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randomized, double-blind comparative study of intravenous ciprofloxacin versus ceftazidime in the treatment of serious infections.we compared intravenously administered ciprofloxacin with ceftazidime in a randomized, double-blind study. patients received ciprofloxacin 200 mg intravenously every 12 hours or ceftazidime 2 g intravenously every eight hours, with placebo infusions to maintain blinding. therapy with metronidazole was added for suspected or documented intra-abdominal infection. thirty-two of the 57 ciprofloxacin-treated patients were evaluable for determination of efficacy and had 41 bacterial isolates from 34 s ...19892686416
intravenous ciprofloxacin and ceftazidime in serious infections. a prospective, controlled clinical trial with third-party blinding.oral ciprofloxacin has been shown to be effective in the treatment of infections due to gram-positive cocci and gram-negative rods. the efficacy and safety of intravenous ciprofloxacin was compared with that of intravenous ceftazidime in the treatment of 59 patients with well-documented serious infections in a prospective, controlled, randomized study with a third-party blinding. thirty-three patients were treated with intravenous ciprofloxacin (200 mg every 12 hours, plus a daily extra placebo ...19892686425
[perinephric phlegmon. current aspects of diagnosis and treatment. apropos of 20 cases].the authors report a series of twenty patients presenting with perinephric abscess. percutaneous management was performed in 4 cases. considering the benefit of the modern imaging techniques, the authors discuss the current diagnostic, therapeutic and prognostic modalities of this disease.19892686539
disseminated klebsiella rhinoscleromatis infection.a 35-year-old obese black american woman presented with nausea, vomiting, diarrhea, fever, cough, and chest pain of 2 weeks duration. she was pancytopenic and acidotic, with respiratory failure and hypotension. a diagnosis of septic shock was made, and the patient died 48 hours after admission. blood cultures were positive for organisms that were reported to be klebsiella rhinoscleromatis. at autopsy she had massive hepatic necrosis with numerous mikulicz's cells. the lungs, spleen, and bone mar ...19892686580
therapeutic effect of aspoxicillin on experimental pneumonia with klebsiella pneumoniae in mice.the therapeutic effects of aspoxicillin (aspc) on an experimental pneumonia in mice were compared with those of piperacillin (pipc) and mezlocillin (mzpc) under various administration schedules. the pneumonia was induced with k. pneumoniae b-54 by the aerosol method. fifty mg/kg of each penicillin was subcutaneously injected into mice starting from 12 h after infection. at 3- and 6-h interval regimens, aspc caused the infected mice to survive longer than the other penicillins. the decrease of vi ...19892686954
association of r plasmids of klebsiella pneumoniae with resistance to heavy metals, klebocin and beta lactamase production and lactose fermentation.one hundred and fifty clinical isolates of klebsiella pneumoniae were studied for beta lactamase production, klebocin production and resistance to antibiotics and metals. 97.3 and 82.7 per cent strains produced beta-lactamase and klebocin respectively. resistance to arsenite, antimony, tellurite, mercury and silver was observed in 91,66,6, 47.7, 44.8 and 33.3 per cent respectively and to ampicillin, tetracycline and nalidixic acid in 93.3,60, 41.3, 34.4, 28.2, and 1.3 per cent respectively. fort ...19892687166
the sodium cycle: a novel type of bacterial energetics.the progress of bioenergetic studies on the role of na+ in bacteria is reviewed. experiments performed over the past decade on several bacterial species of quite different taxonomic positions show that na+ can, under certain conditions, substitute for h+ as the coupling ion. various primary na+ pumps (delta mu na+ generators) are described, i.e., na+ -motive decarboxylases, nadh-quinone reductase, terminal oxidase, and atpase. the delta mu na+ formed is shown to be consumed by na+ driven atp-syn ...19892687258
bacterial alginases. 19892688548
[evaluation of the causative bacteria of pneumonia in the elderly in recent years].a study of 62 cases of elderly pneumonia (ep) in their sixties and eighties with etiologic bacteria confirmed by cultures of sputum, blood or pleural effusion was carried out greater change of etiologic bacteria of ep in patients of eighties has been found when they were compared with those of sixties. in the group of eighties the incidence of gram-negative bacilli increased (77%), including pseudomonas aeruginosa (48.39%), klebsiella pneumoniae (17.35%) and enteric coli (9.68%), while staphyloc ...19892689107
extended broad spectrum beta-lactamase in klebsiella pneumoniae including resistance to cephamycins.a plasmid-encoded beta-lactamase conferring extended broad spectrum resistance including cephamycins was identified in a klebsiella pneumoniae strain isolated from a patient's wound. strains harbouring the plasmid pmvp-1 were resistant to penicillins, cephalosporins of all generations (parenteral and new oral compounds) cephamycins, aztreonam, tetracycline, chloramphenicol, sulfonamides and to all aminoglycosides modified by aac-(6)-i-transferase. beta-lactams still active against these strains ...19892689349
treatment of childhood bacterial meningitis.one hundred and eighty-seven children with identified bacterial meningitis were treated with intravenous cefotaxime: 15 patients were neonates, 79 infants, and 93 were aged from 1 to 14 years. causative organisms were: neisseria meningitidis in 80 cases, streptococcus pneumoniae in 41, haemophilus influenzae in 40, enteric gram-negative bacilli in 20 and staphylococcus spp. in six. enteric gram-negative bacilli included: salmonella spp. in 14 cases, klebsiella pneumoniae in two, and escherichia ...19892689353
epidemiology of extended spectrum beta-lactamases.beta-lactamases play a major part in resistance, as recently redemonstrated by the emergence of extended spectrum beta-lactamases. since its discovery in fr germany, shv-2 has been reported from four continents and ctx-1 (tem-3) was established in at least 26 french hospitals. more than 12 other enzymes have been individualized. the newest aspect of resistance was probably underestimated because most strains of enterobacteria (mainly klebsiella pneumoniae) appeared susceptible to oxyimino-beta-l ...19892689354
capsular types of klebsiella associated with bovine mastitis in japan. 19892689745
a comparative evaluation of oral ofloxacin versus intravenous cefotaxime therapy for serious skin and skin structure infections.in a single-blind, placebo-controlled randomized trial, 100 successive patients were enrolled with serious skin and soft-tissue infections, whose illnesses had precipitated an initial hospital admission or an extension of inpatient care. there were 93 evaluable patients who received either ofloxacin, 400 mg orally every 12 hours plus an intravenously administered placebo every eight hours, or cefotaxime, 2.0 g intravenously every eight hours plus an orally administered placebo every 12 hours. th ...19892690621
