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dna damage measured using the alkaline elution assay depends on time between subculturing of cells and irradiation.in experiments utilizing the alkaline filter elution assay for radiation-induced dna damage we observed an unexpected dependence of hypoxic dose-response curves on the length of time v79 cells were in exponential growth between subculturing and irradiation. dose-response curves for dna from cells irradiated in air were identical regardless of whether the exponential-phase cells had been subcultured 24 or 48 h prior to irradiation, but cells irradiated in hypoxia 24 h after subculture displayed a ...20143952272
[gingival modifications during treatment with sodium phenytoin]. 20154509608
[darier-ferrand tumor]. 20164988056
[industrial medicine in the ural after abolition of serfdom]. 20164936090
plasma levels of d-amphetamine in hyperactive children. serial behavior and motor responses.amphetamine has been clearly documented to be an efficacious treatment for hyperactive children. the pharmacokinetics of amphetamine have been studied in adults, but not in children. sixteen male children who scored greater than 2sd from norms on factors i and iv of conner's teacher rating scale and who were not excluded for reasons to do with medical or psychiatric conditions, intelligence, or age, had a plasma d-amphetamine apparent elimination half-life of 6.8 +/- 0.5h. peak plasma level occu ...2000111276
studies of immune functions of patients with systemic lupus erythematosus. i. dysfunction of suppressor t-cell activity related to impaired generation of, rather than response to, suppressor cells.t cell suppressor function in patients with systemic lupus erythematosus (sle) was evaluated by studying the ability of concanavalin a- (con a) activated t cells to suppress proliferative responses by responder cells autologous with the con a-activated t cells. impaired suppressor t-cell activity in patients with sle was observed with regard to three effector functions: 1) the allogeneic response of t cells, 2) the con a response of t cells, and 3) the b cell response to pokeweed mitogen (pwm). ...2003153749
ca 72-4 radioimmunoassay in the diagnosis of malignant effusions. comparison of various tumor markers.we evaluated the utility of the ca 72-4, cea, ca 125, ca 19-9 and ca 15-3 radioimmunoassays for the detection of tumor-associated antigens (taas) in effusions of malignant vs. benign origin. fluids were obtained from 51 patients with adenocarcinomas, 27 with non-epithelial malignancies, and 68 with benign disorders. the ca 72-4 radioimmunoassay (cut-off value 8.5 u/ml) detected the tag-72 antigen in 51% of adenocarcinoma patients' effusions, while only 1 of 68 benign specimens had an elevated ta ...20072394511
latest figures on aids. 20113133045
dental health survey of gilbert and ellice islanders. 20144381043
dental health survey of gilbert and ellice islanders. 20144381043
marine and estuarine pollution. 20164914106
scanning electron microscopy of drosophila melanogaster embryogenesis. iii. formation of the head and caudal segments. 1998108157
chido, rodgers, and c4 deficiency. 199993815
evaluation of suspected deep venous thrombosis in the arteriosclerotic patient. 200099010
maternal and neonatal risk at caesarean section. 200015786
causal analysis of family resemblance. 2004534543
mucin-producing cells and endocrine cells of gallbladder epithelium in patients with uncomplicated cholelithiasis.in this study we have investigated various morphofunctional features of gallbladder mucosa in patients with uncomplicated cholelithiasis. the histological changes, endocrine cell types and their distribution, and mucin-producing cells were characterized by immunocytochemistry and mucin histochemistry; moreover, we attempted to correlate these findings to the number and size of gallbladder stones and the type of bacteria present in the bile. our results indicate that, despite similar clinical par ...20061855773
mucin-producing cells and endocrine cells of gallbladder epithelium in patients with uncomplicated cholelithiasis.in this study we have investigated various morphofunctional features of gallbladder mucosa in patients with uncomplicated cholelithiasis. the histological changes, endocrine cell types and their distribution, and mucin-producing cells were characterized by immunocytochemistry and mucin histochemistry; moreover, we attempted to correlate these findings to the number and size of gallbladder stones and the type of bacteria present in the bile. our results indicate that, despite similar clinical par ...20061855773
therapeutic considerations in the podiatric care of ulcerations.in this excellent article, dr. mccarthy presents some of the most current concepts in the treatment of lower extremity ulcerations. this common clinical finding is frequently frustrating and difficult to treat effectively. it also requires a high degree of suspicion as to the primary underlying cause and many hours of careful treatment and follow-up to prevent serious secondary complications, such as infection and gangrene. the emphasis on therapeutic approaches lends much useful information in ...20082427183
