| herd problem of abortions and malformed calves attributed to bovine viral diarrhea. | a herd problem of abortions and the birth of malformed calves developed subsequent to a transient febrile illness in adult cows. the herd was not vaccinated against bovine viral diarrhea (bvd). bovine viral diarrhea virus was isolated from blood of one calf. the problem continued for 8 months. the entire herd was vaccinated with a killed bvd virus product. no further problems developed. this herd problem illustrates one of the many recognized clinical manifestations of bvd. | 1986 | 3957770 |
| bovine viral diarrhea in a newborn calf. | bovine viral diarrhea virus was believed to be the cause of ill-thrift since birth, resulting in death of a holstein calf. bovine viral diarrhea virus was isolated from peyer's patches and mesenteric lymph nodes, but serum neutralizing antibodies were not detected. the lymphoid depletion and myeloid suppression seen in this case may be a factor in the immune system dysfunction described for bovine viral diarrhea. typical ulcerative lesions within the alimentary tract were not observed. | 1985 | 3988595 |
| morphometric studies of the bovine uterus: microscopic lesions and retrospective reproductive history. | a survey of reproductive tracts from nonpregnant cows at an abattoir was conducted. reproductive tracts from 98 cows were studied microscopically and evaluated with a grading system to determine the severity of pathologic changes. inflammatory reaction (type and distribution), fibrosis, gland morphology, and appearance were measured, quantified, and scored (1 to 4). category 1 endometrium (normal) was found in 18 cows, category 2 in 23, category 3 in 34, and category 4 in 23. the category of end ... | 1985 | 4083598 |
| studies on bovine viral diarrhea-mucosal disease virus. ii. stability and some physico-chemical properties. | | 1972 | 4116923 |
| electron optical studies of bovine viral diarrhea-mucosal disease virus (bvdv). | | 1970 | 4192473 |
| characterization of bovine viral diarrhea viruses. v. morphology of characteristic particles studied by electron microscopy. | | 1969 | 4195624 |
| border disease-like syndrome in lambs: antibodies to hog cholera and bovine viral diarrhea viruses. | | 1973 | 4201826 |
| a hazy ('bull's eye') plaque variant of bovine viral diarrhea virus. | | 1974 | 4212887 |
| bovine viral diarrhea virus and escherichia coli in neonatal calf enteritis. | this study was initiated to determine the etiologic and pathogenic significance of an american strain of bovine viral diarrhea (bvd) virus (strain nadl-md) in enteritis of neonatal calves (calf scours). three colostrum-fed calves from dams exposed intravenously to bvd virus at 6, 16 and 25 days prepartum, respectively, had moderate diarrhea persisting until the eighth day of life. the bvd virus was isolated from all 3 calves and persisted up to 93 days in 1 calf, indicating either that bvd was t ... | 1968 | 4233834 |
| a study of bovine virus diarrhea mucosal disease virus by plaque technique. | bovine virus diarrhea-mucosal disease (bvd-md), nadl, strain formed 3-4 mm plaques on monolayers of bovine embryo kidney (bek), lung and testicular (bet) cell cultures on post inoculation day four. plaques were 1.5 mm on the post inoculation day five in lamb testicular cell cultures. neutral red incorporated in first overlay had inhibitory effect on plaque formation in these cell-virus systems. the study of effects of environmental variables on plaquing efficiency indicated that virus adsorption ... | 1969 | 4242771 |
| bovine viral diarrhea virus in swine: characteristics of virus recovered from naturally and experimentally infected swine. | a noncytopathogenic field strain of bovine viral diarrhea virus (bvdv) was isolated from an iowa farm brood sow and from her hysterectomy-derived, colostrum-deprived (hdcd) piglets. this field isolant was fully virulent for a neonatal calf. the nadl strain of bvdv was passaged through a series of hdcd piglets with no resultant loss of virulence for neonatal calves. most of the bvd viral isolants recovered from pigs had been changed from a cytopathogenic biotype to a noncytopathogenic biotype. ci ... | 1973 | 4265548 |
