| management and surgical outcome of suprasellar meningiomas. | the authors analyse 22 cases of suprasellar meningiomas, drawing attention to factors influencing on the surgical outcome. in all but one case, symptomatology began with progressive visual failure in one eye. bilateral anosmia was noted in 4 patients with large tumour. mental disorders were conspicuous in 5 cases and 3 patients suffered from epilepsy. headache was severe in 5 cases. endrocrinological disorders were observed in 3 patients. the sella turcica was of normal shape in all cases. marke ... | 1988 | 3189002 |
| spontaneous peritonitis due to klebsiella oxytoca in a patient with cardiac ascites. | | 1988 | 3189273 |
| in vitro activity of u-76,252 (cs-807), a new oral cephalosporin. | u-76,252 is the prodrug of u-76,253. mics of u-76,253 were 0.015 to 0.06 microgram/ml for greater than or equal to 90% of the strains of streptococcus spp., haemophilus influenzae, and proteus mirabilis; 0.25 to 1 microgram/ml for branhamella catarrhalis, escherichia coli, klebsiella spp., and citrobacter diversus; 1 to 8 micrograms/ml for staphylococcus spp.; and 2 to greater than 16 micrograms/ml for other members of the family enterobacteriaceae and aeromonas hydrophila; for 72% of the latter ... | 1988 | 3190194 |
| synthesis and structure-activity relationships in the cefpirome series. ii. analogues of cefpirome with different 7-heteroarylacetamido and 3'-ammonium substituents. | the synthesis and antibacterial activity in vitro of 7-(2-heteroarylacetamido)-3-[(2,3- cyclopentenopyridinium)methyl]cephalosporins and of some related compounds with different ammonium functions in 3'-position are described. the 7-[5-amino-1,2,4-thiadiazol-3-yl] and the 7-[4-aminopyrimidin-2-yl] analogues of cefpirome and compounds with 3-aliphatic ammoniummethyl functions have excellent antibacterial activity. cephalosporins with different n-heterocycles other than pyridine in 3'-position are ... | 1988 | 3192493 |
| in vitro activities of pd 117,596 and reference antibiotics against 448 clinical bacterial strains. | the in vitro activity of pd 117,596, a new fluoroquinolone antibiotic, was tested against 448 bacterial isolates (15 genera) by agar dilution (inoculum, 10(4) cfu per spot). the activity of pd 117,596 was compared with that of 15 antibiotics against 327 gram-negative strains and with that of 8 other antibiotics against 121 gram-positive strains. pd 117,596 demonstrated the best activity against klebsiella spp., enterobacter spp., acinetobacter spp., serratia marcescens, and branhamella catarrhal ... | 1988 | 3196008 |
| omphalophlebitis and osteomyelitis associated with klebsiella septicemia in a premature foal. | gram-negative neonatal septicemia was diagnosed in a premature standardbred colt. clinical signs included lethargy, weakness, loss of suckle reflex, tachypnea, and injected mucous membranes. sequelae included pneumonia, omphalophlebitis, septic arthritis, and osteomyelitis. prepartum maternal uterine infection, premature delivery, abnormal parturition with premature fetal membrane separation, and failure of passive transfer of colostral immunoglobulins increased the foal's risk for developing se ... | 1988 | 3204051 |
| [clinical laboratory approach for estimating effective administrative dose of cefuzonam. evaluation of disc susceptibility test and its interpretation system]. | in vitro activities of cefuzonam (czon) against 273 clinical isolates were studied through the evaluation of mic's and the results of disc susceptibility test. the mic's were determined using the agar dilution method at an inoculum level of 10(6)cfu/ml. the mic80's of czon against streptococcus pneumoniae, escherichia coli, klebsiella pneumoniae, proteus mirabilis, proteus vulgaris, haemophilus influenzae and citrobacter spp. were less than 0.20 microgram/ml. the mic80's against serratia marcesc ... | 1988 | 3204654 |
| [clinical laboratory approach for estimating effective administrative dose of cefoperazone. evaluation of disc susceptibility test and its interpretation system]. | to interpret of the cefoperazone (cpz) disc susceptibility test, a 4 category system is used in japan, but a 3 category system is used in the u.s.a. and europe. in the 4 category interpretation system of showa cpz disc the following classification is used: ( ) mic less than or equal to 3 micrograms/ml, (++) mic greater than 3 approximately 15 micrograms/ml, (+) mic greater than 15 approximately 60 micrograms/ml, (-) mic greater than 60 micrograms/ml. in the 3 category system the classification u ... | 1988 | 3204655 |
| quantitative study of guinea-pig bronchoalveolar cell population after oral administration of ru 41740 "biostim". | | 1988 | 3207469 |
| primary structure of klebsiella serotype k22 capsular polysaccharide: another glycan containing 4-o-[(s)-1-carboxyethyl]-d-glucuronic acid. | the primary structure of the acidic capsular polysaccharide isolated from klebsiella serotype k22 has been investigated using methylation analysis, hydrolysis, bacteriophage-borne enzyme degradation, and n.m.r. spectroscopy. the repeating unit comprises the chain disaccharide----3)-beta-d-galp-(1----4)-beta-d-glcp-(1---- substituted by 4-o-[(s)-1-carboxyethyl]-beta-d-glcpa-(1----6)-alpha-d-glcp-(1---- at o-4 of the galactose. the galactose carries an o-acetyl group on position 6. | 1988 | 3208247 |
| in vivo antibacterial activity of fk482, a new orally active cephalosporin. | the therapeutic activities of orally administered fk482 were compared with those of reference antibiotics against systemic and local infections with a variety of bacteria in mice and rabbits. in systemic infections in mice, oral fk482 was almost as effective as oral cefaclor (ccl) and more effective than oral cephalexin (cex) against staphylococcus aureus, escherichia coli, klebsiella pneumoniae and proteus mirabilis infections. however, fk482 afforded superior protective activity when given sub ... | 1988 | 3209480 |
| biodegradation of substituted benzenes. | the ability of an association of micro-organisms to degrade a range of substituted aromatic compounds was assessed. compounds were provided as sources of carbon and energy, and degradation rates monitored. the effect of the presence of other aromatic compounds and of rapidly metabolizable substrates was also investigated. the significance of bioaugmentation of waste-treatment processes with such an inoculum is discussed. | 1988 | 3209512 |
| enhanced susceptibility of gram-negative bacteria to phagocytic killing by human polymorphonuclear leucocytes after brief exposure to aztreonam. | brief exposure of escherichia coli, serratia marcescens, klebsiella pneumoniae and salmonella typhimurium to supra-inhibitory concentrations of aztreonam enhanced their susceptibility to phagocytic killing by human polymorphonuclear leucocytes. the effect was independent of the continuous presence of the antibiotic and required the presence of serum opsonins. phagocytic killing of pseudomonas aeruginosa was enhanced by prior exposure to subminimal inhibitory concentrations, and killing, relative ... | 1988 | 3209526 |
