| granuloma-specific expression of mycobacterium virulence proteins from the glycine-rich pe-pgrs family. | pathogenic mycobacteria, including the agent of tuberculosis, mycobacterium tuberculosis, must replicate in macrophages for long-term persistence within their niche during chronic infection: organized collections of macrophages and lymphocytes called granulomas. we identified several genes preferentially expressed when mycobacterium marinum, the cause of fish and amphibian tuberculosis, resides in host granulomas and/or macrophages. two were homologs of m. tuberculosis pe/pe-pgrs genes, a family ... | 2000 | 10827956 |
| a finger infection in a pet store employee. | | 1999 | 10414641 |
| identification of mycobacterial dna in cutaneous lesions of sarcoidosis. | sarcoidosis is a multisystemic granulomatous disease of uncertain etiology. recently, mycobacterial dna especially mycobacterium tuberculosis and mycobacterium avium complex were detected in lung tissue and bronchial lavage fluid from patients with sarcoidosis by polymerase chain reaction (pcr) assays in 30% to 50% cases. moreover, cell wall-defective form (cwdf) acid-fast bacteria have been isolated from skin lesions of patients with sarcoidosis which were later confirmed as m. avium complex by ... | 1999 | 10472755 |
| activation of human neutrophils by mycobacterial phenolic glycolipids. | the interaction between mycobacterial phenolic glycolipids (pgls) and phagocytes was studied. human neutrophils were allowed to interact with each of four purified mycobacterial pgls and the neutrophil production of reactive oxygen metabolites was followed kinetically by luminol-/isoluminol-amplified chemiluminescence. the pgls from mycobacterium tuberculosis and mycobacterium kansasii, respectively, were shown to stimulate the production of oxygen metabolites, while pgls from mycobacterium mari ... | 1999 | 10540187 |
| [sporotrichoid mycobacteriosis caused by mycobacterium marinum]. | | 1999 | 10572519 |
| mycobacterium marinum keratitis: pigmentation a clue to diagnosis. | | 1999 | 10624441 |
| [clinical presentation and therapy of mycobacterium marinum infection as seen in 12 cases]. | mycobacterium marinum (m.m.) is the causative pathogen of skin infections that have been called "swimming pool granulomas". an increasing number of reports that deep structures are involved in these infections was the reason for studying the clinical presentation and response of the infection to different therapeutic regimens. | 2000 | 10650818 |
| analysis by enzyme-linked immunosorbent assay and immunoblot of the antibody responses of patients infected with mycobacterium marinum. | the serum antibody responses of a total of 14 patients with active or recently cured mycobacterium marinum infections were analysed via a combination of enzyme-linked immunosorbent assay (elisa) and the immunodevelopment of western blots of m. marinum antigen. normal human sera and sera from patients with active pulmonary tuberculosis were also analysed as controls. the detectable igg response of m. marinum patients, as demonstrated by elisa, was highly variable and did not differ significantly ... | 2000 | 10683462 |
| applications of gene fusions to green fluorescent protein and flow cytometry to the study of bacterial gene expression in host cells. | | 2000 | 11036634 |
| comparative severity of experimentally induced mycobacteriosis in striped bass morone saxatilis and hybrid tilapia oreochromis spp. | twenty striped bass morone saxatilis and 20 hybrid tilapia oreochromis niloticus x o. mossambicus x o. aureus each received a single intramuscular injection of 1.6 x 10(6) colony forming units per gram body weight of mycobacterium marinum. striped bass manifested significantly greater clinical and microscopic disease compared to tilapia. whereas all the striped bass had died or were clinically ill by day 8 post-infection, there was no apparent disruption of normal behaviour, physical appearance, ... | 1999 | 10686670 |
| comparative genetic analysis of mycobacterium ulcerans and mycobacterium marinum reveals evidence of recent divergence. | previous studies of the 16s rrna genes from mycobacterium ulcerans and mycobacterium marinum have suggested a very close genetic relationship between these species (99.6% identity). however, these organisms are phenotypically distinct and cause diseases with very different pathologies. to investigate this apparent paradox, we compared 3,306 nucleotides from the partial sequences of eight housekeeping and structural genes derived from 18 m. ulcerans strains and 22 m. marinum strains. this analysi ... | 2000 | 11053375 |
| a case report of mycobacterium marinum infection of the hand. | we report a case of mycobacterium marinum infection of the hand presenting initially as triggering of the digits. we like to highlight the unusual source of the infection and difficulty of diagnosis in this case as well as the various treatment modalities. | 2000 | 11063172 |
| [aquariums and mycobacterioses]. | mycobacterium infections are increasingly reported in fish fanciers who keep an aquarium. inoculation occurs on abraded skin after an incubation period of 2 to 3 weeks. clinically papulo-nodules, ulcers or verrucous plaques develop. these may progress into sporotrichoid lesions or into deeper infections involving tendons and bone. cultural identification is obtained by biopsy specimen at low temperature (30-33 degrees c). faster identification may be performed by polymerase chain reaction. histo ... | 2000 | 11068476 |
