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agglutinins to causative organism of contagious equine metritis 1977 in human serum. 197878032
coronavirus and gastroenteritis in foals. 197578197
[immunochemical investigations on the gene expression of horse serum carboxylesterase (author's transl)].immunochemical and enzymatic analyses of horse serum carboxylesterase were carried out with respect to the existence of a silent gene. sera with positive phenotypic expression of esterase, both heterozygotes and presumed homozygotes, were compared with:--sera with positive phenotypic expression but genotypically +/o;--sera with a negative phenotypic expression, i. e. genotypically o/o;--sera of natural +/o "hemi-zygotes": mules (donkey lacking the esterase);--positive sera heated at 60 degrees c ...197879331
[demonstration of the anti-thrombocyte effect of anti-human lymphocyte serum].a report is given how the antithrombocytic effect of 13 charges of human anti-lymphocyte globulin from the horse can be identified. the investigations were performed in mice and with the thrombocyte agglutination test. the test findings in mice correspond with those of the human compatibility control. therefore, the test in mice is recommended to be used for the laboratory examination of anti-human lymphocyte globulins.197879532
[the horse--a medium for sport therapy and social education in institutional work]. 197880005
antigenic homogeneity of equine adenoviruses. 197880214
gift-horse with nicotine-stained teeth. 197881422
site of initiation of the plasma cell reaction in the rabbit lymph node. ultrastructural evidence for two distinct antibody forming cell precursors.two times sublethal total body-x-irradiation with weekly local thymus irradiation established a t-cell deprived experimental model in rabbits. humoral immunity reactions in draining lymph nodes have been analyzed histologically and at the submicroscopical level after challenge with salmonella java vaccine, horse spleen ferritin, horse-gamma-globulin, a chemical sensitizer oxazolone (2 phenyl-4-ethoxymethylene-5-oxazolone) and after skin allografting respectively. the time sequence studies in the ...197881561
histophysiology of cellular immunity reactions in b-cell deprived rabbits. an x-irradiation model for delineation of an 'isolated t-cell system'.three times sublethal total body x-irradiation with thymus shielding--at 2 weeks' intervals--delineated a temporarily b-cell deprived animal model, only reconstituted with recently thymus-derived cells. the thymusdependent areas of peripheral lymphoid tissue-repleted with t-cells--are described. the cellular immune capacity of these animals with an "isolated t-cell system" was analyzed by means of skin allografting. histological and autoradiographic studies were performed in draining lymph nodes ...197881562
immunological studies on pancreatic phospholipase a2. antigenic characterization of the nh2-terminal region.rabbit antisera elicited against pure pig, horse, ox, and sheep pancreatic phospholipase a2 revealed considerable immunological differences when tested by double immunodiffusion and microcomplement fixation assays. snake venom phospholipases did not show any detectable cross-reactions with the pancreatic enzymes. microcomplement fixation also clearly demonstrated conformational differences between porcine phospholipase a2 and its zymogen. nh2 terminally modified analogs of porcine phospholipase ...197881837
organism of contagious equine metritis 1977 and human venereal disease. 197882103
analysis of a complex antigenic site on horse cytochrome c.of the antigenic determinants so far identified for cytochrome c, only one involves more than a single amino acid substitution between the immunogen and host proteins. both a threonine at position 89 and a glutamic acid at position 92 control one of the three antigenic sites identified in horse cytochrome c, as expressed in rabbits. three antibody subpopulations, all directed against this region of the molecule, were isolated from the serum of a single rabbit by adsorption on a series of insolub ...197882379
genetic polymorphism of the vitamin d binding protein and another post-albumin protein in horse serum.horizontal polyacrylamide gel electrophoreses, on 10% separation gel, of horse serum revealed polymorphism of the vitamin d binding protein (gc protein) and another post-albumin protein (pa). family data supported the hypothesis that gc and pa types were controlled by autosomal codominant alleles. for both gc and pa proteins, the homozygous types showed a single fraction while the heterozygous type had two fractions. pa types were found to be identical to the post-albumin types reported earlier ...197882413
k99 surface antigen of escherichia coli: antigenic characterization.k99 prepared by acid precipitation hemagglutinated guinea pig erythrocytes, whereas k99 prepared by chromatography on diethylaminoethyl-sephadex did not. k99 purified by either procedure hemagglutinated horse erythrocytes. k99 prepared by acid precipitation contained a second antigen not presnet in the k99 prepared by chromatography on diethylaminoethyl-sephadex. this antigen could be detected by immunoprecipitation with some, but not all, sera prepared against k99-positive escherichia coli stra ...197883300
