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persistence of approach response after decerebration in newly hatched quail chicks.the role of telencephalon in controlling the unconditional approach response was studied in newly hatched japanese quail chicks by lesions. approach to flickering light and a moving object were not diminished by ablation of various telencephalic areas, ranging from caudal forebrain lesions to complete bilateral hemispherectomy. open field activity and tonic immobility were likewise unaffected. results indicated that the neural mediation of unconditional sensory-motor components of imprinting is ...19938511175
evidence that estrogen binding sites are present in bone cells and mediate medullary bone formation in japanese quail.studies were carried out in japanese quail to characterize the binding of estrogen to bone cells and to determine whether induction of medullary bone by estrogen is mediated by estrogen receptors. first, attempts were made to identify specific, high affinity nuclear binding sites for estrogen with a nuclear exchange assay in oviduct and femora from laying female quail and in liver, kidney, and femora from adult male quail treated with estradiol valerate (2 mg per bird). high-affinity nuclear est ...19938479958
stimulus control of copulatory behavior in male japanese quail.the copulatory behavior of sexually experienced male japanese quail was tested using taxidermic models with varying proportions of natural and artificial features. completely artificial models exerted little control over copulatory behavior, and whole natural body models reliably elicited copulatory behavior. in single model presentation tests, a model containing a natural head and neck with an artificial body was as effective in eliciting copulatory behavior as a whole body model, but a model c ...19938479957
neurofilament deficiency in quail caused by nonsense mutation in neurofilament-l gene.the existence of a neurofilament-deficient mutant of japanese quail was recently documented (yamasaki, h., c. itakura, and m. mizutani. 1991. acta neuropathol. 82:427-434), but the genetic events leading to the neurofilament deficiency have yet to be determined. our molecular biological analyses revealed that the expression of neurofilament-l (nf-l) gene was specifically repressed in neurons of this mutant. to search for mutation(s) responsible for the shutdown of this gene expression, we cloned ...19938468353
the catecholaminergic system of the quail brain: immunocytochemical studies of dopamine beta-hydroxylase and tyrosine hydroxylase.the distribution of dopamine beta-hydroxylase and tyrosine hydroxylase, two key enzymes in the biosynthesis of catecholamines, was investigated by immunocytochemistry in the brain of male and female japanese quail. cells or fibers showing dopamine beta-hydroxylase and tyrosine hydroxylase immunoreactivity were considered to be noradrenergic or adrenergic, while all structures showing only tyrosine hydroxylase immunoreactivity were tentatively considered to be dopaminergic. the major dopaminergic ...19938095939
developmental retardation of the japanese quail embryo under the influence of dexamethasone.cultured japanese quail embryos were treated with various doses of dexamethasone on day 2 and in part also on day 5. the treatment lead to a significant delay of development. this was demonstrated by means of developmental (growth rate, developmental stage), histological and metabolic (excreted uric acid, protein synthesis) parameters. the effect was intensified when the agent was administered into the subembryonic liquid instead of the albumen. this is due to the fact that a higher dilution is ...19938480074
subtelencephalic visual discrimination in selected lines of japanese quail.we studied visual discrimination capabilities of the avian brain stem in genetic lines of japanese quail artificially selected for unconditional approach preference for blue, red or an achromatic pattern stimulus. complete telencephalectomy did not abolish approach behavior and visual discrimination. our data indicate that visual feature extraction and motor coordination related to early approach preferences in birds may be mediated by brain stem and thalamic circuitries which do not require inp ...19938477047
celadon: an eggshell color mutation in japanese quail.a new eggshell color mutant was discovered in the japanese quail. this trait was named "celadon" and was shown to be controlled by an autosomal recessive gene. therefore, the gene symbol ce was proposed. this gene and an autosomal recessive gene we controlling a white eggshell trait were shown to be nonallelic. also, ce was shown to be hypostatic to we. a spectrophotometric analysis revealed that the celadon eggshell pigments are protoporphyrin and biliverdin as in the wild-type eggshell, but th ...20068228165
activity of ornithine decarboxylase in muscle of japanese quail in hypergravity conditions.ornithine decarboxylase (odc) is the rate limiting enzyme in the synthesis of polyamines which are generally required for animal cell proliferation. because of many different stimuli changing the activity of odc, the effect of hypergravity on muscle odc activity in japanese quail was investigated. adult japanese quail cockerels were exposed to 2g in the centrifuge permanently for 96 hours. the activity of odc was determined by radioisotopic method in supernatant of homogenised breast and fibular ...199311538516
amino-acid sequence of the alpha d- and beta-polypeptide chains of the japanese quail hemoglobin.two hemoglobin components are recognized in the erythrocytes of the adult japanese quail: a major (q-ii) and a minor (q-i) component. we have determined the amino-acid sequence of the alpha d-globin of the minor component and the beta-globin which is common to both components by conventional protein sequence analysis. the sequences of both the alpha d- and the beta-globins showed close homology with those of their counterpart constituents in other avian hemoglobins. proline at position 119 in th ...19938471178
effect of anabolic steroids on new fiber formation and fiber area during stretch-overload.the efficacy of anabolic steroid treatment to increase the extent of overload-induced new fiber formation and fiber hypertrophy was examined in anterior latissimus dorsi (ald) muscles of japanese quails. adult quails were assigned to a control group (n = 20), which received stretch but no steroid (ns), or a stretch+steroid group (s), which received either nandrolone decanoate (n = 20) or testosterone enanthate (n = 12). steroids were administered at 4.0 mg.kg body wt-1 x day-1. a weight correspo ...19938458803
activity of cholinesterases in the japanese quail embryo. effects of dichlorphos on the embryonic development.cholinesterase activity is detectable in the japanese quail embryo, in the yolk and subembryonic liquid, but not in the albumen. obviously, this enzyme is deposited by the hen into the yolk and from there it is transferred to the subembryonic liquid. in contrast, in the embryo the enzyme is synthesized by itself and the amount increases with the age of the embryo. by using bw284c51 1,5-bis-(4-allyldimethylammoniumphenyl)pentan-3-one bromide and iso-ompa tetraisoprophylpyrophosphoramide as inhibi ...19938424827
