| [on the method of determination of initial stages of glycerin metabolism in geographic varieties of the causative agent of tularemia]. | | 1968 | 4185826 |
| [differentiation of geographic races of francisella tularensis on the basis of citrulline ureidase activity]. | | 1970 | 4192178 |
| tularaemic pneumonia: pathogenesis of the aerosol-induced disease in monkeys. | | 1973 | 4200656 |
| zoonotic potential (rocky mountain spotted fever aed tularemia) in the tennessee valley region. ii. prevalence of rickettsia rickettsi and francisella tularensis in mammals and ticks from land between the lakes. | | 1974 | 4204021 |
| zoonotic potential (rocky mountain spotted fever and tularemia) in the tennessee valley region. i. ecologic studies of ticks infesting mammals in land between the lakes. | | 1974 | 4204030 |
| [isolation of the a-antigen of the tularemia microbe]. | | 1973 | 4205255 |
| [the physico-chemical properties and allergenic activity of peptides of various species of bacteria]. | | 1973 | 4205258 |
| [submicroscopic structure of the bacterial cell wall (review of the literature)]. | | 1973 | 4206610 |
| the mediator of cellular immunity. vii. localization of sensitized lymphocytes in inflammatory exudates. | peritoneal exudates induced in rats infected with listeria monocytogenes contain sensitized lymphocytes which can protect normal recipients against a listeria challenge. the protective cells arise in lymphoid tissue remote from the peritoneal cavity. those formed in the caudal lymph nodes of subcutaneously infected rats are delivered to the thoracic duct and hence to the blood from where they are drawn into exudates. immunoblasts are the most immature members of this protective cell population a ... | 1974 | 4208417 |
| [rapid processing of material for the antibody neutralization test in case of detection of antigen of tularemia and f-1 plague]. | | 1974 | 4214964 |
| vaccine potencies of the live vaccine strain of francisella tularensis and isolated bacterial components. | | 1974 | 4215444 |
| [p-antigen of the causative agent of tularemia]. | | 1974 | 4218034 |
| [plague, tularemia and anthrax immunization with associated di- and trivaccines using a jet injector. i]. | | 1974 | 4218042 |
| [studies on the sensitivity of francisella tularensis to antibiotics in vitro]. | | 1967 | 4229465 |
| [on the factors of the stable maintenance of natural microfoci of tularemia in the steppe zone of the stavropol area]. | | 1969 | 4239987 |
| [tularemia in the orenburg region. ii]. | | 1969 | 4239988 |
| [on the mechanism of persistence of the plague microbe on the plains of azerbaijan]. | | 1969 | 4240558 |
| tularemia in a pet squirrel monkey (saimiri sciureus). | | 1970 | 4249657 |
| production of interferon-like inhibitor in chickens after secondary induction by bacteria and virus. | | 1968 | 4385157 |
| characterization of the endogenous mediator(s) of serum zinc and iron depression during infection and other stresses. | | 1971 | 4399096 |
| the definition and application of evaluation techniques as a guide for the improvement of fluorescent antibody reagents. | | 1971 | 4400555 |
| further studies on tularemia in alaska: human tularemia. | | 1974 | 4434260 |
| further studies on tularemia in alaska: virulence and biochemical characteristics of indigenous strains. | | 1974 | 4434261 |
| [tularemia laboratory infection]. | | 1974 | 4445529 |
| [evaluation of tularemia vaccine strains in experiments on rabbits]. | | 1974 | 4454858 |
| [attempts at growing francisella tularensis in cell cultures in vitro]. | | 1974 | 4471744 |
| induced metabolic sequelae of tularemia in the rat: correlation with tissue damage. | serum and liver zinc concentration, amino acid uptake by liver, seromucoid content, and alpha2-macrofetoprotein production were measured in vaccinated as well as nonimmune rats exposed to either virulent (schu s4) or attenuated (lvs) strains of francisella tularensi. it appears that liver damage (pyogranulomatous lesions) must occur before there is any alteration in the above variables. the presence of bacteria in the liver is not of itself sufficient to lead to the onset of systemic, induced me ... | 1975 | 51592 |
