| treatment of hypothyroidism due to iodine deficiency using daily powdered kelp in patients receiving long-term total enteral nutrition. | we investigated thyroid function and urinary iodine concentration (uic) in seven patients with severe motor intellectual disabilities. all seven received total enteral nutrition (ten) for more than three years with a daily iodine intake of less than 20 µg. they were diagnosed as hypothyroidism due to iodine deficiency (hid) because of high tsh levels (7.6-82.3 µiu/ml), lower free t4 (ft4 0.4-1.5 ng/dl), negative anti-thyroid antibodies (anti-thyroglobulin antibody, anti-thyroidal peroxidase anti ... | 2011 | 23926395 | 
| nutritional and toxicological assessment of white-rot fermented animal feed. | the fungal fermented wheat straws as animal feeds have been evaluated for its toxicological and nutritional status in male rats (holtzman strain). digestibility of dry matter and other nutrients as well as fiber fractions were found significantly higher (p < 0.05) in straw fermented with either ganoderma sp. rckk02 (t3) or crinipellis sp. rck-1 (t4) than unfermented straw (t1) or straw fermented with pycnoporus cinnabarinus (t2). the aflatoxin b1, b2, g1 and g2 were either absent or present in p ... | 2011 | 23729880 | 
| changes of serum trace elements, afp, cea, sf, t3, t4 and igf-ii in different periods of rat liver cancer. | based on liver cancer model built in sd rats, the contents of trace elements (cu, fe, zn, ca and mg), afp, cea, sf, th and igf-ii in serum were measured at different stages to explore the molecular changes during the rat liver cancer development. | 2011 | 23357927 | 
| [viability and efects of the probiotic lactobacillus aracaseissp aracasei in chilean low-fat gauda cheese]. | the objective of this study is to infer the survival of the probiotic lactobacillus paracasei ssp paracasei added during the processing of low-fat gouda cheese, during the maturation (21 days) and the commercialization (14 days), in order to see the influence that this organism has on the quality of the product. the treatments were: ti (control): gouda with normal fat content; t2: low fat gouda cheese (qgs) t3: qgs, with additional probiotic added with the initial culture; t4: qgs, with the prob ... | 2011 | 23094525 | 
| expression of p-akt and p-mtor in a large series of bronchopulmonary neuroendocrine tumors. | bronchopulmonary neuroendocrine tumors (bp-nets) are separated into four subgroups: typical carcinoid tumor (tc), atypical carcinoid tumor (ac), large-cell neuroendocrine carcinoma (lcnec) and small-cell lung carcinoma (sclc). the signaling pathway involving akt/mammalian target of rapamycin (mtor) is crucial to the regulation of cell growth, proliferation and survival, and is frequently activated in human cancers. consequently, mtor is considered an attractive target for anticancer agents. the  ... | 2011 | 22977576 | 
| subclinical hypothyroidism in childhood obesity and its correlation with lipoproteins. | there is an ongoing debate regarding the influence of subclinical hypothyroidism on body mass index. the objectives of the study were (i) to determine whether levels of thyroid stimulating hormone (tsh) are elevated in obese children, (ii) to compare the serum levels of triiodothyronine (t3) and thyroxine (t4) in obese with non-obese and (iii) to examine the association of subclinical hypothyroidism with lipoproteins and body mass index. | 2011 | 22783686 | 
| chemoradiation in advanced head and neck cancers: a comparison of two radiosensitizers, paclitaxel and cisplatin. | to compare the locoregional control rates, survival outcome and toxicity profiles between two groups of patients of squamous cell carcinoma (scc) of head and neck (stage iii & iv) receiving concomitant chemo-radiotherapy with paclitaxel and cisplatin. a prospective study was done on 94 previously untreated patients of histopathologically proved squamous cell carcinoma of head and neck region-ajcc stage iii & iv (t3 & t4 with n0 -n3, m0) treated with concomitant chemoradiation. the patients were  ... | 2011 | 22754800 | 
| surgical treatment of papillary thyroid carcinoma. | papillary carcinoma accounts for 85% of differentiated thyroid cancers. we witness a yearly increased incidence and this is may be, in part, due to the increasing use of neck ultrasonography. certain histologic subtypes of papillary carcinoma have a worse prognosis related to vascular invasion, invasion into extrathyroidal tissues, extensive tumor necrosis and/or mitoses. adequate surgery is the most important treatment variable influencing prognosis, while radioactive iodine treatment, tsh supp ... | 2011 | 22746009 | 
| successful bortezomib treatment in combination with dexamethasone and thalidomide for previously untreated epidural plasmacytoma. | epidural plasmacytoma is a rare clinical entity of plasma cell neoplasms. the optimal management of extra medullary plasmacytoma remains unclear, particularly for bulky masses. in this study, we report the case of a 35-year-old male who presented with the inability to walk, urinary incontinence and superficial and deep sensory disturbance. spinal magnetic resonance imaging revealed a large epidural mass compressing the spinal cord at the level of t2-t4. the patient underwent surgical t2-t4 verte ... | 2011 | 22740951 | 
| copy number changes of crisp3 in oral squamous cell carcinoma. | the aim of this study was to identify tumor suppressor genes (tsgs) in oral squamous cell carcinoma (oscc) using whole-genome analysis of microarray technology and real-time quantitative polymerase chain reaction (qpcr). we applied whole-genome analysis of tsgs in the specimens from 3 patients of oscc by microarray technology. a total of 11 genes, crisp3, scgb3a1, agr2, pip, c20orf114, tff1, stath, azgp1, muc7, dmbt1 and loc389429, were found to be down-regulated, and 2, matrix metallopeptidase  ... | 2011 | 22740859 | 
| correlation of metabolism/hypoxia markers and fluorodeoxyglucose uptake in oral squamous cell carcinomas. | the objective of this study was to analyze the relationship between the uptake of (18)f-2-fluoro-2-deoxy-d-glucose (fdg) by positron emission tomography-computerized tomography (pet-ct) and glucose metabolism/hypoxia markers in oral squamous cell carcinoma (oscc). | 2011 | 22676927 | 
