Publications

TitleAbstractYear
Filter
PMID
Filter
status of drug resistance of mycobacterium tuberculosis strains isolated from hospitalized patients in lucknow. 1979112054
[l-phase growth of mycobacteria. 2. consideration on the survival of tubercle bacillus in caseous lesion (author's transl)]. 1979112315
[inhibitory effect of tuberculoglycoprotein on lysosomal enzyme activity (author's transl)]. 1979112316
[combined infection with yersinia pseudotuberculosis and mycobacterium tuberculosis as a rare cause of obstructive icterus]. 1979112451
thoracic tuberculosis: clinical aspects. 1979112685
thoracic tuberculosis: laboratory aspects. 1979112686
pathology of tuberculosis. 1979112687
the flotation method for detection of tubercle bacilli in sputum smears.both the flotation smear examination and culture techniques yielded results for detection of tubercle bacilli which were superior to either direct smear examination or to examination of smear from liquefied or liquefied-centrifuged sputum specimens.1979112743
tuberculin hypersensitivity following bcg vaccination in brisbane school children.seven hundred and fifty brisbane school children were tuberculin tested, in paired groups, with purified protein derivatives of mycobacterium tuberculosis, bovis, bcg and avium. reaction to avian ppd were stronger than to any of the others used. this finding may be of some importance in interpreting the variation in protection afforded by bcg vaccination.1979112744
hydroxylamine sensitivity and salt tolerance in screening and identifying mycobacteria.hydroxylamine sensitivity offered no advantage over p-nitrobenzoic acid in distinguishing between tubercle bacilli and other (opportunist and non-significant) mycobacteria. it was of limited use in identification procedures. salt tolerance assisted in the identification of strains which may be mycobacterium triviale and m. chelonei var borstelense.1979112745
isoniazid inhibition of the synthesis of monounsaturated long-chain fatty acids in mycobacterium tuberculosis h37ra.isoniazid inhibited c(24) and c(26) monounsaturated fatty acid synthesis in mycobacterium tuberculosis h37ra. time courses of this inhibition and that of mycolic acid synthesis were similar.1979112917
delayed hypersensitivity in ambystoma mexicanum. 1979113261
effects of panax ginseng extracts on the growth of mycobacterium tuberculosis h37rv. 1979113372
influence of dimethyl sulfoxide (dmso) on restoring sensitivity of mycobacterial strains resistant to chemotherapeutic compounds. 1979113379
purification of antibodies to bacterial antigens by an immunoadsorbent and a method to quantify their reaction with insoluble bacterial targets.a combination of procedures was employed to develop a radioimmunoassay which quantified the binding of antibodies to antigens of either intact propionibacterium acnes or to antigens of insoluble extracts derived from the bacteria. reactive antibody populations were purified by use of bacterial immunoadsorbents which were prepared by coupling p. acnes to diethylaminoethyl cellulose. binding of antibodies was detected with [125i]staphylococcal protein a ([125i]spa) and optimal conditions for the a ...1979113462
[a long-term observation on previously treated cases of pulmonary tuberculosis retreated with rifampicin for more than six months (author's transl)]. 1979113607
lysosomal enzymes and microbicidal capacity of activated macrophage.a relation was sought between acid phosphatase contents and the presence of tubercle bacilli inside the peritoneal exudate cells (pec) of normal guinea pigs and those immunized with bcg. this was done to investigate the role lysosomal enzymes play in the microbicidal capacity of the cell. in both normal and immune animals tubercle bacilli were present only in those pec that contained acid phosphatase. cells without acid phosphatase did not contain bacilli. thus, only activated cells ingested bac ...1978113649
mechanisms of immunity in tuberculosis. 1979113763
[bactericidal effect of disinfectants on various strains of mycobacterium tuberculosis]. 1979113848
[the bacteriological principles of tuberculosis treatments]. 1979113863
[antitubercular drug therapy. in practice... one should remember]. 1979113864
