| exploring the antibacterial and antifungal potential of jellyfish-associated marine fungi by cultivation-dependent approaches. | fungi isolated from marine invertebrates are of considerable importance as new promising sources of unique secondary metabolites with significant biomedical potential. however, the cultivable fungal community harbored in jellyfish was less investigated. in this work, we seek to recover symbiotic fungi from different tissues of jellyfish nemopilema nomurai. a total of seven morphotypes were isolated, which were assigned into four genera (aspergillus, cladosporium, purpureocillium, and tilletiopsi ... | 2015 | 26637162 |
| avertoxins a-d, prenyl asteltoxin derivatives from aspergillus versicolor y10, an endophytic fungus of huperzia serrata. | aspergillus versicolor y10 is an endophytic fungus isolated from huperzia serrata, which showed inhibitory activity against acetylcholinesterase. an investigation of the chemical constituents of y10 led to the isolation of four new prenylated asteltoxin derivatives, named avertoxins a-d (2-5), together with the known mycotoxin asteltoxin (1). in the present study, we report structure elucidation for 2-5 and the revised nmr assignments for asteltoxin and demonstrated that avertoxin b (3) is an ac ... | 2015 | 26618211 |
| effect of water activity and titania p25 photocatalyst on inactivation of pathogenic fungi--contribution to the protection of public health. | the aim of this study was to determine the antifungal activity of titanium dioxide activated by indoor light on czapek yeast agar (cya). | 2015 | 26615661 |
| detection of boron removal capacities of different microorganisms in wastewater and effective removal process. | in this study boron removal capacities of different microorganisms were tested. candida tropicalis, rhodotorula mucilaginosa, micrococcus luteus, bacillus thuringiensis, bacillus cereus, bacillus megaterium, bacillus pumilus, pseudomonas aeruginosa and aspergillus versicolor were examined for their boron bioaccumulation capacities in simulated municipal wastewater. a. versicolor and b. cereus were found as the most boron-tolerant microorganisms in the experiments. also boron bioaccumulation yiel ... | 2015 | 26540546 |
| versixanthones a-f, cytotoxic xanthone-chromanone dimers from the marine-derived fungus aspergillus versicolor hdn1009. | six unusual xanthone-chromanone dimers, versixanthones a-f (1-6), featuring different formal linkages of tetrahydroxanthone and 2,2-disubstituted chroman-4-one monomers, were isolated from a culture of the mangrove-derived fungus aspergillus versicolor hdn1009. the absolute configurations of 1-6, representing the central and axial chirality elements or preferred helicities, were established by a combination of x-ray diffraction analysis, chemical conversions, and tddft-ecd calculations. the inte ... | 2015 | 26506221 |
| efficient biotransformation of ginsenoside rb1 to rd by isolated aspergillus versicolor, excreting β-glucosidase in the spore production phase of solid culture. | ginsenosides are the major pharmacological components in ginseng. microorganisms from a ginseng field were isolated to identify transformation of ginsenosides. based on hplc and lc-ms analysis, strain lfj1403 showed strong activities to transform ginsenoside rb1 to rd as the sole product. phylogenetic analysis of 18s rdna indicated that lfj1403 belonged to aspergillus versicolor. through comparing four systems of transforming rb1 to rd, strain lfj1403 was found to secrete ginsenoside-converting ... | 2015 | 26373416 |
| microbiological consequences of indoor composting. | recycling of organic waste appeals to more and more people. the aim of this study was to evaluate the microbiological contamination around organic waste bins at three distances over a 12-month period. contamination near the customary trash of control households was evaluated at the beginning to ensure that there is no recruitment bias. air samples using the mas 100 impactor were carried out in 38 dwellings that do household waste composting and in 10 dwellings of controls. collection of particle ... | 2016 | 26299932 |
| erratum to: development and performance assessment of a qualitative sybr® green real-time pcr assay for the detection of aspergillus versicolor in indoor air. | | 2015 | 26293339 |
| development and performance assessment of a qualitative sybr® green real-time pcr assay for the detection of aspergillus versicolor in indoor air. | currently, contamination of indoor environment by fungi and molds is considered as a public health problem. the monitoring of indoor airborne fungal contamination is a common tool to help understanding the link between fungi in houses and respiratory problems. classical analytical monitoring methods, based on cultivation and microscopic identification, depend on the growth of the fungi. consequently, they are biased by difficulties to grow some species on certain culture media and under certain ... | 2015 | 26184975 |
| fungal dna in dust in swedish day care centres: associations with respiratory symptoms, fractional exhaled nitrogen oxide (feno) and c-reactive protein (crp) in serum among day care centre staff. | to study associations between fungal dna in day care centres, fractional exhaled nitric oxide (feno) and inflammatory markers in day care centre staff. | 2016 | 26183154 |
