| nonradiological method for 3-dimensional implant position assessment using an intraoral scan: new method for postoperative implant control. | this study presents a method to verify the position of dental implants after insertion without the repeated x-ray exposure. | 2014 | 25192152 |
| creation of short microwave ablation zones: in vivo characterization of single and paired modified triaxial antennas. | to characterize modified triaxial microwave antennas configured to produce short ablation zones. | 2014 | 25156644 |
| mitochondrial dna sequence and phylogenetic evaluation of geographically disparate sus scrofa breeds. | next generation sequencing of mitochondrial dna (mtdna) facilitates studies into the metabolic characteristics of production animals and their relation to production traits. sequence analysis of mtdna from pure-bred swine with highly disparate production characteristics (mangalica blonde, mangalica swallow-bellied, meishan, turopolje, and yorkshire) was initiated to evaluate the influence of mtdna polymorphisms on mitochondrial function. herein, we report the complete mtdna sequences of five sus ... | 2015 | 25153451 |
| voluderm microneedle technology for skin treatments-in vivo histological evidence. | the growing demand for skin rejuvenation procedures with minimal down time and low risk has led to the development of fractional radiofrequency (rf) systems. the new voluderm™ rf microneedle technology creates minute columns of tissue thermal microablation. treatment triggers natural fractional healing, resulting in dermal volumizing and skin renewal. this preclinical research assessed the safety and efficacy of the voluderm through histological evaluation of morphological changes in the target ... | 2015 | 25151912 |
| histologic comparison of microscopic treatment zones induced by fractional lasers and radiofrequency. | fractional photothermolysis induces microscopic, localized thermal injury in the skin surrounded by undamaged viable tissue in order to promote wound healing. | 2014 | 25148410 |
| active dynamic infrared thermal imaging in burn depth evaluation. | the aim of this study was to find the relationship between active dynamic thermography (adt) with cold excitation and burn depth. this new modality of evaluation of burns seems to be an attractive proposal for quantitative classification, allowing proper choice of burn wound treatment: conservative or surgical, especially compared with static thermography. the work was an in vivo experiment on domestic pigs, and a small number of patients were also diagnosed as part of the study. statistical ana ... | 2015 | 25144810 |
| differentiation of meat from european wild boars and domestic pigs using polymorphisms in the mc1r and nr6a1 genes. | wild boar meat cannot be easily distinguished from domestic pig meat, especially in processed products, thus it can be fraudulently substituted with cheaper domestic pork. in this study we genotyped polymorphisms in two genes (mc1r, affecting coat color and nr6a1, associated with number of vertebrae) in 293 domestic pigs of five commercial breeds, 111 wild boars sampled in italy, and 90 in slovenia and other western balkan regions. allele and genotype frequency data were used to set up a dna-bas ... | 2014 | 25134014 |
| genome-wide analysis reveals artificial selection on coat colour and reproductive traits in chinese domestic pigs. | pigs from asia and europe were independently domesticated from c. 9000 years ago. during this period, strong artificial selection has led to dramatic phenotypic changes in domestic pigs. however, the genetic basis underlying these morphological and behavioural adaptations is relatively unknown, particularly for indigenous chinese pigs. here, we performed a genome-wide analysis to screen 196 regions with selective sweep signals in tongcheng pigs, which are a typical indigenous chinese breed. gene ... | 2015 | 25132237 |
| different distributions of prepromch and hypocretin/orexin in the forebrain of the pig (sus scrofa domesticus). | neurons producing melanin-concentrating hormone (mch) or hypocretin/orexin (hcrt) have been implicated in the sleep/wake cycle and feeding behavior. sleep and feeding habits vary greatly among mammalian species, depending in part of the prey/predatory status of animals. however, the distribution of both peptides has been described in only a limited number of species. in this work, we describe the distribution of mch neurons in the brain of the domestic pig. using in situ hybridization and immuno ... | 2014 | 25124772 |
| computed tomography for planning and postoperative imaging of transvenous mitral annuloplasty: first experience in an animal model. | to investigate the use of computed tomography (ct) to measure the mitral valve annulus size before implantation of a percutaneous mitral valve annuloplasty device in an animal trial. seven domestic pigs underwent ct before and after implantation of a cardioband™ (a percutaneously implantable mitral valve annuloplasty device) with a second-generation 128-section dual-source ct machine. implantation of the cardioband™ was performed in a standard fashion according to a protocol. animals were sacrif ... | 2015 | 25119889 |
| mixed signals from hybrid genomes. | admixture results from interbreeding between individuals from different populations or species that were previously genetically isolated from each other (fig. ). identifying admixture events in the genome is not always a straightforward task, because the genetic signature left behind fades with time as recombination events fragment the genomic segments introduced during the interbreeding event. additionally, when the genetic architecture of populations or species that admix is not very different ... | 2014 | 25088552 |
| a novel one-pot process for near-net-shape fabrication of open-porous resorbable hydroxyapatite/protein composites and in vivo assessment. | we present a mild one-pot freeze gelation process for fabricating near-net, complex-shaped hydroxyapatite scaffolds and to directly incorporate active proteins during scaffold processing. in particular, the direct protein incorporation enables a simultaneous adjustment and control of scaffold microstructure, porosity, resorbability and enhancement of initial mechanical and handling stability. two proteins, serum albumin and lysozyme, are selected and their effect on scaffold stability and micros ... | 2014 | 25063103 |
| histopathological comparative analysis of peri-implant soft tissue response after dental implant placement with flap and flapless surgical technique. experimental study in pigs. | the aim of this study was comparing the effect of flapless vs. flap technique of implant placement on inflammation degree of peri-implant soft tissue, through histopathological analysis. | 2015 | 25039366 |
