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ultrasonic assessment of pregnancy and fetal development in three species of macaque monkeys.serial ultrasonic assessments of gestational sac (gs) and fetal biparietal diameter (bpd) were performed in the japanese monkey (macaca fuscata fuscata), rhesus monkey (macaca mulatta), and crab-eating monkey (macaca fascicularis). in the japanese monkey, gs increased linearly for 3-8 weeks, whereas bpd increased in a linear-quadratic manner over 8 weeks to term. ultrasonic assessments of spontaneously aborted fetuses with bpd growth retardation and diagnosis of a pelvic chocolate cyst also were ...19883068367
identification of human saliva by antisera to alpha-amylase in human salivary glands.amylase activities were detected significantly in saliva from human, macaques and rodents and slightly in the vegetable and fruit extracts. dried stains on filter paper prepared from human and mammalian saliva, and the vegetable and fruit extracts were subjected to starch-iodine test and blue starch polymer-agar plate test. both tests showed strong positive reactions with the macaque and rodent saliva stains as well as human, but the vegetable and fruit stains showed clear positive reactions onl ...19863103259
[combined heart-lung transplantation in the japanese monkey]. 19873108559
effect of dietary cholesterol on production of lipoproteins and apolipoproteins by perfused livers from japanese monkeys (macaca fuscata).isolated livers from japanese monkeys were perfused for the purpose of characterizing low density lipoprotein (ldl) secreted directly by the liver, and for determining whether cholesterol feeding affects the hepatic production of ldl. perfusate containing [3h]leucine was recirculated for 60 min, followed by perfusion with fresh perfusate for two additional 2-h periods. radiolabelled lipoproteins, which are isolated by ultracentrifugation as very low density lipoprotein (vldl), ldl, and high dens ...19873123251
effect of dietary cholesterol on production of lipoproteins and apolipoproteins by perfused livers from japanese monkeys (macaca fuscata).isolated livers from japanese monkeys were perfused for the purpose of characterizing low density lipoprotein (ldl) secreted directly by the liver, and for determining whether cholesterol feeding affects the hepatic production of ldl. perfusate containing [3h]leucine was recirculated for 60 min, followed by perfusion with fresh perfusate for two additional 2-h periods. radiolabelled lipoproteins, which are isolated by ultracentrifugation as very low density lipoprotein (vldl), ldl, and high dens ...19873123251
sensory innervation of the periodontal ligament in the incisor and molar of the monkey, macaca fuscata. an immunohistochemical study for neurofilament protein and glia-specific s-100 protein.nervous elements in the periodontal ligament of the monkey, macaca fuscata were investigated by means of immunohistochemistry for neurofilament protein (nfp) and s-100 protein. thick nerve bundles with nfp-immunoreactivity entered the periodontal ligament through slits at the bottom of the alveolar socket, whereas thinner bundles, also nfp-immunoreactive, penetrated the ligament from the lateral wall of the alveolar socket. the nfp-immunopositive nerve fibers were densely distributed around the ...19873125817
[orthotopic heart and lung transplantation in the japanese monkey]. 19883133434
novel hemoglobin components and their amino acid sequences from the crab-eating macaque (macaca fascicularis).we found two types of hemoglobin, t and r, from the crab-eating macaque and compared those to a and q previously reported. the 22 animals studied showed six different phenotypes, a, r, qa, qt, qat, and qar. analysis of the complete amino acid sequences for the alpha chains of hemoglobins q, a, t, and r revealed that amino acids at four positions, 8, 55, 71, and 78 from the n-terminal, are variable. in the alpha a chain, thr, val, gly, and gln occupy these positions, and in the alpha q chain the ...19883148734
distribution of neurotensin-like immunoreactivity in the central nervous system of the formosan monkey.the distribution of neurotensin-like immunoreactivity was investigated in the central nervous system of the formosan monkey employing immunohistochemical techniques. neurotensin-containing cells were found to be widely distributed in the forebrain. the principal densities of neurotensin-like neuronal perikarya were located in the limbic system, the basal ganglion and the cerebral cortex; particularly in the amygdala, the septum, the neostriatum, the claustrum and the insula. the stria terminalis ...19883149760
quantitative autoradiographic localization of prostaglandin e2 binding sites in monkey diencephalon.quantitative autoradiography was performed to investigate the mapping of prostaglandin e2 binding sites in the macaca fuscata fuscata diencephalon. autoradiographs were prepared by incubation of 10-micron-thick serial frozen sections with 3h-prostaglandin e2 and were processed by using a rotating drum-scanner and a computer-assisted image-processing system with 3h-microscales as standards. the localization of prostaglandin e2 binding sites was remarkably discrete in the diencephalon. the highest ...19883164357
[experimental and clinical studies on free toe-joint transplantation to replace a finger joint by microvascular technic].major vascular pattern of the toe joints was investigated with template and transparent specimens in ten lower limbs of five japanese monkeys and seven adult human amputated lower limbs. this led to the conclusion that the metatarsal artery should be used for toe mp joint grafts, while the unilateral proper digital artery is suitable for toe pip joint grafts, together with concomitant or dorsal cutaneous vein. twelve pip and nine mp joints, a total of twenty-one experimentally grafted monkey toe ...19883171279
[experimental and clinical studies on free toe-joint transplantation to replace a finger joint by microvascular technic].major vascular pattern of the toe joints was investigated with template and transparent specimens in ten lower limbs of five japanese monkeys and seven adult human amputated lower limbs. this led to the conclusion that the metatarsal artery should be used for toe mp joint grafts, while the unilateral proper digital artery is suitable for toe pip joint grafts, together with concomitant or dorsal cutaneous vein. twelve pip and nine mp joints, a total of twenty-one experimentally grafted monkey toe ...19883171279
morphological features of iris fibroblasts in dilator muscle region.morphological features of iris fibroblasts in the dilator muscle region of the japanese monkey iris were demonstrated by transmission and scanning electron microscopy. the iris fibroblasts in the dilator muscle region formed the boundary between the dilator muscle and the iris stroma. these iris fibroblasts were characteristically accompanied by numerous naked axonal varicosities containing synaptic vesicles on the dilator muscle side. when viewed by scanning electron microscopy, the stromal sur ...19883184548