| indirect immunodetection of fungal fragments by field emission scanning electron microscopy. | submicronic fungal fragments have been observed in in vitro aerosolization experiments. the occurrence of these particles has therefore been suggested to contribute to respiratory health problems observed in mold-contaminated indoor environments. however, the role of submicronic fragments in exacerbating adverse health effects has remained unclear due to limitations associated with detection methods. in the present study, we report the development of an indirect immunodetection assay that utiliz ... | 2015 | 26092450 |
| maldi-tof mass spectrometry fingerprinting: a diagnostic tool to differentiate dematiaceous fungi stachybotrys chartarum and stachybotrys chlorohalonata. | stachybotrys chartarum and stachybotrys chlorohalonata are two closely related species. unambiguous identification of these two species is a challenging task if relying solely on morphological criteria and therefore smarter and less labor-intensive approaches are needed. here we show that even such closely related species of fungi as s. chartarum and s. chlorohalonata are unequivocally discriminated by their highly reproducible maldi-tof-ms fingerprints (matrix assisted laser desorption/ionizati ... | 2015 | 26036596 |
| identification and biological evaluation of secondary metabolites from the endolichenic fungus aspergillus versicolor. | a chemical investigation of the endolichenic fungus aspergillus versicolor (125a), which was found in the lichen lobaria quercizans, resulted in the isolation of four novel diphenyl ethers, named diorcinols f-h (1-3, resp.) and 3-methoxyviolaceol-ii (4), eight new bisabolane sesquiterpenoids, named (-)-(r)-cyclo-hydroxysydonic acid (5), (-)-(7s,8r)-8-hydroxysydowic acid (6), (-)-(7r,10s)-10-hydroxysydowic acid (7), (-)-(7r,10r)-iso-10-hydroxysydowic acid (8), (-)-12-acetoxy-1-deoxysydonic acid ( ... | 2015 | 25879502 |
| versicorin, a new lovastatin analogue from the fungus aspergillus versicolor sc0156. | a new lovastatin analogue versicorin (1), together with three related compounds, decumbenones a (2) and b (3) and versiol (4), were isolated from mycelial solid cultures of aspergillus versicolor sc0156. their structures were elucidated on the basis of ms data and nmr spectroscopic analysis. the new compound versicorin (1) possesses a hexahydro-2h-naphtho[1,8-bc]furan moiety, which is a rare type of the lovastatin-analogous compounds. a hypothetical biosynthetic pathway for compounds 1-4 was pro ... | 2015 | 25835225 |
| biodegradation of pesticide triclosan by a. versicolor in simulated wastewater and semi-synthetic media. | triclosan is known as an antimicrobial agent, a powerful bacteriostat and an important pesticide. in this paper biodegradation of triclosan by aspergillus versicolor was investigated. effects of simulated wastewater and semi-synthetic media on fungal triclosan degradation process were detected. hplc analysis showed that fungal triclosan biodegradation yield was 71.91% at about 7.5 mg/l concentration in semi-synthetic medium and was 37.47% in simulated wastewater. fungus could be able to tolerate ... | 2015 | 25752427 |
| versicolols a and b, two new prenylated isocoumarins from endophytic fungus aspergillus versicolor and their cytotoxic activity. | versicolols a and b (1 and 2), two rare prenylated isocoumarin derivatives, along with five known isocoumarins (3-7) were isolated from the fermentation products of an endophytic fungus aspergillus versicolor. their structures were elucidated on the basis of extensive spectroscopic analysis, including 1d- and 2d-nmr techniques. compounds 1 and 2 were evaluated for their cytotoxicity against five human tumor cell lines. the results showed that compounds 1 exhibited weak cytotoxicity against a549 ... | 2017 | 25749845 |
| antiviral butyrolactones from the endophytic fungus aspergillus versicolor. | versicolactones a-d (1-4), four new butyrolactones, along with four known butyrolactones (5-8) were isolated from the fermentation products of the endophytic fungus aspergillus versicolor. the structures of compounds 1-4, including absolute configuration, were elucidated by interpretation of the nmr and cd data. compound 2 was further confirmed by single-crystal x-ray diffraction analysis. in particular, compound 1 is the first naturally occurring butyrolactone possessing an unusual 2-oxopropyl ... | 2015 | 25590371 |
| effects of fungal species, cultivation time, growth substrate, and air exposure velocity on the fluorescence properties of airborne fungal spores. | real-time bioaerosol monitoring is possible with fluorescence based instruments. this study provides information on major factors that can affect the fluorescence properties of airborne fungal spores. two fluorescence-based bioaerosol detectors, bioscout, and ultraviolet aerodynamic particle sizer (uvaps), were used to study fluorescent particle fractions (fpfs) of released spores of three fungal species (aspergillus versicolor, cladosporium cladosporioides, and penicillium brevicompactum). two ... | 2015 | 25292152 |
| psychrophilins e-h and versicotide c, cyclic peptides from the marine-derived fungus aspergillus versicolor zln-60. | four new cyclic peptides, psychrophilins e-h (1-4), possessing a rare amide linkage between the carboxylic acid in anthranilic acid (ata) and the nitrogen from an indole moiety, along with a new ata-containing hexapeptide, versicotide c (5), were obtained from the culture of the marine-derived fungus aspergillus versicolor zln-60. the structures, including absolute configurations, were elucidated by a combination of hresims, nmr, x-ray crystallography, tddft ecd calculations, and marfey's method ... | 2014 | 25246036 |