| [biochemical, antigenic and protective properties of the outer membrane of tularemia pathogens]. | the outer membranes of francisella tularensis were studied. the membranes were identified morphologically, immunologically and biochemically. they contained 12-20% of protein, 15-30% of carbohydrates, up to 40% of lipids. the main integral proteins of the outer membranes were the 47, 43, 17 and 12 kd proteins. the main protein 63 kd was not integral. the lipopolysaccharides isolated from the outer membranes and acetone-dried cells did not possess the protective properties in experimental tularem ... | 1991 | 1745261 |
| [features of the interaction of escherichia coli and francisella tularensis rna polymerases with hybrid plasmids bearing fragments of francisella tularensis chromosomal dna]. | hybrid plasmids containing the fragments of francisella tularensis chromosomal dna and capable of tet-gene expression both in escherichia coli and francisella tularensis cells were constructed. the regions of francisella chromosomal dna binding the rna-polymerases of escherichia coli and francisella tularensis were found by the electron microscopy technique. interconnection of those regions with the expression of tet-gene of the hybrid plasmids was demonstrated. | 1991 | 1745260 |
| use of rna hybridization in the diagnosis of a case of ulceroglandular tularemia. | | 1990 | 1702055 |
| identification of francisella species and discrimination of type a and type b strains of f. tularensis by 16s rrna analysis. | tularemia is a zoonotic disease, occurring throughout the northern hemisphere. the causative agent, the bacterium francisella tularensis, is represented by two main types. type a is found in north america, whereas type b is mainly found in asia and europe and to a minor extent in north america. no routine technique for rapid diagnosis of tularemia has been generally applied. we have partially sequenced 16s rrnas of two f. tularensis strains, as well as the closely related francisella novicida. o ... | 1990 | 1692676 |
| [antigenic composition of outer membrane proteins of the tularemia pathogen]. | | 1990 | 2074891 |
| [special preventive immunization against early summer meningoencephalitis and tularemia for laborers of the natural gas central youth project in the ussr]. | | 1990 | 2165713 |
| [use of the elisa immunoenzyme method for the detection of the causative agent of tularemia]. | the conditions of the enzyme-linked immunosorbent assay (elisa) for the detection of francisella tularensis were worked out. in the study of 27 strains differing in their biological characteristics, the sensitivity of the assay was determined, varying within the range of 1 x 10(4)--5 x 10(4) million cells/ml and exceeding the sensitivity of the currently used methods for the immunodiagnosis of tularemia by 1-2 orders. elisa also proved to be a highly effective technique for the detection of the ... | 1988 | 2452535 |
| ulceroglandular tularemia: a typical case of relapse. | tularemia is an infectious disease that continues to occur sporadically and in epidemics in the united states. it is characterized as an acute febrile illness with constitutional symptoms associated with skin, glandular, respiratory, or gastrointestinal involvement. tularemia usually can be treated effectively with streptomycin. relapse most often occurs when patients are treated with bacteriostatic agents such as chloramphenicol or tetracycline. we present a case of ulceroglandular tularemia di ... | 1989 | 2606733 |
| [detection of tularemia pathogens in patients with the use of an immunofluorescence reaction]. | for the first time three cases of the detection of francisella tularensis, made by means of the direct immunofluorescence test in the fluid obtained from punctured buboes or in purulent matter taken from patients with the ulcerous bubonic form of tularemia, are presented. the simplicity of the test and its capacity of yielding rapid results make it possible to recommend this test, together with other diagnostic methods, for the clinical diagnosis of tularemia. | 1989 | 2660477 |
| [decrease in the cytogenetic effect of adriblastin and pharmorubicin with the experimental use of tularemia vaccine]. | immunization of wistar rats with tularemic vaccine has been studied for its influence on the cytogenetic effect of adryblastine and pharmorubicyn. it is shown that the number of aberrant metaphases considerably decreases in the myelocaryocytes of vaccinated rats. antimutagenic effect is induced by the influence of tularemic vaccine on the metabolic activation processes of antibiotics and, possibly, by an increase of the activity of antioxidative enzymes in the rat organism. | 1989 | 2815329 |