self-inoculation with mycobacterium tuberculosis weiszfeiler w-115.after intracutaneous self-inoculation with 0.05 mg (wet weight) of mycobacterium tuberculosis w-115 containing approximately 600 000 viable units, the local reaction was observed during a period of 9 weeks. no adverse effects or general reaction were observed. from the lesion the w-115 strain was recultivated. it was labelled w-115(78)st vaccine strain and is used for further studies. on the basis of experiments on laboratory animals, monkeys, human new-borns and adults, the strain w-115 is cons ...1979113990
malonyl-coa decarboxylase from mycobacterium tuberculosis and pseudomonas fluorescens. 1979114118
mode of action of a mycobacterial water-soluble adjuvant, maf3. 1979114248
[transmissible modification induced in mycobacterium tuberculosis and mycobacterium bovis in vitro].a biologically active material (fraction "s") is isolated from cultures of scotochromogenic mycobacteria. mycobacterium tuberculosis, or mycobacterium bovis by disrupting the cells, sedimentation through 2.2 m sucrose, and ultrafiltration. the fraction "s" induces the modification of tubercle bacilli into non acid-fast bacteria forming smooth colonies on nutritive glycerol agar within 24-36 h of incubation. three new phenotypes are thus obtained; two proved to be stable upon subculturing. freque ...1979114293
the prevalence of anonymous mycobaeteria in both resistant as well as fresh cases of pulmonary tuberculosis in the local population of south east rajasthan. 1979114478
[current status and problems of tuberculosis. 10 years of experience in a general medicine department].one hundred and seventeen cases of tuberculous disease who came to the authors' observation in 10 years are described. some cases are illustrated in details just to point out the complexity and the different guises of clinical presentation and to underscore the importance of an high index of suspicion for tuberculosis in patients who are admitted to a ward of internal medicine. in 71 patients with active, progressive tuberculous disease, the diagnosis was confirmed by bacteriological findings in ...1979114891
deoxyribonucleic acid relatedness among species of slowly-growing mycobacteria.dna-dna hybridization is a reliable method for determining the phylogenetic relationship between bacterial strains the hybridization kinetics for dna from different slowly-growing mycobacteria were measured optically in a spectrophotometer. the results indicate that m. tuberculosis and m. bovis belong to one species. m. avium and m. intracellulare are two species, but some serotypes, now designated m. intracellulare, actually belong to m. avium.1979115225
[short term chemotherapy of tuberculosis. bactericidal mechanisms in short term chemotherapy]. 1978115526
[short term chemotherapy of tuberculosis. current experimental findings in short term chemotherapy]. 1978115527
canadian survey to determine the rate of drug resistance to isoniazid, pas and streptomycin in newly detected untreated tuberculosis patients and retreatment cases.in 1975, a survey was carried out in canada to determine the primary and acquired drug resistance of m. tuberculosis isolates to isoniazid (inh), para-aminosalicylic acid (pas) and streptomycin. the results of this investigation were compared with those of the primary drug resistant study of armstrong, undertaken in 1963-64. it revealed that primary drug resistance has increased from 4.9% to 6.3%. the increase is mainly due to immigrants having arrived in this country during the last 12 years. i ...1979115802
[scanning electron microscopy of drug resistant mycobacterium tuberculosis (author's transl)]. 1979116051
in vitro susceptibility of mycobacteria, especially of mycobacterium intracellulare, to 5-fluorouracil and pattern of development of resistance of mycobacterium tuberculosis to the drug. 1979116112
[importance of serological studies in the differential diagnosis of diseases of the osteoarticular system]. 1979116216
[ultrastructural change in mycobacterium tuberculosis under the influence of antibacterial preparations (a review of the literature)]. 1979116217
[bacillary elimination in patients with destructive pulmonary tuberculosis treated with intrabronchial infusion of tuberculostatics]. 1979116218
[frequency of mycobacterium tuberculosis elimination by persons with nonspecific lung diseases]. 1979116219
[distribution and multiplication of mycobacteria in water]. 1979116220