| application of the etest to the antimicrobial susceptibility testing of mycobacterium marinum clinical isolates. | mycobacterium marinum, a well-recognized cutaneous pathogen, is usually treated by chemotherapy without available standardized in vitro susceptibility testing information. in this study, we have attempted to apply the stable-gradient method (etest; ab biodisk, solna, sweden) to susceptibility testing of m. marinum in order to assess the activities of eight antimicrobial agents against 60 recent clinical strains of m. marinum collected from 10 geographic sites within the united states. two plated ... | 1997 | 9230386 |
| [rapidly growing mycobacteria in human pathology]. | | 2000 | 11075485 |
| variable numbers of ttc repeats in mycobacterium leprae dna from leprosy patients and use in strain differentiation. | strain differentiation of mycobacterium leprae would be of great value for epidemiological investigation to identify the infectious sources of leprosy, to understand transmission patterns, and to distinguish between relapse and reinfection. from the m. leprae genome sequence database, ttc dna repeats were identified. primer sets designed to amplify the region flanking ttc repeats revealed pcr products of different sizes, indicating that the number of repeats at each locus may be variable among m ... | 2000 | 11101592 |
| [chronic paronychia and synovialitis of extensor tendons due to mycobacterium marinum. is diagnosis or treatment the problem?]. | most infections of the upper extremity are caused by staphylococcus or streptococcus and respond well to beta-lactam antibiotics. hand surgeons should be aware of the possible diagnosis of mycobacterium marinum infection: 90% of the lesions are found in the upper extremity. we present a case of a chronic, cutaneous lesion of the right middle finger with synovialitis of the extensor tendons observed in a 35-year-old woman. routine cultures from tissue of the infected finger led to the diagnosis o ... | 2000 | 11103693 |
| cutaneous blastomycosis in new brunswick: case report. | blastomycosis is a fungal infection of immunocompetent hosts. we present a case of cutaneous blastomycosis acquired in new brunswick, which provides evidence that this disease is endemic in atlantic canada. this case also demonstrates that the diagnosis of blastomycosis may be elusive. perseverance, a high index of clinical suspicion and close cooperation with the microbiology laboratory may be required to diagnose this uncommon condition. | 2000 | 11107468 |
| [long-standing skin nodular lesions in a 14-year-old male]. | | 1999 | 10687420 |
| direct detection of mycobacterium tuberculosis complex in clinical samples from patients in norway by ligase chain reaction. | our aim was to investigate the use of dna amplification with the ligase chain reaction (lcr) for detection of the mycobacterium tuberculosis complex directly in human clinical specimens. the lcr assay employed was the abbott lcx mtb assay, which uses the gene encoding protein antigen b as the target template. four hundred eighty-two samples from 457 patients in one clinical microbiology laboratory in norway were processed by routine culture analysis (bactec culture), direct microscopy (ziehl-nee ... | 1997 | 9399528 |
| cutaneous infections due to nontuberculous mycobacteria: histopathological review of 28 cases. comparative study between lesions observed in immunosuppressed patients and normal hosts. | to evaluate the histopathological features observed in patients with cutaneous infections due to nontuberculous mycobacteria (ntm) and to compare the histopathological patterns observed in immunosuppressed patients and normal hosts. twenty-eight biopsy specimens corresponding to 27 patients with cutaneous infections due to ntm were reviewed. eighteen biopsies corresponded to normal hosts (14 mycobacterium marinum, 2 mycobacterium chelonae, 1 mycobacterium terrae and 1 mycobacterium gordonae) and ... | 2000 | 10728814 |
| production of a species specific monoclonal antibody against a 56-kda mycobacterium marinum antigen which is potentially useful in culture identification. | a monoclonal antibody (moab) designated 1h11 has been produced against a 56-kda antigen from mycobacterium marinum. this moab has been shown to be species specific by both enzyme-linked immunosorbent assay and western blot. the relationship of this 56 kda to other known mycobacterial antigens is currently under investigation. moab 1h11 recognised bacilli taken from cultures by both immunofluorescence and immunoperoxidase staining. this moab 1h11 may provide a simple method for rapid identificati ... | 2001 | 11172985 |
| sporotrichoid lymphocutaneous infections: etiology, diagnosis and therapy. | sporotrichoid lymphocutaneous infection is an uncommon syndrome that is often misdiagnosed and improperly treated. of the several hundred cases seen each year in the united states, the majority are caused by sporothrix schenckii, nocardia brasiliensis, mycobacterium marinum or leishmania brasiliensis. the "sporotrichoid" disease begins at a site of distal inoculation and leads to the development of nodular lymphangitis. systemic symptoms are characteristically absent. by recognizing the distinct ... | 2001 | 11201697 |
| mycobacterium marinum infection causing septic arthritis and osteomyelitis. | a 48-yr-old female on immunosuppressive therapy for fibrosing alveolitis and polymyositis developed a septic arthritis of the left middle finger proximal interphalangeal joint, tenosynovitis of the left palm and osteomyelitis of the right hindfoot due to infection with mycobacterium marinum. such widespread and severe bone and joint involvement has not been described previously with this organism. | 1997 | 9402866 |
| mycobacterium marinum hand infection. | | 2001 | 11207141 |
