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vaccination against diseases associated with herpesvirus infections in animals: a review.an account is presented of the development and use of herpesvirus vaccines in domestic animals, with particular reference to those viruses causing cytolytic rather than oncogenic infections. the chief infections covered are aujeszky's disease (ad or pseudorabies), infectious bovine rhinotracheitis (ibr) and equine rhinopneumonitis (equine abortion; ehv-1). others mentioned are feline viral rhinotracheitis and malignant catarrhal fever of cattle. both live-modified and inactivated vaccines are wi ...1978221416
hypocomplementemia associated with naturally occurring lymphosarcoma in pet cats.eighty cats were classified by indirect immunofluorescence and histologic diagnosis into four categories: normal, feline leukemia virus (felv) infected; normal noninfected; lymphosarcoma-felv infected; lymphosarcoma, no felv present. all viremic cats with lymphosarcoma were found to be hypocomplementemic and activation of the complement system had occurred via the classical pathway. sera of cats with lymphosarcoma in the absence of felv had varying levels of total hemolytic complement (tch50) ra ...1979221581
enzyme immunoassay for feline oncornavirus-associated cell membrane antigen (focma) and detection of focma in cell extract by enzyme immunoassay inhibition test.an enzyme immunoassay (eia) for focma has been developed. the assay uses alkaline phosphatase-conjugated rabbit anti-cat igg as the second antibody and p-nitrophenyl phosphate as the substrate for the enzyme to detect cat focma antibody bound to the target cells. in comparison with the indirect immunofluorescence (iif) test, which was originally used for focma assay, our results showed a good correlation between the two methods. the eia gives a more objective measure of focma reactivity than doe ...1979221593
[regulation of pituitary hormone secretion: regulation of acth secretion]. 1979221705
[selective inhibition of hypoxic pulmonary vasoconstriction by inhibition of cytochrome oxidase (author's transl)]. 1979221712
stimulatory effect of vanadate on (na+ + k+)-atpase activity and on 3h-ouabain-binding in a cat heart cell membrane preparation. 1979221820
negative and positive inotropic action of vanadate on atrial and ventricular myocardium. 1979221827
sleep state effects on breathing after spinal cord transection and vagotomy in the cat.the role of chest wall and vagal afferents on breathing during wakefulness (w), nonrapid eye movement sleep (nrem), and rem sleep was assessed in 16 adult cats implanted with electrodes and skull bolts for sleep recordings with head restraint. breathing was monitored with a pneumotachograph. following control recordings establishing characteristic respiratory patterns during each state, cats sustained spinal cord transections at t-1, vagotomies, or both. the transections decreased variability of ...1979221965
[effect of streptomycin on synaptic transmission in the auditory area of the cerebral cortex]. 1979222034
a rotavirus from kittens. 1979222038
an analgesic action of intranvenously administered lidocaine on dorsal-horn neurons responding to noxious thermal stimulation.using extracellular single-unit recording techniques, effects of intravenously administered lidocaine on dorsal-horn nociceptive neurons were studied in cats made decerebrate whose spinal cords had been transected. thirty-seven neurons in rexed lamina v responding to high-threshold mechanical and noxious thermal stimuli (radiant heat, using hardy-wolff-goodell dolorimeter) were studied. lidocaine hydrochloride, 2.5, 5, and 10 mg/kg, iv, produced dose-related suppression of both spontaneous activ ...1979222173
a theory for the acquisition and loss of neuron specificity in visual cortex.we assume that between lateral geniculate and visual cortical cells there exist labile synapses that modify themselves in a new fashion called threshold passive modification and in addition, non-labile synapses that contain permanent information. in the theory which results there is an increase in the specificity of response of a cortical cell when it is exposed to stimuli due to normal patterned visual experience. non-patterned input, such as might be expected when an animal is dark-reared or r ...1979222355
cross correlation analysis of 40 hz activity in the sigmoid gyrus, nucleus accumbens and amygdala. 1979222375
[horseradish peroxidase-labeled cells as sources of the spinoreticular and spinothalamic systems of the brain].the cells of spinoreticular and spinothalamic fibrous systems of the cat brain were studied by the method of axone transmission of horse-radish peroxidase (hp). a dense accumulation of hp-labeled neurons establishing direct relations with the reticular formation and thalamus was seen in the upper segments of the spinal cord. in the lower segments these zones were confined to the medial part of the ventral horn and the intermediate zone of the gray matter. the neurons established direct connectio ...1979222379