| [clinical laboratory approach for estimating effective administrative dose of sulbactam/cefoperazone]. | sulbactam/cefoperazone (sbt/cpz) is a preparation containing cpz and sbt, an inhibitor of beta-lactamases, at the ratio 1:1. the reliability of the sbt/cpz disc susceptibility test in estimating approximate values of mics and the utilization of the test in the evaluation of proper administrative doses were studied using 365 strains of clinical isolates. the antimicrobial activity of sbt/cpz was stronger than that of cpz alone. this increase in the antimicrobial activity due to the addition of sb ... | 1988 | 3210296 |
| [antibacterial activities of monobactams against fresh clinical isolates]. | antibacterial activities of monobactam antibiotics (carumonam (crmn) and aztreonam (azt] against gram-negative bacilli isolated from inpatients in the latter half of 1987 were investigated using penicillin (pc: piperacillin (pipc], cephems (ceps: ceftazidime (caz), cefotaxime (ctx), latamoxef (lmox), cefsulodin (cfs], carbapenem (imipenem (ipm] and pyridonecarboxylic acids (norfloxacin (nflx) and ofloxacin (oflx] as reference antibiotics. a total of 400 strains of 13 species, i.e. escherichia co ... | 1988 | 3210297 |
| bacteriological and clinical evaluation of cefotetan in the treatment of severe infections in hospitalized patients. | the authors studied 302 hospitalized patients, 164 males and 138 females aged 15-88 years (average 66 years), with severe infections. cefotetan was administered to 278 of them at the dose of 1 or 2 g, b.i.d. or a single daily dose i.m. other patients [24] were treated with a continuous intravenous infusion of cefotetan (3 g daily in 5% dextrose). of these patients 121 were treated for urinary tract infections (uti); 114 for respiratory tract infections (rti); 41 for liver biliary duct infections ... | 1988 | 3215108 |
| increase in the number and the phagocytic function of guinea pig pulmonary and peritoneal macrophages following oral administration of ru 41740, a glycoprotein extract from klebsiella pneumoniae. | ru 41740 (biostim) which is a purified glycoprotein extract from klebsiella pneumoniae, is an orally active non-specific immunostimulant. in guinea pigs, 8 days after a 7 days oral administration of ru 41740 (10 or 100 mg/kg/day), an increase in the cell population of the pulmonary and peritoneal cavities was observed, especially in that of the macrophages. ru 41740 also enhanced the phagocytic activity of both the alveolar and peritoneal macrophages, when their chemotactic activity was not sign ... | 1988 | 3215709 |
| [antibacterial activity of gentamicin against clinical isolates in pediatrics]. | antibacterial activity of gentamicin (gm), along with activities of other aminoglycosides and beta-lactams, was studied against clinical isolates collected from pediatric patients during a period of may 1986-april 1987. 1. gm-resistance was noted in 22% of staphylococcus aureus, 6% of proteus vulgaris, 8% of morganella morganii, 40% of providencia spp., 6% of enterobacter spp., 14% of serratia marcescens, and 14% of pseudomonas aeruginosa isolates. no gm-resistance was observed with isolates of ... | 1988 | 3216475 |
| in vitro and in vivo effects produced by the immunomodulating agent ru 41740 on human polymorphonuclear leukocytes in the elderly. | the activity of ru 41740, a glycoprotein extract from klebsiella pneumoniae has been investigated on some polymorphonuclear (pmn) functions. chemotaxis, random migration and oxidative metabolism (assessed by chemiluminescence, o2 consumption and o2- generation) were studied in parallel. pmn were collected from adult and aged human volunteers. experiments were performed either in vitro or in vivo in a double blind placebo assay. in both pmn populations ru 41740 enhanced oxidative metabolism eithe ... | 1988 | 3216720 |
| [recurrent subglottic laryngitis in children with angiomas of the head and neck]. | | 1988 | 3217167 |
| neonatal septicaemia in kelantan, malaysia. | a retrospective study of 84 cases of neonatal septicaemia admitted into a neonatal unit in a rural area of malaysia for 1 year between 1st september 1985 to 31st august 1986 was carried out to determine the spectrum of micro-organisms and predisposing factors in relation to early and late onset septicaemia. the incidence of neonatal septicaemia was 2.13 per 1,000 live-births per year and the case fatality was 41.7% with higher case fatality in those who were premature, those who presented as ear ... | 1988 | 3218934 |
| in vitro activity of cefixime, a new oral cephalosporin. | the in vitro activities of cefixime and seven comparative oral antimicrobials were studied. mic90s of cefixime were 0.015-1 micrograms/ml for haemophilus influenzae, branhamella catarrhalis, escherichia coli, klebsiella, citrobacter diversus, proteus, providencia, aeromonas hydrophila and streptococcus. mic90s for other enterobacteriaceae were greater than or equal to 2 micrograms/ml; 44% of those strains were inhibited by less than or equal 1 microgram/ml. staphylococcus, psuedomonas aeruginosa ... | 1988 | 3219746 |
| therapeutic efficacy of ofloxacin, ciprofloxacin and ny-198 in experimentally infected normal and alloxan-induced diabetic mice. | the therapeutic efficacy of ofloxacin, ciprofloxacin and ny-198 was compared in alloxan-induced diabetic mice with experimental respiratory and urinary tract infections. respiratory infection due to klebsiella pneumoniae dt-s was well controlled by treatment with all compounds tested both in normal and diabetic mice. similar observations were made in a model of urinary tract infection due to serratia marcescens t-55. there was no difference between normal and diabetic mice in therapeutic efficac ... | 1988 | 3219995 |
| human igg and iga subclass response following immunization with a polyvalent klebsiella capsular polysaccharide vaccine. | the human igg and iga response was determined after vaccination with an experimental 24-valent klebsiella capsular polysaccharide vaccine. the majority of natural antibody acquired prior to immunization was found in the igg1, igg2 and iga1 subclasses. the immune response to vaccination was concentrated within the igg1, igg2, iga1 and iga2 subclasses with greater than or equal to 70% of subjects responding with a significant (greater than or equal to fourfold) rise in titer. the igg3 and igg4 res ... | 1988 | 3220104 |
| [clinical research on transfer of cefpiramide to the blood and large intestinal tissue in patients with cancer of the large bowel]. | cefpiramide (cpm) shows antibacterial activity against staphylococci, enterococci, pseudomonas aeruginosa and anaerobic bacteroides spp. cpm is a cephalosporin antibiotic which also exhibits antibacterial activity against klebsiella and intestinal bacteria including escherichia coli. concentrations in blood of cpm which has antibacterial activity against main bacterial species detected during gastrointestinal surgeries and concentration transferred to the large intestinal tissue were measured in ... | 1988 | 3221427 |