broadly reacting precipitating and agglutinating antigen of leptospirae.a saprophytic leptospira biflexa strain of equine origin was found which cross-reacts with immune rabbit antisera to 14 pathogenic leptospira interrogans serotypes. sera from goats experimentally inoculated with the saprophyte showed multiple low-level cross-agglutination reactions against a battery of live l. interrogans serotypes. sonically treated and saline-extracted suspensions of the l. biflexa strain and serotypes canicola, icterohaemorrhagiae, and pomona yielded a common precipitating pr ...197883327
equine markers genes. polymorphism for group-specific component (gc).polymorphism of equine gc protein was demonstrated by immunofixation electrophoresis with a goat anti-human gc antibody. three different phenotypes, f, fs and s, were found. family data supported the genetic theory of two autosomal codominant alleles, gcf and gcs. both alleles occurred in standardbred, thoroughbred and arabian horses and in shetland ponies. a frequency of 0.23 for gcs in the american standardbred horse indicates the system should be useful for problems of identification and pare ...197884540
immunological release of histamine and slow-reacting substance in domestic fowl.immunological release of histamine from the whole blood of the sensitized chickens was demonstrated. compound 48/80 (a potent histamine releaser) released histamine from isolated chicken lung. the sensitizing antigens (bovine albumin or horse plasma) did not release histamine from the lung. bovine albumin and horse plasma released slow-reacting substance of anaphylaxis only from the lungs of adult domestic fowl and not from ileum or lungs of immature chickens.197884701
oxidation of steroids with the 20beta-hydroxy-21-oxo side chain to 20beta-hydroxy-21-oic acids by horse liver aldehyde dehydrogenases. 197884891
[enhancement phenomenon in mice with a heterotopic heart transplant].a possibility of enhancement induction with the aid of a preparation of lymphocyte membranes of the spleen of donor specificity in its combination with antimouse horse globulin was studied on mice with heterotopic graft of the heart. as shown, in recipients with prolongation of the graft electrical activity lymphocytes retained their reaction to donor antigens, whereas the blood serum produced an enhancement effect in its administration to syngeneic recipients.197885397
clostridial infection in a horse. 197985621
tissue distribution of human alpha1-microglobulin.human alpha(1)-microglobulin was isolated from the urine of patients with tubular proteinuria, and its molecular weight was established by sodium dodecyl sulfate-polyacrylamide gel electrophoresis at 33,000 daltons. the carbohydrate content was 21.7%. anti-alpha(1)-microglobulin serum was prepared and observed to react monospecifically in gel diffusion to purified alpha(1)-microglobulin, as well as to normal human serum and urine. sera from the domestic chicken, mouse, rat, rabbit, dog, calf, co ...197985635
a possible role for cyclic gmp in mediating the effect of luteinizing hormone releasing hormone on gonadotropin release in dispersed pituitary cells of the female rat.in continuing studies on cyclic nucleotide involvement in the regulation of gonadotropin release, we have measured the cyclic nucleotide content and rate of lh and fsh release during stimulation by lhrh of dispersed overnight cultured cells from the pituitaries of adult female rats. the minimal effective concentration of lhrh was 0.1 nm and half maximal stimulation of gonadotropin release was observed in the presence of 1.0 nm lhrh. significant release of both lh and fsh was detectable after onl ...197885642
the induction of cell-mediated immunity and tolerance with protein antigens coupled to syngeneic lymphoid cells.a mouse model of cell-mediated immunity (cmi) and tolerance to protein antigens horse gamma globulin (hogg) and cytochrome (cyt c) was investigated. a reliable cmi response as measured in vivo by ear swelling or by an in vitro t-cell proliferation assay could be induced by one of two methods: (a) sensitization by antigen-complete freund's adjuvant in the base of the tail, or (b) sensitization by s.c. injection of antigen coupled to syngeneic lymphoid cells. the in vivo response exhibited charact ...197985683
serological response of patients with non-gonococcal urethritis to causative organism of contagious equine metritis 1977.the presence of allugtinins to the causative organism of contagious equine metritis (c.e.m.) in human serum has been confirmed. agglutinins were found in the serum of 84 (37.6%) of 223 patients with non-gonococcal urethritis (n.g.u.), and in 12.5% of these patients there was a four-fold or greater rise in titre during the course of their illness. there was no evidence that these agglutinins were the result of infection by chlamydiae or ureaplasmas. certain patients with these agglutinins seemed ...197985938
studies on methods to remove antierythrocyte antibodies from horse anti-human thymocyte globulin. 197986217
evidence for the presence of an antitumor factor in serum of normal animals.we have previously reported finding a factor with antitumor activity (tnf, tumor necrosis factor) in extracts of serum from normal mice. the possibility that tnf exists in the blood of normal animals of other species was explored. horse, mouse, dog, human, sheep, calf, rat and shark serums were fractionated with (nh4)2so4 and filtered through s-200 sephacryl gel. proteins of molecular weight 90,000 to 180,000 were pooled, concentrated and dialyzed. tnf, determined by l-cell assay in vitro and me ...197986384
