| anaerobic oral flora in the north american black bear (ursus americanus) in eastern north carolina. | microbial flora can provide insight into the ecology and natural history of wildlife in addition to improving understanding of health risks. this study examines the anaerobic oral flora of hunter killed black bears (ursus americanus) in eastern north carolina. oral swabs from the buccal and lingual supragingival tooth surfaces of the first and second mandibular and maxillary molars of 22 black bears were inoculated onto brucella blood agar plates supplemented with hemin and vitamin k after trans ... | 2012 | 22503889 |
| antibiotic resistance in human peri-implantitis microbiota. | because antimicrobial therapy is often employed in the treatment of infectious dental implant complications, this study determined the occurrence of in vitro antibiotic resistance among putative peri-implantitis bacterial pathogens. | 2014 | 23551701 |
| constant high adrenal fdg uptake in pet/ct associated with mitochondrial disease. | we describe a patient with the m.3243a>g mitochondrial dna mutation who developed sepsis caused by streptococcus constellatus. in the acute phase of illness, abnormally high uptake of (18)f-fdg was observed in both adrenal glands that appeared anatomically normal. in repeated imaging six months later the adrenal uptake had diminished but remained clearly elevated. we did not observe high adrenal fdg uptake as in the patient described here among 30 patients with staphylococcus aureus sepsis that ... | 2014 | 24554338 |
| is sinusitis innocent?--unilateral subdural empyema in an immunocompetent child. | subdural empyema related to streptococcus constellatus is extremely rare in an immunocompetent child, and also there is no reported case along with staphylococcus lugdunensis infection. although streptococcus constellatus has been determined as a co-pathogen with anerobic bacteria in many infections, it has not been reported in combination with staphylococcus lugdunensis. the authors describe a case of previously healthy 16-y-old child with unilateral subdural empyema due to these bacteria. sinu ... | 2015 | 25967257 |
| pelvic peritonitis during biologic therapy for rheumatoid arthritis: a case report and review of the literature. | infections are recognized as major complications during therapy with biologics and other immunosuppressant drugs. the respiratory tract, bone, joint, skin, and soft tissues are well known sites of infection in patients with rheumatoid arthritis (ra) treated by biologics or other immunosuppressants. it is known that patients with intra-abdominal infections may develop tuberculous peritonitis during biologic therapy. however, non-tuberculous pelvic peritonitis is rare. | 2014 | 25332867 |
| [investigation on the identification accuracy for group b streptococcus by automated identification system raisus]. | since we had experienced a case of misidentification for group b streptococcus (gbs) (streptococcus agalactiae) by automated identification system raisus, we have investigated the identification accuracy for gbs by automated identification system raisus system using our stock isolated of gbs. among 31 strains including standard strain atcc13813 of gbs, 30 strains were identified as gbs, while only 1 strain was misidentified as streptococcus constellatus. we have needed 3 hours to identify 29 tru ... | 2012 | 23547480 |
| case-control study of pneumonia patients with streptococcus anginosus group bacteria in their sputum. | in recent years, streptococcus anginosus group (sag) bacteria are becoming increasingly recognized as important pneumonia-causing pathogens. although several small studies have been reported, the features of sag pneumonia remain unclear, because the identification of sag from sputum cultures is not routinely performed in most microbiology laboratories. the aim of this study was to elucidate the clinical characteristics of sag pneumonia. | 2016 | 27681235 |
| streptococcus anginosus (milleri) group strains isolated in poland (1996-2012) and their antibiotic resistance patterns. | streptococcus anginosus, streptococcus intermedius and streptococcus constellatus form a group of related streptococcal species, namely the streptococcus anginosus group (sag). the group, previously called "milleri" had been rarely described until 1980/1990 as source of infections. nowadays sag bacteria are often described as pathogens causing predominantly purulent infections. the number of infections is highly underestimated, as sag strains are often classified in the microbiology laboratory a ... | 2016 | 27281992 |
| the streptococcus milleri group in chronic obstructive pulmonary disease. | s. anginosus, constellatus and intermedius, also known as the streptococcus milleri group (smg) are three streptococcal species more frequently detected in cases of invasive disease, abscesses and empyema in particular. recent research suggests they play a role in exacerbations of cystic fibrosis (cf). owing to poor recovery on standard culture media and difficult differentiation from non-pathogenic streptococci, smg may be underdiagnosed in routine settings. we aimed to establish the incidence ... | 2016 | 27132809 |
