| autoradiographic localization in polychaete embryos of tritiated mesulergine, a selective antagonist of serotonin receptors that inhibits early polychaete development. | developing embryos of the polychaete ophryotrochal labronica were exposed to tritiated mesulergine, a selective antagonist of the serotonin receptors 5-ht1c and 5-ht2, that also has significant affinity to dopamine d-2 sites, and the labeling was analyzed by autoradiography. already at the earliest developmental stages (1-4 cells), numerous silver grains visualizing 3h-mesulergine binding sites and possibly also serotonin receptors were recorded over the cytoplasm, mostly in association with dec ... | 2006 | 1525017 |
| amiodarone. the dilemma of hyperthyroxinaemia and the treatment of thyrotoxicosis. | the use of amiodarone, a drug which is prescribed increasingly as an anti-anginal and anti-arrhythmic agent, necessitates a high index of suspicion for the development of thyroid disorders, especially thyrotoxicosis. two cases, which illustrate the diagnostic dilemma of hyperthyroxinaemia and the poor response to antithyroid medication, are described. during amiodarone therapy, the clinical features of thyrotoxicosis may be masked or atypical, and the choice of therapy is complicated by a delaye ... | 2006 | 3923304 |
| amiodarone. the dilemma of hyperthyroxinaemia and the treatment of thyrotoxicosis. | the use of amiodarone, a drug which is prescribed increasingly as an anti-anginal and anti-arrhythmic agent, necessitates a high index of suspicion for the development of thyroid disorders, especially thyrotoxicosis. two cases, which illustrate the diagnostic dilemma of hyperthyroxinaemia and the poor response to antithyroid medication, are described. during amiodarone therapy, the clinical features of thyrotoxicosis may be masked or atypical, and the choice of therapy is complicated by a delaye ... | 2006 | 3923304 |
| serum electrolytes and parathyroid hormone in patients in a coronary care unit. | a prospective study was carried out in 499 patients admitted to a coronary care unit (ccu) in order to evaluate the incidence of clinically significant electrolyte disturbances. low serum potassium values (less than 3.6 mmol l) occurred in 7% of the ccu patients and low serum magnesium values (less than 0.70 mmol l-1) in 6%. few patients had low values of both these ions (1.9%). in 49 patients the contents of these electrolytes in muscle biopsies were similar to the values of control subjects an ... | 2006 | 2563748 |
| re: vasectomy and prostate cancer. | | 2007 | 1951287 |
| warfarin potentiated by proguanil. | | 2007 | 1932962 |
| panel of experts answers common computer questions. | | 2007 | 1802757 |
| [current status of soft implants in cataract surgery]. | | 2008 | 2602895 |
| shaping of simulated root canals in resin blocks using the step-back technique with k-files manipulated in a simple in/out filling motion. | a total of 60 simulated root canals in clear resin blocks of various lengths and degree of curvature were prepared by hand with k-files using a step-back enlargement technique. the instruments were manipulated exclusively with a simple in/out filing or rasping motion with no attempt at rotation or twisting. the preparation technique was assessed by instrumentation time, deformation and fracture of instruments, and loss of working distance. the shape of the prepared canals was assessed by direct ... | 2008 | 2634618 |
| syphilis in a renaissance italian mummy. | | 2008 | 2570298 |
| purification and subunit composition of a cholinergic synaptic vesicle glycoprotein, phosphointermediate-forming atpase. | a glycoprotein atpase in cholinergic synaptic vesicles of torpedo electric organ was solubilized with octa-ethylene glycol dodecyl ether detergent. study of potential stabilizing factors identified crude brain phosphatidylserine, glycerol, dithiothreitol, and protease inhibitors as of value in maintaining activity. the atpase was purified from the solubilized, stabilized material by glycerol density gradient band sedimentation velocity ultracentrifugation, and hydroxylapatite, wheat germ lectin ... | 2008 | 2529350 |
| mitochondria as a feature of smooth muscle differentiation: a study of 70 smooth muscle tumors. | we report that the presence of numerous mitochondria is an ultrastructural feature of smooth muscle neoplasms which is diagnostically useful as a marker for smooth muscle differentiation. the number of mitochondria, as well as the usual features of smooth muscle differentiation, were studied in 70 smooth muscle neoplasms from a variety of body sites. the tumors were sub-classified according to the number of mitochondria (in the majority of the tumor cells) as sparse, moderate, abundant or packed ... | 2008 | 2390757 |