an improved broth-microdilution procedure for testing metal ion resistance of klebsiella pneumoniae.a new broth-microdilution method for testing metal ion resistance was designed in order to circumvent the formation of insoluble complexes between cations and compounds of the test medium. high-level cefotaxime resistant k. pneumoniae isolates tested by this procedure proved to be susceptible to cd, hg and zn but resistant to pb, mo and w. the metal ion resistance was not linked to the beta-lactam resistance gene.19892690846
evidence for a chromosomally determined bacteriocin production by klebsiella pneumoniae.location of the genes responsible for pneumocin production in klebsiella pneumoniae was examined by classical procedures. conjugal intrageneric transfers, elimination experiments with various curing agents, high temperature and plasmid isolation procedures showed that this strain did not harbour any plasmid. hence chromosomal location of the genetic determinants is suggested.19892691362
activity of amoxycillin/clavulanate against beta-lactamase-producing escherichia coli and klebsiella spp.we studied the susceptibility to the amoxycillin/clavulanate combination (2:1), and the characteristics of the beta-lactamases, of 1410 amoxycillin-resistant strains of enterobacteriaceae (785 of escherichia coli and 625 of klebsiella spp.). of the e. coli strains, 97.07% were susceptible to the combination and 98.85% produced plasmid-mediated beta-lactamases. of the klebsiella spp. strains, 87.84% were susceptible to the combination and 75.36% produced plasmid-mediated beta-lactamases. in both ...19892691485
[klebsiella pneumoniae meningitis associated with liver abscess: a case report].we report a rare case of klebsiella pneumoniae meningitis associated with liver abscess, which was successfully treated with cefotaxime (ctx), one of the third-generation cephalosporins. a 53-year-old man was admitted to keio university hospital on june 13, 1988, because of a fever and a headache. on june 3, he suddenly started shivering and his temperature rose to 39 degrees c. he then began to complain of polydipsia, polyuria, and a weight loss of 4 kg a week. on june 11, he developed a severe ...19892691713
[comparative studies on activities of antimicrobial agents against causative organisms isolated from urinary tract infections (1986). i. susceptibility distribution].susceptibilities to various antibacterial and antibiotic agents of bacterial strains isolated from urinary tract infections at 8 hospitals in japan from july to october in 1986 are summarized as follows. 1. enterococcus faecalis was susceptible to sulfamethoxazole/trimethoprim (st) and imipenem (ipm) with mic90s of 0.78 and 1.56 microgram/ml. minocycline had the strongest activity against staphylococcus aureus; the mics for all strains tested were lower than 0.39 microgram/ml. the mic80s of dicl ...19892691714
a novel, non-invasive promoter probe vector: cloning of the osmoregulated prou promoter of escherichia coli k12.we have constructed a novel promoter probe plasmid psb40, containing a unique lac-alpha-tetracycline marker gene tandem, which allows for both positive and negative selection of active promoters. promoters cloned in psb40 can be readily mobilized as ecori cassettes. using this vector we have performed a non-invasive analysis of the e. coli chromosome for promoters regulated by osmotic upshift. only one such promoter, subsequently identified as part of the prou operon, was isolated. a sequence of ...19892691837
[a fosfomycin-gentamicin combination in the treatment of experimental endocarditis caused by klebsiella pneumoniae producing type tem-3 beta-lactamase].the authors studied the activity of fosfomycin (fos) and/or gentamicin (gen) against a klebsiella pneumoniae strain resistant to all beta-lactams--except cephamycins and imipenem--by production of a plasmid mediated extended broad-spectrum beta-lactamase-tem-3, to all aminoglycosides--except gentamicin--by production of a plasmid mediated 6' aminoglycoside acetyltransferase iv, to sulfonamides and to tetracyclines. in vitro, the combination fos (mic = mbc = 32 mg/l) + gen (mic = mbc = 2) appeare ...19892691965
infectious arthritis caused by klebsiella. a report of two cases.klebsiella arthritis is uncommon. this report describes 2 cases seen in one year in one hospital and reviews the previous 9 well-documented cases. despite a long delay in diagnosis, antibiotic treatment without drainage procedures resulted in complete cure in one patient and cure with some impairment in the other.19892692949
biochemical, immunological and physicochemical comparisons between ohio-1 and four shv-type beta-lactamases.the biochemical, immunological and physicochemical properties of the beta-lactamase ohio-1 were compared to those of four beta-lactamases commonly found in klebsiella pneumoniae: shv-1, shv-3 and the beta-lactamases of strains gn 11-03 and gn 422. the substrate profile of shv-1, ohio-1 and of the beta-lactamases gn 11-03 and gn 422 were similar, while that of shv-3 appeared comparable to that of the extended spectrum shv-2. moreover, anti-tem-1 serum inactivated ohio-1 as well as shv-1 and the b ...19892693199
klebsiella pneumoniae haemolysin adsorption to red blood cells.it was necessary to incubate the klebsiella pneumoniae haemolysin with erythrocytes at 37 degrees c to produce the whole lytic action. the amount of attached klebolysin at 4 degrees c increased as its concentration in the medium increased, until the erythrocyte surface was saturated. treatment with 2-mercaptoethanol was necessary to permit the adsorption; it was inhibited by low concentrations of cholesterol. klebsolysin was immunogenic and its antiserum neutralized its own haemolytic effect and ...19892693425
comparative study of five plasmid-mediated ceftazidimases isolated in klebsiella pneumoniae.five plasmid-mediated beta-lactamases conferring a high level of resistance to ceftazidime were isolated from klebsiella pneumoniae strains. these ceftazidimases (caz) differed in their isoelectric point (from 5.3 to 8.2) and were encoded by large self-transferable plasmids of 85 kb (caz-2, caz-3) or greater than or equal to 150 kb (caz-1, caz-4, caz-5). the 85 kb plasmids seemed closely related to pcff04 encoding ctx-1 enzyme and belonged to the same incompatibility group 7 or m. these beta-lac ...19892693430
myopericardial involvement in klebsiella pneumonia infection. 19892693443
a new regulatory locus of the maltose regulon in klebsiella pneumoniae strain k21 identified by the study of pullulanase secretion mutants.this study has shown that klebsiella pneumoniae strain k21 differs from the previously characterized and closely related k. pneumoniae strain pap996 in that expression of the pullulanase gene (pula) and other genes of the maltose regulon is partially independent of exogenous inducer (maltose/maltotriose). mutants of strain k21 which are defective in pullulanase synthesis and/or secretion were isolated following tn10 mutagenesis. three phenotypic classes of mutants were identified. class i mutant ...19892693596