| comparing matrix-assisted laser desorption ionization-time of flight mass spectrometry and phenotypic and molecular methods for identification of species within the streptococcus anginosus group. | the heterogeneity of members of the streptococcus anginosus group (sag) has traditionally hampered their correct identification. recently, the group was subdivided into 6 taxa whose prevalence among human infections is poorly described. we evaluated the accuracy of the rapid id32 strep test, matrix-assisted laser desorption ionization-time of flight mass spectrometry (maldi-tof ms), and a pcr multiplex method to identify 212 sag isolates recovered from human infections to the species and subspec ... | 2015 | 26354817 |
| streptococcus constellatus causing septic thrombophlebitis of the right ovarian vein with extension into the inferior vena cava. | introduction. streptococcus constellatus collectively with streptococcus anginosus and streptococcus intermedius constitute the streptococcus anginosus (formerly streptococcus milleri) group. though they are commonly associated with abscesses, bacteremia with subsequent septic thrombophlebitis is extremely rare, and resulting mortality is infrequent. case presentation. we report a case of a previously healthy 60-year-old african american female who presented with streptococcus constellatus bacte ... | 2015 | 26171262 |
| identification of the 'streptococcus anginosus group' by matrix-assisted laser desorption ionization--time-of-flight mass spectrometry. | matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (maldi-tof ms) provides rapid, accurate and cost-effective identification of a range of bacteria and is rapidly changing the face of routine diagnostic microbiology. however, certain groups of bacteria, for example streptococci (in particular viridans or non-haemolytic streptococci), are less reliably identified by this method. we studied the performance of maldi-tof ms for identification of the 'streptococcus anginosus ... | 2014 | 24917618 |
| molecular pathogenicity of streptococcus anginosus. | streptococcus anginosus and the closely related species streptococcus constellatus and streptococcus intermedius, are primarily commensals of the mucosa. the true pathogenic potential of this group has been under-recognized for a long time because of difficulties in correct species identification as well as the commensal nature of these species. in recent years, streptococci of the s. anginosus group have been increasingly found as relevant microbial pathogens in abscesses and blood cultures and ... | 2014 | 24848553 |
| an unusual case of streptococcus anginosus group pyomyositis diagnosed using direct 16s ribosomal dna sequencing. | bacteria belonging to the streptococcus anginosus group (streptococcus intermedius, streptococcus constellatus and streptococcus anginosus) are capable of causing serious pyogenic infections, with a tendency for abscess formation. the present article reports a case of s anginosus group pyomyositis in a 47-year-old man. the pathogen was recovered from one of two blood cultures obtained from the patient, but speciation was initially not performed because the organism was considered to be a contami ... | 2014 | 24634686 |
| a streptolysin s homologue is essential for β-haemolytic streptococcus constellatus subsp. constellatus cytotoxicity. | streptococcus constellatus is a member of the anginosus group streptococci (ags) and primarily inhabits the human oral cavity. s. constellatus is composed of three subspecies: s. constellatus subsp. constellatus (scc), s. constellatus subsp. pharyngis and the newly described subspecies s. constellatus subsp. viborgensis. although previous studies have established that scc contains β-haemolytic strains, the factor(s) responsible for β-haemolysis in β-haemolytic scc (β-scc) has yet to be clarified ... | 2014 | 24600025 |
| invasive streptococcus anginosus group infection-does the species predict the outcome? | to determine whether there is an association between the species of streptococcus anginosus group (sag) bacteria and the clinical outcome. | 2014 | 24215937 |
| identification, clinical aspects, susceptibility pattern, and molecular epidemiology of beta-haemolytic group g streptococcus anginosus group isolates from central taiwan. | no literature is available on the prevalence and clinical aspects of beta-haemolytic group g streptococcus anginosus group in central taiwan. in this study, we used 16s rrna gene sequencing and 16s-23s rdna intergenic spacer sequencing (where necessary) as the gold standard for molecular identification. twenty-seven s. anginosus group isolates were identified from 273 beta-haemolytic ggs isolates collected from patients in central taiwan between february 2007 and august 2011. of the 27 isolates, ... | 2013 | 23632249 |
