| a study of the capacity of myelinated and unmyelinated nerves to induce experimental allergic neuritis. | | 1972 | 5054702 |
| biological aspects of urban rat control. | | 1972 | 5063011 |
| [qualitative differentiation in the sympathicus by stimulation of thermosensitive regions]. | | 1972 | 5065971 |
| [antigenic structure of shigella. v. binding of neutral sugars in o-antigenic side chains of lipopolysaccharides from shigella flexneri 1b and variant y]. | | 1972 | 5083794 |
| septic gonococcal dermatitis. | the overall incidence in gonorrhoea of septic gonococcal dermatitis was found to be 1.9% (3% for the females and 0.7% for the males). in 23 patients the common presenting symptoms were arthritis or arthralgia and bouts of fever, but the characteristic skin lesions served as an early clue to the diagnosis, and neisseria gonorrhoeae was isolated from the genitourinary tract or from the blood. with the use of immunofluorescent techniques gonococci were also found in smears prepared from the skin le ... | 1971 | 5101355 |
| [appearance of sensitivities to the t phages and to colicins in shigella flexneri f6s surviving infection by a lisbonne phage. ii. role of the infecting phage in the appearance of sensitivities]. | | 1971 | 5143084 |
| the chemical nature of shigella flexneri group antigen factor 6. | | 1971 | 5166871 |
| resportion of shigella endotoxin. i. preparation of 32p labelled endotoxin of shigella flexneri. | | 1968 | 5254007 |
| purulent meningitis caused by shigella flexneri. a case report. | | 1971 | 5285267 |
| purulent meningitis caused by shigella flexneri. a case report. | | 1971 | 5286587 |
| studies on vaccination against bacillary dysentery. 1. immunization of mice against experimental shigella infection. | in the course of a series of experiments begun in 1954 a number of different killed vaccines prepared from shigella flexneri 1 and 2a serotypes were tested for their immunogenicity after intraperitoneal administration in mice followed by challenge with virulent organisms of the same serotype; some live vaccines were also tested intraperitoneally or orally.maintenance of the mice on freter's regimen proved a reliable method of rendering them susceptible to intestinal infection with streptomycin-r ... | 1965 | 5294178 |
| studies on vaccination against bacillary dysentery. 2. safety tests and reactogenicity studies on a live dysentery vaccine intended for use in field trials. | in view of the encouraging results obtained in active mouse protection experiments, several batches of live oral vaccine prepared from streptomycin-dependent shigella flexneri were tested in vitro for any indication of reversion to streptomycin-independence and in man for their reactogenicity.the in vitro tests provided no evidence of reversion.in man, major reactions were observed in only 1.4% of volunteers, all those so affected being heterotypic shigella carriers in whom clinical exacerbation ... | 1965 | 5294179 |
| studies on vaccination against bacillary dysentery. 3. effective oral immunization against shigella flexneri 2a in a field trial. | in may 1963 a live vaccine prepared from streptomycin-dependent shigella flexneri 2a was administered to 355 soldiers stationed in an area of yugoslavia in which bacillary dysentery was hyperendemic. five oral doses were given every third day. 382 unvaccinated soldiers from the same unit served as controls. both groups were closely followed up until 16 september.examination of 1637 rectal swabs from the vaccinated and control groups indicated that vaccination did not affect the carrier rate. the ... | 1965 | 5294180 |
| male specific bacteriophage in shigella flexneri. ii. growth characteristics of phage in f'+ shigella. | | 1966 | 5297025 |
| plasmid-episome interactions in shigella flexneri. | | 1968 | 5301323 |
| the immunochemistry of shigella flexneri o-antigens: a serological classification of rough mutants. | | 1968 | 5301543 |
| studies on vaccination against bacillary dysentery. 4. oral immunization with live monotypic and combined vaccines. | results of tests made in 1964 confirm the previous findings that live oral vaccine, prepared from streptomycin-dependent strains of shigellae, confers a strong, type-specific protection against acute bacillary dysentery. this vaccine did not reduce the carrier rate of shigellae. observations on soldiers treated with a vaccine of shigella flexneri serotypes 2a and 3 combined revealed no antagonizing effects from the type 3 component upon the protective effect of the 2a component contained in the ... | 1968 | 5303905 |