| [clinical laboratory approach in estimating the effective dosage of cefamandole]. | reliability of the cefamandole (cmd) disc susceptibility test in estimating approximate values of mics was studied using various clinical isolates totaling 246 strains with showa discs (8 mm diameter containing 30 micrograms of cmd). clinical significance of a 4 category system for the interpretation of the cmd disc tests, which is normally used in japan, was also evaluated to determine whether this system would be suitable or not for the evaluation of a proper dose of administration. the result ... | 1988 | 3221428 |
| survival of coliforms and bacterial pathogens within protozoa during chlorination. | the susceptibility of coliform bacteria and bacterial pathogens to free chlorine residuals was determined before and after incubation with amoebae and ciliate protozoa. viability of bacteria was quantified to determine their resistance to free chlorine residuals when ingested by laboratory strains of acanthamoeba castellanii and tetrahymena pyriformis. cocultures of bacteria and protozoa were incubated to facilitate ingestion of the bacteria and then were chlorinated, neutralized, and sonicated ... | 1988 | 3223766 |
| hyaluronic acid-degrading enzymes in rat alveolar macrophages and in alveolar fluid: stimulation of enzyme activity after oral treatment with the immunomodulator ru 41740. | ru 41740 (biostim) is an immunomodulator clinically used for the treatment of chronic bronchitis and recurrent pulmonary infections. in these diseases large amounts of mucus are produced which congest the bronchi. a major glycosaminoglycan constituent of this mucus is hyaluronic acid, one of the largest molecules in nature; its metabolic degradation is carried out by 3 acid hydrolases: hyaluronidase, beta-n-acetylglucosaminidase, and beta-glucuronidase. in the lung these enzymes are especially s ... | 1988 | 3224214 |
| clinical safety and efficacy of ofloxacin. | in this study we report about the efficacy and tolerability of ofloxacin in the treatment of 15 patients with severe and moderately severe infections including osteomyelitis (5), soft tissue infections (5), salmonellosis in aids patients (2), acute or chronic pulmonary infections (2) and mediastinitis (1). the following organisms were isolated in culture specimens: staphylococcus aureus (4), pseudomonas aeruginosa (4), staphylococcus epidermidis (3), serratia marcescens (1), escherichia coli (1) ... | 1988 | 3224401 |
| incidence of bacteremia in patients with opisthorchiasis during recurrent cholangitis. | a total of 257 haemocultures were performed in 50 patients with opisthorchiasis when they presented signs and symptoms of biliary tract infection. 19 patients showed positive haemoculture. there are no significant relationship between the age of the patient and the incidence of positive haemoculture. septic shock occurred in 5 patients, one patient died. out of 221 aerobic cultures, 14% were positive and of the 36 anaerobic cultures 11% were positive. the most common organism was staphylococcus ... | 1988 | 3227401 |
| [microbiological characteristics and detection of capsular forms of bacteria of the intestinal group in confectionery produced at the candy-chocolate factories]. | five types of confectionery and its semifinished products were investigated for contamination with klebsiella, mesophilic aerobic and elective anaerobic, coliform bacteria, e. coli, etc. after a long-term storage. e. coli and st. aureus were not detected after inoculation on 1 g of the product; mold fungi were identified only in singular samples, their level did not exceed 20 cfu/g; the level of mesophilic aerobic and elective anaerobic bacteria varied from several hundreds to 3000-5500 cfu/g; c ... | 1988 | 3232341 |
| [risk of infection in premature infants with premature rupture of fetal membranes in correlation to respiratory distress syndrome]. | the spectrum of infective agents in 58 preterm deliveries with premature rupture of the membranes (prom) is examinated by assessment of bacteriological swabs. in the earliest weeks of gestation all children had severe rds. nearly 40% of the detected pathogens belonged to the non pathogenic vaginal flora. e. coli, streptococcus species, klebsiella and candida were predominant in the group of facultative pathogenic infective agents. there is an enlarged colonization in maternal swabs after greater ... | 1988 | 3232426 |
| klebsiella spp. in prairie aquifer. | | 1988 | 3233381 |
| studies of metabolites in diarrheal stool specimens positive for klebsiella, serratia, and proteus spp. by frequency-pulsed electron-capture gas chromatography. | diarrheal stools from infants from which klebsiella pneumoniae, serratia liquefaciens, and proteus mirabilis were isolated as possible causative agents of diarrhea were studied. these stools, along with control stool specimens which were collected from infants in the same village of tamooh (near cairo, egypt), were analyzed by frequency-pulsed electron-capture gas chromatography (fpec-gc). watery stools and formed stools, to which distilled water was added, were centrifuged, and the supernatant ... | 1988 | 3235497 |
| enzyme-linked immunosorbent assay to evaluate the immunogenicity of a polyvalent klebsiella capsular polysaccharide vaccine in humans. | a highly sensitive enzyme-linked immunosorbent assay was developed for klebsiella capsular polysaccharide (cps) and used to evaluate the immunoglobulin g (igg) antibody response to a 24-valent cps vaccine in seven adult volunteers. the median rise in titer to all vaccine antigens in samples from the volunteers was significant (twofold or greater). significant igg responses to 11 immunologically related serotypes not included in the vaccine were also noted. the mean cross-reacting igg titer of 12 ... | 1988 | 3235653 |
| [clinico-epidemiological study of 57 cases of bacteremia caused by klebsiella]. | | 1988 | 3236931 |
| the use of purine compounds as sole sources of carbon and nitrogen by klebsiella species. | sixty-one strains of enterobacteriaceae were tested for purine assimilation, including twenty-five klebsiella pneumoniae, seventeen k. oxytoca and nineteen others. only k. pneumoniae and k. oxytoca were able to use guanosine triphosphate, xanthine, hypoxanthine, or uric acid as sole sources of carbon and nitrogen. when guanosine triphosphate was used as sole source of nitrogen and carbon, the lag phase was prolonged. the addition of glucose did not affect the maximum number of viable cells for k ... | 1988 | 3237119 |
| in vitro susceptibility of bacteria to a ticarcillin-clavulanic acid combination. | in vitro testing of bacterial susceptibility to a combination of ticarcillin and clavulanic acid was done, using 406 aerobic gram-positive and gram-negative isolates (considered to be pathogens) cultured from equine and small animal specimens. a microdilution broth technique of susceptibility testing was performed, using trays with wells containing a range of doubling concentrations of dehydrated ticarcillin (range, 0.50 to 128 micrograms/ml) with fixed concentration of clavulanic acid (4 microg ... | 1988 | 3239838 |