| aspergillines a-e, highly oxygenated hexacyclic indole-tetrahydrofuran-tetramic acid derivatives from aspergillus versicolor. | aspergillines a-e (1-5) are highly oxygenated cyclopiazonic acid (cpa)-derived alkaloids bearing a rigid and sterically congested hexacyclic indole-tetrahydrofuran-tetramate scaffold, isolated from the endophytic fungus aspergillus vesicolor. apergillines a-c represent a new subclass of cpa-derived alkaloids, and aspergillines b and e possess a butanoic acid methyl ester moiety. the structures, including absolute configuration, were elucidated by interpretation of the nmr, x-ray crystallographic ... | 2014 | 25226561 |
| biodegradation and utilization of 4-n-nonylphenol by aspergillus versicolor as a sole carbon and energy source. | 4-n-nonylphenol (4-n-np) is an environmental pollutant with endocrine-disrupting activities that is formed during the degradation of nonylphenol polyethoxylates, which are widely used as surfactants. utilization of 4-n-np by the filamentous fungus aspergillus versicolor as the sole carbon and energy source was investigated. by means of gas chromatography-mass spectrometry, we showed that in the absence of any carbon source other than 4-n-np in the medium, a. versicolor completely removed the xen ... | 2014 | 25222932 |
| aspergilloma caused by aspergillus versicolor. | | 2014 | 25222316 |
| total synthesis of aspeverin via an iodine(iii)-mediated oxidative cyclization. | the first total synthesis of aspeverin, a prenylated indole alkaloid isolated from aspergillus versicolor in 2013, is described. key steps utilized to assemble the core structure of the target include a highly diastereoselective diels-alder reaction, a curtius rearrangement, and a unique strategy for installation of the geminal dimethyl group. a novel iodine(iii)-initiated cyclization was then used to install the bicyclic urethane linkage distinctive to the natural product. | 2014 | 25171639 |
| prenylated indole diketopiperazines from the marine-derived fungus aspergillus versicolor. | seven new prenylated indole diketopiperazines, versicamides a-g (1-7) and a novel chemical derivative from 7, versicamide h (8), along with three known analogic diketopiperazines (9-11) were obtained from the marine-derived fungus aspergillus versicolor hdn08-60. their structures were determined by spectroscopic techniques, including 2d nmr, ecd calculations, and single-crystal x-ray diffraction analysis, together with the assistance of further chemical conversions. the cytotoxicities of 1-8 wer ... | 2014 | 25089636 |
| activation of dormant secondary metabolite production by introducing neomycin resistance into the deep-sea fungus, aspergillus versicolor zby-3. | a new ultrasound-mediated approach has been developed to introduce neomycin-resistance to activate silent pathways for secondary metabolite production in a bio-inactive, deep-sea fungus, aspergillus versicolor zby-3. upon treatment of the zby-3 spores with a high concentration of neomycin by proper ultrasound irradiation, a total of 30 mutants were obtained by single colony isolation. the acquired resistance of the mutants to neomycin was confirmed by a resistance test. in contrast to the zby-3 ... | 2014 | 25076061 |
| susceptibility of green and conventional building materials to microbial growth. | green building materials are becoming more popular. however, little is known about their ability to support or limit microbial growth. the growth of fungi was evaluated on five building materials. two green, two conventional building materials and wood as a positive control were selected. the materials were inoculated with aspergillus versicolor, cladosporium cladosporioides and penicillium brevicompactum, in the absence and presence of house dust. microbial growth was assessed at four different ... | 2015 | 24975616 |
| [trichophyton rubrum onychomycosis with secondary aspergillus versicolor infection in a 12-year-old girl: successful topical therapy with terbinafine-urea ointment]. | a 12-year-old with a functional circulatory disturbance had toe nail onychomycosis caused by trichophyton rubrum. there were no other underlying diseases. | 2014 | 24817253 |
| metabolites from aspergillus versicolor, an endolichenic fungus from the lichen lobaria retigera. | three new anthraquinone derivatives (1-3) and one new artifact (4) were isolated, along with six known anthraquinone derivatives (5-10) and three xanthones (11-13), from a culture of an endolichenic fungus, aspergillus versicolor, that was isolated from the lichen lobaria retigera. the structures of these substances were determined on the basis of 1d and 2d (cosy, hmqc, and hmbc) nmr and ms analyses. the substances 1-4 were also tested for their cytotoxic activity. | 2014 | 24815583 |
| nucleoside derivatives from the marine-derived fungus aspergillus versicolor. | four nucleoside derivatives (1-4) were isolated from the fungus aspergillus versicolor derived from the gorgonian dichotella gemmacea collected in the south china sea. their structures were elucidated by comprehensive spectroscopic method of nmr and ms analysis. all isolated metabolites were evaluated for their cytotoxicity, antibacterial activity and lethality towards brine shrimp artemia salina. compounds 1/2 exhibited selective antibacterial activity against staphylococcus epidermidis with an ... | 2014 | 24670197 |