the in vitro induction of t cells which mediate delayed-type hypersensitivity toward horse red blood cells. 197986387
[admixtures present in antitoxic horse sera and pepsin preparations].antitoxic therapeutic sera produced by the method "diaferm-3" (devised at the institute of epidemiology and microbiology of the ussr academy of medical sciences) are contaminated in the process of production with group-specific substances and extraneous enzymes contained in crude preparations of swine pepsin. these ballast substances have a negative influence on the process of purification and the stability of antitoxin during the storage of the sera and constitute one of the reasons of their hi ...197987071
in situ identification of mononuclear cells infiltrating cutaneous carcinoma: an immuno-histochemical study.the present study was undertaken in order to investigate the exact nature of the cells surrounding cutaneous tumours. formalin-fixed, paraffin-embedded sections were tested with a horse antihuman t lymphocyte serum and with igg, iga and igm rabbit antihuman serum. all the sections were respectively treated with rabbit anti-horse or swine antirabbit peroxidase-labelled serum. the advantages offered by the immunoperoxidase technique are briefly discussed. t cells are in overwhelming proportion in ...197987078
synthesis of long complementary dna in the endogenous reaction by equine infectious anemia virus.in the endogenous reverse transcriptase reaction, equine infectious anemia virus is able to synthesize complementary dna (cdna) of 8,000 nucleotides in high yield. after 2 h in 50 mum dntp, about 2.8 mug of cdna per mg of protein is produced, almost 30% of which is long cdna. the system thus compares favorably with the other two well-characterized endogenous reaction systems, moloney murine leukemia virus and avian sarcoma virus. elongation rates of 100 to 150 nucleotides per min have been obser ...197987522
[immunochemical study of the leukocyte myeloperoxidases from various sources].the antigenic difference between myeloperoxidases of human, rabbit, guinea pig, horse, dog, sheep and mouse leucocytes and horse radish peroxidase was investigated. by counterimmunoelectrophoresis with antiserum specific for human and mouse myeloperoxidase and horse radish peroxidase, the enzyme catalysing peroxidase reaction in leucocytes from the above sources was shown to possess species specificity and different antigenic composition.197988108
[use of gravohormon for shortening the service peroid and its effect on gonadotropic hormone incretion and on protein-bound iodine in the blood of cows]. 197888793
the production and control of anti--venous sera.this paper describes the species of venomous snakes found in costa rica as well as anti-venom sera prepared by the instituto clodomiro picado: polyvalent sera for use in human or veterinary medicine, and anti-micrurus and anti-lachesis monovalent sera. these sera are prepared in horses, purified with ammonium sulphate, then concentrated and delivered either in liquid or freeze-dried form. controls are in accordance with nih recommendations. for cases of hypersensitivity to horse serum, a polyval ...197889053
immunochemical and oligonucleotide fingerprint analyses of venezuelan equine encephalomyelitis complex viruses.rna oligonucleotide fingerprint analyses indicate that the genome rna obtained from trinidad donkey (trd) venezuelan equine encephalomyelitis (vee) virus serotype i a, its vaccine strain derivative tc-83, and the vee i b virus isolate ptf-39, have almost identical patterns of characteristic ribonuclease t1 resistant oligonucleotides. the tc-83 strain and the i b isolate can, on the basis of these analyses, be considered as variants of the trd virus and categorized as i ab serotypes. comparisons ...197990115
identification and characterisation of the major antiproteases in equine serum and an investigation of their role in the onset of chronic obstructive pulmonary disease (copd).three major antiprotease components in equine serum were identified and characterised. these were the acidic prealbumin pr, the homologue of human alpha-1 antitrypsin and 2 protease binding proteins, the acidic prealbumin xc and alpha-2 macroglobulin, both capable of inhibiting the proteolytic activity of trypsin, but with only limited inhibitory effect on its esterolytic activity. the possible role of these serum antiproteases in the onset of chronic obstructive pulmonary disease (copd), analog ...197990612
inhibition of specific immune responses by feeding protein antigens. iv. evidence for tolerance and specific active suppression of cell-mediated immune responses to ovalbumin.we studied the effect of a single intragastric administration of ovalbumin (ova) on the subsequent development of ova-specific cell-mediated immune (cmi) responses in bdf1 mice. in animals fed ova 7 days before subcutaneous sensitization with ova-cfa, we observed a concomitant dose-dependent decrease in both the humoral and cmi responses specific for ova. the cmi tolerance was found to be antigen-specific when assayed in vivo by ear swelling or in vitro by an antigen-induced t cell proliferation ...197990707