the effects of methionine- and leucine-enkephalin on spinal neurones of the cat.extra- and intracellular recordings were obtained from physiologically identified, spinal neurones in the 6th and 7th lumbar segments of the pentobarbitone-anaesthetized cat. microiontophoretically applied methionine- and leucine-enkephalin reversibly inhibited the spontaneous, synaptically induced, and l-glutamate-induced activity in the majority of dorsal horn neurones studied in laminae 4, 5 and 6 of rexed. most of these depressant effects were antagonized by the prior microiontophoretic appl ...1979222394
the antagonism of amino acid-induced excitation of spinal neurones in the cat.dl-alpha-aminoadipate (dlalphaaa) and l-glutamic acid diethylester (gdee) were compared as antagonists of the excitatory effects of a number of amino acids on interneurones, and also of acetylcholine on renshaw cells of the cat spinal cord. the excitants could be ranked in order of their sensitivity of the two antagonists. ibotenate and the optical isomers of n-methylaspartate were the most readily antagonised by dlalphaaa and the least by gdee; l-glutamate and quisqualate were most affected by ...1979222399
some effects of short-term methylprednisolone therapy in normal cats.four normal cats were treated weekly for 4 weeks with repositol methylprednisolone. hemograms, serum chemistry panels, urinalyses, 24 hour water consumption, physical and constitutional parameters, and blood cortisol responses to acth stimulation were monitored before and during a day were done prior to steroid therapy on each cat. clinicopathologic abnormalities induced by steroid therapy were, on the whole, inconsistent and minor. the most important findings were: (1) marked steroid-induced su ...1979222534
[methylprednisolone-induced inhibition of the sympathetic vasomotor tonus in hemorrhagic shock].in anesthetized cats massive doses of methylprednisolon (40 mg/kg body wt.) induce a blood pressure decrease with bradycardia, which is not transmitted through vagal efferents. these effects are due to an inhibition of sympathetic outflow to heart and vessels.1978222554
modification by sq 14225 of blood pressure and adrenal catecholamine response to hemorrhage.sq 14225 infusion to cats exposed to hemorrhage suppressed adrenomedullary catecholamine release. the immediate compensatory blood pressure response was unaffected, while the later compensatory response was of a higher magnitude in intact cats that in sq 14225-treated animals. adrenal gland blood flow was better preserved in sq 14225-treated hemorrhaged cats than in cats exposed to hemorrhage only. these data emphasize the role of angiotensin ii in adrenal catecholamine and blood pressure respo ...1979222597
[heart rate in cats during sleep after coagulation of the locus coeruleus].the relationship between heart rate (hr) modulation and sleep mechanisms were analysed in 14 unrestrained cats with implanted electrodes and additional tripolar electrodes in the lateral geniculate nucleus and the abducens nucleus for recording the ponto--geniculo--occipital spikes. anterior lesion of the locus coeruleus (lc) reduced the heart rate by about 18%, and a severe arrhythmia with augmented dispersion of r--r intervals occurred during paradoxical sleep (ps). cats with posterior lesion ...1979222625
effects of dihydroergotoxine (redergine) on the sleep-wakefulness cycle in the cat.investigations with dihydroergotoxine (dhe 1.0; 3.0 and 5.0 mg/kg i.p.) indicate that dhe exerts effect on the sleep-wakefulness cycle of the cat. in doses of 3.0 and 5.0 mg/kg i.p. dhe has a suppressant effect on sleep, and in particular on rem sleep, while wakefulness was increased. with a dose of 1.0 mg/kg, wakefulness and rem sleep were decreased, while slow-wave sleep was increased.1979222649
endogenous rd-114 virus of cats: absence of antibodies to rd-114 envelope antigens in cats naturally exposed to feline leukemia virus.healthy cats, including those exposed to feline leukemia virus in leukemia cluster households, lack evidence of humoral immunity to virion surface antigens of the endogenous rd-114 virus.1979222681
some observations on the phosphatase cytochemistry of the submandibular gland of cat.the localization of reaction product arising from incubation with thiamine pyrophosphate at ph 7.2 and beta-glycerophosphate or nitrophenylphosphate at ph 5 has been examined in central and demilunar acinar cells, myoepithelial cells, and cells of the striated ducts. thiamine pyrophosphate reaction product was seen in the inner saccules of the golgi apparatuses of the different types of cell. beta-glycerophosphate and nitrophenylphosphate reaction products were seen in lysosomes, and in gerl-lik ...1979222714
the dose response of cats to experimental infection with feline viral rhinotracheitis virus. 1979222816
the beta-adrenergic responses in isolated splenic capsule area of several species of animals.in isolated splenic capsules of mouse, rat, guinea pig, rabbit, cat and dog, either a single or a cumulative dose of l- and dl-isoproterenol at a concentration higher than l0(-9) m, induced a relaxation which was inhibited or blocked with pretreatment of 10(-5) m propranolol. at a concentration of 5 x 10(-6) m to 10(-5) m 1- and dl-isoproterenol, an inverse contraction was induced, and such response was prevented or reversed to one of relaxation in the presence of 10(-5) m phentolamine. applicat ...1979222923
diagnostic exercise. cerebellar ataxia. 1979222957