| osteomyelitis and tenosynovitis due to mycobacterium marinum in a fish dealer. | osteomyelitis caused by nontuberculous mycobacteria is rarely reported. we describe a case of tenosynovitis and osteomyelitis of the right middle finger and metacarpal bone caused by mycobacterium marinum in a fish dealer. this 52-year-old woman suffered progressive pain, numbness, tenderness, and erythematous swelling of the right middle finger over a 2-month period. a radiograph of the right hand disclosed osteolytic lesions at the third metacarpal bone and the third proximal phalanx. she was ... | 1997 | 9409126 |
| [persistent tuberous plaque in a finger]. | | 1997 | 9411574 |
| mycobacterium marinum infection in a lung transplant recipient. | we report a case of mycobacterium marinum infection in a lung transplant recipient who presented with nodules on the hand and forearm following exposure to fish-tank water of a superficial hand burn. skin biopsy revealed granulomatous inflammation and fibrosis. tissue culture grew mycobacterium marinum. the patient underwent surgical excision of the lesions and treatment with ethambutol and azithromycin for 12 months and experienced complete resolution of the infection. transplant recipients who ... | 2001 | 11295588 |
| a case of disseminated mycobacterium marinum infection following systemic steroid therapy. | we describe the dissemination of mycobacterium marinum infection from the right middle finger to the whole extremity and two legs, with the involvement of tendons and joints, in a patient who was treated with a steroid when mycobacterium marinum infection was not suspected. the patient was successfully treated with a combined surgical and medical approach. | 2001 | 11303818 |
| fish tank granuloma--a frequently misdiagnosed infection of the upper limb. | five patients attended the accident and emergency (a&e) department with fish tank granuloma caused by an infection with mycobacterium marinum. all patients had forearm symptoms which were initially misdiagnosed. they were later recognised by the presence of superficial cutaneous lesions in a sporotrichotic distribution. definitive diagnosis was confirmed by the histological appearances of a biopsy and or culture of the organism. all patients responded to oral minocycline and had uncomplicated re ... | 1997 | 9413782 |
| fish tank granuloma--an unusual cause of skin infection. | | 1997 | 9440925 |
| differentiation of mycobacterium ulcerans, m. marinum, and m. haemophilum: mapping of their relationships to m. tuberculosis by fatty acid profile analysis, dna-dna hybridization, and 16s rrna gene sequence analysis. | although mycobacterium ulcerans, m. marinum, and m. haemophilum are closely related, their exact taxonomic placements have not been determined. we performed gas chromatography of fatty acids and alcohols, as well as dna-dna hybridization and 16s rrna gene sequence analysis, to clarify their relationships to each other and to m. tuberculosis. m. ulcerans and m. marinum were most closely related to one another, and each displayed very strong genetic affinities to m. tuberculosis; they are actually ... | 1998 | 9542909 |
| the use of is2404 restriction fragment length polymorphisms suggests the diversity of mycobacterium ulcerans from different geographical areas. | buruli ulcer, caused by mycobacterium ulcerans, has been reported in five continents: africa, asia, australia, and north and south america. in the present study, restriction fragment length polymorphism with the recently described m. ulcerans specific insertion sequence is2404 as a probe, was applied to mycobacterium shinshuense, mycobacterium marinum, and 14 clinical m. ulcerans isolates originating from six geographic areas: africa (n = 6), australia (n = 2), mexico (n = 1), south asia (n = 2) ... | 2001 | 11463115 |
| goldfish, carassius auratus, a novel animal model for the study of mycobacterium marinum pathogenesis. | we have developed an animal model for studying mycobacterial pathogenesis using mycobacterium marinum and the goldfish, carassius auratus. goldfish are injected intraperitoneally with doses between 10(2) and 10(9) cfu of m. marinum organisms. depending on the dose of m. marinum organisms administered, an acute or chronic disease is produced. the acute disease is characterized by systemic mycobacterial infection, severe peritonitis, tissue necrosis, and a short median survival time. the chronic d ... | 1998 | 9596770 |
| oxidative stress response and characterization of the oxyr-ahpc and fura-katg loci in mycobacterium marinum. | oxidative stress response in pathogenic mycobacteria is believed to be of significance for host-pathogen interactions at various stages of infection. it also plays a role in determining the intrinsic susceptibility to isoniazid in mycobacterial species. in this work, we characterized the oxyr-ahpc and fura-katg loci in the nontuberculous pathogen mycobacterium marinum. in contrast to mycobacterium smegmatis and like mycobacterium tuberculosis and mycobacterium leprae, m. marinum was shown to pos ... | 1998 | 9733688 |
| production of selenomethionine-labelled proteins using simplified culture conditions and generally applicable host/vector systems. | the amino acid analogue selenomethionine (semet) is shown to be efficiently incorporated into recombinant proteins expressed in escherichia coli grown in a simple minimal medium without the addition of synthetic amino acids. furthermore, satisfactory semet incorporation is obtained with a methionine-prototrophic strain transformed with commonly used vector systems. as examples, purified tryparedoxin 1 from crithidia fasciculata, alkylhydroperoxide reductase (ahpc) from mycobacterium marinum and ... | 2001 | 11601620 |
