Publications

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discrimination of the effects of three cardiac ion channel blockers using ecg biomarkers and arrhythmia incidence in st. kitts green monkeys (chlorocebus sabaeus). 202031963047
synergistic effects of cisplatin-caffeic acid induces apoptosis in human cervical cancer cells via the mitochondrial pathways.cervical cancer (cxca) is a major health problem globally and is associated with the presence of human papillomavirus infection. cisplatin (cddp) is a platinum-based chemotherapeutic agent. owing to its side effects and drug-resistance, novel anticancer agents with lower toxicity, including caffeic acid (cfc), are of interest. however, the effects of cddp and cfc in combination are, to the best of our knowledge, uninvestigated. the present study investigated the effectiveness of cddp and cfc in ...201829731891
effects of prenatal alcohol exposure on the visual system of monkeys measured at different stages of development.fetal alcohol spectrum disorder (fasd) is a developmental disease characterized by behavioral problems and physical defects including malformations of the eye and associated optical defects. how these malformations affect retinal functioning is not well known, although animal models have suggested that scotopic vision is particularly deficient. age is also known to affect scotopic vision. here, we determined the combined effects of age and fetal alcohol exposure (fae) on retinal function using f ...201729242902
in vitro activity of human recombinant alpha-2b interferon against sars-cov-2 virus.the pandemic spread of a new coronavirus infection, covid-19, has caused a global emergency and attracted the attention of public health professionals and the population of all countries. a significant increase in the number of new cases of sars-cov-2 infection demonstrates the urgency of finding drugs effective against this pathogen.the aim of this work was to evaluate the in vitro antiviral efficacy of human recombinant alpha-2b interferon (ifn-α2b) against sars-cov-2 virus.202133993682
time-course transcriptome analysis of host cell response to poxvirus infection using a dual long-read sequencing approach.in this study, we applied two long-read sequencing (lrs) approaches, including single-molecule real-time and nanopore-based sequencing methods to investigate the time-lapse transcriptome patterns of host gene expression as a response to vaccinia virus infection. transcriptomes determined using short-read sequencing approaches are incomplete because these platforms are inefficient or fail to distinguish between polycistronic rnas, transcript isoforms, transcriptional start sites, as well as trans ...202134167576
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