| [the structure of capsule polysaccharide of klebsiella ozaenae k4 containing 3-deoxynonulosonic acid]. | 3-deoxy-d-glycero-d-galacto-nonulosonic acid was identified as a component of the klebsiella ozaenae k4 capsular polysaccharide. on the basis of methylation, complete and partial acid hydrolyses, smith degradation, and nmr analysis including computer-assisted 13c nmr evaluation, the following structure of the polysaccharide has been established. | 1988 | 3240330 |
| [excretion of antibiotics into bile and urine in patients with external cholecystostomy done in order to treat obstructive jaundice]. | biliary and urinary concentrations and recoveries of 3 different antibiotics (piperacillin (pipc), cefbuperazone (cbpz) and cefoperazone (cpz], after intravenous bolus injection were studied using the crossover method with external cholecystostomies done in order to treat obstructive jaundice due to complete obstruction of the lower biliary tract; the concentrations of antibiotics in bile and urine were determined by means of a high performance liquid chromatography method. drug concentrations a ... | 1988 | 3241327 |
| [clinical evaluation of s 6472 granule preparation (sustained-release cefaclor) in chronic bronchitis]. | s 6472 granule preparation, a sustained-release cefaclor, was orally administered to 20 acutely exacerbated cases of chronic bronchitis at a daily dosage of 750 mg (titer) in 2 divided doses for a duration of 7-15 days and its clinical usefulness was evaluated. clinical efficacies were good in 17 cases and fair in 3 cases, with a rate of efficacy of 85.0%. organisms isolated from 13 patients were totalling 14 strains, i.e., 5 strains of streptococcus pneumoniae, 3 strains of branhamella catarrha ... | 1988 | 3241328 |
| [epidemiology of bronchopulmonary hospital infections]. | hospital acquired infections (hai) represent one of the major problems, due to their elevated frequency and high number of fatal cases, in the control of infectious diseases. with the perspective to evaluate the incidence of bronchopulmonary infections and to determine their role as cause of death of hospitalized patients, as well as to identify the etiology and the associated risk factors, we have studied 105 autopsy cases of patients decreased in hospital. 37 patients had pneumonias, of which ... | 1988 | 3242560 |
| preparation of branched hexasaccharides by the action of a viral lyase on klebsiella k14 polysaccharide. | klebsiella k14 capsular polysaccharide was degraded by a bacteriophage-borne enzyme to afford oligosaccharides a-c which were studied by one- and two-dimensional n.m.r. spectroscopy. a and b were the repeating-unit hexasaccharide and pyruvylated hexasaccharide, respectively, while c was a dodecasaccharide. each oligomer was terminated by a reducing mannose and a non-reducing 4-deoxy-alpha-l-threo-hex-4-enopyranosyluronic acid residue, indicating that the phage enzyme had cleaved the beta-d-manp- ... | 1988 | 3242801 |
| activity of cefixime (fk 027) for resistant gram-negative bacilli. | cefixime is an orally absorbable cephalosporin with an extended spectrum of in vitro activity for gram-negative bacteria especially members of the enterobacteriaceae. gram-negative rod isolates collected over a three month period were tested against cefixime. greater than 99% of escherichia coli isolates was susceptible to cefixime including those resistant to ampicillin. similarly isolates of klebsiella, proteus and providencia were also exquisitely susceptible to cefixime as were 91% of entero ... | 1988 | 3243091 |
| [rifampicin in the treatment of infections of non-tuberculous etiology]. | clinical efficacy of rifampicin, a semisynthetic broad spectrum antibiotic was estimated in 247 patients with purulent inflammations. it was shown advisable to use rifampicin intravenously in treatment of severe bronchopulmonary pathology, disorders of the bile excretion system, osteomyelitis, severe wound infections and in prophylaxis of postoperative purulent complications in cardiovascular surgery and other cases. high rifampicin sensitivity of staphylococci and streptococci belonging to vari ... | 1988 | 3245710 |
| clinical efficacy of carumonam. | carumonam is a new n-sulfo-beta-lactam antibiotic active against aerobic gram-negative bacteria. an open study was carried out to evaluate the efficacy, safety and tolerance of carumonam with either 1 g t.i.d. (group a) or 2 g t.i.d. (group b) in bacterial septicaemia or severe sepsis. a total of 24 patients (14 men and 10 women) were included in the study, their ages ranged from 48-87 years (mean age 59). eighteen patients were treated for bacteraemia, three for bronchopneumonia, two for urinar ... | 1988 | 3246211 |
| [genetic biochemistry of nitrogen fixation]. | | 1988 | 3249079 |
| [the in vitro activity of ofloxacin, pefloxacin and ciprofloxacin against various gram negative bacteria isolated from urinary tract infections]. | in this study the in vitro activity of ofloxacin, pefloxacin and ciprofloxacin against various gram negative bacteria isolated from urinary tract infections was examined. of 80 isolates (24 e. coli, 10 enterobacter, 10 klebsiella, 23 proteus, 10 pseudomonas, 2 morganella and 1 serratia) 49 were from inpatients, and 31 were from outpatients. ciprofloxacin was the most potent compound and no resistant strain was found against ciprofloxacin, while 1 enterobacter strain and 1 pseudomonas strain were ... | 1988 | 3252111 |
| [causative agents of urinary tract infections and sensitivity to antibiotics]. | our study was done on the outpatients and inpatients of ankara numune hospital who were diagnosed as having urinary tract infections. when 301 cultures with positive results were evaluated. gram-negative bacteria were found most frequently (e. coli 45.2%, klebsiella 23.2%, enterobacter 16.6%, proteus 11.5%, s. aureus 2.2%, pseudomonas 1.3%). by using the disc diffusion method, the effectiveness of antibiotic discs of amikacin, tobramycin, netilmycin, cephoperazone, cephotoxime, cephtizoxime, cep ... | 1988 | 3252113 |
| [a new rapid antibiotic susceptibility test for enteric bacteria using a color change method]. | the rapid antibiotic susceptibility tests that have been developed so far cannot be used in daily work, because of their many difficulties and disadvantages. we have developed a new antibiotic susceptibility test for enteric bacteria which gives the result in 4 hours, easy to perform and inexpensive. this method depends upon the mechanism which detects the acid formed by the bacteria, by the change of the color of the ph indicator in the medium. the susceptibility of 110 different isolates of en ... | 1988 | 3252116 |
| [antibiotic-resistant microorganisms isolated from the urine of patients with suspected urinary tract infections]. | in our study 5331 urine specimen have been examined. in 22 of the total 2 types of bacteria have been isolated and in the cultures of 1167 patients colony counts over than 100.000/ml. have been determined. these are 599 escherichia coli, 161 hemolytic escherichia coli, 104 klebsiella, 93 proteus, 81 pseudomonas, 65 staphylococcus epidermidis, 44 staphylococcus aureus, 24 enterobacter, 18 enterococcus. 602 of the infected patients were women and 565 were men. according to antibiogram results micr ... | 1988 | 3252120 |
