| in vitro activity of pd 127,391, an enhanced-spectrum quinolone. | the in vitro activity of pd 127,391, a dihalogenated quinolone, was compared with those of ofloxacin, ciprofloxacin, nalidixic acid, gentamicin, and cefuroxime against 525 recent isolates and well-characterized antimicrobial agent-resistant strains. the mics of pd 127,391 against 90% of members of the family enterobacteriaceae, bacteroides fragilis, haemophilus influenzae, neisseria sp., and streptococcus pneumoniae were less than or equal to 0.12 microgram/ml. some 90% of pseudomonas aeruginosa ... | 1988 | 3142350 |
| differentiation of sarcoidosis from tuberculosis using an enzyme-linked immunosorbent assay for the detection of antibodies against mycobacterium tuberculosis. | this study evaluates the ability of an enzyme-linked immunosorbent assay (elisa) using adsorbed mycobacterial sonicates as antigen to differentiate between patients with tuberculosis (tb) and patients with sarcoidosis. the study group consisted of 11 patients with active sarcoidosis, seven patients with sputum-positive tuberculosis, and seven normal control subjects. serum specimens were subjected to elisa. serum anti-tb igg optical density measured at 492 nm (mean +/- sd); pulmonary tb, 0.291 + ... | 1988 | 3142723 |
| [determination of antibodies to mycobacterial antigens in tuberculosis by erythrocyte immunoadsorption with a rosette marker]. | a solid-phase enzyme immunoassay system for the determination of antibodies to mycobacterial antigens, based on the method of erythrocyte immunoadsorption in microchambers for immunological reactions, has been developed. to detect antibodies specifically bound with the solid-phase antigen, the affinity rosettes of staphylococcus aureus strain cowan i, carrying protein a, with erythrocytes conjugated with human gamma globulin have been used. the significant correlation of the titers of 34 sera, d ... | 1988 | 3143209 |
| effectiveness of ofloxacin against mycobacterium tuberculosis and mycobacterium avium, and rifampin against m. tuberculosis in cultured human macrophages. | ofloxacin (ofl) is a new broad-spectrum drug with potentially valuable antimycobacterial activity. it was tested for ability to inhibit virulent tubercle bacilli (tb) and virulent mycobacterium avium in cultured human macrophages (mp). the first-line antituberculosis drug rifampin (rmp) also was tested against tb in mp. the drugs were added to the mp cultures immediately after infection or 2 days later. antimicrobial inhibition was measured by colony-forming-unit (cfu) counts of bacilli from lys ... | 1988 | 3143278 |
| identification of an effective vaccine against tuberculosis. | | 1988 | 3143288 |
| in vitro susceptibilities of mycobacterium tuberculosis to 10 antimicrobial agents. | after preliminary in vitro screening of 10 antimicrobial agents against mycobacterium tuberculosis, the mics of the 6 most promising agents against 27 clinical isolates were determined by agar dilution. the two quinolone compounds tested (difloxacin and a-56620) were the most active, each inhibiting 50% of the strains at concentrations of 4 micrograms/ml. m. tuberculosis strains previously shown to be resistant to isoniazid, streptomycin, rifampin, or ethambutol were as susceptible to these quin ... | 1988 | 3143305 |
| [diagnostic value of fiberoptic bronchoscopy examination in smear-negative pulmonary tuberculosis]. | | 1988 | 3143486 |
| [specificity of monoclonal antibody tb-15 c3 to mycobacterium tuberculosis]. | | 1988 | 3143487 |
| relative cross reactivity of habanin, lepromin and tuberculin in guinea pigs sensitized with homologous and heterologous mycobacteria. | an atypical strain mycobacterium habana has been studied for its antigenic cross reactivity with delayed type of hypersensitivity responses in guinea pigs. guinea pigs sensitized with m. habana, m. leprae and m. tuberculosis when challenged with habanin, lepromin and tuberculin in criss-cross fashion have demonstrated strong cross reactivity with each other. possibilities of developing m. habana as a vaccine against tuberculosis and/or leprosy has been discussed. | 1988 | 3143770 |