| bovine viral diarrhea virus in swine: neutralizing antibody in naturally and experimentally infected swine. | neutralizing antibodies against bovine viral diarrhea virus (bvdv) were detected in sera of iowa farm sows, their piglets derived by hysterectomy and in specific-pathogen-free (spf) pigs in a closed herd. no antibodies against bvdv were detected in sera of 134 fetal pigs from 67 sows in an iowa slaughter-house. neutralizing antibodies against bvdv or hog cholera virus, produced experimentally in spf pigs, were demonstrated to be due to different antigens rather than to a common antigen, although ... | 1973 | 4265558 |
| interference of bovine viral diarrhea virus by hog cholera virus in swine kidney cell cultures. | | 1965 | 4286768 |
| mixed infections or contaminations of bovine viral diarrhea virus with infectious bovine rhinotracheitis virus. | | 1966 | 4287980 |
| intranuclear inclusions in bovine embryo cell cultures infected with bovine virus diarrhoea-mucosal disease virus. | | 1969 | 4304013 |
| a survey of sheep throughout australia for antibody to parainfluenza type 3 virus and to mucosal disease virus. | | 1971 | 4328729 |
| pathogenetic studies of infection of the bovine fetus with bovine viral diarrhea virus. i. cerebellar atrophy. | | 1974 | 4377332 |
| studies on bovine viral diarrhea-mucosal disease virus. i. cultural behaviour and antigenic relationship of some strains. | | 1972 | 4404097 |
| bovine viral diarrhea virus: acquired resistance to acriflavine as marker of an attenuated strain. | | 1974 | 4412238 |
| comparison of low- and high-passage bovine turbinate cells for assay of bovine viral diarrhea virus. | | 1974 | 4472511 |
| effects of intrauterine inoculation of bovine viral diarrhea-mucosal disease virus on uterine tubes and uterus of nonpregnant cows. | | 1973 | 4583643 |
| abnormalities of in vitro lymphocyte responses during bovine viral diarrhea virus infection. | | 1973 | 4707560 |
| immunologic response of bovine fetus to bovine viral diarrhea virus. | | 1973 | 4747033 |
| virus induced congenital anomalies of the bovine fetus. i. cerebellar degeneration (hypoplasia), ocular lesions and fetal mummification following experimental infection with bovine viral diarrhea-mucosal disease virus. | | 1973 | 4748881 |
| the replication of bovine viral diarrhea-mucosal disease virus in bovine leukocytes in vitro. | | 1973 | 4749260 |
| separation of structural proteins of bovine viral diarrhea virus after degradation by different splitting techniques. brief report. | | 1973 | 4796310 |
| bovine virus diarrhoea-mucosal disease virus and border disease. | | 1973 | 4807812 |
| infection of pregnant ewes with mucosal disease virus of ovine origin. | | 1974 | 4825997 |
| bovine viral diarrhea virus-host cell interactions: adaptation, propagation, modification, and detection of virus in rabbits. | | 1969 | 4896229 |
| bovine viral diarrhea virus-host cell interactions: adaptation and growth of virus in cell lines. | | 1969 | 4896230 |
| detection of bovine viral diarrhea virus and antigen in tissues of experimentally infected calves by cell inoculation and fluorescent antibody techniques. | | 1969 | 4898012 |
| characterization of bovine viral diarrhea viruses. iv. sequential development of bvd viral antigen in cell cultures studied by immunofluorescence. | | 1969 | 4900192 |
| adaptation of bovine viral diarrhea virus to the madin-darby bovine kidney cell line. | | 1968 | 4966759 |
| characterization of bovine viral diarrhea viruses. i. determination of buoyant density. | | 1968 | 4974542 |
| characterization of bovine viral diarrhea viruses. ii. ultrafiltration properties of different strains after various treatments. | | 1968 | 4974543 |
| characterization of bovine viral diarrhea viruses. 3. partial purification by agar gel filtration. | | 1968 | 4974544 |
| epidemiological observations on bovine viral diarrhea-mucosal disease virus-induced congenital cerebellar hypoplasia and ocular defects in calves. | | 1970 | 4986633 |
| [study by immuno-diffusion of several antigenic properties of bovine mucosal disease virus strains isolated in france]. | | 1970 | 4996323 |
| [relationships between mucosal disease, virus diarrhea and hog cholera and their significance in veterinary practice]. | | 1971 | 5000016 |
| infection of sheep with a mucosal disease virus. | | 1972 | 5013807 |
| a cytopathogenic strain of bovine viral diarrhea-mucosal disease virus isolated from a bovine fetus. | | 1972 | 5061945 |
| buoyant density of bovine viral diarrhea virus. | | 1972 | 5064488 |
| response of the bovine fetus to bovine viral diarrhea-mucosal disease virus. | | 1971 | 5115543 |