| triiodothyronin, thyroxine and thyrotropin in vitiligo. | vitiligo is a common pigmentary disorder of the skin, affecting individuals globally. not only is this ailment psychologically incapacitating, it also has a high incidence of autoimmunity, signifying that its manifestations may be the portrayal of dysfunction of immune system. | 2011 | 22610860 | 
| incidence of incidental carcinoma gall bladder in cases of routine cholecystectomy. | carcinoma of gall bladder is the most common malignancy of the billiary tract. most of the cases are diagnosed as an incidental case among patients undergoing cholecystectomy. | 2011 | 22610859 | 
| failure patterns in patients with esophageal cancer treated with definitive chemoradiation. | local failure after definitive chemoradiation therapy for unresectable esophageal cancer remains problematic. little is known about the failure pattern based on modern-day radiation treatment volumes. we hypothesized that most local failures would be within the gross tumor volume (gtv), where the bulk of the tumor burden resides. | 2011 | 22565611 | 
| how common is hypothyroidism after external radiotherapy to neck in head and neck cancer patients? | to identify the occurrence of clinical and subclinical hypothyroidism among head and neck cancer patients receiving radiation to the neck and to justify routine performing of thyroid function tests during follow-up. | 2011 | 22557780 | 
| [functional assessment of the different types of anterior cruciate ligament plasty used at the xoco general hospital arthroscopy service]. | currently, anterior cruciate ligament lesions have an increased frequency; their management is predominantly surgical; there are several functional assessment systems. | 2011 | 22512111 | 
| suppression of seizure by cathodal transcranial direct current stimulation in an epileptic patient - a case report -. | epilepsy is an intractable disease, though many treatment modalities have been developed. recently, noninvasive transcranial direct current stimulation (tdcs), which can change brain excitability, was introduced and has been applied for therapeutic purposes regarding epilepsy. a suppression of seizures was experienced by cathodal tdcs in a medication refractory pediatric epileptic patient. the patient was an 11-year-old female who had focal cortical dysplasia of the cerebral hemisphere. the pati ... | 2011 | 22506177 | 
| craniofacial resection for sinonasal malignant tumors: statistical analysis of surgical outcome over 17 years at a single institution. | we present a retrospective analysis of surgical outcome of sinonasal malignant tumors. overall survival (os), disease-specific survival (dss), local control (lc), and disease-free survival (dfs) were calculated in 32 patients. prognostic factors for survival and functional outcomes were investigated. the median follow-up period was 70 months. at 5 years, os, dss, lc, and dfs rates were 0.722, 0.745, 0.851, and 0.707, respectively. prognostic factors for poor os were involvement of the frontal si ... | 2011 | 22470267 | 
| concomitant chemoradiotherapy as a standard treatment for squamous cell carcinoma of the temporal bone. | we sought to characterize the effectiveness of concomitant chemoradiotherapy (ccrt) for patients with squamous cell carcinoma of the temporal bone. we performed a retrospective chart review of 14 patients with cancer of the temporal bone who were provided initial treatment in our hospital from december 2001 to november 2008. four patients with stage i tumors were treated by radiation therapy alone or with oral administration of s1. one patient with a stage ii tumor was treated by radiation thera ... | 2011 | 22451818 | 
| single-molecule studies of viral dna packaging. | assembly of many dsdna viruses involves packaging of dna molecules into pre-assembled procapsids by portal molecular motor complexes. techniques have recently been developed using optical tweezers to directly measure the packaging of single dna molecules into single procapsids in real time and the forces generated by the molecular motor. three different viruses, phages phi29, lambda, and t4, have been studied, revealing interesting similarities and differences in packaging dynamics. single-molec ... | 2011 | 22440623 | 
| the effects of short-term manipulation of thyroid hormone status coinciding with primary wool follicle development on fleece characteristics in merino sheep. | thyroidectomy surgery performed late in gestation results in perturbations in wool follicle development in foetal sheep, showing the importance of thyroid hormones for wool follicle development. the aim of this study was to determine the influence of transient manipulation of thyroid hormone status at a time corresponding with foetal primary wool follicle initiation. pregnant merino ewes (n = 12 per treatment) were treated daily between gestational days 55 and 64 with control (vehicle), exogenou ... | 2011 | 22440286 | 
| shelf life study of fresh celery (apium graveolens l.) grown under different nitrogen fertilization treatments. | nitrogen fertilization is useful for obtaining higher growth and quality of productions, and the use of nitrogen fertilization is widespread. to evaluate the influence of nitrogen-rich fertilizers on quality characteristics of celery, shelf life tests of celery grown with 2 levels of nitrogen and 2 different nitrogen fertilizers were performed. the treatments of the celery samples were identified as follows: t1, mineral nitrogen (80 kg ha(-1)); t2, mineral nitrogen (120 kg ha(-1)); t3, organic n ... | 2011 | 22417367 | 
| study of the effects of hydrogen cyanide exposure in cassava workers. | hydrogen cyanide is the chemical responsible for tissue hypoxia. chronic exposure to hcn may cause neurological, respiratory, cardiovascular and thyroid defects. onset of symptoms depends on dose and duration of exposure. large scale of cassava processing could be disastrous due to discharge of hydrocyanic acid into the air. cassava processing is the major industrial work in and around salem. hence the present study is taken to assess the effects of hcn exposure in cassava workers. | 2011 | 22412292 | 
| [subclinical hypothyroidism and cardiovascular risk factors]. | to determine the prevalence of subclinical hypothyroidism in the general population of an urban health center and describe the clinical characteristics and cardiovascular risk factors in patients with subclinical hypothyroidism. | 2011 | 22411383 | 
