| 7tm-cadherins: developmental roles and future challenges. | the 7tm-cadherins, celsr/flamingo/starry night, represent a unique subgroup of adhesion-gpcrs containing atypical cadherin repeats, capable of homophilic interaction, linked to the archetypal adhesion-gpcr seven-transmembrane domain. studies in drosophila provided a first glimpse of their functional properties, most notably in the regulation of planar cell polarity (pcp) and in the formation of neural architecture. many of the developmental functions identified in flies are conserved in vertebra ... | 2010 | 21618823 |
| [dynamic flamingo therapy]. | a long follow up study of one minute unipedal standing therapy 3 times in a day to prevent femoral neck osteoporosis that have started from 1993 was reported. the registration from july 1993 to march 2004 were 86 cases which measured the femoral neck bone mineral density (bmd) according to dual energy x-ray absorptiometry (dxa) (hologic qdr 1000 and 2000) in a follow-up period. average age at starting exercise was 67.9 years old. all cases were female who were registered in our university hospit ... | 2008 | 18974448 |
| planar cell polarity: a bridge too far? | the mechanisms of planar cell polarity are being revealed by genetic analysis. recent studies have provided new insights into interactions between three proteins involved in planar cell polarity: flamingo, frizzled and van gogh. | 2008 | 18957252 |
| single-leg-stance (flamingo) radiographs to assess pelvic instability: how much motion is normal? | chronic pelvic instability is a relatively uncommon cause of pelvic and low-back pain. patients present with feelings of instability and mechanical symptoms. static radiographs are often inadequate to detect abnormal relative motion between the hemipelves consistent with chronic pelvic instability; dynamic views of the pelvis are required. we assessed the amount of physiologic motion present at the pubic symphysis in normal adult men and nulliparous and multiparous women with alternating-single- ... | 2008 | 18829908 |
| regulation of the pericycle proteome in maize (zea mays l.) primary roots by rum1 which is required for lateral root initiation. | lateral roots are all roots that are initiated in the pericycle cell layer of other roots during postembryonic development. the maize (zea mays l.) mutant rum1 (rootless with undetectable meristems 1) does not initiate lateral roots in the primary root. in the present study, two-dimensional electrophoresis proteome profiles of three biological replicates of pericycle cells isolated from the differentiation zone of 2.5-day-old wild-type and rum1 primary roots were generated. this early developmen ... | 2010 | 19962783 |
| [musculoskeletal rehabilitation and bone. locomotion system disorder with aging and rehabilitation]. | muscle weakness and fall of ability for balance occur as becoming old. it is the worst results to fall down, and to break their bones. it is easy to have fracture elder people so that there is osteoporosis, and therefore they cannot walk, and become bedridden for a purpose to prevent that a senior citizen becomes a care state required by fall, we define "the state that fall of ability for balance and locomotive system result from aging and shut ourselves up, and a fall risk rose" as musculoskele ... | 2010 | 20354330 |
| application of sypro ruby- and flamingo-stained polyacrylamide gels to western blot analysis. | western blots are widely used for analysis of the expression levels of specific proteins. blotting is conducted after sodium dodecyl sulfate or native polyacrylamide gel electrophoresis without staining the gel. however, when it is necessary to analyze the gel, duplicate polyacrylamide gels (one of which is stained) usually must be prepared, leading to the consumption of precious sample. thus, we have developed a convenient and efficient western blot method using a stained gel. this simple modif ... | 2010 | 20301812 |
| muscle function and postural balance in lifelong trained male footballers compared with sedentary elderly men and youngsters. | the present study investigated whether elderly subjects exposed to lifelong football training have better rapid muscle force characteristics, body composition and postural stability in comparison with untrained elderly. ten elderly men exposed to lifelong football training (fte; 69.6 +/- 1.4 years) and eight age-matched untrained elderly men (ue; 70.5 +/- 1.0 years) were studied and 49 untrained young men (uy; 32.4 +/- 0.9 years) served as a reference group. fte showed an elevated rate of force ... | 2010 | 20210903 |
| echinoid regulates flamingo endocytosis to control ommatidial rotation in the drosophila eye. | planar cell polarity (pcp) refers to a second polarity axis orthogonal to the apicobasal axis in the plane of the epithelium. the molecular link between apicobasal polarity and pcp is largely unknown. during drosophila eye development, differentiated photoreceptors form clusters that rotate independently of the surrounding interommatidial cells (ics). here, we demonstrate that both echinoid (ed), an adherens junction-associated cell adhesion molecule, and flamingo (fmi), a pcp determinant, are e ... | 2010 | 20110316 |
| the age-dependent divergence of strength and coordinating parameters among men and women: the cross-sectional studies. | the objective of these studies was to determine the gender-dependent changes of coordination and fitness parameters in function of age by means of observational, cross-sectional study. we studied 180 male and 180 female participants by means of flamingo, kinesthetic differentiation, spatial orientation, reaction to signals, arm bend and chair stand tests. generalized linear model (glm) and the welch test and the appropriate t-tests were used to compare the differences between the studied age gro ... | 2010 | 20083315 |
| membrane protein location-dependent regulation by pi3k (iii) and rabenosyn-5 in drosophila wing cells. | the class iii phosphatidylinositol-3 kinase (pi3k (iii)) regulates intracellular vesicular transport at multiple steps through the production of phosphatidylinositol-3-phosphate (pi(3)p). while the localization of proteins at distinct membrane domains are likely regulated in different ways, the roles of pi3k (iii) and its effectors have not been extensively investigated in a polarized cell during tissue development. in this study, we examined in vivo functions of pi3k (iii) and its effector cand ... | 2009 | 19798413 |
| preferred neck-resting position predicts aggression in caribbean flamingos (phoenicopterus ruber). | when flamingos rest, they typically lay their heads along their backs. in order to achieve this positioning they curve their necks to either the right or left of their midline. previously we have shown both individual and flock-level laterality of preferred neck-resting direction, with most birds preferring to rest their necks to their right (anderson, williams, & o'brien, 2009). as laterality has been shown to play a role in social cohesion (e.g., rogers & workman, 1989) and aggression (e.g., v ... | 2010 | 19657953 |
