| congenital hypothyroidism screening program in turkey: a local evaluation. | it was aimed to evaluate the national congenital hypothyroidism program in terms of thyroid-stimulating hormone (tsh) cut-off level, frequency of cases that required treatment and the stages before treatment in the kocaeli district area. this research was performed with the contribution of kocaeli university medical faculty, pediatric endocrinology department, and the kocaeli local health district. 25,188 babies born in 2009 were evaluated. the previous laboratory data including heel prick sampl ... | 2012 | 23692784 |
| [frequency of subclinical thyroid problems among women during the first trimester of pregnancy]. | thyroid hormones play an important role in fetal neural and cognitive development. therefore thyroid abnormalities should be detected and treated early during pregnancy. | 2012 | 23677185 |
| evaluation of the seventh edition of the american joint committee on cancer tumour-node-metastasis (tnm) staging system for patients undergoing curative resection of hepatocellular carcinoma: implications for the development of a refined staging system. | this study aimed to evaluate the seventh edition of the american joint committee on cancer (ajcc) tumour-node-metastasis (tnm) staging system and to compare its efficacy with those of the fifth and sixth editions of the ajcc staging system and the tnm staging system defined by the liver cancer study group of japan. | 2012 | 23659567 |
| early adiposity rebound and obesity in children with congenital hypothyroidism. | earlier adiposity rebound (ar) is correlated with obesity. our goal is to examine rates of obesity and ar in congenital hypothyroidism (cht) and analyze the risk factors of obesity. | 2012 | 23590955 |
| dyslipidemia in subclinical hypothyroidism and the effect of thyroxine on lipid profile. | subclinical hypothyroidism (sh) has a prevalence between 4% and 10.5% in various studies. the burden of sh in india is expected to increase with increasing iodine sufficiency. studies have shown conflicting results concerning not only the degree of lipid changes in sh but also the effect of thyroxine substitution therapy. indian studies on dyslipidemia in sh and the effect of thyroxine on lipid profile are currently lacking. | 2012 | 23565423 |
| a case of simultaneous occurrence of graves' disease and hashimoto's thyroiditis. | simultaneous occurrence of hashimoto's thyroiditis (ht), and graves' disease (gd) is rare. | 2012 | 23565420 |
| cretinism revisited. | cretinism is a condition of severely stunted physical and mental growth due to untreated congenital hypothyroidism. it has been largely eliminated in the developed world, though we still continue to see cases in india. | 2012 | 23565419 |
| empty sella syndrome - beyond being an incidental finding. | empty sella is characterized by the herniation of the subarachnoid space within the sella, which is often associated with some degree of flattening of the pituitary gland. this study was undertaken to evaluate the clinical and hormonal profile in patients with empty sella. | 2012 | 23565413 |
| plurihormone secreting pituitary macroadenoma masquerading as thyrotoxicosis: clinical presentation and diagnostic challenges. | thyroid stimulating hormone (tsh) secreting adenomas are the rarest type of pituitary adenomas (1:1000000 in the population; 0.2- 2.8% of adenomas). plurihormonal thyrotropic adenomas are even rarer usually having cosecretion of growth hormone (gh) and prolactin. we report perhaps for the first time, tsh, gh, adrenocorticotrophic hormone (acth) and gonadotropins secreting pituitary macroadenoma diagnosed in a 40 year lady presenting with features of thyrotoxicosis for 5 months, amenorrhea for 3 ... | 2012 | 23565411 |
| thyroid disorders in pregnancy. | thyroid disorders are common in pregnancy and the most common disorder is subclinical hypothyroidism. due to the complex hormonal changes during pregnancy, it is important to remember that thyroxine requirements are higher in pregnancy. according to recent american thyroid association (ata) guidelines, the recommended reference ranges for tsh are 0.1 to 2.5 miu/l in the first trimester, 0.2 to 3.0 miu/l in the second trimester, and 0.3 to 3.0 miu/l in the third trimester. maternal hypothyroidism ... | 2012 | 23565370 |