| enhanced production of cellulose degrading cmcase by newly isolated strain of aspergillus versicolor. | production of cmcase from newly isolated strain of aspergillus versicolor was studied by optimizing different physico-chemical parameters. cellulolytic potential of the isolate was confirmed by the simple agar plate method and then subjected to variation of a single parameter at a time in cmc containing medium. maximum enzyme production was obtained at 30°c in 120 h when medium was supplemented with 0.5 gm% carboxymethyl cellulose, 0.2 gm% tween 80, 0.075 gm% peptone, 0.050 gm% cacl2, 1.5 gm% na ... | 2014 | 24607178 |
| endotoxin, ergosterol, fungal dna and allergens in dust from schools in johor bahru, malaysia- associations with asthma and respiratory infections in pupils. | there are few studies on associations between respiratory health and allergens, fungal and bacterial compounds in schools in tropical countries. the aim was to study associations between respiratory symptoms in pupils and ethnicity, chemical microbial markers, allergens and fungal dna in settled dust in schools in malaysia. totally 462 pupils (96%) from 8 randomly selected secondary schools in johor bahru, malaysia, participated. dust was vacuumed from 32 classrooms and analysed for levels of di ... | 2014 | 24523884 |
| studies on the biosynthesis of chetomin: enantiospecific synthesis of a putative, late-stage biosynthetic intermediate. | the enantiospecific synthesis of desthiochetomin, a putative biosynthetic intermediate of the epidithiodioxopiperazine natural product chetomin, is described. a diastereoselective n-alkylation was employed to form the key c3-n1' bond of the heterodimeric indoline core, followed by peptide coupling and dioxopiperazine cyclization with the requisite n-methyl amino acids. a related sarcosine-derived dioxopiperazine was prepared in the same manner. the first proposed biosynthesis of chetomin is also ... | 2013 | 24489414 |
| three new sterigmatocystin analogues from marine-derived fungus aspergillus versicolor mf359. | during the systematic screening of active compounds from marine-derived fungi, the extract of a strain of aspergillus versicolor mf359 isolated from a marine sponge of hymeniacidon perleve was identified for detailed chemical investigation. three new secondary metabolites, named hemiacetal sterigmatocystin (1), acyl-hemiacetal sterigmatocystin (2), and 5-methoxydihydrosterigmatocystin (3), together with a known compound, aversin (4), were characterized. 1 represents a first structure of sterigma ... | 2014 | 24458562 |
| cytotoxic polyphenols from a sponge-associated fungus aspergillus versicolor hmp-48. | a new dibenzo[1,4]dioxin 1, and two new prenylated diphenyl ethers, 2 and 3, together with six known compounds, 4-9, were isolated from a sponge-associated fungus aspergillus versicolor hmp-f48 by bioactivity-guided fractionation. their structures were elucidated by 1d- and 2d-nmr, and ms analyses. the compounds showed potent cell growth inhibitory activities against hl-60 cell line. | 2014 | 24443433 |
| ex vivo cytokine release and pattern recognition receptor expression of subjects exposed to dampness: pilot study to assess the outcome of mould exposure to the innate immune system. | in rooms with moisture damage, the indoor air can be enriched with microorganisms causing a variety of symptoms. due to the highly diverse composition of bioaerosols and the multiple effects on humans, an assessment of the health risk is not sufficiently possible. the aim of this study was to characterize the features of innate immunity using blood from subjects exposed to moisture damage compared to control subjects living in houses without visible moisture damage. we investigated the expressio ... | 2013 | 24340055 |
| evaluation of biotechnological potentials of some industrial fungi in economical lipid accumulation and biofuel production as a field of use. | considering the vast number of scientific reports on various potential uses of fungi, there was an attempt to select the best lipid producer of some fungi at optimized conditions (aspergillus versicolor, rhizopus oryzae, rhizopus arrhizus, tramates versicolor). the aim was to offer new fields of use to the industries already culturing and using such materials. aspergillus versicolor mycelia were found to be accumulating the highest amount of lipids. experiments to improve lipid accumulation and ... | 2014 | 24320234 |
| occupational exposure to aflatoxin b1 in swine production and possible contamination sources. | although the adverse health consequences of ingestion of food contaminated with aflatoxin b1 (afb1) are known, relatively few studies are available on the adverse effects of exposure in occupational settings. taking this into consideration, our study was developed aiming to elucidate the possible effects of occupational exposure to afb1 in portuguese swine production facilities using a specific biomarker to assess exposure to afb1. in total, 28 workers participated in this study, providing blood ... | 2013 | 24156697 |