a child with phenotypic laron dwarfism and normal somatomedin levels. 20092725626
why does placebo improve severe limb ischaemia? 20102893161
[congenital malformations of the female genital tract and gestation capacity]. 20113232910
high progesterone/estradiol ratio in follicular fluid at oocyte aspiration for in vitro fertilization as a predictor of possible pregnancy.eighteen women undergoing in vitro fertilization (ivf) procedures were studied. all had optimal (900 to 1600 pg/ml) peak serum estradiol (e2) response to the same stimulation regimen with clomiphene citrate and menotropins; fertilization rate was above 64%; and two to four embryos in two to eight cell stages were replaced in each patient. all were considered to have optimal chances for conception. the authors compared progesterone (p), e2, and p/e2 ratio in serum and follicular fluid (ff) at the ...20113131157
the first international standard for antibodies to double stranded dna.this paper announces the availability of the first international standard for anti-double-stranded dna (anti-dsdna). the material, coded wo/80, was obtained after recalcification of plasma taken from a patient with systemic lupus erythematosus. vials were filled with 500 microliters serum and freeze dried. the serum contains no other autoantibodies in measurable quantities. the vials should be stored at -20 degrees c. the standard should be used for establishing national, regional, or local stan ...20113052322
the institutionalization of geriatrics. 20133782705
basal hypersecretion of cortisol in relation to abnormal dexamethasone suppression test response in depression.the activity of the hypothalamus-hypophysis-adrenal axis was evaluated in a group of patients with primary affective disorder by correlation of basal cortisol hypersecretion and abnormal response to dexamethasone suppression test (dst). the increase in basal cortisol was not found to be responsible for suppression failure. moreover, this biochemical abnormality was common in the groups of psychiatric patients studied, although the physiopathologic mechanisms involved are different. further resea ...20133809524
influence of conspecific males on the oestrous cycle of underfed female mice.female mice maintained on restricted diet (3.5, 3.0 and 2.5 gm/female/day) exhibited disturbances in the oestrous cycle which were directly related to the degree of diet restriction. females maintained on restricted diet, 2.5 gm/day, showed complete suppression of the oestrous cycle. the presence of a conspecific male was effective in maintaining normal oestrous cycles in underfed females to some extent. it is suggested that the ability of males to maintain oestrous cycle in underfed females is ...20144054221
[is tetracycline treatment of respiratory tract infections still appropriate?]. 1998108568
[vectorcardiographic studies of left ventricular loading (2)--changes of qrs loop with the development of hypertension]. 2000152363
post-traumatic epilepsy. 200198198
aluminum exposure and toxicity. 20062515266
present status of research abroad concerning the effect of acupuncture and moxibustion on immunologic functions.japan is one of the countries that have done extensive research on the effect of acupuncture and moxibustion on the immunologic functions. with china first, japan ranks second among the countries in this study. concerning research in this field concerned the level abroad can scarcely reach that in china. scholars abroad fail to base their research on tcm theory. in addition not only the type of diseases studied, and the indexes observed are far less than those in china, but also the scope of the ...20061453763
inhibition of trypsin by t-butyloxycarbonyl-alpha-aza-(4-aminophenyl)alanine phenyl ester.t-butyloxycarbonyl-alpha-aza-(4-aminophenyl)alanine phenyl ester (iii: r = nh2) has been synthesized. the rate of inhibition of trypsin (ec 3.4.21.4) by this compound (due to acylation followed by slower deacylation) shows a marked ph maximum at approximately 6. the shape of the ph-rate curve is discussed in terms of (i) the normal ph-activity curve of trypsin reacting with a charged substrate, i.e. the protonated form of the amino compound, (ii) the deprotonation of the 4-amino group with pka 4 ...20061367228
preventing nervous system sports injuries.physical fitness and sports remain integral components of overall good health and a cornerstone of preventive medicine. when performed safely, under adequate supervision, and with appropriate protective gear, most of these activities are enjoyable, healthful and psychologically gratifying. when not performed safely by trained athletes, these same activities can be treacherous, injurious and permanently disabling. the goals of this article are to review and describe low-risk and high-risk sports ...20082648209