| the identification of mycobacterium marinum genes differentially expressed in macrophage phagosomes using promoter fusions to green fluorescent protein. | mycobacterium marinum, like mycobacterium tuberculosis, is a slow-growing pathogenic mycobacteria that is able to survive and replicate in macrophages. using the promoter-capture vector pfpv27, we have constructed a library of 200-1000 bp fragments of m. marinum genomic dna inserted upstream of a promoterless green fluorescent protein (gfp) gene. only those plasmids that contain an active promoter will express gfp. macrophages were infected with this fusion library, and phagosomes containing flu ... | 1998 | 9767585 |
| an unusual case of flexor sheath tenosynovitis. | we report a case of a flexor sheath tenosynovitis caused by mycobacterium marinum. | 1998 | 9821624 |
| atypical hand infections. | the diagnosis and treatment of an atypical hand infection present a distinctive challenge for the hand surgeon. infections caused by these uncommon organisms occur more often in immunocompromised patients. this article emphasizes the salient features of mycobacterial, nocardial, and fungal infections of the hand. with an accurate and timely diagnosis, appropriate surgical and pharmacologic treatment may eradicate these unusual infections. | 1998 | 9884899 |
| mycobacterium marinum dermatitis and panniculitis with chronic pleuritis in a captive white whale (delphinapterus leucas) with aortic rupture. | a 16-year-old female white whale, delphinapterus leucas, died after nearly 18 months of chronic lymphopenia and pyogranulomatous dermatitis. necropsy revealed rupture of the aorta with hemorrhage into the cranial mediastinum and between fascial planes of the ventral neck musculature. multiple foci of ulcerative dermatitis and panniculitis were present across the thorax and abdomen and surrounded the genital folds. in addition, there was a chronic proliferative pleuritis with over 20 liters of hi ... | 2001 | 11724146 |
| a unique mycobacterium species isolated from an epizootic of striped bass (morone saxatilis). | we isolated a mycobacterium sp. resembling mycobacterium marinum and m. ulcerans from diseased striped bass (morone saxatilis) during an epizootic of mycobacteriosis in the chesapeake bay. this isolate may represent an undescribed mycobacterium species, based on phenotypic characteristics and comparative 16s rrna gene sequence. | 2001 | 11747708 |
| health and safety concerns in fisheries and aquaculture. | only 10% of all foodborne illnesses in the united states are attributed to seafood, making seafood a relatively safe food commodity. the implementation of hazard analysis and critical control points guidelines should make seafood consumption even safer. concerns include closed-loop, indoor, water-recirculating production systems; harmful algal blooms in marine environments, which can cause paralytic, neurologic, amnesic, and diarrhetic shellfish poisonings and ciguatera fish poisoning; bacteria ... | 1999 | 10329911 |
| retrospective study of mycobacterium marinum skin infections. | although infection by mycobacterium marinum is well reported in the literature, there have been few epidemiologic studies. the purpose of this study was to review the epidemiology of patients with cutaneous m. marinum infection over a 3-year period at the national skin centre in singapore. | 2000 | 10849123 |
| [sporotrichoid infection with mycobacterium marinum: successful therapy with oral tetracycline administration]. | atypical mycobacterial infections of the skin present a diagnostic and therapeutic challenge to dermatologists in many instances. we report on a patient who was diagnosed with atypical mycobacteriosis in its rarer, sporotrichoid form. possible differential diagnoses are discussed. efficient therapy using minocycline is demonstrated. | 2000 | 10875074 |
| mycobacterium marinum hand infection: case reports and review of literature. | three patients with mycobacterium marinum infection are described. key elements in the diagnosis of this infection are a high index of suspicion, taking a history with an emphasis on exposure to tropical fish or other potential sources of m. marinum infection, and tissue biopsy for culture and histology. the microbiologist should be informed about the suspicion of m. marinum infection so that appropriate cultures can be performed. as m. marinum does not grow under routine culture conditions, the ... | 2000 | 10878841 |
| incubation period and sources of exposure for cutaneous mycobacterium marinum infection: case report and review of the literature. | the diagnosis of cutaneous mycobacterium marinum infection is often delayed for months after presentation, perhaps because important clinical clues in the patient's history are frequently overlooked. knowledge of the incubation period allows the clinician to target questions about the patient's history. prompted by a case with a prolonged incubation period, we sought to determine more precisely the incubation period of m. marinum infection. the medline database for the period 1966-1996 was searc ... | 2000 | 10987702 |
| susceptibilities of mycobacterium marinum to gatifloxacin, gemifloxacin, levofloxacin, linezolid, moxifloxacin, telithromycin, and quinupristin-dalfopristin (synercid) compared to its susceptibilities to reference macrolides and quinolones. | the susceptibility pattern of mycobacterium marinum was determined. quinupristin-dalfopristin and telithromycin were less active than clarithromycin. linezolid showed good antimicrobial activity at clinically achievable concentrations. gatifloxacin, levofloxacin, and moxifloxacin displayed activities similar to those of ciprofloxacin. gemifloxacin was less active. the etest method showed variable agreement with the reference method. | 2002 | 11897601 |
| [skin nodules and ulcers of the limbs in a patient with rheumatoid arthritis]. | while being treated with corticosteroids and methotrexate for rheumatoid arthritis, a 63-year-old man developed livid nodules on his lower arms, hands and feet, as well as fever, necrotizing skin ulcers and rupture of a finger extensor tendon. | 2002 | 11935470 |