| identification of β-haemolysin-encoding genes in streptococcus anginosus. | streptococcus anginosus is an emerging pathogen, but little is known about its virulence factors. to detect the genes responsible for β-haemolysis we performed genomic mutagenesis of the β-haemolytic s. anginosus type strain atcc 12395 using the vector pghost9:iss1. integration site analysis of 15 non-haemolytic mutants identified a gene cluster with high homology to the genes of the streptolysin s (sls) encoding sag gene cluster of s. pyogenes. the gene cluster harbours 10 open reading frames d ... | 2013 | 23594064 |
| taxonomy of the anginosus group of the genus streptococcus and description of streptococcus anginosus subsp. whileyi subsp. nov. and streptococcus constellatus subsp. viborgensis subsp. nov. | the anginosus group of the genus streptococcus has been the subject of much taxonomic confusion, which has hampered the full appreciation of its clinical significance. the purpose of this study was to critically re-examine the taxonomy of the anginosus group, with special attention to β-haemolytic, lancefield group c strains, using multilocus sequence analysis (mlsa) combined with 16s rrna gene sequence and phenotypic analyses. phylogenetic analysis of concatenated sequences of seven housekeepin ... | 2013 | 23223817 |
| presumed hydrogen sulfide-mediated neurotoxicity after streptococcus anginosus group meningitis. | hydrogen sulfide is an environmental toxicant and gaseous neurotransmitter. it is produced enterically by sulfur-reducing bacteria and invasive pathogens including streptococcus anginosus group, salmonella and citrobacter. we describe putative focal hydrogen sulfide neurotoxicity after streptococcus constellatus meningitis, treated with adjunctive sodium nitrite and hyperbaric oxygen therapy. | 2013 | 23014355 |
| real-time monitoring of the adherence of streptococcus anginosus group bacteria to extracellular matrix decorin and biglycan proteoglycans in biofilm formation. | members of the streptococcus anginosus group (sags) are significant pathogens. however, their pathogenic mechanisms are incompletely understood. this study investigates the adherence of sags to the matrix proteoglycans decorin and biglycan of soft gingival and alveolar bone. recombinant chondroitin 4-sulphate(c4s)-conjugated decorin and biglycan were synthesised using mammalian expression systems. c4s-conjugated decorin/biglycan and dermatan sulphate (ds) decorin/biglycan were isolated from ovin ... | 2012 | 22835945 |
| milleri group streptococcus--a stepchild in the viridans family. | the purpose of this investigation was to provide a comprehensive review of the pathogenic role and spectrum of disease of milleri group streptococci, with special attention to bloodstream invasion and to possible differential roles among the three species. all consecutive isolates of milleri group streptococci from any anatomic source, during a 37-month period, in a tertiary care teaching hospital in tel-aviv, israel, were thoroughly investigated. identification to the species level was performe ... | 2012 | 22391759 |
| pyopneumothorax secondary to streptococcus milleri infection. | we report a case of a 46-year-old malay woman with underlying hypothyroidism post thyroidectomy who presented with worsening breathlessness, orthopnoea, productive cough and left-sided pleuritic chest pain of 3 days duration. chest x-ray on admission showed left-sided massive hydropneumothorax. pleural tapping revealed empyema. a chest tube was inserted immediately. the culture of pleural fluid grew streptococcus constellatus the patient was treated with antibiotics for a total of 6 weeks and un ... | 2016 | 27881590 |
| thalamic abscess caused by a rare pathogen: streptococcus constellatus. | streptococcus constellatus is a microorganism that lives commensally in the oropharyngeal region, urogenital region, and intestinal tract. however, it can cause infection in patients with certain predisposing factors. rarely, this microorganism can cause a brain abscess. thalamic localization of brain abscesses is much rarer than abscesses in other locations of the brain. brain abscess caused by streptococcus constellatus are very rarely been reported in the literature. we present a rare case of ... | 2016 | 27800109 |
| antibacterial activity of copaiba oil gel on dental biofilm. | amazonian biodiversity products that have been used for years in folk medicine, have emerged as feasible and promising alternatives for the inhibition of microorganisms in dental biofilm. copaiba oil, a phytotherapic agent widely used by the amazonian populations, is known for its antibacterial, anti-inflammatory, anesthetic, healing and antitumor medicinal properties. | 2016 | 27386004 |
| streptococcus constellatus tubo-ovarian abscess in a non-sexually active adolescent female. | tubo-ovarian abscess (toa) in non-sexually active female adolescents is a rare presentation to the pediatric emergency department. in the following case, bilateral toa secondary to streptococcus constellatus was diagnosed in a 13-year-old virginal female. the patient was seen 4 months before presentation for interventional radiology-guided drainage and antibiotic treatment for an intra-abdominal abscess due to suspected appendiceal rupture. exploratory laparotomy on the most recent presentation ... | 2016 | 27261953 |