| radiation protection of shigella flexneri y6r by ethanol, beta-mercaptoethanol and several polyhydric alcohols. | | 1969 | 5305956 |
| effect of active or passive immunization on the response of the ligated rabbit intestine to shigella flexneri infection. | | 1969 | 5309565 |
| effects of epinephrine and endotoxin (shigella flexneri 2b) on arterial endothelial surfaces observed by scanning electron microscope. | | 1970 | 5313273 |
| [antidysentery vaccination. xi. a. pathogenic action on the guinea pig intestine following the administration "per os" of shigella flexneri 2a strains (pathogenic and non-pathogenic for guinea pig conjunctiva). b. attempted immunization by oral route as compared to the intraperitoneal route]. | | 1964 | 5318791 |
| hybrids of escherichia coli and shigella flexneri 1b. | | 1966 | 5331420 |
| development of h-sh and p1kcvir phages in shigella flexneri f6s studied by fluorescence microscopy and electron microscopy. | | 1966 | 5333382 |
| [studies on the duration of life of shigella flexneri and shigella sonnei in artificially infected milk and milk products]. | | 1965 | 5333548 |
| [the resistance of antigenic components of shigella flexneri. 3. the effect of merthiolate and other chemical substances on the antigenic properties of microbes]. | | 1969 | 5372771 |
| [antigenic conversions in shigella flexneri. 2. effects of lysogenization of serotype 1, serotype 2, variant x and variant y cultures by a phage isolated from a serotype 5 culture]. | | 1969 | 5373656 |
| new scheme of phage typing of shigella flexneri. | | 1969 | 5398949 |
| study of the structure of shigella flexneri o antigen. i. chemical degradation. | | 1970 | 5418717 |
| study of the structure of shigella flexneri o antigen. ii. physicochemical aspect. | | 1970 | 5418718 |
| chemotherapy of mice experimentally infected with shigella flexneri. | a chronic infection with shigella flexneri 2a has been established in mice for the evaluation of compounds for therapeutic potential. evidence of infection is indicated by prolonged symptomless excretion in the feces and by positive isolation of organisms from different segments of the intestinal tract and from mesenteric lymph nodes. serum antibody titer reaches a maximum after 9 days of infection and remains at a low level until 32 days postinfection. in this model, five drugs used in human sh ... | 1970 | 5422307 |
| isolation and selection of auxotrophic and fermentative mutants of shigella flexneri. | | 1970 | 5455473 |
| [immunochemistry of shigella. 3. specific polysaccharides of shigella flexneri types: 2,3 and 6]. | | 1970 | 5459382 |
| shigella flexneri dysentery in the australian forces in south vietnam. | | 1970 | 5467372 |
| chemoprophylaxis of shigella flexneri keratoconjunctivitis in rabbits. | chloramphenicol, chlortetracycline, streptomycin, and sulfisoxazole prevented keratoconjunctivitis in rabbit eyes infected with shigella flexneri. the route of administration of the agent and the dose were important variables in controlling the infectious process. this assay system appears to be a useful technique for the in vivo evaluation of chemotherapeutic agents. | 1970 | 5485732 |
| morphology of bacteriophages used for typing shigella flexneri. | | 1970 | 5493081 |
| the immunochemistry of shigella flexneri o-antigens: a new serologically active trisaccharide from variant y. | | 1970 | 5500288 |
| [shigella flexneri f6s with extended patterns of sensitivity to the t phages and to colicins after infection by a lisbonne phage. 1. modified biological properties of the bacterial surface]. | | 1971 | 5564194 |
| concerning the classification of shigella flexneri 6 bacilli. | | 1967 | 5588833 |
| s-r dissociation in shigella flexneri populations. 3. respiration of smooth and rough forms. | | 1967 | 5588835 |
| phage typing, colicin sensitivity and colicinogeny of shigella flexneri 6. | | 1967 | 5591942 |
