| [clinical trial of niclofolan (bay 9015) in the treatment of human opisthorchiasis. apropos of 51 cases]. | 51 refugees from south east asia infected with opisthorchis viverrini or clonorchis sinensis were included in a therapeutic study with niclofolan (bay 9015) at a dose of 1 mg/kg body weight given three times at intervals of 48 hours. clinical and biological tolerance was carefully controlled and in all cases proved to be very good or excellent particularly in several patients with various haemoglobinopathies or erythrocytal enzymopathies (g-6-pd deficiency). of the total of 51 cases, 17 were cur ... | 1980 | 7014011 |
| biliary lithiasis and helminthiasis. | the syndrome of oriental cholangiohepatitis is characterized by helminthiasis, choledocholithiasis often without cholecystolithiasis, biliary duct stricture and hepatic abscess. the common duct stones are usually multiple, black and friable. fourteen cases have been seen in recent immigrants to the united states. thirteen patients had choledocholithiasis, and 1 had viable flukes in the ducts. choledochoenterostomy is usually required because of multiple stones, including intrahepatic stones, or ... | 1981 | 7020457 |
| clinical evaluation of the therapeutic efficacy of praziquantel (embay 8440) against clonorchis sinensis infection in man. | | 1981 | 7023402 |
| [irregular anti-p1 allo-antibodies and sinensis clonorchiasis]. | a parasitological and immuno-hematological study was undertaken simultaneously in fifty south-east asian refugees at the time of their arrival in france. --in this series the frequency of individuals having a p2 erythrocyte phenotype is 80%. --54 % of these immigrants were found to be carriers of clonorchis sinensis, a parasite rarely found in europe. --in 40,7 % of these subjects infested by clonorchis sinensis, the following properties were disclosed concerning the p1 allo-antibody: slow-p1 re ... | 1981 | 7027412 |
| [acute cholecystitis and clonorchis sinensis infection]. | | 1981 | 7033799 |
| [biology of far eastern trematodes and the epidemiology of the diseases they cause. v. natural factors dictating the limits of the nosogeographic range of clonorchiasis in amur river region]. | | 1982 | 7045619 |
| anti-p1, allohemagglutinins associated with clonorchis sinensis and opisthorchis viverrini infections in patients from southeast asia. | an automated assay of anti-p1 allohemagglutinins has been carried out on sera of 61 individuals from southeast asia : 28 with clonorchiasis, 18 with opisthorchiasis and 15 control subjects. anti-p1 activity was detected in 61% of the opisthorchiasis sera, 57% of the clonorchiasis sera and in 26.6% of the control subjects. their concentration, in the sera, was low in control subjects and exceptionally high in clonorchiasis and opisthorchiasis (up to 13 and 22 times the maximum concentration of th ... | 1982 | 7051340 |
| [further observation of therapeutic effect of praziquantel on clonorchiasis (clonorchis sinensis)---experience with 100 cases (author's transl)]. | | 1982 | 7075363 |
| [the relationship between clonorchiasis (clonorchis sinensis) and other hepatobiliary diseases--clinical analysis of 2,214 cases (author's transl)]. | | 1982 | 7075365 |
| mucoepidermoid carcinoma of the bile duct. | three patients with mucoepidermoid carcinoma of the bile duct are described. in two patients the tumor arose from the common hepatic duct. mucoepidermoid carcinoma of the extrahepatic bile duct has not been previously reported. the clinical features and pathologic behavior of this rare type of tumor are similar to the usual biliary adenocarcinoma. the coexistence of clonorchis sinensis infestation and primary pyogenic cholangitis raises the possibility of an etiologic association. | 1982 | 7092364 |
| [praziquantel in the treatment of far eastern hepatic distomiasis caused by clonorchis sinensis or opisthorchis viverrini]. | forty-six patients infected with opistorchis viverrini and/or clonorchis sinensis, 24 males and 22 females, all laotian or vietnamese, aged 7 to 68, weighing 18 to 70 kg, were detected by parasitological stool examinations, numeration of eggs per gram of feces (e.p.g.). in this manner we observed 23 light infestations (1-999 e.p.g.), 20 moderate infestations (10,000-29,999 e.p.g.). before treatment, all these patients were submitted to a complete history and clinical examination with biological ... | 1981 | 7296740 |
| the bacteriology of recurrent pyogenic cholangitis and associated diseases. | ninety-five patients with recurrent pyogenic cholangitis had a range of specimens taken at laparotomy for bacterial culture. bacteria were isolated from 68% of cases. escherichia coli was the predominant pathogen. other aerobic and anaerobic intestinal bacteria were also isolated. liver biopsy, bile and gallstones were the most rewarding specimens for culture. infection was usually localized, but systemic infection occurred occasionally. the site of infection is probably in the liver parenchyma; ... | 1981 | 7310123 |
| praziquantel in clonorchiasis and opisthorchiasis. | a single stool examination revealed pathogenic intestinal parasites in 462 (58%) of 796 vietnamese and cambodian refugees. 56 (7.0%) were infected with clonorchis sinensis and/or opisthorchis viverrini. these patients received praziquantel in a dosage of 20 mg/kg bwt. p.day on 3 consecutive days. parasitological controls were completed after 12 months. no further excretion of eggs could be detected in 88% of the patients. concurrent infections with other trematodes and cestodes were also cured. ... | 1981 | 7345688 |
| [frequency and significance of parasitic infections in refugees from vietnam (author's transl)]. | in the course of the medical care which is provided for the refugees from southeast asia 100 persons were tested for intestinal parasites (helminths and protozoa). in addition serum samples were obtained from 72 of these and tested in several tests (cft, fat, iha and sft) using antigens of entamoeba histolytica, leishmania donovani, toxoplasma gondii, schistosoma spp., fasciola hepatica, echinococcus spp., trichinella spiralis and litomosoides carinii. in 49 persons infections with one, two or ... | 1980 | 7395245 |
| an imported case of clonorchis sinensis in sabah, malaysia. | | 1980 | 7436610 |