| a case of odontogenic infection by streptococcus constellatus leading to systemic infection in a cogan's syndrome patient. | odontogenic infection in immunocompromised patients tends to extend systemically beyond the oral cavity. our case report presents a patient with sepsis due to a streptococcus constellatus (s. constellatus) odontogenic infection in a 64-year-old-immunocompromised woman with cogan's syndrome. she had been suffering from chronic mandibular osteomyelitis which was thought to have been caused by dental caries and/or chronic periodontitis with furcation involvement of the left mandibular first molar. ... | 2014 | 25506439 |
| a severe case of lemierre syndrome with streptococcus constellatus infection. | a 76-year-old japanese male presenting with high fever, headache, and disturbance of consciousness was hospitalized. contrast computed tomography revealed thrombophlebitis in the internal jugular vein and abscesses in the posterior neck region, pharynx, and pterygoid muscle. streptococcus constellatus infection was confirmed by culture of blood samples, and the patient was diagnosed with lemierre syndrome. in addition to the administration of antibiotics and anticoagulants, abscess drainage was ... | 2014 | 25410567 |
| subperiosteal inflammatory pseudotumor mimicking primary malignant bone tumor: a case report. | we report a case of igg4-positive inflammatory pseudotumor mimicking malignant bone tumor. biopsy revealed no tumor cells. surgical excision was performed and an abscess developing beneath the periosteum was observed with streptococcus constellatus. preoperative serum igg4 value of 120 mg/dl normalized postoperatively to 80.6 mg/dl. it was difficult to distinguish inflammatory pseudotumor from sarcoma because it developed under the periosteum. in such cases, it is important to measure blood igg4 ... | 2017 | 25381728 |
| antibiotic susceptibility of periodontal streptococcus constellatus and streptococcus intermedius clinical isolates. | streptococcus constellatus and streptococcus intermedius in subgingival dental plaque biofilms may contribute to forms of periodontitis that resist treatment with conventional mechanical root debridement/surgical procedures and may additionally participate in some extraoral infections. because systemic antibiotics are often used in these clinical situations, and little is known of the antibiotic susceptibility of subgingival isolates of these two bacterial species, this study determined the in v ... | 2014 | 25102269 |
| streptococcus constellatus community acquired pneumonia with subsequent isolated pulmonic valve endocarditis and abscess formation in a structurally normal heart. | pulmonic valve infective endocarditis in isolation is a rare clinical entity. the formation of an abscess in the right ventricular outflow tract as a consequence of vegetations affecting the pulmonic valve in a structurally normal heart is extremely rare and has not been reported. we report a case of isolated pulmonic valve endocarditis complicated by a regional abscess formed within the right ventricular outflow tract caused by streptococcus constellatus (s. constellatus), a member of the strep ... | 2014 | 25031801 |
| [a case report of gastrointestinal stromal tumor of the small intestine presenting with liver abscesses caused by streptococcus constellatus]. | a 49-year-old woman visited a local hospital in october 2007 with complaint of fever and melena. abdominal ultrasonography and abdominal computed tomography revealed an irregular mass in the lower abdomen, together with multiple masses in the liver. she was admitted because of anemia, and the high fever was determined to be an inflammatory response. blood tests revealed elevated biliary enzyme levels. percutaneous biopsy of the liver mass was performed, which revealed liver abscesses caused by s ... | 2014 | 24998728 |
| [fatal bone marrow necrosis and fat embolism following sepsis in a patient with acute lymphoblastic leukemia after consolidation chemotherapy]. | we report a 58-year-old japanese man with acute lymphoblastic leukemia. on the seventh day of his second course of consolidation therapy, he developed herpes zoster, and on the 17th day, he developed a high fever, dyspnea, and lapsed into a coma. streptococcus constellatus was isolated from blood culture. despite intensive therapy, multiple organ failure progressed rapidly, and he died on the 19th day. pathological examination of autopsy specimens revealed bone marrow necrosis and fat embolism i ... | 2014 | 24598195 |
| pulmonary artery pseudoaneurysm caused by streptococcus constellatus. | we report a rare case of mycotic pulmonary artery pseudoaneurysm (pap) secondary to a lung abscess due to streptococcus constellatus. pap was confirmed by the pathological findings of the pseudoaneurysm, the presence of bacteria, and the microbiological analysis. pap is uncommon, but it is important to recognize this condition because pap can lead to fatal hemoptysis. | 2013 | 24128874 |