| why do flamingos stand on one leg? | a series of observational studies of captive caribbean flamingos phoenicopterus ruber were conducted to determine why flamingos rest on one leg. while frequently asked by the general public, this basic question has remained unanswered by the scientific community. here we suggest that the latency of flamingos to initiate forward locomotion following resting on one leg is significantly longer than following resting on two, discounting the possibility that unipedal resting reduces muscle fatigue or ... | 2013 | 19637281 |
| the wnt5/planar cell polarity pathway regulates axonal development of the drosophila mushroom body neuron. | axonal development is a fundamental process for circuit formation in the nervous system and is dependent on many cellular events, including axon initiation, elongation, guidance, and branching. the molecular mechanisms underlying these events have been well studied, especially for axon guidance. in the presence of a guidance cue, the polarization of a growth cone precedes the turning response, which is one example of the diverse forms of cell polarity. planar cell polarity (pcp) is another examp ... | 2011 | 21451033 |
| preliminary findings of a 4-month tai chi intervention on tenderness, functional capacity, symptomatology, and quality of life in men with fibromyalgia. | the study aimed to determine the effects of a 4-month tai chi intervention on tenderness, functional capacity, symptomatology, and quality of life in men with fibromyalgia. the effect of a 3-month detraining period was also analyzed. six men with fibromyalgia (age 52.3 ± 9.3 years) followed a 4-month tai chi intervention. the outcome variables were tenderness, functional capacity (30-second chair stand, handgrip strength, chair sit and reach, back scratch, blind flamingo, 8 feet up and go, and 6 ... | 2011 | 21406488 |
| eurofit test battery in patients with schizophrenia or schizoaffective disorder: reliability and clinical correlates. | to investigate the reproducibility of the eurofit physical fitness test battery in patients with schizophrenia or schizoaffective disorder. secondary aims were to assess clinical and demographic characteristics that correlate with the performance on the eurofit and evaluation of the feasibility of the test. | 2012 | 21398095 |
| a quest for the mechanism regulating global planar cell polarity of tissues. | most epithelial cells, besides their ubiquitous apical-basal polarity, are polarized within the plane of the epithelium, which is called planar cell polarity (pcp). using drosophila as a model, meaningful progress has been made in the identification of key pcp factors and the dissection of their intracellular molecular interactions. the long-range, global aspects of coordinated polarization and the overlying regulatory mechanisms that create the initial polarity direction have, however, remained ... | 2009 | 19560358 |
| management of a cutaneous squamous cell carcinoma in an american flamingo (phoenicopterus ruber). | a 32-year-old female american flamingo (phoenicopterus ruber) was presented with a squamous cell carcinoma of the middle digit of the right foot. no clinical, hematologic, or radiologic evidence of metastasis was present. salvage amputation of the digit resulted in complete cure, whereas previous electrosurgery and radiation therapy were unsuccessful. three years later, another squamous cell carcinoma was diagnosed in the middle digit of the left foot. the digit was also amputated. seven months ... | 2009 | 19530406 |
| noncanonical wnt signaling in vertebrate development, stem cells, and diseases. | wnt signaling regulates many aspects of vertebrate development and adult stem cells. deregulation of wnt signaling causes development defect and cancer. the signaling is categorized in two pathways: canonical and noncanonical. both pathways are initiated by wnt ligands and frizzled receptors. canonical pathway leads to β-catenin:t-cell factor/lymphoid enhancer factor-mediated gene expression, which regulates proliferation and differentiation of cells. noncanonical wnt signaling is mediated by in ... | 2010 | 21181886 |
| treatment of abnormal single-leg stance (flamingo) radiographs. opinion: nonoperative treatment; opinion: operative fixation, anterior plating. | | 2011 | 21164302 |
| efficacy of biodanza for treating women with fibromyalgia. | the objective of this study was to determine the effects of a 3-month biodanza intervention in women with fibromyalgia (fm). | 2010 | 21058885 |
| relations among physical activity patterns, lifestyle activities, and fundamental movement skills for finnish students in grade 7. | to investigate the relations among leisure time physical activity and in sport clubs, lifestyle activities, and the locomotor, balance manipulative skills of grade 7 students participating in finnish physical education at a secondary school in central finland completed self-report questionnaires on their physical activity patterns at leisure time and during sport club participation, and time spent watching television and using the computer and other electronic media. locomotor skills were analyz ... | 2009 | 19425451 |
| the effect of recreational soccer training and running on postural balance in untrained men. | the aim of this study was to examine the effect of intense intermittent exercise performed as soccer training or interval running in comparison with continuous endurance running exercise on postural balance in young healthy untrained males. young sedentary men were randomized to soccer training (soc, n = 10), continuous running (run; n = 9), high-intensity interval running (int; n = 7) or no training (con; n = 9). postural balance was evaluated pre and post 12 weeks of training using a 30-s sing ... | 2011 | 20924596 |
| application of sypro ruby- and flamingo-stained polyacrylamide gels to western blot analysis. | western blot analysis has been a useful method for analysis of expression levels of specific proteins and is conducted after sodium dodecyl sulfate (sds) or native polyacrylamide gel electrophoresis without staining the gel. however, when it is necessary to analyze the gel, duplicate polyacrylamide gels usually must be prepared, one of which is stained, leading to the consumption of precious sample. thus, we developed a convenient and efficient western blotting method using a stained gel. this s ... | 2009 | 19332019 |
| isolation of bacteria from remote high altitude andean lakes able to grow in the presence of antibiotics. | high altitude andean lakes are placed in puna desert over 4400 above sea level. completely isolated, they are exposed to extreme environmental factors like high levels of salinity, uv radiation and heavy metals and low concentrations of phosphorus. nevertheless, they are the habitat of enormous populations of three flamingo species that migrate among these lakes. previous reports have determined that bacteria isolated from these environments present high levels of resistance to antibiotics. the ... | 2009 | 19149698 |
