| clinical and microbiological profile of infectious keratitis in an area of madrid, spain. | to study antibiotic susceptibility in bacterial keratitis (bk), its profile over 10 years and its influence on ophthalmological practice. | 2017 | 28993066 |
| long-term effects of cataract surgery with topical levofloxacin on ocular bacterial flora. | to clarify the long-term effect of topical antibiotics on the ocular bacterial flora after cataract surgery. | 2017 | 28991607 |
| contamination occurs during acl graft harvesting and manipulation, but it can be easily eradicated. | why anterior cruciate ligament (acl) autograft soaking in a 5 mg/ml vancomycin solution decreases the rate of infection has not been well-explained. one hypothesis is that grafts can be contaminated during harvesting and vancomycin eradicates the bacteria. the purpose of the present study is to assess how the vancomycin solution acts against acl graft contamination during graft harvesting and preparation. | 2018 | 28988312 |
| cationic peptides from peptic hydrolysates of rice endosperm protein exhibit antimicrobial, lps-neutralizing, and angiogenic activities. | in this study, we hydrolyzed rice endosperm protein (rep) with pepsin and generated 20 fractions containing multifunctional cationic peptides with varying isoelectric point (pi) values using ampholyte-free isoelectric focusing (autofocusing). subsequently, we determined antimicrobial activities of each fraction against the pathogens prophyromonas gingivalis, propionibacterium acnes, streptocossus mutans, and candida albicans. fractions 18, 19, and 20 had pi values greater than 12 and exhibited a ... | 2017 | 28987278 |
| what is the role of the bacterium propionibacterium acnes in type 1 modic changes? a review of the literature. | this review presents a summary of the pathology and epidemiology of modic changes and the possible role of propionibacterium acnes. this information is followed by a synthesis of the most recent clinical research involved in culturing the discs of patients with degenerative disc disease for the presence of bacteria. we also discuss a randomized controlled trial that investigates the effects of antibiotics on patients with chronic low back pain and type 1 modic changes. we conclude with a brief d ... | 2017 | 28985974 |
| comparative effects of schisandrin a, b, and c on propionibacterium acnes-induced, nlrp3 inflammasome activation-mediated il-1β secretion and pyroptosis. | propionibacterium acnes, a common pathogen associated with acne, is also responsible for various surgical infections. schisandrin a, schisandrin b and schisandrin c, the representative lignans of schisandra chinensis (turcz.) baill. extract, inhibit p. acnes-induced inflammation. however, their effects on p. acnes-induced il-1β secretion and pyroptosis mediated by nlrp3 inflammasome activation remain unknown. in this study, we compared the effects of schisandrin a, b, and c (sch a, b, and c) on ... | 2017 | 28972885 |
| impact of sequential culture results on diagnosis and de-escalation of the antibiotic regimen in joint and bone infections. | according to existing guidelines, orthopedic specimens collected in joint and bone infections (jbi) in our institution are cultured on several media sets and incubated for two, seven, and 14 days. the optimal timing for de-escalation of the first-line antibiotic combination according to the culture results needs to be defined. | 2017 | 28972874 |
| glucocorticoids and toll-like receptor 2 cooperatively induce acute-phase serum amyloid a. | serum amyloid a (saa) is a highly conserved acute-phase protein and extrahepatic produced saa1/2 contributes to cutaneous inflammation. prolonged systemic or topical treatment with glucocorticoids can provoke skin diseases such as steroid-induced acne. glucocorticoids increase toll-like receptor 2 (tlr2) expression, however, an inflammatory mediator linked to this side effect remains elusive. we report that tlr2 agonists in combination with dexamethasone substantially increase saa expression and ... | 2018 | 28941781 |