| influence of the cutting edge angle of a titanium instrument on chip formation in the machining of trabecular and cortical bone. | the placement of self-tapping implants is associated with microfractures and the formation of bone chips along the cutting flutes. this study was conducted to investigate the effect of different cutting edge angles on chip formation during the machining of trabecular and cortical bone using instruments with a rough titanium surface. | 2016 | 25032776 |
| atrial natriuretic peptide and vasopressin-presence in the ciliary body of eye in the pig (sus domesticus). | the aqueous humor is produced in the ciliary body, therefore in this study we investigated the atrial natriuretic peptide (anp) and vasopressin (vp)-presence in the ciliary body of the pig eye since these peptide are involved in the homeostasis of body fluids. the results show anp-presence in the epithelial cells and in the endothelial cells of the blood vessels and vp-presence in the epithelial cells, in the endothelium of canal of schelmm and in the muscle cells of the blood vessels. these pep ... | 2014 | 25001668 |
| proteomic analysis of domestic pig pancreas during development using two-dimensional electrophoresis and matrix-assisted laser desorption/ionization-time of flight mass spectrometry. | pig pancreas may be a therapeutic resource for human diabetic patients. however, this potential is hindered by a lack of knowledge of the molecular events of pig pancreas development. in this study, the embryonic day 60, neonate and 6-month protein profiles of pig pancreas were ascertained at using two-dimensional gel electrophoresis and matrix assisted laser desorption/ionization-time of flight mass spectrometry. twenty four proteins were differentially expressed during pig pancreas development ... | 2014 | 24999358 |
| seasonal-dependent variations in metabolic status of spermatozoa and antioxidant enzyme activity in the reproductive tract fluids of wild boar/domestic pig hybrids. | this study investigated seasonal changes in the metabolic performance of spermatozoa and activity of the antioxidant enzymes in the seminal plasma of three wild boar/domestic pigs (aged 1.5 to 2.5 years) and the activity of the antioxidant enzymes in fluids of the cauda epididymidis and vesicular glands from 16 wild boar/domestic pig hybrids (aged 1 to 3 years). parameters of the sperm metabolic activity, such as total motility, mitochondrial functions, and measurements of oxygen uptake, atp con ... | 2014 | 24988857 |
| properties of novel composite meshes in chest wall reconstruction: a comparative animal study. | novel composite meshes routinely used in laparoscopic hernia repair reportedly lead to fewer and less dense visceral adhesions and may provide a viable alternative in thoracic surgery as well. | 2014 | 24987475 |
| haemodynamic differences between pancuronium and vecuronium in an experimental pig model. | to compare baseline cardiovascular function in anesthetised pigs using either pancuronium or vecuronium as a neuromuscular blocker. | 2015 | 24985148 |
| quantitative assessment of atrial regional function using motion estimation computed tomography. | we validated a novel image-based motion estimation computed tomographic (ct) technique (ime) to quantify atrial regional function in swine in vivo. | 2016 | 24983435 |
| an rna-based analysis of changes in biodiversity indices in response to sus scrofa domesticus decomposition. | despite emergent research initiatives, significant knowledge gaps remain of soil microbiology-associated cadaver decomposition. nevertheless, preliminary studies have shown that the vast diversity and complex interactions of soil microbial communities have great potential for forensic applications such as clandestine grave location and postmortem interval estimation. this study investigated changes in soil bacterial communities during pig (sus scrofa domesticus) leg decomposition. 16s rrna, inst ... | 2014 | 24967869 |
| free and sulfated steroids secretion in postpubertal boars (sus scrofa domestica). | sulfated steroids have been traditionally regarded as inactive metabolites. however, they may also serve as precursors for the production of active free steroids in target cells. in this study, we used the boar as a model to study the metabolism, transport, and function of steroid sulfates due to their high production in the porcine testicular-epididymal compartment, of which the role is unknown. to characterize the secretion of free and sulfated steroids, plasma samples were collected from six ... | 2014 | 24961601 |
| nitrogen requirements of white-lipped peccary (mammalia, tayassuidae). | a study was conducted to determine the protein requirement of the white-lipped peccary (tayassu pecari) performing a nitrogen (n) balance digestion trial. in a 4 × 4 latin square design, four adult captive male peccaries were fed four isoenergetic diets containing four different levels of n (13.3, 19.2, 28.7, and 37.1 g n/kg dry matter). after 15 days of adaptation, the total collection of feces and urine was carried out for five consecutive days. by regression analysis between n intake and n in ... | 2014 | 24958733 |
| cloning, functional characterization, and remodeling of k2p3.1 (task-1) potassium channels in a porcine model of atrial fibrillation and heart failure. | effective treatment of atrial fibrillation (af) remains an unmet need. human k2p3.1 (task-1) k(+) channels display atrial-specific expression and may serve as novel antiarrhythmic targets. in rodents, inhibition of k2p3.1 causes prolongation of action potentials and qt intervals. we used a porcine model to further elucidate the significance of k2p3.1 in large mammals. | 2014 | 24952150 |
| mitochondrial protection restores renal function in swine atherosclerotic renovascular disease. | the mechanisms responsible for renal injury in atherosclerotic renovascular disease (arvd) are incompletely understood, and few therapeutic options are available to reverse it. we hypothesized that chronic renal damage involves mitochondrial injury, and that mitochondrial protection would reduce renal fibrosis and dysfunction in arvd pigs. | 2014 | 24947415 |