| bovine viral diarrhea-mucosal disease virus infection in pregnant cows. | | 1971 | 5164965 |
| isolation and identification of bovine viral diarrhea-mucosal disease virus (bvd-md virus) from an atypical case resembling malignant catarrhal fever (mcf). | | 1971 | 5169166 |
| bovine viral diarrhea virus: neutralizing antibodies in a calf obtained by cesarean section from cow which was infected. | | 1970 | 5414878 |
| bovine viral diarrhea virus-host cell interactions: serotypes and their relationship to biotypes by cross neutralization. | | 1971 | 5545462 |
| distribution and persistence of mucosal disease virus in experimentally exposed calves. | | 1968 | 5690779 |
| homologous interference by an actively multiplying noncytopathic strain of bovine virus diarrhea-mucosal virus. | reduction in plaque size of cytopathic strains of bovine virus diarrhea-mucosal disease virus was determined to be a more sensitive indicator than number for detecting the interference induced by the noncytopathic strain of virus in cell cultures. | 1969 | 5813679 |
| [contribution to mucosal disease--virus diarrhea-complex of cattle]. | | 1965 | 5891089 |
| comparative pathologic, immunologic, and clinical responses produced by selected agents of the bovine mucosal disease-virus diarrhea complex. | | 1965 | 5892839 |
| experimental production of fatal mucosal disease in cattle. | three outbreaks of mucosal disease were investigated. careful examination of 47 cattle that were persistently viraemic with bovine virus diarrhoea virus (bvdv) revealed no clinical disease, no or low levels of bvdv antibody and only non-cytopathic virus in their blood. the four animals with mucosal disease all showed clinical disease and both cytopathic and non-cytopathic virus in their blood. following post mortem examination, there were particularly high levels of cytopathic virus in gut tissu ... | 1984 | 6087539 |
| bovine virus diarrhoea-mucosal disease virus-induced fetopathy in cattle: efficacy of prophylactic maternal pre-exposure. | maternal immunity was produced in jersey heifers by exposing them to bovine virus diarrhoea-mucosal disease virus before conception. in the following pregnancy this immunity protected the fetuses from transplacental infection arising from challenge of the dams at 100 days gestation with homologous virus. unprotected jersey heifers showed a high incidence of death and fetal intrauterine growth retardation associated with transplacental viral infection. functional normality of the locomotor system ... | 1984 | 6087540 |
| nature of early reproductive failure caused by bovine viral diarrhea virus. | a 2-part study was undertaken to determine the effect of bovine viral diarrhea (bvd) virus on fertilization and early development of embryos. in experiment 1, 10 seronegative cows were superovulated and artificially inseminated twice during estrus. after the second insemination, 5 of the cows received intrauterine infusion of bvd virus suspension. the other 5 cows received suspending medium only and served as controls. all 10 cows were slaughtered on day 3, and ova and embryos were collected for ... | 1984 | 6088456 |
| experimental production of bovine respiratory tract disease with bovine viral diarrhea virus. | five 6-month-old calves were inoculated with bovine viral diarrhea (bvd) virus (n = 3) or pasteurella haemolytica (n = 2) endobronchially with a fiberoptic bronchoscope. five additional calves were inoculated sequentially with bvd virus followed by p haemolytica at a 5-day interval. blood samples were collected daily from the calves for bacterial isolation. clinical signs of respiratory tract disease in calves were recorded daily. if the calves survived, they were killed for necropsy 3 or 4 days ... | 1984 | 6089623 |
| prevalence of antibodies to bovine respiratory syncytial virus, bovine viral diarrhea virus, bovine herpesvirus-1, and bovine parainfluenza-3 virus in sheep and goats in quebec. | serum samples were collected from 1,075 clinically normal sheep and goats from 77 flocks in 7 agricultural regions of quebec from june to august 1982. sheep and goats were tested for antibodies to bovine respiratory syncytial virus, bovine viral diarrhea virus, and bovine herpes-virus-1 by the indirect fluorescent antibody technique and for parainfluenza-3 virus by the hemagglutination inhibition test. the prevalence of antibodies in animals to respiratory syncytial virus was 31%; to bovine vira ... | 1984 | 6089626 |
