| responses of single neurons in the parietoinsular vestibular cortex of primates. | 1. neurons activated by stimulation of the horizontal and/or vertical vestibular semicircular canals were recorded in the parietoinsular vestibular cortex in four awake java monkeys (macaca fascicularis) and three squirrel monkeys (saimiri sciureus). steady tilt in darkness or during illumination of a vertically striped cylinder or of the normal laboratory surroundings did not lead to a significant change in pivc neuron activity. thus vestibular input to this cortical region seems to be restrict ... | 1988 | 3149165 |
| experimental infections of simians with human malaria: attempts to infect callithrix penicillata with plasmodium falciparum. | after reviewing the use of non-human primates of the old and new worlds for human malaria research, we concluded that another experimental animal which is easily available to use and possible to rear indoors is needed. thus, we studied the susceptibility of the marmoset callithrix penicillata to plasmodium falciparum erythrocytic infections. the marmosets received various p. falciparum human isolates, directly from a patient and from continuous cultures. the palo alto strain, which has been adap ... | 1987 | 3149726 |
| effect of human gamma interferon on yellow fever virus infection. | we studied yellow fever virus infection in two species of monkey: saimiri sciureus (squirrel monkeys) and macaca mulatta (rhesus monkeys). human gamma interferon was administered intravenously in five equal doses, one was given 24 hr before infection followed by four doses 24 hr apart. interferon reduced the levels and duration of viremia and the severity of hepatitis in squirrel monkeys. interferon prolonged survival time and delayed the appearance of viremia and hepatitis in infected rhesus mo ... | 1988 | 3152785 |
| [ultrastructural observations of follicular oocytes inseminated in vitro in squirrel monkeys (saimiri sciureus)]. | the ultrastructure of squirrel monkey (saimiri sciureus) follicular oocytes inseminated in vitro was studied at the endocrine research center of michigan state university in the united states. adult female squirrel monkeys were induced to ovulate with fsh-hcg, followed by laparoscopy 16 hours after hcg to collect ovarian follicular oocytes. a total of 45 oocytes were inseminated 21 hours after recovery by adding sperm collected by electroejaculation, followed by insemination culture for 24 hours ... | 1988 | 3171270 |
| efficacy of ivermectin against natural infection of strongyloides spp. in squirrel monkeys (saimiri sciureus). | | 1988 | 3184861 |
| elevation in plasma glucagon levels in response to stress in squirrel monkeys: comparisons of two subspecies (saimiri sciureus boliviensis and saimiri sciureus sciureus). | bolivian (bo) and brazilian (br) squirrel monkeys (sms) were captured and restrained to determine patterns of glucagon and glucose response. in both subspecies, plasma glucagon and glucose levels rose rapidly in response to restraint procedures; glucagon levels in brsms and glucose levels in both subspecies returned to basal values in 15 minutes. the magnitude of the glucagon and glucose responses differed significantly between bosms and brsms. | 1988 | 3193450 |
| erp responses to ethanol and diazepam administration in squirrel monkeys. | the effects of oral administration of two doses of ethanol (0.75 and 1.5 g/kg) and a single dose of diazepam (2.5 mg/kg) on electrophysiological responses to an event related potential (erp) paradigm were investigated in the squirrel monkey saimiri sciureus. a passive auditory "oddball plus novel" tone sequence was utilized to elicit n1, p2, n2, and p3-like components which resembled waveforms obtained from human subjects under the same conditions. ethanol at both doses was found to produce a si ... | 1988 | 3228483 |
| nocturnal vocalizations by squirrel monkeys (saimiri sciureus). | | 1988 | 3254847 |
| corticotropin-releasing factor in olivocerebellar climbing-fiber system of monkey (saimiri sciureus and macaca fascicularis): parasagittal and regional organization visualized by immunohistochemistry. | an antiserum directed against the human form of corticotropin-releasing factor (crf) was utilized for immunohistochemical visualization of the distribution of this peptide in the inferior olivary nucleus and cerebellum of 2 monkey species (saimiri sciureus, macaca fascicularis). colchicine pretreatment was not used. in both species, immunoreactivity was evident in the vast majority of neurons in the inferior olivary nucleus, with perikarya in the medial accessory olive exhibiting especially inte ... | 1988 | 3263473 |
| distribution of corticotropin-releasing-factor-like immunoreactivity in brainstem of two monkey species (saimiri sciureus and macaca fascicularis): an immunohistochemical study. | immunohistochemical methods were utilized to systematically map the distribution of corticotropin-releasing-factor-like immunoreactivity (crf-li) in the diencephalon, mesencephalon, and rhombencephalon of two monkey species (saimiri sciureus and macaca fascicularis). a primary antiserum directed against the human form of the peptide was utilized. immunoreactive neuronal perikarya and processes were evident in numerous areas, and the distributions of these elements were similar for the two specie ... | 1988 | 3265422 |
| glomerulopathy in squirrel monkeys with acute plasmodium falciparum infection. | the renal pathology of 9 squirrel monkeys (saimiri sciureus) with acute plasmodium falciparum infection was studied by light and electron microscopy. endocapillary proliferative glomerulonephritis was the major pathological change observed. the peroxidase anti-peroxidase method demonstrated the presence of igg, igm, and p. falciparum antigens in the mesangium and basement membrane. these findings were consistent with those seen in humans with acute p. falciparum infection and indicates that squi ... | 1988 | 3277466 |
