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[the diagnosis of amebic liver abscesses. a study of 107 cases (author's transl)].we have investigated the serum antibodies of 107 patients with extra-intestinal amebiasis and 72 control subjects without demonstrable infection with e. histolytica. it was shown that by means of countercurrent immuno-electrophoresis and indirect hemagglutination scintigraphy and taking into consideration the clinical picture, the diagnosis of extraintestinal amebiasis can be made with the necessary high degree of probability.1979229409
chemotherapeutically active anthraquinones. i. aminoanthraquinones.basically substituted 2,6-diacetaminoanthraquinones proved to have an interesting in vivo effect against entameba histolytica, but this effect was markedly exceeded by that of the series of the 2,6-diamidinoanthraquinones. a number of compounds of this series revealed a significantly stronger extraintestinal effect in the golden hamster than the standard amebicides metronidazole and tinidazole, but they were not superior to these compounds in their trichomonacidal effect, which was in general on ...1979229867
on the pathogenicity of entamoeba histolytica. part i: the role of bacterial associate on the modification of virulence of e. histolytica.of the 3 strains of escherichia coli used, only milner a strain was found capable of modifying the virulence of entamoeba histolytica. none out of twenty-four hamsters inoculated with either 5 x 10(5) of axenically-cultured e. histolytica of nih: 200 strain, or 1 x 10(7) of esch. coli (a, b or c strains), was found to have amebic liver abscess. whereas one out of six hamsters inoculated with the same number of amebae preincubated for 12 hrs with esch. coli of milner a strain was found to have ab ...1979230014
evaluation of enzyme-linked immunosorbent assay for the serodiagnosis of amebiasis.this report describes the development and evaluation of an enzyme-linked immunosorbent assay (elisa) for the detection of antibodies to entamoeba histolytica. highly sensitive and reproducible results were obtained in antigen-coated plates prepared by air-drying at 37 degrees c. comparison of the elisa with indirect fluorescent antibody and indirect hemagglutination techniques showed that the former was slightly more sensitive than the two latter methods. the specificity was evaluated by testing ...1979230200
[effect of host-parasite relations on parasitic pathogenicity]. 1979230655
a clinicopathologic study on patients suffering from "chronic dysentery".fifty adult patients with the self diagnosis of "chronic dysentery" were studied. their faeces were examined microscopically; they were sigmoidoscoped and their rectal mucosa were examined histologically. most of them had irritable bowel syndrome. their sigmoidoscopic appearances were normal and the histology showed only mild increase in the numbers of round cells in the lamina propria. this was regarded as normal for the local population. ten patients showed cysts of entamoeba histolytica in th ...1978230812
[coprologic diagnosis of amebiasis : the rectocolitis cell trap and the value of cultures].the authors give the differential characters of dysenteric amoebae and cells observed in the feaces of patients affected by recto-colitis. in this purpose, they recall the usefullness of cultures for both the presence and the possibility of determination of the amoebae. in short, they deplore the misappreciation of these advantages.1979230914
[synthesis and pharmacological activity of 1,2,3-triazole derivatives of naphthalene, quinoline and pyridine].the preparation of three series of 1,2,3-triazol derivatives, with a naphthalene, quinoline or pyridine ring in 1 position, is described. preliminary pharmacological screening of some of these compounds showed no appreciable activity.1979230987
[association of rectal neoplasm and rectal amebiasis]. 1979231161
revival of pathogenicity of axenically grown entamoeba histolytica for the rat. 1979231423
[amebic fulminating colitis (author's transl)]. 1979231977
the ultrastructure of entamoeba sp. (laredo isolate). observations on thin sections and freeze-fracture preparations. 1979232007
studies on the preservation and enhancement of the virulence of some strains of entamoeba histolytica in axenic and monoxenic cultures. 1979232158
prolonged cultures of entamoeba histolytica. 1979232687
amoebiasis and prostaglandins. 1979233032
interactions between entamoeba histolytica and complement. 1979233113
cell biological analysis of parasite-host cell interactions. ii. cell surface, phagocytosis and virulence of entamoeba histolytica, a review. 1979233565
cryopreservation of parasitic protozoa. 1978233753
mechanism of l-serine oxidation in entamoeba histolytica.1. the enzymatic mechanism of oxygen uptake elicited by l-serine in axenically cultivated trophozoites of entamoeba histolytica was investigated. 2. of 22 amino acids examined, only l-serine stimulated oxygen consumption by intact and disrupted amoebae. 3. pyruvate, a product of serine metabolism, also stimulated oxygen consumption in the amoebae. 4. characterization of the oxygen uptake elicited by both l-serine and pyruvate, and analysis of the products of l-serine metabolism indicate that the ...1979233809
surface properties related to concanavalin a-induced agglutination. a comparative study of several entamoeba strains.pathogenic strains of entamoeba histolytica are more easily agglutinated with concanavalin a (con a) than strains isolated from human asymptomatic carriers. all three pathogenic strains studied here were found to agglutinate with low concentrations of con a in contrast to various nonpathogenic axenic strains of amebas, characterized by their ability to grow at room temperature. our present observations suggest that the extreme susceptibility of pathogenic strains of e. histolytica to agglutinate ...1977233919