preventing nervous system sports injuries.physical fitness and sports remain integral components of overall good health and a cornerstone of preventive medicine. when performed safely, under adequate supervision, and with appropriate protective gear, most of these activities are enjoyable, healthful and psychologically gratifying. when not performed safely by trained athletes, these same activities can be treacherous, injurious and permanently disabling. the goals of this article are to review and describe low-risk and high-risk sports ...20082648209
conversion of oa-6129 b2 into (5r,6r)-6-[(r)-1-fluoroethyl]-7-oxo-3-[(n,n,n'-trimethyl-carbamimidoyl methyl]thio-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid (88617). 20092808140
long-term bone marrow cultures: recent studies with clonal hematopoietic and stromal cell lines. 20092785687
[effect of thymosin on afferent transmission in the somatosensory system of macaca rhesus]. 20103030681
[effect of thymosin on afferent transmission in the somatosensory system of macaca rhesus]. 20103030681
the molecular and fibrillar structure of collagen and its relationship to the mechanical properties of connective tissue.the conformation of type i collagen molecules has been refined using a linked-atom least-squares procedure in conjunction with high-quality x-ray diffraction data. in many tendons these molecules pack in crystalline arrays and a careful measurement of the positions of the bragg reflections allows the unit cell to be determined with high precision. from a further analysis of the x-ray data it can be shown that the highly ordered overlap region of the collagen fibrils consists of a crystalline arr ...20103282560
[content of ldh isoenzyme and immunoglobulin in tears of patients with epidemic hemorrhagic conjunctivitis]. 20113148425
glycoprobe fructosamine kit used with the rotochem cfa 2000 centrifugal analyzer. 20123416449
laryngeal trauma vs length of intubation.the frequency histograms of six patients' laryngographs were studied pre- and post-endotracheal intubation. the changes were correlated with the length of intubation. the post-operative hoarse voice was seen as an increase in the spread of the lower frequencies, and an increase in the fundamental frequency. the latter change was thought to be a subconscious compensation for the hoarseness. the increased lower frequency spread as measured by standard deviation was directly proportional to the len ...20133694032
synthesis of 12-mono- and di-substituted 8-aza-11-oxasteroids.the synthesis of unsaturated derivatives of 8-aza-11-oxa-17-oxo-gonane and d-homo-gonane carrying one or two functional substituents at c-12 is reported. the key step for the construction of the heterosteroid skeleton was the cyclocondensation reaction of aldol adducts 1, derived from 1,3-cycloalkanediones and diethyl 2-oxo-malonate, with tosyl chloride and isoquinoline.20133590241
letter: the "territorial domain" of hemoptysis. 20154832279
letter: the "territorial domain" of hemoptysis. 20154832279
gene dosage in a deletion for a nuclear-coded, mitochondrial enzyme. 20164823666
[hemorrhagic glaucoma following central retinal vein thrombosis]. 20164822128
[cephalosporins. ii]. 2000305836
assessment of a patient-held minirecord for adult health maintenance. 20052212976
the therapeutic role of octreotide in the management of surgical disorders.the long-acting somatostatin analogue, octreotide, has recently been made available for clinical use in the united states. this novel synthetic peptide possesses a broad spectrum of physiologic actions primarily involving the inhibition of a variety of gastrointestinal and endocrine functions. such actions have been utilized in the management of a variety of surgical disorders. current understanding of the indications and efficacy of this agent in the treatment of surgical disease is reviewed.20071951921
the association of specific "favorable" cytogenetic abnormalities with secondary leukemia.eight patients with secondary leukemia and specific cytogenetic abnormalities involving inversion of chromosome 16, or translocations between chromosomes 15 and 17, or 8 and 21, are presented. seven of them (87%) achieved complete remission with chemotherapy. the occurrence of these karyotypes, which is unusual in secondary leukemia, and the favorable response to chemotherapy are discussed in relation to the pathogenesis of the disease.20133719557
contribution of ct scan to the diagnosis of fahr's syndrome.of 7040 patients who were examined with ct scan for various reasons, 72 (1.02%) showed symmetrical intracranial calcifications. on the basis of the extent of the calcifications, the patients were divided into 3 groups of which the first (10 cases), with extensive calcifications, showed clear findings of hypoparathyroidism; the second (4 cases), with less extensive calcifications, showed borderline laboratory findings and the third (58 cases), with calcifications only in the internal part of the ...20143993326