| sporozoite-induced infections of the salvador i strain of plasmodium vivax in saimiri sciureus boliviensis monkeys. | twenty saimiri sciureus boliviensis monkeys from bolivia were inoculated intravenously with sporozoites of the salvador i strain of plasmodium vivax. all animals were splenectomized 7 days after inoculation. inoculation of 100,000 sporozoites resulted in prepatent periods averaging 16.6 days; all monkeys developed high-level parasitemias with an average maximum of 103,000 per mm3. inoculation of 10,000 sporozoites resulted in average prepatent periods of 19.4 days; one of the resulting infection ... | 1988 | 3294366 |
| distribution of gaba-immunoreactive neurons in the basal ganglia of the squirrel monkey (saimiri sciureus). | the distribution of gaba-immunoreactive neurons was visualized in the basal ganglia of the squirrel monkey (saimiri sciureus), by using a highly specific antiserum raised against gaba-glutaraldehyde-lysyl-protein conjugate and revealed by the indirect peroxidase-antiperoxidase immunohistochemical method. in the dorsal striatum, gaba-immunoreactive nerve cell bodies were small to medium in size (sectional area ranging from 90 to 125 microns2), but some larger ones (500-600 microns2) were also fou ... | 1987 | 3294929 |
| study of some parameters affecting the in vitro cultivation of plasmodium falciparum within saïmiri sciureus red blood cells. | the in vitro growth and multiplication of the erythrocytic stages of plasmodium falciparum within saïmiri sciureus (squirrel monkey) red blood cells have been studied. various parameters, such as the origin of the red blood cells and serum supplement, nature of the buffer, influence of the final ph of the medium, role of proteose peptone and glucose addition, were investigated. the selection of the best culture conditions led to the obtention of a reproducible in vitro growth of two parasite cyc ... | 1986 | 3295467 |
| pathologic changes associated with fatal plasmodium falciparum infection in the bolivian squirrel monkey (saimiri sciureus boliviensis). | fatal cases of experimental plasmodium falciparum (indochina i) in bolivian squirrel monkeys (saimiri sciureus boliviensis) were examined by histologic and ultrastructural methods. gross lesions were characterized by hepatosplenomegaly and interstitial pulmonary changes. histologically, there was marked diffuse reticuloendothelial hyperplasia, pulmonary alveolar septal thickening, mesangioproliferative glomerulonephropathy, sequestration of parasitized erythrocytes in deep vascular beds, degener ... | 1987 | 3300388 |
| chesson strain plasmodium vivax in saimiri sciureus boliviensis monkeys. | nine saimiri sciureus boliviensis monkeys were inoculated with sporozoites of plasmodium vivax (chesson strain) dissected from anopheles stephensi mosquitoes infected by feeding on blood from infected chimpanzees. the animals were splenectomized 7 days after inoculation. seven animals developed infections with prepatent periods ranging from 12 to 43 days (mean of 19.6 days). parasitemias were low during the first 50 days. maximum parasitemias in 5 animals in which the strain adapted ranged from ... | 1987 | 3309241 |
| distribution and morphological characteristics of dopamine-immunoreactive neurons in the midbrain of the squirrel monkey (saimiri sciureus). | the distribution and morphological characteristics of dopamine (da) neurons in the midbrain of the squirrel monkey (saimiri sciureus) were investigated by peroxidase-antiperoxidase (pap) immunohistochemistry with a highly specific antiserum raised against da-glutaraldehyde-lysyl-protein conjugate (donated by m. geffard). four contiguous areas contained da-immunostained nerve cell bodies: (1) the substantia nigra, pars compacta (snc), (2) the ventral tegmental area (vta), (3) the retrorubral area ... | 1988 | 3346372 |
| anatomical connections of the prepositus and abducens nuclei in the squirrel monkey. | the primary goal of this investigation was to identify the areas of the brainstem and cerebellum that provide afferent projections to the nucleus prepositus hypoglossi in primates. after horseradish peroxidase conjugated to wheat germ agglutinin (wga-hrp) was injected into the prepositus in squirrel monkeys (saimiri sciureus), the largest populations of retrogradely labeled neurons were found in the vestibular nuclei, the contralateral perihypoglossal nuclei, and the medullary and pontine reticu ... | 1988 | 3346381 |
| the nasotemporal division in primate retina: the neural bases of macular sparing and splitting. | in primates, each hemisphere contains a representation of the contralateral visual hemifield; unilateral damage to the visual pathways results in loss of vision in half of the visual field. apparently similar severe, unilateral lesions to the central visual pathways can result in two qualitatively different central visual field defects termed macular sparing and macular splitting. in macular sparing a 2 degrees to 3 degrees region around the fovea is spared from the effects of unilateral damage ... | 1988 | 3353708 |
| transmission of the os strain of plasmodium inui to saimiri sciureus boliviensis and aotus azarae boliviensis monkeys by anopheles dirus mosquitoes. | eight saimiri and 7 aotus monkeys were exposed to infection with the os strain of plasmodium inui via the bites of from 2 to 7 anopheles dirus mosquitoes. all saimiri monkeys developed high-level infections of from 152,000 to 500,000/mm3 after prepatent periods of from 14 to 17 days. only 1 aotus monkey developed a patent infection after a period of 28 days. feeding on these animals failed to result in infection of an. dirus mosquitoes. | 1988 | 3379532 |