ribonuclease activity of entamoeba histolytica.ribonuclease activity of entamoeba histolytica was purified 65-fold by calcium phosphate gel, ammonium sulphate and acetone treatments. the enzyme was inhibited by metal ions, like mg-2+, mn-2+, co-2+ and ca-2+. metal chelating and sulphydryl agents showed no effect. edta and alpha, a'-dipyridyl reversed the inhibition produced by mg-2+, mn-2+ and fe-2+. various sodium salts had negligible effect on the enzyme; however, sodium chloride activated the enzyme slightly. amoebicidal drugs like entero ...1975238352
monoxenic and axenic cultivation of carrier and patient strains of entamoeba histolytica.all of five strains of entamoeba histolytica, isolated from symptomatic cases of amoebiasis, could be adapted to axenic growth on the tp-s-1 medium of diamond (1968). four axenic strains were started from amoeba-crithidia cultures; one could be axenized directly after isolation from a case of cutaneous amoebiasis. attempts to monoxenize, resp. axenize strains, isolated from dutch, asymptomatic carriers, were less successful. only three out of ten strains could be submitted to bacteria-free growt ...1975242136
intestinal and blood parasites in the north lore district, central sulawesi, indonesia.over 1,000 stool specimens from residents of the napu and besoa valleys, central sulawesi, indonesia were examined. schistosoma japonicum was detected in 31% of napu valley residents while in only 2% of the besoa valley residents. hookworm infections were the most frequently encountered helminth parasitisms in both valleys. other helminth parasites encountered were: ascaris lumbricoides, trichuris trichiura, enterobius vermicularis, strongyloides stercoralis, physaloptera sp., diphyllobothrium s ...1977335530
tinidazole and metronidazole in the treatment of intestinal amoebiasis.sixty adult patients with symptomatic intestinal amoebiasis and with entamoeba histolytica present in stools were allocated at random to treatment with tinidazole or metronidazole, both administered in a dose of 2 g once daily for 3 consecutive days. the treatment period was extended in patients with stools positive for entamoeba histolytica on the day following the last treatment day. fifty-six patients, 29 on tinidazole and 27 on metronidazole, completed the trial as per the protocol. twenty-e ...1977340131
chemotherapeutically active nitro compounds. 4.5-nitroimidazoles (part ii).more than 170 1-methyl-5-nitroimidazoles substituted in the 2-position via an aminomethyl, thiomethyl, sulphinylmethyl or sulphonylmethyl group were synthesized and tested for their effect against various protozoa. in the nmri mouse which had been i.p. infected with trichomonas fetus 2 compounds showed an effect superior to that of tinidazole and 31 showed similarly good efficacy as that compound. in comparison with metronidazole 54 preparations proved to be distinctly more active, while 34 othe ...1978350230
aspects of the pharmacology and pharmacokinetics of nitroimidazoles with special reference to tinidazole.tinidazole has been reported to be highly effective against trichomoniasis, giardiasis and amoebiasis. in vitro, tinidazole is more active against trichomonads than metronidazole and possesses antiprotozoal activity at least comparable to metronidazole against entamoeba histolytica, tinidazole gives higher serum levels in animals following oral administration than metronidazole and is well distributed in organs and tissues. when tinidazole or metronidazole is given to healthy volunteers at a dos ...1978350561
treatment of symptomatic intestinal amoebiasis with tinidazole.tinidazole was given in a single dose of 2g a day for 2 days to 17 adults, and in a single dose of 50mg/kg bodyweight daily for 3 days to 4 children, with symptomatic, but not severe, intestinal amoebiasis. all 21 patients showed clinical improvement but only 20 (95%) were parasitologically cured as evinced by failure to demonstrate entamoeba histolytica in 3 stool samples collected on the 4th, 15th and 22nd day after treatment. two subjects had mild nausea within a few hours of taking the first ...1978350562
heat-labile enterotoxigenic escherichia coli and intestinal protozoa in asymptomatic travellers.thirty-two asymptomatic travellers who had recently journeyed in the near, middle, and far east and had experienced a high incidence of diarrhoeal disease were screened for heat-labile enterotoxigenic escherichia coli (ent+ e. coli) and other bacterial and parasitic pathogens. six percent were colonized with ent+ e. coli and while other bacterial pathogens were not found, the intestinal protozoa giardia lamblia (13%), entamoeba histolytica (6%), entamoeba coli (6%), endolimax nana (6%), and enta ...1977351820
serology of amebiasis using the fiax-tm system.a new fluorescent immunoassay system (fiax tm) has permitted development of a promising serologic test for amebiasis. the test is similar but far superior to the soluble antigen fluorescent antibody test. the main differences are the unique stiq tm sampler and the flourometer itself. quantitative results can be obtained from a single standard dilution of serum. the procedure is simple to perform, gives objective readings, and uses the proven principle of immunofluorescence. it is possible to tes ...1978358934
[intestinal amebiasis in children. i. etiological study of colonic lesions of the rectosigmoid colon].a total of 253 children from two months to 12 years old, who had diarrheic or dysenteric syndromes, were studied from the rectosigmoidoscopic and parasitologic points of view. in addition, 112 and 20 of these patients were also studied bacteriologically and virologically, respectively. only in 28 patients torphozoites of entamoeba histolytica were found by means of direct microscopic examination, staining techniques and amoebal cultures. enteropathogenic bacteria were isolated in 41 of the 112 c ...1978358935