| temocillin efficacy in experimental klebsiella pneumoniae meningitis after infusion into rabbit plasma to simulate antibiotic concentrations in human serum. | an infusion system was developed to simulate in the plasma of rabbits the concentrations of temocillin in human serum measured after administration of a 2-g intravenous bolus dose. the efficacy of therapy with this infusion against experimental klebsiella pneumoniae meningitis was compared with that of a conventional bolus dose to the animals. the marked difference between the elimination half-life (t1/2) of temocillin in rabbit plasma and human serum (0.3 and 5 h, respectively) was reflected in ... | 1988 | 3252752 |
| regarding the ankylosing spondylitis/klebsiella/hla-b27 problem: more inconclusive proof! | | 1988 | 3258748 |
| bmy-28100, a new oral cephalosporin: antimicrobial activity against nearly 7,000 recent clinical isolates, comparative potency with other oral agents, and activity against beta-lactamase producing isolates. | the antimicrobial activity of bmy-28100 was tested against approximately 7,000 bacterial pathogens in a multicenter, multiphased collaborative investigation. the bmy-28100 spectrum and antimicrobial potency was most similar to that of cefaclor and superior to that of cephalexin among currently available cephalosporins. species that had greater than or equal to 90% of clinical strains inhibited by bmy-28100 (less than or equal to 8.0 micrograms/ml) were: citrobacter diversus, escherichia coli, kl ... | 1988 | 3259489 |
| in vitro modulation of human monocytes functions by ru 41740 (biostim). | the in vitro effects of ru 41740, a mixture of two glycoproteins extracted from k. pneumoniae and possessing immunomodulatory activity, on human monocyte's cytotoxic activity, migratory capacity and monokine production were investigated. exposure to ru 41740 in nanogram concentrations was associated with rapid increases in il-1 and tnf production and marked augmentation in the monocytes' killing of tnf-sensitive targets, whereas killing of tnf-insensitive targets required longer exposures to mic ... | 1988 | 3259556 |
| antibacterial activity in human urine of fosfomycin trometamol in an in vitro model of the urinary bladder. | the urinary concentrations of fosfomycin trometamol, norfloxacin, pipemidic acid and cotrimoxazole were studied at various times after oral administration of drugs in healthy volunteers. using the same urine, the bactericidal activity of four antimicrobial agents against escherichia coli, proteus mirabilis and klebsiella pneumoniae in an in vitro model simulating the treatment of bacterial cystitis was also evaluated. the results obtained show that very high concentrations of the drugs were achi ... | 1988 | 3259909 |
| treatment of experimental cystitis in the rat with a single dose of fosfomycin trometamol. | the therapeutic effectiveness of a single oral dose (60 and 200 mg/kg body weight) of fosfomycin trometamol (ft), norfloxacin, trimethoprim sulfamethoxazole (bactrim) and pipemidic acid against experimental cystitis in the rat were compared. infections were produced with clinical isolates of klebsiella pneumoniae, proteus mirabilis and escherichia coli in a total of 135 sprague-dawley albino rats. oral treatment with all four drugs consistently lowered the numbers of cfu in bladder tissue, espec ... | 1988 | 3259910 |
| complete amino acid sequence of p453-plasmid-mediated pit-2 beta-lactamase (shv-1). | the complete amino acid sequence of the p453-plasmid-mediated pit-2 beta-lactamase (shv-1) was determined. the protein contains 265 residues. peptides resulting from digestions with trypsin, staphylococcus aureus v8 proteinase, chymotrypsin and lys-c proteinase and cleavage with cnbr were separated and purified by using reverse-phase h.p.l.c. the amino acid sequence of each peptide was manually determined with the dimethylaminoazobenzene isothiocyanate/phenyl isothiocyanate double-coupling metho ... | 1988 | 3260490 |
| in vitro activity of an oral iminomethoxy aminothiazolyl cephalosporin, r-3746. | the in vitro activity of r-3746, an iminomethoxy aminothiazolyl cephalosporin with a ch2och3 moiety at position 3, was compared with those of other antibiotics. r-3746 inhibited the majority of hemolytic streptococci (groups a, b, c, f, and g) and streptococcus pneumoniae at less than 0.06 micrograms/ml, which was comparable to the activity of amoxicillin, 2- to 8-fold more active than cefixime, and 16- to 64-fold more active than cefaclor and cephalexin. ninety percent of beta-lactamase-produci ... | 1988 | 3260766 |
| the treatment of endomyometritis. | the mainstay of treatment for postpartum endometritis is a combination of antibiotics, such as clindamycin plus an aminoglycoside. in an effort to save time and reduce the cost of treating this infection, researchers have investigated monotherapy with a beta-lactam antibiotic. twenty-five patients with postcesarean endometritis and three with postpartum endometritis were studied at two sites for the effectiveness of 3.1 g ticarcillin disodium/clavulanate potassium administered every four or six ... | 1988 | 3260948 |
| respiratory failure in children with acquired immunodeficiency syndrome and acquired immunodeficiency syndrome-related complex. | acute respiratory failure has a high mortality in patients with acquired immunodeficiency syndrome (aids). this study was undertaken to determine the etiology of acute respiratory failure and the outcome of children with aids and aids-related complex. records of 31 children with aids or aids-related complex admitted to the pediatric intensive care unit for acute respiratory failure throughout a 46-month period were reviewed. acute respiratory failure was due to pneumocystis carinii pneumonia in ... | 1988 | 3261005 |
| acute anterior uveitis and faecal carriage of gram-negative bacteria. | in a prospective study a high recovery of faecal klebsiella was obtained in patients with acute anterior uveitis, who bear hla-b27 or other hla-b7 creg antigens. | 1988 | 3261190 |
| anti-klebsiella k30 phospholipid antibodies in systemic lupus erythematosus: antigen cross-reactions and idiotypic sharing with antibodies to dna and klebsiella k30 polysaccharide. | patients with systemic lupus erythematosus were examined for the presence of serum antibodies reactive with phospholipids (pl) extracted from the membranes of klebsiella k30 (k30pl). affinity-purified anti-k30pl antibodies were tested for their ability to cross-react with other pl antigens or dna and for the presence of idiotypic markers known to be associated with anti-dna antibodies or antibodies to klebsiella k30 polysaccharide (k30p). affinity-purified antibodies to k30pl, phosphatidylserine ... | 1988 | 3261736 |
| comparable evaluation of orally active beta-lactam compounds in ampicillin-resistant gram-positive and gram-negative rods: role of beta-lactamases on resistance. | the antibacterial activity of the recently developed cephems cefixime and cefetamet-pivoxyl was evaluated in 408 gram-positive and gram-negative rods, all isolated recently from clinical specimens, and compared to that of other orally active agents such as ampicillin, amoxycillin + clavulanic acid, cefaclor, cefuroxime-axetil and to ceftriaxone. with regard to ampicillin-resistant enterobacteriaceae ceftriaxone proved to be the most active agent, followed by cefixime and cefetamet, whereas cefur ... | 1988 | 3262045 |