[relapse of pulmonary tuberculosis and factors contributing to their occurrence]. 1979116221
[characteristics of the mycobacteria isolated from urogenital tuberculosis patients]. 1979116222
[current bacteriologic and clinical aspects of chemo-antibiotic therapy of pulmonary tuberculosis]. 1978116622
diagnosis of tuberculosis. 1979116806
[the significance of the sporadic few colony isolates of mycobacterium tuberculosis--on the false-positive culture (author's transl)]. 1979117198
[secondary resistance in 544 cases of pulmonary tuberculosis in the adult]. 1979117276
[intralobal pulmonary sequestration and tuberculosis superinfection].among 16 pulmonary sequestrations observed in 23 years, 3 were associated with pulmonary tuberculosis. a detailed report is given on a 37-year-old man who was found by serendipity to have a right lower sequestration after 6 years treatment for tuberculosis; middle and upper lobe function had already been lost. two and half years after pneumonectomy, the patient is in good health. discussion centers on the diagnosis and potential complications of pulmonary sequestrations.1979117543
accidental contamination of diagnostic cultures of mycobacteria and phage identification of the contaminating strain.phage typing of mycobacteria is a new technique not yet widely used for classification and intraspecies differentiation. systematic long-term studies organized by the who have succeeded, using a battery of 11 different mycobacterial phages, in dividing m. tuberculosis into 3 different phage sub-groups, preliminarily labelled as a, b and c. a special case of phage-typing is presented which enabled identification of a virulent mycobacterial strain causing accidental contamination of diagnostic myc ...1979117577
[synthesis and tuberculostatic activity of various derivatives of 3-alkylthio- and 3-phenylthiopyrazine-2-carboxylic acids and thieno[2,3-b]pyrazine]. 1979117675
[a study on prevalence of resistance to primary and secondary drugs among newly admitted pulmonary tuberculosis patients in 1977. part 1. comparison of results in 1977 with those in 1957, '59, '61, '63, '66, '69 and '72 (author's transl)]. 1979118298
[a study on prevalence of resistance to primary and secondary drugs among newly admitted pulmonary tuberculosis patients in 1977. part 2. studies on the factors related to the prevalence of drug resistance (author's transl)]. 1979118299
[acute meningo-encephalitis in adolescents and adults--i. germs, rate of morbidity and lethality (author's transl)].diverse forms of acute meningo-encephalitis found in adolescents and adults are discussed considering 1244 cases treated at the neurologic clinic of the university at cologne in the time from 1950 till 1975. the rate of morbidity and lethality was found to vary according to the type of causative germ. the inflammation often took another course than in childhood. the age at the outbreak of the disease, infection immunity, precursing and concomitant illnesses as well as the onset of medication inf ...1979118326
[a few remarks on the immunity and hypersensitivity in tuberculosis]. 1979118494
the cytologic diagnosis of tuberculosis in pleural effusions.this paper reports on eight patients who had cytologic findings suggestive of florid pleural tuberculosis in pleural exudates. the suggestive diagnosis in each case was confirmed either by a pleural biopsy, culture of mycobacterium tuberculosis from the aspirated fluids or clinical improvement from the administration of tuberculotherapy. the pleural effusion from tuberculosis is characterized by the presence of abundant lymphocytes in the smear. the nuclei of the lymphocytes show characteristic ...1979118607
[tuberculin reactivity in tuberculosis patients carrying bacilli]. 1979118784
[a specific antigen present in strains of m. tuberculosis (proceedings)]. 1979118785
[a chemical structure in tuberculous bacilli responsible for epithelioid granuloma formation (proceedings)]. 1979118786
[experimental pulmonary cavity formation by mycobacterial components (proceedings)]. 1979118787
tuberculosis: the changing tubercle. 1979118789