| the atypical cadherin flamingo is required for sensory axon advance beyond intermediate target cells. | the drosophila atypical cadherin flamingo plays key roles in a number of developmental processes. we have used the sensory nervous system of the drosophila embryo to shed light on the mechanism by which flamingo regulates axon growth. flamingo loss of function mutants display a highly penetrant sensory axon stall phenotype. the location of these axon stalls is stereotypic and corresponds to the position of intermediate target cells, with which sensory axons associate during normal development. t ... | 2009 | 19146847 |
| flamingo regulates epiboly and convergence/extension movements through cell cohesive and signalling functions during zebrafish gastrulation. | during vertebrate gastrulation, the body axis is established by coordinated and directional movements of cells that include epiboly, involution, and convergence and extension (c&e). recent work implicates a non-canonical wnt/planar cell polarity (pcp) pathway in the regulation of c&e. the drosophila atypical cadherin flamingo (fmi) and its vertebrate homologue celsr, a 7-pass transmembrane protein with extracellular cadherin repeats, regulate several biological processes, including c&e, cochlear ... | 2009 | 19091770 |
| deterioration of basic coordinative parameters defines life quality of elderly. | the objective of the studies was to analyze the level of deterioration of basic coordinative parameters and to derive the present correlation. 180 female participants with no neurological disorders and limb surgery were studied by means of flamingo, kinesthetic differentiation, spatial orientation and reaction to signals tests. t-test for un-paired data and pearson correlation analyses were performed. nonlinear gradual deterioration of studied parameters in function of age was observed. the corr ... | 2009 | 19013652 |
| the influence of multiple administration of a psychomotor test on performance and learning. | exercise scientists frequently use criterion measure tests to assess levels of motor performance and physical fitness or to evaluate the success of their intervention programs. during this process, the same motor test might be administered multiple times. the aim of the present study was to examine whether familiarization with a psychomotor test would influence performance and/or learning. one hundred thirty (n = 130) primary school students participated in the study. participants were randomly ... | 2008 | 18815569 |
| differential stability of flamingo protein complexes underlies the establishment of planar polarity. | the planar polarization of developing tissues is controlled by a conserved set of core planar polarity proteins. in the drosophila pupal wing, these proteins adopt distinct proximal and distal localizations in apicolateral junctions that act as subcellular polarity cues to control morphological events. the core polarity protein flamingo (fmi) localizes to both proximal and distal cell boundaries and is known to have asymmetric activity, but the molecular basis of this asymmetric activity is unkn ... | 2008 | 18804371 |
| plutonium isotopes in marine sediments and some biota from the sudanese coast of the red sea. | measurements of (239+240)pu and (238)pu were carried out on marine biota as well as on sediments from the fringing reefs area extending towards north and south (flamingo bay) of portsudan harbour. the analyses were performed using radiochemical separation and alpha spectrometry. the range of the activity concentrations in marine sediments, in mbq kg(-1) dry weight, was found to be from 5.10 to 82.00 for (239+240)pu and from 0.89 to 8.63 for (238)pu. corresponding activity concentrations of (239+ ... | 2008 | 18641000 |
| heavy metals in flamingos (phoenicopterus ruber) from italian wetlands: the problem of ingestion of lead shot. | waterbirds are exposed to many contaminants, including lead from ingestion of shot and fishing sinkers. lead poisoning had never been reported in flamingos wintering in italian wetlands. our investigation stems from a case of four flamingos found dead in tuscany in 2002 with numerous lead shot in their gizzards. we therefore considered other specimens found dead in different italian wetlands. many lead shot found in gizzards and lead tissue concentrations confirmed the hypothesis of lead poisoni ... | 2008 | 18359016 |
| the cadherin superfamily. | the cadherins are a major class of membrane proteins with prominent roles in cell adhesion, and the regulation of tissue organisation and morphogenesis. the c. elegans genome encodes 13 cadherins, including representatives of the major cadherin sub-types that are conserved between insects and vertebrates: the so-called classic, fat-like, flamingo and calsyntenin classes. the function of most of these in c. elegans is still unknown, or poorly understood, mainly because clear loss-of-function muta ... | 2005 | 18050421 |
| expression profile of the cadherin family in the developing drosophila brain. | the drosophila genome encodes 17 members of the cadherin family of adhesion molecules, which in vertebrates has been implicated in patterning the nervous system through cell and axon sorting. with only a few exceptions all cadherins show widespread expression in the larval brain. what expression patterns have in common is that 1) they are global, in the sense that all lineages of the central brain or optic lobe, or both, show expression; and 2) expression is stage-specific: some cadherins are ex ... | 2008 | 18041774 |
| mass spectral compatibility of four proteomics stains. | with the recent introduction of new fluorescence stains to the proteomics market, there is now more choice available. sypro ruby, lavapurple, flamingo, and krypton total protein stains were compared for ease of use, image quality, and compatibility with protein identification by peptide mass fingerprinting (pmf) (maldi-tof). all four stains produced good images but with slightly different staining patterns. sypro was found to inhibit identification of cysteine and tryptophan containing peptides, ... | 2007 | 17929854 |
| alkaline bohr effect of bird hemoglobins: the case of the flamingo. | the hemoglobin (hb) substitution his-->gln at position alpha89, very common in avian hbs, is considered to be responsible for the weak bohr effect of avian hbs. phoenicopterus ruber ruber is one of the few avian hbs that possesses his at alpha89, but it has not been functionally characterized yet. in the present study the hb system of the greater flamingo (p. ruber roseus), a bird that lives in mediterranean areas, has been investigated to obtain further insight into the role played by the alpha ... | 2007 | 17655497 |