| the in vitro influence of ril2 on the b-cell dysfunction in patients with persistent generalized lymph node enlargement (pgl) or aids. | in aids elevated serum ig levels and autoimmune phenomena indicate that b cells are also involved. the human immunodeficiency virus (hiv) can be cultivated in b cells, and hiv can stimulate b cells. in order to characterize the b-cell dysfunction and conditions for modulating it, functional studies with highly purified b cells were done in four patients with pgl and hiv-positive sera. data were compared with those from patients with aids and normal controls. the experiments consisted of an in vi ... | 1988 | 3263195 |
| augmentation of host resistance to microbial infections by recombinant human interleukin-1 alpha. | recombinant human interleukin-1 alpha augmented resistance of mice to microbial infections caused by pseudomonas aeruginosa, klebsiella pneumoniae, staphylococcus aureus, streptococcus pneumoniae, salmonella typhimurium, and candida albicans. the effective doses of interleukin-1 alpha ranged from 0.01 to 10 micrograms per mouse, depending on the infecting organism, route of administration, and challenge dose. intravenous interleukin-1 alpha was, dose for dose, more effective than intravenous mur ... | 1988 | 3263325 |
| in-vitro activity and beta-lactamase stability of ly163892. | ly163892 is a new orally absorbed carbacephem. it inhibited streptococcus pyogenes and str. pneumoniae at less than or equal to 1 mg/l, but was less active against group b streptococci and groups c, f, g and bovis streptococci with mics of 1 to 2 mg/l for most but as high as 8 mg/l for some isolates. mic90 of methicillin-susceptible staphylococcus aureus was 8 mg/l, but greater than 128 mg/l for methicillin-resistant staphylococci. ly163892 had activity similar to cefaclor and cephalexin with mi ... | 1988 | 3263352 |
| extended broad-spectrum beta-lactamases conferring transferable resistance to newer beta-lactam agents in enterobacteriaceae: hospital prevalence and susceptibility patterns. | before 1985 at the pitié-salpêtrière hospital in paris (2,400 beds), resistance to cefotaxime in clinical isolates of enterobacteriaceae involved only species producing inducible class 1 beta-lactamase. between november 1985 and april 1987, however, 62 isolates (57 of klebsiella pneumoniae and five of escherichia coli) showed decreased susceptibility to cefotaxime (mean mic, 8-16 micrograms/ml). the transferability of cefotaxime resistance in e. coli k12 was demonstrated for 15 of 16 selected is ... | 1988 | 3263690 |
| simple assay of beta-lactamase with agar medium containing a chromogenic cephalosporin, pyridinium-2-azo-p-dimethylaniline chromophore (padac). | a new beta-lactamase assay method with agar plates containing pyridinium-2-azo-p-dimethylaniline chromophore (padac) (50 microm), a beta-lactamase-labile, chromogenic cephalosporin, was examined. on the padac plates inoculated with beta-lactamase-producing gram-negative bacteria (10(4) cfu per spot) and incubated at 37 degrees c, a yellow zone showing hydrolysis of padac by beta-lactamase was formed around the colony. the zone diameter increased with incubation time. examination with enterobacte ... | 1988 | 3263833 |
| in vitro activity of the combination trimethoprim plus sulfamethoxazole compared with that of other chemotherapeutic agents. | for many years now, the combination trimethoprim plus sulfamethoxazole (active ingredients of bactrim) has proved to be an effective chemotherapeutic agent with a broad spectrum of antibacterial activity against both gram-positive and gram-negative organisms, including beta-hemolytic streptococci, staphylococci, pneumococci, haemophilus influenza, escherichia coli, proteus mirabilis, proteus vulgaris, klebsiella, enterobacter and citrobacter. in this comparative study, the antibacterial activity ... | 1988 | 3264166 |
| in vitro antibacterial activity of fk482, a new orally active cephalosporin. | fk482 is a new orally active cephem antibiotic which offers some advantages over the commercially available oral beta-lactam antibiotics. it displayed a broad spectrum of activity in vitro against stock strains of gram-positive and gram-negative aerobes and anaerobes. fk482 was more active in vitro than cefixime (cfix), cefaclor (ccl) or cephalexin (cex) against clinical isolates of gram-positive organisms such as methicillin-sensitive staphylococcus aureus, coagulase-negative staphylococci incl ... | 1988 | 3264828 |
| induction of murine b cell proliferation and immunoglobulin synthesis by some bacterial ribosomes. | ribosomal preparations from klebsiella pneumoniae, haemophilus influenzae, streptococcus pyogenes, and streptococcus pneumoniae were investigated with respect to their activating capacity towards murine lymphoid cells. the proliferation of balb/c spleen cells was induced in a dose-dependent fashion (from 1 to 100 micrograms/ml) by ribosomes of k. pneumoniae, h. influenzae, and s. pyogenes with a peak activity at 48 or 72 hr of culture. the majority of the blast cells induced by these ribosomal p ... | 1988 | 3265981 |
| the effect of ru 41740 on the in vitro maturation of human b-cells. | we have tested the effect of a klebsiella pneumoniae extract, ru 41740, and its lipopolysaccharidic fraction (lps-lap) on the in vitro activation of human b-cells. two models have been used: the polyclonal activation induced by pokeweed mitogen and the specific antibody production to mannan, a polysaccharide extracted from the cell wall of candida albicans. we have shown that ru 41740, and especially its lipopolysaccharidic fraction, significantly increases the production of immunoglobulins and ... | 1988 | 3266199 |
| immunopotentiating activities of a low molecular weight lipopeptide, rp 56 142--studies in infectious models. | rp 56 142, n2-[n-(n-lauroyl-l-alanyl)-gamma-d glutamyl] l,l-2,6-diaminopimelamic acid belongs to a family of immunomodulating lipopeptides. its structure is directly derived from that of lauroyltetrapeptide rp 40 639 which is a mixture of two stereoisomers, one of which (with d,d-2,6 diaminopimelamic acid) is totally devoid of in vivo activity. rp 56 142 displayed potent protective activities against bacterial infections such as k. pneumoniae, l. monocytogenes or s. typhimurium (at doses ranging ... | 1988 | 3266200 |
| [antimicrobial activities of sultamicillin against clinical isolates from upper respiratory tract infections]. | sultamicillin (sbtpc) is a mutual prodrug in which ampicillin (abpc) and a potent beta-lactamase inhibitor sulbactam (sbt) are ester-bound in an equimolar ratio. sbtpc is hydrolyzed during absorption after oral administration to provide abpc and sbt for systemic circulation. in the present study, the antimicrobial activities of sbtpc against 50 isolates each of 6 species (staphylococcus aureus, klebsiella pneumoniae subsp. pneumoniae, branhamella catarrhalis, haemophilus influenzae, streptococcu ... | 1988 | 3266508 |
