chicken embyro lethal orphan (celo) virus dna present in hamster cell lines derived from celo-induced hepatomas. | the kinetics of renaturation of the isolated dna fragments of chicken embryo lethal orphan (celo) virus generated by the restriction enzyme ecor1 was measured in the presence of dna extracted from two lines of celo virus-induced hamster hepatoma cells and from control hamster cells. one hepatoma cell line (cilt-2), which did not produce the celo virus tumor (t) antigen, lacked sequences from about one-half the virus genome while the other hepatoma cell line (cehep), which did produce the celo vi ... | 1978 | 202577 |
some adenovirus dna is associated with the dna of permissive cells during productive or restricted growth. | we have investigated the association of viral dna with cell dna in chicken embryo kidney (cek) cells productively infected with chicken embryo lethal orphan (celo) virus and in human (hek) cells infected with mutants ts36 and ts125 of human adenovirus type 5 under permissive and restrictive conditions. cell and viral dna molecules were separated after celo virus infection of cek cells by alkaline sucrose gradient centrifugation, network formation, and cscl density gradient centrifugation, method ... | 1978 | 202728 |
[virus inactivation by hydrogen peroxide]. | the effect of h2o2 on adenovirus types 3 and 6, adenoassociated virus type 4, rhinoviruses 1a, 1b, and type 7, myxoviruses, influenza a and b, respiratory syncytial virus, strain long, and coronavirus strain 229e was studied in vitro, using different h2o2 concentration and timec of exposure. h2o2 in a 3 percent concentration inactivated all the viruses under study within 1--30 min. coronavirus and influenza viruses were found to be most sensitive. reoviruses, adenoviruses and adenoassociated vir ... | 1977 | 203115 |
the isolation of defective variants of simian virus 40 whose genomes contain sequences derived from adenovirus 2 dna. | a new set of hybrid viruses has been isolated whose closed circular genomes 5 to 6 kb in size, contain dna sequences derived in part from adenoviruses 2 and in part from sv40. the structure of these genomes is complex, but in the simplest case, analyses by restriction endonuclease digestion and hybridization indicate that the adenovirus 2 dna is present as a continuous block, of maximum size 2.8 kb. different hybrids contain sequences derived from different segments of the adenovirus 2 genome. | 1978 | 203654 |
immunization of chickens against adenovirus infection. | chickens were vaccinated with monovalent and polyvalent adenovirus vaccines using three different serotypes, types 1, 2, and 3. no cross-protection was elicited by the heterologous serotypes but satisfactory protection from lesions and the shedding of challenge virus was induced by the homologous serotypes in the monovalent and polyvalent vaccines. the virus neutralizing (vn) titers were occasionally lower where the polyvalent vaccines were used when compared to those from chickens given the mon ... | 1977 | 203922 |
the isolation of adenoviruses from goats affected with peste des petits ruminants in nigeria. | mucosal scrapings from the large intestine of two goats that had died from peste des petits ruminants (ppr) in separate outbreaks in nigeria were examined for viruses. a mixed viral infection of ppr virus (morbillivirus) and adenovirus was confirmed in both goats. the adenoviruses did not conform to any of the ovine and bovine serotypes recognised; the two isolates were considered different serotypes. it is concluded that, although the role of adenoviruses in the epizootiology of ppr in nigeria ... | 1977 | 203986 |
subclinical pneumonia associated with an experimental adenovirus infection in the domestic fowl and the effect of concurrent infectious laryngotracheitis virus. | a celo-type adenovirus (av) isolated from fowls with respiratory disease was inoculated experimentally into the tracheas of young birds. no symptoms referable to respiratory infection were evident. post mortem examination between days 2 and 5 after inoculation revealed pneumonia involving up to 30 per cent of the surface of the lungs. histologically, a focal to diffuse interstitial lymphocytic infiltration and bronchiolar degeneration were present. concurrent infections with a mild strain of inf ... | 1978 | 203988 |
physicochemical characterization and pathogenicity studies of two turkey adenovirus isolants. | two turkey adenoviruses were isolated from poults with respiratory disease, and their physicochemical properties were studied. the virus particles were unenveloped. contained dna genome, replicated within the nuclei of infected cells, and were icosahedral in shape. pathogenicity studies in poults indicated that north carolina kennedy isolant was a pathogen of relatively low virulence whereas the north carolina jackson isolant was nonpathogenic in commercial turkey poults. | 1977 | 204278 |
the canine contagious respiratory disease complex (kennel cough). | several infectious agents are involved in the kennel cough complex in dogs. they include canine parainfluenza virus (sv5), canine adenovirus 2, bordetella bronchiseptica, and possibly several mycoplasma species. the importance of each of these agents in the disease syndrome is discussed as well as possible prevention or treatment. | 1978 | 204455 |