nitrogen excretion in japanese quail during protein depletion and repletion.the influence of protein depletion and repletion on the excretion of uric acid, urea, creatinine and free arginine as well as on the activities of xanthine dehydrogenase and arginase in japanese quail was studied. adult cockerels normally fed until the age of 42 days were kept on a protein free diet for 21 days and subsequently for 14 days on the previous normal diet. the control group was fed normal diet for the whole time. in 1-5 days intervals the enzyme activities and the n-metabolites in 24 ...19938585792
[a possible pathway for mitogenic signal transmission during the contact stimulation of the multiplication of cultured cells].cultured cells of the japanese quail embryo were labeled with 3h-glucosamine, fixed, suspended and inoculated into built-up cultures of the homologous cells. the transfer of insoluble components of labeled cell surface into the cells of underlaying cell sheet was revealed. a decrease in the cell incubation temperature up to 4 degrees c blocks the process. the exchange of cell surface sites between contacting cells seems to be one of the possible ways of information transmission from one cell int ...19938475579
immunoelectron microscopic detection of estrogen target cells in the bone marrow of estrogen-treated male japanese quail.the localization of estrogen receptors (ers) in bone marrow cells was studied immunoelectron microscopically in the femurs of estrogen-treated male japanese quail. the electron-dense reaction product showing er localization was not detected in the bone marrow cells of the male quail. after 48 h of estrogen treatment, nuclear reaction product was observed in many mononuclear cells in the bone marrow. most were located in the marrow stroma, and they were divided into undifferentiated and different ...19938453320
responses to isolation in japanese quail genetically selected for high or low sociality.the adrenocortical, behavioral, and leucocytic responses to isolation, for 1, 3, or 72 h, of 7-10-day-old japanese quail chicks, of lines selected for high (hsr) or low (lsr) levels of social reinstatement (sr) behavior, were studied. isolation had no effect on plasma corticosterone levels of heterophil/lymphocyte measures in lsr line chicks. conversely, circulating corticosterone levels were increased after 1 h of isolation in the hsr line, although they fell to control levels thereafter. heter ...19938434061
[forms of xanthine oxidoreductase in the tissues of japanese quail].the japanese quail tissues--liver, kidney and pancreas were analysed for the presence of forms of xanthine oxidoreductase utilised cofactors nad+, molecular oxygen or artificial acceptor--methylene blue, as well as for the validity of correlation between enzymatic activity and diet protein content. four groups of animals with the experimental diets, the formulae of which are given in tab. i, and control group with a commercial mash were fed for ten days. for enzyme preparation, the rough purific ...19938346616
spermatogenesis in birds.it is concluded that in the birds which have been studied there is a well-defined, regular cycle of the seminiferous epithelium, and that spermatogenesis involves synchronization of the activities of germ cells within and between successive generations to produce cellular associations of the seminiferous epithelium which are essentially similar to those described in mammals. however, the area of a cellular association is smaller in birds than in most (and probably all) mammals so that numerous c ...19938336978
beta,beta'-iminodipropionitrile toxicity in normal and congenitally neurofilament-deficient japanese quails.morphological effects of a neurotoxin, beta,beta'-iminodipropionitrile (idpn) were analyzed in normal and congenitally neurofilament (nf)-deficient japanese quails. these quails (6 weeks old) were injected intraperitoneally with idpn (0.2 g/kg body weight) three times every 3 days. they were necropsied at 10 to 12 days after the first injection. in normal quails, axonal swellings were observed histologically in the ventral motoneurons, ventral root, commissura grisea and spinal ganglion in the c ...19938310813
smaller number of large myelinated fibers and focal myelin thickening in mutant quails deficient in neurofilaments.the peripheral nervous system of a mutant of a japanese quail deficient in neurofilaments (mutant) and of a normal japanese quail (control) was morphometrically evaluated to characterize the morphological findings, especially those of the myelinated fibers of the mutant. in the proximal peroneal nerves, the frequency of the teased myelinated fibers showing the focal myelin thickening was higher in mutant than in control (p < 0.001) without obvious ongoing axonal degeneration and segmental demyel ...19938213082
experimental modification of vitellogenesis in japanese quail by trypan blue in vivo.ovaries of adult japanese quails were exposed in vivo to the acid bisazo dye trypan blue (tb) which binds to plasma albumin, the plasma precursor of the yolk protein alpha-livetin. by a combination of fluorescence microscopy and electron microscopy alpha-livetin could be localized in the subdroplets of intermediary and yellow yolk spheres. trypan blue alters vitellogenesis in the non-disc region of follicles in rapid growth in a reversible and dose-dependent way. less yolk is produced over 24 h ...19938142041
daily rhythm of plasma insulin in japanese quail (coturnix c. japonica) fed ad libitum.1. plasma levels of immuno-reactive insulin (iri) of 6 groups of 5-week-old quail, held on a 16l:8d photoregime, were measured every 4 hr, for 24 hr. 2. concentrations of plasma iri varied during the 24 hr period (anova, p < 0.003). insulin levels were high (mean = 857 pg/ml) from 6 a.m. (light onset) until 6 p.m. (4 hr before light offset) and low (mean = 185 pg/ml) at 10 p.m. and 2 a.m. 3. iri concentrations at 6 a.m., 10 a.m., 2 p.m. and 6 p.m. were significantly different from values at 2 a. ...19938094654
photoperiodic induction in vitro: the dynamics of gonadotropin-releasing hormone release from hypothalamic explants of the japanese quail.the japanese quail is a photoperiodic animal that under certain experimental conditions can respond to a single long day with a wave of lh secretion. such a system offers an opportunity to analyze the photoneuroendocrine changes as they occur in real time, especially as all of the neural machinery (photoreceptor, clock, and gnrh system) is believed to lie within the hypothalamus. the first detectable rise in lh occurs at about hour 23 of the long day, and this single inductive event leads to pro ...19921446626
subchronic toxicity and reproduction effects of tri-n-butyltin oxide in japanese quail.a subchronic toxicity/reproduction study was performed in japanese quails that were fed a diet containing 0, 24, 60, and 150 mg tri-n-butyltin oxide (tbto) per kg basal diet for 6 weeks. eggs produced during the 6 weeks of treatment were incubated and hatched, and chicks hatched from eggs collected in weeks 5 and 6 of exposure were reared for 2 weeks. in parent quail, neither diminished food consumption nor any overt toxic or histopathologic signs were observed following exposure to tbto. a stat ...19921444589