| turning point in the management of pregnancies complicated by diabetes. normoglycemia with self blood glucose monitoring of diet and insulin dosing. | | 2008 | 2268482 |
| do real dos practice manipulation? | | 2008 | 2276931 |
| [cholangiocarcinoma: therapeutic aspects]. | | 2009 | 2853692 |
| [cholangiocarcinoma: therapeutic aspects]. | | 2009 | 2853692 |
| long-latency auditory event related potentials in migraine. | the pathophysiology of migraine and its associated perceptual symptoms remains controversial. we recorded long-latency auditory event related potentials (aeps) in 30 unmedicated patients with common migraine, and compared them to 20 controls. 1,000 and 3,000 hz tones were presented in an 80:20 ratio at 75 db sl. 200 responses were recorded and replicated from cz-a1 + a2, with filter band-pass of 1-100 hz, analysis time of 1,000 ms., and interstimulus interval of 1.1 second. n100, p200, and n200 ... | 2009 | 2714975 |
| alveolar cell carcinoma of the lung: a retrospective analysis of 205 patients. | from 1970 to 1986, survival of 205 patients with alveolar cell carcinoma was retrospectively studied. analysis examined the predictive value of presenting symptoms and diagnostic screening results for pathological stage iii or iv disease (advanced) and survival. the lesion presented as a peripheral mass in 121 patients (59%) and as an infiltrate in 84 (41%). follow-up data were available on 199 patients (97%). variables analyzed included indices of background or risk factors, presenting symptoms ... | 2009 | 2847663 |
| alveolar cell carcinoma of the lung: a retrospective analysis of 205 patients. | from 1970 to 1986, survival of 205 patients with alveolar cell carcinoma was retrospectively studied. analysis examined the predictive value of presenting symptoms and diagnostic screening results for pathological stage iii or iv disease (advanced) and survival. the lesion presented as a peripheral mass in 121 patients (59%) and as an infiltrate in 84 (41%). follow-up data were available on 199 patients (97%). variables analyzed included indices of background or risk factors, presenting symptoms ... | 2009 | 2847663 |
| reticulospinal neurons in lamprey: transmitters, synaptic interactions and their role during locomotion. | | 2009 | 2904246 |
| peptidergic modulation of a neuromuscular junction in aplysia: bioactivity and immunocytochemistry. | three endogenous peptides were assayed for bioactivity at an aplysia neuromuscular junction. evoked contractions were enhanced by phe-met-arg-phe-nh2 (fmrfamide) and suppressed by arginine vasotocin; small cardioactive peptide b (scpb) also enhanced contractions at low concentrations, but caused suppression at higher doses. in accordance with their putative roles as neuromodulators, immunocytochemistry revealed fmrfamide-like and scpb-like fibers on the muscle surface. | 2010 | 3011188 |
| peptidergic modulation of a neuromuscular junction in aplysia: bioactivity and immunocytochemistry. | three endogenous peptides were assayed for bioactivity at an aplysia neuromuscular junction. evoked contractions were enhanced by phe-met-arg-phe-nh2 (fmrfamide) and suppressed by arginine vasotocin; small cardioactive peptide b (scpb) also enhanced contractions at low concentrations, but caused suppression at higher doses. in accordance with their putative roles as neuromodulators, immunocytochemistry revealed fmrfamide-like and scpb-like fibers on the muscle surface. | 2010 | 3011188 |
| working on. | | 2010 | 3347557 |
| murine ly-6 multigene family is located on chromosome 15. | murine ly-6-encoded molecules play an important role in the antigen-independent activation of lymphocytes. we have described the cloning of a cdna encoding the protein component of an ly-6 molecule. hybridization studies indicated that this cdna identified multiple dna fragments on southern blots. the banding pattern exhibits a restriction fragment length polymorphism from mice bearing either the ly-6a or the ly-6b allele. we have employed three independent chromosomal mapping techniques, somati ... | 2010 | 2882510 |