fractionation of rabbit anti-horse cytochrome c--i. specificity of the isolated fractions. 197991093
purification of the subunit clq from the first component of equine complement.initial separation and concentration of clq from fresh, normal equine serum was accomplished by precipitation in 0.02 m acetate buffer, ph 5.5, at 4 degrees for 24 h. the re-dissolved precipitate was clarified by centrifugation at 80,000 g for 1 h and then dialysed against tris-hcl buffer (0.05 m, ph 8.0) containing 10-3 m edta. the clarified dialysate remained biologically active at 5 degrees for at least 4 weeks. biological activity of equine clq was determined by assay of its ability to agglu ...197991570
topographic antigenic determinants on cytochrome c. immunoadsorbent separation of the rabbit antibody populations directed against horse cytochrome.seven populations of site-specific antibodies were isolated from each of three sera of rabbits immunized against glutaraldehyde-polymerized horse cytochrome c. the antibodies were separated using an immunoadsorption scheme which employed the following cytochromes c: horse, beef, guanaco, rabbit, mouse testicular, pigeon, and the cyanogen-bromide cleaved fragment of the rabbit protein containing residues 1 to 65. the monovalent, antigen-binding fragments of the antibodies (fab') gave 1:1 stoichio ...197991614
the effect of training and detraining on several enzymes in horse skeletal muscle.training and detraining had little effect on the activity of glycogen synthase, hexokinase, glycerol 3-phosphate dehydrogenase or total protein. the activity of 3-hydroxyacyl-coa dehydrogenase increased markedly during training. after 5 weeks of detraining, the activity of 3-hydroxyacyl-coa dehydrogenase was returning to pre-training values, whilst by 10-week detraining, the levels were increasing again.197992293
continuous proliferation of murine antigen-specific helper t lymphocytes in culture.murine helper t cells activated to sheep or horse erythrocyte antigens in vivo have been established as continuous cell lines in culture. t cells require the presence of a t-cell growth factor (tcgf) for continuous proliferation. tcgf purified from murine, rat, or human sources all stimulate murine t-cell growth. the t-cell mitogens concanavalin a and phytohemagglutinin do not stimulate cell proliferation in continuous t-cell lines. all cells that grow in the presence of tcgf express thy-1 antig ...197992524
relationship between receptor occupancy and stimulation of adenosin-3',5'-monophosphate (camp) and progesterone production in isolated rat granulosa cells. 197992614
characterization of various horse thyroid forms of cyclic-nucleotide phosphodiesterase [proceedings]. 197992956
equine igg and igg(t) antibodies: dependence of precipitability on both antigen and antibody structure. 197993077
antigenic determinants of horse cytochrome c for lymphocyte transformation: identification of an immunodominant peptide. 197993078
myxobacterial hemagglutinin: a development-specific lectin of myxococcus xanthus.fruiting body formation in the bacterium myxococcus xanthus consists of a temporal sequence of cellular aggregation and sporulation. during the period of cellular aggregation, a major new development-specific protein that has lectin-like activity is synthesized. this protein, called myxobacterial hemagglutinin (mbha), was able to agglutinate sheep or guinea pig erythrocytes but not horse, ox, chicken, or human erythrocytes. mbha was undetectable in extracts of vegetative cells, cells starved in ...197993278
arthropod-borne encephalitides in the americas.the arthropod-borne encephalitides are an important cause of equine and human morbidity in the americas. between 1975 and 1978, 6970 human cases of arboviral encephalitis were reported in the united states of america; however, this represents only a fraction of the true incidence. st louis encephalitis (4824 cases), california encephalitis (1035 cases), and western equine encephalitis (wee, 947 cases) accounted for 98.5% of all reported infections. approximately 1000-4000 cases of equine encepha ...197993518
neutralizing antibody responses of humans and mice to vaccination with venezuelan encephalitis (tc-83) virus.laboratory workers were vaccinated with venezuelan encephalitis virus, strain tc-83. after 2 to 3 years, they were bled, and their sera were tested for neutralizing antibody to all known venezuelan encephalitis subtypes and varieties. the results indicated higher titers to epizootic than to enzootic venezuelan encephalitis viruses and suggested that individuals vaccinated with tc-83 do not produce significant neutralizing antibody to heterologous subtypes. mice vaccinated, bled, and tested in a ...197993607
[inhibition of neutral leukocyte proteases by horse protease inhibitors]. 197993783
[complement fixation reaction studies in rhinopneumonitis of horses].it was established that the complement binding reaction (cbr) is a suitable and very fast method for horse rhino-pneumonitis diagnostics. cell cultural virus produced in cell cultures of pig kidneys was used as antigen. the antigen lots tested have no anticomplementary properties. highest complement binding activity was evident in the non-diluted antigen, which discovered specific antibodies in immune serums. the cbr specificity was tested by the aid of homologous and heterologous serums and ant ...197994480