| an anti-propionibacterium acnes antibody shows heterologous resistance to an actinobacillus pleuropneumoniae infection independent of neutrophils in mice. | porcine contagious pleuropneumonia is a highly fatal respiratory disease that is caused by actinobacillus pleuropneumoniae (app) and results in tremendous economic losses for the pig breeding industry worldwide. previous studies have demonstrated that propionibacterium acnes (pa) could effectively prevent app infection in mice and pigs. the humoral immune response played a primary role during this process and anti-pa antibody could mediate macrophages to kill the bacteria. however, the role of n ... | 2017 | 28929313 |
| propionibacterium acnes. | infection after implantation of ventriculo-peritoneal (vp) shunts is associated with significant morbidity and mortality. we describe a 9-year-old girl with propionibacterium acnes shunt infection with negative cerebrospinal fluid cultures, diagnosed by broad-range 16s-rrna gene pcr. this case supports the use of this molecular diagnostic technique in shunt infections, where the offending pathogens are difficult to culture using traditional methods. | 2017 | 28902005 |
| the skin bacterium propionibacterium acnes employs two variants of hyaluronate lyase with distinct properties. | hyaluronic acid (ha) and other glycosaminoglycans are extracellular matrix components in the human epidermis and dermis. one of the most prevalent skin microorganisms,propionibacterium acnes, possesses ha-degrading activity, possibly conferred by the enzyme hyaluronate lyase (hyl). in this study, we identified the hyl ofp. acnesand investigated the genotypic and phenotypic characteristics. investigations include the generation of ap. acneshylknockout mutant and hyl activity assays to determine t ... | 2017 | 28895889 |
| effectiveness of meibomian gland massage combined with topical levofloxacin against ocular surface flora in patients before penetrating ocular surgery. | to investigate the bacterial profile in the conjunctiva and meibomian glands in patients before penetrating ocular surgeries, and to compare the anti-bacterial efficacy of 0.5% levofloxacin and its combination with meibomian gland massage. | 2018 | 28890180 |
| bacterial conjugated linoleic acid production and their applications. | conjugated linoleic acid (cla) has been shown to exert various potential physiological properties including anti-carcinogenic, anti-obesity, anti-cardiovascular and anti-diabetic activities, and consequently has been considered as a promising food supplement. bacterial biosynthesis of cla is an attractive approach for commercial production due to its high isomer-selectivity and convenient purification process. many bacterial species have been reported to convert free linoleic acid (la) to cla, h ... | 2017 | 28889933 |
| forensic human identification using skin microbiomes. | the human microbiome contributes significantly to the genetic content of the human body. genetic and environmental factors help shape the microbiome, and as such, the microbiome can be unique to an individual. previous studies have demonstrated the potential to use microbiome profiling for forensic applications, however a method has yet to identify stable features of skin microbiomes that produce high classification accuracies for samples collected over reasonably long time intervals. a novel ap ... | 2017 | 28887423 |
| tanycytic ependymoma of the brain stem, presentations of rare cystic disease variants and review of literature. | the aim of this paper was to systematically review the evidence linking propionibacterium acnes (p. acnes) with the develop tanycytic ependymoma (tce) is a rare variant of ependymoma and management guidelines for patients with this disease are not established. | 2018 | 28884561 |
| inflammatory response of disc cells against propionibacterium acnes depends on the presence of lumbar modic changes. | intervertebral disc with propionibacterium acnes (p. acnes) is suggested to be an etiology of modic type i changes in the adjacent bone marrow. however it is unknown if disc cells can respond to p. acnes and if bone marrow cells respond to bacterial and disc metabolites draining from infected discs. | 2017 | 28884220 |
| acute exacerbation of organizing pneumonia leading to sudden death in a patient with sarcoidosis-lymphoma syndrome. | the subject was an 83-year-old female; she had a history of propionibacterium acnes-related sarcoidosis at the age of 79 years. at diagnosis, she was treated with clarithromycin and achieved remission. four years later, during a routine physical check-up, she presented with pulmonary opacities and swelling of multiple lymph nodes. a definitive diagnosis of lymphoma could not be made by inguinal lymph node biopsy. the patient's general condition was good, and we observed her clinical course. oh t ... | 2017 | 28883276 |