| mycobacterium marinum infection in taiwan. | mycobacterium marinum often causes skin infections, tenosynovitis, arthritis, and osteomyelitis, and occasionally results in severe disseminated infections in immunocompromised patients. in this study, the clinical features of 14 cases of m. marinum infection were retrospectively analyzed. one patient had septic arthritis, the other 13 had skin infections and/or tenosynovitis. it usually took 2 months or longer for a definite diagnosis to be made in these patients. three of the 14 patients were ... | 2002 | 11950119 |
| case report--slowly enlarging mass of the dorsal right hand in a pregnant woman. | | 2001 | 11965202 |
| [cutaneous nodular infection with hemopathy]. | a 36-year-old man with treated hairy cell leukemia developed a skin infection due to mycobacterium marinum. a spectrum of atypical cutaneous mycobacteriosis presentations with immunosuppression can be found. the recognition of the disease needs cutaneous biopsies for histopathology and its identification by specific laboratory methods to adapt treatment. | 2000 | 11015652 |
| pulmonary mycobacteriosis caused by mycobacterium haemophilum and m. marinum in a royal python. | an adult female royal python was referred with an 18-month history of chronic respiratory tract disease. anemia and moderate leukocytosis with heterophilia and monocytosis were detected and interpreted as evidence of a chronic inflammatory condition. evaluation of lateral and dorsoventral radiographic views revealed multiple soft-tissue opacities within the cranial lung fields. endoscopic evaluation revealed that the normal reticulated pattern on the surface of the lung had been largely replaced ... | 2002 | 12051506 |
| antibiotic susceptibility pattern of mycobacterium marinum. | in vitro activities of 17 antibiotics against 53 clinical strains of mycobacterium marinum, an atypical mycobacterium responsible for cutaneous infections, were determined using the reference agar dilution method. rifampin and rifabutin were the most active drugs (mics at which 90% of the isolates tested were inhibited [mic(90)s], 0.5 and 0.6 microgram/ml, respectively). mics of minocycline (mic(90), 4 microgram/ml), doxycycline (mic(90), 16 microgram/ml), clarithromycin (mic(90), 4 microgram/ml ... | 2000 | 11036036 |
| diverse bacteria are pathogens of caenorhabditis elegans. | practically and ethically attractive as model systems, invertebrate organisms are increasingly recognized as relevant for the study of bacterial pathogenesis. we show here that the nematode caenorhabditis elegans is susceptible to a surprisingly broad range of bacteria and may constitute a useful model for the study of both pathogens and symbionts. | 2002 | 12117988 |
| skin disease and nontuberculous atypical mycobacteria. | | 2000 | 11044189 |
| susceptibility testing for mycobacteria. | mycobacterial susceptibility testing is important for the management of patients with tuberculosis and those with disease caused by certain nontuberculous mycobacteria. to help standardize methods used in the clinical microbiology laboratory for testing susceptibility of mycobacteria, the national committee for clinical laboratory standards (nccls) recently updated nccls document m24-t (published in 1995), which is the tentative standard for antimycobacterial susceptibility testing of mycobacter ... | 2000 | 11073754 |
| persistent ulcers on the hand of an aquarium owner. | we present a patient with skin ulcers that did not respond to a 3-week course of treatment with amoxicillin-clavulanic acid. as the patient maintained a fish aquarium, mycobacterial infection was suspected. indeed, reassessment of histopathology revealed acid-fast bacilli, and mycobacterial cultures at 30 degrees c grew mycobacterium marinum. eventually, surgical reconstruction of the tendons was needed. | 2002 | 12238586 |
| mechanism of photoinduced carotenoid synthesis. induction of carotenoid synthesis by antimycin a in the absence of light in mycobacterium marinum. | | 1967 | 12325382 |
| topically acquired bacterial zoonoses from fish: a review. | the main pathogens acquired topically from fish (through spine puncture or open wounds) are aeromonas hydrophila, edwardsiella tarda, erysipelothrix rhusiopathiae, mycobacterium marinum, streptococcus iniae, vibrio vulnificus and vibrio damsela. s. iniae has recently emerged as a public health hazard associated with aquaculture, and m. marinum often infects home aquarium hobbyists. with the expansion of aquaculture and popularity of recreational fishing in australia, medical practitioners can ex ... | 2000 | 11130351 |
| strain variation in mycobacterium marinum fish isolates. | a molecular characterization of two mycobacterium marinum genes, 16s rrna and hsp65, was carried out with a total of 21 isolates from various species of fish from both marine and freshwater environments of israel, europe, and the far east. the nucleotide sequences of both genes revealed that all m. marinum isolates from fish in israel belonged to two different strains, one infecting marine (cultured and wild) fish and the other infecting freshwater (cultured) fish. a restriction enzyme map based ... | 2002 | 12406715 |
| biofilm formation and biocide susceptibility testing of mycobacterium fortuitum and mycobacterium marinum. | the ability of non-tuberculous mycobacteria to form biofilms may allow for their increased resistance to currently used biocides in medical and industrial settings. this study examines the biofilm growth of mycobacterium fortuitum and mycobacterium marinum, using the mbec trade mark assay system, and compares the susceptibility of planktonic and biofilm cells to commercially available biocides. with scanning electron microscopy, both m. fortuitum and m. marinum form biofilms that are morphologic ... | 2003 | 12432460 |