secretory granules of the duodenal enterochromaffin cells of the cat. 1979222959
[effectivess of synaptic influences of the ascending tracts of different spinal cord funiculi on reticulospinal neurons in cats].extracellular recording of the responses of the reticulospinal neurons evoked by stimulation of the dorsal, dorsolateral, ventral and ventrolateral spinal funiculi were performed in cats under chloralose anesthesia. it is found that dorsal funiculi of the spinal cord are an effective source of ascending influences on the reticulospinal neurons. correlation of synaptic responses of the reticulospinal neurons with antidromatic responses in the peripheral nerves set up by stimulation of the dorsal ...1979223075
the effects of intranigral injections of picrotoxin and carbachol in cats with a lesioned nigrostriatal pathway.picrotoxin, carbachol and atropine were injected intranigrally through chronically implanted crannulae in cats. the drug-induced behavioural syndromes, mainly asymmetric behaviour, were analyzed. the changes in these syndromes after 6-hydroxydopamine (6-ohda) lesion of the substantia nigra (sn) indicate that, in addition to the dopaminergic (da), a non-catecholaminergic (non-ca) nigral output exists, both being responsible for asymmetric behaviour. it is further suggested that gamma-aminobutyric ...1979223087
inhibition of the spinal transmission of nociceptive information by supraspinal stimulation in the cat.in cats anaesthetized with alpha-chloralose or sodium pentobarbitone a study was made of the effects of supraspinal electrical stimulation on the excitation of dorsal horn neurones by noxious and non-noxious cutaneous stimuli. stimulation near the dorsal raphe of the midbrain non-selectively reduced the responses of neurones to both noxious and non-noxious stimuli. intravenous naloxone (0.3-0.6 mg/kg) had no effect on this inhibition. electrical stimulation near the medullary raphe selectively r ...1979223105
the effect of glucagon, dibutyrylic cyclic amp and theophylline on bile production in the cat.the effect of glucagon, dibutyrylic cyclic amp and theophylline on bile production and liver metabolism was studied in fasting, chloralose anesthetized cats. after 45 min infusion of glucagon (0.1 mug/kg/min) total bile flow started to increase and finally reached a level 32% above control bile flow. the rise in flow was accompanied by a parallel increase in the biliary clearance of erythritol and the rate of biliary excretion of inorganic ions, whereas the bile acid excretion remained constant. ...1979223377
feline plasma cortisol (hydrocortisone) measured by radioimmunoassay.plasma cortisol (hydrocortisone) was measured by radioimmunoassay in 6 normal cats. blood was collected from the cats by venipuncture at intervals of 3 hours for 3 days. resting plasma cortisol concentrations averaged 17.0 +/- 2.8 (sd) ng/ml and ranged from nondetectable (less than 3 ng/ml) to 82.8 ng/ml. of 144 plasma samples, 95% contained less than 40 ng of cortisol/ml. circadian rhythm of cortisol secretion was not detected, suggesting that adrenal function tests may be started in feline pat ...1979223475
effect of vanadate on cardiac contraction and adenylate cyclase. 1979223558
[presence of enzymes catalyzing udp-glucose biosynthesis in a low density golgi fractions of cat hepatocytes].a golgi-rich fraction is prepared from cat hepatocytes by the means of a four-step sucrose density gradient. the material applied to this gradient is composed either of smooth microsomes prepared from healthy animals, or of total microsomes prepared from cat treated by 50 per cent ethanol (0.6 g/100 g body weight, administered by stomach tube). a light fraction (d : 1.10) is obtained by the two procedures. it does not show any glucose-6-phosphatase activity, but is enriched in sialyltransferase, ...1978223665
[effect of leucine-enkephalin on the interneuronal transmission of excitation].in the experiments on non-anesthetized flaxedil-immobilized cats it has been shown that the injection of leucin-enkephalin (1 mg) into the lateral ventricle of the brain is followed by the inhibition of evoked potentials in the ventrolateral columns of the spinal cord and of segmental interneuronal transmission in the spinal cord as well as by the reduction of the amplitude of potentials in the s i zone of the brain cortex induced by the sciatic nerve stimulation. naloxone (1 mg/kg, i.v.) preven ...1979223685
the ascending tract of deiters' conveys a head velocity signal to medial rectus motoneurons. 1979223719
changes in the visual system of monocularly sutured or enucleated cats demonstrable with cytochrome oxidase histochemistry.endogenous cytochrome oxidase activity within the mitochondria of neurons and neuropil was demonstrated histochemically under normal and experimental conditions. since enzymatic changes were noted with chronic neuronal inactivity in the auditory system (wong-riley et al), the present study sought to examine functionally induced enzymatic changes in the visual system of kittens. eight kittens were used experimentally: 5 had monocular lid suture for varying periods of time; one had binocular lid s ...1979223730
