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nonsense mutation in pmel is associated with yellowish plumage colour phenotype in japanese quail.the l strain of japanese quail exhibits a plumage phenotype that is light yellowish in colour. in this study, we identified a nonsense mutation in the premelanosome protein (pmel) gene showing complete concordance with the yellowish plumage within a pedigree as well as across strains by genetic linkage analysis of an f2 intercross population using approximately 2,000 single nucleotide polymorphisms (snps) that were detected by double digest restriction site-associated dna sequencing (ddrad-seq). ...201830425278
effect of pennyroyal, savory and thyme essential oils on japanese quail physiology.an experiment was conducted to show the effects of different levels of pennyroyal, thyme and savory essential oils dietary supplementation on performance, organs weight, intestinal morphology, and serum lipids in quails. a total of 550 day-old japanese quail chicks were allocated into 11 dietary treatments of 5 replications (10 birds in each cage) under a randomized experimental design. the treatments were a basal diet (control), or 3 levels (200, 300, and 400 ppm) of thyme essential oil (to), o ...201830417147
comparative and evolutionary aspects of gonadotropin-inhibitory hormone and fmrfamide-like peptide systems.gonadotropin-inhibitory hormone (gnih) is a hypothalamic neuropeptide that was found in the brain of japanese quail when investigating the existence of rfamide peptides in birds. gnih was named because it decreased gonadotropin release from cultured anterior pituitary, which was located in the hypothalamo-hypophysial system. gnih and gnih precursor gene related peptides have a characteristic c-terminal lpxrfamide (x = l or q) motif that is conserved in jawed vertebrates. orthologous peptides to ...201830405335
neural activation following offensive aggression in japanese quail.aggression is a fundamental part of animal social behaviour. in avian species, little is known about its neural representation. in particular, neural activity following offensive aggression has not been studied in detail. here, we investigated the patterns of brain activation using immediate-early gene (ieg) expression in male japanese quail that showed pronounced aggressive behaviours during a 30 min male-male interaction and compared them to those of males that did not interact with a conspeci ...201830404900
supplementation of l-glycine and l-glutamate to japanese quails from 01 to 36 days of age using the ideal protein concept.experiment i: t1-1 =  basal diet with 25% crude protein (cp) + limiting amino acids (la); t1-2  = 20% cp + la; t1-3  = 20% cp + la + l-glycine; t1-4  = 20% cp + la + l-glutamate; t1-5  = 20% cp + la + l-glycine + l-glutamate. experiment ii: t2-1  = basal diet with 22% cp + la; t2-2  = 20% cp + la; t2-3  = 17.6% cp + la + l-glycine; t2-4  = 17.6% cp + la + l-glutamate; t2-5  = 17.6% cp + la + l-glycine + l-glutamate. the reduction of dietary protein based on the concept of ideal protein decreases ...201930402888
comparative effect of the inclusion of zootechnical additives in the feed of japanese quails in two productive phases.this study aimed to evaluate the intestinal morphology, performance and financial analysis of the inclusion of additives in the feed during the productive period of 360 japanese quails distributed in a completely randomized design in a split plot scheme in time with five treatments and eight repetitions of nine birds each. the treatments were: control, antibiotic, prebiotic, probiotic and synbiotic. the variables were: height, width and width/height ratio of the villi, crypt depth and villus/cry ...201930365709
a trait for a high emotionality favors spatial memory to the detriment of cue-based memory in japanese quail.recent studies provided evidence that a personality trait such as a trait for a high or a low emotionality can either promotes or impairs learning and memory performances. this variability can be partly explained because this trait may have opposite effect on memory performances depending on the memory system involved. the present study investigated in japanese quail the relationships between emotionality and two forms of memory, spatial- memory and cue-based memory. we showed that birds with a ...201830359691
effect of dietary sodium butyrate supplementation on growth, blood biochemistry, haematology and histomorphometry of intestine and immune organs of japanese quail.new strategies must be developed to improve poultry performance and health. one of these strategies is the use of supplementations as sodium butyrate (sb) to improve the physiological status and then increasing the growth performance, but the best period of age in which the addition of sb is more effective on birds is not well understood. therefore, the aim of this study was to investigate the effect of dietary inclusion of sb supplementation through the first, second or whole growth period on s ...201930333074
modulation of heat-shock response is associated with di (2-ethylhexyl) phthalate (dehp)-induced cardiotoxicity in quail (coturnix japonica).di(2-ethylhexyl) phthalate (dehp) is an omnipresent environmental pollutant with endocrine disrupting properties. as a plasticizer, dehp can be leach from the plastic to transfer the external environment and thus enters the animal food chain, causing serious damage to the animal organs. the heat-shock response (hsr) comprising heat-shock protein (hsps) and heat-shock transcription factor (hsfs) plays a pivotal role in various toxic stress conditions. for the sake of investigating the effects of ...201930300839
impacts of various storage periods on egg quality, hatchability, post-hatching performance, and economic benefit analysis of two breeds of quail.the effect of storage period on hatching and post-hatching performance of two quail breeds (brown japanese quail (bjq) and french white quail (fwq)) was investigated using 940 eggs from each breed. eggs were divided into four equal groups (235 eggs each), in each group. a total number of 210 eggs were used for incubation (with three replicates, 70 eggs each) and additional 25 eggs served as samples for egg quality parameters, each group was kept for special storage period. the first group was in ...201930299459