| needle localization of nonpalpable breast lesions with a portable dual-grid compression system. work in progress. | a new device and a geometric algorithm facilitate consistent insertion of a needle tip into nonpalpable breast lesions on a single attempt. with the breast compressed by dual grid plates, two oblique exposures are taken. three intersecting planes through the lesion referenced to the grid markings permit easy determination of the lesion coordinates. in initial trials for preoperative breast lesion localization in 11 patients, the needle tip was within the lesion in nine patients and was within 0. ... | 2010 | 2916022 |
| fatal epidermal necrolysis associated with isoxicam. | | 2010 | 2863517 |
| [swelling of the hands and feet in a case of lepromatous leprosy]. | | 2011 | 3238304 |
| aneurysmal bone cyst of the distal thumb phalanx. a case report and review of the literature. | although aneurysmal bone cysts are a well-known, well described clinical entity, their presence in small bones of the hand are not a common occurrence. only 13 previous cases involving the bones of the hand have been reported in the english literature. of these 13, only seven involved the phalanges and no previous case has been described involving the distal phalanx of the thumb. because these lesions may demonstrate aggressive local biologic behavior, when the diagnosis of aneurysmal bone cyst ... | 2011 | 3290871 |
| [placenta percreta: a danger in pregnancy]. | repeated massive bladder haemorrhages of a patient during the 22nd week of her third pregnancy was treated symptomatically for more than three weeks. the cause of the bleeding could not be found. only the knowledge of the clinical features of a placenta percreta led to the survival of the patient. | 2011 | 3234719 |
| continue the fight. | | 2011 | 3188490 |
| [clinical study of the causes of cardiac insufficiency in 100 patients over 65 years of age]. | | 2011 | 3175152 |
| electrophoretic mobility studies on doxorubicin-resistant and -sensitive murine p388 leukemic cells. | the electrokinetic properties of doxorubicin (dox)-resistant (p388/r) and -sensitive (p388/s) murine leukemic cells were studied in a free-flow electrophoresis (ffe) system. the electrophoretic mobilities (em) of p388/s and p388/r cells were 1.07 and 1.35 x 10(-4) cm2 v-1 s-1, respectively, suggesting a higher net negative charge on the p388/r cells. neuraminidase treatment decreased the em of both the p388/s and p388/r cells by 15-20% but had no effect on cellular doxorubicin retention. total a ... | 2011 | 3163971 |
| median cleft of the upper lip in association with frontonasal meningocele, left aniridia and lenticular opacity. | | 2011 | 3084825 |
| plasma infusion therapy in hemolytic uremic syndrome: is it warranted? | | 2011 | 3153026 |
| [otobasal skull fractures--a catamnestic study]. | | 2012 | 3590850 |
| bulimia nervosa in a male. | | 2012 | 3457584 |
| pan masala--adverse effects. | | 2012 | 3693322 |
| pan masala--adverse effects. | | 2012 | 3693322 |
| [cervix cytology and primary malignancies of the gastrointestinal tract]. | during the cancer check-up of a 46-year-old woman a pap v was diagnosed in the cervical scrapings. the atypical cells of the abrasion specimens from the corpus uteri arouse strong suspicion of malignancy. connected with the clinical data, this finding primarily indicated a metastatic involvement of the inner genitals. this suspicion was confirmed by exploratory surgery laparotomy. a large tumor was found intraoperatively which was occupying the entire stomach. concurrently, a diffuse peritoneal ... | 2012 | 3436510 |
| [abscess of the appendiceal stump]. | | 2012 | 3404883 |
| evaluation of the use of albumin controls in rh phenotyping. | | 2012 | 4204587 |
| [radectomy]. | | 2012 | 3273702 |
| urethroscopy and uroflowmetry in the postoperative follow-up of hypospadias. | | 2012 | 3269134 |
| [catecholamine content in the lacrimal fluid of healthy persons and of glaucoma patients]. | | 2012 | 4408768 |
| overuse injuries. | stress injuries common to running athletes are always associated with a breakdown of the protective mechanisms normally inherent in healthy posture and gait. it is more important to identify and treat these breakdowns of the motor process than the resulting injury itself. simple motor screening of athletes can identify functional abnormalities that lead to stress injuries. this screen includes assessment of flexibility of all major joints, responsiveness of primary postural muscles, posture, bal ... | 2013 | 3893750 |