| extradural en-plaque spinal meningioma with intraneural invasion. | extradural spinal meningiomas are rare. our understanding of purely extradural spinal meningiomas is incomplete because most reports rarely differentiate purely extradural meningiomas from extradural meningiomas with an intradural component. occasionally, reports have described involvement of the adjacent nerve root, but there has never been a description of an extradural meningioma that actually infiltrates the nerve root. | 2011 | 22405399 | 
| an atypical case of retropharyngeal abscess with long blind tract treated with ryle's tube drainage. | a 10 year-old iban girl presented with severe odynophagia for 4 days and subcutaneous emphysema. clinically, her neck was tender with crepitus. lateral neck radiograph showed multiple linear radiolucent shadows at retropharyngeal space. flexible nasopharyngolaryngoscope revealed a tunnel behind upper oesophagus with slough and there was pooling of saliva at pyriform sinus. feeding via nasogastric tube was started and empirical treatment for fungal and bacterial infection was commenced. subsequen ... | 2011 | 22390112 | 
| [resistance to thyroid hormone and hashimoto's thyroiditis]. | resistance to thyroid hormone (rth) is a rare condition characterized by elevation of thyroid stimulating hormone (tsh) and thyroid hormones (th). its association with hashimoto's thyroiditis was described in 1993 and occurs in 1 of 1.3 million births. | 2011 | 22385766 | 
| effect of ramadan fasting on body composition and physical performance in female athletes. | the aim of this study was to determine the effect of ramadan fasting on body composition, calorie intake and physical performance in young female athletes undertaking training sessions during ramadan. | 2011 | 22375235 | 
| management of severe class ii division 1 malocclusion: a case report. | to describe the two-phase treatment of a preadolescent boy with a severe skeletal class ii division 1 malocclusion with vertical maxillary excess and spaced upper incisors. | 2011 | 22372276 | 
| prevalence of subclinical hypothyroidism among patients with acute myocardial infarction. | introduction. subclinical hypothyroidism (sch) is defined as a serum thyroid-stimulating hormone (tsh) level above the upper limit of normal despite normal levels of serum free thyroxine. there is growing evidence that sch is associated with increased cardiovascular risk. we tried to investigate prevalence of sch in acute myocardial infarction patients. methods and results. we evaluate free t3, free t4, and tsh levels of 604 patients (age 58.4) retrospectively, who have been admitted to the coro ... | 2011 | 22363888 | 
| [ileus caused by metastasis of cutaneous malignant melanoma: case report]. | in this case report we describe rare metastatic appearance of cutaneous malignant melanoma ( mm) in small intestine followed by clinical appearance of acute surgical abdomen. a 42-year old women operated in our hospital in april 2009. due to unusual naevus on her right arm. pathologicaly it was mm grossly 1.5 cm, microscopically breslow 11 mm, clark's level iv (t4), number of mitosis 1.4 per mm2, without ulcerations. she was sent to continue treatment at the national referal center for melanoma  ... | 2011 | 22359897 | 
| on-pump coronary artery bypass graft surgery: biochemical, hormonal and cellular features. | the authors sought to assess biochemical, hormonal and cellular repercussions from use of cardiopulmonary bypass (cpb) in coronary artery bypass graft (cabg) surgery. | 2011 | 22358266 | 
| reversal of difluoromethylornithine effects by the administration of putrescine in rats. | to assess the reversal of di-fluoromethyl ornithine (dfmo) effects by administration of putrescine on thyroid glands in rats. | 2011 | 22355995 | 
| effects of extrusion and heat treatment on the mechanical properties and biocorrosion behaviors of a mg-nd-zn-zr alloy. | mechanical properties at room temperature and biocorrosion behaviors in simulated body fluid (sbf) at 37 °c of a new type of patented mg-3nd-0.2zn-0.4zr (hereafter, denoted as jdbm) alloy prepared at different extrusion temperatures, as well as heat treatment, were studied. the mechanical properties of this magnesium alloy at room temperature were improved significantly after extrusion and heat treatment compared to an as-cast alloy. the results of mechanical properties show that the yield stren ... | 2011 | 22340687 | 
| effects of preoperative ketamine on the endocrine-metabolic and inflammatory response to laparoscopic surgery. | ketamine is hypothesized to reduce perioperative endocrine-metabolic and inflammatory responses in cardiac surgery patients. this randomized, placebo-controlled, double-blind study was performed to determine whether perioperative endocrine-metabolic and inflammatory responses are attenuated by preoperative administration of ketamine to healthy females receiving elective laparoscopic surgery. | 2011 | 22340231 | 
| comparison of compensatory sweating and quality of life following thoracic sympathetic block for palmar hyperhidrosis: electrocautery hook versus titanium clip. | video-assisted thoracic sympathetic block is an effective, safe, and minimally invasive method for treatment of primary hyperhidrosis. the purpose of this study was to decide which one of using electrocautery hook and titanium clip is the appropriate procedure for primary palmar hyperhidrosis by assessing the compensatory sweating (cs) and quality of life (qol) of patients after sympathetic block. | 2011 | 22340165 | 
| [identification of nucleolar localization signal sequence of tumor metastasis suppressor gene-1]. | to identify the putative specific localization signal sequence of tumor metastasis suppressor gene-1 (tmsg-1) and to explore the mechanism of subcellular localization of tmsg-1 protein. | 2011 | 22336162 | 
| [endoscopic surgery and endoscopy-assisted surgery for the malignant transformation of sinonasal inverted papilloma]. | to investigate malignant transformation of sinonasal inverted papilloma (sip) treated by nasal endoscopic and endoscopy-assisted surgery. | 2011 | 22336018 | 
| [the clinical application of monitored anesthesia care in percutaneous dilatational tracheostomy]. | to investigate the changes in hemodynamics and depth of anesthesia under monitored anesthesia care (mac) in patients undergoing percutaneous dilatational tracheostomy (pdt). | 2011 | 22332577 | 