| [mycobacterium marinum nodular lymphangitis]. | mycobacterium marinum has been recognized for some forty years. it generally occurs after trauma in a patient who manipulates tropical fish living in an aquarium. | 2000 | 11147048 |
| detection of a new mycobacterium species in wild striped bass in the chesapeake bay. | investigation into recent declines in striped bass health in the chesapeake bay in maryland resulted in the isolation of a putative new species of mycobacterium. this isolate was obtained from fish showing skin ulcers and internal granulomas in various organs. the isolate was slow growing at 28 degrees c; was nonchromogenic; showed no activities of nitrate reduction, catalase activity, tween 80 hydrolysis, tellurite reduction, or arylsulfatase reduction; grew best at low salt concentrations; and ... | 2001 | 11158132 |
| activation of cutaneous sarcoidosis following mycobacterium marinum infection of skin. | sarcoidosis has long been associated with mycobacterial infection, especially with mycobacterium tuberculosis, although a causal association has not been proven. atypical mycobacteria have also been implicated in causing sarcoidosis, but there is as yet no conclusive evidence. we report the activation of cutaneous sarcoidosis following infection with m. marinum, raising further questions about the role of these bacteria in causing this chronic granulomatous disorder. | 2000 | 11204520 |
| multicenter study of incidence of mycobacterium marinum in humans in spain. | a retrospective survey was carried out on the epidemiological monitoring of the isolation incidence of mycobacterium marinum in 21 laboratories, in an attempt to gain an insight into the frequency of its isolation in spain. from 1991 to 1998, 39 cases (22 male and 17 female) of bacteriologically confirmed m. marinum infection were accumulated. the majority of the cases (35) were fish related. the clinical presentation usually suggested sporotrichosis, with the majority of skin eruptions appearin ... | 2001 | 11258515 |
| mycobacterial infection in farmed turbot scophthalmus maximus. | mycobacteriosis (piscine tuberculosis) has been reported to affect a wide range of freshwater and marine fish species; however, this is the first report describing mycobacterial infections in turbot scophthalmus maximus. high numbers of granulomas were initially observed in the organs of moribund farmed turbot. bacteriological analysis of organs with granulomas led to the isolation of mycobacterium marinum. further analysis, to determine the prevalence of the infection in the farm and to identif ... | 2002 | 12517009 |
| [mycobacterium marinum infection]. | | 2002 | 12522903 |
| new clues to how the tb bacillus persists. | | 2000 | 10847835 |
| transposon mutagenesis of mycobacterium marinum identifies a locus linking pigmentation and intracellular survival. | pathogenic mycobacteria survive and replicate within host macrophages, but the molecular mechanisms involved in this necessary step in the pathogenesis of infection are not completely understood. mycobacterium marinum has recently been used as a model for aspects of the pathogenesis of tuberculosis because of its close genetic relationship to mycobacterium tuberculosis and because of similarities in the pathology and course of infection caused by this organism in its natural hosts, fish and frog ... | 2003 | 12540574 |
| nostril infection due to mycobacterium marinum in an immunocompetent host. | mycobacterium marinum infection developed in the nostril of an immunocompetent host whose only risk factors were infrequent swimming and cleaning of a small fish bowl on a single occasion. the lesion relapsed after 2 surgical excisions but resolved slowly with a 9-month course of trimethoprim/sulfa therapy. | 2002 | 12587630 |
| transposition of tn5367 in mycobacterium marinum, using a conditionally recombinant mycobacteriophage. | mycobacterium marinum is a close relative of the obligate human pathogen mycobacterium tuberculosis. as with m. tuberculosis, m. marinum causes intracellular infection of poikilothermic vertebrates and skin infection in humans. it is considered a valid model organism for the study of intracellular pathogenesis of mycobacteria. low transformation efficiencies for this species have precluded approaches using mutant libraries in pathogenesis studies. we have adapted the conditionally replicating my ... | 2003 | 12591896 |
| [treatment resistant nodules in the arm of an officer]. | | 2003 | 12607475 |
| ill from eel? | | 2003 | 12614734 |
| mycobacterium marinum osteomyelitis. | | 2003 | 12650330 |
| mycobacterial infections in domestic and wild animals due to mycobacterium marinum, m. fortuitum, m. chelonae, m. porcinum, m. farcinogenes, m. smegmatis, m. scrofulaceum, m. xenopi, m. kansasii, m. simiae and m. genavense. | the epidemiology and the natural distribution of mycobacterium marinum, m. fortuitum, m. chelonae, m. porcinum, m. farcinogenes, m. smegmatis, m. scrofulaceum, m. xenopi, m. kansasii, m. simiae and m. genavense are described. in addition to the bacteriological, biochemical and genetic characteristics, the authors review the pathology of these species, including the natural and experimental diseases and the accompanying lesions, diagnosis, antibiotic sensitivities and treatment of animal infectio ... | 2001 | 11288516 |