an in vitro culture system for crayfish organs.organs of crayfishes--mainly integument of astacus leptodactylus--have been kept in an in vitro culture of several days. the medium consists of 2 parts of van harreveld saline and one part of horse serum, supplemented with antibiotics for long term cultures. this medium is very similar to the astacus hemolymph in its ionic content, the ph, the osmolarity, the protein concentration and the cholesterol content. the glucose concentration is somewhat higher and there are differences in the nitrogen ...197994722
genetic polymorphism and close linkage of two alpha 1-protease inhibitors in horse serum.two-dimensional electrophoretic analysis of horse serum proteins was done by a first-dimension separation in agarose gel (ph 5.4) followed by a second-dimension separation in horizontal polyacrylamide gel (ph 9.0). this method resulted in improved and reproducible separation of many alpha-globulins. two groups of alpha 1-globulins, designated pi1 and pi2, were found to be protease inhibitors. preliminary studies indicated that pi1 and pi2 proteins differed from each other in molecular weight and ...197994978
immunology of a persistent retrovirus infection--equine infectious anemia. 197995154
stilboestrol (diethylstilbestrol) and the risk of ovarian cancer.a follow-up survey of 908 women who had received 'premarin' (conjugated equine oestrogen) for menopausal symptoms revealed 8 cases of ovarian cancer. this risk was 2 to 3 times greater than expected. the risk increased with the strength of premarin tablet usually taken, but not with the duration of use or total dose ingested. the excess risk of ovarian cancer in this group occurred primarily among 21 women who had also used stilboestrol (diethylstilbestrol). the results of this small trial are c ...197795735
[oesophageal diverticulum in a pony (author's transl)].a case of oesophageal diverticulum in a pony is reported. the diagnosis was established by clinical and x-ray examination (following administration of a contrast agent) and verified by post-mortem studies. the cause and pathogenesis are discussed.197896547
[occurence of an outbreak of horse dermatophytosis caused by the fungus trichophyton equinum].there is a description of equine dermatophytosis enzootic, caused by the microscopic fungus trichophyton equinum. the disease affected 32 horses, mostly young, all in the same herd (74.4%). the diseased horses were successfully treated with the preparation fenoform forte, applied superficially at the concentration of 0.5% of the active substance. the authors made an attempt to determine the criteria for clinical differentiation of fully developed trichophytosis and microsporosis of horses. trich ...197896566
[nonspecificity of antiviral protein action].the authors studied the antiviral activity of the informative rna of antiviral protein (m-rna avp) isolated from the cells following superinduction of interferon in them for the purpose of ascertaining the action specificity of the product of their translation--avp. following the administration of m-ran avp a marked (from 1 to 5 lg pfu/mil) reduction of the infectious titres was observed in the homologous and heterologous cells. rna preparations from control (noninduced) cells possessed a weak ( ...197896890
[cochliatoxum periachtum gassovsky, 1919, entodinimorphic ciliate of the horse digestive tract].the topography of cochliatoxum periachtum is studied. the cuticle is very thick. the digestive, nuclear and excretory systems are located in the ectoplasm, they are not surrounded by the mesoplasm. the endoplasm is very large, it contains vegetable inclusions. by the features of its topography, this species is similar to some species belonging to the family ophryoscolescidae and, especially, to eudiplodinium giganteum.197796938
isolation of the l-phase variant from toxigenic corynebacterium diphtheriae c7(beta).the l-phase variant was isolated from lysogenic strain c7(beta) of corynebacterium diphtheriae by the penicillin disk tecnnique on an agar medium containing 3.7% brain heart infusion, 3% nacl, 1.25% grycine, 1% noble agar, and 10% horse serum. the l-phase formed a "fried egg" colony; it was resistant to antibiotics that inhibit biosynthesis of bacterial cell walls but was susceptible to antibiotics that act on the protein-synthesizing system. after several transfers of the l-phase initially isol ...197897222
mr. pechsniff's horse? (psychodynamics in compulsive drug use). 197797538
discriminatory effect of anti-pr-beta-hcg-tt antibodies on the neutralization of the biological activity of placental and pituitary gonadotropins.in 2 test systems, serum from monkeys and human subjects immunized with an anti-human chorionic gonadotropin (hcg) vaccine, pr-beta-hcg-tt, were analyzed for their capacities to neutralize hcg/luteinizing hormone (lh)-induced biological effects. hcg-induced ovulation was completely blocked by the monkey antiserum in mice, but the same amount of antiserum, and even 2-fold greater concentrations, did not reduce the number of ovulating animals when primed with ovine lh. competency of both the imm ...197898287