human parasitoses of the malili area, south sulawesi (celebes) province, indonesia.a biomedical survey was conducted in 9 villages in the malili area of south sulawesi, indonesia. blood specimens were examined for malaria and microfilariae; stool specimens were examined for intestinal parasites. malaria parasitemias were rare; plasmodium falciparum was detected in 10 and p. vivax in 11 of 985 blood smears. malayan filariasis was endemic to all villages surveyed. the overall prevalence of detectable microfilaremias was 15%, varying from 34% in kawata to 1% in nuha. microfilaria ...1978364674
prevalence of intestinal parasitic infections among inhabitants of tan-nan village, nantou county, taiwan.the pork infected with cysticerci was sent to our laboratory in june 1971. microscopic examination revealed the infection of cysticercus cellulosae. subsequently, the source of the pork was traced, and the survey of intestinal parasitism was carried out among inhabitants at tan-nan village, hsin-i district, nantou county, taiwan, in august 1973. results obtained only indicated the presence rather than endemic of taeniasis solium in this village. the parasites and infection rates found in the pre ...1979397878
electron microscope studies of experimental entamoeba histolytica infection in the guinea pig. iii. histolysis of the cecum. 1977412297
radiology of invasive amebiasis of the colon.entamoeba histolytica is a protozoan that is endemic in various parts of the world, including some areas of the united states. it may live in the large bowel in its cyst form without harming the host (commensalism) or, for as yet poorly understood reasons, invade the tissues as a trophozoite producing invasive amebiasis of the colon. in a review of over 3,000 cases of invasive amebiasis, the clinico-pathologic forms of the disease were: ulcerative rectocolitis (95%), typhloappendicitis (3%), ame ...1977414558
amoebic liver abscess: a retrospective clinical evaluation of twenty-seven cases.twenty-seven patients with amobebic liver abscess were observed during the last two years and were analysed retrospectively with respect to diagnostic procedures and therapeutic strategies. seven of the 27 patients had surgery and were subsequently referred to our hospital. those patients with surgery had a longer duration of illness and hospitalization (3.3 months) compared to the other 20 patients with chemotherapy alone (2 months). most important diagnostic parameters for extraintestinal amoe ...1979538815
[treatment of infections by entamoeba histolytica and giardia lamblia with different dosages of 100 mg tinidazole enteric coated tablets (author's transl)]. 1979540079
[determination of intestinal secretory iga in subjects with acute or chronic apparently healthy intestinal amebiasis and in carriers of entamoeba histolytica]. 1979550730
the prevalence of human intestinal protozoa in ibadan, nigeria.this study shows that the two intestinal protozoa, giardia lamblia, balantidium coli in addition to entamoeba histolytica are prevalent in the ibadan population and are responsible for many of the non-bacterial diarrhoea seen in patients. a high seasonal prevalence of the intestinal protozoa in the dry months of the year was associated with the use of contaminated water. both the high infection rates recorded in adults and children under five years old, and the high frequency of association invo ...1977563477
[chemotherapeutically effective nitro compounds. 3rd communication: nitropyridines, nitroimidazopyridines and related compounds (author's transl)].new 2-nitropyridines and 3-nitropyridines, and 3-nitroimidazo-[1,2-a]-pyridines and related compounds (together 106) were synthesized and tested for their chemotherapeutic efficacy against trichomonads, amoebas and other organisms, such as eimeria tenella, bacteria, fungi, helminths. several 2-nitropyridines revelaed a detectable systemic effect against entamoeba histolytica (extraintestinal amoebiasis of the golden hamster) and also a weak activity against trichomonas fetus in the nmri-mouse. o ...1977576820
age and sex distribution of infections with entamoeba histolytica and giardia intestinalis in the lagos population.stool samples were collected from 2,099 persons and examined for parasites: 9.5 percent were infected with entamoeba histolytica, 7.9 percent were infected with giardia intestinalis and 15.5 percent were infected with iodamoeba butschlii. the infections with e. histolytica and i. butschlii occurred more frequently in females than in males and adults were also more frequently infected than children. infection with g. intestinalis, on the other hand, was more prevalent in males than in females and ...1977591169
parasites of man in remote areas of central and south sulawesi, indonesia.a biomedical survey was conducted in 10 villages in remote, high mountain valleys of central and south sulawesi, indonesia to learn whether oriental schistosomiasis was endemic and to determine the prevalences of other intestinal parasites, malaria and filariasis in those areas. although persons with oriental schistosomiasis were found in three villages of south sulawesi, follow-up inquiries revealed that these had recently migrated from a known schistosomiasis area in central sulawesi. other in ...1977607428
biomedical survey in north samar province, philippine islands.a biomedical survey was carried out in north samar province, philipines to update information on the prevalence of parasitic and other infectious diseases. a total of 1,394 stool specimens, 1,859 blood smears and 1,274 sera were collected from persons living in 8 barrios. stools were examined for intestinal parasites, bloods smears for malaria and filariasis and sera tested for antibodies to schistosoma japonicum, entamoeba histolytica, toxoplasma gondii, influenza a and b, and japanese encephal ...1977614707