synergistic effect of phage therapy using a cocktail rather than a single phage in the control of severe colibacillosis in quails.infections associated with avian pathogenic escherichia coli (apec) cause severe economic losses to the poultry industry. the study presented herein investigated the in vivo performance of a single phage with prolonged in vivo and in vitro survivability alone or in combination with 3 other selected phages in treating colibacillosis in quails. japanese quails (n = 360) were randomly assigned to 6 treatment groups with 4 replicate pens. birds from the control groups (groups i, ii, and iii) were tr ...201930289491
di(2-ethylhexyl) phthalate induced hepatotoxicity in quail (coturnix japonica) via modulating the mitochondrial unfolded protein response and nrf2 mediated antioxidant defense.among ubiquitously found environmental contaminants in the ecosystem, di(2-ethylhexyl) phthalate (dehp) is an important environmental contaminant used as plasticizer in medical and consumer goods. the bioaccumulation and environmental persistence of dehp cause serious global health effects in wildlife animals and human, especially hepatotoxicity. herein, to explore the mechanisms of dehp induced hepatotoxicity, quail were exposed with 0, 250, 500 and 1000 mg/kg bw/day dehp by gavage administrati ...201930257229
fasting and refeeding induce differential changes in hypothalamic mrna abundance of appetite-associated factors in 7 day-old japanese quail, coturnix japonica.there is little information regarding effects of fasting on feeding behavior and hypothalamic physiology in young japanese quail. the aim was thus to measure food intake and hypothalamic mrna in response to fasting and refeeding. five d-old quail ate little during the dark cycle. food intake was greatest during the first 2 h of the light cycle. six day-old quail fasted for 6 h ate the most during the first 15 min of refeeding. in 7 d-old quail, 3 h of fasting up-regulated hypothalamic neuropepti ...201930236911
intestinal mucosa develops in a sex-dependent manner in japanese quail (coturnix japonica) fed saccharomyces cerevisiae.1. the aim of study was to investigate whether the impact of the yeast saccharomyces cerevisiae on the histological structure of the intestine, innervation of the small intestine wall, and basal biochemical serum parameters in japanese quail was sex dependent. 2. one-day-old healthy male and female japanese quail were fed either a basal diet containing no yeast (control group) or the basal diet plus 1.5% (15 g/kg of diet) of yeast (s. cerevisiae inactivated by drying). samples from the duodenum ...201830229673
predicting chemical, enzymatic and nutritional properties of fermented barley (hordeum vulgare l.) by second derivate spectra analysis from attenuated total reflectance-fourier transform infrared data and its nutritional value in japanese quails.nutrient concentrations, enzyme activities, viable probiotic counts and organic acid levels of fermented barley (fb) produced by solid state fermentation (ssf) and of its unfermented counterpart (unfermented barley (ufb)) were determined by quantitative methods, and compared with the second derivate spectra analysis (sdsa) of their attenuated total reflectance-fourier transform infrared measurements. moreover, in order to test the nutritional value of fb and ufb feeds, 3-d old japanese quails we ...201830183393
estimation of additive and non-additive genetic variances of body weight in crossbreed populations of the japanese quail.a major part of the growth performance in birds is the result of the combined effects of genes, including the general and specific combining ability that requires the design of an optimal mating system. the aim of this study was to fit the best model for each body weight trait from hatch to 45 days and the estimation of the variance components and the genetic parameters for the body weight traits of a crossbred population. this crossbred population was created by 4 strains of japanese quail, inc ...201930169748
evaluation of thyme and ajwain as antibiotic growth promoter substitutions on growth performance, carcass characteristics and serum biochemistry in japanese quails (coturnix japonica).the present study was to evaluate thyme and ajwain as antibiotic growth promoter substitutions on growth performance, carcass characteristics and serum biochemistry in japanese quails (coturnix japonica). a feeding trial was conducted over 28 d with 4 groups of japanese quails fed experimental diets formulated to provide no supplementation (control), or control + 55 mg zinc bacitracin/kg, 2 g thyme/kg, and 2 g ajwain/kg. at 35 d of age, 2 quails from each replicate were sacrificed and eviscerate ...201830167488
effects of clove (syzygium aromaticum) oil on quail growth, carcass traits, blood components, meat quality, and intestinal microbiota.to provide a safe growth promoter, the present study has investigated the effects of different levels of cold-pressed clove oil (ccpo) on growth performance, carcass traits, blood biochemistry, and intestinal microbial population of growing japanese quails. a total of 300 quails (1-wk old) were randomly divided into 3 treatment groups: control basal diet, basal diet +0.75 ml oil/kg diet, and basal diet +1.5 ml oil/kg diet. quails fed with 1.5 ml clove oil/kg diet showed a 3.43% improvement in li ...201930165540
di (2-ethyl hexyl) phthalate (dehp)-induced kidney injury in quail (coturnix japonica) via inhibiting hsf1/hsf3-dependent heat shock response.di (2-ethyl hexyl) phthalate (dehp) as a plasticizer can leach away from the plastic and hence entrances into the animal food chain which caused serious hazard in organs of animals, but there are few studies on dehp kidney toxicity. the heat-shock response (hsr) consisting of the hsps and hsfs plays an important role in various toxicity stress conditions. to investigate the influence on kidney toxicity and the modulation of hsr during dehp exposure, female quail were fed the diet with 0, 250, 50 ...201830114749