| focused ultrasound to displace renal calculi: threshold for tissue injury. | the global prevalence and incidence of renal calculi is reported to be increasing. of the patients that undergo surgical intervention, nearly half experience symptomatic complications associated with stone fragments that are not passed and require follow-up surgical intervention. in a clinical simulation using a clinical prototype, ultrasonic propulsion was proven effective at repositioning kidney stones in pigs. the use of ultrasound to reposition smaller stones or stone fragments to a location ... | 2014 | 24921046 |
| population phylogenomic analysis and origin of mitochondrial dna in chinese domestic pig. | the genetic diversity of eight domestic pigs was analyzed using a hypervariable fragment in the mitochondrial (mt) dna control region; a portion of the hypervariable control region (515 bp) was sequenced from 153 samples. haplotype diversity and nucleotide diversity in yushan black pig populations were significantly higher than other populations (p < 0.01). a neighbor-joining tree was constructed from domestic pig mtdna and five wild pigs. the results indicate that there are only small differenc ... | 2016 | 24865908 |
| safety and efficacy of different paclitaxel-eluting balloons in a porcine model. | paclitaxel-eluting balloons have shown high antiproliferative efficacy in the treatment and prevention of restenosis. nevertheless, not all available devices are equally effective, which makes it interesting to compare results in a preclinical model. our objective was to assess the preclinical efficacy and safety of different devices. | 2014 | 24863594 |
| assessment of fetal cell chimerism in transgenic pig lines generated by sleeping beauty transposition. | human cells migrate between mother and fetus during pregnancy and persist in the respective host for long-term after birth. fetal microchimerism occurs also in twins sharing a common placenta or chorion. whether microchimerism occurs in multiparous mammals such as the domestic pig, where fetuses have separate placentas and chorions, is not well understood. here, we assessed cell chimerism in litters of wild-type sows inseminated with semen of transposon transgenic boars. segregation of three ind ... | 2014 | 24811124 |
| detecting mitochondrial signatures of selection in wild tibetan pigs and domesticated pigs. | selection in genomic regions is prevalent in mammals; however, the effects of selection on the mitogenome are not clearly understood. we determined the complete mitochondrial dna (mtdna) sequences from six wild tibetan pigs from the tibetan plateau and four domestic pig breeds from the lowland of neighboring southwest china. nucleotide diversity analysis using the sliding window method showed that the nucleotide diversity of wild tibetan pigs in most regions of the mitogenome was higher than tha ... | 2016 | 24810064 |
| preclinical randomised safety, efficacy and physiologic study of the silicon dioxide inert-coated axetis and bare metal stent: short-, mid- and long-term outcome. | to evaluate the short-, mid- and long-term safety, efficacy and vascular physiology of axetis silicon dioxide (sio2, abrading the micropores) inert-coated stent implantation in a randomised preclinical setting. | 2015 | 24769439 |
| the origin of bacteria responsible for bioerosion to the internal bone microstructure: results from experimentally-deposited pig carcasses. | it is unclear whether the principal forms of bioerosion that are often found within the internal microstructure of human bone are produced by intrinsic gut microbiota or exogenous bacteria from the soil. the aim of this study was to attempt to resolve this issue through the histological analysis of bone sampled from experimentally-deposited domestic pig (sus scrofa) carcasses. confirmation of either scenario will dictate how patterns of bone bioerosion can be used in reconstructions of taphonomi ... | 2014 | 24763128 |
| evaluation of genetic introgression from domesticated pigs into the ryukyu wild boar population on iriomote island in japan. | we evaluated genetic introgression from domesticated pigs into the ryukyu wild boar (rwb) population on iriomote island based on their genetic structure and diversity. we used a combination of mitochondrial dna d-loop region (596 bp) polymorphisms and 23 microsatellite markers. rwbs (n = 130) were collected from 18 locations on iriomote island and compared with 66 reference samples of european and asian domestic pigs. we identified six distinct haplotypes, involving 22 single nucleotide polymorp ... | 2014 | 24754898 |
| valsartan regulates myocardial autophagy and mitochondrial turnover in experimental hypertension. | renovascular hypertension alters cardiac structure and function. autophagy is activated during left ventricular hypertrophy and linked to adverse cardiac function. the angiotensin ii receptor blocker, valsartan, lowers blood pressure and is cardioprotective, but whether it modulates autophagy in the myocardium is unclear. we hypothesized that valsartan would alleviate autophagy and improve left ventricular myocardial mitochondrial turnover in swine renovascular hypertension. domestic pigs were r ... | 2014 | 24752430 |
| experimental ex vivo traumatic intrusion in the mandibular incisors of the farm pig, sus scrofa. | traumatic intrusion of incisor teeth occurs frequently in young children, as well as in teens and adults; however, the biological mechanisms promoting negative sequelae or recovery are not well understood (oral surg oral med oral pathol oral radiol endod 2009;107:493 and vital health stat 11 2007;248:1). modeling intrusive trauma and post-traumatic healing in an animal model offers the opportunity to define these biological mechanisms and to inform the design of treatments. the objective of this ... | 2014 | 24751110 |
| assessment of renal artery stenosis using intravoxel incoherent motion diffusion-weighted magnetic resonance imaging analysis. | diffusion-weighted magnetic resonance imaging is a powerful tool to assess renal morphology. however, its quantitative index, apparent diffusion coefficient (adc), derived from a conventional monoexponential model can vary with both functional and structural alterations as well as the choice of b values. in contrast, the intravoxel incoherent motion (ivim) biexponential model provides independent parameters that may represent broader aspects of renal pathophysiology. we hypothesized that ivim an ... | 2014 | 24743589 |
| novel rope-based sampling of classical swine fever shedding in a group of wild boar showing low contagiosity upon experimental infection with a classical swine fever field strain of genotype 2.3. | several classical swine fever (csf) epidemics in wild boar and domestic pigs in europe during the last decades have been caused by csf virus (csfv) strains of genotype 2.3. this genotype is known to be virulent leading to high morbidity and mortality. we experimentally infected two eight months old wild boar with 10(5,5) tcid50 of csfv genotype 2.3 and kept the animals together with five noninoculated wild boar of the same age. our original purpose was to evaluate a non-invasive sampling method ... | 2014 | 24698133 |