| attachment of mycobacteria to fibronectin-coated surfaces. | this report investigates the extent of the expression of fibronectin (fn) binding properties among the mycobacteria and provides preliminary characteristics of the bacterial molecule(s) mediating attachment. eight bcg substrains, three mycobacterium tuberculosis strains and four other mycobacterial species all expressed fn-binding capacity. treatment of organisms with detergent prior to the binding assay destroyed the fn-binding capacity of bcg but not that of staphylococcus aureus. trypsin pret ... | 1988 | 3143807 |
| antigenic relatedness of a strongly immunogenic 65 kda mycobacterial protein antigen with a similarly sized ubiquitous bacterial common antigen. | in gene libraries of mycobacterium bovis bcg, mycobacterium tuberculosis and mycobacterium leprae recombinants were frequently found expressing an immunodominant 65 kda protein antigen. in this study polyclonal and monoclonal antibodies against the 65 kda antigen were found to react with a variety of different bacteria. furthermore it is shown that the 65 kda mycobacterial protein belongs to the family of antigens previously designated 'common antigen' due to their presence in a large variety of ... | 1988 | 3143894 |
| [methods in the modern chemotherapy of tuberculosis (a lecture)]. | | 1988 | 3143997 |
| [the pathogenicity factors of mycobacterium tuberculosis]. | | 1988 | 3143998 |
| lymphadenopathy in an inner-city population consisting principally of intravenous drug abusers with suspected acquired immunodeficiency syndrome. | generalized lymphadenopathy in intravenous drug abusers (ivdas) at risk for aids has not been well studied. we have retrospectively analyzed the results of lymph node biopsies obtained from 27 patients referred to the infectious diseases service for evaluation of generalized lymphadenopathy and suspected aids during a recent 18-month period. fourteen of the patients were heterosexual ivdas, 7 were male homosexual ivdas, and 6 were male homosexual non-ivdas. all of the patients were residents of ... | 1988 | 3144197 |
| minimal inhibitory concentrations of isoniazid, rifampin, ethambutol, and streptomycin against mycobacterium tuberculosis strains isolated before treatment of patients in taiwan. | minimal inhibitory concentrations (mics) of isoniazid (inh), rifampin (rmp), ethambutol (emb), and streptomycin (sm) for susceptible "wild" m. tuberculosis strains isolated from taiwanese patients were within the limits previously reported for strains isolated in the united states. the highest agar-determined mics (in 7h10 and 7h11 agar) corresponded well with the critical concentrations established for these media. the highest mics found radiometrically in 7h12 broth were significantly lower th ... | 1988 | 3144210 |
| research initiatives in the immunology of tuberculosis. american thoracic society committee on priorities for tuberculosis research. | | 1988 | 3144215 |
| the results of 9-month isoniazid-rifampin therapy for pulmonary tuberculosis under program conditions in san francisco. | the outcome of treatment for pulmonary tuberculosis using isoniazid and rifampin for 9 months supplemented by ethambutol for the initial 2 months was evaluated in a cohort of 233 patients. all patients had sputum cultures positive for mycobacterium tuberculosis sensitive to isoniazid and rifampin. of the 233 patients, 200 completed the regimen without change. four patients had adverse reactions necessitating discontinuation and four became pregnant and had ethambutol substituted for rifampin. al ... | 1988 | 3144221 |
| efficacy of two mycobacterial antigen preparations in the serodiagnosis of tuberculosis by enzyme-linked immunosorbent assay. | | 1988 | 3144261 |
| comparative in-vitro activity of fleroxacin and other 6-fluoroquinolones against mycobacteria. | the susceptibility of 11 clinical isolates of mycobacterium tuberculosis, 3 m. kansasii, 3 m. xenopi, 2 m. scrofulaceum, 2 m. marinum, 2 m. malmoense to fleroxacin, ciprofloxacin, norfloxacin, rifampicin, isoniazid, ethambutol, and streptomycin was determined by the standard proportion method (middlebrook 7h10 agar). all m. tuberculosis, m. kansasii, m. xenopi, m. scrofulaceum, m. marinum, and m, malmoense isolates including those resistant to conventional antimycobacterials were inhibited by 0. ... | 1988 | 3144550 |