regulation of gene expression and cellular localization of cloned klebsiella aerogenes (k. pneumoniae) urease.the genes for klebsiella aerogenes (k. pneumoniae) urease were cloned and the protein was overexpressed (up to 18% of total protein consisted of this enzyme) in several hosts. the small size of the dna encoding urease (3.5 kb), the restriction map, and the regulation of enzyme expression directed by the recombinant plasmid are distinct from other cloned ureases. nickel concentration did not affect urease gene expression, as demonstrated by the high levels of apoenzyme measured in cells grown in ...19892693604
[respiratory infectious complications in patients with lung cancer].since respiratory infectious complications in lung cancer cases are major obstacles for adequate or intensive anticancer chemotherapy, they often affect prognosis unfavorably. such respiratory infections secondary to lung cancer generally occur on the basis of defects of the defence mechanism against infections due to disturbance in the clearance system in sites peripheral to bronchial obstruction or stenosis. the lowered concentration of antimicrobial agents at the site of infection, resulting ...19892693782
positive control of colanic acid synthesis in escherichia coli by rmpa and rmpb, two virulence-plasmid genes of klebsiella pneumoniae.in klebsiella pneumoniae, the mucoid phenotype, which is a virulence factor, is distinct from capsule production. it is positively controlled by a plasmid gene, designated rmpa. when introduced into certain escherichia coli strains, rmpa induces expression of a mucoid phenotype, which results from overproduction of colanic acid at 30 degrees c but not at 37 degrees c. in e. coli, production of colanic acid is regulated by three genes: rcsa and rcsb which act as positive regulators, and rcsc whic ...19892693894
analysis of the nag regulon from escherichia coli k12 and klebsiella pneumoniae and of its regulation.four genes, nagr, a, b and e, clustered in the nag locus of escherichia coli k12 and klebsiella pneumoniae, were cloned and physically mapped, and the corresponding gene products involved in amino sugar metabolism identified. expression of the nag genes was also analysed using a series of lacz fusions. in both bacteria, the genes are arranged in two divergent operons and controlled by a common nagr repressor. the corresponding gene nagr was found to map in the first operon together with the prom ...19892693951
molecular characterization of the gene encoding shv-3 beta-lactamase responsible for transferable cefotaxime resistance in clinical isolates of klebsiella pneumoniae.in klebsiella pneumoniae 86-4, cefotaxime resistance was due to a transferable broad-spectrum beta-lactamase, shv-3. the plasmid-borne gene encoding shv-3 has been cloned, and the primary structure of the enzyme was deduced from its nucleotide sequence. shv-3 differs from shv-1 in two positions. the extended substrate profile of shv-3 probably results from the substitution of ser-213 for gly, as in shv-2, whereas replacement of arg-180 by leu resulted in a decrease in the pi from 7.6 to 7.0. the ...19892694951
a transient-kinetic study of the nitrogenase of klebsiella pneumoniae by stopped-flow calorimetry. comparison with the myosin atpase.the pre-steady-state kinetics of mgatp hydrolysis by nitrogenase from klebsiella pneumoniae were studied by stopped-flow calorimetry at 6 degrees c and at ph 7.0. an endothermic reaction (delta hobs. = +36 kj.mol of atp-1; kobs. = 9.4 s-1) in which 0.5 proton.mol of atp-1 was released, has been assigned to the on-enzyme cleavage of mgatp to yield bound mgadp + pi. the assignment is based on the similarity of these parameters to those of the corresponding reaction that occurs with rabbit muscle m ...19892695063
cloning and sequence analysis of the ntra (rpon) gene of pseudomonas putida.the gene encoding a sigma factor ntra (rpon) was cloned from pseudomonas putida by cross-hybridization with a probe containing a part of the corresponding escherichia coli gene. the cloned gene complemented an ntra mutation of e. coli in activation of xyl genes on the tol plasmid. the predicted amino acid (aa) sequence of p. putida ntra (497 aa; mr 56,215) is highly homologous to ntra proteins from azotobacter vinelandii (81.7%), klebsiella pneumoniae (52.6%), and rhizobium meliloti (36.1%). the ...19892695395
incidence of klebocinogeny using two indicator systems.the incidence of bacteriocinogeny among 117 clinical isolates of klebsiella pneumoniae was examined using two systems of indicators-k. pneumoniae wc indicator and the abbott-shannon set of indicators. none of the isolate tested produced bacteriocin active on k. pneumoniae wc while 23 per cent positivity was observed with the abbott-shannon indicators. most of the bacteriocin producers were urinary isolates (53.8%) followed by 15.3 and 30.7 per cent respectively of faecal and miscellaneous isolat ...19892695458
klebsiella pneumonia with lung abscess. 19892695517
identification of dna regions homologous to nitrogen fixation genes nife, nifus and fixabc in azospirillum brasilense sp7.a 30 kb dna region from azospirillum brasilense sp7, containing the nitrogenase structural genes (nifhdk), has been cloned. the presence of nif genes, in the 20 kb located next to nifhdk, was explored by tn5 mutagenesis after subcloning various restriction fragments in the broad-host-range suicide vehicle psup202. over 25 mutations due to tn5 random insertions were obtained in the 20 kb and each recombined into the genome of strain sp7. four new nif loci were identified, located at about 4, 9, 1 ...19892695597
[susceptibility of bacteria isolated from patients with lower respiratory tract infections to antibiotics (1986)].enlisting the help of various research institutions across the nation, ikemoto et al. have been pooling cultures of clinical isolates of respiratory tract infections and mapping out the correlations between patient backgrounds and the causative bacteria and the changes in the sensitivity spectra of the bacteria to various antibacterial and antibiotic agents annually since 1981. the following is a report of the 1986 findings. during the period from september, 1986 to march, 1987, 558 cases of res ...19892695657
mutations in genes downstream of the rpon gene (encoding sigma 54) of klebsiella pneumoniae affect expression from sigma 54-dependent promoters.two open reading frames (orfs), designated orf95 and orf162, downstream of the klebsiella pneumoniae sigma 54 structural gene (rpon) have been sequenced and shown to encode polypeptides of 12 kd and 16 kd, respectively. orfs homologous to orf95 are present downstream of four out of five rpon genes sequenced to date from a range of gram-negative bacteria, and orf162 is also conserved, at least in pseudomonas putida. chromosomal mutations have been created in each gene using a kan cassette and bot ...19892695747