| plasma lipoprotein alterations in squirrel monkeys (saimiri sciureus) during ethanol administration and abstinence. | the time course of lipoprotein changes during ethanol (etoh) consumption followed by abstinence was examined in 3 groups of male squirrel monkeys: 1) controls fed isocaloric liquid diet; 2) low etoh monkeys given liquid diet with vodka substituted isocalorically for carbohydrate at 12% of calories; and 3) high etoh animals fed diet plus vodka at 24% of calories. after 2 weeks, high etoh monkeys showed significant elevations in total plasma cholesterol which continued to increase at 4 weeks and t ... | 1988 | 3401294 |
| polymorphism of the middle wavelength cone in two species of south american monkey: cebus apella and callicebus moloch. | the spectral sensitivity of the middle wavelength cone was measured in two species of south american monkey, cebus apella and callicebus moloch, using electroretinogram (erg) flicker photometry. both of these species were found to have a polymorphism of the middle wavelength cone. eight male cebus monkeys each had only a single type of middle wavelength cone having lambda max values of either 550 or 562 nm. eight callicebus monkeys (7 male, 1 female) showed a similar polymorphism of the middle w ... | 1987 | 3424673 |
| organization of efferent projections of the subthalamic nucleus in the squirrel monkey as revealed by retrograde labeling methods. | the cellular origin and degree of collateralization of the subthalamostriatal, subthalamonigral and subthalamopallidal projections in the squirrel monkey (saimiri sciureus) were studied using lectin-conjugated horseradish peroxidase (wga-hrp), nuclear yellow (ny) and fast blue (fb) as retrograde tracers. in a first experimental group, wga-hrp was injected in the left putamen and the right caudate nucleus. following these injections numerous retrogradely labeled neurons occurred in the dorsolater ... | 1987 | 3435830 |
| early color deprivation and subsequent color vision in a dichromatic monkey. | a squirrel monkey (saimiri sciureus) was reared for the first 4 months of life in a dim, colorless environment. following an additional 10 months of normal visual experience, tests of color vision and spectral sensitivity were run on this animal and a control subject. the results suggest that the adult expression of dichromatic color vision does not depend on color experience during the first 4 months of life. | 1987 | 3447353 |
| inheritance of color vision in a new world monkey (saimiri sciureus). | squirrel monkeys (saimiri sciureus) have a striking color-vision polymorphism; each animal has one of six different types of color vision. these arise from individual variation in the presence of three different middle- to long-wavelength cone pigments. the distribution of cone phenotypes was established for a large sample of squirrel monkeys, including several families, through analysis of a retinal gross potential. the results indicate that the inheritance of color vision in the squirrel monke ... | 1987 | 3470811 |
| symptoms and behavioral features induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) in an old java monkey [macaca cynomolgus fascicularis (raffles)]. | the study concerns symptoms and behavioral characteristics induced by mptp in a 20-year-old macaca cynomolgus fascicularis, their evolution over 7 months, and the animal's response to 1-dopa treatment. the symptoms which the animal developed include those that have been described earlier in macaca mulatta and saimiri sciureus, i.e., rigidity, action tremor, postural tremor, postural flexion, hypokinesia, and bradykinesia. in addition, however, the animal developed a 3.8 hz resting tremor which i ... | 1986 | 3488798 |
| [elisa test in sero-epidemiologic studies of human malaria. evaluation of an antigen prepared from erythrocytes of saimiri sciureus experimentally infected with plasmodium falciparum]. | a soluble antigen was prepared from squirrel monkeys (saimiri sciureus) infected with blood-passaged plasmodium falciparum, and evaluated in an enzyme-linked immunosorbent assay (elisa) as a potent antigen for malaria diagnostic. the specificity, reproducibility and sensibility of the test showed the suitability of our antigenic preparation in detecting antibodies, igg and igm, in patients with p. falciparum infections. thus, the saimiri monkey represents an interesting alternative to the classi ... | 1986 | 3516425 |
| adaptation of the indochina i/cdc strain of plasmodium falciparum to the squirrel monkey (saimiri sciureus). | the indochina i/cdc strain of plasmodium falciparum was linearly passaged in squirrel monkeys (saimiri sciureus) of 3 phenotypes. splenectomized monkeys of guyanan and peruvian type developed high density parasitemias, but considerably lower than the mean peak parasitemia (greater than 10(6)/mm3) in bolivian phenotype squirrel monkeys. spleen-intact bolivian and peruvian squirrel monkeys all developed potentially lethal infections after linear passage of parasites from saimiri and aotus. for the ... | 1986 | 3518503 |
| in vitro and in vivo adaptation of the geneve/sge-1 strain of plasmodium falciparum to growth in a squirrel monkey (saimiri sciureus) model. | human erythrocytic culture-adapted parasites of the geneve/sge-1 strain of plasmodium falciparum were successfully adapted to grow in an in vitro culture system containing squirrel monkey erythrocytes and serum. these monkey culture-adapted organisms were then used to produce a patent infection in a splenectomized squirrel monkey. fresh infected blood from this animal was introduced into another splenectomized monkey and was subsequently serially passed through seven intact squirrel monkeys. hig ... | 1987 | 3548448 |