| posterior cerebral artery stenosis. | we analyzed the clinical features of symptomatic posterior cerebral artery (pca) stenosis in 6 patients selected from 15 patients with angiographically documented pca atherostenosis occurring during a 7-year period. transient ischemic attacks (tias) were the major presentation in 5 patients. a homonymous visual field defect was present in 2 patients. tia symptoms were predominantly visual or sensory, or both. the most common visual symptom was difficulty seeing to one side. one patient saw flash ... | 2013 | 3827217 |
| [the incidence of palmar erythema in patients with alcoholic fatty liver--a comparative study with fatty liver of other origins]. | | 2013 | 3820761 |
| dermatologic radiotherapy. the risk-benefit ratio. | | 2013 | 3789771 |
| an ideal agent for drawover anaesthesia? | | 2013 | 3789382 |
| [immediate and long-term results of endarterectomies in atherosclerotic occlusions of the abdominal aorta and iliac arteries]. | an analysis of the clinical material evidences a sufficiently high efficiency of endarterectomy even in spread occlusions of the aorto-femoral segments of atherosclerotic etiology with the absence of atheromatosis and calcinosis of the arteries. good and satisfactory immediate results were obtained in 89.4% of the patients, long-term results in 52.8% and with regard to reoperations--in 67.5% of the patients. | 2013 | 3672780 |
| a hospital's on-site child care center proves to make business sense. | on-site child care centers in hospitals can improve productivity and reduce absenteeism, tardiness, and turnover. they are also effective recruitment tools and can improve the quality of work performed. | 2013 | 3733441 |
| enrollment update: comparison of fall 1984 and 1985 enrollments in american association of colleges of nursing member schools and with trends in higher education enrollments. | | 2013 | 3633928 |
| outcome of treatment at a psycho-educational day unit for young children. | the outcome of treatment at the psychiatric day centre of the red cross war memorial children's hospital in cape town is described. forty-five children were followed up for 2-6 years after discharge--12 were asymptomatic, 22 moderately improved and 11 unimproved. possible means of improving outcome are discussed. | 2013 | 3672274 |
| [what does family anamnesis contribute in routine medical practice?]. | | 2013 | 3557251 |
| continuing problem in congenital rubella syndrome in southern japan. its outbreak in fukuoka and the surrounding areas after the 1965-1969 and 1975-1977 rubella epidemics. | | 2013 | 3758900 |
| [photoelastic analysis of stress on alveolar bone in the abutment of the fixed bridge under vertical loading]. | | 2013 | 3542798 |
| [the limits of medical recognition and decision (author's transl)]. | | 2014 | 4276934 |
| [death following an accident in groenblad-strandberg syndrome]. | | 2014 | 4248985 |
| epidemiology as a field of practice. | | 2014 | 4369995 |
| effect of condensed phosphates on calcification of chick embryo femurs in tissue culture. | | 2014 | 4288875 |
| effect of condensed phosphates on calcification of chick embryo femurs in tissue culture. | | 2014 | 4288875 |
| congenital nonspherocytic hemolytic anemia due to glucose-6-phosphate dehydrogenase deficiency in a japanese child. clinical and metabolic studies. | | 2014 | 4264123 |
| central projections of the eighth nerve in frogs. | | 2014 | 4116203 |
| [preparation and purification of anti-ferritin, anti-cytochrome b 5 hybrid antibodies]. | | 2014 | 4122927 |
| factors predisposing to exercise-induced late asthmatic responses. | seventeen children developed reproducible early and late asthmatic responses (dual reactions) after cycle ergometer exercise. there was a significant correlation between the magnitude of their early and late reactions, emphasizing the direct relationship of these events. no significant differences were observed in the clinical severity of asthma, diurnal variations in fev1, and extent of the early reaction after exercise between children with dual responses and 19 children with single reactions. ... | 2014 | 3968338 |
| the detection of gastro-esophageal reflux: with special reference to esophageal manometry. | | 2014 | 4278560 |
| an unusual but easily treatable cause of dysphagia and dysarthria complicating stroke. | | 2014 | 3933689 |
| [immunohistochemical studies in lichen ruber]. | | 2015 | 4688963 |
| [spontaneous rupture of the liver during pregnancy]. | | 2015 | 4696947 |
| [spontaneous rupture of the liver during pregnancy]. | | 2015 | 4696947 |
| the diagnosis utility of the qk d interval in thyroid disease. | | 2015 | 4653619 |
| weightless bones. | | 2015 | 4642785 |
| comparison of chlorimipramine and imipramine in ambulatory treatment of depression. | | 2015 | 4571649 |