crosstalk between unfolded protein response and nrf2-mediated antioxidant defense in di-(2-ethylhexyl) phthalate-induced renal injury in quail (coturnix japonica).the widely used di-(2-ethylhexyl) phthalate (dehp) has been reported to exhibit ubiquitous environmental and global health hazards. the bioaccumulation and environmental persistence of dehp can cause serious health hazards in wildlife animals and human. however, dehp-induced nephrotoxicity in bird is remained unknown. thus, this study explored the related mechanism of dehp nephrotoxicity in quail. for this purpose, quail were exposed with dehp at doses of 0, 250, 500, and 1000 mg/kg body weight ...201830077409
specific neural phase relation of serotonin and dopamine modulate the testicular activity in japanese quail.specific phase relation of serotonin and dopamine modulate the hypothalamo-hypophyseal-gonadal axis as well as photosexual responses in japanese quail, but the effect of these specific phase relations on testicular activity and steroidogenesis is not yet been investigated. we hypothesized that temporal phase relation induced alteration in local testicular gonadotropin-releasing hormone (gnrh)-gonadotropin-inhibitory hormone (gnih) and their receptor system may modulate the testicular activity an ...201930073648
changes in neurogenesis with post‑hatching age in the male japanese quail (cortunix japonica) brain.most avian neurogenesis studies have previously focused on the song control system and little attention has been given to non‑song birds. the objective of this study was to assess changes in neurogenesis associated with post‑hatching age (3‑12 weeks) in the japanese quail brain using proliferating cell nuclear antigen (pcna) and doublecortin (dcx) immunohistochemistry. pcna‑immunoreactive (ir) cells were observed mainly in the olfactory bulb ventricular zone, telencephalic ventricular zones and ...201830019708
di (2-ethylhexyl) phthalate (dehp)-induced hepatotoxicity in quails (coturnix japonica) via triggering nuclear xenobiotic receptors and modulating cytochrome p450 systems.di (2-ethylhexyl) phthalate (dehp) is a widely distributed pollutant that is of great concern due to its negative health effects. however, whether dehp exposure causes liver toxicity in birds remains unclear. to clarify the potential hepatotoxicity of dehp, quails were exposed to 0, 250, 500 and 1000 mg/kg bw/day dehp by gavage treatment for 45 days. the livers of dehp-exposed quails showed histomorphological changes. dehp exposure induced a significant increase in cytochrome p450 enzyme system ...201830017959
thymol supplementation effects on adrenocortical, immune and biochemical variables recovery in japanese quail after exposure to chronic heat stress.chronic heat stress (chs) exposure negatively impairs avian' immunoneuroendocrine interplay. thymol has shown several bioactive properties including antioxidant, bactericidal, antifungal and gamma-aminobutyric acid modulator activities. indeed, supplementation with thymol has been used with positive effects on poultry production and immune-related variables. this study evaluates whether a thymol dietary supplementation can be used as a new functional feed strategy to mitigate chs deleterious eff ...201929983133
female japanese quail visually differentiate testosterone-dependent male attractiveness for mating preferences.biased mating due to female preferences towards certain traits in males is a major mechanism driving sexual selection, and may constitute an important evolutionary force in organisms with sexual reproduction. in birds, although the role of male ornamentation, plumage coloration, genetic dissimilarity, and body size have on mate selection by females have been examined extensively, few studies have clarified exactly how these characteristics affect female mate preferences. here, we show that testo ...201829968815
neuromuscular anomalies following oral exposure to 3-nitro-1,2,4-triazol-5-one (nto) in a one-generation study with japanese quail (coturnix japonica).substances used as explosives in munitions by the military often result in environmental releases through manufacturing, testing, training, and combat activities. the toxicity of 3-nitro-1,2,4-triazol-5-one (nitrotriazolone or nto) was evaluated following oral exposure in japanese quail (coturnix japonica) to determine if environmental releases result in unacceptable risks to avian populations. in an acute test at the limit dose (2000 mg/kg), one female was ataxic, exhibited tremors, and showed ...201829939830
adrenocortical responses in japanese quail classified by their permanence in proximity to either low or high density of conspecifics.the density-related permanence test (drp) is used to classify young birds (while in groups) according to their individual permanence in proximity to either a high or low density of conspecifics (hd or ld, respectively). the birds' performance in drp was associated with underlying differences in the social responses of their individuals. quails in homogeneous groups of ld residents responded with less compact groups and higher levels of agonistic interactions to the presence of an intruder, and s ...201829924361
correction: social environment during egg laying: changes in plasma hormones with no consequences for yolk hormones or fecundity in female japanese quail, coturnix japonica.[this corrects the article doi: 10.1371/journal.pone.0176146.].201829889901
absence of gut microbiota reduces emotional reactivity in japanese quails (coturnix japonica).background: recent studies have demonstrated an effect of the gut microbiota on brain development and behavior leading to the concept of the microbiota-gut-brain axis. however, its effect on behavior in birds is unknown. the aim of the present study was to determine the effect of the absence of gut microbiota on emotional reactivity in birds by comparing germ-free (gf) quails to those colonized (col) with gut microbiota. material and methods: from hatching, the quails of both groups gf (n = 36) ...201829881357