a histochemical study of acid phosphatases in medullary bone matrix and osteoclasts in laying japanese quail.acid phosphatase activity in medullary bone matrix and osteoclasts of laying japanese quail was examined histochemically. to avoid nonspecific staining, the reactivity of the enzyme was evaluated using both the azo dye method and the lead salt method and nonembedded thick sections and resin-embedded thin sections. the ph of the incubation medium was also varied from the acid range (ph 5.0 and 6.5) to the alkaline range (ph 8.5). medullary bone osteoclasts contain both tartrate-resistant acid pho ...19921281604
proliferative responses of quail aortic smooth muscle cells to benzo[a]pyrene: implications in pah-induced atherogenesis.repeated exposure of avian and rodent species to benzo(a)pyrene (bap) has been associated with the development of aortic lesions of atherosclerotic etiology. because the occurrence of these lesions may involve alterations in the regulation of smooth muscle cell (smc) growth, the present studies were conducted to evaluate the proliferative responses of quail aortic smcs to bap treatment in vivo and in vitro. measurements of [3h]thymidine incorporation and cell growth were conducted in cultured ao ...19921519246
research note: eggshell quality in japanese quail fed different fatty acids.the purpose of the present study was to determine the effects of diets containing 3% palmitic acid (diet pa), oleic acid (diet oa), or linoleic acid (diet la) on the shell quality of eggs of japanese quail. each diet was fed to 10 hens maintained individually in wire quail laying cages. there was no difference (p greater than .05) in feed consumption between hens fed diets oa and la, but hens of both groups consumed less (p less than .05) feed than those fed diet pa. egg weight, shell weight, an ...19921409241
fear and distress in japanese quail chicks of two lines genetically selected for low or high adrenocortical response to immobilization stress.behavioral and adrenocortical reactivity to stressful stimulation was examined in 12- and 13-day-old chicks of two lines of japanese quail selected over several generations for exaggerated (hs: high stress) or reduced (ls: low stress) plasma corticosterone (b) response to brief immobilization stress. plasma b concentrations and tonic immobility (ti) fear reactions were measured in unstressed (control) and stressed (overnight cooping) chicks of both lines. the stress treatment was applied over a ...19921398557
increased responding to female stimuli as a result of sexual experience: tests of mechanisms of learning.sexual experience increases the response of males to stimuli provided by female conspecifics in a variety of species. the mechanisms of learning involved in this type of phenomenon were explored in two experiments with japanese quail. the results indicated that instrumental conditioning with copulatory opportunity is not necessary for the acquisition of responding to female cues, and responding is not facilitated by learning about the location of the female. however, the response of males to fem ...19921455010
smooth muscle cells in the walls of ovarian follicles in the japanese quail.the walls of pre-ovulatory follicles of the japanese quail were examined at the ultrastructural level for the presence of cells displaying the typical morphological features of smooth muscle cells. these characteristics were found in the cells of the chordae, the tunica albuginea, and the theca externa. small, elongated cells, containing microfilaments, were observed in the theca of prelampbrush follicles localized in the ovarian cortex. these thecal cells were considered as the putative precurs ...19921423484
behavioral demasculinization of female quail is induced by estrogens: studies with the new aromatase inhibitor, r76713.the injection before day 12 of incubation of estradiol benzoate (eb) into japanese quail eggs produces a complete behavioral demasculinization of adult males that will hatch from these eggs. these males never show copulatory behavior even after administration of high levels of exogenous testosterone (t). it is usually assumed that such a demasculinization normally takes place in female embryos under the influence of endogenous estrogens but few experimental data are available to confirm the vali ...19921612564
effect of dietary aflatoxin b1 on the growth response and haematologic changes of young japanese quail.feeding of aflatoxin b1 at the rate of 0.5 ppm to young japanese quail resulted in significant (p less than 0.01) decrease in body weight gain that became apparent on the third week. there was no significant difference in the mean values of haemoglobin, packed cell volume and total erythrocyte counts of quail chicks given aflatoxin b1 in feed in comparison to those fed on a similar diet without aflatoxin. however, the total leucocyte count revealed an increase on the third week which was due to ...19921528228
the influence of dietary protein on carcass composition and sexual maturity in a randombred population of japanese quail (r1) and a subline of r1 selected for increased body weight.1. selection for body weight in japanese quail has altered the protein requirements for growth and reproductive development in the selected line and randombred control population from which it was developed. 2. in both the selected and randombred lines, the protein requirement for growth is different from that for maximal reproductive development.19921354586
the hypotrophic axonopathy mutant in japanese quail.a new behavioral mutant showing either head or body quivering, or both, was found in japanese quail. this trait was characterized by neurofilament deficiency in the axons of the cervical spinal cord and the optic and sciatic nerves and was named "hypotrophic axonopathy." this character was shown to be controlled by an autosomal recessive gene, for which the gene symbol hax was proposed.20031624771
research note: antioxidant activity of japanese quail liver cytosol in the absence and presence of reduced glutathione.the antioxidant activity of japanese quail liver cytosol was assessed in the presence of .1, 1.0, or 10.0 mm reduced glutathione (gsh) using an in vitro assay system that utilized quail liver microsomes as the lipid substrate. the formation of malonaldehyde (ma), an indicator of lipid peroxidation, was reduced (p less than .01) by 1.0 and 10.0 mm gsh, even in the absence of cytosolic protein. cytosolic protein at a level of 1 mg/ml of assay medium did not further reduce ma formation at any of th ...19921608887
[the effect of fatty acids in the feed on xanthine dehydrogenase activity in the japanese quail].the aim of the present study is to determine the effect of different fatty acids on the amino acid catabolism judged on the level of xanthine dehydrogenase (xdh). the model system of protein depletion with subsequent repletion was used in the trial consisted of japanese quails 71 days old. in the period of protein repletion, the fatty acid (stearic, palmitic, oleic, linolenic, linoleic and lauric, respectively) was used instead of common fatty compound in the diet. specific activities of xdh in ...20161413394