| the immunochemistry of shigella flexneri o-antigens: an analysis of the immunodominant sugars in lipopolysaccharides from smooth strains. | | 1968 | 5650132 |
| the immunochemistry of shigella flexneri o-antigens a study of smooth to rough mutation. | | 1968 | 5664129 |
| lysotypes of shigella flexneri. | | 1968 | 5664130 |
| resistance of shigella flexneri to antibiotics. | | 1968 | 5666680 |
| phage typing of shigella flexneri. | | 1968 | 5666687 |
| transferable multiple drug resistance in enterobacteria from non-human primates. i. development and characteristics of resistance in shigella flexneri. | | 1968 | 5667656 |
| [stability of the antigenic components of shigella flexneri. i]. | | 1968 | 5729700 |
| the response of man to virulent shigella flexneri 2a. | | 1969 | 5780532 |
| [stability of the antigenic components of shigella flexneri. ii. supplement to the characteristics of type antigens i, 3 and v]. | | 1969 | 5784553 |
| response and specificity of antibodies for shigella flexneri: demonstration of type-specific factors in immunoglobulin g fraction of antiserum. | considerable amounts of immunoglobulin g (igg) antibody appeared in hyperimmune rabbit serum at a late period during a course of immunization with several injections of shigella flexneri o antigens. high yields of igg antibody possessing homogenous specificity could be fractionated from crude gamma-globulin solution on a diethylaminoethyl-sephadex column with 0.02 m phosphate buffer (ph 6.6) containing 0.1 m nacl. specificities of igg antibodies for six serotypes of s. flexneri were demonstrated ... | 1969 | 5788700 |
| circular dna from shigella paradysenteriae. | | 1969 | 5804495 |
| [extraordinary place of discovery (vagina) of shigella flexneri]. | | 1969 | 5804669 |
| the immunochemistry of shigella flexneri o-antigens: a comparative analysis of the o-specific side-chain structures of serotypes 1a and 2a. | | 1969 | 5810099 |
| [lysotyping of shigella. v. provisional scheme for lysotyping of shigella flexneri type 3a]. | | 1964 | 5830282 |
| the mechanism of antagonism between antigenic types of dysentery bacilli of the shigella flexneri subgroup. | | 1965 | 5837179 |
| [study on the streptomycin-dependent shigella flexneri strain for oral vaccination against dysentery]. | | 1965 | 5848528 |
| [shigella flexneri in cat experiments]. | | 1965 | 5860519 |
| survival of shigella in sewage. 3. effect of glycerol on intracellular growth of bacteriophage in shigella flexneri. | | 1965 | 5867663 |
| shigella flexneri serovariants containing combinations of type antigens. | | 1965 | 5870704 |
| [research on active immunity of man in bacillary dysentery. 3. maintenance of the non-pathogenic character of the shigella flexneri 2a txxxii strain orally administered to volunteers]. | | 1965 | 5877879 |
| the effect of dysentery bacteriophage on the course of experimental cystitis produced in guinea-pigs by shigella flexneri. | | 1965 | 5893861 |
| the immunochemistry of shigella flexneri lipopolysaccharides. a quantitative analysis of their monosaccharide constituents. | 1. the lipopolysaccharides of a representative selection of shigella flexneri serotypes all contain the same constituents as salmonella chemotype vii, namely, aldoheptose phosphate, 3-deoxy-2-oxo-octonate, o-phosphorylethanolamine, d-galactose, d-glucose, n-acetyl-d-glucosamine and l-rhamnose. 2. the presence of all the salmonella basal sugars in sh. flexneri lipopolysaccharides is consistent with the view that the latter contain a basal structure or core which is similar to the common basal str ... | 1966 | 5911535 |
| shigella flexneri bacteraemia: report of a case. | | 1966 | 5947868 |
| [proposition to change the serologic designation of types and subtypes of shigella flexneri]. | | 1966 | 5959783 |
| [shigella flexneri bacteremia]. | | 1966 | 5967209 |
| shigella flexneri f6s strains with acquired sensitivities to the t phages after infection by lisbonne phages. | | 1966 | 5970172 |
| [antidysenteric vaccination. xiv. immunizing action on the guinea pig conjunctiva of various toxic extracts of pathogenic shigella flexneri 2a ti, as compared with that of live cultures of two non-pathogenic strains of shigella flexneri 2a]. | | 1966 | 5973711 |
| [lysotyping of shigella flexneri strains 2a and 3a isolated from several epidemic foci in rumania]. | | 1966 | 5981233 |