| effect of stent size on complications and recurrent dysphagia in patients with esophageal or gastric cardia cancer. | stents are commonly used for the palliation of dysphagia from esophageal or gastric cardia cancer. a major drawback of stents is the occurrence of recurrent dysphagia. large-diameter stents were introduced for the prevention of migration but may be associated with more complications. | 2007 | 17383456 |
| assessing detection methods for gel-based proteomic analyses. | proteomic analyses using two-dimensional gel electrophoresis (2de) depend heavily upon the quality of protein stains for sensitive detection. indeed, detection rather than protein resolution is likely a current limiting factor in 2de. the recent development of fluorescent protein stains has dramatically improved the sensitivity of in-gel protein detection and has enabled more accurate protein quantification. here, we have evaluated the overall quality and relative cost of five commercially avail ... | 2007 | 17367184 |
| interannual variations in feeding frequencies and food quality of greater flamingo chicks (phoenicopterus roseus): evidence from plasma chemistry and effects on body condition. | greater flamingos in southern spain foraged in areas distant from a breeding site, spending 4-6 days in foraging areas between successive visits to the colony to feed their chicks. during four years, we took blood samples from chicks to ascertain whether there were interannual variations in several blood parameters, indicative of food quality and feeding frequencies. when the chicks were captured, 20-31% of them had their crops empty, indicating that not all chicks were fed daily. additional evi ... | 2007 | 17360212 |
| anterograde jelly belly and alk receptor tyrosine kinase signaling mediates retinal axon targeting in drosophila. | anaplastic lymphoma kinase (alk) has been proposed to regulate neuronal development based on its expression pattern in vertebrates and invertebrates; however, its function in vivo is unknown. we demonstrate that alk and its ligand jelly belly (jeb) play a central role as an anterograde signaling pathway mediating neuronal circuit assembly in the drosophila visual system. alk is expressed and required in target neurons in the optic lobe, whereas jeb is primarily generated by photoreceptor axons a ... | 2007 | 17350579 |
| the atypical cadherin flamingo regulates synaptogenesis and helps prevent axonal and synaptic degeneration in drosophila. | the formation of synaptic connections with target cells and maintenance of axons are highly regulated and crucial for neuronal function. the atypical cadherin and g-protein-coupled receptor flamingo and its orthologs in amphibians and mammals have been shown to regulate cell polarity, dendritic and axonal growth, and neural tube closure. however, the role of flamingo in synapse formation and function and in axonal health remains poorly understood. here we show that fmi mutations cause a signific ... | 2007 | 17321750 |
| individual differences in the preferred neck-resting position of caribbean flamingos (phoenicopterus ruber). | when resting, flamingos often lay their heads along their backs. while in this position they must curve their necks to either the right or left of their midline. observations of captive caribbean flamingos at the philadelphia zoo (philadelphia, pa, usa) were conducted in order to determine if individual birds would display consistent preferences in neck-resting position over multiple observations. while individual birds were shown to vary greatly in regards to the strength and direction of their ... | 2009 | 18629741 |
| a phylogenomic study of birds reveals their evolutionary history. | deep avian evolutionary relationships have been difficult to resolve as a result of a putative explosive radiation. our study examined approximately 32 kilobases of aligned nuclear dna sequences from 19 independent loci for 169 species, representing all major extant groups, and recovered a robust phylogeny from a genome-wide signal supported by multiple analytical methods. we documented well-supported, previously unrecognized interordinal relationships (such as a sister relationship between pass ... | 2008 | 18583609 |
| asymmetric homotypic interactions of the atypical cadherin flamingo mediate intercellular polarity signaling. | acquisition of planar cell polarity (pcp) in epithelia involves intercellular communication, during which cells align their polarity with that of their neighbors. the transmembrane proteins frizzled (fz) and van gogh (vang) are essential components of the intercellular communication mechanism, as loss of either strongly perturbs the polarity of neighboring cells. how fz and vang communicate polarity information between neighboring cells is poorly understood. the atypical cadherin, flamingo (fmi) ... | 2008 | 18555784 |
| flamingos? nowt like that round here. | | 2008 | 18463271 |
| the cadherin flamingo mediates level-dependent interactions that guide photoreceptor target choice in drosophila. | quantitative differences in cadherin activity have been proposed to play important roles in patterning connections between pre- and postsynaptic neurons. however, no examples of such a function have yet been described, and the mechanisms that would allow such differences to direct growth cones to specific synaptic targets are unknown. in the drosophila visual system, photoreceptors are genetically programmed to make a complex, stereotypic set of synaptic connections. here we show that the atypic ... | 2008 | 18400160 |
| of cartridges and columns: new roles for cadherins in visual system development. | in this issue of neuron, two papers provide new insights into roles for local cadherin-based interactions during axon targeting in the drosophila visual system. using high-resolution analyses, chen and clandinin identify nonautonomous roles for the atypical cadherin flamingo during photoreceptor targeting, while nern et al. demonstrate that local cell type-specific roles for n-cadherin control layer-specific targeting of lamina neurons. | 2008 | 18400154 |
| endoprosthesis implantation at the pharyngo-esophageal level: problems, limitations and challenges. | to present our experience with endoscopic placement of an esophageal endoprosthesis in 19 patients. | 2006 | 16610065 |
| twinstar, the drosophila homolog of cofilin/adf, is required for planar cell polarity patterning. | planar cell polarity (pcp) is a level of tissue organization in which cells adopt a uniform orientation within the plane of an epithelium. the process of tissue polarization is likely to be initiated by an extracellular gradient. thus, determining how cells decode and convert this graded information into subcellular asymmetries is key to determining how cells direct the reorganization of the cytoskeleton to produce uniformly oriented structures. twinstar (tsr), the drosophila homolog of cofilin/ ... | 2006 | 16571634 |