isotherm of alcohol-cooled cryoprobe.the spread of cooling from the tip of a cryoprobe placed in the ventral posterior lateral nucleus of the thalamus in 10 cats was determined. a 20 degrees c isotherm was described as having a diameter of 4 mm and extending 2 mm below the tip of the cryoprobe and tapering up along the shaft of the cryoprobe for a distance of 2 mm, when the cryoprobe tip temperature was maintained at 3 degrees c.1979223738
feedback loop between locus coeruleus and spinal trigeminal nucleus neurons responding to tooth pulp stimulation in the rat.studies were performed to elucidate reciprocal relationships between locus coeruleus (lc) and spinal trigeminal nucleus (stn) neurons responding to tooth pulp (tp) stimulation using rats anesthetized with alpha-chloralose. lc conditioning stimulation inhibited stn field potential as well as orthodromic spike generation of stn neurons produced by ipsilateral tp stimulation, confirming the previous findings in cats that lc neurons played an inhibitory role in the orthodromic transmission in stn ne ...1979223743
effect of veratrum alkaloids on right and left atrial receptors in the cat.1. the effects of veriloid and veratridine on right and left atrial receptors have been studied in cats. 2. threshold doses of these drugs for right atrial receptors were found to be almost twice those for left atrial receptors. beyond threshold doses, however, the dose-response curves were similar. 3. the sensitivity of left atrial receptors to veratridine was not altered by an increase in pco2 and/or decrease in po2 of left atrial blood. therefore, the difference in the behaviour of left and r ...1979223786
epileptogenic doses of penicillin do not reduce a monosynaptic gaba-mediated postsynaptic inhibition in the intact anesthetized cat. 1979223865
[mechanisms of changes in hemodynamics after reducing the volume of circulating blood]. 1979223890
phosphomonoesterases in the male genital system of some mammals.the various male genital organs of the experimental animals used in this investigation (rat, guinea pig, rabbit, cat and dog) showed a widely different localizations of alkaline and acid phosphatases. alkaline phosphatase was presented as secretory, stromal, nuclear and vascular, while with acid phosphatase, distinction was made only between secretory and nuclear phosphatases. although the morphological distributions of both enzymes were sometimes overlapping, they were not identical.1978223941
morphological and cytochemical study of a hypothalamochiasmatic perivascular neuronal system.the topographical localization and some cytochemical characteristics of groups of perivascular neurons in the hypothalamus and in the optic chiasma have been studied. in the anterior hypothalamic area there are neuronal groups located around the blood vessels which penetrate the optic chiasma still associated with neurons. these perivascular neurons show some characteristics similar to those observed in neurosecretory hypothalamic neurons, but differ from them in that they show a greater intensi ...1979224026
a simple method for quantitating salivary levels of virus using calcium alginate swabs. 1979224079
cytologic observations on axotomized feline betz cells. ii. quantitative ultrastructural findings.quantitative electron microscopic examination was made of betz cells of two unoperated cats as well as cats subjected to left lateral funiculotomy 5, 10, 28 and 49 days before sacrifice. the percent cytoplasmic composition of chromatolyzed, right-sided betz cells contributed by cisternal elements of rer, golgi apparatus and dense bodies and the percent perikaryal membrane apposed by subsurface cisterns were unchanged from the normal despite marked qualitative alterations of the cytoplasm. howeve ...1979224151
the actions of excitatory amino acids on motoneurones in the feline spinal cord.1. combined recording or ionophoretic electrodes of the concentric type were used to investigate the depolarizing responses of dl-homocysteate (dlh) and l-glutamate in cat lumbar motoneurones. 2. typically, dlh responses were slow both in onset and recovery, while glutamate responses were fast in onset and recovery and were frequently accompanied by a post-response hyperpolarization. 3. dlh responses (smaller than those necessary to evoke firing) were accompanied by a stable decrease in gm. this ...1979224166
pathogenesis of experimental feline leukemia virus infection. 1979224237
upper respiratory disease in cats. 1979224303
[polysynaptic effects in neurons of the cervical portion of the cat spinal cord induced by activation of long propriospinal pathways].effects evoked in cervical moto- and interneurons by stimulation of lateral (lf) and ventral (vf) funicles at low thoracic level were studied in anaesthetized cats; degeneration of descending supraspinal fibres was provided by preliminary cord sections. lf and (or) vf stimulation evoked psps (usually mixed) in 57 of 90 studied motoneurons. monosynaptic epsps were "primary" actions in 9 motoneurons while poly(di)-synaptic epsps or ipsps--in the rest. intensity of excitatory synaptic action on mot ...1979224327
formation of tonic and phasic type reactions in segmental interneurons. 1978224335