| hemolysis in extracorporeal circulation: relationship between time and procedures. | extracorporeal circulation (ec) is very important in cardiac surgery but causes significant damage to the blood, including hemolysis. | 2012 | 23515726 |
| laparoscopic excision of local recurrence of renal cell carcinoma. | to report a single center's experience with laparoscopic excision of local recurrence of renal cell carcinoma. | 2012 | 23484571 |
| [effects of electro-acupuncture combined general anesthesia on myocardial injury of high blood sugar patients with coronary heart disease in the perioperative phase]. | to investigate the effects of electro-acupuncture (ea) combined general anesthesia on myocardial injury of high blood sugar patients with coronary heart disease (chd) in the perioperative phase. | 2012 | 23469596 |
| colorimetric assay for t4 polynucleotide kinase activity based on the horseradish peroxidase-mimicking dnazyme combined with λ exonuclease cleavage. | t4 polynucleotide kinase (pnk) plays a critical role in various cellular events. here, we describe a novel colorimetric strategy for estimating the activity of pnk and screening its inhibitors taking advantage of the efficient cleavage of λ exonuclease and the horseradish peroxidase-mimicking dnazyme (hrpzyme) signal amplification. a label-free hairpin dna with the sequence of hrpzyme was utilized in the assay. the 5'-hydroxyl terminal of the hairpin dna was firstly phosphorylated in the presenc ... | 2012 | 23427805 |
| traditional chinese medicine etiology and pathogenesis of acquired immune deficiency syndrome in simian immunodeficiency virus-infected chinese rhesus macaques. | to investigate the traditional chinese medicine (tcm) etiology and pathogenesis of acquired immune deficiency syndrome (aids) by 18-month observation of chinese rhesus macaques infected with simian immunodeficiency virus (siv) mac239. | 2012 | 23427397 |
| higher dose of methimazole causes frequent adverse effects in the management of graves' disease in children and adolescents. | methimazole (mmi) is used as a first-line antithyroid drug in children and adolescents with graves' disease (gd). the aim of this study was to evaluate the correlation between the initial dose of mmi and the clinical course of gd after treatment. | 2012 | 23426814 |
| tsh suppression after intravenous glucocorticosteroid administration in preterm infants. | reports have described that, in adults, steroids suppress thyroid-stimulating hormone (tsh) and triiodothyronine (t3) and might suppress thyroxine (t4). no data have been reported for thyroid hormone changes before or after administration of glucocorticoid in preterm infants. | 2012 | 23426812 |
| in congenital hypothyroidism, an initial l-thyroxine dose of 10-12 μg/kg/day is sufficient and sometimes excessive based on thyroid tests 1 month later. | current guidelines recommend an initial l-thyroxine (l-t4) dose of 10-15 μg/kg/day for the treatment of congenital hypothyroidism (ch). we analyzed our data for the treatment outcome at 1 month after we noted a frequent overtreatment even at the lower end of this dose range. | 2012 | 23426811 |
| surgical treatment of lumbar vertebral collapse in a patient with parkinson's disease: a case report. | parkinson's disease (pd) frequently develops postural abnormalities including extreme neck flexion and trunk flexion. patients with pd sometimes have osteopenia and vertebral deformity due to the destruction of fragile bone can be also associated with the spinal deformity. surgical treatment for these patients is very difficult. we encountered a patient with pd presenting severe trunk sagittal and frontal deformity. the patient had cauda equina syndrome due to progressive vertebral collapse of t ... | 2012 | 23412270 |
| effects of treatment with l-thyroxin on glucose regulation in patients with subclinical hypothyroidism. | we examined effects of treatment with 1-thyroxin on glucose regulation in patients with subclinical hypothyroidism. | 2012 | 23409511 |
| the role of selenium in cadmium toxicity: interactions with essential and toxic elements. | 1. the study was part of a project designed to investigate if organic selenium (se) can ameliorate the toxic effects of cadmium (cd). the main objective of the present study was to investigate, in the chicken, the interactions between se, cd and the following elements: sb, ca, cr, co, cu, fe, pb, mg, mn, mo, ni, v and zn. 2. a total of 300 1-d-old chickens (broilers) were randomly distributed among 4 dietary treatments with 5 replicate pens per treatment. in t1, chickens were fed on a diet with ... | 2012 | 23398427 |