| potential dual molecular interaction of the drosophila 7-pass transmembrane cadherin flamingo in dendritic morphogenesis. | seven-pass transmembrane cadherins (7-tm cadherins) play pleiotropic roles in epithelial planar cell polarity, shaping dendritic arbors and in axonal outgrowth. in contrast to their role in planar polarity, how 7-tm cadherins control dendritic and axonal outgrowth at the molecular level is largely unknown. therefore, we performed extensive structure-function analysis of the drosophila 7-tm cadherin flamingo (fmi) and investigated the activities of individual mutant forms mostly in dendritogenesi ... | 2006 | 16507587 |
| long-range coordination of planar polarity in drosophila. | the mechanisms by which cells become polarised in the plane of an epithelium have been studied in drosophila for many years. work has focussed on two key questions: firstly, how individual cells adopt a defined polarity, and secondly how the polarity of each cell within a tissue is aligned with its neighbours. it has been established that asymmetric subcellular localisation of a number of polarity proteins is an essential mechanism underlying polarisation of single cells. the process by which th ... | 2005 | 16299762 |
| isoform-specific interaction of flamingo/starry night with excess bazooka affects planar cell polarity in the drosophila wing. | epithelia display two types of polarity, apical-basal and planar cell polarity (pcp), and both are crucial for morphogenesis and organogenesis. pcp signaling pathways comprise transmembrane proteins, such as flamingo/starry night, and cytoplasmic, membrane-associated proteins such as dishevelled. during establishment of pcp in the drosophila wing, pcp proteins accumulate apically in distinct "cortical domains" on proximal and distal plasma membranes. this finding suggests that their localized fu ... | 2007 | 17304516 |
| cadherins in development: cell adhesion, sorting, and tissue morphogenesis. | tissue morphogenesis during development is dependent on activities of the cadherin family of cell-cell adhesion proteins that includes classical cadherins, protocadherins, and atypical cadherins (fat, dachsous, and flamingo). the extracellular domain of cadherins contains characteristic repeats that regulate homophilic and heterophilic interactions during adhesion and cell sorting. although cadherins may have originated to facilitate mechanical cell-cell adhesion, they have evolved to function i ... | 2006 | 17158740 |
| low-frequency vibratory exercise reduces the risk of bone fracture more than walking: a randomized controlled trial. | whole-body vibration (wbv) is a new type of exercise that has been increasingly tested for the ability to prevent bone fractures and osteoporosis in frail people. there are two currently marketed vibrating plates: a) the whole plate oscillates up and down; b) reciprocating vertical displacements on the left and right side of a fulcrum, increasing the lateral accelerations. a few studies have shown recently the effectiveness of the up-and-down plate for increasing bone mineral density (bmd) and b ... | 2006 | 17137514 |
| the cadherin superfamily in neuronal connections and interactions. | neural development and the organization of complex neuronal circuits involve a number of processes that require cell-cell interaction. during these processes, axons choose specific partners for synapse formation and dendrites elaborate arborizations by interacting with other dendrites. the cadherin superfamily is a group of cell surface receptors that is comprised of more than 100 members. the molecular structures and diversity within this family suggest that these molecules regulate the contact ... | 2007 | 17133224 |
| two separate molecular systems, dachsous/fat and starry night/frizzled, act independently to confer planar cell polarity. | planar polarity is a fundamental property of epithelia in animals and plants. in drosophila it depends on at least two sets of genes: one set, the ds system, encodes the cadherins dachsous (ds) and fat (ft), as well as the golgi protein four-jointed. the other set, the stan system, encodes starry night (stan or flamingo) and frizzled. the prevailing view is that the ds system acts via the stan system to orient cells. however, using the drosophila abdomen, we find instead that the two systems ope ... | 2006 | 17075008 |
| differential activities of the core planar polarity proteins during drosophila wing patterning. | during planar polarity patterning of the drosophila wing, a "core" group of planar polarity genes has been identified which acts downstream of global polarity cues to locally coordinate cell polarity and specify trichome production at distal cell edges. these genes encode protein products that assemble into asymmetric apicolateral complexes that straddle the proximodistal junctional region between adjacent cells. we have carried out detailed genetic analysis experiments, analysing the requiremen ... | 2007 | 17045581 |
| cephalic vascular anatomy in flamingos (phoenicopterus ruber) based on novel vascular injection and computed tomographic imaging analyses. | head vascular anatomy of the greater (or caribbean) flamingo (phoenicopterus ruber) is investigated and illustrated through the use of a differential contrast, dual vascular injection technique, and high-resolution x-ray computed tomography (ct), allowing arteries and veins to be differentiated radiographically. vessels were digitally isolated with segmentation tools and reconstructed in 3d to facilitate topographical visualization of the cephalic vascular tree. major vessels of the temporal, or ... | 2006 | 16964609 |
| [physical fitness of short-statured boys as related to percentile norms for calendar or growth age]. | to assess the physical fitness of short-statured boys aged 7 - 20 years by applying fitness norms established for the polish population in relation to calendar or growth age. | 2006 | 16813718 |
| tracking of physical fitness and physical activity from youth to adulthood in females. | to evaluate stability of physical fitness and physical activity from adolescence into middle adulthood in flemish females. | 2006 | 16775554 |
| establishment and maintenance of planar epithelial cell polarity by asymmetric cadherin bridges: a computer model. | animal scales, hairs, feathers, and cilia are oriented due to cell polarization in the epithelial plane. genes involved have been identified, but the signal and mechanism remain unknown. in drosophila wing polarization, the action of a gradient of frizzled activity is widely assumed; and cell-cell signalling by cadherins such as flamingo surely plays a major role. we present a computer model where reading the frizzled gradient occurs through biased, feedback-reinforced formation of flamingo-base ... | 2006 | 16258926 |