| [the effect of tularemia vaccine on the radioresistance of white rats exposed to x-irradiation]. | a single epicutaneous vaccination of wistar rats with tularemic live vaccine 15 days before x-irradiation with doses of 6.0, 8.0 and 2.0 + 6.0 gy was shown to increase their radioresistance. with higher doses (up to 8.0 gy) the effect of the vaccine was less pronounced. | 1989 | 2928478 |
| [the role of serological examination of the excrement of predatory birds for the evaluation of the epizootic situation]. | | 1987 | 3445555 |
| a waterborne tularemia outbreak. | a waterborne tularemia outbreak is described. forty nine cases were identified in sansepolcro, a small medioeval town in the province of arezzo, tuscany, italy. all cases had laterocervical or sub-mandibular adenitis, and occurred within a period of three weeks during march and april 1982. the study showed association between cases and the consumption of water from an unchlorinated water system. francisella tularensis type 1 was isolated from wild hares captured in the area. | 1987 | 3582597 |
| detection of antigen in urine of a patient with tularemia. | | 1987 | 3622500 |
| [epidemiology and prevention of tularemia]. | | 1987 | 3646961 |
| [effect of the immunization of rats with tularemia vaccine on the number of cytogenetic disorders in somatic cells induced by cytostatics]. | cytogenetic disturbances due to cytostatic preparations--cyclophosphamide and methylnitrosourea--applied as single or ten-times administrations in different doses have been studied for rats immunized with tularemia live dried vaccine. it is established that with the application of these preparations to immunized animals the quantity of chromosomal aberrations in myelokaryocytes decreased from 1.4 to 2.2 times, compared with that in non-immunized animals. | 1986 | 3715978 |
| [possible mutagenic action of a tularemia vaccine]. | no increase in the number of chromosome aberrations in the bone marrow cells of the wistar rats was observed on the 1st, 2nd, 7th and 15th days after epidermal and intradermal immunization by tularemic live vaccine. subcutaneous injection of great quantities of tularemic microbic cells which were not used in practice increased the number of cells with chromosome aberrations only on the second day. | 1986 | 3750405 |
| [enhanced antitumor resistance in rats immunized with a tularemia vaccine]. | it is established that rat immunization with tularemia living vaccine inhibits pliss lymphosarcoma growth and increases the life duration to tumour bearing animals. in tests with zajdela ascitic hepatoma in 1/3 of the immunized animals ascites were not formed and the rats lived 150 days before they were killed. | 1986 | 3753929 |
| [effect of a live tularemia vaccine on chemical mutagenesis in white rats]. | the influence of immunization with tularemic live dry vaccine applied singularly to wistar rats skin on mutagenicity induced by cyclophosphamide, methylnitrosourea, benzo (a) pyrene, chloroprene and tetrachlorbutane was studied. the chemical compounds indicated were injected intraperitoneally at doses equal to one fifth of ld50 in 15 days after vaccination. the same doses of these chemicals were applied to intact rats (controls). metaphase plates were prepared from rat bone marrows by known meth ... | 1985 | 3840760 |
| [effect of immunization with tularemia vaccine on 3,4-benz[a]pyrene-induced blastomogenesis and mutagenesis in rats]. | the living tularemia vaccine is studied for its effect on rat tumours and chromosome aberrations in bone marrow cells during 3,4-benz(a)pyrene injection (bp). it is established that a single epicutaneous vaccination of rats decreases the incidence of bp-induced tumours, prolongs the latent period and reduces the mean weight of tumours as well as lowers the number of myelocaryocytes with chromosome aberrations when bp is administered 15 days after immunization. 125 days after a single subcutaneou ... | 1985 | 3979338 |
| [experimental multifactorial study of the effect of doxycycline and glucosaminylmuramyl dipeptide on the primary immunologic response to antigens of a tularemia vaccine strain]. | the effect of the combined use of doxycycline and glucosaminylmuramyl dipeptide (gmdp) on the primary immune response to antigens of tularemia vaccine was studied on cba male mice with the use of the multifactorial design of experiment. antibodies to the blood serum of the immunized animals were determined by the passive hemagglutination test with the use of the tularemia antigen diagnosticum. the delayed type hypersensitivity was estimated by changes in the weight of the extremities of the expe ... | 1985 | 4026257 |