| epidemiology and clinical characteristics of larynx and hypopharynx carcinoma: a comparative study in the hainaut and review of the literature. | the epidemiology and clinical picture of laryngeal and hypopharyngeal carcinomas have changed significantly in the past 50 years. the aim of this study was to analyze selected epidemiological and clinical characteristics of laryngeal and hypopharyngeal carcinoma. | 2012 | 23397823 |
| new modalities to treat laryngeal cancer. | early laryngeal cancer comprises t1 and t2 stages of the disease. open functional operations achieve local control of the disease in 90-95% of t1 patients and in 70-90% of t2 patients. primary rt achieves local control in 85-94% of t1 tumors and in 70-80% of patients with t2 tumors. introduction of endoscopic laser surgery resulted in further popularization of preservation laryngeal surgery, whereby equally successful treatment results are achieved with minimal invasiveness. quality of voice is ... | 2012 | 23397746 |
| [t∧g: an elementary integrated prognostic system for renal carcinoma n0 m0]. | introduction: 25-30% of patients with renal cell carcinoma (rcc) develop metastatic progression during follow up. for this reason many prognostic systems have been developed to try to predict the possibility of recurrence. unfortunately these systems are often complex in daily use.
patient and methods: 1089 were selected from a total of 1985 patients undergoing surgery for renal cell cancer. we have excluded patients with a benign diagnosis, lymph node or distant metastases at diagnosis, with no ... | 2012 | 23371278 |
| the effect of protease and xylanase enzymes on growth performance and nutrient digestibility in finisher pigs. | two 2 × 2 factorial experiments were conducted to investigate the interaction between xylanase (0 vs. 200 mg/kg) and protease (0 vs. 200 mg/kg) enzyme supplementation on growth performance (exp. 1) and coefficient of ileal and total tract apparent digestibility in grower-finisher pigs (exp. 2). one hundred and twenty-eight individual fed pigs (bw = 34.2 kg; n = 32) were assigned to 1 of 4 dietary treatments: basal diet (t1), t1 + xylanase enzyme (t2), t1 + protease enzyme (t3), or t1 + xylanase ... | 2012 | 23365384 |
| the long-term regulation of food intake and body weight depends on the availability of thyroid hormones in the brain. | we evaluated the contribution of the thyroid hormones to the long-term maintenance of feeding behavior and body weight, while distinguishing their direct central effects from those resulting from the metabolic rate in the peripheral tissues. | 2012 | 23391881 |
| association between bipolar affective disorder and thyroid dysfunction. | bipolar affective disorder may be associated with alterations in thyroid function. a comprehensive thyroid assessment is important for assessing clinical and sub-clinical imbalances linked to a variety of mood disorders like bipolar affective disorder. | 2012 | 23380316 |
| assessment of left ventricular diastolic dysfunction in sub-clinical hypothyroidism. | adverse cardiovascular effect of hypothyroidism has been identified in many studies. early identification of patients with sub-clinical hypothyroidism may lead to early treatment and thereby favourable effect on cardiovascular morbidity and mortality. | 2012 | 23378686 |
| the effect of vitamin a supplementation on thyroid function in premenopausal women. | vitamin a and its retinoid derivates play an important role in regulation of normal growth and development. vitamin a has been shown to regulate thyroid hormone metabolism and inhibit thyroid-stimulating hormone (tsh) secretion via down regulation of tsh-β gene expression; however, the effect of vitamin a on thyroid function in obese individuals who are at higher risk of subclinical hypothyroidism is still unclear. in the present study we investigate the impact of vitamin a supplementation on th ... | 2012 | 23378454 |
| [study on mechanism of traditional chinese medicines reducing phlegm and resolving masses in treatment of goiter]. | to discuss the mechanism of traditional chinese medicines reducing phlegm and resolving masses in treatment of iodine deficiency-induced goiter by observing the expression of growth factors and the balance-regulating mechanism of proliferation and apoptosis. | 2012 | 23373220 |