| optical nerve identification in head and neck surgery after er:yag laser ablation. | facial nerve function may be hampered by iatrogenic damage during head and neck laser surgery procedures. optical techniques can serve as a basis for feedback-controlled tissue-specific laser surgery on the jaw bone and the parotid gland. in order to preserve nerve tissue during laser surgery, the alteration of optical tissue properties through laser-tissue interactions have to be taken into account. it was the aim of this study to evaluate the viability of optical tissue differentiation through ... | 2014 | 24696381 |
| law of cooling, heat conduction and stefan-boltzmann radiation laws fitted to experimental data for bones irradiated by co2 laser. | the rate of cooling of domesticated pig bones is investigated within the temperature range of 20°c-320°c. within the afore-mentioned temperature range, it was found that different behaviors in the rate of cooling were taking place. for bones reaching a temperature within the lower temperature range of 20°c-50°c, it was found that the rate of cooling is mostly governed by the empirical newton's law of cooling. it is also shown that a transition is taking place somewhere within 50°c-100°c, where b ... | 2014 | 24688807 |
| glued versus stapled anastomosis of the colon: an experimental study to determine comparative resistance to intraluminal pressure. | this study compared the resistance of glued versus stapled anastomosis of the colon to intraluminal pressures at different times during healing. | 2014 | 24685174 |
| ophthalmic artery microcatheterization for research purposes in pigs. a technical note. | to describe a technique for micro catheterization of the external ophthalmic artery (eo) in pigs for investigational and training purposes. | 2014 | 24660750 |
| porcine skin damage thresholds for 0.6 to 9.5 cm beam diameters from 1070-nm continuous-wave infrared laser radiation. | there is an increasing use of high-power fiber lasers in manufacturing and telecommunications industries operating in the infrared spectrum between 1000 and 2000 nm, which are advertised to provide as much as 10 kw continuous output power at 1070 nm. safety standards have traditionally been based on experimental and modeling investigations with scant data available for these wavelengths. a series of studies using 1070-nm infrared lasers to determine the minimum visible lesion damage thresholds i ... | 2014 | 24658776 |
| the impact of csfv on the immune response to control infection. | the severity of the acute form of csf is responsible for the high mortality rate and has been the subject of many studies. nevertheless, some animals are likely to develop a mild, chronic, or unapparent form of the disease. paradoxically, this clinical form of the disease has not been well studied, especially regarding its pathogenesis. in this study, we investigated the infection in domestic pigs that is caused by the csfv cat01 strain, which is responsible for the 2001-2002 csfv outbreak in ca ... | 2014 | 24657786 |
| microsporidia detection and genotyping study of human pathogenic e. bieneusi in animals from spain. | microsporidia are ubiquitous parasites infecting all animal phyla and we present evidence that supports their zoonotic potential. fecal samples taken from domestic (cats and dogs), farm (pigs, rabbits and ostriches) and wild animals (foxes) from different provinces of spain were evaluated for microsporidia infection by light microscopy and pcr. after microsporidia species identification, e. bieneusi genotypes were additionally studied by sequence analysis of the its region. eighty-five samples o ... | 2014 | 24651457 |
| the influence of bicuspid aortic valves on the dynamic pressure distribution in the ascending aorta: a porcine ex vivo model. | the aim of the study was to simulate the effect of different bicuspid aortic valve configurations on the dynamic pressure distribution in the ascending aorta. | 2014 | 24644312 |
| prenatal stress produces anxiety prone female offspring and impaired maternal behaviour in the domestic pig. | numerous studies have shown that prenatal stress (pns) can have profound effects on postnatal well-being. here, the domestic pig (sus scrofa) was used to investigate pns effects owing to the direct relevance for farm animal welfare and the developing status of the pig as a large animal model in translational research. pregnant primiparous sows were exposed, in mid-gestation, to either a social stressor (mixing with unfamiliar conspecifics) or were kept in stable social groups. the ratio of level ... | 2014 | 24631303 |
| a pro23his mutation alters prenatal rod photoreceptor morphology in a transgenic swine model of retinitis pigmentosa. | functional studies have detected deficits in retinal signaling in asymptomatic children from families with inherited autosomal dominant retinitis pigmentosa (rp). whether retinal abnormalities are present earlier during gestation or shortly after birth in a subset of children with autosomal dominant rp is unknown and no appropriate animal rp model possessing visual function at birth has been available to examine this possibility. in a recently developed transgenic p23h (tgp23h) rhodopsin swine m ... | 2014 | 24618321 |
| comparison of self-efficacy and its improvement after artificial simulator or live animal model emergency procedure training. | the objective of this study is to compare post-training self-efficacy between artificial simulators and live animal training for the performance of emergency medical procedures. volunteer airmen of the 81st medical group, without prior medical procedure training, were randomly assigned to two experimental arms consisting of identical lectures and training of diagnostic peritoneal lavage, thoracostomy (chest tube), and cricothyroidotomy on either the traumaman (simulab corp., seattle, washington) ... | 2014 | 24594468 |
| effects of amlodipine and perindoprilate on the structure and function of mitochondria in ventricular cardiomyocytes during ischemia-reperfusion in the pig. | the aim of this study was to determine whether amlodipine and/or perindoprilate injected intravenously (iv) prior to ischemia exerted protective effects on mitochondria structural and functional alterations induced by ischemia and aggravated by reperfusion. heart rate, the duration of monophasic action potentials (dmap), peak of the time derivative of left ventricular pressure (lv dp/dt max), mitochondria structural and functional parameters in the left ventricle ischemic area were measured afte ... | 2015 | 24588464 |