| intestinal parasites among indochinese refugees and mexican immigrants resettled in contra costa county, california. | stool examinations of 186 indochinese refugees and 90 immigrants from mexico resettled in contra costa, county, california, have shown that 60 percent of refugees and 39 percent of immigrants are infected with one or more species of pathogenic protozoa and helminths. the mean prevalences of infections among refugees and immigrants, respectively, were: hookworms, 25 and 2 percent; whipworm, 22 and 12 percent; ascaris, 20 and 12 percent; giardia lamblia, 11 and 11 percent; strongyloides, 9 and 1 p ... | 1981 | 7462932 |
| [comparative studies on the diagnosis of clonorchiasis by iest and ifat]. | both immunoenzymatic staining technique (iest) and indirect fluorescent antibody test. (ifat) with frozen sections of adult clonorchis sinensis as antigen were employed for detecting 51 cases with clonorchiasis and 50 healthy persons. the positive rate was 92% with iest and 88% with ifat. the results showed no significant statistic difference (p > 0.05). the false positive rates were 2% with the former and 4% with the latter. when sera from 22 cases with acute schistosomiasis, 20 cases with chro ... | 1993 | 7521804 |
| possible protective immunity in human opisthorchiasis. | chronic infections with the liver flukes opisthorchis viverrini and clonorchis sinensis affect over 30 million people in southeastern asia. with ongoing exposure, reinfection readily occurs following curative treatment and cumulative infections result in significant morbidity and a predisposition to cholangiocarcinoma. though protective immunity has never been described in human opisthorchiasis, heterogeneity in worm burden occurs and a small number of exposed residents of endemic areas remain a ... | 1994 | 7526321 |
| [cholangiolar carcinoma]. | cholangiocarcinoma affects both sexes equally, is more prevalent in individuals age 50 to 70. associations with many other diseases are known, in particular with primary sclerosing cholangitis, ulcerative colitis and parasitic infestation (clonorchis sinensis, opisthorchis viverrini). about 95% are histopathologically classified as adenocarcinoma. the localisation of the tumor determines clinical course and prognosis. if the tumor is located above the hepatic duct bifurcation, only one side of t ... | 1994 | 7531268 |
| clonorchiasis/opisthorchiasis in malaysians case reports and review. | clonorchiasis and opisthorchiasis are snail-transmitted trematode infections. the disease is endemic in many parts of asia. local case reports have been predominantly in chinese with a history of travel to endemic countries. thus far, 20 cases of liver fluke infestation have been reported in this country. this report presents another two cases of clonorchiasis and a case of opisthorchiasis. we also briefly review pertinent aspects of the disease. | 1995 | 7565193 |
| serum antibody response to opisthorchis viverrini antigen as a marker for opisthorchiasis-associated cholangiocarcinoma. | the liver flukes opisthorchis viverrini and clonorchis sinensis chronically infect over 30 million people in south-eastern asia, resulting in significant morbidity and a predisposition to cholangiocarcinoma (cca). liver fluke-associated cca carries a poor prognosis, partly because it is often detected at a late and advanced stage. the development of improved diagnostic methods, particularly for early cca, may improve chances of survival and cure. accordingly, we explored the use of immunological ... | 1994 | 7570848 |
| schistosomes, liver flukes and helicobacter pylori. iarc working group on the evaluation of carcinogenic risks to humans. lyon, 7-14 june 1994. | | 1994 | 7715068 |
| infection with liver flukes (opisthorchis viverrini, opisthorchis felineus and clonorchis sinensis). | | 1994 | 7715069 |
| [report on the first nationwide survey of the distribution of human parasites in china. 1. regional distribution of parasite species]. | a nationwide (taiwan province not included) survey of the distribution of human parasites in china during 1988-1992 was conducted under the auspices of the ministry of public health, with stratified masses randomly sampling. a total of 2,848 pilot sites in 726 counties with a population of 1,477,742 were surveyed, according to unified standard, unified diagnostic method and control quality. the overall infection rate of parasites was 62. 632%. among them, the infection rate was over 50% in 17 pr ... | 1994 | 7720194 |
| [studies on clonorchiasis sinensis control in sanshui city, guangdong province]. | during 1986 to 1988 and 1990 to 1992, dongyong township and guanyuan township in sanshui city, guangdong province were selected as demonstration areas for clonorchiasis sinensis control by using measures of repeated examination and treatment respectively. after two years' examination and treatment, the population infection rates were from 43.6% to 13.2% in dongyong township and from 78.5% to 36.3% in guanyuan township. the first intermediate host was alocimma longicornis, and the second intermed ... | 1994 | 7720206 |
| [experience with the parallel use of immunoenzyme analysis and copro-ovoscopy for assessing the clonorchiasis infectivity of the population of khabarovsk territory]. | the paper describes how enzyme immunoassay (eia) and copro-ovoscopy are concurrently used to define the spread of clonorchiasis among the population of the nanaĭsk district in the khabarovsk territory. it shows the efficiency of eia in seroepidemiological surveys and the possibility of its use in endemic areas. the sensitivity of eia to determine antibodies to clonorchis antigens was 70.58% and its specificity was 98.4%. the assay is recommended for wide application in clinical and epidemiologic ... | 1995 | 7770024 |
| [nationwide survey of the distribution of human parasites in china--infection with parasite species in human population]. | the infection rate of main species of parasites and their character by first nationwide survey of human parasites was made. the overall infection rate of human intestinal parasite and the infection rate of most species of parasites were higher in females than that in males. the infection rate according to the age group, the highest infection rate was found in the group aged 5-14 years. with regard to the relation between parasitic infections and occupations of the infected persons, the highest i ... | 1995 | 7788888 |
| [intestinal parasite and clonorchis sinensis infection among the inhabitants in the upper stream of taechong dam, kumgang (river)]. | the prevalence of intestinal parasites and clonorchis sinensis infection was observed among inhabitants in the upper stream of kumgang (river) from january to october 1991. a total of 743 fecal specimens was examined by cellophane thick smear and formalin-ether concentration technique. the parasite positive rate including helminth eggs and protozoan cysts was 40.8%, the positive rates for every species were: clonorchis sinensis 30.8%, metagonimus spp. 14.5%, fasciola spp. 0.7%, taenia spp. 1.5%, ... | 1994 | 7834237 |