| breast cancer in women under 40 years of age. | it is widely believed that breast cancer in young women is characterized by a relatively unfavorable prognosis and unusual pathological features. the aim of this study was to investigate clinicopathological and biological characteristics in young patients with breast cancer. | 2011 | 22331714 | 
| clinicopathologic significance of gastric adenocarcinoma with neuroendocrine features. | composite neuroendocrine-exocrine carcinomas are malignancies that have two distinct components residing within the same tumor: an adenocarcinomatous portion and a neuroendocrine portion. this is rare in gastric cancers; however, poorly differentiated adenocarcinomas can sometimes reveal evidence of neuroendocrine features (nef) or be 'mixed endocrine and exocrine carcinomas'. this study aimed to review nef in gastric adenocarcinoma and to evaluate its prognostic significance. | 2011 | 22324009 | 
| [clinical observation of visual quality after implantation of toric intraocular lens]. | to observe the visual quality after implantation of acrysof toric intraocular lens (iol) in cataract patients. | 2011 | 22321501 | 
| spontaneous vacuolar degeneration of the thyroid follicular epithelium in cynomolgus monkeys. | vacuolar degeneration of the thyroid follicular epithelium was observed in two untreated female cynomolgus monkeys assigned to control groups. in light microscopy, large vacuoles containing a homogenous substance occupied the basal region of the epithelium, and the nuclei had shifted toward the apical region. the vacuoles showed negative reactions to pas and thyroglobulin. electron microscopic observation revealed dilatation of the rough endoplasmic reticulum corresponding to the vacuoles. the p ... | 2011 | 22319235 | 
| concomitant radiotherapy and chemotherapy for high-risk nonmelanoma skin carcinomas of the head and neck. | background. to report on the use and feasibility of a multimodality approach using concomitant radiotherapy and chemotherapy in patients with high-risk nonmelanoma skin carcinoma (nmsc) of the head and neck. methods. records of patients with nmsc of the head and neck who received concomitant crt at the university of north carolina between 2001 and 2007 were reviewed. results. fifteen identified patients had at least one of the following high-risk factors: t4 disease (93%), unresectability (60%), ... | 2011 | 22312508 | 
| central hypothyroidism following chemotherapy for acute lymphoblastic leukemia. | it has been suggested that chemotherapy per se might impair the hypothalamus-pituitary-thyroid axis of childhood cancer survivors. | 2011 | 22308840 | 
| neurodevelopment of preterm infants born at 28 to 36 weeks of gestational age: the role of hypothyroxinemia and long-term outcome at 4 years. | hypothyroxinemia in premature neonates may affect long-term neurodevelopment. | 2011 | 22308839 | 
| normal thyroid function in young adults who were born very preterm. | there is some evidence for elevated thyrotropin (tsh) levels in children born preterm, but follow-up studies into adulthood are lacking. we tested whether thyroid function in young adults born at a gestational age < 32 weeks, with either an appropriate (appropriate for gestational age, aga) or low birth weight for gestational age (small for gestational age, sga), differed from that in age-matched controls. we made our measurements when the study participants reached 21 years of age. serum concen ... | 2011 | 22308837 | 
| [establishment of gynecological asthenia cold syndrome model]. | to establish the model of gynecological asthenia cold syndrome by simulating the etiology of gynecological asthenia cold syndrome depending on 'pathogenic cold impairing yang" in chinese medicine theory. | 2011 | 22303717 | 
| [effect of shenfu injection on the erythrocyte immune function of patients undergoing cardiopulmonary bypass]. | to observe the effect of shenfu injection (sfi) on erythrocyte immunity function of patients undergoing cardiopulmonary bypass (cpb). | 2011 | 22303706 | 
| patterns of differentiated thyroid cancer in baluchistan province of pakistan: some initial observations. | the incidence of thyroid cancer is increasing in several countries. the main objective of this retrospective study was to find and describe province-specific estimates of incidence in males and females by age groups for differentiated thyroid cancer (dtc). this study reports on 87 cases of dtc from baluchistan province of pakistan treated with post operative radioiodine at the center for nuclear medicine and radiotherapy (cenar) quetta from january 2003 to december 2009. the patient data has bee ... | 2011 | 22299551 | 
| effect of anesthesia on the changes in the hormones levels during and after transvesical prostatectomy. | hypovolemia and pain are direct stimulators of hormonal response to trauma. thus, neuroendocrine, metabolic and inflammatory aspects of the injury are part of an overall "stress response". in particular, it manifests in patients undergoing surgical intervention. these reactions can occur with trauma, burns, severe infections and physical exertion. metabolic and neuroendocrine response to surgical intervention depends on several factors, such as severity and duration of the surgical trauma, patie ... | 2011 | 22299297 | 
| nestin expression associates with poor prognosis and triple negative phenotype in locally advanced (t4) breast cancer. | nestin, an intermediate filament protein, has traditionally been noted for its importance as a neural stem cell marker. however, in recent years, expression of nestin has shown to be associated with general proliferation of progenitor cell populations within neoplasms. there is no reported study addressing nestin expression in t4 breast cancer patients. thus, the aim of the present study was to investigate, through immunohistochemistry, the expression and distribution of nestin in t4 breast canc ... | 2011 | 22297445 | 
| [clinical observation of injection of dexmedetomidine in anaesthesia for esophageal cancer operation]. | to investigate the effects of administration of dexmedetomidine in anaesthesia for esophageal cancer operation. | 2011 | 22295535 | 