[the compositional characteristics of the cellular fatty acids in strains of klebsiella pneumoniae serovar k 1].klebsiella pneumoniae, serovar k1 strains, differ essentially in the composition of cellular fatty acids from serovar strains k 2, k 3, k 7-k 72, k 74-k 80 of this species and are analogous to k. rhinoscleromatis and k. ozaenae by the given trait. the differences concern the concentration of cyclopropane fatty acids and their biosynthetic precursors--monounsaturated fatty acids, that is typical of a number of other bacteria belonging to the related species and, evidently, may be a marker of phen ...19892695794
[urinary tract infection in the newborn infant].twenty-eight cases of urinary tract infection in newborns with positive urinoculture and suggestive clinical symptomatology are reviewed. the incidence was 0.24%, being most frequent in preterm and postterm newborns. male neonates was more affected. failure to thrive, excessive weight loss, poor feeding, diarrhoea, vomiting and jaundice are the most relevant clinical signs. e. coli and klebsiella are the most frequent organism isolated, followed by enterobacter and candida. the presence of metab ...19892696389
aminoglycoside resistance patterns in clinical isolates of e. coli and klebsiella sp. from czechoslovakia and the united states.resistance of gram-negative bacilli to aminoglycoside antibiotics differs by region and country. previous studies have demonstrated predominance of the nucleotidyltransferase anl(2") as the mechanism of enzymatic resistance to gentamicin in the united states and many european countries (federal republic of germany, switzerland, greece, turkey) whereas the acetylating enzymes aac(6') and aac(3) were the principal causes of resistance to aminoglycosides in japan and chile. in the present compariso ...19892696761
asymptomatic bacteriuria in pregnant nigerian patients.one-thousand out of a total obstetric population of 3,548 patients seen between january and december, 1985, were screened for asymptomatic bacteriuria. during the first trimester, the observed incidence was 5.3 per cent while in the second and third trimesters it was 4.1 and 2.8 per cent, respectively. the overall pick-up rate was 4.0 per cent. the significance of this observation was discussed. escherichia coli was the predominant causative micro-organism, accounting for 45 per cent of cases. a ...19892697475
beta-lactamase stability and antibacterial activity of cefpirome alone and in combination with other antibiotics.the antibacterial activity of cefpirome (hr810), a new cephalosporin, was compared with that of other "third-generation" cephalosporins, as well as cefuroxime, piperacillin and gentamicin. cefpirome was the most active beta-lactam antibiotic against gram-negative bacteria. the mic90 for enterobacteriaceae was always less than 0.5 ml/l except for enterobacter species. the mic90 against pseudomonas species was 2 mg/l, which was equal to that of ceftazidime and gentamicin. cefpirome was also more a ...19892698794
role of antibodies against outer-membrane proteins in murine resistance to infection with encapsulated klebsiella pneumoniae.in the assessment of immunity to the encapsulated virulent strain of klebsiella pneumoniae and its avirulent mutant defective for capsular polysaccharide (cps), killed bacterial vaccine of both strains could protect mice equally against challenge with 100 x ld50 of encapsulated wild strain. antisera to each strain conferred the same level of protection on naive mice upon transfer; the protective anti-mutant serum was highly capable of opsonizing the encapsulated bacteria. in addition to the comm ...19892699330
causal bacteria of pyogenic liver abscess.this is a review of bacteriologic data on 175 patients with pyogenic liver abscesses seen over a period of 8 years at veterans general hospital, taipei, taiwan. positive cultures were obtained from liver aspirates in 151 of the 163 patients in which cultures were taken. one hundred and twenty patient specimens grew one isolate and 31 specimens grew two or more isolates. a total of 149 aerobic gram-negative rods, 25 aerobic cocci and 29 anaerobes were isolated. ninety of the 159 patients from who ...19892699489
bombay experience in intensive respiratory care over 6 years.the experience of the intensive respiratory care in 930 cases treated from 1983 for 4 years and in 404 cases over the next 2 years is reported. the background operational problems are stressed. those between age 10 and 50 years did significantly better (p less than 0.05). the survival over the first 4 years in ippr cases was 16.3% and in non ippr group 71.8%; over the next 2 years, the former group, survival was 32.4 and 36.3%. the survival in asthmatic patients was high (76%). in cases with org ...19892699498
escherichia coli molybdoenzymes can be activated by protein fa from several gram-negative bacteria.six gram-negative bacteria (klebsiella pneumoniae, erwinia chrysanthemi, proteus vulgaris, serratia marescens, salmonella typhimurium, and pseudomonas aeruginosa) were shown to contain an fa-type protein capable of activating aponitrate reductase, apotrimethylamine n-oxide reductase and apoformate dehydrogenase of escherichia coli. protein fa activity was highest in erwinia chrysanthemi and lowest in pseudomonas aeruginosa. all the species also contained the low-mr (less than or equal to 1500) h ...19892699894
the kinetics of caz-5, a novel shv-related plasmid-mediated beta-lactamase with enhanced hydrolytic activity against ceftazidime.the kinetic constants for "caz-5", a novel plasmid-mediated beta-lactamase with noticeable activity against third-generation cephalosporins and particularly ceftazidime have been determined. two closely-related plasmid-mediated beta-lactamases have also been studied: shv-2 and pit-2 (also known as shv-1). these enzymes were synthesized constitutively; they were highly sensitive to the action of the inhibitors clavulanic acid and sulbactam and they lacked activity against the cephamycins and imip ...19892700319
trends and perspectives in nitrogen fixation research. 19892700537
[side effects of cefoperazone (third-generation cephalosporin) in a child with acute lymphoblastic leukemia]. 19892701238
[bacterial etiological factors of diarrhea in the stool of infants hospitalized in january 1987].the results are presented of the second part of the studies conducted for monitoring of the variability of bacterial factors causing diarrhoea in the youngest children. the presently reported study comprised 42 babies aged from 7 days to 18 months treated in hospital in january 1987. the number of children with diarrhoea hospitalized in this period was relatively smaller than in january 1985, while the incidence of enteropathogenic bacteria in stools was very similar. they included mainly klebsi ...19892701337
[an episode of hospital infection due to klebsiella pneumoniae in a neonatal department].enterotoxin-producing klebsiella pneumoniae was implicated in the induction of intrahospital infections in new-born babies. a total of 46 children and 4 adults (hospital personnel) were involved. most of the subjects (82.6%) had median and light forms of gastroenterocolitis, and recovered following biological re-equilibration. in 17.39% of the cases the evolution was more severe due to advanced dehydration and secondary dissemination of the infection. two children (approximately 4%) died. factor ...19892701342