| tuberculous ulcer of the skin. | a case of tuberculous skin ulcer is reported. the biopsy specimen did not reveal acid-fast bacteria but cultures grew mycobacterium tuberculosis. a high index of suspicion is needed to diagnose mycobacterial ulcers correctly. the classification of the cutaneous tuberculoses is discussed. | 1988 | 3144560 |
| antibiotic prophylaxis after exposure to antibiotic-resistant mycobacterium tuberculosis. | | 1988 | 3144726 |
| [tuberculous meningitis]. | | 1988 | 3144783 |
| lupus vulgaris with numerous tubercle bacilli. | | 1988 | 3145160 |
| [isolation of mycobacteria from clinical specimens during the last decade]. | | 1988 | 3145346 |
| [mycobacterioses in aids. autopsy and clinical findings]. | | 1988 | 3145496 |
| [use of ethambutol in higher and regular doses in the treatment of patients with chronic destructive forms of pulmonary tuberculosis]. | | 1988 | 3145497 |
| [experience with practical use of a complex of 3 nutrient media for culture of mycobacterium tuberculosis]. | | 1988 | 3145498 |
| role of broncho-alveolar lavage in the diagnosis of pulmonary disease. | | 1987 | 3145728 |
| laboratory isolation of mycobacteria tuberculosis in kenya. | | 1988 | 3145852 |
| high prevalence of tuberculosis in aids patients in spain. | a total of 67 cases of tuberculosis was diagnosed in the first 100 cases of aids, diagnosed according to the former cdc criteria, at a hospital in madrid, spain. this is the highest known prevalence of tuberculosis in aids patients both within and outside spain. the clinical manifestations of tuberculosis were very variable and atypical. the rate of isolation of mycobacterium tuberculosis from blood was particularly high: of 25 patients in whom blood cultures were performed, 16 were positive. in ... | 1988 | 3145865 |
| [a method of preservation of pathological specimens for detection of mycobacterium tuberculosis in tissue culture]. | | 1988 | 3146063 |
| [radioimmunologic and immunoenzyme methods of analysis of anti-tuberculosis antibodies]. | | 1988 | 3146064 |
| [bronchial aspirate in the diagnosis of pulmonary tuberculosis]. | | 1988 | 3146110 |
| [distribution of bacteriophage types of mycobacterium tuberculosis in france]. | the bacteriophage typing of m. tuberculosis enables separation of the strains of the species according to their sensitivity to certain bacteriophages. a relationship has been observed between the geographical origin of patients and the distribution of the phage types of their strains. this study related to a sample of 450 strains isolated between 1978 and 1987 in patients of french origin coming from different regions in france. an analysis of the data provided by the study indicates that the di ... | 1988 | 3146114 |
| [production of and response to interleukin-2 by peripheral mononuclear cells of patients infected with mycobacterium tuberculosis]. | | 1988 | 3146121 |
| identification of mycobacterium bovis isolates using a monoclonal antibody. | a rapid immunoperoxidase slide assay for the identification of mycobacterium bovis culture isolates is described. the monoclonal antibody used in this assay is specific for the m. tuberculosis complex of organisms. all m. bovis isolates tested, including 151 separate field isolates of m. bovis were positive as were 11 out of 12 m. tuberculosis strains and 4 out of 6 bacillus calmette guerin (bcg) strains. one strain each of m. africanum and m. microti was negative. this assay provides a consider ... | 1988 | 3146158 |
| [evaluation of the extent of massive bacterial elimination in newly detected patients with destructive pulmonary tuberculosis]. | | 1988 | 3146162 |
| [respiratory pathogens in chronic obstructive pulmonary disease in the guangzhou area]. | | 1988 | 3146442 |
| mycobacterial species responsible for tuberculosis and mycobacteriosis cases in the czech socialist republic, 1981-1985. | this study is based on the analysis of nation-wide notification data on the bacteriologically proved mycobacterial infections registered in the national information system on bacillary tuberculosis. over the 5-year period under study, as many as 2,226 m. tuberculosis isolations were on average reported annually in the country (i.e. 21.6 per 100,000 population), and of these 62.5% were isolations in males, 63.5% were repeated isolations and 87% were isolations from sputum specimens; identificatio ... | 1988 | 3146598 |