interactions of plant zinc and plant species on the bioavailability of plant cadmium to japanese quail fed lettuce and spinach.many cadmium-contaminated environments contain high levels of zinc. the effects of plant zn and plant species on plant cd bioavailability were tested in japanese quail fed lettuce and spinach. four groups of birds received 10% of their diets as lettuce or spinach leaves intrinsically labeled with 109cd and containing low or high intrinsic zn. two other groups were fed control diets containing 109cd as cdso4 and low or high zn as znco3. cadmium concentrations in diets ranged from 0.857 to 1.05 mi ...19921740097
influence of cadmium on polychlorobiphenyl uptake, mfo activity, and serum lipid levels in japanese quail.the effect of cadmium on the metabolism of polychlorobiphenyls (pcbs) (aroclor 1260) was investigated in quails fed diets containing 100 ppm cd, 100 ppm pcbs (aroclor 1260) and 100 ppm cd + 100 ppm pcbs for a period of 45 days. the presence of cd in the diet did not interfere with mfo activity (erod and alde) and cytochrome p-450 enzymes. quails fed simultaneously with cd and pcbs, accumulated pcbs in muscle five times greater than quails fed pcbs only. quails fed with cd-containing diet showed ...19921536603
a comparison of genetic variability in strains of japanese quail selected for heavy body weight.electrophoretic analyses of body tissues from three strains of japanese quail from the quail genetic stock centre at the university of british columbia, two selected for heavy body weight and one randombred, were carried out to determine whether genetic variations in selected strains were different from randombred strains. in addition, the data were also compared with those obtained from domestic and wild populations in japan. the proportion of polymorphic loci was higher in the heavy strains th ...20081552157
distribution of benzodiazepine binding sites in the brain of the male japanese quail and its correlation to a hormonal control: quantitative autoradiography study.quantitative receptor autoradiography was used to study the neuroanatomical distribution and effects of gonadal hormones on [3h] flunitrazepam binding in the male japanese quail brain. in gonadally intact quail brains, [3h] flunitrazepam displayed a heterogeneous distribution, with elevated levels in the posterior brain regions such as the stratum griseum et fibrosum superficiale and stratum griseum centrale of the optic tectum. lower values were observed in the anteriorly located brain sites su ...19921319005
effects of castration and testosterone treatment on the development and involution of the bursa of fabricius and the thymus in the japanese quail.we investigated the effects of castration on the development of lymphoid organs (bursa of fabricius, thymus, and spleen) in the japanese quail during 4-8 weeks of age under a long photoperiod (16l:8d) and the effect of testosterone implantation on the involution of the lymphoid organs under long (16l:8d) and short (8l:16d) photoperiods. under 16l:8d, the bursa of fabricius and thymus in intact quail grew rapidly and reached a peak at 6 weeks of age and regressed thereafter. in contrast, developm ...19911808023
variability of c-banding patterns in japanese quail chromosomes.observations were made of the c-banding patterns in several cells from 182 japanese quail embryos to detect presence of stable variants. each of the eight largest autosomes contains a c-band at the centromeric region. the short arm of autosome 8 is c-band positive, as is the entire w chromosome. the z chromosome consistently contains an interstitial c-band in the long arm and a less prominent one in the short arm. distinct variants of chromosome 4 and the z chromosome were observed. in the z chr ...19911778471
testosterone effects on staining density and autoradiographic investigations of the alpha 2-adrenergic receptor in the medial preoptic nucleus of the japanese quail: relationship to the activation of reproductive behavior.the effects of gonadectomy combined or not with testosterone (t) therapy on the sexual behavior, cloacal gland area, staining density and alpha 2-adrenergic receptors in the medial preoptic nucleus (pom) were studied in male and female japanese quail. in castrated males, t increased the cloacal gland size and activated copulatory behavior. in agreement with previous reports, these effects were sexually differentiated: under the influence of t, cloacal gland growth was smaller and this treatment ...19911725736
body, abdominal fat, and testes weights, and line by sex interactions in japanese quail divergently selected for plasma cholesterol response to adrenocorticotropin.line by sex interactions of bw, abdominal fat, testes weight, and plasma cholesterol were investigated in two japanese quail lines. high (h-pchol) and low (l-pchol) quail lines had been developed by 18 generations of divergent selection for plasma cholesterol response to adrenocorticotropin (acth). quail were from generation 28 breeders maintained under a normal environment with no exposure to exogenous acth after generation 18. quail from growth-selected lines were also used to examine relation ...19911664517
research note: lack of an effect of high levels of menadione on tumor development in japanese quail females.the objective of the experiment was to study the influence of a high but nontoxic dietary level of menadione (vitamin k3) on the incidence of leiomyomas and leiomyosarcomas in the oviduct of females from various lines of japanese quail. analyzed values of vitamin k3 per 1,000 kg of feed were 7.37 g in the control diet, and 149.6, 1,722, and 3,722 g for the experimental diets from 0 to 4, 5 to 8, and after 8 wk of age, respectively. females were killed after they had been in production for 158 da ...19911754553
effects of antiestrogenic compounds on avian medullary bone formation.administration of estradiol to male japanese quail induced the formation of medullary bone in the marrow cavities of the bird's femora and tibiae. this was accompanied by increased serum levels of calcium, phosphorus, and alkaline phosphatase activity. we examined the effects of two structurally distinct "antiestrogens" on the estrogen-induced formation of medullary bone in this quail model. trioxifene (ly133314) and tamoxifen are members of a group of compounds commonly referred to as antiestro ...19911805547
retinally perceived light can entrain the pineal melatonin rhythm in japanese quail.the avian pineal organ contains a circadian oscillator that can drive a daily rhythm of melatonin synthesis. in some avian species the pineal organ may act, via the cyclic release of melatonin, as a pacemaker within a multioscillator circadian system. the routes by which light entrains the pineal melatonin rhythm were investigated in the japanese quail. a 'patching' protocol was used to expose directly either the eyes or the pineal to a light-dark cycle while the rest of the bird was exposed to ...19911786552