| [antidysenteric vaccination. xv. immunogenicity of various strains of shigella schmitzi shigella flexneri 1b, 2b, 3a, 4, 6, shigella boydii and shigella sonnei "s" in relation to the immunogenicity of a keratoconjunctivitis positive enterobacterium lacking shigella antigens (agglutinogens) (strain "well 3")]. | | 1966 | 5985458 |
| [studies on the antigen structure of shigellae. 1. studies on the chemical composition of lipopolysaccharides of a shigella flexneri s and r form and comparison with a salmonella r form]. | | 1966 | 5994748 |
| inhibition of shigella flexneri by the normal intestinal flora. i. mechanisms of inhibition by klebsiella. | growth curves were plotted for shigella flexneri and klebsiella (aerobacter aerogenes) multiplying in pure and mixed culture. in mixed culture, klebsiella inhibited shigella. exponential growth was interrupted and shigella entered into a logarithmic death phase. an analysis of cultures at the time inhibition occurred revealed that formic and acetic acids produced by klebsiella were responsible for the inhibition of shigella. klebsiella strongly reduced the culture medium. the volatile fatty acid ... | 1967 | 6032512 |
| immunochemical studies on shigella flexneri polysaccharides. | | 1967 | 6050439 |
| studies on the virulence of shigella flexneri. | | 1967 | 6057577 |
| interference of lysogenic shigella flexneri with antimicrobial disc susceptibility readings. | | 1967 | 6058731 |
| the immunochemistry of shigella flexneri o-antigens. the biochemical basis of smooth to rough mutation. | 1. smooth to rough mutation has the same biochemical basis in shigella as in salmonella. it is the result of enzyme defects blocking the incorporation of the o-specific side chains that characterize the smooth lipopolysaccharide with the consequent exposure of the underlying basal structures that determine ;rough'-specificity. 2. the shigella flexneri basal structure resembles its salmonella analogue in that it has the same qualitative sugar composition, and enzyme defects in its biosynthetic pa ... | 1967 | 6060453 |
| [role of specific bacteriophage in the control of the carrier state of shigella flexneri 6 bacilli]. | | 1967 | 6066184 |
| [immunochemical analysis of oligosaccharide fragments of o-specific shigella flexneri polysaccharides]. | comparison of inhibitory properties of several synthetic oligosaccharides related to sh. flexneri o-specific polysaccharides, namely glc alpha 1-3rha alpha 1-ome, glc alpha 1-3rha alpha 1-2rha alpha 1-ome, rha alpha 1-2(glc alpha 1-3)rha alpha 1-ome, glcnac beta 1-2(glc alpha 1-3)rha alpha 1-ome, and glcnac beta 1-2(glc alpha 1-3) rha alpha 1-2rha alpha 1-ome, using passive haemagglutination reaction demonstrated the tetrasaccharide to possess the highest activity in v; 7,8-anti-7,8 immune syste ... | 1984 | 6083795 |
| glycocalyx visualization in shigella flexneri. | | 1984 | 6085609 |
| [in vitro activity of a new cephalosporin (ceftriaxone) on recently isolated strains of shigella]. | | 1984 | 6088342 |
| virulence of entamoeba histolytica trophozoites. effects of bacteria, microaerobic conditions, and metronidazole. | the association of axenically grown trophozoites of entamoeba histolytica strains hk-9 or hm-1:imss with various types of gram-negative bacteria for relatively short periods markedly increased their virulence, as evidenced by their ability to destroy monolayers of tissue-cultured cells. interaction of trophozoites with bacteria that were heat inactivated, glutaraldehyde fixed, or disrupted by sonication, or bacteria treated with inhibitors of protein synthesis, did not augment amebic virulence. ... | 1984 | 6088660 |
| cloning and characterization of reca genes from proteus vulgaris, erwinia carotovora, shigella flexneri, and escherichia coli b/r. | the reca genes of proteus vulgaris, erwinia carotovora, shigella flexneri and escherichia coli b/r have been isolated and introduced into escherichia coli k-12. all the heterologous genes restore resistance to killing by uv irradiation and the mutagen 4-nitroquinoline-1-oxide in reca- e. coli k-12 hosts. recombination proficiency is also restored as measured by formation of lac+ recombinants from duplicated mutant lacz genes and the ability to propagate phage lambda derivatives requiring host re ... | 1984 | 6090408 |