| repetitive dna sequence of mycobacterium tuberculosis: analysis of differential hybridization pattern with other mycobacteria. | in order to generate specific dna probes for mycobacterium tuberculosis, restriction fragment length analysis was carried out with some of the mycobacterial species that fall within the tuberculosis complex. the presence of specific bands of 5.6 kb and 4.8 kb was revealed in the alui dna digest of m. tuberculosis. the hybridization profile of the 5.6-kb alui dna sequence, as judged by the southern blot and dot blot hybridization experiments, revealed the presence of this sequence in m. tuberculo ... | 1988 | 3146611 |
| [chemotherapy of newly detected cases of pulmonary tuberculosis prior to the results of determining the drug sensitivity of mycobacterium tuberculosis]. | | 1988 | 3146752 |
| purified protein derivative (ppd). | | 1988 | 3146815 |
| the role of t cell--macrophage interactions in tuberculosis. | acquired resistance against tuberculosis paradigmatically depends on specific t lymphocytes and mononuclear phagocytes. the etiological agent, mycobacterium tuberculosis is capable of replicating in mononuclear phagocytes which act both as habitat and as effectors of protection. upon interaction with antigen-specific t lymphocytes infected mononuclear phagocytes acquire tuberculostatic activities. here, data from experimental tuberculosis studies in mice are summarized which show that: interleuk ... | 1988 | 3146818 |
| poetry: the doctor and the tubercle bacilli. | | 1988 | 3146995 |
| application of rapid methods (bactec system) in clinical mycobacteriology and in the search for new drugs. | | 1988 | 3146996 |
| evaluation of the quality of bacteriologic methods used to diagnose tuberculosis in argentina. | | 1988 | 3147118 |
| the inhibitory effects of mycobacterial lipoarabinomannan and polysaccharides upon polyclonal and monoclonal human t cell proliferation. | lipoarabinomannan from mycobacterium tuberculosis was able to inhibit antigen induced t cell proliferation of human cd4+ t cell clones specific for influenza virus. the inhibitory effect was also present when peripheral human t cells were stimulated with crude mycobacterial antigen extracts. non-specific t cell stimulation, i.e. il-2, pha and anti-cd3 antibodies coupled to beads, was not affected. the inhibitory property was also found when arabinomannan and arabinogalactan of mycobacterial orig ... | 1988 | 3147152 |
| antibody levels to mycobacteria in relation to hla type: evidence for non-hla-linked high levels of antibody to the 65 kd heat shock protein of m. bovis in rheumatoid arthritis. | we previously reported dr2 and dr7-associated regulation of antibody binding to mycobacteria in rheumatoid arthritis sera (ra), but not in tuberculosis (tb). an extensive analysis of antibody to mycobacteria in matched normal sera, in relation to both hla class i and class ii has revealed no class ii correlations, confirming that the original findings were due to ra. there was however a very strong association between igm binding to m. tuberculosis and cw1 (p = 0.0004). ra patients have striking ... | 1988 | 3147153 |
| identification of mycobacterium tuberculosis in sputum by direct inoculation of the bactec nap vial. | the mycobacterium tuberculosis complex (m. tuberculosis, m. bovis, and m. africanum) can be differentiated from mycobacteria other than m. tuberculosis (mott bacilli) with the bactec nap test (johnston laboratories, becton, dickinson & co., towson, md), by selectively inhibiting their growth with p-nitro-alpha-acetyl-amino-beta-hydroxypropriophenone (nap). the bactec nap test is recommended for isolated mycobacterial cultures. in this report, a direct nap test is performed by immediate inoculati ... | 1988 | 3147161 |