amebiasis: epidemiologic studies in the united states, 1971-1974.seven investigations of suspected foci of amebiasis between october 1971 and june 1974 lead to three conclusions. (1) a number of laboratories have vastly overdiagnosed amebiasis and have reported leukocytes in stools as entamoeba histolytica. two laboratories found to be in error were in community hospitals, and one was at a teaching hospital associated with a medical school and a school of public health. these three laboratories had been diagnosing more than 1200 cases of amebiasis a year for ...1978619763
studies on the intestinal parasites in african patients in owamboland, south west africa.the paper gives the results of a survey of intestinal parasites among 501 in-patients drawn from four mission hospitals in owambo and kavango in northern south west africa. most of the patients (90%) were examined twice by the formol-ether concentration method, while the remaining 10% had one stool specimen examined. 10 species of helminths and 3 species of potentially-pathogenic protozoa were recorded--necator americanus, strongyloides stercoralis, strongyloides fuelleborni, hymenolepis nana, t ...1978635971
pleuropulmonary amoebiasis in ghana: a report of three cases.three cases of pleuropulmonary amoebiasis are reported for the first time from ghana. it is suggested that where facilities for identification of the causal agent are not available a therapeutic trial should be given with drugs effective against entamoeba histolytica.1978646939
treatment of intestinal amoebiasis and giardiasis; efficacy of metronidazole and tinidazole compared.aboriginal children who were aged from six to nine years and living in cherbourg community were treated for giardia lamblia and entamoeba histolytica infection with either the manufacturer's recommended dose of metronidazole (flagyl) or with tinidazole (fasigyn), at two-dose levels. tinidazole successfully cleared both protozoans from stools, a single dose being as effective as the longer regimens which were studied. the obvious advantage of single-dose administration is that it should permit mo ...1978672734
[redistribution of surface antigens of entamoeba histolytica and their immunochemical characteristics]. 1978697475
serologic responses in amebiasis.serologic tests for amebiasis, utilizing antigens prepared from entamoeba histolytica hk-9, axenic culture in diamond's media, have demonstrated reproducible results with good clinical correlation. the indirect hemagglutination test was positive in 100 per cent of all cases with hepatic abscess, in 99 per cent of cases of amebic dysentery and in 60 per cent of asymptomatic carriers. a population of uninfected subjects yielded less than 1 per cent of individuals with demonstrable amebic antibodie ...1978697482
[present status of the diagnosis and treatment of invasive amebiasis caused by entamoeba histolytica. i. usefulness of ultrasonography in the diagnosis and evolution of amebic liver abscess]. 1978697485
[present status of the diagnosis and treatment of invasive amebiasis caused by entamoeba histolytica. ii. current status of hepatic scintillography]. 1978697486
[present status of the diagnosis and treatment of invasive amebiasis caused by entamoeba histolytica. iii. medical treatment of amebiasis]. 1978697487
[present status of the diagnosis and treatment of invasive amebiasis caused by entamoeba histolytica. iv. surgical treatment of the complications of invasive amebiasis]. 1978697488
serum ige levels in amoebiasis.elevated levels of serum immunoglobulin e (ige) are found in many parasitic diseases. in order to determine the influence of entamoeba histolytica on ige levels of clinically symptomatic patients with intestinal amoebiasis, a controlled study was performed. there was no difference between the serum ige values from brazilian patients with amoebiasis and those from age-, race- and sex-matched normal brazilian controls. based also on our previous similar studies on giardiasis and chagas' disease, w ...1978709800
surface properties of entamoeba: increased rates of human erythrocyte phagocytosis in pathogenic strains.the assertion that ingestion of human erythrocytes is restricted to invasive strains of entamoeba histolytica has not been evaluated previously by comparative studies. in this report we describe the in vitro ingestion of human erythrocytes by pathogenic and nonpathogenic entamoeba. microscopic evaluation of erythrophagocytosis by eight different entamoeba grown in culture revealed that strains of e. histolytica isolated from cases of human dysentery show a much higher rate of erythrocyte ingesti ...1978722237
cutaneous amebiasis of the eyelid with extension into the orbit.a 4-month-old girl was admitted to hospital with extensive ulceration and erosion of the left eyelid where 17 days earlier the skin had been broken when hit by a ball. despite antibiotic therapy the lesion expanded to involve the orbit. biopsy of the eyelid on the 4th day in hospital, and examination of the eye and attached tissues removed on the 6th, failed to detect amebae until after the infant's death due to a blood transfusion 2 weeks later. re-examination of the tissues revealed abundant a ...1978727318
serological study of amoebiasis and toxoplasmosis in the malili area, south sulawesi, indonesia.results of a serology survey in september 1972 for entamoeba histolytica and toxoplasma gondii antibodies among 915 volunteers from the malili area of south sulawesi (celebes), indonesia are presented. indirect hemagglutination antibody titers for amoebiasis were found in 22.7% of the sampled population while 9.5% demonstrated antibody titers greater than or equal to 1:128. the frequency distribution of antibody titers were similar by sex and age. there was no significant correlation between sto ...1978751213