| cell-free translation of bovine viral diarrhea virus rna. | bovine viral diarrhea virus rna was translated in a reticulocyte cell-free protein synthesizing system. the purified, 8.2-kilobase, virus-specific rna species was unable to serve an an efficient message unless it was denatured immediately before translation. in this case, several polypeptides, ranging in molecular weight from 50,000 to 150,000 and most of which were immunoprecipitated by bovine viral diarrhea virus-specific antiserum, were synthesized in vitro. when polyribosomes were used to pr ... | 1984 | 6092725 |
| differentiation of cytopathic and noncytopathic isolates of bovine viral diarrhea virus by virus neutralization. | soluble antigens of cytopathic and noncytopathic isolates of bovine viral diarrhea virus were resolved by high-performance liquid gel-permeation chromatography into 4 major and 3 minor peaks. the 2 peaks with the larger molecular weights (240,000 and 140,000 daltons) were immunogenic when inoculated into rabbits. virus neutralizing antibodies were specific for the homologous virus. the soluble antigens were determined to be greater than 100,000 daltons by filtration. | 1984 | 6093646 |
| evaluation of bovine viral diarrhea virus uptake by preimplantation embryos. | bovine embryos were exposed to bovine viral diarrhea (bvd) virus in vitro. an uptake of bvd virus by the embryos could not be detected by several assay systems. a significant decrease in the titer of bvd virus was found to occur when the virus was incubated in saline solution + 5% goat serum or minimal essential medium + 5% goat serum for 24 hours at 37 c. since there was significant inactivation of the bvd virus during the incubation period, lack of viral infectivity of the embryos may have bee ... | 1984 | 6093648 |
| outbreak of mucosal disease among apparently immunotolerant heifers. | an outbreak of mucosal disease that occurred among friesian heifers aged 15 to 18 months is described as it occurred. investigation suggested that many heifers were immunotolerant to bovine virus diarrhoea-mucosal disease virus. serious losses were incurred. the present policy of surveillance is described. | 1984 | 6097016 |
| characterization of a non-cytopathogenic agent isolated from cytopathogenic bovine viral diarrhea-mucosal disease virus stock. | | 1984 | 6097801 |
| reverse plaque formation method for titration of non-cytopathogenic bovine viral diarrhea-mucosal disease virus. | the reverse plaque formation (rpf) method with a semi-micro plate was applied to the titration of a non-cytopathogenic (non-cp) strain of bovine viral diarrhea-mucosal disease (bvd-md) virus. all the five non-cp strains used in this experiment formed reverse plaques (rp) on bovine testicle cell culture under methyl cellulose overlay. the rpf was inhibited by the pretreatment of a non-cp virus strain with immune rabbit serum to a reference strain. the specificity of the rpf method was demonstrate ... | 1983 | 6097820 |
| serologic survey for selected microbial pathogens in alaskan wildlife. | antibodies to brucella spp. were detected in sera of seven of 67 (10%) caribou (rangifer tarandus), one of 39 (3%) moose (alces alces), and six of 122 (5%) grizzly bears (ursus arctos). antibodies to leptospira spp. were found in sera of one of 61 (2%) caribou, one of 37 (3%) moose, six of 122 (5%) grizzly bears, and one of 28 (4%) black bears (ursus americanus). antibodies to contagious ecthyma virus were detected in sera of seven of 17 (41%) dall sheep (ovis dalli) and five of 53 (10%) caribou ... | 1983 | 6139490 |
| factors affecting the assay of bovine type i interferon on bovine embryonic lung cells. | one preparation of interferon (if) on 7-day-old bovine embryonic lung cultures free of bovine viral diarrhea virus had titers ranging from 20 to 10,240 in plaque-reduction tests, using bovine vesicular stomatitis virus. factors believed to contribute to this variation were investigated. although titers differed on different cell strains, different passages, and on cultures of different ages, variations between the two assays definitely could not be established as a function of these factors. how ... | 1980 | 6157340 |