[immunodiffusion serologic study of equine infectious anemia in the province of buenos aires, argentina].twenty seven per cent of 238 serum samples obtained from horses with clinical diagnosis were positive for the immunodifusion test, while 17% of the 452 sera obtained from asintomatic horses were positive. twenty one per cent of the 870 sera studied were positive.197898810
[the value of the immunodiffusion test in the diagnosis of animal histoplasmosis].a serological study which involved the agar gel immunodiffusion test of 11316 animal serum samples (porcine, bovine, equine and ovine cattles) was made in the havana province in an attempt to detect precipitation bands for histoplasma capsulatum. 135 porcine serum samples and 4 bovine serum samples were positive.197798818
influence of promazine on the venous haematocrit and plasma protein concentration in the horse. 197898935
the causative organism of contagious equine metritis 1977: proposal for a new species to be known as haemophilus equigenitalis.the aetiological agent of contagious equine metritis (cem) has been investigated bacteriologically in a wide range of cultural and conventional biochemical tests, in the eletron microscope, for dna base composition (36.1 per cent gc), for susceptibility to various antimicrobial agents and antigenically by means of tube and slide agglutination tests. the organism is a fastidious, gramnegative, non acid-fast coccobacillus which in biochemical tests is very unreactive. in conventional tests, only t ...197899302
equine radiology: the esophagus. 197899648
[indirect hemagglutination test at the ultrastructural level].a study on ultra-thin sections was made of the preparations of agglutinate produced during the reaction of the immunoglobulin erythrocytic diagnostic agent with dry corpuscular rickettsia prowazeki antigen, fluoresceine isothiocyanate labeled, and also srbc used for the preparation of the diagnostic agent after formalinization, tannin treatment, sensitization with hyperimmune horse serum immunoglobulins and lyophilization, respectively. formalin and tannin treatment of erythrocytes failed to be ...197899928
electron microscopy of cellular immunity reactions in b-cell deprived rabbits. thymus derived antigen reactive cells, their micro-environment and progeny in the lymph node.three times sublethal total body x-irradiation with thymus shielding--at 14 days' intervals--established an 'isolated t-cell system'. cellular immunity reactions in draining lymph nodes of rabbits have been analyzed at the ultrastructural level after challenge with horse spleen ferritin, the chemical sensitizer, 2-phenyl-4-ethoxymethylene-5-oxazolone and after skin allografting. a basic pattern of interdigitating cells (idc) is described as a specific constituent of the thymus-dependent areas of ...1978100957
[roentgenologic findings in diseases of skeletal parts of the spine, intervertebral disks and the spinal meninges in dogs, cats and horses]. 1978100988
in-vitro antimicrobial susceptibility of neisseria gonorrhoeae in new zealand.four hundred and forty-two isolates of neisseria gonorrhoeae were tested by an agar dilution method for their susceptibility to penicillin, ampicillin, tetracycline, cephaloridine, and spectinomycin. of these isolates, 295 were tested for their susceptibility to sulphamethoxazole and to trimethoprim by the same method, using oxoid diagnostic sensitivity test agar plus 7.5% laked horse blood instead of proteose no. 3 agar plus 1% isovitalex and 1% haemoglobin. one hundred (22.6%) of the isolates ...1978101276
taurine and other free amino acids in milk of man and other mammals.taurine and other free amino acids have been determined in human milk of a number of other species. taurine is the most abundant free amino acid in the milk of the gerbil, mouse, cat, dog and rhesus monkey. taurine is the second most abundant amino acid in the milk of the rat, baboon, chimpanzee, sheep, java monkey and man. taurine is not a major constituent in the milk of the guinea pig, rabbit, cow and horse. the milk of each species has a characteristic free amino acid pattern which may be an ...1978102507
surgical correction of esophageal diverticulum in a horse. 1978102627
a stimulatory effect of the fluid from preimplantation rabbit blastocysts upon luteinization of monkey granulosa cell cultures.blastocyst fluid was aspirated from day 6 1/2--7 rabbit blastocysts and was added to cultures of granulosa cells obtained from preovulatory follicles of untreated rhesus monkeys or from follicles of monkeys or from follicles of monkeys treated with pmsg. the stimulation of progesterone secretion was measured and equated with that produced by hcg. the hcg-like activity was also measured in a radioreceptor assay using 125i-labelled hcg and porcine granulosa cells. in 8 out of 10 experiments with c ...1978102788
efficacy and toxicity of furazolidone in veterinary medicine. (a review). 1978103274
[diagnosis of infectious anemia in horses using the coggins test].coggins' immune diffusion test was modified, and was applied as a screening one in the study of the epizootic status. the positive reactions were characterized by the production of a precipitation line between the antigen and the respective serum that was tested. the appearance of such a line was associated with that formed with the use of the positive control serum, pointing to a reaction of identity. with the weakly positive reactions the ends of the precipitin lines, formed with the use of th ...1978103281