mass culture of mammalian cells as a national project. 20061367250
[acute pancreatitis: fluid accumulation in the lesser omental sac and retroperitoneum]. 20113563061
preoperative condition of neonates who have ultimately died.in a retrospective study the case sheets of 42 neonates are examined. they were infants with oesophageal atresias, small and large intestinal atresias, exomphalos and gastroschisis, diaphragmatic hernia, intestinal obstruction as well as two children with a ruptured spleen secondary to birth trauma. various laboratory investigations such as the ph, pco2, standard bicarbonate and serum electrolytes as well as the child's weight on admission and, if possible, the birth weight were evaluated. there ...1994523638
the reconstruction of schizophrenic speech.a suggestion that schizophrenic speech may be harder to understand than normal speech was tested by a technique of reconstruction. ten schizophrenic and ten normal passages were typed onto cards, one sentence per card. each passage was then presented with the sentences in random order, and students were asked to reconstruct what they believed was the original order. fewer correct strings of three or more sentences were achieved for the schizophrenic material than the normal material. it is concl ...2004444785
intrathecal administration of 131i radiolabelled monoclonal antibody as a treatment for neoplastic meningitis.fifteen patients with neoplastic meningitis received a single intrathecal injection of between 11 and 60 mci of a 131i radiolabelled monoclonal antibody (moab), chosen for its immunoreactivity to tumour. major toxicity was manifest as nausea, vomiting and headache (7/15 patients), reversible bone marrow suppression (3/8 patients) and seizures (2/15 patients). nine patients were evaluable for either a tumour or clinical response. six of these demonstrated an event-free response that was maintaine ...20072223581
intrathecal administration of 131i radiolabelled monoclonal antibody as a treatment for neoplastic meningitis.fifteen patients with neoplastic meningitis received a single intrathecal injection of between 11 and 60 mci of a 131i radiolabelled monoclonal antibody (moab), chosen for its immunoreactivity to tumour. major toxicity was manifest as nausea, vomiting and headache (7/15 patients), reversible bone marrow suppression (3/8 patients) and seizures (2/15 patients). nine patients were evaluable for either a tumour or clinical response. six of these demonstrated an event-free response that was maintaine ...20072223581
effect of macrophages on interleukin-2 (il-2)- and il-4-induced murine lymphokine-activated killer activity.the enhancing effect of macrophages on interleukin-2 (il-2)- and il-4-induced murine lymphokine-activated killer (lak) activity was investigated in this study. peritoneal macrophages significantly enhanced lak activity generated from accessory cell-depleted splenic lymphocytes in both il-2 and il-4 cultures. this effect was dependent on the number of macrophages and was not replaced by a factor derived from macrophages or lymphocytes. macrophages enhanced il-2- and il-4-induced lak activity agai ...20072045201
oral contraception and post-operative thromboembolism: an epidemiological review.it has been stated that oestrogen-containing oral contraceptive medication should be discontinued one month prior to surgery, to avoid an increased incidence of post-operative thromboembolism. others have suggested that the risk of post-operative morbidity is low compared with the risk of pre-operative pregnancy, and that in most cases no such action should be taken. the evidence from clinical investigation is reviewed, with particular reference to study design. it is found that all studies so f ...20092698507
[results of a randomized polychemotherapy study in malignant melanoma].a polychemotherapy (dtic, vincristine, ftorafur, hydroxycarbamide) devised with reference to the results of short-term sensitivity tests in cell culture is compared with single-agent chemotherapy with dtic in malignant melanoma. effectiveness was investigated in a randomized prospective study in cases of high-risk melanoma in clinical stage i, in clinical stage ii after lymphadenectomy and in clinical stage iii after tumour debulking. the results recorded allow no positive effects of either form ...20061698185
nutrition in cryptogenic cirrhosis and chronic aggressive hepatitis.the nutritional status of 80 patients with non-alcoholic chronic liver disease was assessed by determination of various nutritional parameters in body fluids. with the exception of vitamin c there was a higher incidence (40%) of fat soluble vitamin deficiency (vitamins a, e, and carotene) than of the water soluble vitamins. less than 10% of patients showed evidence of vitamin b12, nicotinic acid, thiamin, or riboflavin deficiency, and 17% had evidence of folic acid deficiency. the presence of de ...2002131055