| [antimicrobial activity of sultamicillin against clinical isolates from upper respiratory tract infections ii]. | in an attempt to examine the effect of sulbactam (sbt) on beta-lactamase activity, three hundred clinical isolates from the infected upper respiratory tract were tested for mics and disk sensitivities of ampicillin (abpc) and sultamicillin (sbtpc). beta-lactamase production was tested using the acidometry disk method (beta-check, taito pfizer co.). for strains such as klebsiella spp. which form mucoid type colonies, we used the ss culture medium which, by reducing the influence of huge amounts o ... | 1988 | 3266883 |
| [urine bacterial flora and chemoantibiotic resistance: observations on ambulatory patients and hospitalized patients at the local health district no. 11 of fabriano (ancona)]. | this paper reports the results of a study carried out on 4614 samples of urine from inpatients and outpatients according to the sex. the positive monomicrobic urine specimens were examined and isolated strains were tested against various antimicrobial drugs. our findings showed that 43.1% of urine specimens examined from inpatients and 38.4% from outpatients proved to be positive. among the bacterial species more frequently isolated, significant differences among enterobacter spp. in males and c ... | 1988 | 3268917 |
| community-acquired bacteraemia; a prospective survey of 239 cases. | over a one-year period 239 patients with community-acquired bacteraemia were studied prospectively to evaluate their clinical profile, course and outcome. gram-negative organisms accounted for 108 (45 per cent) episodes of bacteraemia, gram-positive 121 (51 per cent) and polymicrobial 10 (4 per cent). the organisms isolated most commonly were e. coli (28.9 per cent), klebsiella spp. (7.5 per cent), s. pneumoniae (21.3 per cent), s. aureus (12.1 per cent) and haemolytic streptococci (4.6 per cent ... | 1988 | 3271335 |
| emphysematous septic arthritis due to klebsiella pneumoniae. | a 60-year-old woman with rheumatoid arthritis developed acute emphysematous septic arthritis of the knee due to klebsiella pneumoniae. she was brought to the hospital in septic shock with disseminated intravascular coagulation and had striking physical signs and roentgenograms showing distention of the knee with gas. she also had an infection of the hand with subcutaneous gas. after surgical drainage and institution of antibiotic therapy, she remained critically ill for several days but graduall ... | 1988 | 3275511 |
| effect of recombinant human interleukin-2 on the course of experimental chronic respiratory tract infection caused by klebsiella pneumoniae in mice. | the effect of recombinant human interleukin-2 (ril-2) on the course of experimental chronic respiratory tract infection caused by klebsiella pneumoniae in mice was examined. ril-2 was administered subcutaneously once a day for 7 or 14 days, starting 2 weeks after the mice were infected. administration of 2 or 20 micrograms of ril-2 per mouse daily for 7 days reduced bacterial counts in the lungs dose dependently. at a dose of 0.2 microgram per day, proliferation of bacteria in the lungs was supp ... | 1988 | 3275585 |
| regulation of nitrogenase synthesis in histidine auxotrophs of klebsiella pneumoniae with altered levels of adenylate nucleotides. | a histidine auxotrophic (hisa) mutant of klebsiella pneumoniae is phenotypically nif- when grown with 20 micrograms of histidine ml-1 but nif+ when supplied with histidine at 100 micrograms ml-1. reversion to nif+ at 20 micrograms of histidine ml-1 occurs phenotypically by the addition of 2-thiazolyl-dl-alanine or genetically by mutation in hisg; 2-thiazolyl-dl-alanine inhibits and hisg encodes phosphoribosyl phosphotransferase, the first enzyme of the histidine biosynthetic pathway which consum ... | 1988 | 3275613 |
| relapsing, bacteremic klebsiella pneumoniae meningitis in an aids patient. | the acquired immunodeficiency syndrome (aids) is manifested by severe immunologic (predominantly t-lymphocyte) abnormalities and opportunistic infections. central nervous system (cns) infections are frequent. pathogens causing cns infections in aids patients include parasites, fungi, and viruses and are similar to those reported in other states of impaired cell mediated immunity (cmi). a case of relapsing, bacteremic klebsiella pneumoniae meningitis in an aids patient is presented. | 1988 | 3276191 |
| rapid antibiotic susceptibility tests on enterobacteriaceae by atp bioluminescence. | the susceptibility of 76 clinical isolates of enterobacteriaceae to ampicillin, piperacillin and gentamicin was assessed by atp bioluminescence in a 4-h test. for most organisms tested (escherichia, klebsiella, enterobacter and serratia), there was good correlation with traditional mic values estimated on 18-h cultures. however strains of proteus mirabilis showed false resistance to the beta-lactam agents with the atp method; and concordance was achieved only after manipulation of the growth con ... | 1988 | 3276899 |
| comparative evaluation of the diffusion of tobramycin and cefotaxime out of antibiotic-impregnated polymethylmethacrylate beads. | both tobramycin and cefotaxime diffuse from antibiotic-impregnated polymethylmethacrylate (pmma) beads in quantities sufficient to inhibit the growth of bacteria on agar lawns or in broth cultures over a 28-day period. extraction of antibiotic from tobramycin or cefotaxime-impregnated pmma beads revealed that substantial amounts of both antibiotics remained within the beads despite 28 days of diffusion. diffusion of antibiotic from the pmma beads during the initial 3-5 days is much greater than ... | 1988 | 3278081 |
| management of catheter-related infections in pediatric patients. | broviac catheters are commonly used to provide parenteral nutrition and access for infusion of blood products and drugs to pediatric patients. sepsis is the most common serious complication of continued catheter use. although removal of the catheter is generally recommended when it becomes contaminated, it may not be feasible to do so without compromising patient care. we evaluated the management of catheter-related infections in pediatric patients with and without removal of catheter. seventy-s ... | 1988 | 3278159 |
| new quinolones in the treatment of joint and bone infections. | new quinolones are promising agents for use in the treatment of bone and joint infections because of their broad spectrum of activity against staphylococcal strains as well as gram-negative bacteria. their pharmacologic properties and their availability for oral administration make them the drugs of choice in the treatment of such chronic infections. pefloxacin and ciprofloxacin are the principal quinolones that have been evaluated with respect to the treatment of bone and joint infections. in t ... | 1988 | 3279491 |
| tigemonam, an oral monobactam. | tigemonam is an orally administered monobactam. at less than or equal to 1 microgram/ml it inhibited the majority of strains of escherichia coli, klebsiella spp., enterobacter aerogenes, citrobacter diversus, proteus spp., providencia spp., aeromonas hydrophila, salmonella spp., shigella spp., serratia marcescens, and yersinia enterocolitica. at less than or equal to 0.25 microgram/ml it inhibited haemophilus spp., neisseria spp., and branhamella catarrhalis. it did not inhibit pseudomonas spp. ... | 1988 | 3279906 |