effects of in ovo estradiol benzoate treatments on sexual behavior and size of neurons in the sexually dimorphic medial preoptic nucleus of japanese quail.in male japanese quail, the injection of estradiol benzoate (eb) in the egg causes a complete loss of the testosterone (t)-induced copulatory behavior (behavioral demasculinization). this treatment is only effective if performed before day 12 of incubation. this suggests that embryonic estrogens affect in a permanent way brain structures controlling sexual behavior. the medial preoptic nucleus (pom) is the only sexually dimorphic brain nucleus identified in quail and it is a key center for the a ...19911756391
genetic polymorphism of erythrocyte histone h1 in japanese quail.histone h1 from erythrocytes of japanese quail was resolved in a sodium dodecyl sulfate (sds)-polyacrylamide gel into five fractions differing in apparent molecular weights. a polymorphism of histone h1.1, h1.2, and h1.3 bands was detected among quail individuals. while some birds possessed either a high (phenotype .3+) or a low (phenotype .3+/.3-) level of h1.3, at least half of the quail population lacked this h1 band (phenotype .3-). appropriate genetic crosses demonstrated that h1.3 behaved ...19911772400
refined x-ray crystal structures of the reactive site modified ovomucoid inhibitor third domains from silver pheasant (omsvp3*) and from japanese quail (omjpq3*).tetragonal and triclinic crystals of two ovomucoid inhibitor third domains from silver pheasant and japanese quail, modified at their reactive site bonds met18-glu19 (omsvp3*) and lys18-asp19 (omjpq3*), respectively, were obtained. their molecular and crystal structures were solved using x-ray data to 2.5 a and 1.55 a by means of patterson search methods using truncated models of the intact (virgin) inhibitors as search models. both structures were crystallographically refined to r-values of 0.1 ...19911870129
genetic and phenotypic relationships in japanese quail. 1. body weight, carcass, and organ measurements.live bw, carcass data, and organ data taken at 34 days of age on approximately 1,000 quail of both sexes from 110 sires and 290 dams were utilized to estimate genetic parameters from the initial generation of a selection study. the birds represented a sample of a line selected for high 4-wk bw. data were analyzed using henderson's method 3 (mm3) and restricted maximum likelihood (reml) with and without a relationship matrix. the paternal half-sib heritabilities for body, carcass, and organ weigh ...19911924086
estrogen target cells during the early stage of medullary bone osteogenesis: immunohistochemical detection of estrogen receptors in osteogenic cells of estrogen-treated male japanese quail.the localization of estrogen receptors (er) in osteogenic cells during the early stage of medullary bone osteogenesis was studied immunohistochemically in the femurs of estrogen-treated male japanese quail. alkaline phosphatase (alp) activity was used as a marker for osteogenic cells. er immunostaining was observed in the nuclei of weak alp-positive bone lining cells on the endosteal bone surface of nontreated birds. after 24 hours of estrogen treatment, nuclear immunostaining was detected in al ...19911913292
effects of selection for growth and selection diet on eggshell quality and embryonic development in japanese quail.decreased hatchability in japanese quail following selection for growth and relative improvements in hatchability following selection during goitrogen treatment were investigated. an unselected quail line (line c) and lines selected for high 4-wk body weight while being fed diets containing either 20% cp and .2% thiouracil (tu) (line t), or 28% cp and no tu (lines p and h-cd) were used. egg weight loss between 0 and 4, and 0 and 14 days of incubation, hatchability, and developmental stage of emb ...19911886856
plasma melatonin levels in japanese quail exposed to dim light are determined by subjective interpretation of day and night, not light intensity.plasma melatonin levels were measured in male japanese quail exposed to lighting schedules consisting of combinations of bright light (2000 or 1500 lx), darkness, or dim light (2 lx) or to constant dim light. melatonin levels in dim light were dependent upon the relative intensity of accompanying phases, being significantly higher when dim light was subjective night than when it was subjective day. there was no significant melatonin rhythm in constant dim light, even on the first day of constant ...19911879654
divergent selection for growth in japanese quail under split and complete nutritional environments. 5. feed intake and efficiency patterns following nineteen generations of selection.high (h) and low (l) quail lines divergently selected for 4-wk bw under complete-diet (cd) and split-diet (sd) environments were evaluated to examine changes in feed intake and feed efficiency before and after the age at selection. progeny from the four quail lines (h-sd, l-sd, h-cd, l-cd) were fed the cd in generation 17 and the sd in generation 19. the bw of h-line quail were highest under their respective selection environments, and the bw of quail in the l lines were highest under reciprocal ...19911852682
[ultrastructural and immunohistochemical study of experimental atherosclerosis in japanese quails].a marked plaque was produced at the tunica intima of the ascending aorta in all of the japanese quails of 9 weeks old which fed on atherogenic diet containing 2% cholesterol for 8 weeks, while no structural changes of aortic wall were observed in japanese quails which fed on normal basic food for the same period. the media of aorta in normal quails consist of smooth muscle cells, myofibroblast-like cells (mf) cells), and many successive elastic membranes. at the atherosclerotic lesion, many mf c ...19912044665
nocturnal hypothermia in fasting japanese quail: the effect of ambient temperature.japanese quail were equipped with intraperitoneal transmitters for telemetric measurement of body temperature (tb) and activity. food deprivation at + 24 degrees c for four days induced a well-defined nocturnal hypothermic response. the normal day-night difference (about 1 degrees c) in tb increased 1 degrees c per day, reaching 5 degrees c on the fourth night of fast. nocturnal motor activity decreased during the fast, while daytime activity first increased and then returned to the original lev ...19912062935
divergent selection for growth in japanese quail under split and complete nutritional environments. 4. genetic and correlated responses from generations 12 to 20.divergent selection during generations 12 to 20 for high (h) and low (l) 4-wk bw under split-(sd) and complete-(cd) diet environments resulted in continued progress in both upward and downward directions. following 20 generations of selection, there were 4.8- and 3.6-fold differences between bw of h and l lines in the sd and cd environments, respectively. regression coefficients of mean 4-wk bw on generation of 1.88 and 1.58 g in the h lines and -1.50 and -1.37 g in the l lines indicated symmetr ...19912047338
neuroanatomical specificity in the co-localization of aromatase and estrogen receptors.the relative distributions of aromatase and of estrogen receptors were studied in the brain of the japanese quail by a double-label immunocytochemical technique. aromatase immunoreactive cells (aro-ir) were found in the medial preoptic nucleus, in the septal region, and in a large cell cluster extending from the dorso-lateral aspect of the ventromedial nucleus of the hypothalamus to the tuber at the level of the nucleus inferioris hypothalami. immunoreactive estrogen receptors (er) were also fou ...19912030339