a glucocorticoid receptor antagonist reduces sign-tracking behavior in male japanese quail.addiction is characterized as a chronic debilitating disease. one devastating feature of addiction is the susceptibility of relapse (40-60%) after stretches of abstinence. one theory that may account for relapse suggests that drug cues (e.g., paraphernalia) may increase stress hormones, and this may prompt relapse. repeatedly pairing a neutral cue with a reward is commonly utilized to measure what subjects learn about a cue that is predictive of reward. research has shown that animals that atten ...201829878800
in ovo yolk carotenoid and testosterone levels interactively influence female transfer of yolk antioxidants to her eggs.mothers can influence prenatal conditions by varying the amount of nutrients, hormones or antioxidants they provide to their developing young. some of these substances even affect the transfer of these compounds in the next generation, but it is less clear how different maternally transmitted compounds interact with each other to shape reproductive resource allocation in their offspring. here, we found that female japanese quails (coturnix japonica) that were exposed to high carotenoid levels du ...201829875206
neuroendocrine mechanism of food intake and energy regulation in japanese quail under differential simulated photoperiodic conditions: involvement of hypothalamic neuropeptides, ampk, insulin and adiponectin receptors.neuroendocrine coordination between the reproductive and energy regulatory hypothalamic circuitries not only tightly regulates food intake and energy expenditure but also maintains the body weight and reproduction. the effect of different simulated photoperiodic conditions on food intake and neuroendocrine mechanism of energy homeostasis in japanese quail is not investigated till date. hence, our present study is designed to elucidate the effect of different simulated photoperiodic conditions on ...201829857310
effect of distillery yeast sludge on growth performance, nutrient digestibility and slaughter parameters in japanese quails.this study was planned to evaluate the effect of distillery yeast sludge (dys) as a protein source on growth performance, nutrient digestibility and slaughtering parameters in japanese quail birds. for this purpose, six hundred day-old quails were randomly distributed into six dietary treatments. these dietary treatments were; g1 (control group) fed a basal diet (cp 24%, me 2900 kcal/kg) without dys, while other dietary treatments were g2, g3, g4, g5 and g6 fed basal diet containing dys @ 1.5, 3 ...201829849067
dietary supplementation of yucca schidigera extract enhances productive and reproductive performances, blood profile, immune function, and antioxidant status in laying japanese quails exposed to lead in the diet.the present study investigated the toxic impacts of lead (ld) on the productive and reproductive performances of japanese quails and the role of yucca schidigera extract (yse) in reducing these impacts. a total of 360 mature japanese quails (at 2 months of age) were used and the experiment was lasted for 8 wk. the birds were divided into 6 equal groups as follows: control (basal diet), basal diet + 100 mg ld/kg diet, basal diet + yse (100 mg/kg diet), basal diet + yse (200 mg/kg diet), basal die ...201829846703
use of acetylsalicylic acid as an allostatic modulator in the diets of growing japanese quails exposed to heat stress.the purpose of this study was to investigate the effect of dietary acetylsalicylic acid (asa) supplementation on performance, carcasses and some blood metabolites of growing quails exposed to heat stress. three hundred sixty mix sexed japanese quail chicks at 2 wk of age with average initial body weight of 77.4 g were randomly allotted to six dietary groups in a 3 × 2 factorial design with three dietary asa doses (0, 0.5 and 1 g asa/kg diet) and two ambient temperatures (one normal at 23 ± 2 °c ...201829801651
impact of estrogen and photoperiod on arginine vasotocin and vt3 receptor expression in the shell gland of quail.role of estrogen and photoperiod is well-established in avian reproduction. in addition, the distribution and the expression of arginine vasotocin (avt) and its receptor vt3 to ensure reproductive/breeding conditions in japanese quail influenced by them has been the main focus of this review. to consider this aspect the mrna expression of vt3 receptor and its ligand avt in the shell gland has been emphasized. in birds, avt performs a dual role as an anti-diuretic hormone and the functions accomp ...201829772564
correlation between objective semen analysis and fertility in japanese quail.this study investigated the relationship between sperm kinematics and egg fertility in japanese quail in an attempt to identify a semen trait that could be used to predict male fertility. males (n=45) and females (n=180) from five strains (a, b, c, d, e) were used. ejaculates (n=720) were collected from 8 to 38 weeks of male age. semen volume and sperm concentration were recorded and sperm motility was analyzed using sperm class analyzer (sca®-casa). at the time of ejaculate collection, males we ...201829704754
no evidence for sex-specific effects of the maternal social environment on offspring development in japanese quail (coturnix japonica).the social environment of reproducing females can cause physiological changes, with consequences for reproductive investment and offspring development. these prenatal maternal effects are often found to be sex-specific and may have evolved as adaptations, maximizing fitness of male and female offspring for their future environment. female hormone levels during reproduction are considered a potential mechanism regulating sex allocation in vertebrates: high maternal androgens have repeatedly been ...201829684400
identification of quantitative trait loci affecting production and biochemical traits in a unique japanese quail resource population.the objective of the current study was to identify qtl associated with body weight, growth rate, egg quality traits, concentration of selected blood plasma, and yolk lipids as well as concentration of selected macro- and microelements, color, ph, basic chemical composition, and drip loss of breast muscle of japanese quail (coturnix japonica). twenty-two meat-type males (line f33) were crossed with twenty-two laying-type females (line s22) to produce a generation of f1 hybrids. the f2 generation ...201829672744