| the antibacterial activity of a new 3-azinomethyl-rifamycin. | the new 3-azinomethyl-rifamycin, spa-s-565, was shown to exert an effective antibacterial activity in vitro comparable to that of rifampicin. in fact, the antibacterial activity of spa-s-565 against numerous gram-positive cocci belonging to staphylococcus and streptococcus species as well as against 20 strains of mycobacterium tuberculosis, was similar to that of rifampicin. in swiss albino mice intraperitoneally infected with staphylococcus aureus oxford strain or streptococcus pyogenes, the pr ... | 1988 | 3147199 |
| isolation of recombinant mycobacterial antigens by an automatic and generally applicable purification method for beta-galactosidase fusion proteins. | an automated two-dimensional chromatographic method has been developed for the isolation and concentration of recombinant fusion proteins with beta-galactosidase. the system consists of an immunoaffinity column with anti-beta-galactosidase antibodies as ligand, followed by an anion-exchange column. it was used for the purification and concentration of recombinant fusion proteins from mycobacterium tuberculosis and m. leprae. small amounts of crude lysates of escherichia coli were loaded stepwise ... | 1988 | 3147285 |
| [value of bronchoscopic examination in the diagnosis of diseases of the respiratory system. i. neoplasms of the respiratory tract and tuberculosis]. | | 1988 | 3147496 |
| [the laboratorio nacional de referencia de mycobacteria y tuberculosis in the antituberculosis campaign in cuba]. | | 1988 | 3147500 |
| the role of cachectin/tnf in the pathogenesis of tuberculosis. | the presence of cachectin or tumor necrosis factor (tnf) associated with hypertriglyceridemia was demonstrated in the serum of patients with pulmonary tuberculosis. the hyperlipidemia that accompanies this infection may be mediated by the tnf inhibition of lipoprotein lipase activity. this sequence of events may be sufficient to explain, in part, the complex metabolic changes and emaciation observed in tuberculosis patients. | 1988 | 3147796 |
| [uses of determination on igg-antibody against mycobacterial antigens for the diagnosis in pulmonary tuberculosis]. | | 1988 | 3147815 |
| [some aspects of refractory pulmonary tuberculosis]. | | 1988 | 3147816 |
| fibreoptic bronchoscopy in smear-negative pulmonary tuberculosis. | fifty smear-negative pulmonary tuberculosis patients underwent fibreoptic bronchoscopy. bronchial aspirate smears of twelve patients and post-bronchoscopic sputum smears of fourteen patients were positive for acid-fast bacilli (afb). bronchial biopsy provided the diagnosis in 9 out of 30 patients. brush smears were positive in 28 patients, being the only positive sample in ten cases. a high yield from brush smears was obtained due to their preparation from caseous material wherever visible in th ... | 1988 | 3147911 |
| intraspecies differentiation of strains of mycobacterium tuberculosis obtained from czechoslovakian, mongolian and south indian patients. | | 1988 | 3147942 |
| drug resistance of mycobacterium tuberculosis isolated from sputum in manipal. | | 1988 | 3147943 |
| bacteriological status of notified tuberculosis cases in the republic of ireland 1982-85. | | 1988 | 3147969 |
| [dynamics of the frequency of development of drug resistance in the causative agent of tuberculosis and its effect on the efficacy of treatment of patients with pulmonary tuberculosis]. | | 1988 | 3148132 |
| [use of 3h-thymidine to study the metabolism of mycobacterium tuberculosis as changed during chemotherapy]. | | 1988 | 3148133 |
| [results of the repeated effect of low-energy laser radiation on mycobacterium tuberculosis]. | | 1988 | 3148134 |
| [indicators of antibody formation in patients with pulmonary tuberculosis and drug-resistant mycobacteria]. | | 1988 | 3148135 |
| [current theories on the pathogenesis of tuberculosis (lecture)]. | | 1988 | 3148136 |
| [evaluation of csf mycobacterium tuberculosis antigen 5 and its antibody detection in the diagnosis of tuberculous meningitis]. | | 1988 | 3148371 |
| repetitive dna sequences as probes for mycobacterium tuberculosis. | three cloned segments of mycobacterium tuberculosis dna which are promising as clinical probes were identified. an mboi digest of dna from a clinical isolate of m. tuberculosis was cloned into bacteriophage m13. to identify recombinants specific for the m. tuberculosis complex, plaque lifts were hybridized with m. bovis and m. kansasii dna. recombinants which selectively hybridized with m. bovis dna were characterized by probing slot blots and restriction digests of dna from various mycobacteria ... | 1988 | 3148630 |