tuberculosis: genitourinary tuberculosis.genitourinary tuberculosis should be managed on an outpatient basis, patients being seen once a week. the treatment of choice is a short-course regimen comprising 2 months of either three or fours drugs - streptomycin, rifampicin, isoniazid, and pyrazinamide - followed by isoniazid and rifampicin three times a week for either 2 or 4 months, depending on the severity of the lesion. patients should be followed-up, normally for one year, and be told to report to their doctors if they have any recur ...1979118790
identification of clinical isolates of mycobacteria with gas-liquid chromatography alone.identification of 18 mycobacterial species was performed by analysis of profiles obtained by using gas-liquid chromatography. organisms were saponified in methanolic naoh, and the reaction mixture was treated with bf(3) in methanol and extracted with a hexane-chloroform mixture. an identification scheme was developed from 128 stock strains and tested against a collection of 79 clinical isolates. by using gas-liquid chromatographic profiles alone, 58% of specimens were correctly identified to spe ...1979118984
isolation of acid-fast organisms from surgical specimens.a total of 204 surgical specimens positive for acid-fast organisms yielded 169 strains of mycobacterium tuberculosis, 15 of which were isolated by middlebrook 7h-9 broth medium only. mycobacteria other than m. tuberculosis were isolated from 33 specimens, and nocardia asteroides was isolated from 2 specimens.1979118985
altered lymphocyte response in adjuvant-induced arthritis.evaluation of lymphocyte response has been undertaken in adjuvant-induced arthritis in rats. lymphocyte reactivity was studied by evaluating lymphocyte transformation in mixed lymphocyte-chondrocyte cultures as well as the response to pha and m. tuberculosis. it was found that animals immunized with freund's complete adjuvant showed increased transformation when challenged with m. tuberculosis powder. however, there was a depressed response to pha and a markedly depressed response in mixed lymph ...1979119049
[numerical analysis of relationships among mycobacterium tuberculosis, m. africanum, m. bovis, and m. microti (author's transl)]. 1979119084
[tuberculous infection as viewed from the turnover of host cell lipids (author's transl)]. 1979119085
[pathology of epithelioid cell granulomas in relation to the cell components of mycobacterium tuberculosis]. 1979119086
regulatory mechanism of reagin production in mice at the t cell level. i. suggestive evidence for the generation of class specific ppd-reactive helper t cell population in mycobacterium-primed cells. 1979119137
[combined action of preparation k and antitubercular preparations on mycobacterium tuberculosis in vitro]. 1979119141
[drug resistance of tuberculosis mycobacteria in patients with relapses of coniotuberculosis]. 1979119142
[microbiological methods of mycobacterium tuberculosis isolation during intravenous administration of antibacterial aerosols]. 1979119222
[isolation of mycobacterium tuberculosis and its l-forms from caverns and sputum of patients with pulmonary tuberculosis]. 1979119223
immunoprofile studies in patients with pulmonary tuberculosis. ii. correlation of levels of different classes of immunoglobulins and specific antibodies with the extent of tuberculosis.humoral immune response of patients with newly detected, bacteriologically confirmed pulmonary tuberculosis was determined prior to initiation of chemotherapy. correlation with the extent of the disease was studied. a significant rise in the iga and igg levels in the serum was observed, the increase in the iga levels correlated with the extent of the disease. in tuberculous patients elevated levels of anti-ot (ppd) antibodies were found by haemaggluination, but no marked correlation was observed ...1979119315
[promptness in the diagnosis of tuberculosis patients]. 1979119324
[studies on pyrazine derivatives. xiv. synthesis and the tuberculostatic effect of pyrazinoamidrazones]. 1979119427
tuberculosis of the thyroid: two case reports.tuberculosis of the thyroid gland occurs only rarely. since extrapulmonary tuberculosis is now seen relatively more frequently the existence of this condition should be recognized. the cases of two patients with tuberculosis involving the thyroid are presented. the first, an asian immigrant, presented with a painless goitre with no evidence of tuberculosis elsewhere. the second was an english woman who presented with hypothyroidism due to destruction of the thyroid by tuberculosis, and who subse ...1979119548