| generalized peritonitis secondary to spontaneous perforation of pyometra in a 63-year-old patient. | spontaneous perforation of pyometra resulting in generalized diffuse peritonitis is extremely uncommon. herein, we report the case of a 63-year-old woman who presented to emergency department with a 2-day history of severe diffuse abdominal pain, high-grade fever, nausea, and vomiting. acute abdomen series was done, and upright plain chest radiograph showed free air under diaphragm. a noncontrast-enhanced computed tomography scan showed a significantly distended fluid-filled uterus measuring 10 ... | 2013 | 24073347 |
| a case of prosthetic valve endocarditis caused by streptococcus constellatus as a rare agent of endocarditis. | we present a case of prosthetic valve endocarditis, which was caused by a rare etiological agent, streptococcus constellatus. in our case, transesophageal echocardiography showed a large and broad abscess formation throughout the patient's aortic prosthetic valve ring and left atrium. despite specific intravenous antibiotic therapy, the infection was uncontrollable, and the patient underwent surgical treatment. the pathogen rarely causes endocarditis, but it is known to have a strong potential t ... | 2016 | 23831301 |
| a case of spontaneous abscess of the corpus cavernosum. | spontaneous abscess of the corpus cavernosum is an extremely rare presentation. this is the first documented case of corpus cavernosal abscess caused exclusively by organisms from the streptococcus milleri group, which have previously been described as being associated with abscess formation. this report outlines the case of a 56-year-old alcoholic male with no risk factors who presented with an 8-day history of penile pain, swelling and sepsis. a diagnosis of abscess of the right corpus caverno ... | 2013 | 23506057 |
| bilateral foveal cysts secondary to streptococcus constellatus endocarditis. | infective endocarditis can be acute or subacute, depending on the virulence of the causative organism. it can also cause loss of vision by a variety of mechanisms, ranging from embolic retinal artery occlusion to endogenous endophthalmitis. we illustrate the first report of foveal cyst formation secondary to infective endocarditis. a 53-year-old man presented to his general practitioner with a variety of constitutional symptoms, but initial laboratory and imaging investigations revealed only mil ... | 2013 | 23124195 |
| streptococcus constellatus lymphadenitis in chronic granulomatous disease. | | 2013 | 23076601 |
| [liver abscess due to streptococcus constellatus]. | | 2013 | 22796056 |
| ecomment. mitral and aortic valve endocarditis caused by streptococcus constellatus. | | 2012 | 22589356 |
| mitral and aortic valve endocarditis caused by a rare pathogen: streptococcus constellatus. | streptococcus constellatus endocarditis is associated with systemic embolism and frequently with a poor prognosis. we describe the first case reported in the literature of infective endocarditis by penicillin-resistant s. constellatus causing both mitral and aortic valve regurgitation, treated successfully with double-valve replacement. | 2012 | 22374286 |
| how to become a killer, or is it all accidental? virulence strategies in oral streptococci. | streptococci are a diverse group of gram-positive microorganisms sharing common virulence traits and similar strategies to escape the oral niche and establish an infection in other parts of the host organism. invasive infection with oral streptococci is "a perfect storm" that requires the concerted action of multiple biotic and abiotic factors. our understanding of streptococcal pathogenicity and infectivity should probably be less mechanistic and driven not only by the identification of novel v ... | 2017 | 28727895 |
| gas-containing cervical epidural abscess accompanying bacterial meningitis in an adult. | gas-containing spinal epidural abscesses are uncommon. moreover, acute spinal epidural abscesses rarely complicate bacterial meningitis in adults. here, we report a rare case of a gas-containing cervical epidural abscess accompanying bacterial meningitis. in spite of aggressive fluid and continuous antibiotic therapy after the isolation of streptococcus anginosus and streptococcus constellatus in the cerebrospinal fluid cultures, the patient showed remaining motor dysfunction and bladder involve ... | 2017 | 28407706 |
| streptococcus constellatus causing multiple liver abscesses: an elusive pathogen. | | 2017 | 28737114 |
| infections associated with streptococcus constellatus in children. | streptococcus constellatus is a viridans streptococcus belonging to the anginosus group. it was associated with abscesses in 37 children, 80% of whom had acute appendicitis with perforation and abscess formation in 50%. none of the children was younger than 3 years of age. | 2017 | 28640003 |
| odontogenic orbital cellulitis associated with cavernous sinus thrombosis and pulmonary embolism: a case report. | this case illustrates the importance of prompt assessment and treatment of orbital cellulitis. in fact the ocular signs and symptoms may be associated with systemic complications which should be investigated and identified as soon as possible to avoid a poor prognosis. | 2017 | 28629401 |