effects of monochromatic light stimuli during embryogenesis on some performance traits, behavior, and fear responses in japanese quails.lighting is crucial in poultry rearing and the subjects with light intensity, source, and color having been addressed in numerous studies. numerous studies with monochromatic light from light-emitting diode (led) bulbs have been reported. in the current study, fertile japanese quail eggs were exposed to a dark environment (control) or monochromatic green (560 nm) and blue (480 nm) lighting throughout incubation. there were no significant differences in hatch weight, hatchability, total embryonic ...201829669004
body growth, intestinal morphology and microflora of quail on diets supplemented with micronised wheat fibre.1. particle size reductions of fibre-rich materials alter structure, functional and digestive properties. to determine the effects of using fibre as an additive in japanese quail rations on performance and gut physiology, a trial using micronised wheat fibre (mwf) at levels of 0.0, 5, 10 and 15 g/kg in feed was conducted. 2. growth rate and feed efficiency were significantly improved when diets contained mwf while feed intake was not affected by levels of the fibre. as mwf content increased, the ...201829620417
appetite-associated responses to central neuropeptide y injection in quail.the appetite-associated effects of neuropeptide y (npy) have been extensively studied in mammalian models. less knowledge exists for other vertebrate species including birds. the aim of this study was to determine the effects of central injection of npy on feeding behavior and hypothalamic physiology in 7 day-old japanese quail (coturnix japonica). during the light cycle, intracerebroventricular injection of 1.9 pmol, 0.5, and 1.0 nmol doses of npy did not affect food intake, 0.031 to 0.13 nmol ...201829573813
yucca schidigera extract modulates the lead-induced oxidative damage, nephropathy and altered inflammatory response and glucose homeostasis in japanese quails.the present study was conducted to explore the toxic effects of lead (pb) on the physiological responses of japanese quails and to investigate the potential modulatory role of yucca schidigera extract (yse) against these effects. 360 mature japanese quails (at 2 months of age) were used and the experiment was lasted for 8 weeks. the birds were divided into six equal groups as follow: control (basal diet, bd), bd+pb (100 mg/kg diet), bd+yse (100 mg/kg diet), bd+yse (200 mg/kg diet), bd+pb (100 mg ...201829571109
an overview of jatropha curcas meal-induced productive and reproductive toxicity in japanese quail: potential mechanisms and heat detoxification.the present study was carried out to investigate the toxic effects of dietary inclusion of raw jatropha cucas meal [rjm, 3.5%] on productive and reproductive performances of laying japanese quail and the influence of physical treatment of jatropha meal by heating at [100 oc] for 24 or 48 h [jh24 or jh48 respectively] on reducing these effects. the inclusion of rjm in quail diets significantly decreased the egg production, fertility and hatchability percentages and resulted in a high mortality ra ...201829554603
fermented soybean meal exhibits probiotic properties when included in japanese quail diet in replacement of soybean meal.this study was conducted to investigate and compare the effect of dietary probiotic mixture (pm) and organic acid (oa) mixture with fermented soybean meal (fsbm) on performance, crop, and ceca microbiota, small intestine morphology, and serum lipid profile in japanese quails. a total of 800 day-old japanese quails was randomly allotted to 5 treatments with 8 replicate pens of 20 birds each, for 35 days. the experimental diets consisted of a control corn-soybean meal diet and 4 test diets: 1) con ...201829554364
the hidden function of egg white antimicrobials: egg weight-dependent effects of avidin on avian embryo survival and hatchling phenotype.avidin is a key egg white antimicrobial protein with strong binding capacity for biotin, an essential growth and immune cell precursor. as such, it is assumed to have a pronounced, though still poorly explored, effect on hatchling phenotype. we tested the effect of experimentally increased egg white avidin concentration (avidin+) on hatching success, chick morphology, post-hatching growth performance and innate immune function in a model bird, japanese quail (coturnix japonica). probability of e ...201829540428
comparative effects of zinc oxide, zinc oxide nanoparticle and zinc-methionine on hatchability and reproductive variables in male japanese quail.the objective was to examine the effect of different dietary zinc sources on reproduction of male japanese quail. a total of 512 quail chicks (day-old) were divided into four groups with four replications for a period of 42 days. after this period, excess chicks were removed to attain the ratio of one male to three females and 16 quail in each subgroup. at 52 to 60 d of age, the eggs were collected and incubated. the basal diet (control) contained no zinc and the other three experimental diets w ...201829525207
gonadotropin-inhibitory hormone mediates behavioral stress responses.gonadotropin-inhibitory hormone (gnih) is an inhibitor of the hypothalamic-pituitary-gonadal (hpg) axis. gnih is also called rfamide-related peptide (rfrp) as gnih peptides have a characteristic c-terminal lpxrfiamide (x = l or q) sequence. gnih is thought to be the mediator of stress by negatively regulating the hpg axis as various stressors increase gnih mrna, gnih peptide or gnih neuronal activity. on the other hand, gnih may also mediate behavioral stress responses as gnih neuronal fibers an ...201829510150
functional morphology of thecal glands in the ovary of japanese quails (coturnix japonica).the role of thecal glands in the ovary of birds remains controversial. using transmission electron microscopy and immunohistochemistry, immunohistochemical localisation of cyclooxygenase i and ii (cox-1 and cox-2), oestrogen receptor α and β (er-α and er-β), androgen receptor (ar) and progesterone receptor (pr), a detailed analysis of the thecal glands was performed. our ultrastructural studies revealed that the thecal glands of the quail ovary consist of 2 cell types, steroid-producing cells (s ...201829495007