[medical practice in indians of the colombian amazon. epidemiology of intestinal parasitoses].in spite of the presence of a physician, the real pathology of an indian population of colombie is not very well known. some of ill people are probably entrusted to the traditional "chaman". the western medicine is symptomatic, curative and not preventive. intestinal nematodiasis and amoebiasis are the major problem. prevalences are: ascaris 46%, trichuris 30%, ankylostoma 39%, strongyloides 40%, entamoeba histolytica 30%. among this slowly evoluting population parasitism is related with cultura ...1978754884
parasitic infections in humans in west kalimantan (borneo), indonesia.a survey was carried out among inhabitants of eight villages in west kalimantan province (borneo), whereby blood smears were examined for malaria, stools examined for intestinal parasites and sera tested by the indirect hemagglutination test for antibodies to entamoeba histolytica and toxoplasma gondii. the prevalence of malaria among 3017 people examined was 5.6% (plasmodium vivax 2.8%, plasmodium falciparum 2.8%). brugia malayi microfilariae were found in 3.6% and wuchereria bancrofti in 0.3%. ...1976788263
comparative antigenic analysis of pathogenic and free-living naegleria species by the gel diffusion and immunoelectrophoresis techniques.antigens prepared from each of five strains (ca, cj, hb-1, hb-3, and ty) of pathogenic naegleria and the eg strain of nonpathogenic naegleria gruberi were compared by the gel diffusion and immunoelectrophoresis techniques. axenically grown amoebae were used as sources of antigens. antisera were produced in individual rabbits against three strains (ca, cj, and hb-1) of pathogenic naegleria and the eg strain of n. gruberi. in the gel diffusion experiment each of the six antigens was reacted with e ...1975803926
electron microscope studies of experimental entamoeba histolytica infection in the guinea pig. ii. early cellular and vascular changes accompanying invasion of the lamina propria.early cellular and vascular changes in response to invasion of lamina propria by entamoeba histolytica were studied sequentially, at the ultrastructural level, in germfree guinea pigs inoculated intracecally with amebae and enteric flora derived from patients with acute amebic colitis. approximately one week post-inoculation the animals developed acute colitis with mucosal invasion by trophic amebae. although epithelial cells at the sites of amebic invasion showed progressive cytoplasmic changes ...1976816067
[intestinal amebiasis].infection produced by entamoeba histolytica constitutes a clinical problem of great importance due to its frequence and serious complications. age, diagnosis and clinical manifestations, phisic exploration, lab. procedures, proctosigmoidoscopy, radiology, complications, pathologic anatomy, statistical reports from the ministry of health and social asistence in addition we emphasize on the importance of an accurate and precocious diagnosis. we expose an effective terapeutic regimen for the differ ...1975816701
[the laboratory diagnosis of amoebic infections in man (author's transl)].the rapid progress made in both theoretical and practical fields in laboratory medicine, in general, and in microbiological diagnostic procedures, in particular, have also led to a significant enlargement of, and improvement in laboratory diagnosis of amoebic infections in man. in all intestinal infections with entamoeba histolytica the demonstration of the parasite is absolutely essential, but is facilitated nowadays by the great improvement in technical conditions. immunodiagnostic methods hav ...1977842029
[toxoplasmosis. anatomo clinical characteristics and morphological indentification of the parasite using the silver-impregnation technic].the clinical and anatomicopathological characteristics of acute and chronic toxoplasmosis are described as they affect different structures and systems. the lesion to adrenal glands is compared to that seen in disseminated herpes simplex; however, the question remains as to why in both congenital infections, necrosis of adrenal glands appears without inflammatory reaction. the investigation of special techniques for localization and identification of toxoplasma gondii "groups" or cysts, leads to ...1977843413
plasmalemmal modifications of entamoeba histolytica in vivo.we used electron microscopy to study entamoeba histolytica trophyozoites in rectal and liver lesions. the amebal surface had bleblike structures. also noted were subplasmalemmal vacuoles and plasmalemmal extensions generally similar to the "surface lysosome" and "trigger" previously described. we found on serial sections that the plasmalemmal extensions were dendritic complexes enfolding the membrane of the subplasmalemmal vacuole and extending to contact host tissue. we postulate that membrane- ...1977845740
endemic amebiasis in an extended family.two cousins from a large spanish-american family were simultaneously diagnosed as having amebic liver abscesses. survey of 183 extended-family members revealed that 45.7% of 162 had a positive amebiasis indirect hemagglutination test and 12.6% of 111 had cysts or trophozoites of entamoeba histolytica demonstrated in a single stool examination. a total of five family members had had liver abscesses; two deaths had occurred. in a random sample survey of the remainder of the community, only one per ...1977889003
cellular immune responses to amoebic liver abcess in the guinea-pig.guinea-pigs infected in the liver with the biswas strain of entamoeba histolytica showed no dermal hypersensitivity but showed positive lymphocyte transformation and macrophage-migration inhibition. the time sequence showed an activated response at 4 days after infection, a full response at 8 days when the liver abscesses were resolving and a waning response at 12 days when the abscesses had healed.1977891028