| human and primate malarial sera inhibit fc receptor-mediated phagocytosis. | sera obtained from humans in p. falciparum-endemic regions and from p. vivax-infected saimiri sciureus were assayed for their ability to inhibit fc receptor-mediated phagocytosis. some sera of humans exposed to p. falciparum from the gambia, sudan, and thailand inhibited ingestion via the fc receptor by normal human monocytes. in addition, sera from infected monkeys and a high molecular weight fraction of infected monkey serum inhibited ingestion of eigg by normal monkey spleen macrophages. gene ... | 1987 | 3548450 |
| characterization of a 96-kilodalton thermostable polypeptide antigen of plasmodium falciparum related to protective immunity in the squirrel monkey. | protective immunity against plasmodium falciparum malaria in the squirrel monkey (saimiri sciureus) is, in part, antibody mediated. we have previously shown that polypeptides of 41, 76, and 96 kilodaltons (kda) are specifically immunoprecipitated with monkey sera which are protective in passive transfer experiments. we report here that three different 96-kda polypeptides, of pi 5.15, 5.25, and 5.35, can be visualized when parasite extracts are analyzed in bidimensional gels. only one of them (of ... | 1987 | 3552999 |
| induction of follicular growth in the squirrel monkey (saimiri sciureus): enhanced recovery of mature ova for fertilization in vitro. | in order to improve the rate of recovery of mature ova over those previously reported, we evaluated a new hormonal regimen for induction of follicular growth in the squirrel monkey. this regimen, which consisted of 50 iu pregnant mare's serum (pms) per day for 4 days followed by 50 iu pms and 250 iu human chorionic gonadotropin (hcg) on the 5th day, gave an average yield of 2.3 mature ova per animal from 14 experiments involving 11 animals. ova were recovered through laparotomy or laparoscopy 18 ... | 1987 | 3566354 |
| slow wave changes in amygdala to visual, auditory, and social stimuli following lesions of the inferior temporal cortex in squirrel monkey (saimiri sciureus). | radiotelemetry of slow wave activity of the amygdala was recorded under a variety of conditions. power, and the percentage of power in the delta band, increased in response to stimulation. recordings of monkey vocalizations and slides of ethologically relevant, natural objects produced a greater increase in power than did control stimuli. the responses to auditory stimuli increased when these stimuli were presented in an unrestrained, group setting, yet the responses to the vocalizations remaine ... | 1987 | 3566692 |
| differential effects of inferior temporal cortex lesions upon visual and auditory-evoked potentials in the amygdala of the squirrel monkey (saimiri sciureus). | visual-evoked potentials (veps) and auditory-evoked potentials (aeps) were elicited from amygdala nuclei and inferior temporal (it) cortex in chaired, alert squirrel monkeys to diffuse flash and click stimuli. veps were recorded from electrodes placed in basalis lateralis amygdalae (bla) and basalis medialis amygdalae (bma) while aeps could also be obtained from additional electrode sites in basalis accessorius medialis (bam), centralis amygdalae (cea), and lateralis amygdalae (la). the amygdala ... | 1987 | 3566694 |
| laboratory studies on mansonella marmosetae in the squirrel monkey, saimiri sciureus. | | 1987 | 3572659 |
| spontaneous cryptococcosis of a squirrel monkey (saimiri sciureus) in french guyana. | an old female squirrel monkey (saimiri sciureus) with a tumor-like growth of the lower jaw died in shock after 2 months of illness. histological studies of different tissue samples demonstrated that the pathological agent was cryptococcus. multiple foci of fungus existed in the thoracic cavity with essentially pulmonary and glandular localizations. | 1987 | 3585974 |
| transmission of plasmodium simium to aotus nancymai, a. vociferans, a. azarae boliviensis, and saimiri sciureus boliviensis monkeys. | | 1987 | 3598812 |
| experimental genital trichomoniasis in the squirrel monkey (saimiri sciureus). | the squirrel monkey (saimiri sciureus) has been proposed as a model for urogenital trichomoniasis in man, but has not been accepted as such because of the purported presence of naturally occurring vaginal trichomonads in this animal. the study published here shows that these are easily eradicated organisms of intestinal origin, which eliminates the potential confusion created by them. in addition, our experiments have shown that the hormonal status of primates seems to be a determinant in succes ... | 1987 | 3610164 |
| morphometry and ultrastructure of the squirrel monkey (saimiri sciureus) vestibular nerve. | vestibular nerves of squirrel monkeys (saimiri sciureus) embedded in plastics and epoxies were examined with light microscopy (lm) and transmission electron microscopy (tem), and computerized measures were obtained and analyzed statistically. an average of 12,412 perikarya and 12,005 myelinated nerve fibers was obtained. approximately 0.7% of the perikarya appeared unmyelinated under lm. about 500 unmyelinated fibers were counted. the cross-sectional area of 1,864 perikarya was 200-650 micron 2. ... | 1987 | 3661110 |
| local brainstem glucose utilization in the squirrel monkey. | the 2-deoxy-d-[14c]-glucose method for the measurement of local cerebral glucose utilization (lcgu) in individual brain nuclei and regions has been applied to the squirrel monkey (saimiri sciureus). the determinations were conducted in five conscious, lightly restrained adult, female, colombian squirrel monkeys. local glucose utilization in brainstem structures (lbgu) was highest in nuclei involved in auditory and vestibular functions and in some nuclei involved in general motor activity. the va ... | 1987 | 3664279 |
