| dynamic mrna expression analysis of the secondary palatal morphogenesis in miniature pigs. | normal mammalian palatogenesis is a complex process that requires the occurrence of a tightly regulated series of specific and sequentially regulated cellular events. cleft lip/palate (clp), the most frequent craniofacial malformation birth defects, may occur if any of these events undergo abnormal interference. such defects not only affect the patients, but also pose a financial risk for the families. in our recent study, the miniature pig was shown to be a valuable alternative large animal mod ... | 2019 | 31480549 |
| endogenous retroviruses drive resistance and promotion of exogenous retroviral homologs. | endogenous retroviruses (ervs) serve as markers of ancient viral infections and provide invaluable insight into host and viral evolution. ervs have been exapted to assist in performing basic biological functions, including placentation, immune modulation, and oncogenesis. a subset of ervs share high nucleotide similarity to circulating horizontally transmitted exogenous retrovirus (xrv) progenitors. in these cases, erv-xrv interactions have been documented and include (a) recombination to result ... | 2020 | 33290087 |