| correlation of sonographic findings with histopathological changes of the bile ducts in rabbits infected with clonorchis sinensis. | clonorchiasis is an important parasitic disease of humans in korea. the present study intended to compare sonographic findings with histopathological changes in experimental clonorchiasis. eighteen new zealand white rabbits were infected with metacercariae of clonorchis sinensis, and examined 4, 10, and 22 weeks post-infection (pi). four infected rabbits were treated with praziquantel 10 weeks pi and were examined 12 weeks after treatment. sonography revealed mild to severe dilatation of the int ... | 1994 | 7834239 |
| clonorchiasis and metagonimiasis in the inhabitants along talchongang (river), chungwon-gun. | to evaluate the status of clonorchiasis and metagonimiasis of the inhabitants near talchongang (river) in chungwon-gun, chungchongbuk-do, the stools of 67 inhabitants were examined by formalin-ether sedimentation method from august to september, 1993. also freshwater fish caught in talchongang were examined by slide compression method. the egg positive cases of clonorchis sinensis and metagonimus sp. were 22 (32.8%), and 14 (20.9%), respectively. of 17 species of examined fish. 14 species were i ... | 1994 | 7834244 |
| egg positive rates of clonorchis sinensis and intestinal helminths among residents in kagye-ri, saengbiryang-myon, sanchong-gun, kyongsangnam-do. | stools of the residents in a village in saengbiryang-myon, sanchong-gun, kyongsangnam-do were examined for the eggs of intestinal helminths. in 1987, infection rate of 76 residents by clonorchis sinensis was 80.3% with mean eggs per gram of feces (epg) 27,781. c. sinensis-infected persons were treated once with praziquantel 60 mg/kg, q.i.d. seventeen persons (22.4%) infected by metagonimus yokogawai was coinfected with c. sinensis. in 1993, c. sinensis egg positive rate was 48.4% with mean epg 5 ... | 1994 | 7834245 |
| [an epidemiological study on clonorchiasis sinensis in hubei province]. | an epidemiological study on clonorchiasis sinensis was conducted in 62 counties and cities in hubei province during 1987-1991, and clonorchis sinensis was identified in 52 counties and cities. human population studies showed there were patients with clonorchiasis sinensis in 29 of 31 counties and cities investigated, with infection rates of 0.1%-16.2%. there were five species in two families of freshwater spiral shells as first intermediate host of clonorchis sinensis, 31 species in seven famili ... | 1994 | 7842884 |
| epidemiologic characteristics of clonorchiasis sinensis in guandong province, china. | extensive survey of the distribution of the liver fluke clonorchis sinensis in guandong province, china, has revealed high frequencies in human populations in some areas and absence in others. the distribution relates in part to the demography of first and second intermediate hosts and animal reservoir hosts, but it relates more clearly to the differing food habits of various populations in particular geographic areas. thus clonorchiasis is concentrated in the zhu jiang (pearl river) delta and a ... | 1994 | 7855642 |
| intestinal trematode infections in the villagers in koje-myon, kochang-gun, kyongsangnam-do, korea. | an epidemiological study for the intestinal trematode infection of the villagers was done in koje-myon, kochang-gun, kyongsangnam-do, korea in march, 1994. of 116 stool specimens examined, total helminthic ova positive cases were 13 (11.2%) and cumulative ova positive cases 21 (18.1%): echinostoma hortense 11 cases (9.5%), metagonimus sp. 6 cases (5.2%), and clonorchis sinensis 4 cases (3.4%). after the treatment and purgation, variable numbers of e. hortense, 6 to 227 per person, were collected ... | 1994 | 7953239 |
| liver function in clonorchis sinensis-infected rabbits. | nine rabbits were fed with clonorchis sinensis metacercariae (mc) and the blood samples chronologically obtained were analyzed biochemically. rabbits infected by less than 100 flukes were grouped into group i, and by 100-250 flukes into group ii. the serum level of alanine aminotransferase (alt) was increased from 3 weeks after the infection of the metacercariae (aim) and showed a peak at 8 weeks, and decreased from 12 weeks aim. the serum level of aspartate aminotransferase (ast) was raised to ... | 1994 | 7953243 |
| [an immunoenzyme test for the diagnosis of clonorchiasis and its use in endemic regions of the amur river basin]. | | 1993 | 8028571 |
| liver infested with clonorchis sinensis in orthotopic liver transplantation: a case report. | | 1994 | 8066747 |
| [preparation of membrane proteins of trichinella spiralis larva and application of them in detection with elisa]. | membrane proteins of muscle larva of trichinella spiralis (t.s) were isolated by using the non-ionic detergent triton x-114. at least fourteen components in the membrane proteins were separated with sds-page and then silver nitrate stain. the bands of them were located between 99-18kd mw level. the mw of chief bands were 94, 90, 47, 32 and 28kd. the sensitivity and specificity of these proteins were determined with elisa. they didn't cross react with sera of rabbits infected with toxocara canis ... | 1994 | 8070772 |
| promoting role of clonorchis sinensis infection on induction of cholangiocarcinoma during two-step carcinogenesis. | chronic clonorchis sinensis (cs) infection is etiologically related to cholangiocarcinoma (chca) in human and animals. this study was carried out to clarify the role of cs infection on dimethylnitrosamine (dmn)-induced cholangiocarcinogenesis. fifteen hamsters were administered with 15 ppm dmn for 4 weeks and one week later, the hamsters were infected with 15 metacercariae of cs (dmn-->cs group). the other 15 hamsters were infected with cs and after 5 weeks they were treated with the drug, prazi ... | 1994 | 8167103 |
| [second report on intestinal parasites among the patients of seoul paik hospital (1984-1992)]. | the results of fecal examination for helminth eggs and protozoan cysts in seoul paik hospital during 1984-1992 are reported. fecal specimens of a total of 52,552 out- or inpatients were examined by formalin-ether sedimentation and/or direct smear method. the overall egg positive rate of helminths was 6.5% and the cyst positive rate of protozoa 2.5%. the egg positive rate (number of positive cases) for each species of helminth was; clonorchis sinensis 3.2% (1,667), trichuris trichiura 2.0% (1,089 ... | 1994 | 8167105 |