| aerobactin genes in shigella spp. | aerobactin, a hydroxamate iron transport compound, is synthesized by some, but not all, shigella species. conjugation and hybridization studies indicated that the genes for the synthesis and transport of aerobactin are linked and are found on the chromosome of shigella flexneri, s. boydii, and s. sonnei. the genes were not found in s. dysenteriae. a number of aerobactin synthesis mutants and transport mutants have been isolated. the most common mutations are deletions of the biosynthesis or bios ... | 1984 | 6090419 |
| mercuric ion-resistance operons of plasmid r100 and transposon tn501: the beginning of the operon including the regulatory region and the first two structural genes. | the mercuric ion-resistance operons of plasmid r100 (originally from shigella) and transposon tn501 (originally from a plasmid isolated in pseudomonas) have been compared by dna sequence analysis. the sequences for the first 1340 base pairs of tn501 are given with the best alignment with the comparable 1319 base pairs of r100. the homology between the two sequences starts at base 58 after the end of the insertion sequence is-1 of r100. the sequences include the transcriptional regulatory region, ... | 1984 | 6091128 |
| evidence for clustering of rna polymerase and ribosomal protein genes in six species of enterobacteria. | 32p-labelled dna fragments from the e. coli beta operon were used as hybridisation probes for homologous dna sequences in chromosomal digests of six species of enterobacteria. in all species the hybridisation pattern suggested clustering of the genes comprising the beta operon. | 1984 | 6092848 |
| periodontal disease associated with shigella flexneri in rhesus monkeys. clinical, microbiologic and histopathologic findings. | | 1982 | 6124590 |
| genetic transfer of a mucosal adherence factor (r1) from an enteropathogenic escherichia coli strain into a shigella flexneri strain and the phenotypic suppression of this adherence factor. | escherichia coli strain rdec-1 avidly adheres to rabbit ileal brush borders. two separate experiments were designed to determine whether pili promote this adherence. (1) adherence of strain rdec-1 was phenotypically suppressed by changing the culture medium. loss of adherence was correlated with the absence of pili. thus, growth of strain rdec-1 in penassay broth (difco laboratories, detroit, mich.) promoted both adherence and expression of pili on greater than or equal to 90% of organisms, wher ... | 1983 | 6132950 |
| antigenic relationship among virulent enteroinvasive escherichia coli, shigella flexneri, and shigella sonnei detected by elisa. | | 1983 | 6134933 |
| immunologic observations in macaques with shigella-associated periodontal disease. | | 1983 | 6135769 |
| changes in phage-sensitivity of shigella flexneri strains. ii. the f-like character of ms2-sensitive variants. | variants sensitive to male specific phage ms2 appeared among ms2 non-sensitive shigella flexneri cultures in the course of liquid medium passages. sensitivity to ms2 was lost on acridine orange treatment and was transferable into ms2 non-sensitive variants. the ms2 sensitive variants had fimbrial antigen. electron microscopy showed that ms2 phages were adsorbed on the f-like fimbriae of these variants. it was assumed that f-like plasmids determining f-like fimbrial antigen were carried by these ... | 1983 | 6140808 |
| peyer's patch lymphoid follicle epithelial adherence of a rabbit enteropathogenic escherichia coli (strain rdec-1). role of plasmid-mediated pili in initial adherence. | escherichia coli (strain rdec-1) adheres to m cells of rabbit peyer's patch lymphoid follicle epithelium. the rdec-1 strain contains an 85 x 10(6) d plasmid that codes for pili, which, when purified, adhere to gut absorptive epithelium. this study compared the in vivo lymphoid follicle adherence of the rdec-1 strain with that of a shigella flexneri (shd15) that contained the 85 x 10(6) d plasmid and expressed the rdec-1 pili, a control e. coli, and a control s. flexneri (shd12). the bacteria wer ... | 1984 | 6145724 |
| [the conjugation system determined by plasmid r477 and other plasmids belonging to the h2 incompatibility group]. | | 1984 | 6148780 |