correction to: effect of chromium nanoparticles on physiological stress induced by exogenous dexamethasone in japanese quails.the original version of this article contained a mistake: the author name shokoufe ghazanfari was incorrectly written as shekofeh ghazanfari.201829492836
involvement of cholinesterases in oxidative stress induced by chlorpyrifos in the brain of japanese quail.chlorpyrifos is a widely used organophosphate pesticide (op). in birds and mammals op exhibits a toxic effect via inhibition of cholinesterases [acetylcholinesterase (ache) and butyrylcholinesterase (bche)] and through oxidative/nitrosative stress. in this study, the influence of chlorpyrifos on cholinesterase activity, parameters of oxidative stress [malondialdehyde (mda); glutathione (gsh); superoxide dismutase (sod); nitrite concentration (no2-); hydrogen peroxide (h2o2)], and inflammatory pa ...201829471505
differential control of appetitive and consummatory sexual behavior by neuroestrogens in male quail.contribution to special issue on fast effects of steroids. estrogens exert pleiotropic effects on multiple physiological and behavioral traits including sexual behavior. these effects are classically mediated via binding to nuclear receptors and subsequent regulation of target gene transcription. estrogens also affect neuronal activity and cell-signaling pathways via faster, membrane-initiated events. although the distinction between appetitive and consummatory aspects of sexual behavior has bee ...201829452074
effects of silver nanoparticles on hematological parameters and hepatorenal functions in laying japanese quails.silver nanoparticles (agnps) have recently emerged as a powerful agents for disinfection in the poultry industry. agnps are capable of epithelial barriers passing from the route of exposure to the vital organs and cells. this study evaluated the effects of agnps on organs weights, blood biochemical, hematological, and coagulation parameters, antioxidant enzyme activities, and histopathological changes and silver concentrations of liver and kidney tissues in laying japanese quails after exposure ...201829450680
antioxidant capacity of omega-3-fatty acids and vitamin e against imidacloprid-induced hepatotoxicity in japanese quails.imidacloprid (im) is a neonicotinoid insecticide, used in a wide range of agricultural activities worldwide. however, it results in ecosystem disturbances and signs of toxicity in human and animals. the current study was designed to elucidate the protective effects of omega-3-fatty acids (ofas) and vitamin e (vit e) against im hepatotoxicity in japanese quails. seventy male quails (30 days old) were divided into seven groups (n = 10); g1 -ve control; g2 received im (+ve control); g3 received ofa ...201829442305
interaction of genotype and diet on small intestine microbiota of japanese quail fed a cholesterol enriched diet.our previous study has shown that genetic selection for susceptibility/resistance to diet-induced atherosclerosis has affected the japanese quail's cecal environment to accommodate distinctly different cecal microbiota. in this study, we fed the atherosclerosis-resistant (res) and -susceptable (sus) quail a regular and a cholesterol enriched diet to examine the interaction of host genotype and diet on the diversity, composition, and metabolic functions of the duodenal and ileal microbiota with r ...201829402949
the role of cinnamon as a modulator of the expression of genes related to antioxidant activity and lipid metabolism of laying quails.since cinnamon has vitamins and minerals in addition to antioxidants compounds in its chemical composition studies have shown the potential of cinnamon supplementation on some important characteristics in the performance of birds. thus, this study was conducted under the hypothesis that the inclusion of cinnamon in the laying quail diet could influence the performance of the birds through the expression of genes related to antioxidant activity and lipid metabolism. to test this hypothesis, 144 j ...201729267351
simulated photoperiod influences testicular activity in quail via modulating local gnrhr-gnihr, gh-r, cnx-43 and 14-3-3.the hypothalamo-hypophyseal-gonadal axis mediated differential photosexual responses in quail kept under different simulated photoperiodic conditions have been studied in details. local testicular gnrh-gnih and their receptor system has been hypothesized to be modulated in quail showing different photo-sexual responses and thus influence the testicular activity and steroidogenesis through local (paracrine and autocrine) action. to validate this hypothesis, we studied the expression of gonadotrop ...201829197784
performance, carcass traits, meat quality and amino acid profile of different japanese quails strains.poultry production is considered one of the prospective opportunities to accomplish sustainable and quick production of superior protein to challenge the growing mandate for animal protein. therefore, this study was aimed to explore the difference on growth performance, carcass traits, meat quality and amino acid profile of different japanese quails strains. a total of 480 quail chicks of four different plumage colors (120 of each white, golden, gray and brown) were collected after hatching. at ...201729184224
expression of gonadotropin and sex steroid hormone receptor mrna in the utero-vaginal junction containing sperm storage tubules of oviduct during sexual maturation in japanese quail.sex steroid hormones play an important role in reproductive tissue development of avian species. however, their role in japanese quail is yet to be established. to understand the physiological role of hormones involved in the development of sperm storage tubules (ssts) in quail, we investigated expression profiles of gonadotropin (lh-r and fsh-r) and sex steroid hormone (pr-r, er-α and er-β) receptors in the uterovaginal junction (uvj) containing ssts before and during sexual maturation i.e. fou ...201829174868