| [immune reactions between excretory-secretory antigens and specific antibodies of clonorchis sinensis before and after praziquantel treatment in experimentally infected rabbits]. | this study was designed to evaluate the humoral immune reactions in clonorchiasis before and after praziquantel treatment. rabbits were infected with 150 or 450 metacercariae, treated on 4 and 8 1/2 months after infection, and observed for 13 months of posttreatment. infection controls were maintained for 22 months. antigen was the metabolic product of worms incubated in physiologic saline. the immune reactions of anti-clonorchis igg were observed using sds-page/immunoblot. during the infection ... | 1994 | 8167106 |
| a follow-up examination of intestinal parasitic infections of the army soldiers in whachon-gun, korea. | a follow-up stool examination was done to know the status of intestinal parasitic infections in army soldiers who were stationing in whachon-gun, kangwon-do, korea in 1993. of 233 examined soldiers, infections with clonorchis sinensis (0.4%), metagonimus spp. (0.9%), echinostoma hortense (0.4%), neodiplostomum seoulensis (0.4) and giardia lamblia (3/233) were found. e. hortense and n. seoulensis infections were each 75th, and 27th cases in korea. regular control program of intestinal parasitic i ... | 1994 | 8167111 |
| gallbladder adenocarcinoma with gallstone and calcified ova of clonorchis sinensis--a case report. | a case of gallbladder adenocarcinoma with gallstone and calcified parasitic ova of clonorchis sinensis was described. the patient, a 58-year-old chinese woman, presented with general malaise and jaundice. the gallbladder contained 3 stones in addition to the cancerous lesion. microscopically, we saw calcified parasitic ova of clonorchis sinensis associated with the stones. the relationships between clonorchis sinensis, stones and adenocarcinoma were discussed. | 1994 | 8205506 |
| [current status and the changing pattern of the prevalence of clonorchiasis in the inhabitants in sanchong-gun, kyongsangnam-do, korea]. | this study was conducted to evaluate the current endemicity and the transition mode of the clonorchis infection in sanchong-gun kyongsangnam-do. the areas of investigation, villages and schools surveyed, method and techniques used in this study were the same as in 1984. the egg positive rate of clonorchiasis in the general population of sanchong-gun was 37.6% out of 837 examined persons. in the schoolchildren, the rate was 9.7% out of 145 persons examined. in the intensity of the infection among ... | 1993 | 8241079 |
| clonorchis sinensis tropomyosin: cloning and sequence of partial cdna amplified by pcr. | c. sinensis total rna was containing large amount of 18s rrna but little 28s rrna. the size of the double-stranded cdna synthesized from poly (a)+ mrna was 0.4-4.2 kb long with tapering upto 9.5 kb. degenerated oligonucleotides (as 2 sense and 3 antisense primers) were designed on the conserved regions of the known tropomyosin amino acid sequences. from one out of the pcr amplifications using total cdna and matrix of primers, a specific gene product, 580 bp in size, was produced. upon southern h ... | 1993 | 8241088 |
| intestinal parasitic infections of korean army soldiers in whachon-gun, korea. | we examined stools of 113 soldiers of korean army in whachon-gun, korea in 1992. the eggs of clonorchis sinensis (7/113) and metagonimus sp. (3/113), and cysts of giardia lamblia (4/113) were detected. no eggs of soil-transmitted helminths were found. most of the clonorchis-infected soldiers (6/7) were recruited from kyongsangnam-do. | 1993 | 8241089 |
| detection of specific serum ige in clonorchiasis cases and analysis of clonorchis sinensis allergens. | specific serum ige levels of clonorchis sinensis in infected humans were measured by avidin-biotin elisa, and allergens from c. sinensis were identified by immunoblot and autoradiography. then, allergens fractionated by sephadex g-200 gel filtration were analyzed, and cross-reactive allergenic components of c. sinensis reacted with paragonimiasis sera were revealed. fourteen out of 15 c. sinensis egg-positives were found to be serum ige positive (absorbance > 0.27). of 14 ige-reacting allergen b ... | 1993 | 8259702 |
| cholangiocarcinoma: epidemiology, mechanisms of carcinogenesis and prevention. | cholangiocarcinoma is a relatively rare cancer; worldwide it accounts for an estimated 15% of liver cancers. in most areas, the etiology is rather obscure, and identified risk factors such as hepatolithiasis, inflammatory bowel disease, and exposure to thorotrast can account for only a small proportion of cases. in certain areas of southeast and eastern asia, however, incidence rates are very high, and here there is a strong association with infection with the liver flukes clonorchis sinensis an ... | 1993 | 8268770 |
| ct of clonorchis sinensis pancreatitis. | clonorchis sinensis infestation can involve the pancreatic duct and induce attacks of acute pancreatitis. ct findings in a case of clonorchis sinensis pancreatitis revealed significant enlargement of the pancreas with compression and obstruction of the common duct. medical treatment leads to resolution of the clinical and ct findings. the patient experienced a second episode of pancreatitis 3 yr later. ct examination documented the development of chronic pancreatitis with an acute exacerbation. | 1993 | 8283082 |
| intestinal parasites of cats purchased in seoul. | fecal samples of cats purchased in seoul were examined for helminth ova or protozoan oocysts from december 1987 to march 1988. out of the 41 samples, 31 (75.6%) were positive and 60 (146.3%) were cumulative positive for parasites. the followings were identified in the samples: eggs of toxocara cati, clonorchis sinensis, metagonimus sp., pharyngostomum cordatum, spirometra erinacei, taenia taeniaeformis and oocysts of isospora sp. from nine autopsied cats, larvae of anisakis simplex, adults of c. ... | 1993 | 8297895 |
| intestinal parasite infections in the inhabitants along the hantan river, chorwon-gun. | the prevalence of intestinal parasite infections in inhabitants at the reaches of the hantan river, chorwon-gun, korea, was observed from august 12 to september 14, 1993. of 465 people observed by cellophane thick smear and formalin-ether concentration method, 2 ascaris lumbricoides (unfertilized), 1 trichuris trichiura, 39 clonorchis sinensis and 16 metagonimus egg positive cases were found. after treatment, the metagonimus egg positive cases passed out flukes of metagonimus miyata type. of 68 ... | 1993 | 8297896 |