necrotizing pancreatitis due to simian adenovirus type 31 in a rhesus monkey. | simian adenovirus type 31 was isolated from pancreatic tissue of an 8-year-old male rhesus monkey that died as the result of acute necrotizing pancreatitis. histologically, the pancreas showed wide-spread necrosis, extensive infiltration of polymorphonuclear leukocytes, and nuclear inclusions in pancreatic acinar cells. large numbers of adenovirus particles were demonstrable in the acinar cells by electron microscopy. this is the second case of adenovirus-associated pancreatitis we have found in ... | 1978 | 205187 |
development of immunocompetence in hamsters and the influence of dna oncogenic viruses. | | 1978 | 205440 |
characterization and sequence analysis of a recombination site in the hybrid virus ad2+nd. | | 1978 | 205651 |
the structure and expression of two defective adenovirus 2/simian virus 40 hybrids. | | 1978 | 205653 |
re: "the seattle virus watch. vii. observations of adenovirus infections". | | 1978 | 206135 |
simian adenoviral pneumonia. | in the past 6 years we have encountered 26 cases of fatal adenoviral pneumonia in six species of simian primates. o these, 22 animals were between 11 and 38 days old at the time of death, and pneumonia was the primary clinical disease. the spectrum of clinical disease varied from peracute fatal disease to inapparent disease with seroconversion. in one outbreak involving 4 infants housed together in an isolation unit, simian virus 11 was isolated from 3 of the infants and seroconversion occurred ... | 1978 | 206147 |
experimental infection of chickens with hemorrhagic enteritis virus. | chickens were experimentally infected with hemorrhagic enteritis virus, causing lesions similar to those observed in turkeys. lesions were induced by intraperitoneal and oral infection. virus particles with the morphology of adenovirus were demonstrated in the spleens of infected chickens. splenic extracts from infected chickens caused lesions of hemorrhagic enteritis in turkeys. recovery from the infection in chickens was followed by the production of antibodies to hev, demonstrated by agar-gel ... | 1978 | 206247 |
an adenovirus survey of poultry flocks during the growing and laying periods. | chicken adenoviruses were isolated from asymptomatic chickens on each of 7 farms tested; a majority of them induced cytopathology by the second serial passage. although adenoviruses were isolated from chickens ranging in age from 8 to 34 weeks, the highest isolation rate was from those 8 to 14 weeks. eight serotypes (1, 2, 4, 5, 6, 7, 8, and 9) were identified in a relatively small geographic area; serotypes 1, 4, 7, and 9 were isolated most frequently. multiple serotypes were found on 6 of 7 fa ... | 1978 | 206248 |
serologic and pathogenicity studies of avian adenovirus isolated from chickens with inclusion body hepatitis. | a virus initially thought to be inclusion body hepatitis virus (ibhv), tipton strain, was classified as an avian adenovirus (aav) and shown to be antigenically related to 2 serotypes of aav, 764 and yr36. the virus was antigenically unrelated to aav serotype tr-22, which included ibhv, tipton strain. inoculating specific-pathogen-free chickens with the virus produced hepatitis with basophilic and eosinophilic staining intranuclear inclusion bodies. | 1978 | 206251 |
a clinical evaluation of chickens inoculated with several avian adenovirus isolants. | clinical-chemistry values were determined in young specific-pathogen-free single-comb white leghorn chickens, both uninoculated and inoculated intra-abdominally at one day old with one of several avian adenovirus isolants. clinical values for plasma proteins and enzymes indicative of liver function were determined at 3, 7, 10, 14, and 21 days postinoculation. plasma glutamic oxalacetic transaminase and glutamic pyruvic transaminase activities were elevated in the virus-inoculated birds, along wi ... | 1978 | 206253 |
chemical- and virus-induced brain tumors. | experimental animal models resembling most human brain tumor types can be induced by exposure to oncogenic viruses or chemical carcinogens: astrocytomas and glioblastoma multiforme can be produced experimentally by intracerebral injection of oncornaviruses, whereas medulloblastomas, choroid plexus papillomas, and ependymomas can be induced by the papovaviruses. adenoviruses have been utilized to cause medulloepitheliomas, neuroblastomas, and retinoblastomas. all three groups of viruses can resul ... | 1977 | 206837 |
virological study of two commerical pig herds with respiratory disease. | | 1978 | 206933 |
[bell's palsy and virus infection (author's transl)]. | | 1978 | 207428 |
[isolation and detection of avian adenoviruses on cell cultures]. | it is important, from the hygienic and epizootological view-point, to detect the presence of various microbiological agents in birds. the authors present the results of the virological examination of poultry, avian adenoviruses being the main object of investigation. ninety-eight virus strains were isolated from chickens of different age categories and were included in the group of avian adenoviruses according to the form of cytopathic changes on the cell cultures of hen kidneys, according to th ... | 1978 | 208217 |
[antibodies against selected viruses and bedsonia in the body fluids of bovine abortions]. | | 1978 | 208219 |
comparative study of experimental inclusion body hepatitis of chickens caused by two serotypes of avian adenovirus. | twenty 1-day-old specific-pathogen-free chickens each were given an intraabdominal inoculation of either a type-8 avian adenovirus, [amg 5 (2a], or a type-5 avian adenovirus, inclusion body hepatitis virus (ibhv). the diseases produced were similar. high (60-100%) mortality and statistically significant depression of body weights occurred in both infections. there were necrotizing hepatitis and pancreatitis, lymphoid depletion in the spleen, bursa of fabricius and thymus, hydropericardium, nephr ... | 1978 | 208221 |