origin of lingual proprioceptive afferents in japanese monkey, m. fuscata fuscata. studied by hrp-labeling technique.the peripheral course of the axon of the lingual proprioceptive neurons in 5 japanese monkeys was studied by injecting hrp into the distal part of the hypoglossal nerve through the proximal stump. the present authors confirmed that the hrp-labeled cell bodies appeared ipsilaterally in the c2, c3 and c4 spinal ganglia. the afferents to the c2, c3 and c4 ganglia pass through the ansa hypoglossi and direct neuronal anastomosis existing between the first cervical nerve and the hypoglossal nerve. it ...19883189827
origin of lingual proprioceptive afferents in japanese monkey, m. fuscata fuscata. studied by hrp-labeling technique.the peripheral course of the axon of the lingual proprioceptive neurons in 5 japanese monkeys was studied by injecting hrp into the distal part of the hypoglossal nerve through the proximal stump. the present authors confirmed that the hrp-labeled cell bodies appeared ipsilaterally in the c2, c3 and c4 spinal ganglia. the afferents to the c2, c3 and c4 ganglia pass through the ansa hypoglossi and direct neuronal anastomosis existing between the first cervical nerve and the hypoglossal nerve. it ...19883189827
scanning electron microscopic study of the capillary loops in the dermal papillae. skin of the hand of the japanese monkey (macaca fuscata).the microvasculature of the skin of the hand of japanese monkeys was examined by means of scanning electron microscopy of corrosion casts. the vasculature of all areas of the skin of the hand was examined and divided into three structures excluding the nail bed: (1) in the ball of the finger, the typical structure of the capillary loops was studied. capillary loops were formed out of not just one capillary vessel, but two or three vessels. each capillary vessel arose and divided into several bra ...19883195308
scanning electron microscopic study of the capillary loops in the dermal papillae. skin of the hand of the japanese monkey (macaca fuscata).the microvasculature of the skin of the hand of japanese monkeys was examined by means of scanning electron microscopy of corrosion casts. the vasculature of all areas of the skin of the hand was examined and divided into three structures excluding the nail bed: (1) in the ball of the finger, the typical structure of the capillary loops was studied. capillary loops were formed out of not just one capillary vessel, but two or three vessels. each capillary vessel arose and divided into several bra ...19883195308
intraretinal axons of ganglion cells in the japanese monkey (macaca fuscata): conduction velocity and diameter distribution.in anesthetized and immobilized japanese monkeys (macaca fuscata), intraretinal conduction velocities of the ganglion cell axons were measured. the field potentials elicited by optic chiasm shocks consisted of fast and slow components with estimated conduction velocities of 1.19 and 0.72 m/s in recordings from the optic nerve fiber layer, and 1.65 and 1.00 m/s in recordings from the ganglion cell layer. single cell recordings verified that the time course of the fast component corresponded to th ...19883200520
intraretinal axons of ganglion cells in the japanese monkey (macaca fuscata): conduction velocity and diameter distribution.in anesthetized and immobilized japanese monkeys (macaca fuscata), intraretinal conduction velocities of the ganglion cell axons were measured. the field potentials elicited by optic chiasm shocks consisted of fast and slow components with estimated conduction velocities of 1.19 and 0.72 m/s in recordings from the optic nerve fiber layer, and 1.65 and 1.00 m/s in recordings from the ganglion cell layer. single cell recordings verified that the time course of the fast component corresponded to th ...19883200520
japanese monkeys' cardiac responses to visual depth.the present study examined the heart-rate changes which occurred in the visual-depth situation of japanese monkeys (macaca fuscata). four animals were tested over the first four weeks of age in the visual pitfall designed as a modification of the visual cliff. the infant monkeys showed heart-rate reduction in the depth condition. this reduction was observed from the first week and became remarkable at the third week. there were no differences in heart-rate change between monocular and binocular ...19883211685
japanese monkeys' cardiac responses to visual depth.the present study examined the heart-rate changes which occurred in the visual-depth situation of japanese monkeys (macaca fuscata). four animals were tested over the first four weeks of age in the visual pitfall designed as a modification of the visual cliff. the infant monkeys showed heart-rate reduction in the depth condition. this reduction was observed from the first week and became remarkable at the third week. there were no differences in heart-rate change between monocular and binocular ...19883211685
helminth parasites of the japanese monkey, macaca fuscata fuscata in ehime prefecture, japan. 19883221609
density of toruli tactiles in the japanese monkey. 19883223602
curvature of the lumbar spine as a consequence of mechanical necessities in japanese macaques trained for bipedalism.if trained to walk bipedally at a juvenile age and over periods of some months or years, japanese monkeys gradually acquire a pronounced lordosis of the lumbar spine. this lordosis persists even in the 'normal', pronograde posture of these animals. it is due to a relative increase of the ventral lengths of the vertebral bodies. this morphological change is clearly an adaptation to the mechanical necessities of the upright body posture. our result is in complete accordance with the development of ...19883234983
curvature of the lumbar spine as a consequence of mechanical necessities in japanese macaques trained for bipedalism.if trained to walk bipedally at a juvenile age and over periods of some months or years, japanese monkeys gradually acquire a pronounced lordosis of the lumbar spine. this lordosis persists even in the 'normal', pronograde posture of these animals. it is due to a relative increase of the ventral lengths of the vertebral bodies. this morphological change is clearly an adaptation to the mechanical necessities of the upright body posture. our result is in complete accordance with the development of ...19883234983
maternal aggression by lactating group-living japanese macaque females.this study analyzed the influence of lactation on aggression by group-living japanese macaque females. data collected during 268 hr of observation showed that lactating females exhibited much more aggression than did females in any other reproductive condition under investigation. this postpartum aggression showed distinctive features in terms of time course during lactation and target selectivity but it was not characterized by a higher intensity and severity. aggression increased progressively ...19883235061