| turnover of biliary epithelial cells in clonorchis sinensis infected rats. | we performed bromodeoxyuridine (brdu) staining to observe the proliferation pattern of epithelial cells on the biliary mucosa in clonorchis sinensis infection. albino rats were infected with 100 metacercariae each and their livers were processed for histopathological observation after brdu injection. five to six sites in the liver of a rat were selected for paraffin section, and stained immunohistochemically to visualize brdu incorporating cells. the flukes were mainly in the common bile duct an ... | 1993 | 8343460 |
| imported opisthorchis viverrini and parasite infections from thai labourers in taiwan. | in order to determine the prevalence of intestinal parasites among labourers from thailand in taiwan, the stool samples from 1364 thai labourers were examined by the formalin-ether concentration method and 18.0% were found to be infected with one or more parasites. the infection rates of hookworm, opisthorchis viverrini, strongyloides stercoralis, enterobius vermicularis, ascaris lumbricoides, hymenolepis nana, capillaria philippinensis, schistosoma japonicum, echinostoma sp., entamoeba coli, gi ... | 1993 | 8354853 |
| precancerous lesions of the biliary tree. | malignant tumors may arise from any portion of the biliary tree. the term cholangiocarcinoma (cc) applies to both intra- and extrahepatic tumors. more than 95% of these tumors are adenocarcinomas. differentiation between cc and metastatic adenocarcinoma represents a difficult task for the pathologist. the presence of an intratumoral mini-ductal plate, and in situ carcinoma in bile ducts near the tumor and modulation from the bile duct towards parenchymal liver cells represent the major criteria ... | 1993 | 8389160 |
| effect of clonorchis sinensis infection and dimethylnitrosamine administration on the induction of cholangiocarcinoma in syrian golden hamsters. | the study was carried out to observe the effects of clonorchis sinensis infection on induction of cholangiocarcinoma in syrian golden hamsters to which 15 ppm dimethylnitrosamine (dmn) solution was administered for 8 weeks. the histopathological changes of the bile duct and liver cells were observed at the 11th week. in six of 8 hamsters (75%) which were treated with dmn and then infected with c. sinensis, the livers developed cholangiocarcinoma at 10 weeks after the infestation of c. sinensis. ... | 1993 | 8390293 |
| [effect of gamma-irradiation on infectivity of clonorchis sinensis metacercariae]. | the purpose of the present study was to observe the survival and development of clonorchis sinensis metacercariae in their final hosts after co-60 gamma irradiation exerting on both metacercariae isolated or in fish. guinea pigs or albino rats were orally infected by gavage. bio-assay, fecal examination for ova and dissection of infected animals were used for the estimation of minimum effective dose of gamma irradiation to control infectivity of clonorchis sinensis metacercariae. results showed ... | 1993 | 8403277 |
| endoscopic sphincterotomy in acute gallstone pancreatitis and cholangitis: a saudi hospital experience. | thirty-five patients with acute gallstone pancreatitis and/or cholangitis underwent endoscopic sphincterotomy. in 15 out of 18 patients with acute gallstone pancreatitis, common bile duct (cbd) stones, 5 of which were impacted, were removed. this resulted in prompt improvement in 12 of these patients. eleven patients had acute gallstone cholangitis in ten of whom--including one patient who had cholangiocarcinoma associated with clonorchis sinensis--cbd stones were extracted. six other patients h ... | 1993 | 8406313 |
| secretions of the biliary mucosa in experimental clonorchiasis. | the histological change of the biliary mucosa in clonorchiasis is characterized as adenomatous hyperplasia, and cross-sectioned mucosa looks like intestinal mucosa. in addition to the glandular hyperplasia, the metaplasia of mucin secreting cells is also known. the present study investigated the presence of intestinal secretion from the biliary mucosal cells of rabbits and rats with clonorchis sinensis infection. the rabbit was infected with 300 and the rat was infected with 100 metacercariae of ... | 1993 | 8512895 |
| antigenic protein fractions of metagonimus yokogawai reacting with patient sera. | antibody test is sometimes necessary for the diagnosis of acute human metagonimiasis because eggs may not be detected in stool. the antibody test (elisa) was evaluated for its significance by reacting human sera from clinically diagnosed metagonimiasis, fascioliasis, clonorchiasis and paragonimiasis with 4 crude extracts of metagonimus yokogawai (metacercariae), adults of fasciola hepatica, clonorchis sinensis and paragonimus westermani. by elisa, 10 of 11 metagonimiasis sera showed the highest ... | 1993 | 8512898 |
| antibodies in serum of patients with clonorchiasis before and after treatment. | sera of 31 patients infected with clonorchis sinensis were examined using fraction 1 antigen by elisa during a one-year observation. the results of elisa with igs, igg and iga demonstrated high sensitivity (100%, 100% and 90%) and specificity (100%, 100% and 87%). sera specific igs and igg were significantly decreased in the 3rd month after treatment with praziquantel (25mg/kg body weight in one dose), and iga was significantly decreased in the 1st month (paired t-test, p < 0.05). no eggs were f ... | 1995 | 8525396 |
| cytotoxicity of a cysteine proteinase of adult clonorchis sinensis. | to clarify the correlation of the proteinase activity with pathogenicity of clonorchis sinensis, the proteinase activity either in excretory-secretory products (esp) or in crude extracts of adult c. sinensis was examined. substrate gel electrophoresis of the esp and crude extracts revealed four distinct enzyme bands, which were differently inhibited by the specific proteinase inhibitors. the proteinase of the esp with molecular mass of 24 kda, was purified 23-fold with 14.5% yield by spectra gel ... | 1995 | 8528628 |