| in vitro activity of linezolid against slowly growing nontuberculous mycobacteria. | mics of linezolid in broth microdilutions were tested against 341 slowly growing nontuberculous mycobacteria (ntm) belonging to 15 species. the proposed linezolid susceptibility mics for all mycobacterium marinum, mycobacterium szulgai, mycobacterium kansasii, mycobacterium malmoense, and mycobacterium xenopi isolates and for 90% of mycobacterium gordonae and mycobacterium triplex isolates were </=8 micro g/ml. linezolid has excellent therapeutic potential against most species of ntm. | 2003 | 12709349 |
| unusual and memorable. a tender swelling of the dorsum of a hand in a middle aged woman. | | 2001 | 11350842 |
| sporotrichoid lymphangitis due to group a streptococcus. | we describe what is, to our knowledge, the first case of sporotrichoid lymphangitis caused solely by group a streptococcus in an otherwise healthy patient. infection with pyogenic pathogens, such as streptococci and staphylococci, as well as with the most common causes of sporotrichoid lymphangitis (i.e., sporothrix schenkii, nocardia brasiliensis, mycobacterium marinum, and leishmania species) should be considered in differential diagnosis for some patients. | 2001 | 11360227 |
| drosophila melanogaster is a genetically tractable model host for mycobacterium marinum. | mycobacterium marinum is a pathogenic mycobacterial species that is closely related to mycobacterium tuberculosis and causes tuberculosis-like disease in fish and frogs. we infected the fruit fly drosophila melanogaster with m. marinum. this bacterium caused a lethal infection in the fly, with a 50% lethal dose (ld(50)) of 5 cfu. death was accompanied by widespread tissue damage. m. marinum initially proliferated inside the phagocytes of the fly; later in infection, bacteria were found both insi ... | 2003 | 12761139 |
| intracellular replication of mycobacterium marinum within dictyostelium discoideum: efficient replication in the absence of host coronin. | mycobacterium marinum causes tuberculosis-like disease in fish and amphibians and has been used as a model mycobacterial species because of its rapid growth and less stringent containment requirements relative to other mycobacterial species. we demonstrate here that m. marinum grows within dictyostelium discoideum cells, allowing the genetic analysis of host factors that may modulate the replication of mycobacterial species. intracellular growth of m. marinum was shown to mimic the properties pr ... | 2003 | 12761143 |
| identification of mycobacterium marinum in sea-urchin granulomas. | sea-urchin granuloma is a chronic granulomatous reaction arising after injury with sea-urchin spines. classified as an allergic foreign-body type of granuloma, it is believed to be a delayed-type reaction to an as yet unidentified antigen. in a clinicopathological study, 50 biopsy specimens from 35 patients diagnosed as having sea-urchin granuloma caused by paracentrotus lividus, we found different inflammatory patterns that in some cases suggested a mycobacterial infection. | 2001 | 11453918 |
| antimicrobial susceptibility of mycobacterium marinum determined by e-test and agar dilution. | mycobacterium marinum is recognized as a cutaneous pathogen requiring antibiotic treatment. we compared the e-test with a reference agar dilution method for susceptibility testing of m. marinum to amikacin, ciprofloxacin, clarithromycin, doxycycline, rifampicin, trimethoprim-sulfamethoxazole and ethambutol. mics obtained after 6 d showed agreement between the e-test and agar dilution within +/- 2 dilutions in 95% of all cases for amikacin, ciprofloxacin, doxycycline and rifampicin. inhibitory co ... | 2001 | 11525351 |
| [lymphocutaneous syndrome due to mycobacterium marinum in a young aquarium enthusiast]. | | 2001 | 11844463 |
| decolorization of malachite green and crystal violet by waterborne pathogenic mycobacteria. | mycobacterium avium, mycobacterium intracellulare, mycobacterium scrofulaceum, mycobacterium marinum, and mycobacterium chelonae tolerate high concentrations of the dyes malachite green and crystal violet. cells of strains of those species decolorized (reduced) both malachite green and crystal violet. because decolorized malachite green lacked antimicrobial activity, the resistance of these mycobacteria could be due, in part, to their ability to decolorize the dyes. small amounts of malachite gr ... | 2003 | 12821489 |
| [tropical fish salesmen's knowledge and behaviour concerning "fish tank granuloma"]. | mycobacterium marinum is responsible for "fish tank granuloma", a chronic and sometimes disabling skin infection, which in france would be the most frequent "atypical" cutaneous mycobacteriosis. tropical fish salesmen are concerned about this disease because they might sell contaminated fish and be infected themselves. a review of the literature indicated that one quarter of the patients were aquarium workers. this original study tested the salesmen's knowledge and behaviour regarding "fish tank ... | 2003 | 12843853 |
| in vitro activity of 11 antimicrobial agents, including gatifloxacin and gar936, tested against clinical isolates of mycobacterium marinum. | in vitro activities of 11 antimicrobial agents were determined using etest (ab biodisk, solna, sweden) against 37 clinical isolates of mycobacterium marinum. the most potent agent (mic(50,) 0.047 microg/ml) was trimethoprim/sulfamethoxazole, but only 91.9% would be categorized as susceptible. several agents had a complete spectrum of activity including gatifloxacin (mic(90,) 0.38 microg/ml), minocycline (mic(90,) 2 microg/ml), tetracycline (mic(90,) 2 microg/ml) and amikacin (mic(90,) 3 microg/m ... | 2002 | 11858912 |
| [granulomatous skin disease after an exotic injury]. | piranhas are feared freshwater fishes commonly found in the waters of southern venezuela to the north of argentina. at present this species is a favourite domesticated article of our aquarists. the authors describe the histopathologic picture of a cutaneous lesion of the right hand thumb of a 60-year old piranha keeper who was bitten by this predatory fish. a firm node with increasing soreness gradually developed in the area of the lesion, and after 7 months the symptoms of the carpal tunnel syn ... | 2003 | 12874906 |