role of adrenergic structures in functional control over the cerebral circulation.an investigation of the cerebral circulation by the thermoelectric method showed that stimulation of the cervical sympathetic nerve leads to considerable changes in the blood supply to the brain. the changes in blood flow are biphasic in character: an initial small increase is followed by a decrease below the original level. pharmacological analysis with alpha and beta adreno-blockers showed that the constrictor response of the cerebral vessels is due to excitation of alpha-adrenergic structures ...1978224339
studies on the release of renin by direct and reflex activation of renal sympathetic nerves. 1979224403
comparison of radiopaque perfluorocarbon and ethiodol in lymphography.lymphangiography was performed on 40 adult cats, 39 dogs, 20 rabbits, and 12 rats of mixed sex using ethiodol or radiopaque perfluorocarbon (bpc). ethiodol was more radiodense than rpc, but imaging of lymph channels and nodes was satisfactory with the latter. rpc could be infused rapidly, while ethiodol infusion was time consuming. rpc was biologically inert; ethiodol produced both local and systemic inflammatory reactions. the lymph node distribution with rpc was more uniform and persisted for ...1979224417
involvement of different exogenous feline leukemia virus subgroups in the generation of independent feline sarcoma virus isolates. 1979224571
[effect of emotional stress on sleep dynamics in cats].emotional stress was developed in cats by putting them in one cage with dogs for 24 hours. then the 24 hours sleep-walking cycles records revealed prolonged rem stage in day time or at night in five animals out of seven, and in six animals a general increase of rem sleep duration over 24 hours. simultaneously, in six animals the length of drowsiness and of deep slow-wave sleep stages was reduced. increased overall sleep duration in the 24 hours was recorded in five cats. sleep changes dynamics a ...1979224615
surgical management of insulinoma.three patients with insulinoma have been presented. accurate diagnosis, localization and multiplicity are possible employing angiography, sonography, cat and insulin concentration determinations of specimens obtained by percutaneous, transhepatic simultaneous sampling of the portal, splenic and superior mesenteric veins. meticulous exploration of the gland will permit enucleation rather than major resection to be a feasible solution and the operation of choice.1979224695
ascending spinal pathways for the somatosympathetic a and c reflexes.sympathetic unit nerve activity was recorded from the cervical sympathetic trunk of anesthetized, vagotomized, and carotid sinus-denervated cats. single pulses or short trains of pulses with suprathreshold intensity for afferent c fibers were applied to the common peroneal nerve to elicit somatosympathetic a or simultaneous a and c reflexes, respectively. bilateral lesions of an ascending spinal pathway in the dorsolateral sulcus area (dls) of the t12 spinal cord eliminated the sympathetic c ref ...1979224716
occurrence of anaerobic bacteria in diseases of the dog and cat.a survey for anaerobic bacteria was conducted in 314 clinical specimens from dogs and cats. a total of 187 anaerobic isolates in pure and mixed culture were isolated from 111 of the specimens that contained anaerobic bacteria. common isolated included actinomyces (9.1%), clostridium perfringens (19.3%), other clostridium spp (11.2%), peptostreptococcus anaerobius (7.5%), bacteroides melaninogenicus (13.4%), other bacteroides spp (17.6%), and fusobacterium necrophorum (5.3%). anaerobic bacteria w ...1979224739
the phenomenon of polykaryocytosis induced by blv in mixed cultures: specificity, mechanisms and application to the diagnosis of blv infection in cattle. 1978224768
comparison of virus-positive and virus-negative cases of feline leukemia and lymphoma.one hundred eighty-four cases of feline leukemia and lymphoma diagnosed in boston from 1972 through 1976 were investigated. fifty-eight % of these cases were lymphoma, and 42% were leukemia. sixty-seven % of the cats had positive fluorescent antibody tests for circulating feline leukemia virus. the rest (33%) were virus negative. clinically and epidemiologically, the virus-positive and virus-negative cases were remarkably similar except for their age at diagnosis. virus-negative cats tended to b ...1979225010
influence of adrenal corticosteroids on the susceptibility of cats to feline leukemia virus infection.the natural resistance of adult specific-pathogen-free cats to feline leukemia virus (felv) was abrogated by treatment with various doses of a synthetic corticosteroid, methylprednisolone acetate (mpa), prior to either oral-nasal or i.p. inoculation of felv. persistent viremia was induced in 82% (18 of 22) of mpa-treated cats versus 11% (1 of 9) of age-matched control cats. mpa-treated felv-inoculated cats developed prolonged lymphopenia (2 to 8 weeks postinoculation) and a delayed antibody resp ...1979225025
action of angiotensin i converting enzyme inhibitor on the control of renal function in the cat. 1979225092
effects of vasopressin and cyclic amp on water transport at arachnoid villi of cats.the effects of vasopressin and cyclic amp on water transport at arachnoid villi into the superior sagittal sinus were examined using the isolated meninges preparations of cats. the meninges preparation, the superior sagittal sinus of which was opened at the midline of the outer surface, was held between two polyethylene tubes. the tubes were fixed vertically in the way that the opened surface of the sinus was directed downward and arachnoid surface upward. water transport was determined by measu ...1979225164