the fidelity of phosphorylation of the adenovirus dna-binding protein by an in vitro nuclear protein kinase from virus-infected cells. | | 1978 | 208253 |
serological studies in the elderly. | sera from 108 elderly patients in psychiatric and general hospitals were tested for antibodies to seven viruses. measles virus antibody levels were significantly higher in patients from the psychiatric hospital, regardless of diagnosis, than in those from other hospitals. demented patients, regardless of their hospital, had significantly higher levels of antibody to adenovirus than control patients. | 1978 | 208409 |
virus-specific markers and virus-like particles in cell lines of tumors produced by celo virus in syrian golden hamsters. | cell lines were established from 2 primary hepatocellular carcinomas (hc's) and 3 sarcomas produced in syrian golden hamsters inoculated as newborns with chicken embryo lethal orphan (celo) virus. cell lines from 2 sarcomas (cot, cmt) and 1 hc (cehep) produced celo virus-specific t-antigen. the antigen was not detected in cells of the third sarcoma line (rct) until they had undergone more than 34 passages in vitro. although 5-10% of cells in the second hc line (cilt/2) contained t-antigen during ... | 1978 | 209200 |
stimulation of antibodies to epstein-barr virus (ebv) in acute viral infections. | acute and convalescent sera from 77 patients with serologically confirmed influenza, measles and adenovirus infections and from 36 healthy controls were tested for the level of antibodies to epstein-barr (eb) virus. in the three groups of patients significantly higher titers of antibodies to eb viral capsid antigen (vca) were found as compared to the controls. in 19 patients twofold or higher rise in antibody titers between the first and second blood sample was demonstrated. it is suggested tha ... | 1978 | 209767 |
cell cycle-dependent multiplication of avian adenoviruses in chicken embryo fibroblasts. | propagation of celo virus employing confluent monolayers of chicken enbryo fibroblasts (cef) yielded virus titers one to two logs lower than those from confluent chicken kidney (ck) cells. an enhancement of virus production in cef as measured by plaque formation was obtainedby infectng cultures in the growing non confluent state. measurements of 3h-thymidine incorporation revealed a positive correlation between the dna synthesis of cef cultures at the time of inoculation and the amount of progen ... | 1978 | 209769 |
effect of avian adeno-associated virus on pathogenicity of tipton virus in chicks. | the avian adeno-associated virus (a-av) reduced the pathogenicity of an adenovirus infection in vivo. groups of chicks were infected with tipton virus alone or in combination with high or low doses of a-av. in both trials, the associated virus delayed and reduced chick mortality. this effect was dose-dependent and significant at the higher dose level. | 1978 | 209781 |
[attempts to demonstrate and identify avian adenoviruses by an immunofluorescence method]. | a specific conjugate of a hyperimmune serum, obtained from rabbits with the use of the reference phelps-celo strain, was employed in a direct immunofluorescence method to investigate more than 320 lamelles with cell cultures infected with 4 field celo virus strains and the reference phelps-celo strain. it is stated this method is specific and prompt for the early diagnosis and identification of adenoviruses (celo viruses). | 1978 | 210562 |
hamster embryo cells transformed by herpes simplex virus: reactions with adeno-associated satellite virus (aav) and its adenovirus helpers. | we have studied the reactions of hamster embryo cells transformed by ultraviolet-inactivated herpes simplex type 2 (333-8-9 t cells) to infections with adeno-associated satellite virus (aav) and its adenovirus helpers. resident hsv structural antigens were not detectable in early or late passage of 333-8-9 t cells. aav structural antigens were not detected in these cells unless the cells were coinfected with a helper adenovirus. in early passage 333-8-9 t cells were permissive to infections with ... | 1977 | 210924 |
antibodies in urine of chimpanzees with chronic adenoviral viruria. | many chimpanzees have naturally occurring chronic intermittent viruria with an adenovirus of a new type called pan 11. small amounts of neutralizing antibodies to pan 11 adenovirus were found in the urine of chimpanzees. urinary antibodies to adenovirus were mainly of the immunoglobulin g (igg) class with some iga antibodies also present. there was no neutralizing activity in urine against another adenovirus, pan 9, which has been isolated from lymph nodes, but not from urine, of chimpanzees; ho ... | 1978 | 211084 |
infection of mouse liver by human adenovirus type 5. | cba mice, inoculated intravenously with large doses of adenovirus type 5, showed raised levels of serum aspartate aminotransferase (saat; ec 2.6.i.i) and died within a few days from histologically demonstrable hepatic necrosis. after inoculation of i ld50, virus was rapidly taken up by the tissues where infectivity then declined greatly. organ titres then increased about 100-fold by 48 h p.i. but, in the liver, which showed intranuclear inclusion bodies, and by electron microscopy, scattered int ... | 1978 | 211182 |