| [the effect of low radiation doses on the growth of aspergillus versicolor and paecilomyces lilacinus]. | peculiarities of growth of the strains of two species of microscopic fungi aspergillus versicolor and paecilomyces lilacinus were analyzed under exposure to chronic irradiation. it was shown that the rate of radial growth increased nonuniformly in the range of doses from 0 to 250 mgy but with maximums at a certain dose of radiation. it was shown that the absorbed dose of radiation to 2 gy did not influence the survival of investigated strains in comparison with the control ones without irradiati ... | 2013 | 24006782 |
| solid-state fermentation of jatropha seed cake for optimization of lipase, protease and detoxification of anti-nutrients in jatropha seed cake using aspergillus versicolor cjs-98. | this study focused on the solid-state fermentation of jatropha seed cake (jsc), a byproduct generated after biodiesel production. presence of anti-nutritional compounds and toxins restricts its application in livestock feed. the disposal of the jsc is a major environmental problem in the future, due to the generation of huge quantity of jsc after biodiesel extraction. hence the jsc was assessed for its suitability as substrate for production and optimization of lipase and protease from aspergill ... | 2014 | 23958640 |
| diorcinols b-e, new prenylated diphenyl ethers from the marine-derived fungus aspergillus versicolor zln-60. | four new prenylated diphenyl ethers (1-4), diorcinols b-e, together with one known diorcinol (5), were obtained from the marine-derived fungus aspergillus versicolor. their structures were established on the basis of chemical and spectroscopic data. the absolute configurations of compounds 1 and 2 were determined by mosher's ester and specific rotation analysis. their cytotoxicities were evaluated using a-549, hela, bel-7402 and k562 cell lines. compound 3 exhibited moderate cytotoxicities again ... | 2013 | 23677033 |
| a new immunoassay to quantify fungal antigens from the indoor mould aspergillus versicolor. | aspergillus versicolor is among the most commonly found moulds in moisture-damaged buildings and can be associated with adverse health effects in humans. this paper reports the development, validation and application of an enzyme immunoassay to quantify a. versicolor antigens. a sandwich elisa was developed using polyclonal antibodies that recognize a broad range of a. versicolor proteins present in fungal spores and in mycelia fragments. to validate the new method, a. versicolor antigens were q ... | 2013 | 23674292 |
| aspeverin, a new alkaloid from an algicolous strain of aspergillus versicolor. | a novel carbamate- and cyano-containing alkaloid, aspeverin (1), was isolated from the culture of an algicolous aspergillus versicolor strain (dl-29). the structure and absolute configuration were unambiguously identified by nmr, ir, ecd, and mass spectrometric methods as well as quantum chemical calculations. 1 exhibited potent bioactivities against some marine-derived organisms. | 2013 | 23650962 |
| furry pet allergens, fungal dna and microbial volatile organic compounds (mvocs) in the commercial aircraft cabin environment. | there has been concern about the cabin environment in commercial aircraft. we measured cat, dog and horse allergens and fungal dna in cabin dust and microbial volatile organic compounds (mvocs) in cabin air. samples were collected from two european airline companies, one with cabins having textile seats (tsc) and the other with cabins having leather seats (lsc), 9 airplanes from each company. dust was vacuumed from seats and floors in the flight deck and different parts of the cabin. cat (fel d1 ... | 2013 | 23644832 |
| fungal contamination in swine: a potential occupational health threat. | poor air quality in a pig-confinement building may potentially place farmers at higher health risk than other workers for exposure to airborne pollutants that may reach infectious levels. the aim of this study was to assess worker exposure to fungi in indoor environments in portuguese swine buildings. air samples from 7 swine farms were collected at a flow rate of 140 l/min, at 1 m height, onto malt extract agar supplemented with chloramphenicol (mea). surfaces samples of the same indoor sites w ... | 2013 | 23514069 |
| structural elucidation of an extracellular polysaccharide produced by the marine fungus aspergillus versicolor. | a homogenous extracellular polysaccharide, designated awp, was isolated from the fermented liquid of the marine fungus aspergillus versicolor from the coral cladiella sp. and purified by anion-exchange and size-exclusion chromatography (sec). chemical and spectroscopic analyses, including one- and two-dimensional nuclear magnetic resonance (1d and 2d nmr) spectroscopy showed that awp consisted of glucose and mannose in a molar ratio of 8.6:1.0, and its average molecular weight was estimated to b ... | 2013 | 23499086 |
| synthesis and bioconversions of notoamide t: a biosynthetic precursor to stephacidin a and notoamide b. | in an effort to further elucidate the biogenesis of the stephacidin and notoamide families of natural products, notoamide t has been identified as the likely precursor to stephacidin a. the total synthesis of notoamide t is described along with it is c-6-epimer, 6-epi-notoamide t. the chemical conversion of stephacidin a to notoamide t by reductive ring opening is described as well as the oxidative conversion of notoamide t to stephacidin a. furthermore, [(13)c](2)-notoamide t was synthesized an ... | 2013 | 23249380 |