effect of chronic ethanol treatment on specific [3h]ouabain binding to (na+ + k+)-atpase in different areas of cat brain.chronic ethanol administration to cats increased specific [3h]ouabain binding by 63% in cerebral cortex, 47% in cerebellum, 84% in amygdala, and 100% in hippocampus when the binding assays were performed in the presence of 160 nm [3h]ouabain. there was no significant change in specific [3h]ouabain binding in hypothalamus, thalamus, corpus striatum, and brain stem following chronic ethanol ingestion. scatchard analysis revealed that enhancement of specific [3h]ouabain binding following chronic et ...1979225178
synaptic organization of the medial acessory olivary nucleus of the cat.light microscopically the morphological characteristic of neurons and ultrastructurally the synaptic organization of medial accessory olivary nucleus of cat was studied. different types of chemically mediated as well as electric synapses were observed. the terminal boutons contain mainly clear synaptic vesicles, but small and large dense core vesicles are also available. in the neuropil of the nucleus characteristic glomeruli with central dendritic core were establish. the dendritic profiles wer ...1979225382
postsynatpic population potentials recorded from ventral roots perfused with isotonic sucrose: connections of groups ia and ii spindle afferent fibers with large populations of motoneurons. 1979225448
disuse enhances synaptic efficacy in spinal mononeurones.1. monosynaptic excitatory post-synaptic potentials (e.p.s.p.s) were recorded from triceps surae motoneurones in the cat following section or chronic conduction block of the medial gastrocnemius (m.g.) nerve with tetrodotoxin (ttx) or after daily stimulation of the sciatic nerve. 2. the mean maximum amplitudes of homonymous and heteronymous monosynaptic e.p.s.p.s evoked by stimulation of the mg. nerve were reduced significantly between 1 and 2 weeks after section of the muscle nerve. the mean am ...1979225473
nature and distribution of feline sarcoma virus nucleotide sequences.the genomes of three independent isolates of feline sarcoma virus (fesv) were compared by molecular hybridization techniques. using complementary dnas prepared from two strains, sm- and st-fesv, common complementary dna's were selected by sequential hybridization to fesv and feline leukemia virus rnas. these dnas were shown to be highly related among the three independent sarcoma virus isolates. fesv-specific complementary dnas were prepared by selection for hybridization by the homologous fesv ...1979225544
nature of the transport adenosine triphosphatase-digitalis complex: xiv. inotropy and cardiac glycoside interaction with na+,k+-atpase of isolated cat papillary muscles. 1979225652
[ovarian tumors in animals with special reference to dogs]. 1979225715
studies on the synaptic interconnection between bulbar respiratory neurones of cats.in cats anaesthetized with pentobarbital, medullary respiratory neurones of both dorsal and ventral populations were recorded intracellularly with 1 mol.l-1 kcl-electrodes. the neurones were classified according to the projection of their axons to the spinal cord (bulbospinal neurones) or to the vagal nerves (vagal neurones). those neurones which could not be activated antidromically (naa-neurones) by either procedure were subdivided into (inspiratory) r beta-neurones, which were monosynapticall ...1979225726
[feline leukemia virus (felv) i]. 1979225795
role of peripheral afferent nerve fiber in acupuncture analgesia elicited by needling point zusanli.needling acupuncture point zusanli shows a significant suppressive effect characterized by the response of jaw movement. the afferent analgesic impulses arising from the point zusanli for producing this effect are transmitted largely by a beta gamma fibers in the peroneal nerve. sufficient amount of a beta gamma fibers brought in to action is an important factor in achieving this prominent analgesic effect. the inhibitory action of the large fibers, such as a beta gamma, mediating analgesic impu ...1979225797
interaction of peripheral and cerebellar inputs to red nucleus neurons.in chloralose anesthetized cats responses of red nucleus neurons to cerebellar cortical or peripheral stimulation are described. interactions between cerebellar (conditioning) and peripheral (test) stimulations were studied at various interstimulus intervals. peripheral stimulation alone typically evoked a complex response consisting of an early (15 ms latency) burst, a period of depression of activity (inhibition, lasting up to 300 ms) and a late, long-lasting (on an average 300 ms) excitation. ...1979225933
reversibility of changes in evoked spinal response following graded spinal cord compression.the spinal evoked response obtained in cats at a site immediately rostral to the site of a graded spinal cord compression is described. they usually show an earlier decrease in amplitude than cortical sep's and the appearance of a particular positive potential. the degree of reversibility after decompression is variable and is not correlated with histological damage.1979225938