synthesis and antiviral acticity of some phosphates of the broad-spectrum antiviral nucleoside, 1-beta-d-ribofuranosyl-1,2,4-triazole-3-carboxamide (ribavirin). | 1-beta-d-ribofuranosyl-1,2,4-triazole-3-carboxamide 5'-phosphate (2) was prepared and converted into the following derivatives: the 5'-phosphoramidate 3, the 5'-diphosphate 4, the 5'-triphosphate 5, and the cyclic 3',5'-phosphate 6. the cyclic 2',3'-phosphate 7 was prepared from the parent nucleoside, 1-beta-d-ribofuranosyl-1,2,4-triazole-3-carboxamide (1), and was opened to the 2'(3')-phosphate 8. these compounds were found to exhibit significant antiviral activity against several viruses in ce ... | 1978 | 211234 |
herpesvirus infection modifies adenovirus rna metabolism in adenovirus type 5-transformed cells. | the effect of herpes simplex virus (hsv) infection of mrna metabolism was examined in a system where the fate of specific rna sequence can be assayed. adenovirus type 5-transformed rat embryo cell line 107 synthesizes adenovirus-specific rna (ad-rna), which functions in the cytoplasm as mrna. we have utilized ad-rna as a model for mrna metabolism, and in a preliminiary study we characterized ad-rna in the nucleus and cytoplasm by hybridization to filter-bound adenovirus dna. the results indicate ... | 1978 | 211246 |
the use of polyethylene glycol in concentration and purification of several bovine viruses. | the polyethylene glycol (peg) precipitation method was used for the concentration and purification of eight bovine viruses. good results were obtained from four viruses, parainfluenza--3 virus, bovine enterovirus, bovine adenovirus, and bovine parvovirus. no satisfactory results of concentration were obtained from bovine reovirus, bovine viral diarrhea virus, and infectious bovine rhinotracheitis virus. the failure of concentration of the four viruses seems to be ascribed rather to the resuspend ... | 1978 | 211444 |
[genetic maps of tumor viruses (author's transl)]. | | 1978 | 211542 |
[replication, integration, transcription and gene products of tumor virus genome (author's transl)]. | | 1978 | 211543 |
dna viruses in urine after renal transplantation. | approximately 2 500 specimens from 96 renal transplant recipients were examined for virus particles. electron microscopy of negatively stained preparations showed that only 3 virus groups were present, namely polyomavirus, adenovirus and herpesvirus. no rna viruses or oncogenic rna viruses (retraviridae) were detected. over a 5-year period polyomavirus was excreted by 37,5% of patients. both herpesvirus and adenovirus were excreted by approximately 11% of the patients. although trace quantities ... | 1978 | 211648 |
avian adenoviruses: effect on egg production, shell quality, and feed consumption. | four avian adenovirus isolants (indiana c, dpi-2, ibh-2, and b-3)were examined for pathogenicity in laying birds. none affected shell quality, and only one (ibh-2) had even a minimal effect on egg production (faster decline). of three isolants tested (indiana c, dpi-2, and ibh-2), only ibh-2 caused feed intake to be reduced. no other clinical signs were observed during these experiments. egg transmission, virus excretion, and antibody production were found to mimic patterns reported for serotype ... | 1978 | 212004 |
electron microscopy in the diagnosis of infectious diarrhea. | | 1978 | 212395 |
conjunctivitis due to adenovirus type 19. | an outbreak of unusual conjunctivitis occurred in seattle in the summer of 1974. we found evidence of adenovirus type 19 (ad19) infection in 28 of 42 (67%) referred cases from whom specimens for virus isolation and/or serology were obtained. virus was isolated from conjunctiva, throats, and/or stools, often in week 2 of illness. ad19-related cases more frequently had severe ocular pathology, transient visual impairment, and active disease for longer than a week. secondary illnesses were more fre ... | 1978 | 212449 |
[functional organization of papova- and adenovirus dna]. | | 1978 | 212867 |
increases and perturbations in thymocytes forming spontaneous rosettes during viral and chemical oncogenesis in hamsters. | | 1978 | 213221 |
latent viruses and bell's palsy in children. | 4 children with unilateral facial palsy--bell's palsy (bp)--had serological evidence of primary infection with epstein-barr virus (ebv). concomitant infection with cytomegalovirus (cmv) was demonstrated in 1 child while in all 4 children a rise in antibody titers to an additional one or two viruses was demonstrated. the viruses involved were herpes simplex, cmv and adenovirus which are latent in humans. immunosuppression induced by ebv and steroid treatment may cause reactivation of these viruse ... | 1978 | 213283 |
persistent shedding of adenovirus in urine of chimpanzees. | a new adenovirus, designated pan 11, was isolated repeatedly from the urine of several chimpanzees for more than 1 year. one chimpanzee had chronic interstitial nephritis; the others were healthy. most chimpanzees tested had neutralizing antibodies to pan 11 virus in the serum; three people who worked with chimpanzees also acquired antibodies. transplantable rhabdomyosarcomas developed in hamsters inoculated as newborns with pan 11 virus. | 1978 | 213382 |
pharyngoconjunctival fever caused by adenovirus type 19. | a case of laboratory-acquired type 19 adenovirus infection is reported. the patient showed the classical triad of pharyngitis, acute follicular conjunctivitis and fever. adenovirus type 19 was isolated from the affected eye, and the infection was confirmed by demonstration of seroconversion to this virus. | 1978 | 213752 |
