... | 1975 | 165315 |
| [biochemical characteristics of nucleic acid decomposing enzymes of the epidermis]. | | 1975 | 165330 |
| widespread occurrence of a specific protein in vertebrate tissues and regulation by cyclic amp of its endogenous phosphorylation and dephosphorylation. | a protein whose endogenous phosphorylation and dephosphorylation are affected by camp has been found in the soluble and particulate fractions of all vertebrate tissues studied. this phosphoprotein, which contained a substantial proportion of the radioactive phosphate observed on sds-polyacrylamide gels, was estimated to have an apparent molecular weight of 49,000. in the presence of zn++, camp inhibited the endogenous phosphorylation of this protein (protein 49) in the cytosol and microsomal fra ... | 1975 | 165355 |
| tritium labeling of sialylated glycoprotein hormones. | | 1975 | 165378 |
| inhibition by diphenyleneiodonium and by some of its substituted derivatives of gluconeogenesis in isolated rat hepatocytes. | | 1975 | 165996 |
| the ultrastructure of the sensory end-organs (baroreceptors) in the atrial endocardium of young mini-pigs. | light and electron microscopical studies on pig hearts have confirmed the presence in the right and the left atrial endocardium of distinct circumscribed, unencapsulated end-organs (baroreceptors) associated with 4-9 mum thick nerve fibres. the myelin sheath terminates before the entrance of the nerve into the end-organ. the regular presence of thin axon profiles containing clusters of small agranular vesicles, both around the thick nerve fibre and in the periphery of the end-organs, suggests a ... | 1975 | 166065 |
| the influence of sodium, potassium and lanthanum on amino acid release from spinal-medullary synaptosomes. | | 1975 | 166144 |
| alterations in surface proteins in chicken cells transformed by temperature-sensitive mutants of rous sarcoma virus. | | 1975 | 166490 |
| an ultrastructural approach to the study of endocrine cells in vitro. | | 1975 | 168458 |
| fingerprints of polyoma virus proteins and mouse histones. | | 1975 | 169064 |
| genetics of cell transformation by simian virus 40. | the results described in this paper indicate that the integration of the sv40 genome into human chromosome 7 results in the transformation of the human cells and in the expression of sv40-induced antigens. if integration of the sv40 genome in human chromosomes other than 7 ever occurs, it does not result in cell transformation and the expression of the virus-induced antigens. the expression of the sv40 t antigen in different monkey cells transformed by an adeno 7-sv40 hybrid is also related to a ... | 1975 | 169077 |
| the effect of fasting on tissue cyclic camp and plasma glucagon in the obese hyperglycemic mouse. | the effect of 48 h of fasting in c57b1/6j-ob/ob and +/+ mice on body weight (bw), blood glucose (bg), serum immunreactive insulin (iri), plasma immunoreactive glucagon (irg) and on tissue levels of cyclic adenosine monophosphate (camp) were studied. both groups of mice lost weight and demonstrated a decrease in bg and iri with fasting. however, the bg and iri of the ob/ob animals were initially highter and remained higher than those of the 2% of their initial weight while the +/+ lost 14 %. the ... | 1975 | 170069 |
| the requirement for macrophage-lymphocyte interaction in t lymphocyte proliferation induced by generation of aldehydes on cell membranes. | guinea pig t lymphocyte proliferation induced by sodium periodate (naio4) or neuraminidase-galactose oxidase (ng) occurs when lymphocytes and macrophages are cultured together after treatment of either purified t lymphocytes or macrophages with these agents. regardless of which cell initially bears the modified surface carbohydrate, lymphocyte proliferation requires the presence of viable homologous macrophages and fails to occur when they are replaced with fibroblasts, erythrocytes, l2c leukemi ... | 1975 | 170338 |
| spontaneous interferon production and epstein-barr virus antigen expression in human lymphoid cell lines. | established human lymphoid cell lines, many of which spontaneously produce interferon, differ in the efficiency by which they allow expression of epstein-barr virus (ebv) lytic functions. six ebv carrying lymphoid cell lines, selected to either be extremely susceptible or very refractory to ebv superinfection, were tested for spontaneous interferon production. only the three cell lines which were poorly superinfectable with ebv were found to produce interferon. these same three lines could not b ... | 1975 | 170371 |
| [adenovirus and whooping cough]. | | 1975 | 170653 |
| the effect of hydergine on the enzymes involved in camp turonver in the brain. | | 1975 | 173058 |
| experimental and clinical evaluation of two "atromid-s" analogues in relation to their differential modes of action. | | 1975 | 173146 |
| determination of estrogens in pregnancy urine by hemoagglutination inhibition reaction. | a simple and rapid hemoagglutination inhibition reaction system for the estimation of estrogens in pregnancy urine is described. results obtained by this method showed a good correlation with those measure by a conventional radioimmunoassay method and brown's colorimetric method. ninety-seven pregnancy urine samples from various gestational weeks were subjected to the assay, and the usefulness of this method as a screening test for high-risk pregnancy is discussed. | 1975 | 173188 |
| biochemical and immunological studies of some carcinofetal enzymes. | | 1975 | 173230 |
| carcinofetal human isoferritins. | | 1975 | 173233 |
| evidence for ceruloplasmin as a copper transport protein. | | 1975 | 173340 |
| inositol is the water-soluble product of acetylcholine-stimulated breakdown of phosphatidylinositol in mouse pancreas. | | 1975 | 173344 |