| advantages of voice reproduction and the development of a biomimetic self-regulating double-clack valve for a prosthesis of the larynx--a feasibility study. | the human larynx is a versatile organ. main functions are phonation, protection and regulation of the air ways. patients suffer severely from the diagnosis of a laryngeal carcinoma of the stages t3 and t4. in most cases this diagnosis will lead to a total laryngectomy, which is usually dissatisfying in the sense of postoperative rehabilitation. the postoperative consequences include the loss of the native voice, the loss of regular air ways via mouth and nose, sense of smell, and the inability t ... | 2012 | 23366020 |
| [a case of acute exacerbation of interstitial pneumonia after appendectomy managed with spinal anesthesia]. | an 88-year-old woman was admitted with acute appendicitis. she had been treated with prednisolone and home oxygen therapy for interstitial pneumonia. her respiratory state on admission was grade 2 of hugh-jones' classification, and plasma kl-6 and sp-d levels were high. seven days after the admission, appendectomy was performed under spinal anesthesia. spinal anesthesia was initiated by injecting 0.5% hyperbaric bupivacaine 2.0ml into l3-4 interspace, and achieved block level was up to t4. durin ... | 2012 | 23362773 |
| [hypothyroidism incidence after multimodal treatment for laryngeal cancer]. | hypothyroidism following total laryngectomy or radiotherapy treatment for laryngeal cancer is not a rare event, especially in advanced stages. there are no reports on the incidence of hypothyroidism in patients who received chemotherapy and radiotherapy. the objective of this study is to determine the incidence of thyroid dysfunction in a group of patients with laryngeal cancer who underwent surgery as sole treatment, total laryngectomy or radiotherapy alone, and patients with combined treatment ... | 2012 | 23351449 |
| [indication of chemoradiotherapy in patients with unresectable t4 breast tumors]. | | 2012 | 23350460 |
| association of inflammation with atrial fibrillation in hyperthyroidism. | the aim of this study was to evaluate the relationship between inflammation and development of atrial fibrillation (af) in patients with hyperthyroidism. | 2012 | 23341838 |
| unusual presentations of a girl with down syndrome: van wyk-grumbach syndrome. | van wyk-grumbach syndrome is a rare disease characterized by precocious puberty associated with prolonged hypothyroidism and multicystic enlarged ovaries. a 9-year-old girl with down syndrome visited our hospital for early menarche. at birth, she showed subclinical hypothyroidism [11.8 μg/dl of thyroxine (t4) and 6.05 μiu/ml of thyroid stimulating hormone (tsh)], but she had not been followed up in our clinic. on physical examination, pubertal tanner stage was breast ii and pubic hair i. laborat ... | 2012 | 23329774 |
| comparison of the anesthetic effects of intrathecal levobupivacaine + fentanyl and bupivacaine + fentanyl during caesarean section. | regional anesthesia techniques are increasingly preferred for caesarean section. the aim of the present study was to compare the anesthetic effects of levobupivacaine + fentanyl and bupivacaine + fentanyl on the mother and newborn during elective caesarean section under spinal anesthesia. | 2012 | 23327030 |
| analysis of reference interval and age-related changes in serum biochemistry and hematology in the specific pathogen free miniature pig. | we analyzed 72 items related to serum biochemistry and hematology in 85 specific pathogen-free (spf) seoul national university (snu) miniature pigs aged 1- to 36-months which originated from a minnesota miniature pig. almost all examined items were similar between male and female pigs. however, some items such as cr level, b/c ratio, c.r.f, ldh, lap and t4 were significantly different between male and female pigs (p<0.05). thirty four examined items showed age-related changes, and the significan ... | 2012 | 23326285 |
| isolation and genotyping of acanthamoeba strains from environmental sources in ahvaz city, khuzestan province, southern iran. | acanthamoeba spp. are free-living amoebae commonly found in the environmental sources such as water, soil, and air. this ubiquitous amoeba is the causative agent of amoebic keratitis (ak). the objective of the present study was to investigate the presence of acanthamoeba spp. in water and soil sources in ahvaz city, khuzestan province, southern iran. | 2012 | 23323088 |