| unusual behaviour of klebsiella rhinoscleromatis strains on api 20e strips. | seven klebsiella rhinoscleromatis standard cultures and two wild isolates were examined for their responses to api 20e (api system, s.a.) strips. several strains yield incostant results for arabinose fermentation test in api strips and, when positive, they were not identified. the arabinose positive test indeed, led to the numerical profiles 0004773 (not mentioned in the analytical catalogue), or 0004553 (two strains) corresponding to a klebsiella ozaenae identification. the mathematical analysi ... | 1988 | 3280950 |
| chronic extensive necrotizing abscess of the scalp. | chronic subgaleal abscesses have been extremely rare since the advent of antimicrobial therapy. the majority of reported cases have occurred as acute infections following traumatic scalp lacerations or needle electrode insertion for fetal monitoring. the rich blood supply of the head makes widespread infection from a scalp surgical wound a very unlikely occurrence. most acute infections of the scalp result in complete resolution with adequate early treatment. however, extensive purulent fibrosis ... | 1988 | 3281545 |
| bacteriocin (klebocin) typing of clinical isolates of klebsiella pneumoniae. | three-hundred-forty-two clinical isolates of klebsiella pneumoniae were subjected to bacteriocin (klebocin) typing using six standard klebocin-producer strains (153-158). the overall typability was 72.8 per cent. the predominant klebocin types found were 244 (14.3 per cent), 313 (13.7 per cent) and 113 (7.6 per cent). klebocin types 314 and 111 each contributed 5.2 per cent to the total number of isolates. no significant correlation was observed between the source of isolation and the klebocin t ... | 1988 | 3281855 |
| comparative efficacy of ciprofloxacin, ceftazidime and gentamicin, given alone or in combination, in a model of experimental septicemia due to klebsiella pneumoniae in neutropenic mice. | the therapeutic efficacy of ciprofloxacin, used alone and in combination with either ceftazidime or gentamicin, was evaluated in a model of experimental klebsiella pneumoniae septicemia in neutropenic mice. therapeutic results were compared to those achieved by treatment with ceftazidime or gentamicin alone, as well as their combination. infections were induced by i.v. injection of two strains of k. pneumoniae. therapy with i.m. antibiotics was performed in 8 h intervals for a total of 13 doses, ... | 1988 | 3283038 |
| kinetic properties of two plasmid-mediated beta-lactamases from klebsiella pneumoniae with strong activity against third-generation cephalosporins. | we determined the kinetic constants for two plasmid-mediated beta-lactamases with strong activity against third-generation cephalosporins: ctx-1 and shv-2. the enzymes had many similar properties: their synthesis was constitutive and they were significantly active against penicillins as well as cephalosporins. the two enzymes thus differed considerably from the chromosomal cephalosporinases, but bore some resemblance to the commonly-encountered plasmid-coded penicillinases, such as tem beta-lact ... | 1988 | 3283096 |
| anaerobic metabolism of the l-rhamnose fermentation product 1,2-propanediol in salmonella typhimurium. | when grown anaerobically on l-rhamnose, salmonella typhimurium excreted 1,2-propanediol as a fermentation product. upon exhaustion of the methyl pentose, 1,2-propanediol was recaptured and further metabolized, provided the culture was kept under anaerobic conditions. n-propanol and propionate were found in the medium as end products of this process at concentrations one-half that of 1,2-propanediol. as in klebsiella pneumoniae (t. toraya, s. honda, and s. fukui, j. bacteriol. 139:39-47, 1979), a ... | 1988 | 3283105 |
| comparison of ciprofloxacin assays. | two high pressure liquid chromatography methods developed independently and two different microbiological methods assayed samples containing ciprofloxacin derived from four volunteers: 46 sera, 19 saliva and 27 urine specimens. each subject had received 500 mg of ciprofloxacin by mouth, with the samples collected in the ensuing six hours. fifteen mock unknowns, prepared by adding known amounts of ciprofloxacin to normal human serum, were also assayed by the four procedures. the limits of sensiti ... | 1988 | 3283479 |
| influence of cephalosporins and iron on surface protein antigens of klebsiella pneumoniae in vivo. | the outer membrane protein (omp) profiles of klebsiella pneumoniae grown in a rabbit peritonitis model in the presence or absence of cephalosporins were investigated. six high-molecular-weight omps (mr 69,000 to 83,000) were induced under iron-depleted conditions in vitro. three of these proteins (the 69,000-mr protein [69k protein] and the 70k and 78k proteins) and trace amounts of the 73k and 75k proteins were induced in the om of bacteria infecting the peritoneal cavity of rabbits. addition o ... | 1988 | 3284461 |
| quality of powdered substitutes for breast milk with regard to members of the family enterobacteriaceae. | members of the family enterobacteriaceae were cultured from 52.5% of 141 milk substitute infant formulas which were obtained in 35 countries. the concentration did not exceed a level of 1 cfu/g in any product. the species which were isolated most frequently were enterobacter agglomerans, cloacae, enterobacter sakazakii, and klebsiella pneumoniae. if infections due to these organisms occur, it can be useful to include a check of the hygienic precautions which are taken during the preparation and ... | 1988 | 3284901 |
| radiological case of the month. klebsiella multifocal osteomyelitis. | | 1988 | 3285664 |
| effects of some metallic compounds on klebsiella. | | 1988 | 3285918 |
| bactericidal activity of ciprofloxacin, norfloxacin and ofloxacin in serum and urine after oral administration to healthy volunteers. | a 200 mg oral dose of ciprofloxacin, norfloxacin or ofloxacin was administered to six healthy male volunteers in a three way cross-over study in order to examine the kinetics in humans in relation to the bactericidal activity in serum and urine. serum concentrations for ciprofloxacin were similar to norfloxacin and lower than ofloxacin. despite this fact, ciprofloxacin showed the highest serum bactericidal titers compared to norfloxacin and ofloxacin when serum-resistant escherichia coli c14 was ... | 1988 | 3286510 |
| growth responses of environmental mastitis pathogens to long-chain fatty acids. | streptococcus uberis, streptococcus faecalis, escherichia coli, and klebsiella pneumoniae were tested for susceptibility to long-chain fatty acids predominant in teat canal keratin. antibacterial activity of free fatty acids on each bacterial species was measured after 12 h in synthetic media. growth responses of all three strains of streptococcus uberis were completely inhibited by c18:3 and those of two of three strains by c18:2 at 1 micrograms/ml. none of the fatty acids tested were bacterici ... | 1988 | 3286694 |