| [incorporation of low molecular sh-containing compounds in nitrosyl complexes of nonheme iron in cell-free and cell preparations]. | it has been shown that the endogenic low molecular sh-containing compounds in non-cellular liver and yeast preparates include in nitrosyl non-haem iron complexes at basic ph and in result of addition of iron salts into these preparates. the content of nitrosyl non-haem complexes with sh-containing low molecular compounds is not more than 0,5-1% of the quantity of identical non-haem iron complexes with rs-groups of proteins. the low content of these complexes appear to be due to as the low conten ... | 1975 | 173411 |
| letter: acute leukemia with burkitt's tumor cells. | | 1975 | 173442 |
| cell shape and membrane changes in the eight-cell mouse embryo: prerequisites for morphogenesis of the blastocyst. | | 1975 | 173595 |
| effect of acute inhibition of adrenocorticotrophin secretion on plasma corticosteroids in the rhesus monkey (macaca mulatta). | the half-life of plasma cortisol in the rhesus monkey (m. mulatta), determined by two methods, was about 130 min and longer than that in man; it was unaffected by administration of dexamethasone. dexamethasone (5 mg, i.v.) immediately inhibited the secretion of acth from the monkey pituitary. the plasma half-life of nh2-terminal immunoreactive acth was found to be about 55 min which was much longer than the biological half-life. the adrenal synthesis of cortisol was inhibited by metyrapone which ... | 1975 | 173773 |
| adrenal autotransplants in sheep: prostaglandin a1 is not steroidogenic. | | 1975 | 173926 |
| sulpiride: a study of the effects on dopamine receptors in rat neostriatum and limbic forebrain. | | 1975 | 173950 |
| stimulatory effect of a serum factor on dna synthesis in isolated hepatoma nuclei. | a serum protein present in normal rat serum and absent from the serum of hepatoma-bearing animals at advanced stages has a stimulatory effect on 3h-thymidine incorporation into hepatoma cells in suspension. liver cells maintained in a similar suspension are not affected by the factor. the stimulation appears to be at the level of chromatin or dna. isolated membrane-denuded nuclei from morris hepatoma 7777 incorporate more 3h-ttp when the factor is present in the incubation mixture. nuclei from h ... | 1975 | 174043 |
| binding of cibacron blue f3ga to proteins containing the dinucleotide fold. | a simple, convenient, and sensitive spectrophotometric procedure is described for quantitative measurement of nucleoside phosphate binding sites constructed by the dinucleotide fold. the procedure involves difference spectral titration of such enzymes with the dye cibacron blue f3ga in a spectral region remote from the intrinsic absorbance of proteins or natural ligands. the titration curves can be analyzed to determine the affinity of nucleoside phosphate binding sites for both the dye and the ... | 1976 | 174104 |
| [comparative immediate results after the use of several lyophilized bcg vaccines]. | a number of 1928 children were vaccinated intradermally with 12 series of bcg vaccine produced by the cantacuzino institute and 2 experimental vaccines, prepared in the same laboratory by the same current technique, i.e. a romanian strain and a french strain, lot 1173 p2. with the experimental vaccines 2 doses were used, with the other vaccines a single standard dose of 0.10 mg. appraisal of tuberculin sensitivity 8-10 weeks after vaccination showed differences in tuberculin duration, varying be ... | 1975 | 174178 |
| [immunologic results obtained with an experimental system oftransplantable colonic tumors. possible applications of these results to human intestinal tumors]. | intestinal cancers, morphologically very close to human colo-rectal adeno-carcinoma, have been induced by dimethylhydrazine in inbred rats. graftable lines have been obtained from 5 primary intestinal tumors, and 3 cell lines have been cultivated from the grafts. this model was used to demonstrate carcinofetal antigen(s) on the surface of the intestinal cancer cells. circulating antibodies against tumor-associated antigen(s) have been found in tumor-bearing rats. cancer enhancement was regularly ... | 1975 | 174767 |
| neoplastic transformation of mouse embryo cells by virus released from tumorigenic mouse cells transformed by avian sarcoma virus b77. | mouse c3h embryo cells were transformed in vitro by avian sarcoma virus bratislava 77 (b77) released scantily from a mouse cell line transformed earlier by the same virus. b77 virus transformed c3h embryo cells contained b77 viral genome and were transplantable into syngeneic as well as allogeneic dba/2j young mice in which autochthonous sarcomas were induced. tumors in both strains of mice were virogenic. the probable reasons for an increased transformation capacity of b77 virus in mammals are ... | 1975 | 175302 |
| heart functional responses to pressure overload in exercised and sedentary rats. | female rats that had been subjected to a moderate treadmill running program were compared with sedentary animals on the basis of heart weight, selected biochemical measurements, and heart function. exercised animals maintained normal growth rate, and cardiac hypertrophy was not present. left ventricular rna, dna, and cytochrome c levels were unchanged. heart functional measurements obtained in situ were similar in sedentary and exercised animals under control conditions. when subjected to sustai ... | 1976 | 175664 |
| contribution to the genetics of serum beta-lipoproteins in man. viii. linkage of the ag h/i locus with the ag x/y, ag a1/d, ag c/g, and ag t/z loci. | | 1975 | 176106 |
| [the effect of multiple injections of acth (alone and combined with sodium ribonucleinate) on incorporation of p32-orthophosphate into the mitochondrial rna of the liver, spleen and heart of white rats]. | | 1976 | 176651 |