| bioactive anthraquinones from endophytic fungus aspergillus versicolor isolated from red sea algae. | the marine fungus aspergillus versicolor was isolated from the inner tissue of the red sea green alga halimeda opuntia. the fungus was identified by its morphology and 18s rdna. cultivation of this fungal strain led to a new metabolite named isorhodoptilometrin-1-methyl ether (1) along with the known compounds emodin (2), 1-methyl emodin (3), evariquinone (4), 7-hydroxyemodin 6,8-methyl ether (5), siderin (6), arugosin c (7), and variculanol (8). the structures were elucidated on the basis of nm ... | 2012 | 23139125 |
| anthraquinone derivatives produced by marine-derived fungus aspergillus versicolor en-7. | the new anthraquinone derivative, 6,8-di-o-methylaverantin (1), together with six known congeners (2-7), were characterized from a culture extract of the marine algous fungus, aspergillus versicolor en-7. their structures were elucidated by spectroscopic methods. a bioassay showed compounds 1, 2 and 5 to have weak inhibition against escherichia coli, while compound 5 also displayed weak inhibition against staphylococcus aureus. | 2012 | 22972319 |
| brevianamides with antitubercular potential from a marine-derived isolate of aspergillus versicolor. | an aspergillus versicolor isolated from sediment collected from the bohai sea, china, yielded the new dimeric diketopiperazine brevianamide s (1), together with three new monomeric cometabolites, brevianamides t (2), u (3), and v (4). structures were determined by detailed spectroscopic analysis. brevianamide s exhibited selective antibacterial activity against bacille calmette-guérin (bcg), suggestive of a new mechanism of action that could inform the development of next-generation antitubercul ... | 2012 | 22963079 |
| dectin-1 and il-17a suppress murine asthma induced by aspergillus versicolor but not cladosporium cladosporioides due to differences in β-glucan surface exposure. | there is considerable evidence supporting a role for mold exposure in the pathogenesis and expression of childhood asthma. aspergillus versicolor and cladosporium cladosporioides are common molds that have been implicated in asthma. in a model of mold-induced asthma, mice were repeatedly exposed to either a. versicolor or c. cladosporioides spores. the two molds induced distinct phenotypes, and this effect was observed in both balb/c and c57bl/6 strains. c. cladosporioides induced robust airway ... | 2012 | 22962686 |
| bioremoval of textile dyes with different chemical structures by aspergillus versicolor in molasses medium. | bioremoval of 17 dyes with different chemical structures by aspergillus versicolor was detected in this study. maxilon red grl (mr-grl), everdirect fast black vsf (efb-vsf) and brillant blue r (bb-r) were removed better by fungal mycelia. optimum ph values were found as 6 for all three dyes. in further experiments in the highest dye concentrations tested in this study, 58.3, 100 and 49% removal yields and 14.8, 12.6, 9.0 q(m) values were found for mr-grl, efb-vsf and bb-r, respectively. chemical ... | 2012 | 22949249 |
| a new sesquiterpene from an endophytic aspergillus versicolor strain. | a new sesquiterpene, albican-1,14-diol (1), and seven known compounds, including sterigmatocystin (2), 3-hydroxy-5-(hydroxymethyl)-4-(4'-hydroxyphenoxy) pyrrolidin-2-one (3), (1h-indol-3-yl) oxoacetamide (4), indole-3-carboxylic acid (5), indole-3-acetic acid (6), indole-3-carboxaldehyde (7), and volemolide (8), were isolated from the cultures of aspergillus versicolor, an endophytic fungus isolated from the marine green alga codium fragile. the structure of 1 was elucidated by 1d, 2d nmr and ma ... | 2012 | 22908554 |
| isotherm and kinetic models and cell surface analysis for determination of the mechanism of metal sorption by aspergillus versicolor. | the isolate aspergillus versicolor was obtained from an estuary, which is exposed to metal contamination. it was found to have a good metal tolerance and sorption capacity. further studies revealed that the rate of metal removal from solution is very rapid in the first 5-10 min, and is favoured by a ph of 6.0. the biosorption data obtained was explained by the freundlich adsorption isotherm model and followed a pseudo-second order kinetics reaction. the fungus showed a higher accumulation of fat ... | 2012 | 22806158 |
| effect of two aerosolization methods on the release of fungal propagules from a contaminated agar surface. | the effect of perpendicular and swirling aerozolization methods on the release of fungal fragments and spores from agar surface was studied. three fungal species (aspergillus versicolor, cladosporium cladosporioides, penicillium chrysogenum) were selected for the tests as they commonly occur indoors, create different hyphae structure when they grow on surfaces, and have different spore shapes, aerodynamic sizes, and formation mechanisms. as the tested surface, petri dishes filled with malt extra ... | 2012 | 22742802 |
| identification of a brevianamide f reverse prenyltransferase brept from aspergillus versicolor with a broad substrate specificity towards tryptophan-containing cyclic dipeptides. | a putative brevianamide f reverse prenyltransferase gene brept was amplified from aspergillus versicolor nrrl573 by using primers deduced from its orthologue notf in aspergillus sp. mf297-2 and overexpressed in escherichia coli. the soluble his-tagged protein brept was purified to near homogeneity and assayed with tryptophan-containing cyclic dipeptides in the presence of dimethylallyl diphosphate. brept showed much higher flexibility towards its aromatic substrates than notf and accepted all of ... | 2013 | 22660767 |