| [effect of immunization with live tularemia vaccine on the growth of various tumor strains in rats]. | the paper deals with a study of the effect of a single challenge with living tularemia vaccine on the growth of such transplantable tumors as zajdela's hepatoma, pliss' lymphosarcoma, walker's carcinosarcoma, schwetz' erythromyelosis and sarcoma 45 in wistar rats. immunization was followed by a significant (37.2-86%) inhibition of the rate of growth of the said tumors. ascites was detected in half the vaccinated animals of zajdela's hepatoma series, this being matched by 100% in controls. | 1985 | 4072086 |
| [effect of the combined use of rifampicin and a low-molecular immunomodulator of natural origin on the primary immune response to the antigens of a tularemia vaccinal strain]. | the effect of rifampicin combination with a natural low molecular immunomodulator on the primary immune response to the antigens of tularemia vaccine was studied with the methods of multifactor designing of the experiment. the dependence of the delayed hypersensitivity and antibody titer on doses of the antibiotic and immunomodulator and the time of the immunomodulator administration was manifested by the second order equation. nomographs for precise quantitative estimation of the doses and regi ... | 1985 | 4091512 |
| human infections with francisella tularensis in norway. development of a serological screening test. | | 1972 | 4503972 |
| first detection of tularaemia in domestic and wild mammals in iran. | during a study on the ecology of small-mammal-borne infections in iran, over 4 600 wild mammals were collected at 47 localities. attempts were made to isolate francisella tularensis from the spleens of 3 548 of these animals. all were found to be negative. in addition, sera from 200 sheep and cattle and from 39 wild mammals were tested: 8 sheep, 3 oxen, and 1 hedgehog showed evidence of recent infection. this is the first report of tularaemia in iran. the relationship of these findings to the po ... | 1973 | 4548386 |
| aerosol survival of pasteurella tularensis and the influence of relative humidity. | the aerosol survival in air was determined for pasteurella tularensis live vaccine strain (lvs) as a function of relative humidity (rh). three different preparations of bacteria were used: (i) liquid suspension of p. tularensis lvs in spent culture medium; (ii) powders of p. tularensis lvs freeze-dried in spent culture fluid; (iii) p. tularensis lvs freeze-dried in spent culture fluid and then reconstituted with distilled water and disseminated as a liquid suspension. preparation (i) gave greate ... | 1972 | 4551041 |
| infection-immunity in tularemia: specificity of cellular immunity. | the relationship between hypersensitivity and cellular resistance to infection with facultative intracellular parasites was studied in mice by using infection-immunity in tularemia as a model system. delayed hypersensitivity to antigenic fractions of francisella tularensis was first detected 6 to 7 days after immunization with viable f. tularensis vaccine, at which time immunity against challenge infection developed. both immunity and delayed-type sensitivity reached maximal levels by 9 to 10 da ... | 1972 | 4564560 |
| tularemia: dr. edward francis and his first 23 isolates of francisella tularensis. | | 1972 | 4570449 |
| [history of the study of the causative agent of tularemia]. | | 1973 | 4585673 |
| oysters: retention and excretion of three types of human waterborne disease bacteria. | | 1974 | 4586734 |
| [use of the fluorescent antibody technic for detection of the agent of tularemia in the organs of experimentally infected animals]. | | 1973 | 4595602 |
| [experimental mixed infection in muskrats (omsk hemorrhagic fever and tularemia)]. | | 1974 | 4613000 |
| [experimental production of specific fluorescent tularemia serum using a non-virulent strain]. | | 1974 | 4614554 |
| the antigenic structure of francisella tularensis. i. isolation of the ether antigen and its fractionation. | | 1972 | 4624012 |
| function of the alveolar macrophage in immunity. | | 1972 | 4624744 |
| the antigenic structure of francisella tularensis. ii. fractionation of the ether antigen on cellulose carriers and by gel filtration. | | 1972 | 4627016 |