| comparative effects of schisandrin a, b, and c on acne-related inflammation. | inflammatory responses induced by propionibacterium acnes are a major etiological factor in the pathogenesis of acne vulgaris. schisandrin a, schisandrin b, and schisandrin c are the representative lignans of schisandra chinensis (turcz.) baill. extract. although anti-inflammatory effects of the lignans have been shown, their effects on acne-related inflammation caused by p. acnes have not been investigated and compared. we pretreated thp-1 human monocytic cells with 5, 10, and 20 μm schisandrin ... | 2017 | 28875271 |
| postoperative deep shoulder infections following rotator cuff repair. | rotator cuff repair (rcr) is one of the most commonly performed surgical procedures in orthopaedic surgery. the reported incidence of deep soft-tissue infections after rcr ranges between 0.3% and 1.9%. deep shoulder infection after rcr appears uncommon, but the actual incidence may be higher as many cases may go unreported. clinical presentation may include increasing shoulder pain and stiffness, high temperature, local erythema, swelling, warmth, and fibrinous exudate. generalized fatigue and s ... | 2017 | 28875126 |
| routine cultures for seemingly aseptic revision shoulder arthroplasty: are they necessary? | propionibacterium acnes has recently gained attention as the leading cause of periprosthetic joint infections (pjis) after shoulder arthroplasty. unlike pjis in the lower extremity, pjis after shoulder arthroplasty usually have an indolent course and are notoriously difficult to diagnose. most of the time, the diagnosis is made after positive intraoperative cultures are taken at the time of revision surgery. adding even more complexity to the diagnosis is the high rate of p acnes-positive cultur ... | 2017 | 28865964 |
| phenotype and antimicrobial activity of th17 cells induced by propionibacterium acnes strains associated with healthy and acne skin. | studies of the human skin microbiome suggest that propionibacterium acnes strains may contribute differently to skin health and disease. however, the immune phenotype and functions of t helper type 17 (th17) cells induced by healthy (ph) versus acne (pa) skin-associated p. acnes strains are currently unknown. we stimulated peripheral blood mononuclear cells from healthy donors and observed that pastrains induce higher il-17 levels than phstrains. we next generated phand pastrain-specific th17 cl ... | 2018 | 28864077 |
| immune discrepancies during in vitro granuloma formation in response to cutibacterium (formerly propionibacterium) acnes infection. | cutibacterium (formerly propionibacterium) acnes is involved in chronic/low-grade pathologies such as sarcoidosis or prosthetic joint infection (pji). in these diseases, granulomatous structures are frequently observed. in this study, we induced a physiological granulomatous reaction in response to different well-characterized clinical c. acnes isolates in order to investigate the cellular process during granuloma formation. three c. acnes isolates selected according to their origin (pji, sarcoi ... | 2017 | 28859990 |
| propionibacterium acnes infection in the native hip: a case report. | a sixty-five-year-old immunocompetent man with bilateral osteonecrosis of the hip and no prior surgical procedures or trauma was found to have a subacute propionibacterium acnes infection of the femoral head. to our knowledge, this is the first reported case of propionibacterium acnes infection in a native hip in the orthopaedic literature. | 2017 | 29252848 |
| effect of fk506 on the activation state of hepatic macrophages in propionibacterium acnes-treated rats. | activated hepatic macrophages can provoke massive liver necrosis following endotoxin stimulation through microcirculatory disturbances due to sinusoidal fibrin deposition in rats pretreated with heat-killed propionibacterium acnes. in these rats, fk506 (tachlorinus) administered 24 h before and at the time of endotoxin injection, significantly attenuated liver injury compared with the rats given no fk506. the effect of fk506 on hepatic macrophage activation and its action sites were studied in p ... | 1998 | 28976697 |