| drug-induced neutropenia-effects of drugs on granulocyte protein synthesis in vitro. | | 2015 | 4785121 |
| drug-induced neutropenia-effects of drugs on granulocyte protein synthesis in vitro. | | 2015 | 4785121 |
| [myocardial contractility, general aspects]. | | 2015 | 4537808 |
| [carboxypeptidase cn. iii. esterolytic activity (author's transl)]. | | 2015 | 4472558 |
| [methods for the control of triethanolaminobentonite and boric ointment prepared on an emulsified water-soluble base of triethanolaminobentonites]. | | 2015 | 4664852 |
| [electronystagmographic findings in wallenberg's syndrome]. | | 2015 | 4382923 |
| ca2+-induced lateral phase separations in phosphatidic acid-phosphatidylcholine membranes. | | 2015 | 4368475 |
| [clinical study on posttraumatic sequelae of the brain, with special reference to the analysis of cases treated in the department of surgery]. | | 2015 | 4288859 |
| [studies on inclusion compounds. 3. interaction of -schardinger dextrin with pharmaceuticals. 2. investigation of solubilizing and stabilizing effects of barbituric acid derivatives]. | | 2016 | 5063320 |
| [hemorrhage from duodenal diverticuli]. | | 2016 | 4974635 |
| [physician-revolutionary a. t. filatov]. | | 2016 | 4914636 |
| the autonomic nervous system and the peripheral circulation. | | 2016 | 4911050 |
| ebstein's anomaly of the tricuspid valve. translation of original description with comments. | | 2016 | 4880232 |
| a hospital based resuscitation programme. an evaluation of its efficiency. | | 2016 | 4766908 |
| [acute appendicitis]. | | 2016 | 4806689 |
| interleukin-10 induction is an important virulence function of the yersinia pseudotuberculosis type iii effector yopm. | pathogenic yersinia species modulate host immune responses through the activity of a plasmid-encoded type iii secretion system and its associated effector proteins. one effector, yopm, is a leucine-rich-repeat-containing protein that is important for virulence in murine models of yersinia infection. although the mechanism by which yopm promotes virulence is unknown, we previously demonstrated that yopm was required for the induction of high levels of the immunosuppressive cytokine interleukin-10 ... | 2012 | 22547545 |
| physiological levels of glucose induce membrane vesicle secretion and affect the lipid and protein composition of yersinia pestis cell surfaces. | yersinia pestis grown with physiologic glucose increased cell autoaggregation and deposition of extracellular material, including membrane vesicles. membranes were characterized, and glucose had significant effects on protein, lipid, and carbohydrate profiles. these effects were independent of temperature and the biofilm-related locus pgm and were not observed in yersinia pseudotuberculosis. | 2013 | 23686263 |
| hereditary hemochromatosis predisposes mice to yersinia pseudotuberculosis infection even in the absence of the type iii secretion system. | the iron overload disorder hereditary hemochromatosis (hh) predisposes humans to serious disseminated infection with pathogenic yersinia as well as several other pathogens. recently, we showed that the iron-sulfur cluster coordinating transcription factor iscr is required for type iii secretion in y. pseudotuberculosis by direct control of the t3ss master regulator lcrf. in e. coli and yersinia, iscr levels are predicted to be regulated by iron bioavailability, oxygen tension, and oxidative stre ... | 2016 | 27446816 |
| quantification of bacterial indicators and zoonotic pathogens in dairy wastewater ponds. | zoonotic pathogens in land-applied dairy wastewaters are a potential health risk. the occurrence and abundance of 10 pathogens and 3 fecal indicators were determined by quantitative real-time pcr (qpcr) in samples from 30 dairy wastewaters from southern idaho. samples tested positive for campylobacter jejuni, stx(1)- and eaea-positive escherichia coli, listeria monocytogenes, mycobacterium avium subsp. paratuberculosis, and salmonella enterica, with mean recoveries of genomic dna corresponding t ... | 2012 | 22983964 |
| temperature-responsive in vitro rna structurome of yersinia pseudotuberculosis. | rna structures are fundamentally important for rna function. dynamic, condition-dependent structural changes are able to modulate gene expression as shown for riboswitches and rna thermometers. by parallel analysis of rna structures, we mapped the rna structurome of yersinia pseudotuberculosis at three different temperatures. this human pathogen is exquisitely responsive to host body temperature (37 °c), which induces a major metabolic transition. our analysis profiles the structure of more than ... | 2016 | 27298343 |