| factors affecting the production of bovine type i interferon on bovine embryonic lung cells by polyriboinosinic-polyribocytidylic acid. | variables believed to affect the amount of interferon (if) produced in bovine embryonic lung cell cultures by polyriboinosinic-polyribocytidylic acid (poly (ri:rc)) were investigated. a concentration of 100 micron of poly (ri:rc)/ml consistently induced substantial amounts of if. bovine viral diarrhea virus infection of cultures did not interfere with induction of if by poly (ri:rc). neither the age of cells nor the passage level of the cultures seemed to affect the amount of if produced. primin ... | 1980 | 6157341 |
| use of an immunoperoxidase stain for the demonstration of bovine viral diarrhea virus by light and electron microscopies. | bovine viral diarrhea (bvd) virus-specific antiserum eluted from an immunoabsorbent column was conjugated with horseradish peroxidase. the immunoperoxidase (ip) conjugate was used to stain bvd virus-inoculated and control tissue cultures processed for light and electron microscopies. infected cells (in the inoculated cultures) viewed by light microscopy had diffuse staining of the cytoplasm of nonvacuolated cells and a more predominant staining associated with vacuoles as vacuolation occurred. t ... | 1984 | 6200012 |
| antiviral effects of bovine interferons on bovine respiratory tract viruses. | the antiviral effects of bovine interferons on the replication of bovine respiratory tract viruses were studied. bovine turbinate monolayer cultures were treated with bovine interferons and challenged with several bovine herpesvirus 1 strains, bovine viral diarrhea virus, parainfluenza type 3 virus, goat respiratory syncytial virus, bovine respiratory syncytial virus, bovine adenovirus type 7, or vesicular stomatitis virus. treatment with bovine interferons reduced viral yield for each of these ... | 1984 | 6201505 |
| a study of serologic relationships among non-cytopathogenic strains of bovine viral diarrhea-mucosal disease virus by reverse plaque technique. | | 1984 | 6210389 |
| experimental infection of calves with two strains of bovine virus diarrhoea virus: virus recovery and clinical reactions. | fifteen calves were inoculated with a mixture of two strains of bovine virus diarrhoea virus (bvdv), the cytopathogenic nadl strain which had been passaged over 20 times n vitro, and the non-cytopathogenic fcs strain, passaged only once after isolation from fetal calf serum. in a second experiment, seven calves received the nadl strain, and eight the fcs strain. the clinical and virological results of the two experiments were compared. in dual infections, the nadl strain interfered with the repl ... | 1980 | 6246564 |
| bovine viral diarrhea infection in pregnant swine. | twenty pregnant gilts (5 groups of 4) were infected experimentally with 1 of 4 strains of bovine viral diarrhea virus (bvdv) administered intranasally-orally. blood specimens were taken from the gilts on postinfection day (pid) 7 and cultured for virus. serum specimens, obtained on pid 21 and at termination of the experiment, were tested for neutralizing antibodies. at 90 to 112 days of gestation, the gilts were euthanatized and their fetuses were examined for evidence of intrauterine infection. ... | 1980 | 6250421 |
| association of bovine viral diarrhoea-mucosal disease virus with ovaritis in cattle. | | 1980 | 6252882 |
| specific fluorescein-labeled antibodies to bovine viral diarrhea virus prepared from sera of rabbits immunized with purified virus. | specific fluorescein-labeled antibody conjugates to three strains of bovine virus diarrhea virus were prepared from hyperimmune rabbit sera. viruses used to hyperimmunize the rabbits were purified by four different procedures. conjugates were comparable in quality and specificity to conjugates prepared from serum of a calf hyperimmunized to bovine virus diarrhea virus in our laboratory. the latter conjugate was tested by biologics laboratories, national veterinary services, u.s.d.a., ames, iowa. | 1980 | 6253035 |
| bovine virus diarrhoea-mucosal disease virus: pathogenicity for the fetal calf following maternal infection. | fifteen pregnant, bovine virus diarrhoea-mucosal disease (bvd-md) antibody-free jersey heifers were infected experimentally with a mixture of 10 cytopathic strains of bvd-md virus isolated from cattle in britain. each cow was inoculated intramuscularly on gestation day 100 with a high or a low dose of virus grown in primary calf testis tissue cultures. none of the cows showed clinical signs of illness following exposure, but all had seroconverted within six weeks. six fetuses, including one set ... | 1980 | 6255660 |