perpetuation of muscle fibers after removal of stretch in the japanese quail.stretch-overload has been shown to increase muscle mass in the anterior latissimus dorsi (ald) of the adult quail by increasing both fiber size and number, but it is not known whether the new muscle fibers or fiber size is maintained after removal of the stretch stimulus. a weight was added to the right wing of 40 adult quail while the left wing in each bird served as an intra-animal control. the weight was removed after 30 days of stretch, and terminal experiments were conducted 0, 30, 60, or 9 ...19912003569
plasma and yolk cholesterol levels in japanese quail divergently selected for plasma cholesterol response to adrenocorticotropin.studies were conducted to determine the effect of divergent selection for plasma cholesterol response to adrenocorticotropin (acth) on the levels and relationships between plasma and yolk cholesterol in japanese quail. cholesterol data were obtained in generation 25, following seven generations of relaxed selection, from birds maintained under a normal environment with no exposure to exogenous acth. levels of plasma and yolk cholesterol were determined at 22 and 28 wk. plasma cholesterol levels ...19911646444
embryonic development of japanese quail under microgravity conditions. 19912047468
the effect of the different gravity on the muscle composition in japanese quail. 19912047410
an endocrine response to short-term hypodynamy in japanese quail selected for resistance to hypodynamy. 19912047409
structural and biochemical effects in lungs of japanese quail following a 1-week exposure to ozone.the effect of ozone inhalation on birds was investigated. japanese quail were exposed continuously to 0, 0.3, 1.0, and 3.0 mg/m3 ozone (0, 0.15, 0.50, and 1.50 ppm, respectively) for 7 days. pulmonary effects were determined by light and electron microscopy as well as by biochemistry. focal areas of hemorrhages were noticed in the birds exposed to 1.0 mg/m3 ozone. additional effects after exposure to 1 mg/m3 included loss of cilia in trachea and bronchi, an inflammatory response, and necrosis of ...19912004636
effects of testosterone on a selected neuronal population within the preoptic sexually dimorphic nucleus of the japanese quail.the effects of testosterone on the volume and cytoarchitecture of the sexually dimorphic nucleus of the preoptic area (pom) were investigated in male and female japanese quail. it was confirmed that castration decreases the pom volume in males and that, in gonadectomized birds of both sexes, testosterone increases this volume to values similar to those observed in intact sexually mature males. this suggests that the sex difference in pom volume results from a differential activation by t so that ...19912007660
structural and immunohistochemical aspects of the postovulatory follicle in japanese quail.in the present study, we searched for the presence of granulosa lipid spheres, of lacunae, and of the smooth-muscle markers desmin and alpha-smooth-muscle actin, in the wall of the pof1 of the quail ovary. lacunae, using the labelled yolk technique, were visible as large cavities in the pof1 wall. the immunohistochemical localization of desmin was similar to that observed in preovulatory follicles. a similar distribution was observed using an anti-alpha-smooth-muscle actin antiserum, but the cel ...19911996782
testosterone metabolism in the avian hypothalamus.many central actions of testosterone (t) require the transformation of t into several metabolites including 5 alpha-dihydrotestosterone (5 alpha-dht) and estradiol (e2). in birds as in mammals, 5 alpha-dht and e2, alone or in combination, mimic most behavioral effects of t. the avian brain is, in addition, able to transform t into 5 beta-dht, a metabolite which seems to be devoid of any behavioral or physiological effects, at least in the context of reproduction. by in vitro product-formation as ...19911958558
immunoelectron microscopic demonstration of estrogen receptors in osteogenic cells of japanese quail.the localization of estrogen receptors (ers) in osteogenic cells was immunoelectron microscopically examined in the femurs of female and estrogen-treated male japanese quail. an electron dense reaction product showing er localization was observed in the nuclei of osteoblasts and immature osteocytes in the medullary bone of the female quail. however, reaction product was not seen in the osteoclasts. on the endosteal bone surface of male quail, nuclear reaction product was detected in bone lining ...19911938479
genetic factors accountable for line-specific dna fingerprint bands in quail.dna fingerprints, prepared from mixes of dna of individuals sampled from lines of japanese quail selected for high or low 4-week body weight, were used to evaluate the relative contribution of several evolutionary forces to genetic diversity among populations. comparisons between lines--two replicates of each selection direction and a control unselected line--were used to determine the frequency of line-specific dna fingerprint bands produced by each of three major evolutionary forces: 1) mutati ...19911831158
changes in organ growth pattern associated with long-term selection for high growth rate in quail.data are presented on the pattern of organ growth in embryos from a line of japanese quail selected for high growth rate and compared with those from a non-selected control line. the data reveal that the increased growth rate post hatching is accompanied by a more rapid early development of the digestive organs. it appears from these results that the "genes for" growth rate are the "genes for" early growth of the digestive organs.19911813440
hereditary hypotrophic axonopathy with neurofilament deficiency in a mutant strain of the japanese quail.a primary axonal disease affecting the central and peripheral nervous system was discovered in a new mutant strain of the japanese quail, named quiver (quv). quv showed significantly smaller cross-sectional areas of the cervical spinal cord and the optic and sciatic nerves, when compared with controls by light microscopic morphometry. in the cervical spinal cord, electron microscopic morphometry indicated that myelinated axons in quv were significantly smaller in size than in controls, though gr ...19911785256
influence of hypergravity on the ph profile and proteolytic activity of the avian gastrointestinal tract.the present study deals with the effect of hypergravity (2xg) on the ph and on the proteolytic activity in the digesta of the gastrointestinal tract of japanese quails during intense growth. the birds were raised on a semisynthetic diet containing free amino acids (a) and a commercial diet (b). during days 35 till 40 post-hatching the quails were exposed to hypergravity (2xg) using a specially designed centrifuge. on days 40 (experimental group, 2xg) and 41 (control group, 1xg) the animals were ...19911751480