| [characteristics and recent trends in endemicity of human parasitic diseases in china]. | an analysis of the nationwide survey of the distribution of human parasites in the light of the literature previously published, two major trends in the endemicity of parasitic diseases in china was observed. for one trend, the infection rate of e. histolytica, fasciolopsis buski and soil-transmitted helminthasis etc. declined markedly. the second trend was that the prevalence of food-transmitted parasitic diseases (trichinella spiralis, clonorchis sinensis, paragonimiasis, cysticercosis) and hy ... | 1995 | 8556800 |
| prevalence of intestinal parasites and association with symptoms in southeast asian refugees. | we prospectively evaluated 201 southeast asian refugees in a primary care clinic for intestinal parasites and their association with gastrointestinal symptoms. patients completed a standardized screening questionnaire which elicited information on demographic factors and eight gastrointestinal symptoms, and stools were collected for ova and parasite examination. although 89% had been living in the u.s.a. for more than 1 year, intestinal parasites were found in 37 (18%) patients and pathogenic pa ... | 1995 | 8576294 |
| image analytical observation on the growth and development of clonorchis sinensis in rats. | for the two-dimensional observation on the growth and development of clonorchis sinensis, an image analysis system (ibas 2000, kontron, germany) was used in this study. on 3, 6, 9, 12, 15, 21, 30 and 90 days of infection, 474 worms were collected from rats infected with 50 metacercariae each. the overall recovery rate was 31.6%. the worms grew rapidly in their length and width up to 30 days of infection and then, did slowly to 90 days of infection. however, the growth pattern of body area was no ... | 1995 | 8591005 |
| acute clonorchiasis. | a 42-year-old chinese woman developed 3 weeks of swinging fever, rash, malaise, and discomfort at the right upper quadrant of the abdomen. acute clonorchis sinensis infection eventually became evident and the patient responded to praziquantel. although acute infestation is usually asymptomatic, occasional cases suffer severe symptoms and present difficulties in clinical diagnosis. clonorchiasis is endemic in south east asia. with the increasing popularity of travel to these countries and the glo ... | 1995 | 8685651 |
| [clonorchiasis]. | | 1995 | 8749418 |
| [study of an ancient corpse of the warring states period unearthed from tomb no. 1 at guo-jia gang in jingmen city (a comprehensive study)]. | an ancient female corpse excavated from the robbed tomb no. 1 at guo-jia-gang in jingmen city of hubei province was studied. it was confirmed that the corpse was buried more than 2,300 years ago, namely at the middle stage of the warring states period and is the earliest one of the ancient coffin corpses unearthed in china so far. it is of the same type as the ancient corpses of weatern han dynasty excavated from tomb no. 1 at ma-wang-dui in changsha city and from the tomb no. 168 at phoenix hil ... | 1996 | 8758736 |
| liver and intestinal flukes. | a number of trematodes besides schistosomes parasitize humans and domesticated animals. although they do not have as great a public health impact as schistosomiasis, they are prevalent in southeast asia as well as among the greater than 1 million immigrants from this region to north america. the human biliary flukes include c. sinensis, o. viverrini, and o. felineus. these chronic infections are often asymptomatic but over time may cause biliary thickening, cholangitis, and a predisposition to c ... | 1996 | 8863043 |
| hepatitis b and c virus, clonorchis sinensis for the risk of liver cancer: a case-control study in pusan, korea. | liver cancer mortality in korea is the highest in the world. hepatitis b and c viruses (hbv, hcv) are known to be the major risk factors of hepatocellular carcinoma (hcc). cholangiocarcinoma (clg) accounts for more than 20% of liver cancer in the pusan area. in korea, the different roles of known risk factors in the development of hcc or clg have not been adequately evaluated. | 1996 | 8921477 |
| the infestation states and changing patterns of human infecting metacercariae in freshwater fish in kyongsang-do and kyonggi-do, korea. | the infestation rates and abundances of human infecting metacercariae (clonorchis sinensis, metagonismus spp., centrocestus armatus, echinostoma hortense, echinochasmus japonicus, clinostomum complanatum) in freshwater fish were investigated at the three river areas-taewhagang (river), hyongsangang (river), nakdonggang (river) -in kyongsang-do and at four streams-yonpungchon, munsanchon, kyonganchon, and konjiamchon-in kyonggi-do, korea in 1994-1995. the fish caught at taewhagang were heavily in ... | 1996 | 8925250 |
| [cholangitis due to clonorchis sinensis detected in escherichia coli septic shock]. | | 1996 | 8926886 |
| the use of liver grafts infested with clonorchis sinensis for orthotopic liver transplantation. | in the orient, millions are known to have clonorchis sinensis (biliary trematodiasis) infestation. when these infested livers become available as donor organs, there are potentially serious implications that the transplant team would need to consider. we report the use of two such infested livers, one from a cadaveric donor and the other from a live related donor, for orthotopic liver transplantation. the parasite was encountered not only during organ procurement, but also caused early postopera ... | 1996 | 8935604 |
| a carbohydrate antigen of clonorchis sinensis recognized by a species-specific monoclonal antibody. | the enzyme-linked immunosorbent assay (elisa)-inhibition test using a clonorchis sinensis species-specific mouse monoclonal antibody (mab), cshyb 0605-23, showed increased specificity over the conventional elisa used for serodiagnosis of clonorchiasis. to characterize the corresponding antigen further, the mab was tested against polysaccharide, protein and glycolipid fractions obtained from a crude extract of c. sinensis adult worms, using chloroform, methanol and phenol extractions. only the po ... | 1996 | 9017915 |
| heterogeneity of the "oval-cell" response in the hamster liver during cholangiocarcinogenesis following clonorchis sinensis infection and dimethylnitrosamine treatment. | small intraportal "oval" cells which appear in the livers of humans and experimental animals after liver injury, are suspected to be early progenitor cells for both hepatocytes and bile duct cells, as well as cells of origin of hepatocellular and cholangiocellular carcinomas. | 1997 | 9210619 |