effects of streptomycin on the cortical neurons in the cat.data concerning the effects of streptomycin application on the brain cortex are very scarce and nonconcordant, despite routine intra-thecal administration of this drug. experiments peformed in 15 adult cats permitted us to observed that application of streptomycin sulphate on the brain cortex leads to a real cortical depression, demonstrated by the disappearance of spontaneous spikes, lack of cortical fast activity and lack of hippocampal theta activity. the direct cortical response disappears t ...1979226019
virus isolation and serum antibody responses after infection of cats with transmissible gastroenteritis virus. brief report.transmissible gastroenteritis virus was administered orally to cats. no clinical disease resulted but infectious virus was isolated from faeces for up to 22 days after infection and serum antibody was detected by neutralisation and immunofluorescence tests.1979226036
combined dynamics of eeg and evoked potentials. i. studies of simultaneously recorded eeg-epograms in the auditory pathway, reticular formation, and hippocampus of the cat brain during the waking stage.this study is carried out on single (not averaged) recordings combining the spontaneous activity preceding the stimulus onset and the ep recorded upon acoustical stimulation. these recordings, which we call eeg-epograms, are measured simultaneously from different subdural brain structures, such as the auditory cortex, medial geniculate nucleus, inferior colliculus, reticular formation and the hippocampus of awake cats. using a combined analysis procedure (c.a.p.), the relevant frequency componen ...1979226179
static and dynamic fusimotor interaction and the possibility of multiple pace-makers operating in the cat muscle spindle.the interaction of static and dynamic fusimotor activation on the firing of primary muscle spindle afferents has been studied in the cat soleus muscle at constant length and during sinusoidal stretching. cycle histogram analysis revealed summation of static and dynamic action during the peak of the afferent response to sinusoidal stretching, while static action completely occluded the dynamic effect during the trough of the response. occlusion was complete as long as, for single fusimotor activa ...1979226208
pharmacological characterization of gaba receptors mediating vasodilation of verebral arteries in vitro.gaba (gamma-aminobutyric acid) produced a dose-dependent dilation of isolated cat and dog cerebral artery segments which had been given an active, tonic contraction by either prostaglandin f2 alpha or serotonin. no effect of gaba on extracranial blood vessels was observed. the gaba-induced dilation could be blocked in a dose-dependent manner by either bicuculline or picrotoxin. the latter agent appeared to act as a competitive antagonist. gaba agonists muscimol, imidazoleacetic acid, delta-amino ...1979226209
enhancement during rem sleep of extracellular potassium ion activity in the reticular formation. 1979226216
optimal motor patterns for activating mammalian muscle. 1979226227
locus coeruleus and substantia nigra: involvement in morphine-induced behavior.cats pretreated with morphine (5 mg/kg, ip) received naloxone into the area of the locus coeruleus (lc) or the area of the substantia nigra (sn). the lc-treated animals stopped the morphine-induced stereotyped behavior and showed normal but hyperactive behavior. the sn-treated animals, however, ceased their movements of the head and the forelegs, adopted a rigid posture with extended forelegs and became hypoactive. it is concluded that both the lc area, which contains noradrenergic cell bodies, ...1979226230
changes in cortical sensory responses with a cryogenic blockade of nucleus ventralis posterolateralis. 1979226234
the effects of cold-induced muscle spindle secondary activity on monosynaptic and stretch reflexes in the decerebrate cat.the effects of muscle spindle secondary ending activity on the stretch reflex were studied in unanesthetized decerebrate cats. activation of secondary endings was accomplished by reducing the muscle temperature. this has been shown to cause a sustained asynchronous discharge from secondary endings. cooling of the medial gastrocnemius or lateral gastrocnemius-soleus muscles caused an increase in the phasic and tonic components of their stretch reflexes. cooling of the relaxed medial gastrocnemius ...1979226253
neck muscle and trigeminal input to the upper cervical cord and lower medulla of the cat.experiments on chloralose-anaesthetized cats have shown that low-threshold neck muscle afferents project to laminae iv and v in the dorsal horn of the upper cervical cord, to lamina vi including the region which encompasses the central cervical nucleus, as well as to extensive regions of the ventral horn. at posterior medullary levels projections also exist to laminae iv, v, and vi of the spinal nucleus of v (although those to lamina iv are circumscribed), to the deep layers and lateral margin o ...1979226254
augmentation of cyclic amp content induced by lysophosphatidyl choline in rabbit hearts. 1979226263