a sex-dependent influence of testosterone on the dorso-medial neuronal population of the japanese quail intercollicular nucleus.the nucleus intercollicularis in quail is implicated in the control of a number of vocalizations. it is also a target structure for steroids and includes high numbers of cells containing androgen and estrogen receptors. we recently demonstrated that in another steroid target, the medial preoptic nucleus, the effects of testosterone are paralleled by significant changes in the neuronal size. a morphometrical analysis of the nucleus intercollicularis was therefore undertaken in male and female jap ...19911666401
gonadal regulation of gabaa receptors in the different brain areas of the male japanese quail.quantitative autoradiography was used to investigate the distribution and effects of gonadal hormones on [3h] muscimol (specific gabaa receptor ligand) binding in the male japanese quail brain. in gonadally intact japanese quail brains, [3h] muscimol revealed a heterogeneous distribution with high gabaa receptor levels in the cerebellum pars granularis (656 fmol/mg wet weight of tissue) and in the pars molecularis (405 fmol/mg wet weight of tissue). low receptor levels were found in the nucleus ...19911664340
structural difference of chymotrypsinogens forming chymotrypsin variants in japanese quail.a chymotrypsinogen showing the phenotype aa of chymotrypsin was purified from quail pancreas, and its chromatographic behavior, molecular weight, and electrophoretic mobility were very similar to those of another chymotrypsinogen, showing the aa phenotype of chymotrypsin. however, after activation, this chymotrypsinogen from aa showed band 5 of chymotrypsin, while the other chymotrypsinogen from aa did not. peptide mapping demonstrated that the molecular structures of the two chymotrypsinogens a ...19902085308
myosin isozyme expression in response to stretch-induced hypertrophy in the japanese quail.when skeletal muscle is subjected to stretch it undergoes a rapid increase in muscle mass. however, the effect of stretch on the native myosin isozyme content of muscle has received attention only recently. using the japanese quail to investigate stretch-induced hypertrophy, we demonstrated an increase in the expression of fast myosin in the predominantly slow anterior latissimus dorsi muscle (ald). the fast myosin content of the control quail ald is not sufficient to be quantified on native myo ...19902260780
androgen and estrogen action in the preoptic area and activation of copulatory behavior in quail.the sites of androgen and estrogen action on sexual behavior were studied in the preoptic area of castrated male japanese quail by stereotaxic implantation of hormones, antihormones and metabolism inhibitors. the first experiment demonstrated that bilateral implantation of the aromatase inhibitor, androstatrienedione (atd), in the sexually dimorphic nucleus (pom) of the preoptic area can completely suppress the behavioral activation produced by a systemic treatment with testosterone. the effects ...19902082358
effect of snake venom of agkistrodon halys on atherosclerosis and blood characteristics in japanese quail.extracts of snake venom have been widely used for the treatment of vascular thrombotic diseases, yet the therapeutic mechanism is not clear. the effect of snake venom fractions on atherosclerosis in japanese quail was studied. the venom of agkistrodon halys was fractionated by deae-cellulose chromatography and the pooled protein fractions that resulted were injected intravenously into the quail with aortic atherosclerosis induced by dietary cholesterol. after 7 weeks of injections on every other ...19902282093
the sequence of japanese quail ovalbumin cdna. 19902216734
a checkerboard pattern manifested by the oviduct epithelium of the japanese quail.the oviduct epithelium of the japanese quail is a monolayered epithelium consisting of two types of columnar cells, goblet type gland (g-) cells and ciliated (c-) cells. we found these cells to be arranged in a checkerboard pattern. three types of cell boundaries formed between the two different types of cells were examined statistically at various levels of the columnar cells. there was a tendency on the part of the cells to form boundaries between g- and c- cells rather than between two c- cel ...19901702680
head skeletal abnormalities associated with the throat tuft mutation (hfdtt) in the japanese quail.hereditary abnormalities of head skeleton ascribed to embryonic visceral arch defects were investigated in japanese quail homozygous for the throat tuft mutation (hfdtt). differential staining for bone and cartilage of 15-day embryos revealed partial deletion or irregularity in the mandible, basiparasphenoid, hyoid apparatus, and quadratojugal bones, incidences of which were 84, 44, 40, and 18%, respectively. incidence of the head-skeleton abnormality was 88% when individuals having at least one ...19902235840
diagnostic exercise: wasting syndrome in a flock of japanese quail. 19902166871
muscle fiber formation and fiber hypertrophy during the onset of stretch-overload.the contributions of fiber hypertrophy and new fiber formation to the onset of stretch-induced muscle enlargement were evaluated in the anterior latissimus dorsi (ald) of adult japanese quails, because it was not known whether the mechanisms which initiate new fiber formation were dependent on first achieving significant fiber hypertrophy. a weight corresponding to 10% of the bird's body mass was attached to one wing, and eight birds were killed after each day during the first week of stretch. m ...19902142581
biopotency of methionine sources and their effects on sexual maturity of growing japanese quail.1. japanese quail were fed on practical diets supplemented with graded amounts of dl-methionine (dl-m), dl-methionine-sodium (dl-m-na), dl-methionine hydroxy-analogue calcium (dl-mha-ca) and dl-methionine hydroxy-analogue free acid (dl-mha-fa) on an equimolar basis. 2. by the slope ratio assay using quail growth as the criterion, it was deduced that the biological activity of dl-m-na, dl-mha-ca and dl-mha-fa was approximately 0.96, 0.72 and 0.84 that of dl-m on an equimolar basis. 3. on a weight ...19902372708
[histological and histochemical changes in the neck muscles of spontaneously occurring scoliosis in a special strain of japanese quail, sqohm].a strain of japanese quail, sqohm, is known as a model of idiopathic scoliosis in humans. it shows hereditary scoliotic deformities occurring in the cervical region. histological, histochemical and serological studies were performed in 51 scoliotic and 109 non-scoliotic quail. histological study revealed internal nuclei and tiny groups of small fibers in the neck muscles. the incidence of these, however, was only 19% in the scoliotic and 7% in the non-scoliotic quail. histochemical observation w ...19901696302
protein requirement and amino acid imbalance in quail.1. growing japanese quail were fed on purified diets based either on dried egg albumen or casein supplemented with methionine. 2. at low protein concentration body mass, n-intake and n-growth requirement of chicks fed on diets containing casein were impaired compared to those fed on diets with egg albumen: in contrast at higher protein concentrations performance was better among those fed on diets with casein. 3. increased protein requirement was observed among birds fed on diets containing case ...19902354370