| immunoblot patterns of clonorchiasis. | clonorchis sinensis is a liver fluke which is the most prevalent helminth of humans in korea. the better diagnostic measure of clonorchiasis is required for its nationwide control program. the present study observed antigenic bands of c. sinensis and reacting immunoglobulins in serum of infected residents. adult c. sinensis were recovered from experimentally infected rabbits and soluble crude extract of the worms was used as the antigen after supplementation of e-64, a cysteine proteinase inhibi ... | 1997 | 9241982 |
| changing patterns of clonorchis sinensis infections in kyongbuk, korea. | studies were conducted from may, 1993 to april, 1995 to determine the changing patterns of infection by the liver fluke, clonorchis sinensis, among residents and fish hosts in kyongbuk province. the infection rate among residents was 7.7% by stool examination. the rate in males (11.3%) was significantly higher than females (4.1%). positive rate of intradermal test was 27.6% in the same population. the special type of a simple catalytic model was applied for the analysis of intradermal positive r ... | 1997 | 9335180 |
| [infection status with trematode metacercariae in the fresh-water fish from chunamchosuchi (pond), uichang-gun, kyongsangnam-do, korea]. | the present study was performed to analyze the infection status of trematode metacercariae in fishes caught from chunamchosuchi (pond) located in uichang-gun, kyongsangnam-do. a total of 130 freshwater fish of 5 species was collected by a fish net and fish traps from november, 1995 to may, 1996. they were examined under a stereomicroscope after artificial digestion with pepsin-hcl solution. a total of 8 species of metacercaria, i.e. clonorchis sinensis, echinochasmus japonicus, cyathocotyle orie ... | 1997 | 9335181 |
| [experience with a clinical parasitological examination in a clonorchiasis focus in the amur river region]. | the clinical manifestations of clonorchiasis were studied in 190 patients in the amur river region. the severity of the disease correlated with the excretion rates of clonorchis eggs. the peculiarity of the region is a rather low egg excretion; 66.8% of patients excreted as many as 100 eggs/g, 27.3%, up to 1000 eggs/g. most examinees (94.3%) suffered from chronic gastroduodenitis and functional disorders of the biliary system. | 1997 | 9445987 |
| laparoscopic view of clonorchis sinensis. | | 1998 | 9492742 |
| hepatolithiasis and biliary parasites. | hepatolithiasis, or the presence of intrahepatic stones, is prevalent in east asia and is characterized by the finding of stones within the intrahepatic bile ducts proximal to the confluence of the right and left hepatic ducts. bile stasis and bacterial infection have been incriminated as the major aetiopathogenic factors. clinical features include recurrent pyogenic cholangitis, multiple liver abscesses, secondary biliary cirrhosis and cholangiocarcinoma. the goals of management include accurat ... | 1997 | 9512805 |
| a clonorchis sinensis-specific antigen that detects active human clonorchiasis. | a clonorchis sinensis-specific antigen in excretory-secretory product of c. sinensis (cse) was assessed in human clonorchiasis by immunoblot. thirty and 7 kda antigens of cse2, one of four different batches of cses reacted strongly with infection sera from clonorchiasis patients; however, the antigens reacted weakly with 6-month post-treatment sera from praziquantel-cured cases, but were still highly detected by the sera from praziquantel-failed patients, indicating that the 30 and 7 kda antigen ... | 1998 | 9529862 |
| bacterial and parasitic cholangitis. | bacterial cholangitis is a clinically defined syndrome caused by the regurgitation of infected bile into the circulation. the pathogenic mechanism is unclear, and systemic sepsis may not occur. prerequisite conditions are the presence of microorganisms in the bile and increased biliary pressure. bacteria that commonly cause cholangitis are escherichia coli, klebsiella, enterococcus, enterobacter, pseudomonas, and anaerobes. although most infections are polymicrobial, this situation may not alway ... | 1998 | 9581592 |
| viability of metacercariae of clonorchis sinensis in frozen or salted freshwater fish. | metacercariae of clonorchis sinensis were collected from freshwater fish (pseudorasbora parva) after storage in a freezer at -12 degrees c for 10-20 days, in a freezer at -20 degrees for 3-7 days, or treating with heavy salt (fish/salt = 10 gm/3 gm) at 26 degrees for 5-15 days. the metacercariae from the frozen fish were inoculated into 30 rats and eight rabbits, and those from the salted fish into 33 rats. metacercariae from freshwater fish stored at -12 degrees for 10-18 days or -20 degrees fo ... | 1998 | 9602382 |
| epidemiological survey on clonorchiasis sinensis in yangxin county of hubei province of pr china. | an epidemiological survey of clonorchiasis was conducted at panqiao township of yangxin county of hubei province from june to november, 1993. the positive rate of cercaria in the body of intermediate hosts, parafossarulus stratulus and alocinma longicornis was 12.25% and 3.84% respectively. positive rates of metacercariae in the bodies of pseudonaphona parva was 48.15%, ctenopharyngodon idellus 17.24% and hypophthalmichthys nobilis 18.18%. positive rate of eggs in the feces of cats was 36.36% an ... | 1997 | 9656349 |
| metacercariae in fishes of sun moon lake which is an endemic area for clonorchis sinensis in taiwan. | the sun moon lake in central taiwan is a known endemic area for clonorchiasis. of the 45 fresh water fish, hemiculter leucisculus, from the lake that were examined by artificial gastric juice digestion in october 1995, all were found to harbor metacercariae in their muscle. the number of metacercariae isolated from each fish ranged from 2 to 2,185, with an average of 254. a total of 11,443 metacercariae was collected from the 45 fish. of the 4,223 metacercaria that were examined under light micr ... | 1997 | 9656382 |
| clonorchiasis in bone marrow transplant recipients. | among 380 bone marrow transplant (bmt) recipients, five cases (1.3%) of clonorchiasis were observed from 1991 to 1996. clonorchis sinensis infection was evident in the results of stool examinations performed for screening purposes 7 days before bone marrow transplantation. salmonella species were isolated concomitantly from the stools of two of the five patients. none of the patients had symptoms due to clonorchiasis. ultrasonography did not show dilated hepatobiliary ducts, stones, or periporta ... | 1998 | 9709891 |