| the content of cadmium, cobalt and nickel in laryngeal carcinoma. | the aim of the study was to determine the content of cadmium (cd), cobalt (co) and nickel (ni) in the samples from laryngeal carcinoma in comparison with the level of these elements in the samples of healthy mucous membrane from the same larynx. | 2011 | 22295038 | 
| clinical and pathological response rates of docetaxel-based neoadjuvant chemotherapy in locally advanced breast cancer and comparison with anthracycline-based chemotherapies: eight-year experience from single centre. | the administration of neoadjuvant chemotherapy (nact) prior to local therapy is advantageous for women with locally advanced breast cancer (labc), since it can render inoperable tumors resectable and can increase rates of breast conservative surgeries. | 2011 | 22293253 | 
| [comparison of the maternal and neonatal effects of combined spinal-epidural block and spinal block for cesarean section]. | combined spinal-epidural block (cseb) has gained increasing interest as it combines the reliability of a spinal block (sb) and the flexibility of an epidural block in cesarean section. we investigated the maternal and fetal effect of cseb against sb in cesarean operation. | 2011 | 22290681 | 
| [capacities of diagnostic volumetric multislice spiral computed tomography in the diagnosis of gastric cancer]. | in the period 2009 to 2010, diagnostic multislice spiral computed tomography (msct) was carried out in 49 patients with gastric cancer. the efficiency of dynamic msct in detecting a tumor and determining its locoregional extent was evaluated. the results of dynamic msct were compared with those of postoperative histological examination. the possibility of detecting gastric cancer by dynamic msct was ascertained to depend on the depth of tumor invasion and to average 29, 71, 72, and 77% for t1, t ... | 2011 | 22288146 | 
| severe rhabdomyolysis and acute renal failure in an adolescent with hypothyroidism. | hypothyroidism has been reported rarely as the cause of rhabdomyolysis in adults and children. we present here a non-compliant adolescent with a diagnosis of hypothyroidism who developed rhabdomyolysis and acute renal failure with no additional predisposing factor. a 13-year-old girl with a previous history of hypothyroidism due to thyroid hypoplasia presented with generalized myalgia, malaise, vomiting, and oliguria lasting for three days. neurological examination revealed bilateral marked weak ... | 2011 | 22272466 | 
| double-probe signal enhancing strategy for toxin aptasensing based on rolling circle amplification. | on the basis of aptamer-based rolling circle amplification (rca) and magnetic beads (mbs), a highly sensitive electrochemical method was developed for the determination of ochratoxin a (ota). initially, an amino-modified capture dna was immobilized onto mbs for the following hybridization with an ota aptamer and a phosphate labeled padlock dna. in the presence of ota, the aptamer would dissociate from the bioconjugate, and the padlock dna would subsequently hybridize with the capture dna to form ... | 2011 | 22270050 | 
| segmental lesions in pityriasis rosea: a rare presentation. | a 34-year-old nonpregnant woman noted a mildly pruritic skin lesion on her right breast for 1 week following an episode of coryza, malaise, and low-grade fever of 3 days' duration. the latter symptoms subsided without any treatment. ketoconazole cream prescribed by her family physician did not resolve the breast eruption after 1 week, so was stopped. a week later, multiple skin lesions erupted suddenly on her right chest wall starting near the herald patch in midaxillary line and spread distally ... | 2011 | 22256628 | 
| effects of fermented mushroom (flammulina velutipes) by-product diets on growth performance and carcass traits in growing-fattening berkshire pigs. | this study was conducted to investigate effects of fermented mushroom (flammulina velutipes) by-product diets on the growth performance and carcass traits in growing-fattening berkshire pigs. the fermented diets mainly contained 40.0% mushroom by-product, 20.0% formula feed, 26.0% rice bran and supplemental 0.1% probiotics. the mixed ingredients were fermented for 5days at room temperature. berkshire pigs (n=225) were divided into five groups and three replications. the basal diets (c) were subs ... | 2011 | 22250740 | 
| [spectroscopic characteristics of dissolved organic matter in water from typical area of taihu lake]. | fluorescence spectroscopy, uv spectroscopy, and multiple uv parameters were applied to determine and analyze the dissolved organic matter (dom) in water of taihu lake, in order to find out the sources and influencing factors of dom in water from typical areas of taihu lake. the results showed that the components of dom in water from different lake areas displayed some regional characteristics. the contents of macro-molecules matters with complex structures and humic substances in water from samp ... | 2011 | 22242509 | 
| [clinical analysis of cervical lymph node metastasis of hypopharyngeal carcinoma]. | to investigate the pattern of cervical lymph node metastasis in hypopharyngeal carcinoma. | 2011 | 22242474 | 
| long-term survival after lung-sparing total pleurectomy for locally advanced (international mesothelioma interest group stage t3-t4) non-sarcomatoid malignant pleural mesothelioma. | there is a body of opinion that advocates extrapleural pneumonectomy (epp) as the only radical treatment option for locally advanced (t3/t4) malignant pleural mesothelioma (mpm). we tested the hypothesis that lung-sparing total pleurectomy (lstp) can be as effective as epp in locally advanced mpm with reduced risk. | 2011 | 22219469 | 
| significance of a new fluorodeoxyglucose-positive lesion on restaging positron emission tomography/computed tomography after induction therapy for non-small-cell lung cancer. | restaging of patients with locally advanced non-small-cell lung cancer (nsclc) is of paramount importance, since only patients with down-staging after induction therapy will benefit from surgery. in this study, we assessed the aetiology of new (18)fluoro-2-deoxy-d-glucose (fdg)-positive focal abnormalities on restaging positron emission tomography/computed tomography (pet/ct) in patients with a good response after induction chemotherapy in the primary tumour and lymph nodes. | 2011 | 22219415 | 