functional and histological changes in mesenteric arteries and aortas from monkeys fed a high cholesterol diet.treatment of japanese monkeys for 8 months with a high fat, high cholesterol diet produced atherosclerotic lesions in the aorta and mesenteric arteries, such as fatty dots, streaks and plaques, intimal thickening with accumulation of spindle-shaped cells and macrophages and endothelial cell flattening. contractile responses of mesenteric arteries from control and atherosclerotic monkeys to electrical stimulation of adrenergic nerves, norepinephrine and angiotensin ii did not differ, whereas cont ...19883244199
functional and histological changes in mesenteric arteries and aortas from monkeys fed a high cholesterol diet.treatment of japanese monkeys for 8 months with a high fat, high cholesterol diet produced atherosclerotic lesions in the aorta and mesenteric arteries, such as fatty dots, streaks and plaques, intimal thickening with accumulation of spindle-shaped cells and macrophages and endothelial cell flattening. contractile responses of mesenteric arteries from control and atherosclerotic monkeys to electrical stimulation of adrenergic nerves, norepinephrine and angiotensin ii did not differ, whereas cont ...19883244199
rank relations of juvenile and subadult natal males of barbary macaques (macaca sylvanus) at affenberg salem.rank relations of more than 100 juvenile and subadult natal barbary macaque males were analyzed. hierarchical relations among individuals of the same age were established early during the first year of life. with few exceptions concerning infants from very high-ranking genealogies, males dominated female peers regardless of maternal rank. males started to outrank females from older cohorts during the second year of life and completed the process of rank reversal with adult females at 5-6 years o ...19883251819
[two cases of anomaly of the lower third molar in macaca fuscata fuscata]. 19883253577
[metrical study on teeth and mandible in macaca fuscata fuscata (japanese monkey)]. 19883253599
age gradations in vocalization and body weight in japanese monkeys (macaca fuscata).449 syllables in 174 food calls of japanese monkeys of various ages were analyzed spectrographically. the fundamental frequency bands were divided into 55 frequency modulation patterns. the percentage of harsh syllables changed with age class among adults. although the duration of syllables did not change with age, the maximum fundamental frequency and the minimum fundamental frequency showed age-related changes. both were distinctly decreased by 6-8 years of age and thereafter the decline was f ...19883254854
age gradations in vocalization and body weight in japanese monkeys (macaca fuscata).449 syllables in 174 food calls of japanese monkeys of various ages were analyzed spectrographically. the fundamental frequency bands were divided into 55 frequency modulation patterns. the percentage of harsh syllables changed with age class among adults. although the duration of syllables did not change with age, the maximum fundamental frequency and the minimum fundamental frequency showed age-related changes. both were distinctly decreased by 6-8 years of age and thereafter the decline was f ...19883254854
distribution of neurotensin-like immunoreactivity in the diencephalon of the japanese monkey (macaca fuscata).the distribution of neurotensin-like immunoreactive (nt-li) neurons was examined in the thalamus and hypothalamus of the japanese monkey (macaca fuscata) by using the peroxidase-antiperoxidase immunocytochemistry technique. in the thalamus, nt-li neuronal perikarya were distributed mainly in the midline nuclear group and the dorsomedial nucleus, and partially in the intralaminar nucleus: immunoreactive fibers were mainly distributed in the midline nucleus, particularly in the nucleus rhomboidali ...19873301918
neuronal activity in the primate non-primary cortex is different from that in the primary motor cortex.this paper describes differences in the properties of single-cell activity in the primary and non-primary motor cortex of behaving monkeys (macaca fuscata). new findings were obtained in relation to two different behavioural paradigms. first, we found that a large number of non-primary motor cortex neurons exhibit selective or preferential relationships to either signal-triggered or self-paced movement. in the second series of experiments, monkeys were trained to press a small key with the right ...19873322712
a highly specific and sensitive sandwich enzyme immunoassay for human hemoglobin a.a highly specific and sensitive sandwich enzyme immunoassay for human hemoglobin a (hb a) is described. a rabbit anti-human hb a igg-coated polystyrene ball was incubated with human hb a and subsequently with affinity-purified anti-human hb a fab'-horseradish peroxidase conjugates, which had been prepared before and after absorption with japanese monkey hb-sepharose 4b and dog hb-sepharose 4b. bound peroxidase activity was measured by fluorimetry using 3-(4-hydroxyphenyl)propionic acid as a subs ...19873322993
[neuroanatomical study of experimental tremor produced by vmt lesion in monkeys--a horseradish peroxidase study].destruction of the ventromedial tegmentum (vmt) of the midbrain in monkeys is known to produce tremors similar to those seen in parkinson's disease. to elucidate such tremorgenic mechanisms, 50% horseradish peroxidase (hrp) was injected into the vmt target region in three monkeys (macaca fuscata fuscata) and eleven adult cats. the volume injected varied between 0.05 and 0.1 microliter. the results suggest that afferent fibers to the thalamus, which passed through the vmt region, contains tractus ...19883362296
absolute auditory thresholds in three old world monkey species (cercopithecus aethiops, c. neglectus, macaca fuscata) and humans (homo sapiens).we investigated the absolute auditory sensitivities of three monkey species (cercopithecus aethiops, c. neglectus, and macaca fuscata) and humans (homo sapiens). results indicated that species-typical variation exists in these primates. vervets, which have the smallest interaural distance of the species that we tested, exhibited the greatest high-frequency sensitivity. this result is consistent with masterton, heffner, and ravizza's (1969) observations that head size and high-frequency acuity ar ...19883396316
absolute auditory thresholds in three old world monkey species (cercopithecus aethiops, c. neglectus, macaca fuscata) and humans (homo sapiens).we investigated the absolute auditory sensitivities of three monkey species (cercopithecus aethiops, c. neglectus, and macaca fuscata) and humans (homo sapiens). results indicated that species-typical variation exists in these primates. vervets, which have the smallest interaural distance of the species that we tested, exhibited the greatest high-frequency sensitivity. this result is consistent with masterton, heffner, and ravizza's (1969) observations that head size and high-frequency acuity ar ...19883396316