| cytotoxicity and genotoxicity of versicolorins and 5-methoxysterigmatocystin in a549 cells. | aspergillus versicolor and a. flavus are primary colonizers in damp dwellings, and they produce sterigmatocystin (st) and aflatoxin b1 (afb(1)), respectively. these hepatotoxic and carcinogenic mycotoxins and their precursors and derivates possess a furofuran ring, which has proven responsible for their toxicity. the aim of this study was to investigate the cytotoxicity and genotoxicity of versicolorin a (ver a) and versicolorin b (ver b), as the furofuran precursors of aflatoxins and st, and of ... | 2012 | 22648070 |
| effects of onion (allium cepa l.) and garlic (allium sativum l.) essential oils on the aspergillus versicolor growth and sterigmatocystin production. | in the present study the effects of individual and combined essential oils (eos) extracted from onion (allium cepa l.) bulb and garlic (allium sativum l.) clove on the growth of aspergillus versicolor and sterigmatocystin (stc) production were investigated. the eos obtained by hydrodistillation were analyzed by gc/ms. twenty one compounds were identified in onion eo. the major components were: dimethyl-trisulfide (16.64%), methyl-propyl-trisulfide (14.21%), dietil-1,2,4-tritiolan (3r,5s-, 3s,5s- ... | 2012 | 22497489 |
| microbiological evaluation of ten french archives and link to occupational symptoms. | fungi that damage documents in archives may harm workers' health, depending on which mold species are inhaled, the concentrations of fungal species inhaled, and individual factors. our aim was to identify and quantify fungi in archives and to investigate possible links with the symptoms experienced by workers. ten french archives were sampled using an air impactor and electrostatic dust collectors. allergies and general symptoms felt by 144 workers were reported using a self-report questionnaire ... | 2012 | 22429323 |
| secondary metabolites from an algicolous aspergillus versicolor strain. | two new compounds, asperversin a (1) and 9ξ-o-2(2,3-dimethylbut-3-enyl)brevianamide q (2), and nine known compounds, brevianamide k (3), brevianamide m (4), aversin (5), 6,8-di-o-methylnidurufin (6), 6,8-di-o-methylaverufin (7), 6-o-methylaverufin (8), 5α,8α-epidioxyergosta-6,22-dien-3β-ol (9), ergosta-7,22-diene-3β,5α,6β-triol (10), and 6β-methoxyergosta-7,22-diene-3β,5α-diol (11), were obtained from the culture of aspergillus versicolor, an endophytic fungus isolated from the marine brown alga ... | 2012 | 22363226 |
| remediation of mould damaged building materials--efficiency of a broad spectrum of treatments. | we compared the efficiency of some commercially available products and methods used for remediation of mould-contaminated building materials. samples of gypsum board and pinewood were artificially contaminated with toxin-producing isolates of stachybotrys chartarum and aspergillus versicolor, respectively, then, ten different remediation treatments were applied according to the manufacturers' instructions. microbial and chemical analyses of the infested materials were carried out both immediatel ... | 2012 | 22286589 |
| comparison of dna extraction methodologies used for assessing fungal diversity via its sequencing. | traditional methods of assessing fungal exposure have been confounded by a number of limiting variables. the recent utilization of molecular methods such as internal transcribed spacer (its) sequencing of ribosomal rna genes has provided improved insight into the diversity of fungal bioaerosols in indoor, outdoor and occupational environments. however, its analyses may also be confounded by a number of methodological limitations. in this study, we have optimized this technology for use in occupa ... | 2012 | 22230933 |
| sterigmatocystin presence in typical latvian grains. | ninety five samples of different latvian grains (wheat, buckwheat, barley, oats and rye) from the year 2006 and 120 samples from the year 2007 were analyzed for aspergillus ssp. mycotoxin-sterigmatocystin (stc) content. 13.7% of the analyzed 2006 year samples were positive for stc with the concentration levels ranging from <0.7 to 83μg/kg and 35% of the analyzed 2007 year samples were positive for stc with the concentration levels ranging from <1 to 47μg/kg. a previously developed sensitive lc - ... | 2008 | 26054287 |
| fermentation of millet to produce kamu a nigerian starch-cake food. | microorganisms present in the unfermented grains of millet at the initial stage of steeping and after sieving at the initial stage of souring for the preparation of kamu were moulds (aspergillus versicolor, penicillim nigricans and rhizopus stolonifer), bacteria (pediococcus pentosaceus and lactobaclllus plantarum) and a yeast (saccharomyces cerevisiae). only the bacteria and yeast persisted to the end of the steeping period. these, together with another yeast, candida krusel, brought about the ... | 1991 | 24424932 |
| investigation of inflammatory and allergic responses to common mold species: results from in vitro experiments, from a mouse model of asthma, and from a group of asthmatic patients. | most studies on molds focus on alternaria alternata and aspergillus fumigatus. here, we report on inflammatory and allergenic properties of more typical indoor species aspergillus versicolor, p. chrysogenum, c. cladosporioïdes, and c. sphaerospermum that were compared to a. alternata and a. fumigatus. in a mouse model, after intranasal instillation, a. alternaria, a. versicolor, and c. sphaerospermum induced the early recruitment of neutrophils and the strong expression of inflammatory markers i ... | 2017 | 28370571 |