[traveler's diarrhea].travellers' diarrhea afflicts up to 50 percent of tourists in certain geographic regions. it is a syndrome caused by a variety of pathogens, the most common of which is enterotoxigenic e. coli. other responsible pathogens include salmonellae, shigellae, entamoeba histolytica, yersinia enterocolitica, giardia lamblia and virus-like agents, seldom vibrios. symptoms persist for only a few days and are only serious in 1/5 of the cases.1977914154
parasitology survey in northern sumatra, indonesia.a parasitology survey was conducted in five villages in north sumatra, indonesia. a total of 3,207 blood smears, 2,066 stool specimens and 969 sera were examined. sixty (1.9%) inhabitants had malaria (plasmodium vivax 41, p. falciparum 19), and 20 had brugia malayi microfilaraemia. the most common intestinal helminths were trichuris trichiura (87%), ascaris lumbricoides (75%) and hookworm (58%). other helminths found in low numbers were enterobius vermicularis, strongyloides stercoralis, taenia ...1976950682
tinidazole: a review of its antiprotozoal activity and therapeutic efficacy.tinidazole, a synthetic imidazole derivative, has been used in the oral treatment of several protozoal infections - trichomoniasis, giardiasis and amoebiasis. among the protozoal organisms inhibited by tinidazole are trichomonas vaginalis, trichomonas foetus, and entamoeba histolytica. in vitro, tinidazole has been shown to possess antiprotozoal activity at least comparable to, and in some cases greater than, metronidazole. tinidazole also has activity against some gram-negative anaerobic bacill ...1976954609
therapeutic evaluation of oxantel pamoate (1, 4, 5, 6-tetrahydro-1-methyl-2-[trans-3-hydroxystyryl] pyrimidine pamoate) in severe trichuris trichiura infection.the efficacy of oxantel pamoate (1, 4, 5, 6-tetrahydro-2-[trans-3-hydroxystyryl]-1-methyl pyrimidine pamoate) was evaluated in 25 children with severe trichuris infection. the presence of chronic dysentery and sigmoidoscopic demonstration of whipworms in the intestinal mucosa were the criteria for inclusion in the trial. most of these patients had severe anemia, rectal prolapse, digital clubbing, hypoproteinemia, and growth retardation. there were a high incidence of concomitant parasitism with ...1976961973
observations on the intestinal protozoa infecting man in rhodesia.humans in rhodesia harbour a wide range of intestinal protozoa. of the species included, entamoeba histolytica, entamoeba coli and giardia lamblia have previously been recorded. other species which are either rarely reported or which have previously never been reported from this country, include trichomonas hominis, chilomastix mesnili, enteromonas hominis, retortamonas intestinalis, balantidum coli,entamoeba hartmanni,entamoeba histolytica laredo. endolimax nana, dientamoeba fragilis and isospo ...1976988643
action of antiamoebic drugs on ribonuclease and deoxyribonuclease activities of the caeca of rats infected with a virulent strain entamoeba histolytica. 1976992730
heavy trichuris infection and amoebic dysentery in orang asli children. a comparison of the two diseases.children with heavy trichuris infestation were compared with paediatric amoebic dysentery patients and normal children. heavy trichuris infestation was diagnosed by visualization of worms on anoscopy. patients with heavy trichuris infection had a longer duration of disease, more frequent hospitalization and a higher rate of rectal prolapse than did patients with amoebiasis. five trichuris children also had clubbing. trichuris patients had lower mean haematrocrits (27%) and serum albumin (3-3 gm% ...19761006759
parasitological survey in gorontalo north sulawesi, indonesia.a survey for blood and intestinal parasites was carried out in the municipality of gorontalo on the minahasa peninsula of north sulawesi. a total of 156 stool specimens were obtained from 83 males and 73 females. trichuris trichiura, ascaris lumbricoides, hookworm, unidentified dicrocoeliid-like ova and entamoeba coli, in that order, were the most common intestinal parasites detected. other intestinal parasites found less frequently were entamoeba histolytica, iodamoeba bütschlii, endolimax nan ...19761030844
intestinal and blood parasites of man in bireuen and takengon, aceh province, sumatra, indonesia.a survey for blood and intestinal parasites was carried out in aceh province of north sumatra, indonesia. a total of 348 stool specimens were obtained from 167 males and 181 females ranging in age from 6 months to 70 years. over 98% of the population sampled were found infected with at least one intestinal parasite. ascaris lumbricoides, trichuris trichiura, hookworm and entamoeba coli, in that order, were the most common parasites detected. other intestinal parasites found less frequently were ...19761030850
amebic colitis mistaken for inflammatory bowel disease.in ten patients, amebic colitis was mistakenly diagnosed as ulcerative colitis or crohn disease of the colon because of the similarity of history, physical examination, and routine laboratory studies as well as findings on proctoscopic and barium enema examination. multiple stool examinations failed to demonstrate ova or trophozoites of entamoeba histolytica. routine examinations of stools for ova and parasites are inadequate and even a meticulous search for amebas in fresh stool, in scrapings f ...19751052663
entamoeba histolytica in new zealand. 19761067494
massive development of amebas in the large intestine. fedor aleksandrovich lesh (lösch).fedor aleksandrovich lesh (lösch) 1840-1903. although lösch was a distinguished russian physician, little has been written about him in english. a graduate of the medico-chirurgical academy in st. petersburg (1863), he defended a doctoral thesis on pulmonary embolism and infarction in 1866, and became an assistant professor of medicine in 1871. from 1872 to 1885 he was a lecturer on diagnosis at the women's medical college and a consultant to the nikolayev military hospital. in 1885 he became pr ...19751098489