effects of prazosin and phentolamine on cardiac presynaptic alpha-adrenoceptors in the cat, dog and rat.in cats, dogs and rats, clonidine (20.0 microgram/kg, i.v.) reduced the sustained tachycardia evoked by a continuous electrical stimulation of cardiac sympathetic nerve fibres. this effect of clonidine resulting from stimulation of cardiac presynaptic alpha-adrenoceptors could be completely antagonized by phentolamine and prazosin in the dog and the cat, whereas in the rat, prazosin, unlike phentolamine, failed to effectively inhibit the clonidine induced reduction in heart rate. the calculated ...1978226338
[effects of morphine on the activity of various dorsal horn neurons of the spinal cord involved in nociception].in spinal preparation, morphine exerts a specific direct inhibitory action on the activities of dorsal horn neurones induced by noxious stimuli. the effect of morphine is preferential for the responses evoked by a delta and c fibre afferents and its specificity of action has been demonstrated pharmacologically in terms of isomerism, dose dependency and reversal of the inhibitions by opiate antagonists. these results are in good agreement with recent data related to the localization at the spinal ...1979226344
pharmacological activities of acetal derivatives of hemicholinium no. 3.acetal derivatives of hemicholinium no. 3 (hc-3) were synthesized and their chemical structures were confirmed by spectrophotometric evidence and elemental analysis. the acetals elicited a biphasic pattern of neuromuscular inhibition in the cat: (a) an immediate inhibition (early phase block) was judged to be curare-like as responses to acetylcholine (close i.a.) were abolished by acetal administration and reversal of inhibition was effected by neostigmine (25 micrograms/kg); (b) a slow, progres ...1979226372
non-linear spatial summation in cat retinal ganglion cells at different background levels. 1979226387
[tercuronium, a new nondepolarizing myorelaxant with high activity and selective action].tercuronium is p',p"-bis-triethylammonium-p-terphenyl dibenzosulfonate. as a curarelike agent tercuronium is 4--8 times as potent as (+)-tubocurarine. the time of the development and lasting of the blocking effect of tercuronium is approximately the same as that of (+)-tubocurarine. in a blocking dose tercuronium does not exert any effect either on the vegetative ganglia or arterial blood pressure. partial blocking of the transmission through the vegetative ganglia as well as an insignificant an ...1979226400
[multidisciplinary approach to studying inhibition in the cerebral cortex]. 1979226418
[nature of the hyperpotassic composition of the medium surrounding individual tissue mechanoreceptors].the ouabain effect on potassium concentration in the pacini corpuscle fluid was studied using continuous perfusion of cat's mesenteric receptors with ouabain in ringer's bicarbonate solution. to check the solution penetration into the corpuscles, na36cl and (g-3h)-ouabain were used. 2 . 10(-2) mm ouabain reduced (k+) in corpuscle fluid. the high potassium concentration in pacini corpuscle fluid seems to be due to na+--k+-atpase system.1979226420
[adrenergic mechanisms of changes in the resistance and volume vessels of the small intestine in the presence of a reduced volume of circulating blood].in humorally isolated small intestine, the 10--20%--decrease in the perfusing blood volume against the background of augmented vascular resistance of the small intestine, induces different shifts of the latter's vascular capacitance. at the blockade of small intestine's beta--adrenoreceptors the decrease does not practically tell on the character of shifts in the intestine's resistance and capacitance while the blockade of alpha--adrenoreceptors abolishes the augmentation of these parameters.1979226421
[comparative effects of nialamide, imipramine and sulpiride on paradoxical sleep in the electrode-implanted, unrestrained cat]. 1978226435
effect of glucagon, secretin, and vasoactive intestinal polypeptide on the feline lower esophageal sphincter: mechanisms of action. 1979226449
relationship of geniculate and occipital pgo waves and the effects of nonvisual sensory activity.the nature of occipital pgo waves (rem) was addressed by comparing the occipital pgo waves measured at the marginal gyrus with the geniculate pgo waves and the occipital pgo waves "directly" transmitted to the occipital cortex. the directly transmitted pgo waves lack the first short positive-going spike that precedes the negative phase of the occipital pgo waves. the "directly" transmitted pgo wave was recorded from cats with either deafferented or excised lg nucleus. the "directly" transmitted ...1979226493
correlated effects of acetylcholine and cyclic guanosine monophosphate on membrane properties of mammalian neocortical neurons.the effects of successive extracellular iontophoresis of acetylcholine (ach) and atropine, and intracellular hyperpolarizing iontophoresis of cyclic gmp (cgmp) were studied in single neurons of the coronal-pericruciate cortex of awake cats. (a) fifty-seven percent of the neurons that were tested responded to ach with an increase in neuronal input resistance (rm) and 50% responded to ach with an increase in firing rate; 65% responded to cgmp with an increase in rm and 60% responded to cgmp with a ...1979226660
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