echocardiography of the tricuspid valve in congenital left ventricular-riht atrial communication.two patients, ages 14 and 18, with congenital left ventricular-right atrial communication through a defect in the tricuspid valve were studied by echocardiography. proof was obtained by angiocardiography and surgery in one and ultrasonic contrast injection and angiocardiography in the other. both presented clinically as uncomplicated ventricular septal defects. echocardiography consistently demonstrated a high frequency, low amplitude flutter of the tricuspid valve in systole and none in diastol ...20051112006
[malabsorption syndrome (classification and diagnosis)]. 1998107557
[pulmonary capillary pressure and the exercise test].in the present work with radiocardiography the change of pulmonary capillary pressure as well as cross correlations of stroke index, cardiac index, pulmonary blood volume, pulmonary arterial pressure and pulmonary dispersion volume which reflects pulmonary capillary volume have been studied during muscular exercise. with increase in cardiac output the mathematical estimation showed decrease in pulmonary capillary pressure while stroke index, pulmonary blood volume and pulmonary dispersion volume ...1998107894
eating difficulties in patients with probable dementia of the alzheimer type.seventy-three institutionalized patients suffering from probable dementia of the alzheimer type (dat) were surveyed for the presence of eating difficulties. among 71 patients fed by natural means four different groups emerged: (1) patients who fed themselves (n = 17, 23.9%), (2) patients who had to be fed but posed no other eating problem (n = 13, 18.3%), (3) patients who refused food although they were able to swallow it (n = 18, 25.4%), and (4) patients who choked on liquid and/or solid food, ...20082483945
the inspiring promise of dental implantology. 20092704492
[treatment of duodenogastric and gastroesophageal reflux]. 20123420918
head and neck malignancies in children: an age-incidence study.one hundred forty-seven (147) children under 18 years have been treated for head and neck malignancies at texas children's hospital from 1970 to 1985 and form the data base for this study. in order of frequency, the most common tumors were lymphoma, langerhans' histiocytosis (lh), rhabdomyosarcoma, neuroblastoma, and other soft-tissue sarcoma. children under 2 were most likely to have lh; those from 3 to 5, lh or lymphoma; and those over 5, lymphoma.20123257285
congestive heart failure and jaundice following replacement of cardiac valves. 20165089854
[liver diseases and glycoregulation]. 20133811778
possible mechanism of antidepressant effect of l-sulpiride.l-sulpiride is a dopamine (da)-receptor blocker that acts as an antidepressant at low doses. we have reviewed evidence suggesting that the antidepressant effect of l-sulpiride may depend on the activation of da transmission secondary to the blockade of da autoreceptors.19972199037
balloon catheter to control transhepatic obliteration of gastroesophageal varices. 1998106700
intracellular symbiont as a major source of the ribosomal rnas in the aphid mycetocytes. 199996827
[long term disodium-cromoglycate treatment in children with bronchiale asthma who responded unsatisfactorily to hyposensitation (author's transl)].the authors treated 53 asthmatic children for 1/2 to 2 years with disodium-cromoglycate (intal). the patients were selected of 412 children suffering of bronchial asthma. the patients were living at home and controled by the outpatient consultation of the hospital. the criteria of selection were: 1. failure of hyposensitization-treatment, or symptomatic therapy. 2. polysensibilisation. 3. anaphylactic shock. 4. lack of positive skin tests to allergen extracts ("endogenous asthma"). 40 patients g ...200097517
the results of basal and post pentagastrin gastric secretory studies in apparently healthy subjects, a preliminary communication.pentagastrin stimulated gastric secretory studies were carried out in 26 apparently healthy subjects. each specimen of gastric juice was analysed for volume, ph, total acidity and major electrolytes. the data was analysed and compared with other published reports.200097409
chemosensory responses of swimming algae and protozoa. 200097241
letter: gluten-sensitive polymyositis and enteropathy. 200159890
t-cell lymphoma after heart transplantation.a 26-year-old woman who had undergone orthotopic heart transplantation because of dilative cardiomyopathy received a triple-drug immunosuppressive regimen (cyclosporine a, azathioprine, and prednisolone). during her relatively frequent episodes of acute rejection, she was treated with methylprednisolone and repeated application of atg. a short time before the patient's death, a fine-needle aspiration of the liver revealed the cytologic diagnosis of a malignant pleomorphic medium-size cell non-ho ...20012193510