| novel emboli protection cannula during cardiac surgery: first animal study. | stroke after open heart surgery is a major cause of morbidity and mortality. up to 60% of intraoperative cerebral events are caused by emboli generated by manipulations of the aorta during surgery. this is the first animal study evaluating the safety and efficacy of a novel aortic cannula designed to extract solid and gaseous emboli during cardiac surgery. | 2014 | 24585639 |
| abdominal hypertension and decompression: the effect on peritoneal metabolism in an experimental porcine study. | the aim of this study was to investigate the abdominal metabolic response and circulatory changes after decompression of intra-abdominal hypertension in a porcine model. | 2014 | 24530179 |
| prospects of improved classical swine fever control in backyard pigs through oral vaccination. | success in controlling classical swine fever (csf) in regions with high proportions of pigs kept in small scale and low-biosecurity production systems, often referred to as backyard production, tends to be hampered by the lack of control strategies properly addressing the peculiarities of this epidemiologically important subpopulation. under many circumstances the commonly practiced parenteral immunisation using live attenuated c-strain vaccine shows limitations concerning outreach of services a ... | 2014 | 24511822 |
| classical swine fever in europe--the current situation. | classical swine fever (csf) is considered to be one of the most important viral diseases in pigs worldwide. in many parts of the world great efforts are being undertaken to reduce economic losses caused by csf or to eradicate the disease. among the member states of the european union (eu) a harmonized strategy for diagnosis, control and eradication of csf is applied. success of the common strategy is documented by the decreasing number of outbreaks during the last decade. the present article sum ... | 2014 | 24511821 |
| genome-wide scans to detect positive selection in large white and tongcheng pigs. | due to the direction, intensity, duration and consistency of genetic selection, especially recent artificial selection, the production performance of domestic pigs has been greatly changed. therefore, we reasoned that there must be footprints or selection signatures that had been left during domestication. in this study, with porcine 60k beadchip genotyping data from both commercial large white and local chinese tongcheng pigs, we calculated the extended haplotype homozygosity values of the two ... | 2014 | 24506146 |
| import risk assessment incorporating a dose-response model: introduction of highly pathogenic porcine reproductive and respiratory syndrome into australia via illegally imported raw pork. | highly pathogenic porcine reproductive and respiratory syndrome (prrs) has spread through parts of south-east asia, posing a risk to australia. the objective of this study was to assess the probability of infection of a feral or domestic pig in australia with highly pathogenic prrs following ingestion of illegally imported raw pork. a conservative scenario was considered in which 500 g of raw pork was imported from the philippines into australia without being detected by border security, then di ... | 2014 | 24502944 |
| epicardial ablation performance of a novel radiofrequency device on the beating heart in pigs. | only bipolar clamps create reliable transmural lesions on the beating heart. this study evaluated the performance of a new radiofrequency (rf) device on the beating heart in an acute porcine model. | 2014 | 24484804 |
| differences in vessel healing following delivery of everolimus or paclitaxel: a comparative experimental study using identical stent and biodegradable polymer platforms. | we aimed to compare the vascular effects exclusive to antiproliferative agents by using identical stent and biodegradable polymeric matrices eluting everolimus (bp-ees) (carlo; balton) and paclitaxel (bp-pes) (luc-chopin2; balton) in the porcine model of coronary injury. a total of 37 stents were implanted with 110% overstretch in the coronary arteries of 14 domestic pigs: 13 bp-pes, 16 bp-ees and eight bare metal stents (bms) (chopin2; balton). coronary angiography was performed after 28 and 90 ... | 2014 | 24469344 |
| miniaturized mechanical chest compressor improves calculated cerebral perfusion pressure without compromising intracranial pressure during cardiopulmonary resuscitation in a porcine model of cardiac arrest. | one of the major goals of cardiopulmonary resuscitation (cpr) is to provide adequate oxygen delivery to the brain for minimizing cerebral injury resulted from cardiac arrest. the optimal chest compression during cpr should effectively improve brain perfusion without compromising intracranial pressure (icp). our previous study has demonstrated that the miniaturized mechanical chest compressor improved hemodynamic efficacy and the success of cpr. in the present study, we investigated the effects o ... | 2014 | 24463224 |
| immunohistochemical analysis of blood vessels in peri-implant mucosa: a comparison between mini-incision flapless and flap surgeries in domestic pigs. | the aim of this experimental study is to compare the effect of mini-incision flapless versus flap technique of implant placement on the amount of vascular structures and blood vessel elements in peri-implant soft tissue, using immunohistochemical analysis. | 2015 | 24438481 |
| cell proliferation in the seminiferous and epididymal epithelia of sus domesticus. | it is important to understand the proliferative activity of the different structures of the male reproductive apparatus in livestock species, such as sus domesticus, to ensure reproductive efficiency. the main aims of this study were (a) to evaluate the proliferative activity of the spermatogonia in the different stages of the seminiferous cycle and (b) to study the cell proliferation in the epididymal epithelium in each region, identifying the different cells involved. for this, the testes and ... | 2014 | 24418529 |
| development of an animal model of fibrous cholangitis in pigs. | the aim of this study was to develop a model of fibrous cholangitis in the offspring of gravid domestic pigs through the administration of 1,4-phenylene diisothiocyanate (ditc). | 2014 | 24410545 |