[various mechanisms of development of acute pneumonia in patients with respiratory viral diseases]. | | 1978 | 213897 |
differential in vitro growth properties of cells transformed by dna and rna tumor viruses. | | 1978 | 214320 |
egg-drop syndrome 76 in danish poultry. | after a more general mention of egg drop syndrome 76 (eds 76) an account is given of 3 cases of eds 76 in broiler parent flocks. in all cases the animals involved originated from ireland and were imported as day-olds, either directly from ireland or via sweden. serological examinations indicate that the infectious agent has not previously been present in danish hen flocks, but that it is presumably stationary in danish flocks of ducks. in 2 of the 3 cases of eds 76 animals from 2 different forei ... | 1978 | 214753 |
general features of persistent virus infections. | persistent virus infections are discussed from the virus point of view in terms of the bodily sites in which the infection persists. glands and body surfaces are thought to be significant because they give the virus protection at the topographical level from immune forces, and because they are appropriate sites for the shedding of virus to the exterior. germ cells are relevant sites because infection can thus be transmitted vertically from generation to generation in the host. the central nervou ... | 1978 | 214772 |
[pathogenesis of brain lesions in acute viral respiratory infections (review)]. | | 1978 | 214977 |
the effect of mixed infections induced by adenovirus type 5 and vaccinia or smallpox virus, on the ultrastructure of kb cells ii. observations of changes in the ultrastructure of kb cells during 6--11 days infection with adenovirus type 5 and vaccinia virus. | | 1978 | 215254 |
the effect of mixed infections induced by adenovirus type 5 and vaccinia or smallpox virus, on the ultrastructure of kb cells. iii. changes in the ultrastructure of kb cells within 6--11 days infection with adenovirus type 5 and smallpox virus. | | 1978 | 215255 |
fatal adenovirus type 7 pneumonia in an adult. | a case of fatal pneumonia caused by adenovirus type 7 in an adult is reported. this virus was isolated from the lung tissue, and typical inclusion bodies were found in histological sections. death due to adenovirus pneumonia in adults appears to be extremely rare. | 1978 | 215888 |
[activity of lactate dehydrogenase and its isofractions in experimental asymptomatic adenovirus infections]. | experimentally in 147 dog puppies an asymptomatic infection caused by adenovirus of human origin was produced and the process was caused to become manifest by administration of the same virus against the background of the effect of antilymphocyte serum. the activity of ldg in asymptomatic adenovirus infection was found to decrease in the cytoplasmic fraction of hepatocytes and to increase in the blood serum. an increase in the content of the "hepatic" complex of ldg in the blood serum and its de ... | 1978 | 216153 |
bovine adenoviruses. ii. electron microscopic studies and ultrastructural classification of strains akb and 37/67. | | 1978 | 216194 |
bovine respiratory viruses. | | 1978 | 216248 |
[acute hemorrhagic conjunctivitis (ahc). clinical aspects, epidemiology, virological and serological diagnosis of so-called apollo conjunctivitis]. | | 1978 | 217333 |
experimental intraamnionic exposure of bovine fetuses with subgroup 2, type 7 adenovirus. | three third trimester fetuses were exposed to a subgroup 2, type 7 adenovirus (adeno 7) by intraamnionic infection. the virus caused preterm delivery of two clinically ill calves and one stillbirth. the two premature calves died 12 and 72 hours after birth. an elevated serum neutralizing antibody titer (1:256) to adenovirus 7 was found in one principal calf at birth. adenovirus 7 was recovered from several tissues of the live calves and the spleen of the stillborn calf. fetuses exposed by intraa ... | 1978 | 217508 |
transformation of normal diploid cells by isolated metaphase chromosomes of virus-transformed or spontaneous tumor cells. | normal diploid human cells with a limited life-span in culture, as well as primary or secondary cell cultures of mouse or rat embryos, can be transformed in vitro (i.e. grow in soft-agar or low-serum medium) after a single exposure to metaphase chromosomes from sv40-transformed human or rat cells, ad5-transformed human cells and several spontaneous human or mouse tumor cells. chromosomes from normal diploid cells do not show any such transforming activity. as judged from the number of colonies f ... | 1978 | 217802 |
structure of the components of the adenovirus-simian virus 40 hybrid population ad2++hey and reciprocal molecular interactions. | | 1978 | 218019 |
adeno-associated virus autointerference. | | 1979 | 218354 |
structural relationship between the 100,000- and 17,000- molecular-weight t antigens of simian virus 40 (sv40) as deduced by comparison with the sv40-specific proteins coded by the nondefective adenovirus type 2-sv40 hybrid viruses. | the two-dimensional peptide maps of the methionine-containing tryptic peptides of the 100,000-molecular-weight (100k) and 17k t antigens of simian virus 40 (sv40) have been compared. the two proteins share nine methionine-containing tryptic peptides in common. the 17k t antigen has two peptides not found in the 100k t antigen, and the 100k t antigen has 14 unique peptides. the peptide maps of the 100 k and 17k t antigens were also compared with those of the sv40-specific proteins found in cells ... | 1979 | 219231 |