| methods for the assessment of microbial populations recovered from enclosed aerosols. | | 1972 | 4627206 |
| rapid assays for the detection and determination of sparse populations of bacteria and bacteriophage t7 with radioactively labelled homologous antibodies. | | 1972 | 4627207 |
| pathogenesis of tularemia in monkeys aerogenically exposed to francisella tularensis 425. | the pathogenesis of tularemia was studied in groups of rhesus monkeys (macaca mulatta) that inhaled graded 10-fold doses ranging from 10 through 10(6) organisms of francisella tularensis 425, a strain highly virulent for the white mouse but of reduced virulence for the domestic rabbit. mean incubation periods ranged from 3 to 6 days followed by acute illness lasting 5 to 11 days with subsequent recovery of most animals. the higher inhaled doses resulted in shorter incubation periods, longer and ... | 1972 | 4629251 |
| susceptibility of tularemia bacilli to the antagonistic action of cocci. | | 1972 | 4632426 |
| experimental tularemia in macaca mulatta: relationship of aerosol particle size to the infectivity of airborne pasteurella tularensis. | ninety-six macaca mulatta were exposed to aerosol particles containing pasteurella tularensis. four different aerosols were employed that contained particle size distributions with median diameters of 2.1, 7.5, 12.5, or 24.0 mum. size distributions were calculated only for those particles observed by phase microscope to contain organisms. animals exposed to particles whose median diameters were either 2.1 or 7.5 mum were all infected and showed extensive infection of the lower respiratory tract, ... | 1972 | 4632469 |
| survival of airborne pasteurella tularensis at different atmospheric temperatures. | the aerosol survival, recovery, and death rate of pasteurella tularensis schu s5 disseminated in particle sizes of 1 to 5 mum were significantly affected by air temperature. the highest aerosol recovery of viable p. tularensis was observed within -7 and 3 c; the recovery decreased significantly below and above this temperature range. the death rate of airborne p. tularensis was not significantly influenced by an increase in temperature from -40 to 24 c. however, a progressive increase in atmosph ... | 1973 | 4633423 |
| [experience of a 25-year study of the stability of properties of tularemia vaccine strains]. | | 1972 | 4643653 |
| bacteriological study of a natural focus of tularemia in the lake reserve of srebrna, the silistra region, bulgaria. | | 1972 | 4673074 |
| [study of the toxicity of f. tularensis following the action of ionizing irradiation]. | | 1973 | 4711422 |
| tularemia epidemic associated with the deerfly. | | 1973 | 4740907 |
| tularemia. | | 1973 | 4740911 |
| effects of hypobaric hyperoxia on the development and activity of immune spleen cells. | | 1973 | 4744245 |
| [determination of fibrinolytic activity of the causative agent of tularemia]. | | 1973 | 4785009 |
| [change in the properties of the causative agent of tularemia due to erythromycin]. | | 1973 | 4785841 |
| afghan hedgehog, a new reservoir of tularemia. | | 1973 | 4801900 |
| nonspecific staining: its control in immunofluorescence examination of soil. | gelatin preparations were used to treat soil slides prior to addition of fluorescent antibody. nonspecific staining was avoided, with no detectable interference to specific staining. gelatin-rhodamine conjugates served to counterstain as well as to prevent nonspecific staining. | 1968 | 4880718 |
| influence of bacterial infection on serum enzymes of white rats. | infection of white rats with francisella tularensis (pasteurella tularensis) and salmonella typhimurium and exposure to the endotoxin of s. typhimurium stimulated significant increases in various serum enzymes including aldolase, lactate dehydrogenase, phosphohexose isomerase, isocitrate dehydrogenase, and glutamate-oxalacetate transaminase. the rates of changes in enzymatic activity after infection were directly related to the size of infecting dose and to the type of infective agent employed. ... | 1969 | 4886856 |
| tularemia epidemia: vermont, 1968. forty-seven cases linked to contact with muskrats. | | 1969 | 4891088 |
| the effects of francisella tularensis infection on iron metabolism in man. | | 1969 | 4894492 |
| cellular response of mice to infection with pasteurella tularensis (live vaccine strain) following continuous exposure to low dose gamma radiation. | | 1969 | 4898414 |