| the role of adjuvant in mediating antigen structure and stability. | the purpose of this study was to probe the fate of a model antigen, a cysteine-free mutant of bacteriophage t4 lysozyme, to the level of fine structural detail, as a consequence of its interaction with an aluminum (al)-containing adjuvant. fluorescence spectroscopy and differential scanning calorimetry were used to compare the thermal stability of the protein in solution versus adsorbed onto an al-containing adjuvant. differences in accessible hydrophobic surface areas were investigated using an ... | 2011 | 22213631 | 
| effect of excess levels of lysine and leucine in wheat-based, amino acid-fortified diets on the mrna expression of two selected cationic amino acid transporters in pigs. | an experiment was conducted to evaluate the effect of excess levels of leu and lys on the expression of b(0,+) and cat-1 mrna in jejunum, liver and the muscles longissimus dorsi (ldm) and semitendinosus (stm). twenty pigs with an average initial bw of 16.4 ± 1.7 kg were used in a randomized complete block. dietary treatments (t) were as follows: t1, basal diet; t2, basal plus 3.5 g l-lys/kg diet; t3, basal plus 1.5 g l-leu/kg diet; t4, basal plus 3.5 g l-lys plus 1.5 g l-leu/kg diet. diets in t1 ... | 2011 | 22211733 | 
| the correlation between type of anesthesia and the hormones levels during and after transvesical prostatectomy. | surgical intervention and anesthesia procedure lead to a series of hormonal changes in the organism, which is mainly attributed to catecholamine response to stress. surgical intervention is resulting in significant changes in neuroendocrine regulation, metabolism and physiological functions, as part of the overall response to stress. research aim: the aim of this study was to determine and evaluate the levels of hormones in patients undergoing transvesical prostatectomy under general or local an ... | 2011 | 23408784 | 
| management of the stiff shoulder. a prospective multicenter comparative study of the six main techniques in use: 235 cases. | stiffness in the shoulder is a frequent symptom associated with a number of clinical entities whose management remains inadequately defined. | 2011 | 22036993 | 
| comparison of short-term outcomes and perioperative systemic immunity of laparoscopy-assisted and open radical gastrectomy for gastric cancer. | to compare the perioperative systemic immunity of laparoscopy-assisted and open radical gastrectomy for gastric cancer. | 2011 | 23672753 | 
| potentially pathogenic free-living amoebae (fla) isolated in spanish wastewater treatment plants. | this work studies the characterization of pathogenic free-living amoebae (fla) from sewage effluents. some of them, such as acanthamoeba, naegleria, hartmannella, sappinia, balamuthia and paravahlkampfia have been reported as a cause of diseases in humans. therefore, the study of their habitats and their pathogenicity has become necessary. the population of potentially pathogenic fla was analysed in five spanish wastewater treatment plants. five of the seven fla isolated were identified as genus ... | 2011 | 23761343 | 
| congenital hypothyroidism with severe hypoganglionosis of the colon in a 10 years old girl, a case report. | we present a case report of congenital hypothyroidism in a ten year old ethiopian child, who presented after chronic constipation and abdominal distension since early infancy. she had been diagnosed to have sever hypoganglionosis of the colon at age of eight years, based on histopathological examination. she has short stature, and associated history of delayed dental eruption and shedding. barium enema study and radiography of extremity showed evidences of hypothyroidism. laboratory evaluation a ... | 2011 | 23409402 | 
| [ear carcinomas in department of otolaryngology of the medical university of warsaw in years 2004-2008]. | ear carcinoma constitutes 0.5% of all cancers of the head and neck hardly, however with poor prognosis. in the study we use university of pittsburgh staging system. this study is retrospective analysis of the surgical treatment outcomes of the patients with external and middle ear carcinomas in the ent department at the medical university of warsaw in years from 2004 to 2008. histopatologicallly, there were:18 squamous cell carcinoma, 17 basal cell carcinoma, 2 neuroendocrine carcinoma, basal ce ... | 2011 | 22000249 | 
| efficacy of soy protein isolate as a fat replacer on physico-chemical and sensory characteristics of low-fat paneer. | the nutritional and textural properties of low fat paneer using soy protein isolate (spi) as fat replacer was investigated. the physico-chemical and sensory characteristics of 4 types of paneer made of low-fat milk (3% milk fat (mf) and 10% solids-not-fat (snf)) and spi of 0 (t1), 0.1 (t2), 0.2 (t3) and 0.3% spi (t4) were compared with high fat paneer (tc) made of high fat milk (6% mf and 9% snf). cacl2 (0.2%, w/v) was used as coagulant at 75 ± 1°c. increased level of spi in paneer increased yie ... | 2011 | 23572778 | 
| the first phage electron micrographs. | the first phage electron micrographs were published in 1940 in germany and proved the particulate nature of bacteriophages. phages and infected bacteria were first examined raw and unstained. us american scientists introduced shadowing and freeze-drying. phages appeared to be tailed and morphologically heterogeneous. phage types identified by early electron microscopy include enterobacteriophages t4, t1, t7, t5, 7-11, vii and pseudomonas phage pb1. this paper retraces the development of early vi ... | 2011 | 23050215 | 
| cmos conductometric system for growth monitoring and sensing of bacteria. | we present the design and implementation of a prototype complementary metal-oxide semiconductor (cmos) conductometric integrated circuit (ic) for colony growth monitoring and specific sensing of escherichia coli (e. coli) bacteria. the detection of e. coli is done by employing t4 bacteriophages as receptor organisms. the conductometric system operates by measuring the resistance of the test sample between the electrodes of a two-electrode electrochemical system (reference electrode and working e ... | 2011 | 23851473 | 
| a molecular dynamics study of the interprotein interactions in collagen fibrils. | molecular dynamics simulations of collagen are used to investigate at the atomistic level the nature of the interprotein interactions that are present within a collagen fibril, and which are responsible for the fibril's thermodynamic stability. simulations both of a collagen fibril and of a fully solvated tropcollagen are compared in order to study the interactions that arise between the proteins upon the process of fibrillogenesis. the interactions studied include direct interprotein hydrogen b ... | 2011 | 23526918 | 