| animal models of mycoplasma genitalium urogenital infection. | male and female animals were inoculated urogenitally with mycoplasma genitalium, recovered originally from men with nongonococcal urethritis. mice, hamsters and male rhesus monkeys (macaca mulatta) were resistant. male cynomolgus monkeys (macaca fascicularis) were not as sensitive as male chimpanzees (pan troglodytes): 9 of 11 developed an obvious genital tract infection, some shedding organisms for more than 18 weeks. m. genitalium was recovered from the blood of two of them when large numbers ... | 1987 | 3667225 |
| encephalomyocarditis virus infection in african green and squirrel monkeys: comparison of pathologic effects. | this study compared the pathological effects of experimental encephalomyocarditis virus infection in african green monkeys (cercopithecus aethiops) and squirrel monkeys (saimiri sciureus). african green monkeys died within 5 days post-inoculation and significant changes were limited to moderate to severe multifocal nonsuppurative necrotizing myocarditis. squirrel monkeys were less severely affected and died or were euthanized 4 to 41 days post-inoculation. myocardial and central nervous system c ... | 1987 | 3695400 |
| urogenital challenge of primate species with mycoplasma genitalium and characteristics of infection induced in chimpanzees. | eighteen male and eight female primates, representing five subhuman species, were inoculated urogenitally with mycoplasma genitalium, a microorganism recovered from men with nongonococcal urethritis. male rhesus (macaca mulatta) and cynomolgus (macaca fascicularis) monkeys apparently were resistant. female squirrel monkeys (saimiri sciureus) and female tamarins (saguinus mystax) exhibited low-level, genital-tract infections. male chimpanzees (pan troglodytes) developed an obvious genital-tract i ... | 1986 | 3701116 |
| crossed renal ectopia in a squirrel monkey (saimiri sciureus) and an owl monkey (aotus trivirgatus). | a 5-year-old female squirrel monkey, saimiri sciureus, died with a ceco-colonic infarct. an incidental finding was renal ectopia: the left kidney was located between the common iliac arteries posterior to the bifurcation of the aorta and to the right of the body midline. an adult owl monkey, aotus trivirgatus, was killed in renal failure due to end-stage glomerulonephritis. fused kidneys were located on the right side and posterior to the normal position. these are examples of crossed renal ecto ... | 1986 | 3735401 |
| comparative studies of squirrel monkeys (saimiri sciureus) and titi monkeys (callicebus moloch): performance on choice tasks in near space. | squirrel monkeys (saimiri sciureus) and titi monkeys (callicebus moloch) were studied in tasks involving reaching for food in near space (arm's reach). although performance by monkeys of the two species differed in several ways familiar from previous studies, the species did not differ in the tendency to adopt a habitual position or limb during reaching. the findings contrast with previous work on spatial preferences in these species in tasks involving movement of the whole body. together with t ... | 1986 | 3802784 |
| interhemispheric connections in the visual cortex of the squirrel monkey (saimiri sciureus). | the callosal connections within the posterior parietal and occipital cortices were studied in the squirrel monkey with horseradish peroxidase tracing techniques. the data were evaluated with particular emphasis on the relationship of major callosal connections along the 17-18 border. the overall pattern of callosal connections in the squirrel monkey also was compared with callosal patterns in other new world simians. our results show that the dense band of callosal connections along the 17-18 bo ... | 1987 | 3819037 |
| interaction with objects by group-living saimiri sciureus. | we have studied the spontaneous interaction with small, inedible objects by group-living saimiri. twenty-one animals living in a large outdoor enclosure were presented with a set of 10 novel objects of diverse materials, colors, sizes, and shapes. we have used a sampling technique to record the number of monkeys interacting with each object; qualitative observations complemented these measurements. next day the same objects were presented again and the observations continued. this experiment was ... | 1985 | 3837910 |
| induction of protective immunity to plasmodium falciparum in saimiri sciureus monkeys with partially purified exoantigens. | soluble plasmodium falciparum exoantigens in crude culture supernatant fluids induced protective immunity against experimental falciparum malaria in bolivian saimiri sciureus monkeys. susceptible squirrel monkeys were vaccinated with an aluminum hydroxide-fortified fraction purified from culture supernatants of p. falciparum indochina i and geneve/sge-1 by cation-exchange (sulfopropyl-trisacryl) chromatography. animals immunized with sulfopropyl-purified and corresponding control immunogens were ... | 1985 | 3897052 |
| monoclonal antibodies produced against sporozoites of the human parasite plasmodium malariae abolish infectivity of sporozoites of the simian parasite plasmodium brasilianum. | we have used a sporozoite neutralization assay to define the biological relevance of the cross-reactivity of two monoclonal antibodies, raised against sporozoites of the human parasite plasmodium malariae (uganda 1/cdc), with sporozoites of the simian parasite plasmodium brasilianum (colombian). in vitro incubation of each of these two monoclonal antibodies with sporozoites of p. brasilianum totally abolished the infectivity of these parasites for saimiri sciureus. using western blot analysis an ... | 1985 | 3899939 |