| changes of subtests of wechsler memory scale and cognitive function in subjects with subclinical hypothyroidism following treatment with levothyroxine. | subclinical hypothyroidism has been reported to be associated with disturbed cognitive function. in this study, changes of subtests of the wechsler memory scale and memory quotient were investigated in subjects with subclinical hypothyroidism following treatment with levothyroxine. the aim of the study was a randomized double blind placebo-controlled clinical trial. | 2012 | 23319987 |
| [prevalence of thyroid abnormalities among psoriatic patients]. | psoriasis is a chronic papulosquamous cutaneous disease. the etiology is unknown. several biochemical and immunological processes, which appear in patients with genetic predisposition, lead to enhanced proliferation of epidermal cells, and inflammation of the dermis. thyroid gland hormones cause an increase of epidermal growth factor level, which has an important role in keratinocyte proliferation, which may be involved in psoriasis disease. | 2012 | 23316662 |
| [pharyngocutaneous fistula following total laryngectomy]. | pharyngocutaneous fistula (pcf) is the most common complication after total laryngectomy. | 2012 | 23306575 |
| radioiodine thyroid remnant ablation after recombinant human thyrotropin or thyroid hormone withdrawal in patients with high-risk differentiated thyroid cancer. | to supplement limited relevant literature, we retrospectively compared ablation and disease outcomes in high-risk differentiated thyroid carcinoma (dtc) patients undergoing radioiodine thyroid remnant ablation aided by recombinant human thyrotropin (rhtsh) versus thyroid hormone withdrawal/withholding (thw). our cohort was 45 consecutive antithyroglobulin antibody- (tgab-) negative, t3-t4/n0-n1-nx/m0 adults ablated with high activities at three referral centers. ablation success comprised negati ... | 2012 | 23304637 |
| identifying patients who may be candidates for a clinical trial of salvage accelerated partial breast irradiation after previous whole breast irradiation. | background and objectives. accelerated partial breast irradiation (apbi) has been proposed as an alternative to salvage mastectomy for patients with ipsilateral breast tumor recurrence (ibtr) after prior breast conservation. we studied factors that are associated with a more favorable local recurrence profile that could make certain patients eligible for apbi. methods. between 1980 and 2005, 157 stage 0-ii breast cancer patients had an ibtr treated by mastectomy. clinical and pathological featur ... | 2012 | 23304530 |
| headache as the sole symptom of nasopharyngeal carcinoma and its clinical implications. | this study aimed to investigate the clinical features of npc presenting with headache as the primary or sole symptom. | 2012 | 23304077 |
| [salvage central neck dissection for papillary thyroid cancer]. | to evaluate the salvage central neck dissection (cnd) for papillary thyroid cancer in the patients with suspicious residual positive lymph nodes in the central compartment. | 2012 | 23302163 |
| improved sensitivity for long-distance measurements in biomolecules: five-pulse double electron-electron resonance. | we describe significantly improved long-distance measurements in biomolecules by use of the new multipulse double electron-electron spin resonance (deer) illustrated with the example of a five-pulse deer sequence. in this sequence, an extra pulse at the pump frequency is used compared with standard four-pulse deer. the position of the extra pulse is fixed relative to the three pulses of the detection sequence. this significantly reduces the effect of nuclear spin-diffusion on the electron-spin p ... | 2012 | 23301118 |
| [iodine and thyroid gland with or without nuclear catastrophe]. | iodine, as a trace element, is a necessary and limiting substrate for thyroid gland hormone synthesis. it is an essential element that enables the thyroid gland to produce thyroid hormones thyroxine (t4) and triiodothyronine (t3). synthesis of thyroid hormones and iodine metabolism. three iodine molecules are added to make triiodothyronine, and four for thyroxine - the two key hormones produced by the thyroid gland. iodine deficiency the proper daily amount of iodine is required for optimal thyr ... | 2012 | 23297615 |