psychrotrophic, proteolytic and lipolytic properties of enterobacteriaceae isolated from milk and dairy products.most of the enterobacteriaceae strains (73 out of 75) isolated in a previous study (wessels et al., 1988) were psychrotrophic on agar plates, with the exception of enterobacter cloacae strains. the enterobacteriaceae strains were largely non-proteolytic on milk agar medium although limited numbers of e. cloacae, serratia rubidaea and klebsiella oxytoca strains were capable of proteolytic activity at 25 degrees c. the e. cloacae and k. oxytoca strains positive at 25 degrees c were also proteolyti ...19892701399
options for the treatment of serious infections with interleukin-1.in this paper, the effects of recombinant human interleukin-1 (il-1) on non-specific resistance to infection are reviewed. in experiments in neutropenic mice, a single injection of a low dose of il-1 (8-800 ng) appears to protect against death from lethal pseudomonas aeruginosa and candida albicans infections. in non-neutropenic mice protection can also be obtained with such dosages of il-1 in infection caused by klebsiella pneumoniae or listeria monocytogenes. low dosages of il-1 are also able ...19892701646
sink flora in a long-stay hospital is determined by the patients' oral and rectal flora.sinks in a new long-stay hospital (lsh) were cultured weekly during 4 consecutive months to evaluate the microbial profile before and after occupancy of the hospital. from the elderly patients admitted to the patient care rooms oral and rectal specimens were collected to examine the contribution of the patients' flora to the sink contamination. isolates were typed biochemically, serologically and by susceptibility pattern. before occupancy gram-negative bacilli were not isolated. once the elderl ...19892703019
oral treatment with ru 41.740 (biostim) in patients with advanced colorectal cancer: influence on the blood lymphocyte population.twelve patients with advanced colorectal carcinoma received oral treatment with ru 41.740, an immunomodulatory drug obtained from klebsiella pneumoniae. the patients received three courses of ru 41.740, each consisting of 8 mg daily for 7 consecutive days, with free intervals of 3 weeks. this treatment did not significantly change the distribution of various lymphocyte subsets in the blood or the nk activity of the lymphocytes. however, pha reactivity of purified lymphocytes increased significan ...19892707939
open reading frame 5 (orf5), encoding a ferredoxinlike protein, and nifq are cotranscribed with nife, nifn, nifx, and orf4 in rhodobacter capsulatus.dna sequence analysis of a 1,600-base-pair fragment located downstream of nifenx in nif region a of rhodobacter capsulatus revealed two additional open reading frames (orfs): orf5, encoding a ferredoxinlike protein, and nifq. the ferredoxinlike gene product contained two cysteine motifs, typical of ferredoxins coordinating two 4fe-4s clusters, but the distance between these two motifs was unusual for low-molecular-weight ferredoxins. the r. capsulatus nifq gene product shared a high degree of ho ...19892708314
the dna sequence of the rhodobacter capsulatus ntra, ntrb and ntrc gene analogues required for nitrogen fixation.we have determined the dna sequence for the genes nifr1, nifr2 and nifr4 in the photosynthetic bacterium rhodobacter capsulatus. these genes regulate transcription of the nifhdk operon and so limit the expression of nitrogen fixation activity to periods of low environmental concentrations of both oxygen and fixed nitrogen. the sequences of these three genes are similar to components of the ntr regulation system in escherichia coli and klebsiella pneumoniae. the two-component regulatory system of ...19892710108
bacteriological findings after premature rupture of the membranes.of 243 children born after premature rupture of the membranes (prom) 61 (26%) had the same bacteria in placental arterial blood, in ear swabs (taken deep from the external auditory canal) and in meconium. the predominant organisms were e. coli, bacteroides fragilis, streptococcus faecalis (enterococci) and streptococcus agalactiae (group b streptococci). the infection rate was only 10% if the membranes had ruptured within 24 h of the onset of labour and 30% if the interval was longer than 24 h. ...19892712599
epidemiological typing of enterobacter aerogenes.the applicability of enterobacter cloacae and klebsiella typing reagents for classifying clinical strains of enterobacter aerogenes was evaluated. of 75 strains, none were agglutinated by e. cloacae o antisera or were sensitive to e. cloacae bacteriophages. in contrast, 70 strains reacted with klebsiella capsular antisera. two-thirds of the strains were lysed by klebsiella typing phages. a set of five e. aerogenes bacteriocin producers classified 92% of strains into 15 sensitivity types. in conc ...19892715326
[stimulation of nonspecific immune defense and antibody synthesis with zymosan].a local sterile inflammation was induced in mice of different inbred strains by means of an i.p. injection of zymosan, a water-insoluble polysaccharide of the cell wall of saccharomyces cerevisiae. this resulted in a strong enhancement of the unspecific resistance against infections with a ld 90 of gram-negative bacteria (escherichia coli, pseudomonas aeruginosa, klebsiella pneumoniae and bordetella bronchiseptica). furthermore, the treatment with zymosan before or after an immunization with she ...19892718888
retention of bacterial lipopolysaccharide at the site of subcutaneous injection.the tissue distribution of klebsiella pneumoniae o3 lipopolysaccharide (ko3 lps) was studied in mice injected subcutaneously (s.c.) or intraperitoneally (i.p.) with 125i-labeled ko3 lps. marked retention of ko3 lps radioactivity could be found at the site of s.c. injection for several weeks. on the other hand, about 85% of the radioactivity rapidly disappeared from the peritoneal cavity within 6 h after i.p. injection. the long-term presence of ko3 lps at the injection site was also supported by ...19892722239
ludwig's angina: an analysis of 14 cases.ludwig's angina remains a potentially lethal disease entity as it causes rapidly progressive airway obstruction, although the current mortality rate is low. early surgical intervention should be carried out in severe cases which show signs of fluctuation, abscess formation or other serious complications. we report our experience with 14 cases of ludwig's angina, 12 of which (86%) were of dental origin. only one case was complicated with klebsiella pneumoniae septicemia which resolved upon treatm ...19892727632