| the limit of anemia tolerance during hyperoxic ventilation with pure oxygen in anesthetized domestic pigs. | during acellular replacement of an acute blood loss, hyperoxic ventilation (hv) increases the amount of o2 physically dissolved in the plasma and thereby improves o2 supply to the tissues. while this effect could be demonstrated for hv with inspiratory o2 fraction (fio2) 0.6, it was unclear whether hv with pure oxygen (fio2 1.0) would have an additional effect on the physiological limit of acute normovolemic anemia. | 2013 | 24401552 |
| retrograde flush is more protective than heparin in the uncontrolled donation after circulatory death lung donor. | formation of microthrombi after circulatory arrest is a concern for the development of reperfusion injury in lung recipients from donation after circulatory death (dcd) donors. in this isolated lung reperfusion study, we compared the effect of postmortem heparinization with preharvest retrograde pulmonary flush or both. | 2014 | 24378013 |
| qualitative tissue differentiation by analysing the intensity ratios of atomic emission lines using laser induced breakdown spectroscopy (libs): prospects for a feedback mechanism for surgical laser systems. | the research work presented in this paper focuses on qualitative tissue differentiation by monitoring the intensity ratios of atomic emissions using 'laser induced breakdown spectroscopy' (libs) on the plasma plume created during laser tissue ablation. the background of this study is to establish a real time feedback control mechanism for clinical laser surgery systems during the laser ablation process. ex-vivo domestic pig tissue samples (muscle, fat, nerve and skin) were used in this experimen ... | 2015 | 24376030 |
| molecular detection and genetic analysis of porcine bocavirus in korean domestic swine herds. | several porcine bocaviruses have been detected worldwide, and this report is the first to describe this virus in a korean domestic swine herd. we identified porcine bocavirus in various samples, including serum, tissue, feces and saliva, which revealed that porcine bocavirus predominates in korean domestic swine populations. the results of this study also suggested that porcine bocaviruses primarily infect weaned piglets. phylogenetic analysis of the orf3 gene was performed to determine the gene ... | 2014 | 24352435 |
| [influence of the depth of retained denatured dermis on the survival rate of grafted skin in burn swine with deep partial-thickness burn]. | to explore the influence of the thickness of retained denatured dermis on the survival rate of grafted skin in swine with deep partial-thickness burn. | 2013 | 24351536 |
| cardiac expression and atrial fibrillation-associated remodeling of k₂p2.1 (trek-1) k⁺ channels in a porcine model. | effective management of atrial fibrillation (af) often remains an unmet need. cardiac two-pore-domain k(+) (k2p) channels are implicated in action potential regulation, and their inhibition has been proposed as a novel antiarrhythmic strategy. k2p2.1 (trek-1) channels are expressed in the human heart. this study was designed to identify and functionally express porcine k2p2.1 channels. in addition, we sought to analyze cardiac expression and af-associated k2p2.1 remodeling in a clinically releva ... | 2014 | 24345461 |
| infrared skin damage thresholds from 1319-nm continuous-wave laser exposures. | a series of experiments were conducted in vivo using yucatan miniature pigs (sus scrofa domestica) to determine thermal damage thresholds to the skin from 1319-nm continuous-wave nd:yag laser irradiation. experiments employed exposure durations of 0.25, 1.0, 2.5, and 10 s and beam diameters of ∼0.6 and 1 cm. thermal imagery data provided a time-dependent surface temperature response from the laser. a damage endpoint of fifty percent probability of a minimally visible effect was used to determine ... | 2013 | 24343435 |
| expression and genomic imprinting of the porcine rasgrf1 gene. | imprinted genes play important roles in mammalian growth, development and behavior. the rasgrf1 (ras protein-specific guanine nucleotide exchange factor 1) gene has been identified as an imprinted gene in mouse and rat. in the present study, we detected its sequence, imprinting status and expression pattern in the domestic pigs. a 228 bp partial sequence located in exon 14 and a 193 bp partial sequence located in exon 1 of the rasgrf1 gene in domestic pigs were obtained. a g/a transition, was id ... | 2014 | 24342659 |
| dynamic changes in nuclear import of a nuclear localisation signal-bearing substrate in 8-cell stage porcine embryos. | coordinated intracellular trafficking is critically important for proper timing of major cellular events during embryogenesis. nuclear import mediated by the karyopherin α/β (importin α/β) heterodimer is perhaps the best characterised nuclear trafficking system in eukaryotic cells. seven karyopherin α subtypes have been identified in the domestic pig, and although each karyopherin α subtype transports proteins bearing classical nuclear localisation signals (nlss), individual karyopherin α subtyp ... | 2015 | 24342392 |
| case report: pig attack with successful postexposure prophylaxis management. | the domesticated pig or boar is ubiquitous to agriculture around the world and is an important food product in most countries. the males that are able to grow tusks that can approach 5 in are the primary contributor to morbidity and mortality from boar attacks. literature surrounding domesticated boar attacks is sparse. there are no published cases of domesticated boar attacks that describe successful bacterial postexposure prophylaxis. we present a case report of an attack on an adult female by ... | 2014 | 24332899 |
| transumbilical endoscopic cholecystectomy in a porcine model. | natural orifice transluminal endoscopic surgery (notes) is a new technique. this study describes our initial experience of notes and investigates the feasibility of transumbilical endoscopic cholecystectomy (tuec). | 2013 | 24316742 |
| therapeutic safety of high myocardial expression levels of the molecular inotrope s100a1 in a preclinical heart failure model. | low levels of the molecular inotrope s100a1 are sufficient to rescue post-ischemic heart failure (hf). as a prerequisite to clinical application and to determine the safety of myocardial s100a1 dna-based therapy, we investigated the effects of high myocardial s100a1 expression levels on the cardiac contractile function and occurrence of arrhythmia in a preclinical large animal hf model. at 2 weeks after myocardial infarction domestic pigs presented significant left ventricular (lv) contractile d ... | 2014 | 24305416 |