neuronal activity in cortical motor areas related to ipsilateral, contralateral, and bilateral digit movements of the monkey.1. single cell activity was studied in the precentral (pcm), premotor (pm), and supplementary (sma) motor cortex of the monkey to compare magnitudes of activity changes in relation to ipsilateral, contralateral, and bilateral digit movements. 2. three japanese monkeys were trained to press a small key with the right or left hand, or with both hands, in accordance with visual instruction signals given 2.6-5.4 s before a visual movement-trigger signal. great care was taken to train the animal to u ...19883404223
neuronal activity in cortical motor areas related to ipsilateral, contralateral, and bilateral digit movements of the monkey.1. single cell activity was studied in the precentral (pcm), premotor (pm), and supplementary (sma) motor cortex of the monkey to compare magnitudes of activity changes in relation to ipsilateral, contralateral, and bilateral digit movements. 2. three japanese monkeys were trained to press a small key with the right or left hand, or with both hands, in accordance with visual instruction signals given 2.6-5.4 s before a visual movement-trigger signal. great care was taken to train the animal to u ...19883404223
specific binding of peanut agglutinin to foveal and peripheral cone photoreceptors of monkey retina.peanut agglutinin, a lectin with specific affinity for galactose beta-(1----3)-n-acetyl-galactosamine disaccharides, showed binding to the slender cones in the rod-free fovea as well as to the conical cones in the periphery of the monkey (macaca fuscata) retina, but not to the rods, as revealed by light-microscopic cytochemistry with horseradish-peroxidase-conjugated lectin.19883419786
insoluble uricase in liver peroxisomes of old world monkeys.1. subcellular localization form and properties of liver uricase of macaca fascicularis were examined. 2. uricase was present as the insoluble form in the peroxisomal core. 3. evidence was obtained to show that the peroxisomal core is uricase itself. 4. the number and mol. wts of the subunits of the enzyme were identical to those of rat liver uricase. 5. the same results were also obtained for liver uricase of macaca fuscata.19873427896
specialization of the interphotoreceptor matrices around cone and rod photoreceptor cells in the monkey retina, as revealed by lectin cytochemistry.the binding sites of two lectins, peanut agglutinin (pna) and wheat germ agglutinin (wga), in the interphotoreceptor matrix (ipm) and photoreceptor plasma membranes of the japanese monkey (macaca fuscata) retina were localized using a pre-embedding staining method with ferritin-conjugated (fer) lectins as well as a postembedding staining method with fluorescence-labeled (fitc) lectins. fitc-pna, but not wga, stained cylindrical domains of the ipm around cone outer and inner segments, while the i ...19873428401
[reproductive pharmacology of prostaglandins].effects of prostaglandins and their analogues in reproduction were investigated using rats and japanese monkeys. prostaglandin of the f series exerted uterine contractile, luteolytic, anti-nidation and abortifacient effects. prostaglandins of the e series exhibited a potent uterine contractile effect, although their luteolytic, anti-nidation and abortifacient effects were much less potent than those of the pgf series. a comparison of animal and human data on prostaglandins and their analogues in ...19873429986
[reproductive pharmacology of prostaglandins].effects of prostaglandins and their analogues in reproduction were investigated using rats and japanese monkeys. prostaglandin of the f series exerted uterine contractile, luteolytic, anti-nidation and abortifacient effects. prostaglandins of the e series exhibited a potent uterine contractile effect, although their luteolytic, anti-nidation and abortifacient effects were much less potent than those of the pgf series. a comparison of animal and human data on prostaglandins and their analogues in ...19873429986
comparison of fecal microflora between wild japanese monkeys in a snowy area and laboratory-reared japanese monkeys. 19873430917
comparison of fecal microflora between wild japanese monkeys in a snowy area and laboratory-reared japanese monkeys. 19873430917
amygdalar connections with middle and inferior temporal gyri of the monkey.the origins and terminations of the amygdalar connections with middle (itm) and inferior temporal (iti) gyri of inferotemporal cortex (area te) were studied in japanese monkeys by the horseradish peroxidase method. the itm gyrus received a major projection from the lateral basal nucleus and a minor one from the accessory basal nucleus of the amygdala, whereas it sent a major projection to the lateral nucleus and a minor one to the lateral basal nucleus. the iti gyrus had only minor amygdalar pro ...19873441299
amygdalar connections with middle and inferior temporal gyri of the monkey.the origins and terminations of the amygdalar connections with middle (itm) and inferior temporal (iti) gyri of inferotemporal cortex (area te) were studied in japanese monkeys by the horseradish peroxidase method. the itm gyrus received a major projection from the lateral basal nucleus and a minor one from the accessory basal nucleus of the amygdala, whereas it sent a major projection to the lateral nucleus and a minor one to the lateral basal nucleus. the iti gyrus had only minor amygdalar pro ...19873441299
weaning variability in semi-free-ranging japanese macaques (macaca fuscata).the purpose of this research was to investigate variability in the weaning behaviours of japanese macaque (macaca fuscata) mothers and their infants and to attempt to define factors contributing to this variability. the marked level of variability in maternal weaning behaviours was unrelated to traditional sociological factors, such as the rank, parity, age and number of immature offspring of the mother, and the sex of the infant. the only variability in the weaning behaviours of the infants occ ...19873443417
[central distribution of masticatory and lingual proprioceptive afferents relative to jaw and tongue movements--part ii. lingual proprioceptive afferents of japanese monkey]. 19873479508
pneumocystis infection in macaque monkeys: macaca fuscata fuscata and macaca fascicularis.retrospective examination of lungs from 128 monkey necropsies was attempted for pneumocystis infection using special strains, including toluidine blue-o and gomori's methenamine silver nitrate. four japanese monkeys (7.7%), macaca fuscata fuscata, and one crab-eating monkey (7.7%), macaca fascicularis, were found to have pneumocystis infection. the organism was found in young and infant animals. at the time of death, one infant and two young monkeys were debilitated and/or emaciated. pneumocysti ...19873497397