k-1 antigen of escherichia coli: epidemiology and serum sensitivity of pathogenic strains.k-1 escherichia coli are far more frequent in neonatal sepsis (36% of e. coli sepsis) and meningitis (80% of e. coli meningitis) than would be expected by the frequency of k-1 e. coli colonization in neonates (11 to 25%). there is no apparent parallel in cases of sepsis in adults. to study further this apparent age-related difference in virulence, e. coli k-1 clinical isolates were tested for their sensitivity to sera. strains isolated from cases of neonatal meningitis were more sensitive to ser ...1978103825
hemolysin of myxococcus fulvus nk 35 i. production and isolation.myxococcus fulvus nk 35 has been shown to produce a soluble hemolysin which lysed rabbit, human, horse, and sheep erythrocytes. a medium (varghese's medium) was devised in which a maximum of hemolysin was produced in 6 days at 28 degrees c under static conditions. the lysin was precipitated by complete saturation of the culture filtrate with ammonium sulphate, followed by dialysis against saline. other enzyme systems were destroyed by heating at 100 degrees c. further purification was achieved b ...1978104473
[mineral metabolism of the horse. ii. seasonal influence on the serum concentration of calcium, phosphorus, magnesium, alkaline phosphatase and 24-hydroxyvitamin d3 in young horses]. 1978104502
a serologic survey of mule deer and elk in utah.sera from mule deer (odocoileus hemionus) and elk (cervus canadensis) in central and northern utah were tested for the prevalence of antibodies to 11 diseases communicable to man or domestic livestock. antibodies to francisella tularensis (at 1:20) were found in 47 of 88 (53.4%) elk and 1 of 89 (1.1%) deer. a screening slide agglutination test for titers to brucella (at 1:20) showed two reactors in elk but none in deer sera. no positive antibody titers were obtained in tests for anaplasmosis, co ...1978105153
the preparation and immunosuppressive properties of equine antihuman thymocyte membrane immunoglobulin g.human thymocytes separated by a ficoll gradient produced a cell population that was 99% pure thymocytes and free of platelets, leukocytes, and epithelial cells. these cells, disrupted by a nitrogen bomb, produced a membrane-ribosome antigen fraction confirmed by enzyme analysis. equine antithymocyte membrane-immunoglobulin g (atm-igc) prepared against this antigen in four of five horses contained immunosuppressive properties capable of prolonging monkey skin allograft survival longer than 21 day ...1979105416
[isolation of treponemas from the colon of pigs with clinical dysentery].optimal culture conditions in artificial nutritive media were determined for a defined avirulent strain of treponema hyodysenteriae and for four field strains of treponemas in pigs with clinical dysentery. the treponemas were isolated with the use of milliporous filters with pores of 0.3 micrometer in diameter, which were located on the surface of blood agar. no significant difference in the influence of equine, bovine or sheep blood on the growth of treponemas was determined. the commercial amo ...1979105448
brucella cultures typed by the who brucellosis centre at the commonwealth serum laboratories, melbourne.results of the typing of brucella cultures received at the who brucellosis centre, csl, melbourne, from 1968-1976 are presented. the distribution of the biotypes of cultures recovered throughout australia is shown on a host and state basis and atypical cultures are discussed. cultures identified from australia were br. abortus, biotypes 1, 2 and 4 and strain 19; br. suis, biotype 1 and br. ovis. br. melitensis biotypes 1, 2 and 3 were recorded only as exotic human infections from the mediterrane ...1978105700
thermostable antigens from the bone marrow of several animal species.studies on bone marrow extracts from ten animal species have revealed the presence of thermostable antigens. similar antigens were found in other organs as shown by immunodiffusion and cross-reactivity was demonstrated between the thermostable proteins from horse and dog and between cow and sheep proteins. using an immunoenzymatic reaction with glucose oxidase as the marker, the thermostable antigens were localized in the blood and bone marrow polymorphonuclear leukocytes and the myeloid cell li ...1978105786
pyrimidine metabolism in lymphocytes and erythrocytes of man, horse and cattle. 1979105941
[intensification of antibacterial and antiviral nonsusceptibility and of the immune response with an officinal rna preparation].sodium nucleinate increased essentially the insusceptibility of mice to pathogenic escherichia, strain o26, pr. vulgaris, ps. aeruginosa, ser. marcescens, and produced a total stimulating effect on the nonspecific bacterial resistance; analogous stimulating activity was found in the homologous low polymeric rna from the liver. sodium nucleinate intensified the insusceptibility of the animals to the tick-born encephalitis and encephalomyelitis viruses, and increased the antibody-forming cells cou ...1979106911
the relationship of brucella abortus titers to equine fistulous withers in ethiopia. 1979107647