| chronic peripheral administration of serotonin inhibits thyroid function in the rat. | we studied the effect of chronic intraperitoneal (ip) administration of serotonin (5-ht) and thyroid function. we injected daily intraperitoneally for 10 days different doses of 5-ht, and measured plasma thyroid hormones and tsh levels. there was a decrease in the plasma levels of t3 and t4 with medium doses of 5-ht (0.2 and 0.4 mg/kg bw for t3, and 0.2 for t4). no effects were evidenced on the plasma levels of tsh. in normal environmental conditions, the site action of 5-ht outside the blood-br ... | 2011 | 23738246 | 
| diagnostic accuracy of fine needle aspiration cytology in thyroid swellings. | proper management of the disease depends upon accurate diagnosis. fine needle aspiration cytology has become the investigation of choice because of its high accuracy, simplicity, minimal-invasiveness, quick result and reliability. | 2011 | 22929705 | 
| a phase ii study of docetaxel, cisplatin and 5- fluorouracil (tpf) in patients with locally advanced head and neck carcinomas. | the combination of cisplatin and 5-fluorouracil (pf) is currently considered a standard and effective regimen for the treatment of advanced head and neck carcinomas. the aim of this study was to evaluate the efficacy and safety of docetaxel, cisplatin and 5-fluorouracil (tpf) in patients with unresectable head and neck carcinomas. | 2011 | 22737461 | 
| [the place of hartmann's resections for some advanced distal rectal cancers]. | adrc involves the adjacent structures and systems in the minor pelvis and the achievement of the importent for the prognosis ro resection is technically challenging. the main problem is to obtain the circumferential clearance and it could require a hysterectomy, vaginal, ureteral, bladder resection or exsenteration. the restoration of the urinary tract integrity is obligatory, but the complications are common if the gut passage is restored too. an additional indication for a two-stage operation  ... | 2011 | 23844461 | 
| retrospective analysis of survival of patients with squamous cell carcinoma of the maxilla after primary resection and elective bilateral neck dissection: an institutional experience. | a retrospective analysis of the 5-year survival rates of patients who underwent treatment for oral squamous cell carcinoma (oscc) of the maxillary region was performed to analyse the prognostic factors for patient's survival. | 2011 | 23483114 | 
| a case of resistance to thyroid hormone with chronic thyroiditis: discovery of a novel mutation (i54v). | resistance to thyroid hormone (rth) is a rare disorder characterized by variable tissue hyporesponsiveness to thyroid hormone, usually caused by mutations in the thyroid hormone receptor beta (trβ). it has been reported that the serum of patients with rth is free of auto-antibodies against thyroglobulin (tg) and thyroid peroxidase (tpo), except in rare cases where coincidental autoimmune thyroiditis is also present. we describe a 13-year-old girl with chronic thyroiditis and rth. this patient ha ... | 2011 | 22937287 | 
| [the state of thyroid system in patients with non-traumatic supratentorial hematomas]. | concentrations of thyroid hormones (thyrotrophic - ttg, t3, t4) were measured with radioimmunological assay in the blood serum of 69 operated patients with supratentorial stroke interbrain hematomas. hematomas were removed using a puncture/ aspiration method with local fibrinolysis. the lethality was 19%. it has been shown that medial hematomas lead to the decrease in ttg secretion while lateral and lobar ones inhibit t4 and t3 synthesis. replacement therapy with thyroid hormones is needed to im ... | 2011 | 22792746 | 
| spontaneous spinal epidural haematoma due to arteriovenous malformation in a child. | spontaneous spinal epidural haematoma (sseh) is a rare clinical entity, especially in infants, in whom only a few cases have been reported. in a paediatric emergency setting, sseh should be considered as part of the differential diagnosis for acute extremity weakness and paraesthesia. epidural vascular malformations are often suspected in these cases but have rarely been demonstrated. the authors report herein a case of sseh in a 9-year-old boy arising from an epidural vascular malformation. he  ... | 2011 | 22696725 | 
| paraneoplastic subacute sensory neuronopathy in association with adenocarcinoma of the prostate. | paraneoplastic syndromes arise infrequently in prostate cancer and paraneoplastic subacute sensory neuronopathy has not previously been reported in association with prostate cancer. when paraneoplastic syndromes occur, it is usually in the setting of small-cell carcinoma of the prostate or advanced, hormone-resistant disease. here the authors report a 64- year-old man who developed a progressive, severe, sensory neuronopathy in the setting of a recently diagnosed stage t4 hormone-responsive pros ... | 2011 | 22689835 | 
| "transferred to another institution": clinical histories of psychiatric patients murdered in the nazi "euthanasia" killing program. | this study aims to examine the practice of medical reporting in a totalitarian environment including systematic killing of people with mental illness in nazi germany. the historical analysis is based on patient documents and administrative files at today's district hospital, gunzburg, as well as on patient documents of inventory r 179 of the branch office of the federal archives (bundesarchiv) in berlin/lichterfelde. the paper describes four patient histories and attempts to reconstruct some asp ... | 2011 | 22572090 | 
| primary sjögren's syndrome or multiple sclerosis? our experience concerning the dilemma of clinically isolated syndrome. | the authors present the case of a 50 years old woman who during 3 years had a transient right limbs palsy, and numerous episodes of unilateral/bilateral optic neuropathy. the csf and mri examinations did not sustain the diagnosis of multiple sclerosis (ms). after 2 years from the onset, she presented bilateral trigeminal neuropathy, and after 9 months the anti-ss-a and anti ss-b antibodies were positive. the sialography and the minor salivary ducts biopsy (in the absence of xerostomia and xeroph ... | 2011 | 22568276 | 