surveillance of some infectious diseases among aircrew personnel in southeast asia.a 2-year analysis of specimens among aircrew personnel in southeast asia is reported. stool specimens were examined for intestinal parasites and enteric bacteria, blood smears for blood parasites, and sera tested for transaminases (sgot) and antibodies to entamoeba histolytica, toxoplasma gondii, chikungunya and japanese encephalitis viruses, rickettsia tsutsugamushi, leptospira sp. and pseudomonas pseudomallei. one to four specimens each were obtained from 537 adult males and 20 females. there ...19751100040
membrane structure and surface coat of entamoeba histolytica. topochemistry and dynamics of the cell surface: cap formation and microexudate.treatment of living entamoeba histolytica cells with low concentrations of concanavalin a (con a) and peroxidase results in redistribution of the plasma membrane con a receptors to one pole of the cell where a morphologically distinct region--the uroid--is formed. capping of con a receptors is not accompanied by parallel accumulation of ruthenium red-stainable components. in capped cells, the pattern of distribution of acidic sites ionized at ph 1.8 (labeled by colloidal iron) at the outer surfa ...19751150744
prevalence of intestinal parasites in latino residents of chicago.in 1970, 250,000 spanish-speaking persons resided in chicago, 80,000 of whom were puerto rican. because migration to chicago is constantly occurring from areas where intestinal parasites are endemic, a survey was conducted in a predominantly puerto rican neighborhood to determine the prevalence of these parasites and to provide impetus for further case finding and treatment programs. the survey was part of an epidemiologic and cutreach workers going door-to-door obtained histories, hematocrits, ...19751202954
intestinal parasites in university of dacca students.nine hundred and thirty three students of dacca university were examined: mean haemoglobin levels were 80.5 per cent for men and 70.0 per cent for women. five hundred and thirty three (57.3%) of the students had single or multiple intestinal parasitic infections, of which ascaris lumbricoides (366), entamoeba histolytica (113) and trichuris trichiura (99) were the commonest. it is suggested that chronic nutritional deficiencies are compounded by these parasites, leading to low weights, and low h ...19751214308
a case of cutaneous amoebiasis.the present report concerns a patient with ulceration around an artificial anus. the condition had been treated for some time as pyoderma gangrenosum but finally proved to be cutaneous amoebiasis; the presence of entamoeba histolytica was demonstrated. a cure was achieved with metronidazol (flagy) and diloxanide furoate (furamide) given orally.19751225662
[chemotherapeutic effects of nitro compounds. 1. nitroanilines].more than 200 nitro compounds, most of them nitroaniline derivatives substituted with one or more radicals having a basic reaction, were prepared and investigated as to their therapeutic activity against bacteria, fungi, protozoa, helminths, viruses and tumors. several mono-nitrobenzenes with a radical having a basic reaction showed weak in-vitro activity against gram-positive bacteria and against crocker's sarcoma 180; they also showed systemic activity against nematodes (aspiculuris tetraptera ...19751242309
treatment of intestinal parasites in australian aboriginal children.five to nine-year-old aboriginal children on mitchell river community maintained a satisfactory growth rate in the presence of multiple infections with intestinal parasites. intensive treatment was successful in eliminating giardia lamblia, entamoeba histolytica, and strongyloides stercoralis infections, but reinfection with g. lamblia was rapid. treatment failed to produce any growth spurt in the group. this may have been due to the rapidity of reinfection, but raises the question of whether in ...19761263912
recognition of entamoeba histolytica lipophosphoglycan by a strain-specific monoclonal antibody and human immune sera.western blot analysis showed that the monoclonal antibody 2d7.10 recognized lipophosphoglycan (lpg) from entamoeba histolytica hm-1:imss. sodium dodecyl sulfate-polyacrylamide gel electrophoresis (sds-page) pattern of [3h]galactose-labeled lpg and western blot analysis of total lysate of e. histolytica with 2d7.10 revealed patterns similar to that of lpg with 2d7.10. this antibody could also immunoprecipitate purified lpg from the strain hm-1:imss after biosynthetically labeling with [3h]galacto ...19921283004
susceptibility of an emetine-resistant mutant of entamoeba histolytica to multiple drugs and to channel blockers.previously a cloned emetine-resistant mutant of the protozoal parasite entamoeba histolytica was shown to overexpress a gene for an ameba homolog of the mammalian p-glycoprotein, a plasma membrane pump that removes hydrophobic drugs from multidrug-resistant tumor cells. three sets of experiments were performed to better characterize the multidrug-resistant phenotype of the emetine-resistant amebae. first, the emetine resistance of the mutant amebae was reversed by concentrations of calcium and s ...19921283295
membrane perforation by entamoeba histolytica: structural implications derived from the sequence of the pore-forming peptide.the pore-forming peptide amebapore is considered crucial for the cytolytic activity of e. histolytica. isolation and subsequent molecular cloning of the peptide allowed predictions as to its secondary structure, most of which were confirmed by experimental data. here, a computer-aided approach is applied to identify, within the peptide, highly amphipathic helical segments predicted to interact with biological membranes. two putative alpha-helices fulfill the criteria of membrane-seeking domains ...19921285083