| [analysis of mosaic expression of the nptii gene in transgenic tobacco plant lines contrasting in mosaicism]. | differences in the frequency of occurrence of plants with the mosaic phenotype between the nu5 and nu6 lines of transgenic tobacco (nicotiana tabacum) plants remained irrespective of the allelic state of the nptii marker gene. transition of the nptii gene from the hemizygous state (t3) to the homozygous state (t4) was accompanied by an increase in the frequency of mosaics in both lines. transition from the homozygous state (t4) into the hemizygous state (f1) resulted in a further increase in the ... | 2012 | 23297483 |
| congenital hypothyroidism: a review of the risk factors. | this study was aimed to evaluate the situation of congenital hypothyroidism (ch) in guilan using the screening program and determine the correlation of ch with birth weight, gestational age and seasonality. during 2006 to 2010, in guilan province, neonatal screening for ch by measurement of serum tsh level was performed in 3-5 days after birth. all neonates with tsh level ≥ 5mu/l were referred to endocrinologists and serum tsh, t3 and t4 were measured. based on public health data and profiles, t ... | 2012 | 23292624 |
| distribution of contrast medium epidurally injected at thoracic and lumbar vertebral segments. | the epidural distribution of iohexol (0.2 ml/kg) administered at thoracic vertebrae (thoracic group) and lumbar vertebrae (lumbar group) was compared by computed tomographic (ct) epidurography in dogs. the total spread of iohexol was similar between the 2 groups upon reaching a similar cranial level. the maximal ct values were higher at the c7/t1 and t4/t5 levels in thoracic group, but they were higher at the t13/l1 and l4/l5 levels in lumbar group (p<0.05). this result suggests that the distrib ... | 2012 | 23292108 |
| detection of t4 polynucleotide kinase activity with immobilization of tio2 nanotubes and amplification of au nanoparticles. | determination of nucleotide kinase activity is valuable due to its importance in regulating nucleic acid metabolism. herein, we describe a strategy for simply and accurately determining nucleotide kinase activity by tio2 nanotubes mediated signal transition and au nanoparticles amplification. in this method, dna containing 5'-hydroxyl group is self-assembled onto a gold electrode and used as a substrate for t4 polynucleotide kinase (pnk). by the specific immobilization affinity of tio2 nanotubes ... | 2012 | 23291616 |
| [subcarinal lymph node metastasis and strategy of lymphadenectomy in thoracic esophageal carcinoma]. | to assess the metastatic frequency of subcarinal lymph nodes of thoracic esophageal carcinoma and its influencing factors, in order to determine the adequate range of lymph node dissection during esophagectomy. | 2012 | 23291134 |
| association between osteopontin and egfr expression with clinicopathological parameters in hepatocellular carcinoma. | osteopontin (opn) and epidermal growth factor receptor (egfr) are important factors associated with tumor progression, invasion and metastasis in humans. the aim of this study was to assess the correlation of opn and egfr expression with hepatocellular carcinoma (hcc) progression. expression of opn and egfr was assessed by immunohistochemistry in 100 hcc specimens. immunostaining scores (0 to 400) were calculated from the percentage of cells (0 to 100) at each immunostaining intensity and the im ... | 2012 | 23286449 |
| [immunological characteristics in subjects with heart connective tissue dysplasia depending on thyroid hormone levels and vegetative dysfunction]. | patients with heart connective tissue dysplasia (hctd) are known to be subject to infectious and inflammatory diseases due to peculiarities of their immune system. we studied 181 patients with hctd depending on thyroid hormone levels and vegetative dysfunction. hctd was shown to be associated with a significant decrease of igm levels and increase of circulating immune complexes. the igg level in patients with mitral valve prolapse (mvp), anomalous chord localization, and combination of mpv and t ... | 2012 | 23285764 |