| preparation of agglutinating antisera and fluorescent-antibody conjugates against pasteurella tularensis in equines. | the serological response in burros and horses to the viable lvs strain of pasteurella tularensis was studied. high-titered agglutinating antisera and fluorescent-antibody conjugates were obtained in both groups of animals. maximum titers were obtained in horses 14 to 21 days after the start of vaccination and in burros 21 to 28 days after the start of vaccination. the use of woodhour's adjuvants or booster inoculations did not result in increased titers. | 1970 | 4917187 |
| demonstration of francisella tularensis (syn. pasteurella tularensis) in sylvan animals with the aid of fluorescent antibodies. | | 1970 | 4922256 |
| antitissue versus antimicrobial cellular immunity: a perspective. | | 1971 | 4941265 |
| effect of infection and endotoxicosis on plasma lactate dehydrogenase isozymes in white rats. | vertical slab electrophoresis in polyacrylamide gels was used to monitor changes in lactate dehydrogenase (ldh) isozymes in plasma of white rats during bacterial infection and endotoxin poisoning. peritoneal infection with francisella tularensis and salmonella typhimurium and administration of s. typhimurium endotoxin stimulated significant increases in plasma ldh-5. rates of change in enzyme activity after infection were directly related to size of infecting dose and type of agent employed. inf ... | 1971 | 4949502 |
| effect of aerosol age on the infectivity of airborne pasteurella tularensis for macaca mulatta and man. | sawyer, william d. (u.s. army medical unit, fort detrick, frederick, md.), joseph v. jemski, arthur l. hogge, jr., henry t. eigelsbach, elwood k. wolfe, harry g. dangerfield, william s. gochenour, jr., and dan crozier. effect of aerosol age on the infectivity of airborne pasteurella tularensis for macaca mulatta and man. j. bacteriol. 91:2180-2184. 1966.-in aging aerosols of pasteurella tularensis schu-s4, the respiratory infectivity for man and macaca mulatta decreased more rapidly than the via ... | 1966 | 4957611 |
| [a study of the antigenic composition of some strains of p. tularensis. i]. | | 1965 | 4960676 |
| a virus inhibitor circulating in the blood of chickens, induced by francisella tularensis and listeria monocytogenes. | | 1967 | 4961829 |
| polynucleotide homologies of brucella deoxyribonucleic acids. | deoxyribonucleic acids (dna's) extracted from organisms presently placed in the genus brucella (b. abortus, b. melitensis, b. neotomae, and b. suis) possessed very similar polynucleotide sequences. unlabeled, single-stranded dna fragments from b. abortus, b. melitensis, b. neotomae, and b. suis were equally effective in competing with the interaction of corresponding radiolabeled, single-stranded dna fragments with their homologous dna-agars. unlabeled fragments of b. ovis, however, did not comp ... | 1968 | 4966546 |
| [karyometric study of the reaction of cells in monolayer tissue culture of human embryo to infection with virulent bacterial strains]. | | 1966 | 4968845 |
| [immunochemical characteristics of 2 geographic strains of tularemia microbes]. | | 1967 | 4969633 |
| toxicity of open air to a variety of microorganisms. | | 1969 | 4975276 |
| effect of vaccine, route, and schedule on antibody response of rabbits to pasteurella tularensis. | the response of the rabbit to viable or killed whole-cell pasteurella tularensis vaccines was studied. the most practical preparation for the production of anti-p. tularensis antibodies was viable organisms of the live vaccine strain (lvs). the intravenous route of administration proved superior to either the subcutaneous or intradermal routes, and incorporation of lvs into freund's adjuvants did not result in increased levels of antibody. short-term hyperimmunization, three injections at weekly ... | 1969 | 4976322 |
| [on a method of setting up the indirect hemagglutination test with antibody-sensitized erythrocytes]. | | 1966 | 4978070 |
| [a study of the antigenic composition of various strains of the tularemia microbe. ii. comparative antigenic composition of a virulent and avirulent microbe]. | | 1966 | 4978575 |
| [antigenic and immunologic interrelationships between brucellae and the agents of tularemia]. | | 1967 | 4979510 |
| antibodies in nonhuman primate to selected bacterial antigens. | | 1969 | 4981658 |
| oral vaccination against tularemia in the monkeys. | | 1969 | 4982863 |