| immediate intraocular pressure rise after intravitreal injection of ranibizumab and two doses of triamcinolone acetonide. | to evaluate prospectively immediate intraocular pressure (iop) changes after the intravitreal injection of ranibizumab, 2 and 4mg triamcinolone acetonide. | 2011 | 22553690 | 
| successful treatment of t4 renal cell carcinoma after a neoadjuvant targeted therapy using sunitinib: report of a case. | since the introduction of targeted therapy, treatment of metastatic renal cell carcinoma (rcc) has undergone dramatic changes. responses to targeted therapy within the primary tumor and metastatic lesions are novel findings not seen with immunotherapeutic-based strategies. we report here a case of t4 rcc in which cytoreductive nephrectomy became possible after a neoadjuvant targeted therapy using sunitinib. our experience with the present case suggests that targeted therapy in the neoadjuvant se ... | 2011 | 22531125 | 
| aggressive hemangioma of the thoracic spine. | vertebral hemangiomas are common lesions and usually considered benign. a rare subset of them, however, are characterized by extra-osseous extension, bone expansion, disturbance of blood flow, and occasionally compression fractures and thereby referred to as aggressive hemangiomas. we present a case of a 67-year-old woman with progressive paraplegia and an infiltrative mass of t4 vertebra causing mass effect on the spinal cord. multiple conventional imaging modalities were utilized to suggest th ... | 2011 | 22470764 | 
| combined transoral and suprahyoid approach for oropharyngeal cancers: an alternative to mandibulotomy. | surgical treatment of oropharyngeal tumours usually requires mandibular osteotomy. using this technique allows a better exposure and an easier excision, but this approach often generates complications. since 1995, we used a less aggressive surgical technique, with a suprahyoid pharyngotomy when the oral approach was not sufficient, thus sparing the mandible. | 2011 | 22416489 | 
| protection of penaeus monodon from infection of white spot syndrome virus by dna construct expressing long hairpin-rna against icp11 gene. | a plasmid construct (picp11-lh) was designed to constitutively express long-hairpin rna (lhrna) against icp11 gene, which is reportedly the most highly expressed gene of white spot syndrome virus (wssv) and likely to have an important role in viral pathogenesis. the construct was used singly and in combination with other similar constructs designed against vp28 and vp19. a total of 6 treatments, t1 (picp11-lh; 35 μg), t2 (pvp28-lh; 35 μg), t3 (pvp28-lh and pvp19-lh; 17.5 μg each), t4 (pvp28-lh a ... | 2011 | 23637487 | 
| high throughput fabrication of disposable nanofluidic lab-on-chip devices for single molecule studies. | an easy method is introduced allowing fast polydimethylsiloxane (pdms) replication of nanofluidic lab-on-chip devices using accurately fabricated molds featuring cross-sections down to 60 nm. a high quality master is obtained through proton beam writing and uv lithography. this master can be used more than 200 times to replicate nanofluidic devices capable of handling single dna molecules. this method allows to fabricate nanofluidic devices through simple pdms casting. the extensions of yoyo-1 s ... | 2012 | 23898358 | 
| spinal anaesthesia for caesarean section: plain vs hyperbaric bupivacaine. | to compare the clinical characteristics of sensory and motor block as well as haemodynamic stability using plain and hyperbaric bupivacaine in spinal anaesthesia for caesarean section. | 2012 | 23862255 | 
| the effect of n-3 long chain fatty acids supplementation on plasma peroxisome proliferator activated receptor gamma and thyroid hormones in obesity. | peroxisome proliferator-activated receptor gamma (ppar γ) is a transcription factor, which is abundantly expressed in adipose tissue and has a direct link to adiposity. it seems that long-chain polyunsaturated fatty acids (lc-pufas) can regulate ppar γ expression. the purpose of this study was to investigate the effects of n-3lc pufa supplementation on plasma levels of ppar γ and thyroid hormones in obesity. | 2012 | 23825994 | 
| strengthening socio-emotional competencies in a school setting: data from the pyramid project. | development of socio-emotional competencies is key to children's successful social interaction at home and at school. | 2012 | 23822531 | 
| [amyloid polyneuropathies--biochemical and genetic aspects]. | familial amyloid polyneuropathies (fap) are among the most frequent hereditary amyloidoses. these are serious, most often fatal diseases with autosomal dominant inheritance. fap can be caused by mutations in four genes, namely those encoding transthyretin, al-apoliprotein, gelsolin, and beta-2 microglobulin. transthyretin is a tetramer composed of four identical subunits linked by non covalent bonds and bearing binding sites for thyroxine (t4) and retinol-binding protein (rbp). more than 120 tra ... | 2012 | 23815016 | 
| effects of natural bioactive products on the growth and ginsenoside contents of panax ginseng cultured in an aeroponic system. | this study was conducted to evaluate the effects of natural bioactive products such as manda enzyme (t1), yangmyeongwon (t2), effective microorganisms (t3), and kelpak (t4) on the growth and ginsenoside contents of panax ginseng cultured in an aeroponic system using a two-layer vertical type of nutrient bath under natural light conditions. the growth of ginseng plants showed specific characteristics according to the positions in which they were cultured due to the difference of light transmittan ... | 2012 | 23717147 | 
| the effect of red ginseng extract on inflammatory cytokines after chemotherapy in children. | ginseng has been used as an herbal medicine, widely used in asian countries, for long time. recently, beneficial effects for immune functions of korean red ginseng (krg) have been reported in adults. this study was performed to investigate the effects of ginseng on immune functions in children after cessation of chemotherapy or stem cell transplantation for advanced cancer. thirty patients, who were diagnosed and treated for leukemia and solid cancer at the department of pediatrics and adolescen ... | 2012 | 23717140 |