| synthesis of α-collagen fragments and research of their influence on the degree of hydration of a model of epidermis. | in recent years the interest into areas of science, such as cosmetology, dermatology, pharmacology or aesthetic medicine has increased significantly. scientists are more frequently looking for ingredients that affect the skin's condition and slow down the aging process. practically every year, the scientists discover a number of new chemical substances (both natural and synthetic) that can be potentially used to manufacture cosmetics. | 2013 | 24278040 |
| porcine hokovirus in domestic pigs, cameroon. | | 2013 | 24274159 |
| dental implant macro-design features can impact the dynamics of osseointegration. | the purpose of this study was to compare the clinical performance of two dental implant types possessing a different macro-design in the in vivo pig model. | 2015 | 24238310 |
| post-burning fragmentation of calcined bone: implications for remains recovery from fatal fire scenes. | this research assesses how short term delays in time-until-recovery can affect the quality and quantity of burnt bone recovered from a fatal fire scene. knowledge of trends in post-burning remains fragmentation will enable investigators to prioritise remains recovery and implement recovery protocols appropriately. by comparing calcined bone fragments recovered 0, 24, 56 and 168 h (1 week) after experimental burns, this research describes remains fragmentation over time. sus scrofa (domestic pig) ... | 2013 | 24237832 |
| iridescence in meat caused by surface gratings. | the photonic structure of cut muscle tissues reveals that the well-ordered gratings diffract light, producing iridescent colours. cut fibrils protruding from the muscle surface create a two-dimensional periodic array, which diffract light at specific wavelengths upon illumination. however, this photonic effect misleads consumers in a negative way to relate the optical phenomenon with the quality of the product. here we discuss the fundamentals of this optical phenomenon and demonstrate a methodo ... | 2013 | 28239133 |
| juvenile domestic pigs (sus scrofa domestica) use human-given cues in an object choice task. | research on the comprehension of human-given cues by domesticated as well as non-domesticated species has received considerable attention over the last decade. while several species seem to be capable of utilizing these cues, former work with domestic pigs (sus scrofa domestica) has shown inconclusive results. in this study, we investigated the use of human-given cues in an object choice task by young domestic pigs (n = 17; 7 weeks of age) who had very limited human contact prior to the experime ... | 2014 | 24197275 |
| the expression of mitochondrial, cytoplasmic and extracellular superoxide dismutase in the colonic wall of pigs suffering from swine dysenteria. | the expression of 3 types of peroxide dismutase (sod1, sod2 and sod3) was studied with real-time pcr in the colonic wall of domestic pig suffering from swine dysentery. the expression of enzymes was studied separately in the mucosa and the muscular membrane. it was found that in the mucosa the expression of sod1 (cytoplasmic) did not change, while the levels of expression of mitochondrial sod2 and extracellular sod3 were raised in inflamed colon. more dramatic changes were seen in the muscular m ... | 2013 | 24195279 |
| beta radiation for renal nerve denervation: initial feasibility and safety. | in small clinical trials, sympathetic renal denervation using radiofrequency (rf) energy shows promise in treating resistant hypertension. however, the rf procedure is lengthy and is associated with pain during ablation. vascular brachytherapy, a proven treatment for in-stent restenosis, has the potential to cause nerve fibrosis. the purpose of the present study was to assess the safety and feasibility of renal artery brachytherapy for sympathetic renal denervation. | 2013 | 24169134 |
| genomic analyses identify distinct patterns of selection in domesticated pigs and tibetan wild boars. | we report the sequencing at 131× coverage, de novo assembly and analyses of the genome of a female tibetan wild boar. we also resequenced the whole genomes of 30 tibetan wild boars from six major distributed locations and 18 geographically related pigs in china. we characterized genetic diversity, population structure and patterns of evolution. we searched for genomic regions under selection, which includes genes that are involved in hypoxia, olfaction, energy metabolism and drug response. compa ... | 2013 | 24162736 |
| microvascular perfusion as a target for fluid resuscitation in experimental circulatory shock. | to study regional perfusion during experimental endotoxemic and obstructive shock and compare the effect of initial cardiac output-targeted fluid resuscitation with optimal cardiac output-targeted resuscitation on different peripheral tissues. | 2014 | 24158169 |
| mechanical ventilation during cardiopulmonary resuscitation with intermittent positive-pressure ventilation, bilevel ventilation, or chest compression synchronized ventilation in a pig model. | mechanical ventilation with an automated ventilator is recommended during cardiopulmonary resuscitation with a secured airway. we investigated the influence of intermittent positive-pressure ventilation, bilevel ventilation, and the novel ventilator mode chest compression synchronized ventilation, a pressure-controlled ventilation triggered by each chest compression, on gas exchange, hemodynamics, and return of spontaneous circulation in a pig model. | 2014 | 24158168 |
| tissue discrimination by uncorrected autofluorescence spectra: a proof-of-principle study for tissue-specific laser surgery. | laser surgery provides a number of advantages over conventional surgery. however, it implies large risks for sensitive tissue structures due to its characteristic non-tissue-specific ablation. the present study investigates the discrimination of nine different ex vivo tissue types by using uncorrected (raw) autofluorescence spectra for the development of a remote feedback control system for tissue-selective laser surgery. autofluorescence spectra (excitation wavelength 377 ± 50 nm) were measured ... | 2013 | 24152930 |