| complex pattern of mycobacterium marinum gene expression during long-term granulomatous infection. | during latent infection of humans with mycobacterium tuberculosis, bacteria persist in the asymptomatic host within granulomas, organized collections of differentiated macrophages, and other immune cells. the mechanisms for persistence remain poorly understood, as is the metabolic and replicative state of the microbes within granulomas. we analyzed the gene expression profile of mycobacterium marinum, the cause of fish and amphibian tuberculosis, during its persistence in granulomas. we identifi ... | 2002 | 11891270 |
| [nontuberculous mycobacterial infections]. | | 2001 | 11977501 |
| [pulmonary mycobacterioses--frequency of occurrence, clinical spectrum and predisposing factors]. | various types of non-tuberculous mycobacteria can be the aetiologic factors of chronic lung infections especially in patients with underlying chronic lung diseases. the aim of this study is to present the cases of pulmonary mycobacterioses observed in institute of tuberculosis and lung diseases in the years 1995-2001. there were 23 patients, 12 men and 11 women in the age between 35-77 years, mean 56 years. 16 out of 23 patients had underlying respiratory problems, mainly healed tuberculosis (7) ... | 2002 | 12884564 |
| mycobacteriosis in two captive florida manatees (trichechus manatus latirostris). | two male florida manatees (trichechus manatus latirostris) died at the marine aquarium in inagi city, tokyo, japan. acid-fast bacteria were demonstrated in tuberculoid nodules in the lungs from both manatees. mycobacterium marinum and m. fortuitum were isolated from one manatee; m. marinum and m. kansasii were cultured from the second animal. this report confirms the pathogenicity and potentially fatal outcome of mycobacterial infection in manatees. in addition, the pathologic response to infect ... | 2003 | 12885137 |
| requirement for kasb in mycobacterium mycolic acid biosynthesis, cell wall impermeability and intracellular survival: implications for therapy. | mycobacterium tuberculosis infects one-third of the world's population and causes two million deaths annually. the unusually low permeability of its cell wall contributes to the ability of m. tuberculosis to grow within host macrophages, a property required for pathogenesis of infection. mycobacterium marinum is an established model for discovering genes involved in mycobacterial infection. mycobacterium marinum mutants with transposon insertions in the beta-ketoacyl-acyl carrier protein synthas ... | 2003 | 12950920 |
| characterization of an unusual mycobacterium: a possible missing link between mycobacterium marinum and mycobacterium ulcerans. | in an attempt to characterize an unusual mycobacterial isolate from a 44-year-old patient living in france, we applied phenotypic characterizations and various previously described molecular methods for the taxonomic classification of mycobacteria. the results of the investigations were compared to those obtained in a previous study with a set of temporally and geographically diverse mycobacterium ulcerans (n = 29) and mycobacterium marinum (n = 29) isolates (k. chemlal, g. huys, p.-a. fonteyne, ... | 2002 | 12089250 |
| sixty-three cases of mycobacterium marinum infection: clinical features, treatment, and antibiotic susceptibility of causative isolates. | mycobacterium marinum is a nontuberculous mycobacterium responsible for skin infections. although cases have been seldom reported, no series of m marinum infection has been recently reported and the treatment is not standardized. | 2002 | 12153378 |
| transforming growth factor-beta response to mycobacterial infection in striped bass morone saxatilis and hybrid tilapia oreochromis spp. | striped bass (morone saxatilis) and hybrid tilapia (oreochromis spp.) were experimentally infected with mycobacterium marinum. splenic mononuclear cell transforming growth factor-beta (tgf-beta) mrna was measured by reverse transcription quantitative-competitive pcr (rt-qcpcr). in histologic sections of liver and anterior kidney, the area of each section that was occupied by granulomas and the total area of each section were measured by computer-assisted image analysis and compared as a proporti ... | 2003 | 12963276 |
| a recombinant vaccine expressing a mammalian mycobacterium sp. antigen is immunostimulatory but not protective in striped bass. | a recombinant vaccine was constructed for piscine mycobacteriosis utilizing a brucella abortus strain rb51 vector expressing a mammalian mycobacterium sp. 85a antigen. juvenile striped bass were inoculated with the resulting construct at doses equivalent to 10(6), 10(7), 10(8), 10(9), and 10(10) colony-forming units/fish. blood and tissue samples from these fish demonstrated significant specific humoral and cell-mediated immune responses towards the 85a antigen in a dose-dependent manner. howeve ... | 2003 | 12969635 |
| mycobacterium balnei, a new acid-fast bacillus occurring in swimming pools and capable of producing skin lesions in humans. | | 1954 | 13188762 |
| the pathogenic behavior of mycobacterium ulcerans and mycobacterium balnei in the mouse and the developing chick embryo. | | 1956 | 13313952 |
| [different behavior during a leprous reaction induced by the bcg test and the intradermal reaction with a mycobacterium marinum suspension]. | | 1956 | 13341124 |
| homologous and heterologous immunity in infections of mice with mycobacterium ulcerans and mycobacterium balnei. | | 1957 | 13444620 |