[effect of immunodepressants on latent viral infections in children with collagenosis]. | | 1979 | 219415 |
respiratory viruses in hospital patients on the witwatersrand. a 7-year study. | virological investigations were carried out on 4 151 patients with respiratory disease hospitalized between may 1966 and april 1972. the groups examined were black and white children and black miners. influenza viruses were more common among malnourished black children and tended to cause more severe disease. this was also true of adenovirus and herpesvirus hominis type 1 infections. adenoviruses appear to be secondary invaders, frequently after a measles or influenza attack. a generalized epide ... | 1979 | 219551 |
prevalence of antibodies to equine viruses in the netherlands. | the prevalence of antibodies to various viruses was investigated in a series of serum samples collected from horses in the netherlands between 1963 and 1966 and from 1972 onwards. neutralizing antibodies to equine rhinopneumonitis virus, equine arteritis virus and to equine rhinovirus types 1 and 2 were detected in respectively 76%, 14%, 66% and 59% of the equine serum samples tested. the observed incidence of serum samples positive to equine adenovirus in the complement fixation test was 39%. p ... | 1979 | 219560 |
adenovirus-associated virus polypeptides synthesized in cells coinfected with either adenovirus or herpesvirus. | | 1979 | 219599 |
[herpes simplex in acute viral respiratory diseases]. | herpes in main viral acute respiratory diseases (ard) in adults (influenza, parainfluenza, adenovirus and mixed infections) was studied by different laboratory methods of diagnosis. it was found that in 44.5% viral ard were accompanied by herpes in the clinically overt or latent form. herpes was detected with varying frequencies depending on the nosological forms of ard as well as on the nature of the infection: more frequently in monoinfections than in mixed infections. | 1978 | 219618 |
isolation and identification of a bovine adenovirus type 3 with an adenovirus-associated virus. | a bovine adenovirus with agglutinating activity was isolated from feedlot calves and classified as serotype 3. the agglutinating activity was shown to be the property of an adenovirus-associated virus (aav). the aav was isolated from the bovine adenovirus by isopycnic centrifugation in cscl; the aav had a density of 1.4 g/cm2. this aav is serologically related to bovine aav-tr-15, but is distinct from bovine parvovirus-1 and primate aav types 1 to 4, using counterimmunoelectrophoresis and hemagg ... | 1978 | 219733 |
[structure of inclusion bodies and electron microscopic virus detection in naturally occurring inclusion body hepatitis in chickens]. | electron microscopy was used to examine the liver of chickens with spontaneous inclusion body hepatitis. eosinophilic inclusion bodies only were established from two flocks, mainly amphophilic from one flock, and primarily basophilic from another two flocks. eosinophilic inclusion bodies were predominant in broiler chickens with dystrophic fatty degeneration of the liver, while basophile inclusion bodies were recorded primarily from parental or laying-hen chickens with reduced metabolic stress o ... | 1978 | 219796 |
experimental induction of hemorrhagic-aplastic anemia in chickens. i. etiology. | exposure to infectious bursal disease virus (ibdv) at 1 day old followed by inclusion body hepatitis virus (ibhv) inoculation at 36 days produced typical lesions of hemorrhagic-aplastic anemia syndrome (has). the lesions included severe anemia, widespread hemorrhages, and dermatitis. has could not be induced in the first 4 weeks of life in chickens inoculated at one day old with ibhv alone or in combination with ibdv. it was concluded that the immunosuppressive effects of ibdv failed to alter th ... | 1978 | 219831 |
experimental induction of hemorrhagic-aplastic anemia in chickens. ii. serum protein changes. | the serologic response of chickens to infectious bursal disease virus (ibdv) and inclusion body hepatitis virus (ibhv) was analyzed. inoculation at one day old with either ibdv or ibhv significantly (p less than 0.05) reduced levels of serum gamma-globulins at 4 weeks postinoculation. this response was not elicited by inoculation of ibdv together with ibhv. birds with experimentally induced or naturally occurring hemorrhagic anemia syndrome (has) had serum proteins quantitatively and qualitative ... | 1978 | 219832 |
hemagglutination-inhibition antibodies against an adenovirus (virus-127) in white pekin ducks in the united states. | | 1978 | 219838 |
[adenovirus induction of gene mutations in mammalian cells]. | | 1979 | 220000 |
studies of respiratory disease in random-source laboratory dogs: viral infections in unconditioned dogs. | a prospective study was conducted to identify the viruses causing respiratory diseases in unconditioned, random-source dogs. during the quarantine period, respiratory disease occurred in 86 of 167 (52%) dogs, and 34 (21%) died. most affected dogs had a distemper-like illness which required extensive and prolonged care. histopathologic studies confirmed the diagnosis of canine distemper in 10 of 12 (83%) fatal infections examined. sixty-seven of 91 (74%) dogs which arrived without canine distempe ... | 1979 | 220463 |