| growth characteristics of two strains of bovine virus diarrhoea virus. | the replication cycles of a cytopathogenic and a non-cytopathogenic strain of bovine virus diarrhoea virus (bvdv) were similar in kinetics and the tendency of cell-free infectivity to exceed the titre of cell-associated, but differed in virus yield per cell. actinomycin d enhanced the yield of the non-cytopathogenic strain and depressed that of the cytopathogenic strain. | 1980 | 6255903 |
| survey for antibodies to viruses of bovine virus diarrhea, bluetongue, and epizootic hemorrhagic disease in hunter-killed mule deer in new mexico. | sera from male mule deer (odocoileus hemionus) collected in november 1977 in otero county, new mexico were tested fro antibodies to bovine virus diarrhea virus (bvdv), bluetongue virus (btv), and epizootic hemorrhagic disease virus (ehdv). neutralizing antibodies were detected in 26 of 76 (34%) sera tested for bvdv (titer greater than or equal to 1:16). of 46 sera tested for antibodies to btv and ehdv, 10 (22%) and 3 (7%), respectively, were positive. three (7%) of 46 sera were suspect (titer < ... | 1980 | 6256331 |
| a survey of virus infections of the respiratory tract of cattle and their association with disease. | a total of 1590 caves were investigated between may 1972 and december 1975. twenty-two per cent were treated for respiratory disease and 2 . 5% died of pneumonia. almost 80% of the respiratory illness occurred in six sharp outbreaks. samples of virology were collected routinely from 127 healthy calves and from 354 calves treated for respiratory signs and comprised 1143 nasopharyngeal swabs and 1069 sera. virus infections were detected on 540 occasions including 135 by parainfluenzavirus type 3 ( ... | 1980 | 6256435 |
| viral contamination of bovine fetal lung cultures and bovine fetal serum. | commercial bovine fetal serum (bfs) and bovine fetal lung (bfl) cells were tested for viruses. the only virus detected in any samples was noncytopathogenic bovine viral diarrhea virus (bvdv). of 37 bfl cultures initiated, 34 were negative for bvdv, 1 was positive, and 2 were suspicious in that the source of bvdv contamination was not certain. of 9 lots of irradiated sera tested, 1 (10%) was positive for bvdv; of 21 lots of nonirradiated sera tested, 13 (62%) were positive for bvdv. as judged by ... | 1980 | 6261615 |
| bovine viral diarrhea virus: affinity chromatography on crotalaria juncea lectin. | attempts were made to purify bovine viral diarrhea virus by chromatography on crotalaria juncea lectin coupled to sepharose 2b. a recovery of abut 65% of viral infectivity after desorption was obtained. electron microscopy revealed mostly de-enveloped particles, rather uniform in appearance but differing in size. immunodiffusion tests with immune calf sera showed precipitation lines of identity between the desorbed virus and extracts from infected cell cultures. | 1981 | 6262351 |
| virus-like particles in bovine turbinate cells infected with bovine virus diarrhoea/mucosal disease virus. | thin sections of bovine turbinate cells grown in culture and infected with the nadl strain of bovine virus diarrhoea/mucosal disease virus have been examined by electron microscopy. infected cells exhibited ultrastructural modification of the rough endoplasmic reticulum and associated with this small numbers of virus-like particles were observed. advanced stages of cytopathic effect were illustrated by cells showing a marked increase in electron-density. these features were not observed in uninf ... | 1981 | 6263227 |
| pathogenicity for the sheep foetus of bovine virus diarrhoea-mucosal disease virus of bovine origin. | | 1980 | 6263404 |
| early syncytium formation by bovine leukemia virus. | bovine leukemia virus (blv) from either persistently infected bat cells or fetal lamb kidney cells induced rapid syncytium formation in f81 indicator cells. distinct syncytia were seen within 2 h after inoculation of cells with highly concentrated (500-fold) cell-free blv preparations and within 4 to 8 h when unconcentrated cell-free blv preparations were used. indicator cell densities of 1 x 10(5) to 2 x 10(5) were optimal for rapid and maximal syncytium formation. pretreatment of blv with refe ... | 1981 | 6264150 |