| free chlorine and monochloramine inactivation kinetics of aspergillus and penicillium in drinking water. | fungi are near-ubiquitous in potable water distribution systems, but the disinfection kinetics of commonly identified fungi are poorly studied. in the present study, laboratory scale experiments were conducted to evaluate the inactivation kinetics of aspergillus fumigatus, aspergillus versicolor, and penicillium purpurogenum by free chlorine and monochloramine. the observed inactivation data were then fit to a delayed chick-watson model. based on the model parameter estimation, the ct values (in ... | 2017 | 28501787 |
| antimicrobial activity and chemical composition of brunfelsia uniflora flower oleoresin extracted by supercritical carbon dioxide. | brunfelsia genus is traditionally utilized in popular medicine due to its antibacterial and antifungal properties to name but a few. however, studies on the antimicrobial activity of brunfelsia uniflora flower oleoresin have not been found yet. this study aimed to evaluate the chemical composition and antimicrobial activity of b. uniflora flower oleoresin obtained by supercritical carbon dioxide. oleoresin from the plant dried flowers was obtained by carbon dioxide, and the chemical composition ... | 2017 | 28407186 |
| [a new cytotoxic isocoumarin from endophytic fungus aspergillus versicolor]. | a new isocoumarin, along with five known ones,were isolated from the fermentation products of an endophytic fungus aspergillus versicolorby using various chromatographic techniques.their structures were elucidated on the basis of extensivespectroscopic analysis, including 1d-and 2d-nmr techniques. compound 1 was evaluated for cytotoxicity against five human tumor cell lines. the results showed that 1 exhibited weak cytotoxicityagainst nb4, shsy5y and mcf7 cells with ic₅₀ values of 6.8, 4.3,8.8 μ ... | 2016 | 28845647 |
| contribution of filamentous fungi to the musty odorant 2,4,6-trichloroanisole in water supply reservoirs and associated drinking water treatment plants. | in this study, the distribution of 2,4,6-trichloroanisole (2,4,6-tca) in two water supply reservoirs and four associated drinking water treatment plants (dwtps) were investigated. the 2,4,6-tca concentrations were in the range of 1.53-2.36 ng l(-1) in water supply reservoirs and 0.76-6.58 ng l(-1) at dwtps. to determine the contribution of filamentous fungi to 2,4,6-tca in a full-scale treatment process, the concentrations of 2,4,6-tca in raw water, settled water, post-filtration water, and fini ... | 2017 | 28499183 |
| antimicrobial activity and molecular docking studies of a novel anthraquinone from a marine-derived fungus aspergillus versicolor. | a novel anthraquinone, 2-(dimethoxymethyl)-1-hydroxyanthracene-9,10-dione (1), together with nine known compounds (2-10), were isolated from the fermentation of aspergillus versicolor derived from deep sea sediment. their structures were established through spectroscopic methods. compound 1 exhibited strong inhibitory activities against mrsa atcc 43300 and mrsa cgmcc 1.12409 (with mic values of 3.9 and 7.8 μg/ml respectively) and moderate activities against tested strains of vibrio (with mic val ... | 2017 | 28511613 |
| antifungal and antiviral cyclic peptides from the deep-sea-derived fungus simplicillium obclavatum eiodsf 020. | a new linear peptide simplicilliumtide i (1) and four new cyclic peptides simplicilliumtides j-m (2-5) together with known analogues verlamelins a and b (6 and 7) were isolated from the deep-sea-derived fungal strain simplicillium obclavatum eiodsf 020. their structures were elucidated by spectroscopic analysis, and their absolute configurations were further confirmed by chemical structural modification, marfey's and mosher's methods. compounds 2, 6, and 7 showed significant antifungal activity ... | 2017 | 28578573 |
| aerosolization of mycotoxins after growth of toxinogenic fungi on wallpaper. | many fungi can develop on building material in indoor environments if moisture is high enough. among species that are frequently observed, some are known to be potent mycotoxin producers. this presence of toxinogenic fungi in indoor environments raises the question of the possible exposure of occupants to these toxic compounds by inhalation after aerosolization.this study investigated the mycotoxin production by penicillium brevicompactum, aspergillus versicolor and stachybotrys chartarum during ... | 2017 | 28646113 |
| ecology and identification of environmental fungi and metabolic processes involved in the biodeterioration of brazilian soapstone historical monuments. | the present study aimed to evaluate the action of organic acids produced by the fungal population associated with the biodeterioration process of the twelve prophets of aleijadinho, a set of soapstone sculptures in congonhas, state of minas gerais, brazil. for this, samples of fungi were obtained from the surface of each of the twelve outdoor stone sculptures that comprise the set of prophets. identification of the colonizing filamentous fungi was performed by classical microbiology and molecula ... | 2017 | 28833313 |