| [comparison of 3 types of covered self-expanding metal stents for the palliation of malignant dysphagia: results from the prospective ludwigshafen esophageal cancer register]. | endoscopic stenting with self-expanding metal stents (sems) has proved to be an efficient palliative endoscopic therapy option in treating malignant dysphagia. different types of sems have been examined previously in small randomized clinical trials. | 2005 | 16220450 |
| body composition and physical fitness of undernourished south african rural primary school children. | the purpose of this study was to determine the relationships between the body composition characteristics, body mass index (bmi), sum of skinfolds (ssf), % body fat (%bf), fat-free mass (ffm) and waist-to-hip ratio (whr), and nine physical fitness items in undernourished rural primary school children in ellisras, south africa. | 2005 | 15915157 |
| combinatorial activity of flamingo proteins directs convergence and extension within the early zebrafish embryo via the planar cell polarity pathway. | the seven-transmembrane protocadherin, flamingo, functions in a number of processes during drosophila development, including planar cell polarity (pcp). to assess the role(s) of flamingo1/celsr1 (fmi1) during vertebrate embryogenesis we have exploited the zebrafish system, identifying two fmi1 orthologues (zfmi1a and zfmi1b) and employing morpholinos to induce mis-splicing of zebrafish fmi1 mrnas, to both imitate mutations identified in drosophila flamingo and generate novel aberrant flamingo pr ... | 2005 | 15882862 |
| planar polarity of hair cells in the chick inner ear is correlated with polarized distribution of c-flamingo-1 protein. | hair cells of the vertebrate inner ear are directional mechanosensors: they have a polarity, defined by a vector in the plane of the sensory epithelium. it has been suggested that this polarity might be controlled by genes homologous to those that control planar cell polarity (pcp) in drosophila, and vertebrate homologues of the drosophila pcp genes van gogh/strabismus and flamingo/starry night are indeed essential for normal hair cell pcp. the underlying molecular mechanism is unclear, however. ... | 2005 | 15830377 |
| spalt transcription factors are required for r3/r4 specification and establishment of planar cell polarity in the drosophila eye. | the establishment of planar cell polarity in the drosophila eye requires correct specification of the r3/r4 pair of photoreceptor cells. in response to a polarizing factor, frizzled signaling specifies r3 and induces delta, which activates notch in the neighboring cell, specifying it as r4. here, we show that the spalt zinc-finger transcription factors (spalt major and spalt-related) are part of the molecular mechanisms regulating r3/r4 specification and planar cell polarity establishment. in mo ... | 2004 | 15509769 |
| follow-up of participants in the trois-rivières growth and development study: examining their health-related fitness and risk factors as adults. | the purpose of the study was to examine the effect of daily physical education in primary school on some indices of fitness (pwc170/kg, handgrip strength, sit and reach flexibility, abdominal muscle endurance, and balance), cardiovascular health (lipid profile, waist-to-hip ratio), and anthropometry in the adult years. four subsamples of participants in the trois-rivières growth and development study were examined: experimental men (n = 32), experimental women (n = 36), control men (n = 30), and ... | 2000 | 11534017 |
| causes and treatment of recurrent dysphagia after self-expanding metal stent placement for palliation of esophageal carcinoma. | recurrent dysphagia frequently complicates the palliative treatment of esophageal cancer with self-expanding metal stents. strategies for repeat interventions and subsequent outcomes have not been adequately reported to date. | 2004 | 15452784 |
| cell interactions and planar polarity in the abdominal epidermis of drosophila. | the integument of the drosophila adult abdomen bears oriented hairs and bristles that indicate the planar polarity of the epidermal cells. we study four polarity genes, frizzled (fz), prickle (pk), van gogh/strabismus (vang/stbm) and starry night/flamingo (stan/fmi), and note what happens when these genes are either removed or overexpressed in clones of cells. the edges of the clones are interfaces between cells that carry different amounts of gene products, interfaces that can cause reversals o ... | 2004 | 15329345 |
| diego interacts with prickle and strabismus/van gogh to localize planar cell polarity complexes. | planar cell polarity (pcp) in the drosophila eye is established by the distinct fate specifications of photoreceptors r3 and r4, and is regulated by the frizzled (fz)/pcp signaling pathway. before the pcp proteins become asymmetrically localized to opposite poles of the cell in response to fz/pcp signaling, they are uniformly apically colocalized. little is known about how the apical localization is maintained. we provide evidence that the pcp protein diego (dgo) promotes the maintenance of apic ... | 2004 | 15306567 |
| breaking cellular symmetry along planar axes in drosophila and vertebrates. | in many organs, epithelial cells are polarized not only along the apicobasal axis, but also along a second axis within a plane. acquisition of the latter polarity, known as planar cell polarity (pcp) or tissue polarity, is crucial for specialized cellular functions. genetic programming of pcp has been most thoroughly studied in drosophila, which has allowed identification of a number of regulatory molecules that are evolutionally conserved. one group of the regulators is responsible for interpre ... | 2003 | 14688226 |
| dentritic growth: don't go says flamingo. | | 2000 | 11086974 |
| use of large-diameter metallic stents to seal traumatic nonmalignant perforations of the esophagus. | surgery for traumatic, non-malignant perforation of the esophagus in patients presenting more than 24 hours after its occurrence carries a high morbidity and mortality. covered metallic stents have been used to effectively seal perforations in individual patients with boerhaave's syndrome. | 2003 | 14528208 |
| egfr signaling regulates ommatidial rotation and cell motility in the drosophila eye via mapk/pnt signaling and the ras effector canoe/af6. | epidermal growth factor-receptor (egfr) signaling is evolutionarily conserved and controls a variety of different cellular processes. in drosophila these include proliferation, patterning, cell-fate determination, migration and survival. here we provide evidence for a new role of egfr signaling in controlling ommatidial rotation during planar cell polarity (pcp) establishment in the drosophila eye. although the signaling pathways involved in pcp establishment and photoreceptor cell-type specific ... | 2003 | 14507782 |