adeno-associated virus dna replication complexes in herpes simplex virus or adenovirus-infected cells. | a complex which is active in in vitro synthesis of adeno-associated virus (aav) dna was solubilized from vero cells that were co-infected with aav and either adenovirus (ad5) or a herpes simplex virus type 1 (hsv-1) as the helper virus. the complexes from the ad5 and hsv-1-infected cells sedimented at 23 s and 28 s, respectively. the optimal conditions for in vitro dna synthesis for the two types of complex using the endogenous aav template and the endogenous dna polymerase, differed with respec ... | 1979 | 221504 |
isolation of a virus indistinguishable from adenovirus 127 from chickens in the united states. | | 1978 | 221936 |
[myocarditis caused by viruses]. | | 1979 | 221962 |
comparison of cynomolgus and rhesus monkey kidney cells for recovery of viruses from clinical specimens. | in a study of virus recovery from clinical specimens, cynomolgus monkey kidney cells demonstrated sensitivity equivalent or slightly superior to rhesus kidney cells for siolation of myxo- and paramyxoviruses, adenoviruses, and enteroviruses. | 1979 | 222808 |
pharyngoconjunctival fever caused by adenovirus type 4: report of a swimming pool-related outbreak with recovery of virus from pool water. | during the summer of 1977, an outbreak of pharyngoconjunctival fever (pcf) occurred at a private recreational facility in georgia. a total of 72 cases of pcf was identified. adenovirus type 4 (av-4) was recovered from conjunctival or pharyngeal swab specimens from 20 of 26 persons in the group of cases tested. av-4 was also recovered, for the first time reported in the literature, from two concentrated samples of water obtained from the swimming pool at the facility on different dates. all perso ... | 1979 | 222852 |
[virusenteritis in childhood (author's transl)]. | about 20% of infantile enteritis are caused by bacterial infections. the most cases of non bacterial infantile enteritis are supposed to be viral infections. arguments for the existence of enterotropic viruses arised the first time in 1943. since the middle of the fifties, various kinds of enteroviruses are known to be causative agents of infantile gastroenteritis. the same is true occasionally for some types of adenovirus. in 1973 the norwalk-agent was discovered provocing enteritis mainly in a ... | 1979 | 222939 |
interferon induction by adenoviruses. | all human, simian, bovine and avian adenovirus types tested so far and the canine hepatitis virus induce interferon production in chick cells. this finding indicated this property to be characteristic for viruses belonging to the adenovirus group. trypsin treatment, which had no effect upon the infectivity, diminished or eliminated the interferon-inducing abilities of crude adenoviruses, and thus the need for a trypsin-sensitive protein in interferon induction was suggested. t antigen and interf ... | 1979 | 223139 |
some aspects of the role of viruses in cancer. | the cells of tumours induced by many oncogenic dna viruses, or cells transformed in vitro, contain virus-specific t and transplantation antigens; these have been described for sv40 virus, polyoma virus and adenoviruses. the investigation of viruses as causes of malignant disease in man has sought to establish whether tumour cells possess these virus-specific proteins; however, to date and with the limitations of present techniques, this enquiry has not demonstrated the above viruses as causal of ... | 1979 | 223141 |
adenovirus-associated virus-precipitating antibody as an early indicator of an adenovirus infection. | | 1979 | 223478 |
extrapulmonary manifestations of adenovirus type 7 pneumonia simulating reye syndrome and the possible role of an adenovirus toxin. | three children developed extensive extrapulmonary disease in the course of fatal adenovirus type 7 pneumonia. several clinical features, including the unexpected onset of coma, suggested the development of reye syndrome, but biochemical and histopathologic findings were inconsistent with this diagnosis. virologic and pathologic studies did not reveal evidence of extrapulmonary adenovirus infection, despite clinical involvement of the liver, skeletal muscle, and central nervous system. the detect ... | 1979 | 224159 |
mosaic adenovirus-sv40 rna specified by the non-defective hybrid virus ad2+nd4. | | 1979 | 224194 |
association of tumor induction by ultraviolet light-inactivated adenovirus 2-simian virus 40 recombinants with a specific segment of simian virus 40 dna. | the nondefective (nd) adenovirus 2 (ad2)-simian virus 40 (sv40) hybrid ad2+nd4, which contains the segment of the sv40 genome between map positions 0.11 and 0.59, induced tumors in syrian golden hamsters after inactivation by uv light. ad2 and the ad2+nd2 hybrid, which contains the segment of the sv40 genome between map positions 0.11 and 0.43, were not oncogenic after inactivation by uv light. these results showed that the incorporation of a specific segment of sv40 dna into the ad2 genome can ... | 1979 | 224235 |
comparative epidemiology of two rotavirus serotypes and other viral agents associated with pediatric gastroenteritis. | human rotavirus (hrv) type 1 or 2, adenovirus, or non-cultivatable 27 nm virus-like particles were demonstrated by electron microscopy and/or rotavirus elisa in fecal samples from 45.5% of 604 gastroenteritis inpatients, 25.0% of 200 gastroenteritis outpatients and 6.0% of 812 control subjects, all sampled at children's hospital national medical center. washington, dc. rotaviruses were the most common pathogens detected as 39% and 22% of gastroenteritis inpatients and outpatients, respectively, ... | 1979 | 224698 |