| early colonic lesions in experimental shigella infection in rhesus monkeys: revisited. | rhesus monkeys (macaca mulatta), given 3 x 10(8) to 5 x 10(10) shigella flexneri 2a orally, developed signs of acute shigellosis within 24 hours. a diffuse acute colitis was well established at 48 hours. the inflammatory reaction was confined to the mucosa. the submucosa showed only edema. the shigellae were found predominantly in the columnar cells of the surface epithelium, less frequently in those of the crypt, and least frequently in the lamina propria. shigella bacilli invaded the columnar ... | 1982 | 6153000 |
| stimulation of prostaglandin e production by bacterial endotoxins in cultured human synovial fibroblasts. | e coli, shigella, salmonella, and cholera endotoxins stimulated prostaglandin e (pge) production by cultured human synovial and foreskin fibroblasts. the minimal effective dose of shigella endotoxin was 2 micrograms/ml and a maximal response was observed at 10 micrograms/ml. pge stimulation was first detected 7 hours after addition of cholera endotoxin. stimulation by shigella endotoxin of both pge and hyaluronic acid production was inhibited by indomethacin and aspirin. the present results sugg ... | 1980 | 6157394 |
| serological analysis of core oligosaccharides of shigella flexneri serotype 6 and its r mutants lipopolysaccharides. | the core oligosaccharides originating from shigella flexneri 6 s strains and r mutants were examined by the complement fixation inhibition and passive hemolysis inhibition tests using antisera against the complete and partially degraded core regions. strong cross reactivity between shigella flexneri 6, shigella sonnei phase ii and e. coli c core fractions which all are of r1 type was observed. terminal beta-d-glucosyl groups and alpha-d-galactosyl-1,2-alpha-d-galactosyl sequences are essential e ... | 1981 | 6181755 |
| [obtaining dysentery and salmonellosis diagnostica for the coagglutination reaction in lyophilized form and the elaboration of a rapid system]. | | 1982 | 6182376 |
| [immunoelectrophoresis analysis of the antigenic composition of e. coli k12 hybrids which acquired the serological specificity of s. newcastle and s. flexneri]. | genetic and immunoelectrophoretic studies confirm earlier data on the presence of 2 specific antigens of acidic nature in s. newcastle; one of them is a specific thermolabile k-antigen responsible for type iv specificity of these bacteria. the data concerning the differences in the genetic determinants controlling the synthesis of o- and k-antigens in s. newcastle have been obtained. s. newcastle o- and k-antigens did not react with s. flexneri in the group serum system 3, 4, which indicates tha ... | 1982 | 6184914 |
| hela cell invasiveness and o antigen of shigella flexneri as separate and prerequisite attributes of virulence to evoke keratoconjunctivitis in guinea pigs. | many rough mutants selected from isogenic smooth virulent and avirulent strains of shigella flexneri were examined for virulence, using tissue culture infection and sereny tests. many of the rough mutants isolated from a virulent smooth strain were capable of penetrating tissue culture cells but incapable of producing a positive sereny test. in contrast, we could not obtain from smooth avirulent strains any rough mutants capable of penetrating hela cells. chemical analysis of lipopolysaccharide ... | 1983 | 6187681 |
| [stimulation of replication and increase in virulence of shigella growing in rna-containing media]. | | 1983 | 6188298 |
| [causes of the nonspecific reactions with antigenic erythrocyte diagnostic reagents]. | the causes leading to the appearance of positive reactions in diagnostic titers (1:200 and higher), registered in the sera of healthy persons in tests carried out with the use of experimental and commercial lots of shigella sonnei and shigella flexneri antigenic diagnostic reagents, are analyzed. the study has shown that the appearance of nonspecific reactions may be due to the influence of the initial state of the microbial culture (the biomass used as raw material for the production of sensiti ... | 1983 | 6191477 |
| [a new antigenic variety of shigella flexneri]. | | 1983 | 6194615 |