| [studies on pyrazine derivatives. xxii. synthesis and tuberculostatic activity of the products of reactions of pyrazinyl-1,3,4-oxadiazol-2-thione with amines]. | | 1988 | 3149138 |
| [synthesis of 1,3,4-thiadiazole derivatives with potential tuberculostatic action]. | | 1988 | 3149139 |
| an experimental model of chemotherapy on dormant tuberculous infection, with particular reference to rifampicin. | mice were infected intravenously with a streptomycin (sm)-dependent strain of tubercle bacilli which had been starved of the antibiotic. the inoculum persisted in the spleen for a fairly long period, especially keeping almost the initial level of viable counts in the first few weeks. isoniazid (inh) administration exerted little effect on such fate of the infection at a bactericidal dose to the same strain multiplying under the supply of sm. rifampicin (rfp) was, however, highly effective in eit ... | 1988 | 3149354 |
| [modified fin-ii medium for improving the bacteriological diagnosis of tuberculosis]. | | 1988 | 3149430 |
| induction and regulation of cytotoxic t cells by microbial antigens and recombinant interleukin 2. | the proliferation and development of cytotoxic t cells was investigated in human peripheral blood mononuclear cell (pbmc) cultures stimulated with an antigenic extract from candida albicans (mpps), or with the purified protein derivative from mycobacterium tuberculosis (ppd), or with human recombinant interleukin 2 (ril-2). microbial antigen- and ril-2-induced cytotoxic t cells were able to lyse both natural killer (nk) sensitive and resistant targets. no correlation was observed between the dev ... | 1988 | 3149595 |
| [alteration of permeability of bacterial envelope barrier in rifamdin-resistant mycobacterium tuberculosis]. | | 1988 | 3149620 |
| in-vitro susceptibility of mycobacterium tuberculosis, mycobacterium bovis and mycobacterium kansasii to amoxycillin and ticarcillin in combination with clavulanic acid. | the in-vitro susceptibility of mycobacterium tuberculosis, m. bovis, and m. kansasii to amoxycillin alone and in combination with 2 mg/l of clavulanic acid was evaluated by broth dilution. the mic90 of amoxycillin plus clavulanic acid was 4 mg/l compared with greater than 32 mg/l for amoxycillin alone when tested against m. tuberculosis (n = 27). m. bovis (n = 8) was the most susceptible species with an mic90 of amoxycillin 8 mg/l, compared with 0.5 mg/l for the combination. m. kansasii (n = 6), ... | 1988 | 3149633 |
| the organization of laboratory services for a "tuberculosis control programme". | | 1988 | 3149687 |
| theoretical and experimental aspects of the host-parasite-drug relationship in tuberculosis chemotherapy. | | 1988 | 3149697 |
| serum antibody responses to mycobacteria in leprosy patients and their contacts. | | 1988 | 3149706 |
| [ways of increasing isolation and growth of mycobacterium tuberculosis in modified finn-ii media]. | | 1988 | 3149741 |
| [antitubercular agents. 42. dithiooxamides, a new group of potential antitubercular agents]. | | 1988 | 3149749 |
| [synthesis and antimycobacterial action of lipophilic substituted 2,4-diamino-5-benzylpyrimidines]. | 2,4-diamino-5-benzylpyrimidines 1-23 with lipophilic substitution in the benzylic moiety were synthesized by the morpholino-anilino-procedure. their effects against various mycobacteria were verified by mic (minimum inhibitory concentration) in whole cells and i50-measurements in whole cell and cell-free systems. especially the substances 7-12 are strong inhibitors of some atypical mycobacterial strains which are sometimes associated with tuberculosis in the elderly and with aids. they might be ... | 1988 | 3149896 |
| [biological side-effects of potential anti-tubercular agents. xiv. relation between the chemical structure, antitubercular activity and hepatotoxicity of 2-alkylthio-6-(2-chlorobenzamido) benzothiazoles]. | | 1988 | 3149912 |