recurrent attack of rotavirus gastroenteritis after adenovirus-induced diarrhoea. | a 14-month-old baby boy suffered a second attack of rotavirus gastroenteritis within one month of the initial one. the second attack followed a diarrhoeal episode associated with adenovirus. gastrointestinal symptoms in the second attack were more severe than those of the first. the adenovirus-associated enteritis was mild compared with the illness in both episodes of rotavirus infection. | 1979 | 224825 |
sequence of inverted terminal repetitions from different adenoviruses: demonstration of conserved sequences and homology between sa7 termini and sv40 dna. | we have established the nucleotide sequence for the inverted terminal repetition of human adenovirus type 3, a subgroup b adenovirus. the repetition, which is 136 bp long, shows a high degree of homology with the known sequence for the inverted repetition of adenovirus type 5 (steenbergh et al., 1977) a subgroup c adenovirus. partial sequence information convering 120 bp of the inverted terminal repetitions of human serotype 12, a subgroup a member, and of simian adenovirus type 7 has also been ... | 1979 | 225041 |
adenovirus types 8 and 19 infection of rabbit corneal organ cultures. | adenovirus types 8 and 19 are responsible for a large number of cases of acute follicular conjunctivitis, mainly in the form of epidemic keratoconjunctivitis (ekc). this study successfully demonstrates the establishment of adenovirus infection in rabbit corneal organ cultures. normal rabbit corneas were maintained in culture without significant morphologic alterations for up to 7 weeks. adenovirus types 8 and 19 replication in rabbit corneas was demonstrated by viral growth curves and subpassage ... | 1979 | 225288 |
comparative sensitivity of a cultural test and the complement fixation test in the diagnosis of adenovirus ocular infection. | the sensitivity of human embryonic kidney (hek) cell culture and the complement fixation test (cft) in the diagnosis of adenovirus ocular infection has been compared. the optimum time for collection of specimens to obtain the best results by each test has been examined. sixty-one (53%) of 116 patients with moderate to severe follicular conjunctivitis, clinically indicative of adenovirus infection, had serological evidence of infection or had the virus isolated from ocular swabs. virus was isolat ... | 1979 | 226114 |
the indirect fluorescent antibody technique as a method for detecting antibodies in aborted fetuses. | in this investigation the indirect fluorescent antibody technique was used to titrate antibodies in bovine sera to parainfluenza 3, infectious bovine rhinotracheitis virus and bovine viral diarrhea virus. these results were compared to those determined on the same samples by hemagglutination inhibition for parainfluenza 3 virus and serum neutralization for bovine virus diarrhea and infectious bovine rhinotracheitis virus. the results of the serological methods agreed closely. the indirect fluore ... | 1979 | 226243 |
aerosol stability of bovine adenovirus type 3. | the wbr-1 strain of bovine adenovirus type 3 was suspended in eagle's medium or bovine nasal secretion and atomized into a rotating drum at temperatures of 6 degrees c or 32 degrees c and relative humidities of 30% or 90%. impinger samples of the aerosols were collected seven minutes, one, two and three hours postgeneration, and titrated for infectivity in embryonic bovine kidney cell cultures. under certain conditions of temperature and relative humidity, the virus was more stable in aerosols o ... | 1979 | 226247 |
evidence for an aetiological role for adenovirus type 7 in the mesenteric adenitis syndrome. | previous research has established the relationship between viral infection with adenovirus, influenza b virus and coxsackie b virus, and mesenteric adenitis. a prospective controlled survey of the incidence of viral infection in mesenteric adenitis was undertaken in children attending a children's hospital over a period of 13 months. eighteen patients, together with 18 controls who were matched for age, sex, and date of presentation, were studied. there were five cases of adenovirus type 7 infec ... | 1979 | 226850 |
further studies of antibody levels to herpes simplex virus, cytomegalovirus, measles virus, and adenovirus type 5 in burkitt's lymphoma patients. | sera collected from burkitt's lymphoma (bl) patients before and after tumor manifestation were tested for antibodies to herpes simplex virus (hsv), cytomegalovirus (cmv), measles virus (mv) and adenovirus type 5, using the immunofluorescent (if) techniques in all instances except for mv where complement fixation (cf) was used. it was found that none of these viruses showed higher antibody levels in bl patients than in controls, either before or after the appearance of the tumor. the patients cam ... | 1979 | 226855 |
egg drop syndrome, 1976 (eds'76). | a description is given of the new clinical condition in fowl now known as eds 76. this is characterised by the production of thin shelled, soft shelled and shell less eggs by apparently healthy birds. the effects on egg production are seen around 30 weeks of age and are seen either as an apparent fall in production or as a failure to obtain predicted production targets. haemagglutinating viruses have been isolated from these flocks and evidence from experimental and field investigations suggest ... | 1979 | 227136 |