"tween egg medium" for isolating mycobacteria from sputum specimens.'tween egg medium,' in which tween 80 was used as a carbon source, showed a higher rate of positive cultures than ogawa egg medium in isolation of mycobacteria from sputum specimens.1979119898
[spontaneous pneumothorax associated to active pulmonary tuberculosis].this paper reviewed 8 cases of spontaneous pneumothorax, associated to pulmonary tuberculosis during a period of time of two years at the a.l.m. general hospital of toluca, mex. the diagnosis was confirmed by clinical picture, radiology and bacteriology studies. six males and two females proceding of the low class; farmers all of them. their age ranged between 18 and 35 years. two of the patients showed cavitary lesions, five had difusse fibrosis of the lung. we analized the clinical manifestati ...1978119959
[resistance of the strains of mycobacterium tuberculosis isolated in the laboratory of the institute for tuberculosis and pulmonary diseases of serbia (author's transl)]. 1979119979
comparison of plain egg medium with lowenstein-jensen medium in the isolation of m. tuberculosis from sputum. 1979120316
differential tuberculin testing in children. 1979120364
correlation of the lymphocyte transformation, leucocyte migration inhibition and the delayed cutaneous hypersensitivity tests in chickens sensitised to mycobacterium tuberculosis. 1979120573
pseudotumoral tuberculosis of the esophagus. 1979120618
drug resistance in newly discovered untreated tuberculosis patients in poland, 1974-1977.between march 1974 and november 1977 altogether 2568 strains from 509 newly discovered, previously untreated tuberculosis patients from many areas of poland were tested for susceptibility to 4 antituberculosis drugs: isoniazid (inh), streptomycin (sm), ethambutol (emb) and rifampicin (rmp). twenty seven patients (5.3 %) were infected with tubercle bacilli resistant to 1 (4.1 %) or 2 drugs (1.2 %). sixteen patients (3.1 %) were infected with strains resistant to inh alone; t (1.0 %) to sm alone a ...1979120628
role of bovine serum albumin in the nutrition of mycobacterium tuberculosis.bovine serum albumin promotes the growth of small inocula of mycobacterium tuberculosis in media containing unesterified fatty acids. albumin binds fatty acids present in concentrations toxic for the organisms. in the present study, additional roles of albumin were investigated. when present in a basal medium, fatty acid-free albumin could be utilized by m. tuberculosis as a sole source of carbon. since albumin could not substitute for the amino acids in basal medium as a nitrogen source, it was ...1979120697
[role and value of bacteriology for the affirmative diagnosis of the cases of tuberculosis to be given priority as to chemotherapy]. 1979120970
[streptomycin in experimental tuberculosis of guinea pigs]. 1979121147
[synthesis and tuberculostatic activity of various derivatives of 2-mercaptoimidazo [4,5-c] pyridine]. 1979121515
[elastolytic activity in rat peritoneal cells--effects of vaccination with killed mycobacterium tuberculosis and intra-peritoneal administration of elastin particles (author's transl)]. 1979121550
treatment of pulmonary tuberculosis. 1979121586
[primary resistance observed in 974 strains of mycobacterium tuberculosis isolated from adult pulmonary patients]. 1979121595
first tuberculosis prevalence survey in kwazulu.the results of a prevalence survey undertaken during 1974 are presented. a stratified 3-stage sampling technique was used to select 3 789 people from 10 randomly chosen sites in kwazulu. one heaf test and 2 mantoux tests were performed on each of 1 769 children under 18 years of age, of whom 28,7% were found to have bcg scars. of the radiographs taken of persons 15 years of age and older, 893 were found to be negative, 25 (2,7%) disclosed active tuberculosis (tb) and 3 (0,3%) miliary tb. of the ...1979121637
potency of ppd preparations derived from m. tuberculosis and m. bovis.no significant difference was found between the biological activity of ppd-preparations derived from m. tuberculosis and m. bovis, although the latter was more potent. in potency tests performed in guinea-pigs, the use of difference mycobacteria as sensitizing agents had no influence on the result of the assay. we could not demonstrate a significantly greater potency of homologous versus heterologous ppd. evaluation of the 95 p.c. fiducial limits established in the course of variance analysis su ...1979121875