| distribution of neuropeptide y immunoreactivity in the basal forebrain and upper brainstem of the squirrel monkey (saimiri sciureus). | the distribution of neuropeptide y (npy) immunoreactivity in the brain of the squirrel monkey (saimiri sciureus) was studied by means of the indirect immunofluorescence, peroxidase-antiperoxidase, and avidin-biotin-complex methods. the antiserum used was raised in rabbits and did not show any significant crossreactivity with related peptides including peptide yy and avian pancreatic polypeptide. in the upper brainstem of the squirrel monkey a dense npy-immunoreactive terminal field is seen in la ... | 1985 | 3902914 |
| colonic mucin composition in primates. selective alterations associated with spontaneous colitis in the cotton-top tamarin. | heterogeneity of colonic mucin glycoprotein was examined in rectal mucosal biopsy specimens from a variety of primate species (saguinus oedipus, n = 18; macaca mulatta, n = 2; macaca fascicularis, n = 2; aotus trivirgatus, n = 2; saimiri sciureus, n = 2; and callithrix jacchus, n = 2). after initial separation of radiolabeled mucin and nonmucin glycoproteins solubilized from mucosal biopsy specimens, at least five labeled mucin components were found in monkey rectal mucosa in contrast to the six ... | 1985 | 3917260 |
| induction of follicular growth in the squirrel monkey (saimiri sciureus) with human urinary follicle-stimulating hormone (metrodin). | human urinary follicle-stimulating hormone (metrodin, serono laboratories, inc., randolph, ma), an investigational drug which is purified from human menopausal gonadotropin (hmg) (pergonal, serono laboratories, inc.), was tested for its effects on induction of follicle development in the squirrel monkey (saimiri sciureus). metrodin was as effective as hmg for induction of follicle development in the squirrel monkey, and it appeared to be superior to hmg or porcine follicle-stimulating hormone at ... | 1985 | 3922805 |
| lipid composition of squirrel monkey (saimiri sciureus) saliva. | the content and composition of lipids in saliva of healthy caries-free squirrel monkeys were investigated. the dialyzed and lyophilized saliva on extraction with chloroform/methanol yielded 8.0 +/- 0.9 mg of lipids/100 ml of saliva. following fractionation on silicic acid column, 30.9% of lipids were found in the neutral lipid fraction, 58.8% in the glycolipid fraction, and 10.3% in the phospholipid fraction. the neutral lipids exhibited high content of free fatty acids (58.8%) and triglycerides ... | 1985 | 3930141 |
| the effect of chamber restraint (with or without lower body positive pressure) on hematopoiesis (particularly erythropoiesis) in squirrel monkeys (saimiri sciureus) | squirrel monkeys, restrained in lower body positive pressure (lbpp) chambers in attempts to model the space flight-induced hematological consequences of a cephalad fluid shift, showed a decrease in red blood cell mass which was largely independent of actual lbpp. the only lbpp-specific hematological effect was an alteration in red blood cell (rbc) survival. this monkey model represents the second, ground-based animal system in which this phenomenon has been recorded and shown to be unique to a c ... | 1986 | 3959062 |
| development of dipetalonema gracile in the squirrel monkey (saimiri sciureus), with notes on its biology. | infective larvae of dipetalonema gracile, which had developed in culicoides hollensis, were inoculated into 4 laboratory-born squirrel monkeys, saimiri sciureus. weekly blood sampling revealed the mean prepatent period to be 297 days. all 4 monkeys developed patent infections in which peak microfilaremias were reached 13 to 18 wk after patency. two laparotomies, performed at 27 and 64 wk, were conducted to evaluate pathological involvement and, at that later time, to recover adult parasites. sli ... | 1985 | 3981344 |
| [2 new filariae of a monkey, saimiri sciureus, in guyana]. | description of two new filariae, parasites of saimiri sciureus l. (georgetown type, karyotype 14/7) from guyana. dipetalonema robini n. sp., fourth species of the genus, is frequent and associated with the morphologically similar species, d. gracile (rud., 1809); d. robini differs from d. gracile by structure of caudal lappets of female, vagina, microfilaria and area rugosa. the second filaria, also frequent, belongs to the subgenus tetrapetalonema which contains a dozen species; mansonella (t.) ... | 1985 | 3985534 |
| chemotherapy of visceral leishmaniasis (leishmania donovani) in the squirrel monkey (saimiri sciureus). | the relationship of the numbers of amastigotes in the liver to the duration of infection with two lines of a khartoum strain of leishmania donovani [designated the parent (p) line and the meglumine antimoniate (glucantime) resistant (mar) line] and the effect of meglumine antimoniate on these two lines of leishmania were studied in the squirrel monkey. all experimental monkeys were inoculated via the saphenous vein with 32.5 x 10(6) amastigotes (per kg body weight), obtained from heavily-infecte ... | 1985 | 3985702 |
| dietary fat unsaturation enhances drug metabolism in cebus but not in squirrel monkeys. | antipyrine disappearance and sleeping time following barbiturate anesthesia were assessed to evaluate the effects of dietary corn oil and coconut oil on the drug-metabolizing enzyme systems (dmes) in cebus (cebus albifrons) and squirrel (saimiri sciureus) monkeys. plasma antipyrine clearance (half-life) was measured in both species before and after induction of dmes by i.v. injection of barbiturates on two consecutive days. sleeping time was measured after administration of either pentobarbital ... | 1985 | 3998859 |