| [the detection of mycobacterial antigens in cerebrospinal fluid by the enzyme-linked immunosorbent assay]. | | 1988 | 3149930 |
| distribution of phthiocerol diester, phenolic mycosides and related compounds in mycobacteria. | among 28 mycobacterial species studied, only mycobacterium tuberculosis, m. bovis, m. africanum, m. marinum, m. kansasii, m. gastri and m. ulcerans produced waxes yielding long-chain beta-diol components (called phthiocerol and companions) and polymethyl-branched fatty acids on saponification. the same mycobacterial species also produced diesters of phenol phthiocerol and companions. fatty acids esterifying these fatty alcohols in m. marinum and m. ulcerans were found to belong to the phthiocera ... | 1988 | 3149973 |
| [mycobacterium avium complex bacteria probably live longer than other slowly growing mycobacteria]. | | 1988 | 3150021 |
| [something new about an old acquaintance: the tuberculous bacillus]. | | 1988 | 3150031 |
| [antitubercular agents. 44. n,n-dialkyldithiooxamide]. | | 1988 | 3150060 |
| [studies of pyrazine derivatives. xxv. synthesis and the tuberculostatic activity of the products of reaction of 5-(6-methoxy- and 5-(6 morpholinopyrazinyl)-1,3,4-oxadiazol-2-thione with amines]. | | 1988 | 3150245 |
| [drug susceptibility test of mycobacteria]. | | 1988 | 3150470 |
| [comparison of growth of mycobacteria in commercially available dubos tween--albumin liquid media]. | | 1988 | 3150482 |
| [isolated subcutaneous abscesses caused by tuberculosis]. | | 1988 | 3150851 |
| [use of gas chromatography in the detection of m. tuberculosis]. | | 1988 | 3150857 |
| in vitro activity of antimicrobial agents against mycobacteria. | the aims of this study were to investigate the possible effects of new antimicrobial agents, the conventional antituberculosis drugs and several combinations of these agents against 190 clinical isolates of mycobacterium tuberculosis and 30 of m. avium. | 1988 | 3150951 |
| structure and molecular species composition of three homologous series of alpha-mycolic acids from mycobacterium spp. | three homologous series of alpha-mycolic acids (dicyclopropanoyl acids, monocyclopropanoyl monoenoic acids and dienoic acids) from 16 rapidly growing and 14 slowly growing mycobacteria were separated by argentation thin-layer chromatography and analysed by gas chromatography/mass spectrometry of their trimethylsilyl ether derivatives. mycobacterial species were separated into five groups. strains of group a contained similar amounts of even and odd carbon-numbered dienoic acids, with a methyl br ... | 1988 | 3150979 |
| mycobacterium tuberculosis antigen specific human t-cell lines are cytolytic to autologous antigen pulsed macrophages. | | 1988 | 3151038 |
| [usefulness of bacteriologic examination of specimens obtained by fine-needle aspiration biopsy of the lungs in the diagnosis of tuberculosis]. | | 1988 | 3151123 |
| [difficulties in the diagnosis of tuberculosis]. | | 1988 | 3151124 |
| in vitro activity of ciprofloxacin in combination with standard antituberculous drugs against mycobacterium tuberculosis. | chequer-board titrations show that the in vitro activity of ciprofloxacin against mycobacterium tuberculosis is independent of that of streptomycin, isoniazid, ethambutol and pyrazinamide and confirm that there is antagonism between ciprofloxacin and rifampicin. | 1988 | 3151140 |
| a competition elisa for the detection of mycobacterial antigen in tuberculosis exudates. | an enzyme-linked immunosorbent assay (elisa) was designed to detect the inhibition of bcg-anti-bcg reactions by soluble antigens of mycobacterium tuberculosis. eighty-four samples were tested of which 59 were of cerebrospinal fluid (csf) (25 control, 10 bacterial, 14 viral and 10 tuberculous meningitis); and twenty-five were of pleural or ascitic fluid (15 tuberculous exudates and 10 non-tuberculous samples). a statistically significant difference (p less than 0.01) was found between the tubercu ... | 1988 | 3151141 |
| a comparison of the use of pipettes and loops for the inoculation of mycobacterium tuberculosis onto media. | | 1988 | 3151142 |
| metabolism in mycobacterium leprae, m. tuberculosis and other pathogenic mycobacteria. | | 1988 | 3151445 |