a comparative study on the pretreatment methods for the cultivation of mycobacterium tuberculosis on lj medium. part i.the sputa of 303 cases who were admitted at ojha sanitaurium karachi were studied for comparing the efficacy and reliability of the three pretreatment methods including the standard method, and those recommended by nassau (1958) and becker (1916). out of the total 223 cases were found to be positive after cultivation on lj medium out of which 142 were found positive with zncf staining while in 81 cases no afb could be detected. the number of cases found to be positive with standard method, becke ...1979121981
[the influence of drug-resistance in antituberculosis chemotherapy (author's transl)]. 1979122146
[results of different methods used for drug susceptibility of mycobacteria (author's transl)].fourty strains of mycobacteria have been tested for drug susceptibility using canneti's method of proportions: every strain has been tested using direct method, which provides results in a relatively short time, and using indirect method on primary cultures. results of two methods have been compared and time required to perform direct and indirect test has been related to one of rapid, impregnated disks, method.1979122154
automatable radiometric detection of growth of mycobacterium tuberculosis in selective media.the formulation of media for selective, automatable, radiometric detection of growth of mycobacterium tuberculosis in vitro is described. palmitic-1 acid labeled with carbon-14 and formic-14c acid were compared as substrate sources of [14c]o2 in media deficient in carbohydrate and containing appropriate antimicrobial agents that are not active against tubercle bacilli. a preliminary clinical laboratory study of a medium containing 4 microci palmitic-1-14c acid per ml showed that this method migh ...1977122228
[role of mycobacterium tuberculosis in bovine tuberculosis].the authors report the results of a survey on the possible role of human mycobacterium in the ganglio-pulmonary tuberculosis of bovines. 232 bovines seized in the abattoirs of algiers over a period of 8 months were concerned by this work. the results obtained showed that microscopic examination was negative in 50% of cases. this result was expected as ganglionary lesions are paucibacillary. cultures were also negative in 50% of cases, 25% of them were contaminated. 50% rate of positive cultures ...1978122307
[critical analysis of practical sensitivity tests in the evaluation of the primary resistance rate of tuberculosis bacilli to antibiotics].tuberculosis bacilli strains isolated from patients with pulmonary tuberculosis were tested to antituberculosis drugs in our laboratory since 1967 with the same method and by the same staff. however, there was a great fluctuation in the primary resistance rates calculated from one year to another and from one area to another. the analysis of strain sample showed that the main reasons were : the unprecision of patients questionnary, the preselection of strains sent to the laboratory and the unres ...1978122308
the transport (under tropical circumstances) of specimen to the laboratory for the cultivation of pathogens. iii. the shipment of sputum samples for the cultivation of mycobacterium tuberculosis. 1978122544
immunogenicity of an aerogenic bcg vaccine in t-cell-depleted and normal mice.aerogenic infection of adult thymectomized, lethally irradiated, bone marrow-reconstituted (thxb) c57b1 times c3h f1 hybrid mice with 1 to 3,000 viable bcg montreal was followed by an extended period of logarithmic growth to a maximum population of 5 times 10-6 bacilli by day 35. the infection spread to the liver, spleen, and bone marrow with extensive multiplication in all test organs before the growth curves abruptly entered a stationary phase. up to 30% of the thxb mice eventually died as a r ...1975123519
[drug resistance of mycobacterium tuberculosis in patients with pulmonary tuberculosis treated in the santorium in abastumani]. 1975124432
[bacteriological diagnosis of tuberculosis in childhood]. 1975125601
Displaying items 301 - 400 of 53400