[infection and immunosuppression in cancer patients].septicemia in hematologic malignancies and infection of herpes zoster in cancer patients were studied, and trend in organisms in a cancer hospital was investigated. 1) septicemia in hematologic malignancies. the success rate of antibiotic therapy for septicemia was 76% if the patients were not under antibiotic therapy when septicemia developed. but recovery from septicemia was only 25% if the patients were undergoing antibiotic therapy when septicemia developed. some 90% of neutropenic patients ...19892730015
aztreonam in the treatment of aerobic, gram-negative bacillary infections in pediatric patients.aztreonam was administered to 20 children diagnosed as having any of the following infections: urinary tract infection, pneumonia, meningitis, and abscess of the appendix. haemophilus influenzae, escherichia coli, and klebsiella pneumoniae were isolated. the minimum inhibitory concentrations of aztreonam for these bacteria ranged from 0.03 to 0.5 micrograms/ml. all patients were clinically and bacteriologically cured within 5-16 days of treatment. six months after completion of therapy, patients ...19892731447
aztreonam in the treatment of gram-negative meningitis and other gram-negative infections.ninety patients (41 males, 49 females) with a diagnosis of meningitis, urinary tract infection (uti), gastroenteritis or other miscellaneous gram-negative infections were enrolled. their ages ranged from 7 days to 10 years, with a mean age of 4 months. 58 (63%) patients had an etiology confirmed by either positive culture (52; 89%) or latex agglutination (6; 10%). 41 of these patients had meningitis diagnosed by positive cse culture (38) or by positive csf latex agglutination (3); 27/41 patients ...19892731448
in-vitro interactions of fce 22101 with aminoglycosides against gram-negative rods.agar dilution mics of fce 22101 were measured for 894 consecutively-isolated gram-negative rods from clinical specimens (413 escherichia coli, 104 klebsiella spp., 54 enterobacter spp., 19 citrobacter spp., 131 proteus spp., 43 acinetobacter spp., 9 serratia spp., 3 providencia spp., 4 yersinia spp., 3 hafnia spp. and 111 pseudomonas spp.). excluding pseudomonas spp., 98% of these isolates were susceptible to 8 mg/l fce 22101. resistance (mic greater than 8 mg/l) varied from 11% in serratia spp. ...19892732132
screening of isoquinoline alkaloids and their derivatives for antibacterial and antifungal activities.a screening test of antimicrobial activities for some of the isoquinoline alkaloids and their first and second hofmann elimination products was conducted in this study. results showed that (+)-actinodaphnine (1), (+)-n-me-actinodaphnine (2), (+)-anonaine (17), (-)-xylopine (19) and (-)-n-me-xylopine mei (20), had the strongest inhibitory activities against three g(+) bacteria (bacillus cereus, micrococcus sp. and staphylococcus aureus) mic greater than or equal to 50 micrograms/ml). whereas anhy ...19892733073
[a case of emphysematous pyelonephritis combined with xanthogranulomatous pyelonephritis].a case of emphysematous pyelonephritis, xanthogranulomatous pyelonephritis histologically, is reported. a 49-year-old female patient was referred to our department from the department of internal medicine because abdominal ultrasonography demonstrated left renal swelling with gas echo. computed tomographic scan showed much emphysema in the left kidney. although aggressive treatment with broad spectrum antibiotics and immunoglobulin had been performed, subfever and left lumbago continued. thereaf ...19892735241
intestinal perforation in children.there were 102 cases of intestinal perforation seen in children at the department of paediatric surgery at s.s. hospital, varanasi during a 3 year period. enteric (typhoid) perforation (29%), intussusception (15%) ascaris lumbricoides infestation (9%) and appendicitis (9%), which are rarities in the reported literature, were the major causes of intestinal perforation. radiological evidence of pneumoperitoneum was seen in 88% of patients. the majority of cases in this study were older than 5 year ...19892735889
enoxacin: in vitro efficacy and its future therapeutic role in the pakistani health-care system.because laboratory microbiological diagnosis is not readily available for 80% of the total population of pakistan (120 million people), clinicians in large rural areas have been compelled to use several antibiotics in any individual case of resistant and severe infection. this practice has resulted in an increasing number of resistant strains, particularly those of salmonella, pseudomonas, escherichia coli, klebsiella, enterobacter, staphylococcus, and shigella. also, multiple resistance to peni ...19892736569
comparative in vitro activity of ciprofloxacin and other unrelated antimicrobials against bacterial respiratory tract pathogens.ciprofloxacin is a new fluorinated 4-quinolone with a broad spectrum of antimicrobial activity which includes both gram-negative and gram-positive bacteria. in this study the in vitro activity of ciprofloxacin has been determined against bacteria associated with respiratory tract infections and compared with that of other antimicrobial agents used in the therapy of such infections. ciprofloxacin (mic90 0.008 mg/l) was highly active against haemophilus influenzae, including isolates producing bet ...19892737080
radiolabeled, nonspecific, polyclonal human immunoglobulin in the detection of focal inflammation by scintigraphy: comparison with gallium-67 citrate and technetium-99m-labeled albumin.the accumulation of nonspecific polyclonal human immunoglobulin (igg) radiolabeled with 125i or 111in was compared to that of [67ga]citrate and [99mtc]albumin in rats with deep thigh inflammation due to escherichia coli infection. serial scintigrams were acquired at 1, 3, 24, and in some cases, 48 hr after injection. as early as 3 hr postinjection, [111in]igg showed greater accumulation at the lesion than [99mtc]hsa (p less than 0.01). both [125i]igg and [111in]igg showed greater accumulation th ...19892738667
observations on sudanese camel nasal myiasis caused by the larvae of cephalopina titillator.forty-four camels slaughtered at nyala abattoir, western sudan, were examined for infection with the larvae of cephalopina titillator. the infection rate was found to be 100 p. 100. the parasitic burden ranged between 8-243 per animal. they were recovered throughout the year. the first stage larvae were noticed from december to may, indicating the breeding season of the fly. the larvae were found to cause visible pathological lesions on the nasopharynx. these were also demonstrated histopatholog ...19892740563
[the etiology of suppurative-inflammatory diseases caused by opportunistic microorganisms at the noninfectious disease clinic].5,853 strains of opportunistic microorganisms have been isolated from hospitalized patients at a polyclinic. the following microorganisms have been found to cause purulent inflammatory diseases most frequently: escherichia coli (21.6%), staphylococcus epidermidis (15.93%), staphylococcus aureus (14.54%), microorganisms of the genus klebsiella (11.86%), pseudomonas aeruginosa (7.91%) and microorganisms of the genus proteus (7.5%). in cases of mixed infections gram-negative bacteria prevail. the a ...19892741604