| [complement fixation test act in the diagnosis of mucosal disease-virus diarrhea in cattle]. | experiments were made to obtain a highly active antigen for the complement-fixation test, using purification and concentration with methyl alcohol in a cell culture suspension of the causative agent of mucous disease-virus diarrhea. it was established that the cf test was sufficiently rapid and specific in the diagnosis of the disease in cattle. it proved instrumental in detecting complement-fixing antibodies in diseased and survived cattle, in calves with a latent infection and in cows with abo ... | 1980 | 6266127 |
| detection of antibodies against hog cholera virus and bovine viral diarrhea virus in porcine serum. a comparative examination using cf, pla and npla assays. | | 1981 | 6266240 |
| effects of bovine viral diarrhea virus infection on bovine polymorphonuclear leukocyte function. | four procedures were used to evaluate the function of polymorphonuclear leukocytes (pmn) isolated from the blood of cattle experimentally infected with bovine viral diarrhea (bvd) virus: (1) uptake of am emulsion of paraffin oil and escherichia coli lipopolysaccharide, (2) nitroblue tetrazolium reduction, (3) chemiluminescence, and (4) iodination, or the conversion of iodide to a trichloroacetic acid-precipitable form. a marked impairment of iodination was consistently observed after infection w ... | 1981 | 6266288 |
| effect of bovine viral diarrhea virus on conception in cattle. | sixty adult dairy cows were used to study the effect of bovine viral diarrhea (bvd) virus on conception when inoculated with the virus within 2 hours after breeding. fifteen cows were assigned at random to each of 4 groups. group i (control) cows were given 3 ml of diluent in the uterus; group ii (seropositive) cows were given 3 ml of bvd virus in the uterus; group iii (seronegative) cows were given 3 ml of bvd virus in the uterus; and group iv (seronegative) cows were given 3 ml of bvd virus or ... | 1981 | 6268584 |
| differences in reaction behaviour of structural polypeptides of bovine viral diarrhoea virus (bvdv) with antisera against bvdv and hog cholera virus (hcv). | | 1981 | 6269332 |
| in vitro and in vivo immune responses in neonatally thymectomized holstein-friesian calves exposed to bovine viral diarrhea virus. | | 1981 | 6269801 |
| bovine viral diarrhea virus (bvdv) serotiters stimulated in cattle in isolation and under field conditions by inactivated bvdv vaccine. | | 1980 | 6273923 |
| demonstration of bovine viral diarrhea virus antigen in cryostat- and paraffin-sections of bovine tissues by the immunoperoxidase technique. | an immunoperoxidase technique (ipt) for the demonstration of bovine viral diarrhea virus (bvdv) antigen in tissue sections is presented. the method was applied to cryostat sections and to alcohol fixed, paraffin embedded specimens. the specificity as well as the sensitivity of the ipt corresponded to the immunofluorescence technique (ift), and the specimen processing methods used represented an improvement of the histomorphological preservation of tissue structures. | 1981 | 6274148 |
| effects of incubation temperatures and bovine viral diarrhea virus immune serum on bovine turbinate cells persistently infected with a noncytopathogenic isolate of bovine viral diarrhea virus. | noncytopathogenic bovine viral diarrhea virus (bvdv) on initial inoculation in receptive cells induced a persistence in vitro at incubation temperatures of 33, 37, and 39 c. the mechanisms of this persistence were not the result of the induction of defective interfering particles or the selection of temperature-sensitive mutants, but were the result of a naturally occurring noncytopathogenic isolate of bvdv. persistently infected cells were not freed of the infection by continuous passage in med ... | 1981 | 6277214 |
| electron microscopic studies of bovine viral diarrhea virus in tissues of diseased calves and in cell cultures. | pathomorphological studies by electron microscopy (em) were carried out on the intestines and lymphoid tissues, the buffy coat cells and cultured lymphocytes from calves suffering from mucosal disease (md). this led to the detection of particles, 45--55 nm in diameter, within characteristic vesicular structures. as these findings coincided with the isolation of bovine viral diarrhea virus (bvdv) from the same tissues and demonstration of bvdv-antigen by immunocytochemical techniques in correspon ... | 1982 | 6279056 |