embryonic cholesterol esterification is regulated by a cyclic amp-dependent pathway in yolk sac membrane-derived endodermal epithelial cells.during avian embryonic development, endodermal epithelial cells (eecs) absorb yolk through the yolk sac membrane. sterol o-acyltransferase (soat) is important for esterification and yolk lipid utilization during development. because the major enzyme for yolk sac membrane cholesteryl ester synthesis is soat1, we cloned the avian soat1 promoter and elucidated the cellular functions of soat1. treatments with either glucagon, isobutylmethylxanthine (ibmx), an adenylate cyclase activator (forskolin), ...201729161294
genes integral to the reproductive function of male reproductive tissues drive heterogeneity in evolutionary rates in japanese quail.early comparative genomics studies originally uncovered a nonintuitive pattern; genes involved in reproduction appeared to evolve more rapidly than other classes of genes. currently, the emerging consensus is that genes encoding reproductive proteins evolve under variable selective pressures, producing more heterogeneous divergence patterns than previously appreciated. here, we investigate a facet of that heterogeneity and explore the factors that drive male reproductive tissue-based heterogenei ...201829158338
in ovo transformation of two emerging flame retardants in japanese quail (coturnix japonica).tris(1,3-dichloro-2-propyl) phosphate (tdcipp) and dechlorane plus (dp) are two chlorinated, alternative flame retardants that have been found in wild birds and bird eggs. little is known about the fate and effect of these compounds in birds, especially during the vulnerable stages of embryonic development. to investigate the ability of birds to biotransform these compounds, an in ovo exposure experiment with japanese quail eggs was performed. quail eggs were injected in the yolk sac with 1000ng ...201829149662
analysis of various effects of abamectin on erythrocyte morphology in japanese quails (coturnix japonica).although previous studies have already confirmed the toxicological potential of abamectin (aba) in different experimental models (from invertebrates to vertebrates), almost nothing is known about the impacts the exposure to this pesticide can cause on birds. thus, the aim of our study is to investigate the cytotoxic effects on the erythrocytes of female japanese quails (coturnix japonica) exposed to low abamectin concentrations. in order to do so, three experimental groups were proposed: "contro ...201829127630
intramuscular route of administration increases potency in eliciting cocaine-induced behavioral sensitization.cocaine is the number one abused psychostimulant drug that reaches addiction criterion in the us. in animals, repeated administration of cocaine results in behavioral sensitization which is thought to represent adaptations in the mesolimbic dopamine neural circuitry, the reward pathway. cocaine-induced behavioral sensitization is evident in rodents and quail when cocaine is administered intraperitoneally (ip).201729104856
effect of chromium nanoparticles on physiological stress induced by exogenous dexamethasone in japanese quails.chromium (cr), as an essential trace element, plays a critical role in carbohydrate, protein, and lipid metabolism in animals. it has been suggested that the beneficial effects of cr increase by environmental stresses, which lead to greater cr effects on stressed animals. the objective of the present study was to evaluate the response of physiologically stressed japanese quails (coturnix japonica) to dietary chromium nanoparticle (nano-cr) supplementation. the stress was induced by adding dexame ...201829098543
improving growth performance and health status of meat-type quail by supplementing the diet with black cumin cold-pressed oil as a natural alternative for antibiotics.using antibiotics in poultry diets as growth promoters was reported to have harmful effects on consumers, so the current study was done to monitor the impact of dietary supplementation of antimicrobial black cumin oil (bco) on carcass traits, growth performance, biochemical components, and ileal microbial populations of growing japanese quails. three hundred growing japanese quails were used with three different treatments (0, 0.50, and 1.0 g bco/g diet). birds fed diet supplemented with 0.5 g b ...201829079983
2-hydroxy-4-methylthio butanoic acid and dl-methionine for japanese quails in production.an experiment was performed using 1,000 laying japanese quails to assess the availability of two alternative dietary methionine sources. treatment 01 = basal feed that is deficient in digestible methionine + cystine (met + cys). the other treatments were constituted by met + cys levels of 0.8, 1.60 and 2.40 g/kg, supplemented with dl-methionine-99%, hmtba-88% and hmtba-84%, being 10 treatments in total. the following characteristics were studied: feed intake (g/bird/day), egg production (egg/day ...201829072374
protective effect of melatonin on lps-stimulated granulosa cells in japanese quail.the aim of this study was to evaluate the potential of melatonin to protect cultured granulosa cells from the harmful effects of lipopolysaccharide (lps) in quail. granulosa cells isolated from japanese quails were pretreated with or without melatonin (10 or 100 µg/ml) for 12 hand then incubated for 12 hin the absence or presence of 100 ng/ml lps. the expression of pro-inflammatory cytokines and chemokine was detected by quantitative real-time pcr. the levels of oxidative stress biomarkers (dity ...201732908443
melatonin does not affect progesterone basal secretion but suppresses the luteinizing hormone receptor expression in granulosa cells of the japanese quail.the aim of this study was to evaluate the potential effect of melatonin on progesterone production by granulosa cells of the japanese quail. for in vitro experiments, granulosa cells were isolated from pre-ovulatory follicles (f1-f3) when the f1 follicles were predicted to be either immature or mature (at 3-6 or 18-21 h after oviposition, respectively). granulosa cells were cultured for 12 hwithor without melatonin concentration gradients of 0.0001-100 µg/ml, thereby averting luteinizing hormone ...201732908442