pneumocystis infection in macaque monkeys: macaca fuscata fuscata and macaca fascicularis.retrospective examination of lungs from 128 monkey necropsies was attempted for pneumocystis infection using special strains, including toluidine blue-o and gomori's methenamine silver nitrate. four japanese monkeys (7.7%), macaca fuscata fuscata, and one crab-eating monkey (7.7%), macaca fascicularis, were found to have pneumocystis infection. the organism was found in young and infant animals. at the time of death, one infant and two young monkeys were debilitated and/or emaciated. pneumocysti ...19873497397
the genetic consequences of primate social organization: a review of macaques, baboons and vervet monkeys.primates, as long-lived, iteroparous, socially complex mammals, offer the opportunity to assess the effects of behavior and demography on genetic structure. because it is difficult to obtain tissue samples from wild primate populations, research in this area has largely been confined to terrestrial and semi-terrestrial old world monkeys (e.g., rhesus and japanese macaques, vervets and several subspecies of baboons). however, these species display a multi-male, multi-female social structure commo ...19873505885
distributional pattern of serotonin-immunoreactive nerve fibers in the lateral geniculate nucleus of the rat, cat and monkey (macaca fuscata).the distribution of serotonin-containing nerve fibers in the lateral geniculate nucleus (lgn) of the rat, cat, and monkey (macaca fuscata) was studied by use of the peroxidase-antiperoxidase method and an antiserum against serotonin. in all three species, the pattern of fibers was denser in the ventral portion of the lgn (lgnv) than in the dorsal nuclear portion (lgnd). in the lgnd of rat, serotonin-immunoreactive fibers were evenly distributed in the form of a dense network, but in cat and monk ...19863512095
the complete amino acid sequence of monkey pepsinogen a.the complete amino acid sequence of pepsinogen a from the japanese monkey (macaca fuscata) was determined. after converting the pepsinogen to pepsin by activation, the pepsin moiety was reduced and carboxymethylated, cleaved by cyanogen bromide, and the amino acid sequences of the major fragments determined. these fragments were aligned with the aid of overlapping peptides isolated from a chymotryptic digest of intact pepsin. since the sequence of the activation segment had been determined previ ...19863514596
the complete amino acid sequence of monkey progastricsin.the complete amino acid sequence of progastricsin from the japanese monkey (macaca fuscata) was determined. progastricsin is composed of 374 residues, including the gastricsin moiety of 331 residues and the activation segment of 43 residues. upon activation under acidic conditions, progastricsin was converted to gastricsin via the intermediate protein species. nh2-terminal sequence determination of these protein species enabled us to deduce the nh2-terminal 78-residue sequence of progastricsin, ...19863514597
characteristic pattern of monoaminergic nerve fibers in the pineal organ of the monkey, macaca fuscata.monoaminergic nerve fibers were studied in the pineal organ of the monkey. macaca fuscata, by use of fluorescence and immunohistochemical procedures. abundant formations of noradrenergic nerve fibers were observed in the pineal organ. they entered the parenchyma in the form of several coarse bundles via the capsule in the distal portion of the organ and spread throughout the organ after branching into smaller units. the density of the autonomic innervation decreased gradually toward the proximal ...19863527429
human renin inhibiting dipeptide.kri-1177, a dipeptide containing nor-statine inhibited renin activity in human and japanese monkey plasma to a markedly greater extent than that in dog, rabbit and rat plasma. the systemic blood pressure of anesthetized monkeys was lowered by intravenous injections of this compound which also reduced plasma renin activity and concentration of angiotensins. kri-1177 appears to selectively inhibit primate renin activity, thereby producing hypotension.19863536533
distribution of cerebellar neurons projecting directly to the spinal cord: an hrp study in the japanese monkey and the cat.distribution of cerebellar neurons which send their axons to the spinal cord was examined in 7 japanese monkeys (macaca fuscata) and 10 cats by the horseradish peroxidase (hrp) method; retrograde hrp-labeling of cerebellar neurons was observed after hrp injection into the spinal cord. the vast majority of cerebellospinal neurons were located in the fastigial nucleus (fn), posterior interpositus nucleus (pin), and intermediate medullary region (imr) between the fn and pin. these neurons were sugg ...19873598173
distribution of cerebellar neurons projecting directly to the spinal cord: an hrp study in the japanese monkey and the cat.distribution of cerebellar neurons which send their axons to the spinal cord was examined in 7 japanese monkeys (macaca fuscata) and 10 cats by the horseradish peroxidase (hrp) method; retrograde hrp-labeling of cerebellar neurons was observed after hrp injection into the spinal cord. the vast majority of cerebellospinal neurons were located in the fastigial nucleus (fn), posterior interpositus nucleus (pin), and intermediate medullary region (imr) between the fn and pin. these neurons were sugg ...19873598173
[experimental study of intraneural circulatory changes in axonal de- and regeneration].two experimental studies were made of intraneural circulatory change on axonal de- and regeneration using median and ulnar nerves of the japanese monkey. experiment 1: epineural suture was performed on one side, and fascicular suture was performed on the opposite side by removing the interfascicular epineurium. the regenerated axons in the fascicular suture group were fewer in number and smaller in diameter than those in the epineural suture group; this may have been the result of destruction of ...19873624964
representation of the main branches of the facial nerve within the facial nucleus of the japanese monkey (macaca fuscata).the facial nucleus of the japanese monkey was divided cytoarchitectonically into the ventral, medial, intermediate, dorsal and lateral divisions. when horseradish peroxidase (hrp) was applied to the inferior labial, cervical or posterior auricular branch of the facial nerve, hrp-labeled neurons were seen in the lateral, ventral or medial division of the facial nucleus, respectively. after applying hrp to the anterior auricular-zygomatico-orbital branch, labeled neurons were observed mainly in th ...19873627564
electrophysiologic properties differ in the ventricular endocardium and epicardium of the japanese monkey.we measured action potential duration (apd) from the endocardium (endo) and epicardium (epi) of the left ventricular free wall in japanese monkey hearts and found that the apd of endo is significantly longer than that of epi at a stimulus cycle length of 1500 msec in normal tyrode solution (control condition). we then hypothesized that shorter apd of epi results from greater outward pump current and that the difference in the current may be due to a difference in membrane na,k-atpase activity be ...19873655590