| actin filament-stabilizing protein tropomyosin regulates the size of dendritic fields. | dendritic arbors of different neuronal subtypes cover distinct spatial territories, known as dendritic fields, to receive specific inputs in a nervous system. how the size of dendritic fields is determined by cell-intrinsic factors during development remains primarily unknown. to address this issue, we used the drosophila embryonic peripheral nervous system. in each hemisegment, six dorsal cluster dendritic arborization (da) neurons elaborate stereotypic dendritic branching patterns underneath t ... | 2003 | 12867499 |
| tiling of the drosophila epidermis by multidendritic sensory neurons. | insect dendritic arborization (da) neurons provide an opportunity to examine how diverse dendrite morphologies and dendritic territories are established during development. we have examined the morphologies of drosophila da neurons by using the marcm (mosaic analysis with a repressible cell marker) system. we show that each of the 15 neurons per abdominal hemisegment spread dendrites to characteristic regions of the epidermis. we place these neurons into four distinct morphological classes disti ... | 2002 | 12050135 |
| the atypical cadherin flamingo links frizzled and notch signaling in planar polarity establishment in the drosophila eye. | planar cell polarity is established in the drosophila eye through distinct fate specification of photoreceptors r3 and r4 by a two-tiered mechanism employing fz and notch signaling: fz signaling specifies r3 and induces dl to activate notch in r4. we show that the atypical cadherin flamingo (fmi) plays critical, but distinct, roles in both r3 and r4. fmi is first enriched at equatorial cell borders of r3/r4, positively interacting with fz/dsh. subsequently, fmi is upregulated in r4 by notch and ... | 2002 | 12015972 |
| asymmetric localization of frizzled and the determination of notch-dependent cell fate in the drosophila eye. | during patterning of the drosophila eye, a critical step is the notch-mediated cell fate decision that determines the identities of the r3/r4 photoreceptor pair in each ommatidium. depending on the decision taken, the ommatidium adopts either the dorsal or ventral chiral form. this decision is directed by the activity of the planar polarity genes, and, in particular, higher activity of the receptor frizzled confers r3 fate. | 2002 | 12015117 |
| the ankyrin repeat protein diego mediates frizzled-dependent planar polarization. | during planar polarization of the drosophila wing epithelium, the homophilic adhesion molecule flamingo localizes to proximal/distal cell boundaries in response to frizzled signaling; perturbing frizzled signaling alters flamingo distribution, many cell diameters distant, by a mechanism that is not well understood. this work identifies a tissue polarity gene, diego, that comprises six ankyrin repeats and colocalizes with flamingo at proximal/distal boundaries. diego is specifically required for ... | 2001 | 11703927 |
| frizzled signaling and cell-cell interactions in planar polarity. | the function of the frizzled pathway is essential for the formation of the array of distally pointing hairs found on the drosophila wing. previous research found that regulating the subcellular location for hair initiation controlled hair polarity. recent work argues a graded frizzled-dependent signal results in the accumulation of the frizzled, dishevelled and flamingo proteins along the distal edge of the wing cells. this cortical mark leads to the local activation of downstream gene products ... | 2001 | 11544034 |
| pink flamingo gloves. | | 1993 | 10125771 |
| laparoscopic salpingectomy in a hybrid flamingo. | | 1992 | 1441148 |
| a randomised prospective comparison of the flamingo wallstent and ultraflex stent for palliation of dysphagia associated with lower third oesophageal carcinoma. | covered metallic oesophageal stents offer effective palliation of malignant oesophageal strictures. however, first generation devices were associated with a high rate of migration, particularly when used in the lower oesophagus. | 2003 | 12801944 |
| are metal stents effective for palliation of malignant dysphagia and fistulas? | one of the available treatments for unresectable oesophagogastric malignancies is the insertion of metal stents. | 2003 | 12801040 |
| strabismus is asymmetrically localised and binds to prickle and dishevelled during drosophila planar polarity patterning. | planar polarity decisions in the wing of drosophila involve the assembly of asymmetric protein complexes containing the conserved receptor frizzled. in this study, we analyse the role of the van gogh/strabismus gene in the formation of these complexes and cell polarisation. we find that the strabismus protein becomes asymmetrically localised to the proximal edge of cells. in the absence of strabismus activity, the planar polarity proteins dishevelled and prickle are mislocalised in the cell. we ... | 2003 | 12756182 |
| the protocadherin flamingo is required for axon target selection in the drosophila visual system. | photoreceptor neurons (r cells) in the drosophila visual system elaborate a precise map of visual space in the brain. the eye contains some 750 identical modules called ommatidia, each containing eight photoreceptor cells (r1-r8). cells r1-r6 synapse in the lamina; r7 and r8 extend through the lamina and terminate in the underlying medulla. in a screen for visual behavior mutants, we identified alleles of flamingo (fmi) that disrupt the precise maps elaborated by these neurons. these mutant r1-r ... | 2003 | 12754514 |
| flamingo regulates r8 axon-axon and axon-target interactions in the drosophila visual system. | photoreceptors (r cells) in the drosophila retina connect to targets in three distinct layers of the optic lobe of the brain: r1-r6 connect to the lamina, and r7 and r8 connect to distinct layers in the medulla. in each of these layers, r axon termini are arranged in evenly spaced topographic arrays. in a genetic screen for mutants with abnormal r cell connectivity, we recovered mutations in flamingo (fmi). fmi encodes a seven-transmembrane cadherin, previously shown to function in planar cell p ... | 2003 | 12747830 |
| strabismus requires flamingo and prickle function to regulate tissue polarity in the drosophila eye. | tissue polarity in drosophila is regulated by a number of genes that are thought to function in a complex, many of which interact genetically and/or physically, co-localize, and require other tissue polarity proteins for their localization. we report the enhancement of the strabismus tissue polarity phenotype by mutations in two other tissue polarity genes, flamingo and prickle. flamingo is autonomously required for the establishment of ommatidial polarity. its localization is dynamic throughout ... | 2003 | 12642492 |