| characterization of gilbert-like syndrome in squirrel monkeys (saimiri sciureus). | bolivian squirrel monkeys, unlike those of brazilian origin, exhibit a marked fasting hyperbilirubinemia (fh) similar to that observed in gilbert's syndrome in man. since no delays in the hepatic clearance of sulfobromophthalein or indocyanine green are present, the bolivian monkey appears to be similar to gilbert's type i syndrome. fh can be significantly decreased by either phenobarbital or tin-protoporphyrin pretreatment. nicotinic acid-induced hyperbilirubinemia and delayed tolbutamide clear ... | 1985 | 3999115 |
| hematologic values of normal bolivian squirrel monkeys (saimiri sciureus): a comparison between wild-caught and laboratory-bred male animals. | complete and differential blood counts were conducted on 23 male squirrel monkeys (saimiri sciureus) of bolivian origin. the sample included 9 laboratory-bred and 14 wild-caught adult monkeys weighing between 600 and 1,500 g. the means of total white blood cell (wbc) counts, total hemoglobin and hematocrits of laboratory-bred animals were found to be significantly different from those of wild-caught monkeys (p less than 0.01). other hematologic parameters showed no significant differences betwee ... | 1985 | 4043872 |
| encephalitozoonosis in squirrel monkeys (saimiri sciureus). | twenty-two cases of naturally occurring encephalitozoonosis in squirrel monkeys are reported from breeding colonies of the delta regional primate research center, covington, la. characteristic foci of granulomatous inflammation and organisms were demonstrated in brains, kidneys, lungs, adrenals, and livers. vasculitis and perivasculitis were also common lesions in several organs. at least seven cases were congenital while ten others occurred in monkeys less than nine months old. granulomatous pl ... | 1985 | 3919491 |
| pentastomid nymph from the brain of a squirrel monkey (saimiri sciureus). i. morphology of the nymph. | a pentastomid nymph of the genus porocephalus was identified following its removal from the brain-meningeal interface of a squirrel monkey, saimiri sciureus. it was characterized by two inner and two outer hooks adjacent to the mouth opening, the presence of accessory lobes (or spines) on the outer hooks, a vertical slit-like mouth opening surrounded by a u-shaped conformation of integument, and annulation of the body surface. stigmata, representing the openings of integumental chloride cells, w ... | 1985 | 4046003 |
| pentastomid nymph from the brain of a squirrel monkey (saimiri sciureus). ii. morphology of the host response. | a porocephalus nymph found in the meninges of a squirrel monkey was encapsulated by connective tissue cells and fibrils presumably derived from the pia mater. the capsule was composed of an inner layer (il) adjacent to the nymphal integument and an outer layer (ol) adherent to the brain surface. separating the two layers was a capsular space. the il was lined by a granular material adjacent to the nymph surface and possessed impressions of annulae and the apical pits of chloride cells. the surfa ... | 1985 | 4046004 |
| terminals of intralaminar thalamic neurons in the pallidum externum of saimiri sciureus. | stereotactic coagulations of intralaminar thalamic nuclei in 6 squirrel monkeys saimiri sciureus produced dark degenerations only of type iv synapses in pallidum externum, according to the classification of hassler and chung often preserving the slightly asymmetric contact and subsynaptic densities. other type iv boutons underwent semidark degeneration, whereas others showed crystalloid degeneration. some of type iv boutons show the deposition of many dense core vesicles and mitochondria with lo ... | 1985 | 4050302 |
| culture of atrial and ventricular cardiac muscle cells from the adult squirrel monkey saimiri sciureus. | atrial and ventricular cardiac muscle cells isolated from the adult squirrel monkey saimiri sciureus were cultured and characterized by light and transmission electron microscopy (tem). freshly isolated cells were striated and cylindrical in shape and, when placed in culture, rounded up and lost their highly organized morphology. with prolonged time in culture, they spread out on the surface of the culture flask and reacquired many of the internal ultrastructural characteristics of their in vivo ... | 1985 | 4054237 |
| leishmania donovani: clinical, hematologic and hepatic changes in squirrel monkeys (saimiri sciureus). | clinical signs, parasite densities, and hematologic and hepatic changes were studied in 7 squirrel monkeys (saimiri sciureus) each of which was inoculated intravenously with amastigotes (5.0 x 10(7) per kg body weight) of a khartoum strain (wr 378) of leishmania donovani. one control monkey was inoculated with uninfected hamster spleen homogenate. five of the infected monkeys recovered spontaneously from visceral leishmaniasis by 8 to 15 wk postinoculation (wk pi) and 2 of the infected monkeys d ... | 1985 | 4057001 |
| distribution of enkephalin-immunoreactive neurons in the forebrain and upper brainstem of the squirrel monkey. | the distribution of enkephalin-immunoreactive neuronal profiles in the forebrain and upper brainstem of the squirrel monkey (saimiri sciureus) was studied by means of the indirect immunofluorescence method. numerous enkephalin-immunoreactive cell bodies and fibers were disclosed in various regions including cerebral cortex, hippocampus, caudate nucleus, putamen, nucleus accumbens, septal area, olfactory tubercle, substantia innominata, amygdala, various hypothalamic and thalamic nuclei, periaque ... | 1985 | 3907752 |