cloning and partial characterization of an antigen detected on membrane surfaces of non-pathogenic strains of entamoeba histolytica.a novel and unique mab (318-28) which specifically interacts with a 60 kda antigen that is found only on the surfaces of non-pathogenic (np) strains of e. histolytica has been recently characterized. the antigen appears to be present also on (np) cyst forms of amebas but was not detected on any of the various (p)-strains tested. it was also not found on other entamoeba species such as moshkovskii, laredo, huff, coli, gingivalis, or invadens. clinical trails for the differentiation of (p) and (np ...19921285084
sequence and structure of the galactose adherence lectin of entamoeba histolytica. 19921285085
a rapid colorimetric assay with the tetrazolium salt mtt and phenazine methosulfate (pms) for viability of entamoeba histolytica.a rapid colorimetric assay for viability of e. histolytica trophozoites using the tetrazolium salt mtt and phenazine methosulfate (pms) was developed. the mtt is normally reduced by dehydrogenases of viable cells and transformed to formazan, a colored compound; the reaction is catalyzed by pms. trophozoites of e. histolytica were incubated in the presence of mtt and pms during 15, 30, 45, 60 and 75 min, at 37 degrees c. trophozoites killed by heat or cold were used as controls. the formazan prod ...19921285086
structural organization of chromatin during the cell cycle of entamoeba histolytica trophozoites.the nuclear division of e. histolytica trophozoites was analyzed by using specific stains for dna, with the aim to define the sequential changes of chromatin during its life cycle. furthermore, we characterized the internal structural arrangements of microtubules in the microtubular organizing center (mtoc) and determined the number of chromosomes and its association with the spindle. the mtoc is formed by multiple microtubule-nucleating centers, that are involved in the displacement of dna duri ...19921285087
human infections of entamoeba chattoni masquerade as entamoeba histolytica. 19921287923
energy metabolism of ancestral eukaryotes: a hypothesis based on the biochemistry of amitochondriate parasitic protists.parasitic amitochondriate protists, representatives of early branches of eukaryote evolution, differ considerably in their central, energy metabolism from mitochondrion-bearing cells. these differences are: significant metabolic functions of inorganic pyrophosphate, major role of iron-sulfur proteins in key metabolic steps and in hydrogenosome-bearing organisms the disposal of electrons by h2 formation. cytochrome-mediated electron transport and electron transport-linked phosphorylation are abse ...19921292665
pilot studies on the occurrence of some infectious diseases in two different areas in south yemen (aden). part i. parasitology.two pilot studies on malaria, leishmaniasis, schistosomiasis and intestinal parasites were carried out in 104 children 6-15 years old from villages in the lowland and highland areas of south yemen in november 1988. some of the results presented are in the order lowland and highland. the occurrence of malaria parasites in blood smears was 6.7% and 3.8%. p. falciparum was detected only. the antimalarial ifat antibodies were proved in 66.7% and 11.5% respectively. ifat antibodies against leishmania ...19921293209
isolation of entamoeba histolytica from arthritic knee joint.amoebae were isolated from an arthritic knee of a male patient. the organisms grew in egg yolk infusion medium, and in diamond's biosate iron-serum-33 medium, which contained trypanosoma cruzi, and were identified microscopically as entamoeba histolytica. furthermore, amoebae-like organisms in aspirate and cultures were immunocytochemically identified using monoclonal antibodies against e. histolytica. on the basis of the morphologic and immunologic observations, it was concluded that the knee l ...19921295146
[the living and health conditions of palestinian children].young people constitute 46% of the population in the west bank of israel and 48% in the gaza strip with a rate of growth of 3.1% and 3.4%, respectively. their living conditions are characterized by lack of sanitation, shortage of water (especially in comparison to israel proper), unemployment, curfews and closing of schools during tense periods by the military authorities as collective punishment for incidents. since 1967, israel has controlled and administered the health care service in these ...19921296273
inhibition of target cell adhesion by monoclonal antibody to the 66 kd surface antigen of entamoeba histolytica.the adherence of entamoeba histolytica trophozoites to target cells was studied using a monoclonal antibody to a major surface antigen of 66 kd. preincubation of trophozoites with monoclonal antibody decreased their ability to adhere to and engulf erythrocytes and to destroy chinese hamster ovary cells. the monoclonal antibody was specific for the 66 kd antigen, which is possibly a major participant in the adhesion that precedes phagocytosis and cytopathic effects.19921296611
partial purification of acid phosphomonoesterase in axenically grown entamoeba histolytica nih-200.entamoeba histolytica possesses significant acid phosphatase activity as compared to alkaline phosphatase activity. the acid phosphatase activity in the amoebic cells eluted at higher saline concentration as three distinct peaks at 200, 300 and 400 mm sodium chloride.19921296952
colonic immunity in patients and amoebic liver abscess.secretory immunoglobulin a (s-iga), coproantibody titre (antiamoebic) and iga, igg, igm immunocytes in rectal mucosa were studied in 13 patients with amoebic liver abscess (ala) prior to and 4-6 weeks after completion of antiamoebic therapy. ten asymptomatic entamoeba histolytica cyst passers and 17 healthy age and sex matched volunteers served as controls. fecal s-iga levels and counts of iga bearing immunocytes in mucosa were significantly higher in patients with ala and cyst passers as compar ...19921296954
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