| evaluation of the role of the opggh operon in yersinia pseudotuberculosis and its deletion during the emergence of yersinia pestis. | the opggh operon encodes glucosyltransferases that synthesize osmoregulated periplasmic glucans (opgs) from udp-glucose, using acyl carrier protein (acp) as a cofactor. opgs are required for motility, biofilm formation, and virulence in various bacteria. opgh also sequesters ftsz in order to regulate cell size according to nutrient availability. yersinia pestis (the agent of flea-borne plague) lost the opggh operon during its emergence from the enteropathogen yersinia pseudotuberculosis. when ex ... | 2015 | 26150539 |
| type vi secretion system transports zn2+ to combat multiple stresses and host immunity. | type vi secretion systems (t6sss) are widespread multi-component machineries that translocate effectors into either eukaryotic or prokaryotic cells, for virulence or for interbacterial competition. herein, we report that the t6ss-4 from yersinia pseudotuberculosis displays an unexpected function in the transportation of zn2+ to combat diverse stresses and host immunity. environmental insults such as oxidative stress induce the expression of t6ss-4 via oxyr, the transcriptional factor that also r ... | 2015 | 26134274 |
| yersinia pseudotuberculosis ip32953 survives and replicates in trophozoites and persists in cysts of acanthamoeba castellanii. | yersinia pseudotuberculosis is a foodborne enteric pathogen that causes a mild self-limiting diarrhea in humans. yersinia pseudotuberculosis is able to persist in soil and water and in association with fresh produce, but the mechanism by which it persists is unknown. it has been shown that y. pseudotuberculosis co-occurs with protozoans in these environments; therefore, this study investigates if bacterivorous free-living amoeba (fla) are able to support persistence of y. pseudotuberculosis. coc ... | 2015 | 26025069 |
| reprogramming of yersinia from virulent to persistent mode revealed by complex in vivo rna-seq analysis. | we recently found that yersinia pseudotuberculosis can be used as a model of persistent bacterial infections. we performed in vivo rna-seq of bacteria in small cecal tissue biopsies at early and persistent stages of infection to determine strategies associated with persistence. comprehensive analysis of mixed rna populations from infected tissues revealed that y. pseudotuberculosis undergoes transcriptional reprogramming with drastic down-regulation of t3ss virulence genes during persistence whe ... | 2015 | 25590628 |
| fast and sensitive detection of enteropathogenic yersinia by immunoassays. | yersinia enterocolitica and yersinia pseudotuberculosis, the two yersinia species that are enteropathogenic for humans, are distributed worldwide and frequently cause diarrhea in inhabitants of temperate and cold countries. y. enterocolitica is a major cause of foodborne disease resulting from consumption of contaminated pork meat and is further associated with substantial economic cost. however, investigation of enteropathogenic yersinia species is infrequently performed routinely in clinical l ... | 2014 | 25355759 |
| genome-wide evaluation of the interplay between caenorhabditis elegans and yersinia pseudotuberculosis during in vivo biofilm formation. | the formation of an incapacitating biofilm on caenorhabditis elegans by yersinia pseudotuberculosis represents a tractable model for investigating the genetic basis for host-pathogen interplay during the biofilm-mediated infection of a living surface. previously we established a role for quorum sensing (qs) and the master motility regulator, flhdc, in biofilm formation by y. pseudotuberculosis on c. elegans. to obtain further genome-wide insights, we used transcriptomic analysis to obtain compar ... | 2014 | 25312958 |
| novel genomic tools for specific and real-time detection of biothreat and frequently encountered foodborne pathogens. | the bacterial genera escherichia, salmonella, shigella, vibrio, yersinia, and francisella include important food safety and biothreat agents. by extensive mining of the whole genome and protein databases of diverse, closely and distantly related bacterial species and strains, we have identified novel genome regions, which we utilized to develop a rapid detection platform for these pathogens. the specific genomic targets we have identified to design the primers in francisella tularensis subsp. tu ... | 2012 | 22488053 |