| border disease in a flock of minnesota sheep. | a flock problem affecting newborn lambs on a minnesota farm was investigated. the lambs had hairy fleece and rhythmic tremors, and were unthrifty. histologic examination revealed hypomyelinization of the cns and hypertrophy of primary follicles in the skin. a virus antigenically related to bovine viral diarrhea virus was isolated. serum neutralization showed that a large number of flock ewes had much higher titers to bovine viral diarrhea virus than did control animals. | 1982 | 6279553 |
| [on the occurrence of the viral diarrhea/mucosal disease virus in cervines in rheinland-pfalz (author's transl)]. | | 1982 | 6280950 |
| border disease virus isolation from postpartum ewes. | the prevalence of border disease virus in a flock of targhee sheep in southern idaho was determined by serologic and virologic techniques. of 249 ewes, 73 (29%) were seropositive to the antigenically related togavirus, bovine seropositive to the antigenically related togavirus, bovine viral diarrhea virus (bvdv). concurrent testing of sera from 337 neonatal lambs indicated that 172 (51%) were seropositive for bvdv. it was observed that a high percentage (35%) of the bvdv-seropositive lambs were ... | 1982 | 6283955 |
| natural cell-mediated cytotoxicity of bovine mononuclear cells against virus-infected cells. | the ability of mononuclear cells (mc) from peripheral blood of normal cattle to lyse a variety of cells was tested in a 51cr-release microcytotoxicity assay. several types of bovine cells infected with parainfluenza 3 virus (pi3v) were susceptible to natural cytotoxicity. bovine cells infected with infectious bovine rhinotracheitis virus or noncytopathogenic bovine viral diarrhea virus, uninfected bovine cells, and human cell lines molt-3, hsb-2, k562, and u-937 were not susceptible. the period ... | 1982 | 6284642 |
| prevalence of bovine herpesvirus-1, bovine oral diarrhea, parainfluenza-3, bovine adenoviruses-3 and -7, and goat respiratory syncytial viral antibodies in goats. | sera from healthy goats were collected during october 1979 through october 1980. these sera were tested for bovine herpesvirus-1 (bhv-1), bovine viral diarrhea virus (bvdv), parainfluenza-3 (pi-3) virus, bovine adenoviruses (bav) -3 and -7, and goat respiratory syncytial virus (grsv) antibodies by microtitration virus-neutralization test. the number of herds with seropositive goats for each virus were: 5/38 (13.2%) for bhv-1; 9/38 (23.7%) for bvdv; 8/38 (21.1%) for pi-3 virus; 1/38 (2.6%) for ba ... | 1982 | 6285781 |
| [attempts at isolating a precipitating antigen from a cell culture of bovine virus diarrhea-mucosal disease virus]. | | 1982 | 6287711 |
| a microtiter test for detecting and titrating noncytopathogenic bovine viral diarrhea virus. | bovine cells free of noncytopathogenic bovine viral diarrhea virus (nc-bvdv) treated with polyriboinosinic acid : polyribocytidylic acid (poly i:c) were protected against challenge with vesicular stomatitis virus (vsv), whereas nc-bvdv-infected cells treated with poly i:c were not protected against vsv. an assay based on the ability of nc-bvdv to inhibit poly i:c protection of cells against vsv was developed and is herein referred to as pinba (poly i:c for nc-bvdv assay). noncytopathogenic bvdv ... | 1982 | 6287973 |
| experimental fetal infection with bovine viral diarrhea virus. i. virological and serological studies. | the serological and virological results of an experimental infection of bovine fetuses with bovine viral diarrhea virus are presented. four fetuses, 120-165 days gestational age, were inoculated in utero with a second passage virus strain. two fetuses received a sham-inoculum. a humoral immune response in the virus-inoculated fetuses, was demonstrated three weeks later. in three fetuses only igm and igg1 were detectable. the serum from the fourth fetus also contained igg2 and iga. bovine viral d ... | 1982 | 6293687 |
| experimental fetal infection with bovine viral diarrhea virus. ii. morphological reactions and distribution of viral antigen. | the effect of an infection with bovine viral diarrhea virus on fetal bovine tissues as well as the tissue-localization of viral antigen are described. four bovine fetuses, 120-165 days of gestation, were inoculated in utero with a second passage virus strain. lymphoid tissues were studied by light and electron microscopy. the infection induced precocious development of the secondary lymphoid organs. characteristic changes were seen in postcapillary venules, cells of the mononuclear phagocyte sys ... | 1982 | 6293688 |