pregnant mare serum gonadotropin. purification and physicochemical, biological, and immunological characterization. 1979108273
demonstration and characterization of specific binding sites for factor viii/von willebrand factor on human platelets.the presence of specific factor viii/von willebrand factor (fviii/vwf) binding sites on human platelets has been demonstrated by using 125i-fviii/vwf and washed human platelets. binding is ristocetin-dependent and increases in proportion to the concentration of ristocetin from 0.2 to 1 mg/ml. binding of 125i-fviii/vwf to platelets can be competitively inhibited by unlabeled human or bovine fviii/vwf, but not by human thrombin, fibrinogen, alpha 2-macroglobulin, equine collagen, or a lectin of ri ...1979108291
[new species of microsporidians (microsporidia, nosematidae) from horsefly larvae in the ukraine].a new species of microsporidians, stempellia lairdi sp. n., was found in larvae of tabanus autumnalis l. from ukraine. it affects the muscular tissue and haemolymph of horse fly larvae. spores of the species are oval, egg-shaped, 1.8--7.6 x 1.2--3.8 mu in size. the species is pathogenic and causes the mortality of infected larvae.1979108652
preparative cell electrophoresis with d2o as a stabilizing agent.the method of ascending preparative cell electrophoresis in a nonstabilized vertical column can be greatly improved by layering the cells on a starting cushion of buffer prepared in d2o and by stabilizing the liquid column above it with a d2o gradient. d2o/h2o mixtures have no apparent biochemical effects on the cells, and their physiochemical effects are short-lived and reversible. it was possible, by this method, to separate a mixture of glutaraldehyde-fixed erythrocytes of three species (rabb ...1979108673
bilateral ossification of the tendon of the biceps brachii muscle in the horse. 1979109425
protective and toxic effects of a nuclease-resistant derivative of polyriboinosinic-polyribocytidylic acid on venezuelan equine encephalomyelitis virus in rhesus monkeys.polyriboinosinic-polyribocytidylic acid, stabilized with poly-l-lysine and carboxymethylcellulose (poly iclc), favorably alters the pathogenesis of venezuelan equine encephalomyelitis virus infection in rhesus monkeys by decreasing the number of infected monkey that become detectably viremic and by delaying the onset of viremia in the remaining monkeys. poly iclc is known to induce high circulating levels of interferon in primates, and the interferon system is assumed to be the mechanism by whic ...1979109544
[mastocytoma in the horse]. 1979109918
[radiological examination of ossification processes in the withers of the horse]. 1979110007
[studies on sodium metabolism in the horse]. 1979110009
tricuspid atresia in a foal and a lamb. 1979110011
[comparative antiviral and interferonogenic activity of natural and synthetic interferon inducers in vitro and in vivo].biological activities of the rna replicative form of phage f2, a natural interferon inductor and poly-i -- poly-c, a synthetic polyribonucleotide complex were studied comparatively. differences in the comparative interferonogenic and antiviral activity of the inductors were as dependent on the type of the cell system. it was shown that deae-dextran increased the interferon-inducing activity of rff2 in the cell culture by 4 to 8 times. the dynamics of the interferonogenic and antiviral activity o ...1979110250
[myoglobin content and oxygen tension in the muscle tissues in allergic reactions].the influence of sensitization to horse serum, brucelia and bcg, and the allergic reactions induced by these antigens, on the oxygen tension and myoglobin content in the muscle tissues was studied. the lowering of myoglobin concentration associated with higher sensitivity formation was noted only in sensitization to living microbial strains. the allergic responses of immediate and delayed types provoked the decrease in myoglobin content both in the heart and skeletal muscles. the tension of oxyg ...1979110378
adjuvant effects of low doses of a nuclease-resistant derivative of polyinosinic acid . polycytidylic acid on antibody responses of monkeys to inactivated venezuelan equine encephalomyelitis virus vaccine.polyriboinosinic.polyribocytidylic acid [poly(i).poly(c)] stabilized with poly-l-lysine and carboxymethylcellulose [poly(iclc)] has been previously shown to be a compound with marked adjuvant activity when given in high doses with inactivated venezuelan equine encephalomyelitis (vee) virus vaccine. this study investigated the effects of much lower doses of poly(iclc) on the magnitude and kinetics of the primary and secondary humoral antibody responses of rhesus monkeys to inactivated vee virus v ...1979110688
immunosuppression by a mouse tumor resembles antigenic competition.the intraperitoneal injection of gamma-radiated, uv-radiated, or unradiated p-815 tumor cells into syngeneic or allogeneic mice suppressed the immune response to a subsequent intraperitoneal injection of sheep erythrocytes in a manner similar to the suppression caused by the injection of manner similar to the suppression caused by the injection of horse erythrocytes and termed antigenic competition. in both cases, the greatest suppression occurred when the sheep erythrocytes were injected at the ...1979111246
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