immunocytochemical localization of gamma-aminobutyric acid in the hypoglossal nucleus of the macaque monkey, macaca fuscata: a light and electron microscopic study.the hypoglossal nucleus of the macaque monkey macaca fuscata was investigated with light and electron microscopic immunocytochemistry with an antibody directed against gamma-aminobutyric acid (gaba). at the light microscopic level, gaba immunoreactivity was present in small neurons, punctate structures, and thin, fiberlike structures. these gaba-positive elements were distributed throughout the hypoglossal nucleus at rostrocaudal levels. there was no immunoreactivity in the hypoglossal motoneuro ...19873667970
an anatomical investigation on the muscles of the pelvic outlet in crab-eating monkey (macaca irus) and japanese monkey (macaca fuscata) with special reference to their nerve supply.for a fuller understanding of the nerve supply to the muscles of the pelvic outlet in man, 4 pelvic-halves of crab-eating monkeys and 6 pelvic-halves of japanese monkeys were minutely dissected. 1) the composition of the pudendal plexus tends to be limited to 2 segments, s1 and s2. 2) if we consider the origin of the nerves, the pudendal plexus is divided into 2, the first or medial and the second or lateral parts. from the first part arise the pelvic splanchnic nerves, the nerve to the iliopubo ...19873674454
an anatomical investigation on the muscles of the pelvic outlet in crab-eating monkey (macaca irus) and japanese monkey (macaca fuscata) with special reference to their nerve supply.for a fuller understanding of the nerve supply to the muscles of the pelvic outlet in man, 4 pelvic-halves of crab-eating monkeys and 6 pelvic-halves of japanese monkeys were minutely dissected. 1) the composition of the pudendal plexus tends to be limited to 2 segments, s1 and s2. 2) if we consider the origin of the nerves, the pudendal plexus is divided into 2, the first or medial and the second or lateral parts. from the first part arise the pelvic splanchnic nerves, the nerve to the iliopubo ...19873674454
vascular reactivities of simian ophthalmic and ciliary arteries.vascular reactivities to vasoactive substances were compared with ophthalmic and ciliary arteries (oas and cas) of japanese monkeys. these two kind of arteries were perfused with tyrode solution under a constant flow rate at 37 degrees c, respectively. each drug solution was given by a microinjector into the endothelial side of the artery through a cannulated tubing, and responses were obtained as changes in perfusion pressure. results were as follows: 1) norepinephrine induced vasoconstriction ...19873677779
vascular reactivities of simian ophthalmic and ciliary arteries.vascular reactivities to vasoactive substances were compared with ophthalmic and ciliary arteries (oas and cas) of japanese monkeys. these two kind of arteries were perfused with tyrode solution under a constant flow rate at 37 degrees c, respectively. each drug solution was given by a microinjector into the endothelial side of the artery through a cannulated tubing, and responses were obtained as changes in perfusion pressure. results were as follows: 1) norepinephrine induced vasoconstriction ...19873677779
[an experimental study of the function of the papillary sphincter and the pancreatic duct-acinar system as the regulatory mechanism of the pancreatic ductal pressure in the japanese monkey]. 19873682239
effect of paraquat on plasma fibronectin, serum free hydroxyproline, serum ceruloplasmin and lung collagen content in monkeys.the purpose of this study was to characterize paraquat toxicity in monkeys and to determine the feasibility of using the monkey as an animal model for the study of paraquat-induced pulmonary fibrosis in humans. sixteen japanese monkeys (macaca fuscata), more than 3.5 years of age, with bodyweight ranging from 3.2 kg to 10.2 kg, were randomly divided into two groups. they were administered paraquat dichloride (pq) by injection (s.c.) at a dose of 2.0 mg/kg bodyweight (12 monkeys) or s.c. saline, ...19873694721
effect of paraquat on plasma fibronectin, serum free hydroxyproline, serum ceruloplasmin and lung collagen content in monkeys.the purpose of this study was to characterize paraquat toxicity in monkeys and to determine the feasibility of using the monkey as an animal model for the study of paraquat-induced pulmonary fibrosis in humans. sixteen japanese monkeys (macaca fuscata), more than 3.5 years of age, with bodyweight ranging from 3.2 kg to 10.2 kg, were randomly divided into two groups. they were administered paraquat dichloride (pq) by injection (s.c.) at a dose of 2.0 mg/kg bodyweight (12 monkeys) or s.c. saline, ...19873694721
fine-structural study of the pineal body of the monkey (macaca fuscata) with special reference to synaptic formations.various types of synaptic formations on pinealocytes and pineal neurons were found in the pineal body of macaca fuscata. axo-somatic synapses of the gray type-ii category were detected on the pinealocyte cell body. gap junctions and ribbon synapses were observed between adjacent pinealocytes. about 70 nerve-cell bodies were detected in one half of the whole pineal body bisected midsagittally. they were localized exclusively deep in the central part. when examined electron-microscopically, they w ...19863719675
effect of small cue-response separation on pattern discrimination in macaques (macaca fuscata and m. mulatta).in order to elucidate the nature of the effect of small cue-response separations on pattern discriminations by monkeys, three studies were performed. when training on a pattern discrimination with a cue-response separation was discontinued during performance at the chance level, there was no saving on the rate of learning a second task (with identical cues but a different cue-response separation) relative to the performance of naive control animals. by contrast, when training was discontinued at ...19863720283
[circadian rhythms of the pancreatic ductal pressure and e.m.g. of the papillary sphincter in japanese monkey]. 19863723852
behavior of infant japanese monkeys (macaca fuscata) with congenital limb malformations during their first three months.locomotion and mother-infant interactions of a severely malformed, a slightly malformed, and a normal infant were observed in a free-ranging group of japanese monkeys (macaca fuscata). the severely malformed infant had no feet and had hands consisting of 2 digits. the slightly malformed infant had normal feet and hands consisting of 2 digits. the severely malformed infant was more retarded in development of posture and locomotion than the other infants; however, it developed locomotor patterns a ...19863732624