[materno-fetal infections caused by unusual germs. apropos of 9 cases].a retrospective study carried out from january 1981 through august 1988 identified nine cases of materno-fetal infections (staphylococcus aureus, 1 case; klebsiella pneumoniae, 3 cases; enterococcus, 3 cases; hemophilus influenzae, 1 case; and pneumococcus, 1 case) in six girls and three boys; four premature infants developed respiratory distress requiring mechanical ventilation. in four cases, maternal history found risk factors for infection. all patients developed circulatory failure and one ...19892742314
[bacterial septicemias in children with homozygous sickle cell anemia. analysis of 69 cases].a retrospective analysis of 69 case-reports of children with homozygous sickle cell anemia hospitalized from 1964 through 1985 at the kinshasa university pediatric hospital highlights these patient's high susceptibility to bacterial septicemia. among causative organisms, the most prevalent were salmonellae (20 cases), pneumococci (15 cases), and klebsiella (12 cases). clinical features of bacterial septicemia are identical in children with and without sickle cell anemia. bone and/or joint infect ...19892742315
rufloxacin (mf-934): in vitro and in vivo antibacterial activity.rufloxacin (mf-934) is a new quinolone which shows in vitro antibacterial activity against e. coli, salmonella, klebsiella, proteus and staphylococcus spp. lower in vitro activity was observed with pseudomonas, serratia, enterobacter and the streptococci group d. the antimicrobial activity of mf-934 in vitro is higher than that of nalidixic acid but lower than that of ciprofloxacin, ofloxacin, pefloxacin or norfloxacin. the protective effects of mf-934 in systemic infections in mice are lower th ...19892743869
clinical evaluation of imipenem/cilastatin in the therapy of severe infections in high-risk patients.a clinical trial was carried out to evaluate the effectiveness of treatment with imipenem/cilastatin in life-threatening infections in high-risk patients. thirty hospitalized patients (22 men and 8 women), aged 28 to 78 years, with impaired host defences and severe infections were treated with imipenem/cilastatin at a dosage ranging between 1 and 3 g daily i.v. at 8 or 12 h intervals. the average length of therapy was 8.61 +/- 3.14 days. the isolated organisms were as follows: escherichia coli [ ...19892743870
monoclonal antibodies against flagellar antigen of salmonella typhi.two hybrid cell clones secreting monoclonal antibodies against flagellar antigen isolated from salmonella typhi, were produced and characterized. the antibodies bound specifically to the flagellar strain of s. typhi and did not show any reactivity with a flagellar s. typhi or with flagellar strains of s. dublin, s. paratyphi a, s. paratyphi b, s. typhimurium, e. coli, pseudomonas aeruginosa and klebsiella pneumoniae. the antibodies recognized a determinant present on a group of proteins migratin ...19892744788
the problem of bacterial resistance to antibiotics among strains isolated from hospital patients in lagos and ibadan, nigeria.bacterial infections are still an important cause of illness and death in developing countries, where the widespread and indiscriminate use of antibiotics has led to serious problems of resistance to the older, less expensive agents. the results of routine sensitivity testing of clinical isolates from patients in lagos and ibadan, nigeria show a high prevalence of strains resistant to penicillin, tetracycline, ampicillin, co-trimoxazole and chloramphenicol, with between 70% and 90% of strains of ...19892745266
time to positivity for detection of bacteremia in neonates.the blood culture results of all samples obtained from newborns at grady memorial hospital, atlanta, ga., during a 6-month period were analyzed to determine the time required for a blood culture to become positive, the time at which a culture could safely be considered negative, and the spectrum of isolated organisms. during the study period, 1,248 samples were submitted from all nurseries and processed by an automated detection instrument (bactec nr660). of the 1,248 samples, 98 (7.8%) were pos ...19892745679
[antimicrobial activity of cefteram comparison with other oral antibiotics].antimicrobacterial activities of cefteram (cftm) against clinical isolates collected in 1988 were compared with those of new beta-lactams. 1. antibacterial activities of cftm against streptococcus pneumoniae, streptococcus pyogenes, haemophilus influenzae, branhamella catarrhalis isolated from acute respiratory tract infections were 8- to 16-fold higher than those of cefaclor (ccl). 2. activities of cefixime (cfix) were superior to those of cftm against b. catarrhalis, escherichia coli, klebsiel ...19892746861
the rhizobium meliloti fdxn gene encoding a ferredoxin-like protein is necessary for nitrogen fixation and is cotranscribed with nifa and nifb.sequencing of the rhizobium meliloti dna region downstream of nifa revealed the existence of nifb, fdxn and orf3. the molecular weight of the fdxn protein (mr 6830) and the distribution of cysteine residues in its deduced amino acid sequence is typical for low molecular weight bacterial ferredoxins. interposon insertion and plasmid integration mutagenesis demonstrated that fdxn is essential for nitrogen fixation in r. meliloti, whereas the predicted translation product of orf3 (mr 8708) is not n ...19892747618
dna sequence and genetic analysis of the rhodobacter capsulatus nifenx gene region: homology between nifx and nifb suggests involvement of nifx in processing of the iron-molybdenum cofactor.rhodobacter capsulatus genes homologous to klebsiella pneumoniae nife, nifn and nifx were identified by dna sequence analysis of a 4282 bp fragment of nif region a. four open reading frames coding for a 51,188 (nife), a 49,459 (nifn), a 17,459 (nifx) and a 17,472 (orf4) dalton protein were detected. a typical nifa activated consensus promoter and two imperfect putative nifa binding sites were located in the 377 bp sequence in front of the nife coding region. comparison of the deduced amino acid ...19892747620
comparative in vitro susceptibilities of 504 bacteremic isolates to ticarcillin plus clavulanic acid and other antimicrobial agents.a total of 504 clinical bacteremic isolates were tested for susceptibility to ticarcillin-clavulanic acid and 12 other antibiotics. ticarcillin-clavulanic acid showed superior antibacterial activity compared to penicillin, mezlocillin, piperacillin, ticarcillin, gentamicin, and amikacin against bacteremic isolates of methicillin-susceptible staphylococcus aureus and staphylococcus epidermidis. however, ticarcillin-clavulanic acid's activity was inferior to that of vancomycin against methicillin- ...19892752713
levels of bacteria, fungi, and endotoxin in bulk and aerosolized corn silage.three samples of silage taken from the surface of a silo and from depths of 20 and 45 cm in the silo were studied for identification of the potential agents causing symptoms of organic dust toxic syndrome. the samples were examined by dilution plating before and after aerosolization in an acoustical dust generator. aerosol samples were collected by liquid impinger and filter cassettes. the samples were examined for total aerobic bacteria, anaerobic bacteria, gram-negative bacteria, lactobacilli, ...19892757375