the effect of the angular velocity on the muscle composition in japanese quail. 19902371359
the effects of hypergravitation, hypodynamy and their combination on the quantitative ultrastructure of the heart muscle of japanese quail. 19902371321
accumulation and distribution of ions of group-iiia elements in the tissues and eggs of the japanese quail.solutions of salts of the five group-iiia elements were given, intravenously, to mature japanese quail. by 18 h, the accumulation maxima in the major tissues were: leg bones, 20% for ga+3 (67ga label) in estradiol-treated males; liver, 51% for al+3 (26al label) in control males; kidneys, 32% for in+3 (114min label) in estradiol-treated males; and growing oocytes plus ova, 37% for in. accumulations of tl+1 (202tl label) were 6 times those for ga or in in the brain and muscles, and .1 times in pla ...19902330333
[the subacute and subchronic toxicity of chlorophacinone in japanese quail (coturnix c. japonica)].accordingly to the subacute toxicity of chlorphacinone to japanese quail (lc 50: 60 mg/kg feed), the uptake of delicia-chlorphacinone-baits for several days can be lethal to birds as a matter of principle. a subchronic study resulted in a "no-observed-effect-level" of 1 mg chlorphacinon/kg feed. reproduction is not affected until dose levels which resulted in lethality or are accompanied by physiological changes (coagulability of blood, microcytic anaemia). increased sensibility of descendants t ...19902241472
melatonin does not link the eyes to the rest of the circadian system in quail: a neural pathway is involved.blinding by enucleation has a dramatic effect on the circadian activity rhythm of japanese quail. the activity patterns of enucleated birds held under 24-hr light-dark cycles are disrupted, although entrainment can persist in many birds. in constant darkness (dd), blinded birds are rendered arrhythmic. these results demonstrate that the eyes are a major component of the circadian system, and that insofar as enucleation produces arrhythmicity in dd, the eyes' role is not merely a photosensory one ...19902133141
the quail's eye: a biological clock.the site (intraocular vs. extraocular) of the biological clock driving a rhythm in melatonin content in the eyes of japanese quail was investigated by alternately patching the left and right eyes of individual birds, otherwise held in constant light, for 12-hr periods. this patching protocol, therefore, exposed each eye to a light-dark cycle (ld 12:12) 180 degrees (12 hr) out of phase with the ld cycle experienced by the other eye. the optic nerves to both eyes were transected prior to initiatin ...19902133136
toxicological and biological studies on japanese quails fed graded levels of furazolidone.furazolidone (fz) was administered to 42-day-old female japanese quails as a feed additive at doses of 0, 200, 400, 600 and 800 ppm for a period of 28 days. dose-dependent effects were observed. high levels of fz (600 and 800 ppm) significantly altered growth, decreased feed consumption, caused marked atrophy of the ovaries and oviducts leading to cessation of egg laying, and resulted in higher mortality. hepatotoxicity was evidenced by an increase in serum aspartate aminotransferase (ast), alan ...19902099613
influence of selection for increased body weight on the incidence of leiomyomas and leiomyosarcomas in japanese quail.leiomyomas and leiomyosarcomas were observed in adult laying hens from lines of japanese quail selected solely (hw) or partly (hw-hp; hw-lp) for increased 4-wk bw and the corresponding randombred control (r1). no neoplasms were observed in a line (lw) selected for decreased 4-wk bw based on observations in one generation. line r1 served as the base population for lines hw and lw and was maintained without conscious selection for any trait, lines hw-hp and hw-lp were sublines of line hw in which ...19892608612
[the characteristics of the morphofunctional organization of the lampbrush chromosomes from the oocytes of the rock dove].nuclei and chromosomes isolated from growing oocytes of the pigeon c. livia have been studied by light microscope techniques. the pigeon chromosomes in diplotene assume a lampbrush form with a well expressed chromomere-loop organization. the lampbrush chromosomes (lc) with most extended lateral loops were observed in the oocytes 0.5-1.5 mm in diameter. a mean loop contour length on the preparations from oocytes of such a diameter varied within 11-16 mkm. a comparison of the pigeon lc with those ...19892617670
aging and sex-related changes in the outer retina of japanese quail.age-related changes in the outer retina of japanese quail 3 months to 3 years of age have been assessed with light and electron microscopy. a major difference was observed between males and females in the accumulation of lipofuscin in retinal pigment epithelial (rpe) cells. females showed greater densities of lipofuscin granules, larger granules, and more lipofuscin per rpe cell than did males of comparable ages. in addition, a small but significant decrease (14-16%) in photoreceptor nuclear den ...19892612195
genetic studies on pancreatic proteinase in japanese quail.a genetic variation was found in pancreatic proteinase of japanese quail. in eight bands of proteinase isozymes, the variation of band 5 (presence or absence) was detected among quails. band 5 was identified as a chymotrypsin. the presence and absence of band 5 are controlled by a pair of allelic genes (prt-5a and prt-5a) on an autosomal locus, and gene prt-5a, causing expression of band 5, is dominant to gene prt-5a, a null allele for band 5. zymograms of proteinases and their zymogens were als ...19892695059
[heterochromatin regions of the chromosomes of the hen and japanese quail in mitosis and at the lampbrush stage].the mitotic and lampbrush chromosomes of the domestic fowl and japanese quail were analysed by fluorochrome staining technique. the lampbrush chromosomes of both the subjects displayed a typical "loop-chromomere" structure. three distinct kinds of loops were distinguished in gallus g. domesticus--normal, telomeric bows, and lumps. the former are distributed along the whole chromosome length. the latter and the bows were observed in subtelomeric and telomeric regions. by dna/rna specific acridine ...19892480013
effects of the noradrenergic neurotoxin dsp-4 on luteinizing hormone levels, catecholamine concentrations, alpha 2-adrenergic receptor binding, and aromatase activity in the brain of the japanese quail.previous investigations have established that dsp-4 reliably enhances the activating effects of testosterone on copulatory behavior in adult male quail. in the present study, we wanted to clarify the neurochemical changes that parallel these behavioral effects and to determine whether dsp-4 also affects non-behavioral steroid-dependent sexually dimorphic reproductive processes. we first showed using the palkovits microdissection technique combined with assay by high-performance liquid chromatogr ...19892568873
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