behavior of infant japanese monkeys (macaca fuscata) with congenital limb malformations during their first three months.locomotion and mother-infant interactions of a severely malformed, a slightly malformed, and a normal infant were observed in a free-ranging group of japanese monkeys (macaca fuscata). the severely malformed infant had no feet and had hands consisting of 2 digits. the slightly malformed infant had normal feet and hands consisting of 2 digits. the severely malformed infant was more retarded in development of posture and locomotion than the other infants; however, it developed locomotor patterns a ...19863732624
percentage of glycosylated hemoglobin and serum concentration of glucose in the blood of japanese macaques and in three exotic ruminant species.serum glucose concentrations and percentages of glycosylated hemoglobin (ghb) were determined in 16 japanese macaques and in 19 exotic ruminants (4 markhor, 5 mouflon, 10 aoudad). mean (+/- sd) serum glucose concentration and ghb percentage in the japanese macaques were 73 +/- 21.8 mg/dl and 4.7 +/- 0.82%, respectively. serum glucose concentration was considered within the normal range for this species. the mean ghb percentage was within the normal range for man, indicating that ghb may be a val ...19863752690
effect of unilateral and bilateral auditory cortex lesions on the discrimination of vocalizations by japanese macaques.ten japanese macaques were trained to discriminate between two types of japanese macaque coo vocalizations before and after auditory cortex ablation. five of the animals were tested following left unilateral ablation, whereas the other five were tested following right unilateral ablation. after postoperative testing, symmetrical lesions were made in the remaining hemisphere in two animals from each group and the effect of bilateral lesions was assessed. the animals were tested using a shock avoi ...19863783215
focal experimental demyelination in monkey optic nerve by lysophosphatidylcholine.the optic nerve of 2 adult male macaca fuscata was exposed and lysophosphatidylcholine dissolved in saline at 2% was slowly injected into the nerve at about 5 mm posteriorly from the eyeball. this procedure produced a focal lesion of demyelinating plaque. klüver-barreras and bodian stain for myelin and axon revealed demyelination with myelin ovoids and relatively well preserved axons in the focal plaque. it was thought that this lesion would be an experimental model of the demyelinating lesion o ...19853831492
distribution of human leumorphin-like immunoreactivity in the monkey spinal cord revealed by immunocytochemistry.the regional distribution of human leumorphin (hl)-like immunoreactivity (hl-li) in monkey (macaca fuscata) spinal cord and dorsal root ganglia was investigated by peroxidase-anti-peroxidase immunocytochemistry using specific antiserum. hl-li-positive fibers and terminals were distributed densely in laminae (rexed) i and ii, and sparsely in laminae iii-vii and x, but no immunoreactive elements were observed in the ventral horn, the white matter or the dorsal root ganglia. many immunoreactive neu ...19853840871
an hrp study in the monkey of olivary projections from the mesodiencephalic structures with particular reference to pretecto-olivary neurons.the cells of origin of the olivary projection from mesodiencephalic structures have been demonstrated in the japanese monkey (macaca fuscata) with the horseradish peroxidase (hrp) method. particular attention has been paid to the pretecto-olivary projection which is entirely ipsilateral and originates from the nucleus of the optic tract (not), the posterior (or principal) pretectal nucleus (ppn), the sublentiform nucleus (sl), and the (pretectal) ventral lateral zone (vlz). pretecto-olivary cell ...19853878693
monkey pepsinogens and pepsins. vii. analysis of the activation process and determination of the nh2-terminal 60-residue sequence of japanese monkey progastricsin, and molecular evolution of pepsinogens.japanese monkey progastricsin was shown to be activated to gastricsin exclusively by a two-step process through an intermediate form. the occurrence of this process was substantiated by the isolation of the intermediate form and released peptides. by nh2-terminal sequence analyses of these protein and peptide species, the amino acid sequence of the 43-residue activation segment (propart) was determined to be as follows: (formula: see text) the nh2-terminal 26-residue peptide was released first, ...19853928607
fibrinopeptides a and b of japanese monkey (macaca fuscata) and patas monkey (erythrocebus patas): their amino acid sequences, restricted mutations, and a molecular phylogeny for macaques, guenons, and baboons.amino acid sequences of fibrinopeptides a and b from the macaque, macaca fuscata (japanese monkey) and the guenon, erythrocebus patas (patas monkey) were established. fibrinopeptides a of the monkeys had a sequence identical with those of baboons: ala-asp-thr-gly-glu-gly-asp-phe-leu-ala-glu-gly-gly-gly-val-arg. fibrinopeptides b were 9-residue, "short," peptides with the sequences asn-glu-glu-ser-leu-phe-ser-gly-arg for m. fuscata and asn-glu-glu-val-leu-phe-gly-gly-arg for e. patas. the sequenc ...19853928610
purification of japanese monkey prostate acid protease zymogen and its identification as a pepsinogen c-like zymogen.a pepsinogen c-like acid protease zymogen was found in japanese monkey prostate extract and seminal plasma by means of the double immunodiffusion method using rabbit anti-pepsinogen c antiserum, and was purified from the prostate by a combination of ammonium sulfate fractionation, deae-sephacel chromatography, sephadex g-100 gel filtration, and immunoadsorption to an anti-pepsinogen c column. the zymogen was purified 6,400-fold in a yield of 13.1%. the purified zymogen gave a single band on poly ...19853936848
hearing loss in japanese macaques following bilateral auditory cortex lesions.the hearing ability of five japanese macaques (macaca fuscata) was assessed following two-stage bilateral auditory cortex lesions. the animals were tested using a shock-avoidance procedure with a conditioned-suppression procedure used for comparison in two cases. the animals initially were unable to respond to sound, and the first signs of hearing appeared as late as 13 wk after surgery. hearing levels improved gradually over time, with maximal recovery reached at 24-35 wk after surgery. recover ...19863950690
neutrophilic nodules in the intestinal walls of japanese monkeys associated with the neutrophil chemotactic activity of larval extracts and secretions of oesophagostomum aculeatum.high neutrophil chemotactic activity was detected in the culture medium from oesophagostomum aculeatum larvae in vitro using blind-well chambers with millipore filters, and guinea pig leucocytes as indicator cells. neutrophil chemotactic activity was also detected in the extract from larval worms in a dose dependent fashion. this activity was detected in the low molecular weight fractions adjacent to a sodium chloride marker by gel filtration on sephadex g200. these results were further confirme ...19853975475