prognostic index in prediction of mortality from infective endocarditis.out of 176 patients with infective endocarditis complicating rheumatic (120) and congenital heart disease (38), mortality occurred in 35 patients (19.9%). presence of leukocytosis, heart failure, major embolisation and isolation of certain organisms including staphylococci, beta-haemolytic streptococci, pseudomonas and klebsiella were ominous with higher mortality rates compared with those when they were absent (p less than 0.02). stepwise logistic multiple regression was then applied and the fo ...19892759756
microbiological survey of selected imported spices and associated fecal pellet specimens.a microbiological survey was performed on 4 selected imported spices: black peppercorns, white peppercorns, coriander, and fennel seed. aerobic plate count values ranged from 10(4) to 10(7) colony-forming units (cfu)/g for black and white peppercorns and from 10(3) to 10(5) cfu/g for coriander and fennel seed. combined results of the 3-tube most probable number procedure and the api 20e kit indicated the presence of escherichia coli in 4 test samples of black peppercorns, 1 test sample of white ...19892759995
effects of cadmium, copper, magnesium, and zinc on the decomposition of citrate by a klebsiella sp.the effects of cd2+, cu2+, mg2+, and zn2+ on the decomposition of citric acid by a klebsiella sp. were studied by monitoring the degradation of [14c]citrate. the carbon concentration used was 10 micrograms of c liter-1, and the media were designed to provide at least 95% of the citrate complexed to the metal studied. after 72 h of incubation, 80% of the uncomplexed citric acid and 76% of the magnesium citrate had been decomposed. a marked inhibition was observed when cd2+, cu2+, or zn2+ was boun ...19892764560
[urinary tract infection in children: clinical analysis and investigation].the urinary tract is a common site for bacterial infection in childhood. the most important aspect of urinary tract infection in childhood is that it can lead to severe and progressive renal disease. from march 1983 to march 1987, 63 cases of suspected urinary tract infection were collected in taichung vgh. among them only 24 cases reached our diagnostic criteria. eight cases were within 2 years old, which all are male. sixteen cases were beyond 2 years old, which the ratio of male to female is ...19892766067
the predicted protein product of a pathogenicity locus from pseudomonas syringae pv. phaseolicola is homologous to a highly conserved domain of several procaryotic regulatory proteins.a ca. 20-kilobase (kb) region (hrp) that controls the interaction of pseudomonas syringae pv. phaseolicola with its host (pathogenicity) and nonhost plants (hypersensitive reaction) was previously cloned and partially characterized. in this study we defined the limits and determined the nucleotide sequence of a hrp locus (hrps), located near the right end of the hrp cluster. the largest open reading frame (orf302) in hrps has a coding capacity for a 302-amino-acid polypeptide. the predicted amin ...19892768197
long-term colonization of spinal cord injury patients with klebsiella pneumoniae.the duration of colonization of the human perineum, bowel, and urethra with klebsiella pneumoniae was studied in 10 male patients with spinal cord injury while they were undergoing rehabilitation in the hospital. colonization defined as persistence of klebsiellae of the same serotype occurred on 13 occasions in five of the patients for up to 55 days. colonization was less marked with klebsiella than with pseudomonas spp. the presence of quadriplegia correlated with klebsiella colonization and al ...19892768448
t-mod pathway, a reduced sequence for identification of gram-negative urinary tract pathogens.in this paper, we describe a reduced sequence of identification that includes t-mod medium, a selective and differential isolation medium which allows accurate presumptive identification of the most common gram-negative bacteria encountered in urine samples. the present study, performed on bacteria isolated from 1,762 independent urine samples, has shown that a few selected tests (lysine and ornithine decarboxylase, urease and trehalose fermentation tests) improve the identification accuracy of ...19892768451
sequential hemofiltration in mof associated with paracetamol intoxication and gram-negative sepsis. 19892768650
[studies of lomefloxacin in biliary tract infections].lomefloxacin (ny-198), a new antimicrobial quinolone, was examined for its antimicrobial activities against clinical isolates and clinical efficacies to biliary tract infections. the following results were obtained. 1. the mics of ny-198 against escherichia coli (20 strains) and klebsiella pneumoniae (20 strains) were good and similar to those of ofloxacin (oflx) or norfloxacin (nflx). the mics of ny-198 against pseudomonas aeruginosa (20 strains) were inferior by 1 dilution factor to oflx or nf ...19892769934
[effects of sulbactam on the activity of cefoperazone against various clinical isolates].sulbactam/cefoperazone (sbt/cpz) have been used in clinical infusion at ratios of 1:1 and 1:2 in japan and u.s.a., respectively. after an administration of these drugs as a 1:1 parenteral formulation, the ratio of levels of cpz and sbt in blood was 1:1/4 to 1:1/5 for 1 to 2 hours, whereas the ratio of free, unbound drug levels was 1:1.4 to 1:1.5. in urine these drugs were excreted at a ratio between 1:1 and 1:4 during 6 hours after the infusion. antimicrobial interaction studies using various co ...19892769941
[circulation of intestinal infection in the families of patients with rheumatic diseases and the state of humoral immunity to enterobacterial antigens].elisa quantitation of antibodies to klebsiella pneumonia, proteus mirabilis, and yersinia enterocolitica was conducted in 75 ankylosing spondylitis (as), rheumatoid arthritis (ra), and systemic lupus erythematosus (sle) probands and in 262 of their first-degree relatives. the control group comprised 28 healthy donors. sixteen (64 per cent) as probands (12 with b27+) and 26 (30.2 per cent) their relatives (14 with b27+) were found to have high titres of antibodies to klebsiella pneumonia. in 18 ( ...19892773562
antimicrobial activity of julifloricine isolated from prosopis juliflora.antimicrobial activity of julifloricine, an alkaloid isolated from prosopis juliflora, was studied in vitro against 40 microorganisms which included 31 bacteria, two candida species, five dermatophytic fungi and two viruses. significant inhibitory effect was noted against gram positive bacteria. the minimal inhibitory concentration (mic) for staphylococcus aureus, s. epidermidis, s. citreus, streptococcus pyogenes and sarcina lutea was 1 microgram/ml and against s. faecalis, s. pneumoniae, s. la ...19892775330
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