| two endemic foci of heterophyids and other intestinal fluke infections in southern and western coastal areas in korea. | two endemic foci of heterophyid infections were discovered in coastal villages of puan-gun, chollabuk-do, and sachon-gun. kyongsangnam-do, korea. fecal examinations were performed on 153 inhabitants of puan-gun and 138 of sachon-gun, using cellophane thick smear and formalin-ether sedimentation technique. the helminth egg and/or protozoan cyst positive rate was 21.5% (33/153) in puan-gun and 39.1% (54/138) in sachon-gun. in puan-gun, the egg positive rate of heterophyids was the highest, 17.6%, ... | 1998 | 9755586 |
| immunodiagnosis of clonorchiasis using a recombinant antigen. | a cdna expression library of clonorchis sinensis adult worm was constructed, and screened out immunologically. one clone, pbcs31, was selected in view of its predominant reactivity with an experimentally infected rabbit serum. recombinant c. sinensis antigen with 28 kda as a beta-galactosidase fusion protein produced in escherichia coli was identified by immunoblot analysis. the cloned gene was composed of 16 copies of a 30 base pair repeat and an additional 320 bases. the deduced amino acid seq ... | 1998 | 9755589 |
| in vitro effects of various neuropharmacological agents on the motility of adult clonorchis sinensis. | stimulatory effects were observed in vitro when 5-ht was applied to whole worm preparations of clonorchis sinensis. the stimulatory action of 5-ht was antagonized by tryptophol, clomipramine and imipramine. strychnine remarkably stimulated motility. the action of strychnine was enhanced by 5-ht but inhibited by tryptophol. gaba, phenylephrine, isoproterenol, dibenamine and phentolamine showed little influence on motility. inhibitory effects were caused by eserine, arecoline, carbachol, dmpp and ... | 1998 | 9780596 |
| [establishment of hybridoma technique and study on fusion conditions of hybridoma cells]. | | 1997 | 9868069 |
| synthesis of praziquantel derivatives and their in vitro activity against adult clonorchis sinensis. | several praziquantel derivatives have been prepared by the acylation of compound 5, and examined on their biological activity in vitro a against adult clonorchis sinensis collected from rabbits infected with metacercariae which was isolated from pseudorasbora parva, a second intermediate host, captured in nakdong river in korea. | 1998 | 9868549 |
| control of clonorchiasis by repeated praziquantel treatment and low diagnostic efficacy of sonography. | in korea, clonorchis sinensis infection is still highly prevalent because case detection in the field is difficult and the detected cases used to be incompletely cured due to treatment failure. the present study tried to control clonorchiasis in an endemic village by repeated treatments with praziquantel every 6 months and to evaluate sonography as a diagnostic measure. by stool examinations, the egg positive rate in the endemic village was 22.7%, but it decreased to 19.6% at 6 months, 15.1% at ... | 1998 | 9868890 |
| epidemiology of clonorchiasis in ninh binh province, vietnam. | clinical and stool examinations for clonorchiasis were carried out in an endemic area, kim son district, ninh binh province, vietnam. stool examination with the kato-katz technic revealed that in 306 residents selected randomly, 42 people (13.7%) were infected with clonorchis sinensis. the rate was biased towards men (23.4%) as opposed to women (1.5%) and increased with age. no children younger than 10 years old were infected, reflecting difference in a chance for acquisition of infection throug ... | 1998 | 9886107 |
| biliary papillary hyperplasia with clonorchiasis resembling cholangiocarcinoma. | infection by the liver fluke clonorchis sinensis is very common in the far east. it causes low grade inflammatory changes and proliferation in the biliary tree. initially there is desquamation of the biliary epithelium, followed by hyperplasia and adenomatous proliferation. cholangiocarcinomas are potential long term complications. we present a case of biliary papillary hyperplasia with clonorchiasis resembling cholangiocarcinoma in a 69-yr-old korean man. early recognition of biliary hyperplasi ... | 1999 | 10022657 |
| [clonorchiasis]. | | 1999 | 10201267 |
| pancreatitis in association with clonorchis sinensis infestation: ct evaluation. | objective: the purpose of this study was to describe the ct characteristics in patients with clonorchis sinensis pancreatitis. conclusion: ct showed that in the presence of diffuse mild intrahepatic bile duct dilatation, the enlargement of the body or tail (or both) of the pancreas, with a cluster of small cystic changes within the pancreatic parenchyma, was strong evidence for the possibility of c. sinensis pancreatitis. | 1999 | 10227505 |
| identification of ige-reacting clonorchis sinensis antigens. | clonorchis sinensis is a liver fluke and it is the most prevalent human parasite in korea at present. the parasite infection induces immune responses, characteristically an increased production of parasite-specific ige in the host. major ige-reacting c. sinensis antigens in infected humans have been protein bands with mws of 15, 28, 37, 45, 51, 56, 62, 66, 74, 97 and 160 kd identified by immunoblot analysis. individual variations of the ige binding pattern to c. sinensis antigens have also been ... | 1999 | 10333723 |
| prevention of bile duct cancer in primary sclerosing cholangitis. | patients with primary sclerosing cholangitis (psc) have a substantial predisposition to develop bile duct carcinoma. the mechanism is still unclear but the observation that patients with chronic clonorchis sinensis infection are also prone to cholangiocarcinoma suggests a role for long standing inflammation. however, there is still no effective medical therapy which can halt the progression of the disease or prevent the development of cholangiocarcinoma. the only effective treatment for advanced ... | 1999 | 10436824 |
| risk factors for biliary tract carcinogenesis. | cholangiocarcinoma has a worldwide distribution which accounts for about 10-15% of all cases of primary hepatobiliary malignancy. although, in the majority of cases, no aetiological factor can be identified, a number of risk factors have been shown to be important in the development of cholangiocarcinoma; most of these factors share long standing inflammation and chronic injury of the biliary epithelium. primary sclerosing cholangitis is an uncommon disease, characterized by stricturing, fibrosi ... | 1999 | 10436847 |
| an eighty-four-year-old man with fever and painless jaundice: a case report and brief review of clonorchis sinensis infection. | | 1999 | 10467158 |