| performance of a novel bipolar/monopolar radiofrequency ablation device on the beating heart in an acute porcine model. | although the advent of ablation technology has simplified and shortened surgery for atrial fibrillation, only bipolar clamps have reliably been able to create transmural lesions on the beating heart. currently, there are no devices capable of reproducibly creating the long linear lesions in the right and left atria needed to perform a cox-maze procedure. this study evaluated the performance of a novel suction-assisted radiofrequency device that uses both bipolar and monopolar energy to create le ... | 2017 | 24145972 |
| prolonged therapeutic hypothermia is more effective in attenuating brain apoptosis in a swine cardiac arrest model. | to investigate whether 48 hours of therapeutic hypothermia is more effective to attenuate brain apoptosis than 24 hours and to determine whether the antiapoptotic effects of therapeutic hypothermia are associated with the suppressions of the cleavage of protein kinase c-δ, the cytosolic release of cytochrome c, and the cleavage of caspase 3 in a swine cardiac arrest model. | 2014 | 24145844 |
| utility of 64-msct in assessing acute non-reperfused myocardial infarct size. | to evaluate the utility of multi-slice computed tomography (msct) in assessing acute non-reperfused myocardial infarct size. | 2013 | 24133512 |
| cerebral blood flow quantification in swine using pseudo-continuous arterial spin labeling. | to develop quantitative cerebral blood flow (cbf) imaging using pseudo-continuous arterial spin labeling (pcasl) in swine, accounting for their cerebrovascular anatomy and physiology. | 2013 | 24105693 |
| modeling of the renal kinetics of the at1 receptor specific pet radioligand [11c]kr31173. | the radioligand [(11)c]kr31173 has been introduced for pet imaging of the angiotensin ii subtype 1 receptor (at1r). the purpose of the present project was to employ and validate a compartmental model for quantification of the kinetics of this radioligand in a porcine model of renal ischemia followed by reperfusion (ir). | 2013 | 24083243 |
| radiologic advantages of potential use of polymer plastic clips in neurosurgery. | plastic clips are made of diamagnetic material and may result in fewer computed tomography (ct) and magnetic resonance artifacts than titanium clips. considering that polymer plastic clips are increasingly being used in endoscopic surgery, our study examined the ct and magnetic resonance imaging (mri) characteristics of plastic clips after application in the neurocranium and compared them with titanium clips. | 2016 | 24067738 |
| extrinsic primary afferent neurons projecting to the pylorus in the domestic pig--localization and neurochemical characteristics. | the pig, as an omnivorous animal, seems to be especially valuable species in "gastrointestinal" experiments. the importance of the pylorus in the proper functioning of the digestive tract is widely accepted. although it is commonly known that sensory innervation plays an important role in the regulation of gastric activity and gastrointestinal tissue resistance, there is complete lack of data on the extrinsic afferents projecting to the swine pylorus. the present experiment has been designed to ... | 2014 | 24052481 |
| comparative histology and immunohistochemistry of porcine versus human skin. | porcine skin is increasingly being employed as a model of human skin in various research fields, including pharmacology, toxicology and immunology, with particular interest in percutaneous permeation and organ transplantation. porcine skin shows several anatomical and physiological similarities, but also some differences, with human skin, but few in depth comparative studies are so far available. | 2013 | 24047577 |
| confirmation of intraosseous cannula placement based on pressure measured at the cannula during squeezing the extremity in a piglet model. | we sought to assess the reliability of the method using the pressure measured at the intraosseous (io) cannula while squeezing the involved limb (p(squeezing)) in determining the position of the io needle and to compare its performance with that of the traditional confirmation method. | 2014 | 24036195 |
| immediate graft histological assay, post pig's liver transplantation. | to describe the vascular and tissue histopathological changes in seven sequential experimental liver transplantations in pigs. | 2013 | 24000062 |
| characterization of microthermal zones induced by fractional radiofrequency using reflectance confocal microscopy: a preliminary study. | the microthermal zone (mtz) produced by fractional device have been mostly evaluated through histopathologic analysis. study of ablative type mtz created by fractional device and skin thermal interaction using in vivo reflectance confocal microscopy (rcm) has been rarely reported. | 2013 | 23996648 |
| growing cava vein anastomosis: comparison of cross-clamping and suture times using vcs metallic clips, interrupted nonabsorbable, or continuous absorbable suturing techniques. | the latest generation in titanium clip application systems, the anastoclip vessel closure system (vcs; lemaitre vascular, burlington, ma), allows surgeons to perform vascular anastomosis more easily and faster than conventional sutures. this system may become the option of choice for vascular reconstruction in pediatric surgery where, as in the case transplant surgery, decreasing vascular occlusion times may influence outcome. the aim of this study was to determine whether vcs metallic clips wou ... | 2013 | 23993110 |
| archaeology. european hunter-gatherers dined on domestic pigs. | | 2013 | 23990538 |
| bacterial populations associated with early-stage adipocere formation in lacustrine waters. | the preservation of soft tissue is a valuable evidence for forensic investigation as it may provide information about the cause and manner of death as well as the time since death. adipocere forms from the conversion of triglycerides in the neutral fats into stable fatty acids producing a solid white product which aids tissue preservation. adipocere will typically form in water-logged grave sites and aquatic environments. documentation on the chemical and microbiological changes that cause adipo ... | 2014 | 23989223 |
| the effect of high-fat diet on the composition of the gut microbiota in cloned and non-cloned pigs of lean and obese phenotype. | the aim of this study was to investigate the effect of high-far-high-energy diet on cloned and non-cloned domestic pigs of both lean and obese phenotype and to evaluate if the lean cloned pigs had a lower inter-individual variation as compared with non-cloned pigs. the microbiota of colon and terminal ileum was investigated in cloned and non-cloned pigs that received a high-far-high-energy diet with either restricted or ad libitum access to feed, resulting in lean and obese phenotypes, respectiv ... | 2017 | 23974297 |