| genetic homogeneity of goat malaria parasites in asia and africa suggests their expansion with domestic goat host. | plasmodium was first identified in a goat in angola in 1923, and only recently characterized by dna isolation from a goat blood sample in zambia. goats were first domesticated in the fertile crescent approximately 10,000 years ago, and are now globally distributed. it is not known if the plasmodium identified in african goats originated from parasites circulating in the local ungulates, or if it co-evolved in the goat before its domestication. to address this question, we performed pcr-based sur ... | 2018 | 29643434 |
| integrative analysis reveals ncrna-mediated molecular regulatory network driving secondary hair follicle regression in cashmere goats. | cashmere is a keratinized product derived from the secondary hair follicles (shfs) of cashmere goat skins. the cashmere fiber stops growing following the transition from the actively proliferating anagen stage to the apoptosis-driven catagen stage. however, little is known regarding the molecular mechanisms responsible for the occurrence of apoptosis in shfs, especially as pertains to the role of non-coding rnas (ncrnas) and their interactions with other molecules. hair follicle (hf) degeneratio ... | 2018 | 29587631 |
| genome-wide association mapping for type and mammary health traits in french dairy goats identifies a pleiotropic region on chromosome 19 in the saanen breed. | type traits and mammary health traits are important to dairy ruminant breeding because they influence animal health, milking ability, and longevity, as well as the economic sustainability of farms. the availability of the genomic sequence and a single nucleotide polymorphism chip in goats has opened up new fields of investigation to better understand the genes and mechanisms that underlie such complex traits and to be able to select them. our objective was to perform a genome-wide association st ... | 2018 | 29573797 |
| scrotal ablation and orchiectomy in the domestic laboratory goat (capra hircus). | domestic goats (capra hircus) have been used as animal models in biomedical research, and for numerous years for agricultural research and models for human diseases. this column describes an improved surgical technique, for castration of male goats, similar to companion animal techniques for use in the laboratory setting. the technique discussed supports a more in-depth perioperative protocol for performing scrotal ablation and orchiectomy in the male goat. | 2018 | 32734042 |
| morphological and molecular characterization of three eimeria species from captured rangeland goats in western australia. | faecal shedding of eimeria by captured rangeland goats (capra hircus) was investigated using a longitudinal observational study. faecal samples were collected from 125 male goats on four occasions. the first sampling occurred following capture and transport, immediately after arrival at a commercial goat depot (feedlot) in western australia, with subsequent 3 sample collections occurring at one month intervals thereafter. goats were composite breed and aged approximately 9-12months on arrival at ... | 2017 | 31014847 |
| care in the community? interpretations of a fractured goat bone from neolithic jarmo, iraq. | a case study of a goat metatarsal exhibiting a complex diaphyseal fracture from pottery neolithic jarmo in the central zagros region of the eastern fertile crescent is here described and analysed. the central zagros is one of the areas with the earliest evidence for goat domestication. the significance of the pathology may be viewed within the context of domestic goat ecology in the landscape of jarmo, potentially impacting browsing behaviour (goats raise themselves on their hind limbs to browse ... | 2014 | 29539488 |
| mammary intraductal carcinoma in goats ( capra hircus). | three intraductal carcinomas were found in the mammary glands of 220 goats. the affected glands were indurated and had multiple grey-white dots resembling areas of suppuration on their cut surfaces. the growths were multicentric and had diffuse intraluminal proliferation of cells, giving laciform, cribriform or solid appearance to the epithelium. in one, the neoplastic cells were invasive, having overcome the myoepithelial basement membrane complex, and had metastasised to the regional lymph nod ... | 1972 | 29883991 |
| evaluating angiotensin-converting enzyme 2-mediated sars-cov-2 entry across species. | the severe acute respiratory syndrome coronavirus 2 (sars-cov-2) pandemic represents a global threat, and the interaction between the virus and angiotensin-converting enzyme 2 (ace2), the primary entry receptor for sars-cov-2, is a key determinant of the range of hosts that can be infected by the virus. however, the mechanisms underpinning ace2-mediated viral entry across species remains unclear. using infection assay, we evaluated sars-cov-2 entry mediated by ace2 of 11 different animal species ... | 2021 | 33610551 |
| structural analysis of covid-19 spike protein in recognizing the ace2 receptor of different mammalian species and its susceptibility to viral infection. | the pandemic covid-19 was caused by a novel coronavirus-2 (sars-cov-2) that infects humans through the binding of glycosylated sars-cov-2 spike 2 protein to the glycosylated ace2 receptor. the spike 2 protein recognizes the n-terminal helices of the glycosylated metalloprotease domain in the human ace2 receptor. to understand the susceptibility of animals for infection and transmission, we did sequence and structure-based molecular interaction analysis of 16 ace2 receptors from different mammali ... | 2021 | 33552834 |
| evidence of transmission of goatpox between domestic goats and wild himalayan goral (naemorhedus goral) in arunachal pradesh, india. | examination of carcasses of himalayan goral (naemorhedus goral) revealed nodular, pox-like eruptions in the skin. similar disease was also seen in domestic goats (capra aegagrus hircus) in the same area. goatpox virus was identified as the etiology of the disease in both cases, with probable transmission between the species. | 2021 | 33822163 |
| gene expression profile in peripheral blood nuclear cells of small ruminant lentivirus-seropositive and seronegative dairy goats in their first lactation. | the immune response to a viral antigen causes inflammatory cell infiltration to the tissue, which creates a suitable environment for the replication of the virus in macrophages, and the recruitment of more monocytes to the site of infection, or latently infected monocytes. the aim of the study was to analyze the transcriptomic profile of peripheral blood nuclear cells isolated from srlv-seropositive and srlv-negative goats at the peak of their first lactation. srlv-seropositive goats were probab ... | 2021 | 33810360 |