| test-retest reliability of the eurofit test battery administered to university students. | the purpose of this study was to examine the test-retest reliability of the eurofit motor fitness tests performed by university students. a total of 98 undergraduate students who were enrolled in physical education departments in greece participated (29 men aged 19.5 +/- 2.7 hr. and 66 women aged 19.4 +/- 2.7 yr.). all eurofit motor fitness tests and anthropometric measurements were obtained twice with one week between the two measurements. intraclass correlation coefficient indicated satisfacto ... | 2002 | 12578274 |
| palliative treatment of inoperable malignant esophageal strictures with metal stents: one center's experience with four different stents. | our center's experience with ultraflex, flamingo, sr stent and flexstent for the palliation of malignant esophageal strictures is reported, and current pertinent literature is reviewed. | 2002 | 12204402 |
| genetic manipulation of single neurons in vivo reveals specific roles of flamingo in neuronal morphogenesis. | to study the roles of intracellular factors in neuronal morphogenesis, we used the mosaic analysis with a repressible cell marker (marcm) technique to visualize identifiable single multiple dendritic (md) neurons in living drosophila larvae. we found that individual neurons in the peripheral nervous system (pns) developed clear morphological polarity and diverse dendritic branching patterns in larval stages. each md neuron in the same dorsal cluster developed a unique dendritic field, suggesting ... | 2002 | 12074553 |
| efficacy of training program for ambulatory competence in elderly women. | the optimal prevention of osteoporotic fractures in the elderly consists of increasing the bone density and preventing falls. we report on the efficacy of training program to promote ambulatory competence in elderly women. twenty-five elderly women were enrolled in our training program, which is a three-month program consisting of dynamic balance training with galileo 900 (novotec, pforzheim, germany) once a week, combined with daily static balance (standing on one leg like a flamingo) and resis ... | 2004 | 15247512 |
| armadillo/beta-catenin-dependent wnt signalling is required for the polarisation of epidermal cells during dorsal closure in drosophila. | at the end of germband retraction, the dorsal epidermis of the drosophila embryo exhibits a discontinuity that is covered by the amnioserosa. the process of dorsal closure (dc) involves a coordinated set of cell-shape changes within the epidermis and the amnioserosa that result in epidermal continuity. polarisation of the dorsal-most epidermal (dme) cells in the plane of the epithelium is an important aspect of dc. the dme cells of embryos mutant for wingless or dishevelled exhibit polarisation ... | 2004 | 15226252 |
| planar polarity from flies to vertebrates. | planar cell polarity (pcp) has been demonstrated in the epithelium of organisms from flies to humans. recent research has revealed that the planar organization of cells requires a conserved set of genes, known as the pcp genes. tbe pcp proteins frizzled (fz) and dishevelled (dsh) function as key players in pcp signalling. although fz and dsh are also involved in wingless (wg)/wnt signalling, these proteins have independent functions in a non-canonical pathway dedicated to pcp. reorganization of ... | 2004 | 14730010 |
| osteitis pubis and instability of the pubic symphysis. when nonoperative measures fail. | seven rugby players with osteitis pubis and vertical instability at the pubic symphysis were treated operatively after nonoperative treatment had failed to improve their symptoms. the vertical instability was diagnosed based on flamingo view radiographs showing greater than 2 mm of vertical displacement. the players had undergone at least 13 months of nonoperative therapy before surgery was considered. operative treatment consisted of arthrodesis of the pubic symphysis by bone grafting supplemen ... | 2017 | 10843126 |
| a new design metal stent (flamingo stent) for palliation of malignant dysphagia: a prospective study. the rotterdam esophageal tumor study group. | metal stents are not superior to conventional endoprostheses with respect to the incidence of recurrent dysphagia because of tumor ingrowth with uncovered stents and migration with their covered counterparts. to overcome these limitations, a partially covered (inside-out covering) metal stent with a conical shape and a varying braiding angle of the mesh along its length, the flamingo stent, has been developed. | 2000 | 10650254 |
| genes regulating dendritic outgrowth, branching, and routing in drosophila. | signaling between neurons requires highly specialized subcellular structures, including dendrites and axons. dendrites exhibit diverse morphologies yet little is known about the mechanisms controlling dendrite formation in vivo. we have developed methods to visualize the stereotyped dendritic morphogenesis in living drosophila embryos. dendrite development is altered in prospero mutants and in transgenic embryos expressing a constitutively active form of the small gtpase cdc42. from a genetic sc ... | 1999 | 10521399 |
| mosquito (aedes taeniorhynchus) resistance to methoprene in an isolated habitat. | salt-marsh mosquitoes (aedes taeniorhynchus), collected on 2 barrier islands in lee county, florida, that had been treated from 1989 to 1994 with 150-day methoprene briquets, were bioassayed with technical s-methoprene in the laboratory. susceptibility of the indigenous captiva strain (median lethal concentration [lc50] estimate, 6.71 ppb) collected from captiva island was 14.9-fold lower than the naive flamingo strain (lc50 estimate, 0.45 ppb) from everglades national park. the lover's key stra ... | 1998 | 9673923 |
| an epizootic of lead poisoning in greater flamingos (phoenicopterus ruber roseus) in spain. | during november 1992 to march 1993, and november 1993 to february 1994, 106 greater flamingos (phoenicopterus ruber) were collected dead or moribund in the wetlands of el fondo and salinas de santa pola, eastern spain. birds still alive were emaciated and had a bile-stained diarrhea. on necropsy, they had liquid in the upper digestive tract and the walls of their gizzards were stained dark green. fifty-three (93%) of 57 gizzards examined contained lead shot (range one to 277 shot), and fifty-fiv ... | 1997 | 9027700 |
| temporal and spatial variation in dispersal in the greater flamingo (phoenicopterus ruber roseus). | we studied movements of individually marked greater flamingos (phoenicopterus ruber roseus) born in the camargue, southern france, between their two most important breeding colonies in the western mediterranean (camargue and fuente de piedra, spain) from 1986 to 1992. the two sites differ in the frequency with which they offer suitable conditions for breeding. flamingos have bred each year in the camargue since 1974, but in only 12 of the past 22 years at fuente de piedra. higher colony fidelity ... | 1996 | 28307306 |