neutrophilic nodules in the intestinal walls of japanese monkeys associated with the neutrophil chemotactic activity of larval extracts and secretions of oesophagostomum aculeatum.high neutrophil chemotactic activity was detected in the culture medium from oesophagostomum aculeatum larvae in vitro using blind-well chambers with millipore filters, and guinea pig leucocytes as indicator cells. neutrophil chemotactic activity was also detected in the extract from larval worms in a dose dependent fashion. this activity was detected in the low molecular weight fractions adjacent to a sodium chloride marker by gel filtration on sephadex g200. these results were further confirme ...19853975475
movement and non-movement related pallidal unit activity during bar press feeding behavior in the monkey.activity was recorded from 358 neurons in the globus pallidus (gp) of monkeys (macaca fuscata) during an operant feeding task consisting of 3 stages: (1) food or non-food presentation (1st stage); (2) bar pressing (2nd stage); and (3) food acquisition and ingestion (3rd stage). there were two kinds of neurons, one with high and the other with very low (almost silent), spontaneous firing rates. two hundred and four neurons (57%) responded in one or more of the feeding stages. of the 21 neurons wh ...19853977985
hippocampal unit activity and delayed response in the monkey.single unit activity was recorded from the hippocampus while japanese monkeys (macaca fuscata, n = 4) were performing a delayed response (dr) task. a total of 272 units showed an obvious change in discharge rate in relation to the events of the dr task. these 272 related units were classified into 6 groups: cue-light related units (n = 24), cue- and choice-light related units (n = 41), choice-light related units (n = 21), response-related units (n = 51), reward-error units (n = 17), and delay un ...19853978418
hippocampal unit activity and delayed response in the monkey.single unit activity was recorded from the hippocampus while japanese monkeys (macaca fuscata, n = 4) were performing a delayed response (dr) task. a total of 272 units showed an obvious change in discharge rate in relation to the events of the dr task. these 272 related units were classified into 6 groups: cue-light related units (n = 24), cue- and choice-light related units (n = 41), choice-light related units (n = 21), response-related units (n = 51), reward-error units (n = 17), and delay un ...19853978418
auditory short-term memory in the japanese monkey.auditory short-term memory in japanese monkeys (macaca fuscata) was studied using a go/no go auditory delayed matching to sample task. three temporal parameters: delay interval, intertrial interval and sample stimulus duration were manipulated. delayed matching performance deteriorated as the delay interval was lengthened, and reached a near chance level at 16 sec. longer intertrial intervals and sample duration ameliorated performance. when the number of the sample stimulus was increased to 3 t ...19853980158
auditory short-term memory in the japanese monkey.auditory short-term memory in japanese monkeys (macaca fuscata) was studied using a go/no go auditory delayed matching to sample task. three temporal parameters: delay interval, intertrial interval and sample stimulus duration were manipulated. delayed matching performance deteriorated as the delay interval was lengthened, and reached a near chance level at 16 sec. longer intertrial intervals and sample duration ameliorated performance. when the number of the sample stimulus was increased to 3 t ...19853980158
central distribution of efferent and afferent components of the pudendal nerve in macaque monkeys.central distribution of efferent and afferent components of the pudendal nerve was studied by the horseradish peroxidase (hrp) method in 13 macaque monkeys, i.e., in nine japanese monkeys (macaca fuscata), two rhesus monkeys (macaca mulatta), and two crab-eating monkeys (macaca fascicularis). the enzyme was applied to the central cut end of the pudendal nerve; then the monkeys were allowed to survive for 36 to 72 hr. retrogradely labeled neuronal cell bodies of pudendal motoneurons constituted a ...19853980767
central distribution of efferent and afferent components of the pudendal nerve in macaque monkeys.central distribution of efferent and afferent components of the pudendal nerve was studied by the horseradish peroxidase (hrp) method in 13 macaque monkeys, i.e., in nine japanese monkeys (macaca fuscata), two rhesus monkeys (macaca mulatta), and two crab-eating monkeys (macaca fascicularis). the enzyme was applied to the central cut end of the pudendal nerve; then the monkeys were allowed to survive for 36 to 72 hr. retrogradely labeled neuronal cell bodies of pudendal motoneurons constituted a ...19853980767
amygdalospinal projections in the macaque monkey.injection of horseradish peroxidase into the cervical cord in the macaque monkey led to the retrograde labeling of neurons in the caudal part of the central nucleus of the amygdala ipsilateral to the spinal half where the injection was made. although the number of labeled neurons in the amygdala was small, they were constantly found in 7 macaque monkeys (3 japanese monkeys, 3 crab-eating monkeys and 1 rhesus monkey) which were injected with the enzyme into the upper and middle cervical cord segm ...19853982715
amygdalospinal projections in the macaque monkey.injection of horseradish peroxidase into the cervical cord in the macaque monkey led to the retrograde labeling of neurons in the caudal part of the central nucleus of the amygdala ipsilateral to the spinal half where the injection was made. although the number of labeled neurons in the amygdala was small, they were constantly found in 7 macaque monkeys (3 japanese monkeys, 3 crab-eating monkeys and 1 rhesus monkey) which were injected with the enzyme into the upper and middle cervical cord segm ...19853982715
retroperitoneal fibromatosis and acquired immunodeficiency syndrome in macaques. pathologic observations and transmission studies.a peculiar fibroproliferative syndrome called retroperitoneal fibromatosis (rf) has been observed in macaca nemestrina, macaca mulatta, macaca fascicularis, and macaca fuscata at the washington regional primate research center. rf is characterized by the aggressive proliferation of highly vascular fibrous tissue subjacent to the peritoneum covering the ileocecal junction and associated mesenteric lymph nodes. in the early, proliferative phase of the disease, most of the fibroblastlike cells cont ...19853993741
neuropsychological basis of pattern vision in macaque monkeys.the central mechanisms of underlying pattern vision in macaques (rhesus and japanese monkeys) were investigated behaviorally and electrophysiologically. a series of studies indicated that there are two major processes underlying pattern vision. one of two processes is the process of attending selectively to pattern cues at background, with which inferior parietal cortex is concerned predominantly. the other is the process of pattern perception and cognition, in which inferotemporal cortex is inv ...19854024462
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