unexpected results when assessing underlying aggressiveness in japanese quail using photocastrated stimulus birds.aggressive behaviors can affect both animal welfare and productivity. because the expression of aggressive behaviors is dependent on the quality of the opponent, they reflect relative rather than absolute levels of underlying aggressiveness. this study was aimed to characterize the aggressive responsiveness of photostimulated (14:10 h light:dark photoperiod) adult japanese quail when interacting with a photocastrated (6:18 h light:dark photoperiod) counterpart in a novel test environment and to ...201729053859
quail (coturnix japonica) egg yolk bioactive components attenuate streptozotocin-induced testicular damage and oxidative stress in diabetic rats.the testicular milieu is the machinery for the metabolism of testosterone in the male reproductive system.201829052001
estimation of lysine requirements for growing japanese quails.this study was conducted to estimate the lysine requirements of growing meat-type japanese quails based on different growth responses using different regression models. experimental treatments including five doses of dietary lysine (9.40, 10.9, 12.4, 13.9 and 15.4 g/kg of diet) were used in a dose-response platform from 7 to 21 day of age. a total of 375, 7-day old quail chicks were randomly allotted to one of five dietary treatments with five replicate pens and 15 birds per pen. performance tra ...201828986922
hormonal responses to a potential mate in male birds.social interactions rapidly modulate circulating hormone levels and behavioral patterns in most male animals. in male birds, sexual interaction or visual exposure to a conspecific female usually causes an increase in the levels of peripheral reproductive hormones, such as gonadotropins and androgens. although the perception of a female presence is processed in the brain and peripheral hormonal levels are regulated by the hypothalamus-pituitary-gonadal (hpg) axis, the specific neural circuitry an ...201728980234
divergent artificial selection for female reproductive investment has a sexually concordant effect on male reproductive success.depending on the genetic architecture of male and female fitness, sex-specific selection can have negative, positive, or neutral consequences for the opposite sex. theory predicts that conflict between male and female function may drive the breakdown of intrasexual genetic correlations, allowing sexual dimorphism in sexually antagonistic traits. reproductive traits are the epitome of this, showing highly differentiated proximate functions between the sexes. here we use divergent artificial selec ...201730283651
egg envelope glycoproteins zp1 and zp3 mediate sperm-egg interaction in the japanese quail.fertilization is indispensable for zygotic formation leading to the birth of animals and the species-specific sperm-egg binding thought to be the initial step in this important process. in birds, the oocyte, which encounters the spermatozoa at the time of fertilization, is enclosed in a perivitelline membrane (pvm) constructed of several zona pellucida glycoproteins (zp proteins: zp1, zp2, zp3, zp4 and zpd). the aim of this study was to determine the zp protein in the pvm responsible for sperm-p ...201732908412
effects of a protein kinase inhibitor on sperm motility in the japanese quail.sperm motility is an essential trait for successful fertilization in animals. in birds, ejaculated sperm migrate into sperm storage tubules before fertilization and are stored in a quiescent state. we previously reported that this type of sperm's flagellar quiescence was induced by lactic acid through flagellar dynein atpase inactivation following cytoplasmic acidification (<ph 6.0). however, signal transduction in the sperm cells leading to motility inactivation is not well understood. the aim ...201732908411
expression of prolactin receptor on the surface of quail spermatozoa.prolactin receptor (prlr) is expressed in a wide variety of tissues and mediates diverse biological actions of prolactin (prl). in mammals, prl signaling is thought to be involved not only in the process of spermatogenesis and steroidogenesis in the testis, but also in the survival of ejaculated sperm. in avian species, although the expression of prlr with several variants in the testis was reported, the role of prl in testicular function is still unclear. the aim of this study was to examine th ...201632908379
different photoperiodic responses in four lines of japanese quail.organisms measure day length to better adapt to seasonal changes in the environment; this phenomenon is called photoperiodism. the japanese quail has a highly sophisticated photoperiodic mechanism and is an excellent model for the study of photoperiodism. various lines of quail have been established during the domestication process. in the present study, we examined the effect of long day (ld) followed by short day (sd) on testicular weight in four lines of quail (l, amrp, nies-br, and we). when ...201632908366
interrelationships between morphological, densitometric and mechanical properties of eggs in japanese quails (coturnix japonica).eggshell quality in birds results from mineral density and composition determining its mechanical endurance. the aim of the study was to determine interrelationships between morphological, densitometric and mechanical properties of eggs in japanese quails. twenty four eggs randomly collected from 17-week-old quails were subjected to morphological, denstiometric and mechanical evaluation using dual-energy x-ray absorptiometry (dexa), quantitative computed tomography (qct) and three-point bending ...201632908364
viral metagenomic analysis of japanese quail (coturnix japonica) with enteritis in the republic of korea.we performed viral metagenomics analysis of japanese quail affected with enteritis to elucidate the viral etiology. metagenomics generated 21,066,442 sequence reads via high-throughput sequencing, with a mean length of 136 nt. enrichment in viral sequences suggested that at least three viruses were present in quail samples. coronavirus and picornavirus were identified and are known as pathogens causing quail enteritis that match the observed morphology. abundant reads of coronavirus from quail s ...202134339120
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