| [the influence of subclinical thyroid dysfunction on cardiac hemodynamic and electrophysiological parameters in patients with coronary heart disease and paroxysmal atrial fibrillation]. | the study included 58 patients with chd and paroxysmal atrial fibrillation divided into 2 groups depending on thyroid hormone and thyrotropin levels. group 1 was comprised of 24 patients with subclinical hypothyroidism, group 2 of 18 ones with subclinical hyperthyroidism. control group consisted of l6 patients with chd, paroxysmal atrial fibrillation and normal thvroid function. it was shown that patients with chd, paroxysmal atrial fibrillation and subclinical thyrotoxicosis had t3 and t4 level ... | 2012 | 23285759 |
| [radio and chemotherapy in gallbladder cancer: a latin american consensus]. | no randomized controlled trials have been conducted in gallbladder cancer to establish standard treatments. we therefore conducted the first latin american consensus meeting for the management of gallbladder cancer. in this paper we report the conclusions of the experts' panel for (neo) adjuvant treatment of resectable gallbladder cancer. these are based on the review of the literature, the discussion of the participating experts and the vote of the assistants (surgical oncologists, medical onco ... | 2012 | 23282782 |
| endoscopic ultrasound in restaging and predicting pathological response for advanced gastric cancer patients after neoadjuvant chemotherapy. | aim: to evaluate the role of endoscopic ultrasound (eus) in restaging and predicting response after neoadjuvant chemotherapy in patients with advanced gastric cancer. methods: in all, 48 advanced gastric cancer patients were recruited from june 2007 to december 2010 after providing their written, informed consent. all patients underwent an eus before and after three cycles of neoadjuvant chemotherapy (folfox 6), and then a radical resection was performed 3-4 weeks after chemotherapy. the results ... | 2012 | 23279745 |
| comparison between cranial thoracic intervertebral disc herniations in german shepherd dogs and other large breed dogs. | cranial thoracic intervertebral disc herniations have been reported to be rare in dogs due to the presence of the intercapital ligament, however some studies have proposed they may not be uncommon in german shepherd dogs. the purpose of this retrospective study was to compare cranial thoracic intervertebral disc herniations in german shepherd dogs and other large breed dogs (control group). medical records at the ontario veterinary college were searched for german shepherd dogs and other large b ... | 2012 | 23278950 |
| cryoelectron microscopy analysis of small heat shock protein 16.5 (hsp16.5) complexes with t4 lysozyme reveals the structural basis of multimode binding. | small heat shock proteins (shsps) are ubiquitous chaperones that bind and sequester non-native proteins preventing their aggregation. despite extensive studies of shsps chaperone activity, the location of the bound substrate within the shsp oligomer has not been determined. in this paper, we used cryoelectron microscopy (cryoem) to visualize destabilized mutants of t4 lysozyme (t4l) bound to engineered variants of the small heat shock protein hsp16.5. in contrast to wild type hsp16.5, binding of ... | 2012 | 23277356 |
| thyroid hormones and erythrocyte indices in a cohort of euthyroid older subjects. | hypothyroidism is associated with normocytic anaemia. indeed, a limited number of studies have shown significant associations between free thyroxin (t4) and erythrocyte indices. these studies did not include vitamin b12, folic acid, iron and renal function in the analyses. we therefore studied the association between thyroid hormones and erythrocyte indices in a population-based cohort of older euthyroid subjects, with adjustment for major confounding parameters. | 2012 | 23276452 |
| eplt4 proteinaceous elicitor produced in pichia pastoris has a protective effect against cercosporidium sofinum infections of soybean leaves. | a complementary dna library was constructed from the mycelium of trichoderma asperellum t4, and a highly expressed gene fragment named eplt4 was found. in order to find a more efficient and cost-effective way of obtaining eplt4, this study attempted to produce eplt4 using a pichia pastoris expression system. the gene encoding eplt4, with an additional 6-his tag at the c-terminus, was cloned into the yeast vector ppic9k and expressed in the p. pastoris strain gs115 to obtaining more protein for t ... | 2012 | 23271623 |