significance of animal play. 2004412172
effect of age on ibuprofen pharmacokinetics and antipyretic response.the effect of age on ibuprofen pharmacokinetics and antipyretic effect was studied in 49 infants and children aged 3 months to 10.4 years. the relationship of plasma concentration to antipyretic effect was examined in 38 of the children by using an iterative least squares technique that allows estimation of drug concentration with time in a theoretical effect compartment and rate constant for elimination of drug from the effect compartment. there was a delay of 1 to 3 hours between peak ibuprofe ...20061447669
[new knowledge about the stomach and nutrition]. 20072063589
[hemodialysis and urea kinetics. an elementary computational program].an elementary computational program to optimize dialysis in children with chronic renal failure was developed. the program is based on the urea kinetics model. parameters involved in the efficiency of hemodialysis such as time and clearance, hemofilter performance and body surface area, as well as nutritional needs of the child are considered in the program.20082519449
life before medline: myasthenia gravis, muscular dystrophy, and myasthenic myopathy. 20082679505
the processing of spatially transformed text.the present study shows that previous attempts to demonstrate explicit memory for orientation of spatially transformed text were inconclusive. in the present experiments, subjects read spatially transformed sentences and were then given a recognition test that permitted the use of only nonsemantic information. the results revealed clear evidence of incidental retention of nonsemantic information on an immediate test, no improvement in performance under intentional learning conditions, reduced bu ...20092725265
expression of normal myeloid-associated antigens by acute leukemia cells.monoclonal antibodies that react with hematopoietic cells and their precursors in a stage and lineage restricted fashion were used in indirect immunofluorescence assays to examine leukemic cells from 105 pediatric age patients. the differentiative states of blasts from 42 patients with acute nonlymphocytic leukemia (anll) were defined by these antibodies. when these were compared to their morphologic and histochemical levels of differentiation as defined by the french-american-british (fab) clas ...20102937468
development of training programmes in biotechnology safety and risk assessment. 20113228452
autotransplantation of maxillary canine teeth. a follow-up of 35 cases up to 4 years.35 cases of autotransplantation of nonendodontically treated maxillary canines were followed for up to 4 years and were assessed according to loss of the transplanted tooth, onset of sensibility, mobility, intact lamina dura and presence of tooth resorption. the results of this study compare favourably with other studies and favour the hypothesis that little is to be gained by not endodontically treating autotransplanted teeth immediately after splint removal. it is also suggested that immobiliz ...20113088156
liposarcoma in a canada goose (branta canadensis).a multicentric liposarcoma was identified in various skeletal muscles of a mature canada goose. the light and electron microscopic appearance of the tumor is discussed in relation to the appearance of liposarcoma in other species.20123442545
suspended scaffolding: proper protection reduces fall injuries. 20123347448
a.i.d. and aids--too close for comfort. 20123338577
primary malignant tumors of the liver. 20124321901
[barbituric acid derivatives. 38. enantio-specific synthesis for enantiomers of barbiturates with a basic side chain on nitrogen]. 20133675167
developmental abnormalities in the chemically dependent newborn. 20133647988
anatomy and electrophysiology of neurons terminating in the corpora allata of the cockroach diploptera punctata.intracellular recording and dye injection were used to study the structure and electrophysiological properties of individual neurons that project to the corpora allata of the cockroach, diploptera punctata. neurons in the pars intercerebralis generate long-duration, tetrodotoxin-sensitive action potentials. dye injection revealed two cell types. one type extends axons to the contralateral nervi corporis cardiaci i, some of which innervate the corpora allata, and another type extends a major axon ...20133624539
relation between gm(f) and the structure of the gamma-globulin molecule. 20144160245
[elbow dislocation complicated by diaphyseal fracture of the radius]. 20144147862
description and classification--the cornerstones of pathokinesiological research. 20143952155
the amplification of recoil particle tracks in polymers and its application in fast neutron personnel dosimetry. 20154436068
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