| thermoregulatory adjustments in squirrel monkeys exposed to microwaves at high power densities. | the present study was undertaken to investigate the thermal adjustments of squirrel monkeys exposed in a cold environment to relatively high energy levels of microwave fields. the animals (saimiri sciureus) were equilibrated for 90 min to a cool environment (ta = 20 degrees c) to elevate metabolic heat production (m). they were then exposed for brief (10-min) or long (30-min) periods to 2,450-mhz continuous-wave microwaves. power densities (mpd) were 10, 14, 19, and 25 mw/cm2 during brief exposu ... | 1985 | 3836666 |
| two types of trichromatic squirrel monkey share a pigment in the red-green spectral region. | microspectrophotometric measurements have been obtained for individual photoreceptors from four female squirrel monkeys (saimiri sciureus) that had been shown behaviourally to be trichromatic. relative to a normal human observer, two of the monkeys required more red light for a rayleigh match; the other two required more green light than a normal human observer. in the red-green spectral region, the first type of monkey was found to have two cone pigments with peak sensitivities at approximately ... | 1985 | 3832619 |
| an ultrastructural study of the submandibular glands of the squirrel monkey, saimiri sciureus. | | 1970 | 4097570 |
| experimental protein malnutrition in primates: cytochemical studies on the cerebellum of the squirrel monkey, saimiri sciureus. | | 1973 | 4122806 |
| experimental protein malnutrition in primates. histochemical studies on the dorsal root ganglion cells of healthy and malnourished squirrel monkeys, saimiri sciureus. | | 1973 | 4131706 |
| projections from the striate cortex to the diencephalon in the squirrel monkey (saimiri sciureus). a light microscopic radioautographic study following intracortical injection of h3 leucine. | | 1974 | 4136270 |
| fluorescence histochemistry of monoamine-containing cell bodies in the brain stem of the squirrel monkey (saimiri sciureus). i. the locus caeruleus. | | 1973 | 4196792 |
| homosexual behavior and dominance hierarchy in a group of captive female squirrel monkeys (saimiri sciureus). | | 1973 | 4198058 |
| demodectic mites of subhuman primates i: demodex saimiri sp. n. (acari: demodicidae) from the squirrel monkey, saimiri sciureus. | | 1973 | 4198649 |
| the myoglobin of primates. 4. new world monkeys: cebidae: (1) saimiri sciureus (squirrel monkey); (2) lagothrix lagothricha (humboldt's woolly monkey). callitrichidae: callithrix jacchus (common marmoset). | | 1973 | 4198766 |
| the responses to various stimuli of microfilariae of dirofilaria corynodes, of dipetalonema marmosetae and of unidentified species of filariae in saimiri sciureus and cacajao monkeys. | | 1973 | 4200010 |
| nosematosis in a squirrel monkey (saimiri sciureus). | | 1973 | 4201081 |
| notes on reproduction in captive squirrel monkeys (saimiri sciureus). | | 1973 | 4203261 |
| social preference of the squirrel monkey (saimiri sciureus). | | 1973 | 4204187 |
| letter: pure-tone thresholds of the squirrel monkey (saimiri sciureus). | | 1974 | 4205762 |
| fluorescence histochemistry of monoamine-containing cell bodies in the brain stem of the squirrel monkey (saimiri sciureus). ii. catecholamine-containing groups. | | 1974 | 4205957 |
| fluorescence histochemistry of monoamine-containing cell bodies in the brain stem of the squirrel monkey (saimiri sciureus). 3. serotonin-containing groups. | | 1974 | 4205958 |
| fluorescence histochemistry of monoamine-containing cell bodies in the brain stem of the squirrel monkey (saimiri sciureus). iv. an atlas. | | 1973 | 4206145 |
| visual stimulus control of intracranial self-stimulation in the squirrel monkey (saimiri sciureus). | | 1974 | 4206748 |
| social structure of the squirrel monkey (saimiri sciureus, iquitos): relationships among behavior, heartrate, and physical distance. | | 1973 | 4207776 |
| histochemical localization of acetylcholinesterase enzyme in the 'limbic system' of the brain of the squirrel monkey (saimiri sciureus). | | 1974 | 4208328 |
| chromosome banding patterns in squirrel monkeys (saimiri sciureus). | | 1974 | 4210706 |
| tooth root abscess and fistula in the squirrel monkey (saimiri sciureus). | | 1974 | 4211071 |
| the effect of species-specific vocalization on the discharge of auditory cortical cells in the awake squirrel monkey. (saimiri sciureus). | | 1973 | 4212411 |
| projection of the vestibular nerve to the area 3a arm field in the squirrel monkey (saimiri sciureus). | | 1974 | 4213802 |
| the tonotopic organization of the auditory thalamus of the squirrel monkey (saimiri sciureus). | | 1974 | 4214444 |
| an analysis of subgroup structure and process in a captive squirrel monkey (saimiri sciureus) colony. | | 1974 | 4214738 |
| response variables and motor slow cortical potentials (scp) during performance of learned movements in the squirrel monkey (saimiri sciureus). | | 1974 | 4215987 |
| the prevalence of trypanosomes and microfilariae in panamanian monkeys. | a total of 3,523 wild caught monkeys from panama was examined for blood parasites from august 1968 through june 1972. trypanosomes or microfilariae were observed in the blood of 31.1% of the monkeys. mixed infections, with microfilariae and trypanosomes, were detected in 6.6% of the animals. trypanosoma cruzi was found in marmosets. saguinus geoffroyi (12.2%), in white-faced capuchins, cebus capucinus (5.0%), in squirrel monkeys, saimiri sciureus (1.7%) and in black spider monkeys, ateles fuscic ... | 1974 | 4217567 |
| certain experimentally demonstrated connections of the chief sensory trigeminal nucleus in the squirrel monkey saimiri sciureus. | | 1974 | 4218711 |
| some physiological and behavioural changes associated with oestrus and pregnancy in the squirrel monkey (saimiri sciureus). | | 1974 | 4219846 |
| the hematogram of the squirrel monkey (saimiri sciureus). | | 1966 | 4222124 |
| a technique for the collection of semen from squirrel monkeys (saimiri sciureus) by electro-ejaculation. | | 1967 | 4226759 |