| [clinical analysis of patients with stage iv ( colorectal cancer after palliative resection of primary tumor]. | to investigate the independent predictors of postoperative mortality, morbidity, and long-term survival in patients with stage iv ( colorectal cancer. | 2012 | 23268278 |
| a survey of host range genes in poxvirus genomes. | poxviruses are widespread pathogens, which display extremely different host ranges. whereas some poxviruses, including variola virus, display narrow host ranges, others such as cowpox viruses naturally infect a wide range of mammals. the molecular basis for differences in host range are poorly understood but apparently depend on the successful manipulation of the host antiviral response. some poxvirus genes have been shown to confer host tropism in experimental settings and are thus called host ... | 2012 | 23268114 |
| [evaluation of chemoradiotherapy for stage ii and iii( non-t4) esophageal cancer]. | we retrospectively evaluated the clinical efficacy of chemoradiotherapy for surgically resectable stage ii and iii (non-t4) esophageal cancer. | 2012 | 23267987 |
| [complete response obtained by preoperative chemotherapy in a case of t4 rectal cancer]. | a 48-year-old man, who had presented with anal pain and cloudy urine, was referred to our hospital. colonoscopy showed a type 2 circular tumor at the higher rectum, and a diagnosis of well-differentiated adenocarcinoma was made by biopsy. ct demonstrated increased thickness of the rectum wall, an equivocal boundary between the rectum and the bladder, and abnormal gas production in the bladder. following diagnosis of t4 rectal cancer, preoperative chemotherapy was initiated with the aim of downst ... | 2012 | 23267941 |
| [a case of advanced hepatocellular carcinoma with tumor thrombosis in the main trunk of the portal vein successfully treated by multidisciplinary therapies]. | we report a case of advanced hepatocellular carcinoma(hcc) with tumor thrombosis in the main trunk of the portal vein successfully treated by multidisciplinary therapies. this case is that of a 61-year-old man with loss of appetite and weight loss. the abdominal computed tomography revealed an early enhanced and late wash-out lesion in the right hepatic lobe and tumor thrombosis in the major trunk of the portal vein. we diagnosed advanced hcc related to chronic hepatitis c [t4 (vp4) n0m0, stage ... | 2012 | 23267913 |
| effect of corticosterone on growth and welfare of broiler chickens showing long or short tonic immobility. | tonic immobility (ti) test is commonly used to assess fear. animals showing different ti durations demonstrate distinct behavior and biochemical responses to stress. however, less is known about how ti phenotype affects growth and welfare of domestic fowl. in this study, broiler chickens (gallus gallus) were classified into short and long ti duration (sti and lti) phenotypes and treated chronically with vehicle (con) or corticosterone (cort). sti broilers demonstrated significantly higher growth ... | 2012 | 23266338 |
| surgical treatment of ossification of the ligamentum flavum associated with dural ossification in the thoracic spine. | between january 2006 and december 2009, dural ossification (do) was found intraoperatively in 26 of 98 patients with thoracic spinal stenosis due to ossification of the ligamentum flavum (olf). mri showed single-level (n = 2), two-level (n = 8) and multilevel (n = 16) areas of low signal intensity in the ligamentum flavum of the thoracic spine. of the 68 ossified segments in the study population, 11 (16.2%) were located in the upper thoracic spine (t1-t4), nine (13.2%) were located in the midtho ... | 2012 | 23266313 |
| the prognostic significance of hypoxia inducing factor 1-α in oropharyngeal cancer in relation to human papillomavirus status. | this study examines the prognostic significance of hypoxia inducing factor-1α (hif-1α) expression in relation to human papillomavirus (hpv) status in oropharyngeal squamous cell carcinoma (scc). | 2012 | 23266008 |
| the incidence of interval cancers in the german mammography screening program: results from the population-based cancer registry in north rhine-westphalia. | cancer screening programs must meet high standards for quality and effectiveness, because many healthy persons need to be screened to detect relatively few cases of cancer. in this study, we use the rate of interval cancers as an important surrogate indicator for evaluating the german mammography screening program (msp). | 2012 | 23264826 |