| molecular cloning, characterization and comparison of bile salt hydrolases from lactobacillus johnsonii pf01. | to clone, characterize and compare the bile salt hydrolase (bsh) genes of lactobacillus johnsonii pf01. | 2013 | 23035872 |
| probiotics in the management of inflammatory bowel disease: a systematic review of intervention studies in adult patients. | mounting evidence suggests an important role for the intestinal microbiota in the chronic mucosal inflammation that occurs in inflammatory bowel disease (ibd), and novel molecular approaches have further identified a dysbiosis in these patients. several mechanisms of action of probiotic products that may interfere with possible aetiological factors in ibd have been postulated. | 2012 | 22512365 |
| characteristics of lactobacillus and gardnerella vaginalis from women with or without bacterial vaginosis and their relationships in gnotobiotic mice. | the objectives of the present study were to evaluate in vitro the production of antagonistic compounds against gardnerella vaginalis by lactobacillus strains isolated from women with or without bacterial vaginosis (bv), and to select one of the better lactobacillus producers of such a substance to be tested in vivo using a gnotobiotic animal model challenged with one of the more sensitive g. vaginalis isolates. a total of 24 isolates from women with and without bv were identified as g. vaginalis ... | 2012 | 22539000 |
| deconjugated bile salts produced by extracellular bile-salt hydrolase-like activities from the probiotic lactobacillus johnsonii la1 inhibit giardia duodenalis in vitro growth. | giardiasis, currently considered a neglected disease, is caused by the intestinal protozoan parasite giardia duodenalis and is widely spread in human as well as domestic and wild animals. the lack of appropriate medications and the spread of resistant parasite strains urgently call for the development of novel therapeutic strategies. host microbiota or certain probiotic strains have the capacity to provide some protection against giardiasis. by combining biological and biochemical approaches, we ... | 2016 | 27729900 |
| analysis of the microbial ecology between helicobacter pylori and the gastric microbiota of mongolian gerbils. | animal models are essential for in vivo analysis of helicobacter-related diseases. mongolian gerbils are used frequently to study helicobacter pylori-induced gastritis and its consequences. the presence of some gastric microbiota with a suppressive effect on h. pylori suggests inhibitory gastric bacteria against h. pylori infection. the aim of the present study was to analyse the microbial ecology between h. pylori and the gastric microbiota of mongolian gerbils. gastric mucosa samples of h. pyl ... | 2014 | 24164959 |
| eradication of helicobacter pylori infection by the probiotic strains lactobacillus johnsonii mh-68 and l. salivarius ssp. salicinius ap-32. | the current therapy for helicobacter pylori infection includes antimicrobial agents and proton pump inhibitors. we have examined the ability of lactobacillus spp. to inhibit h. pylori infection. | 2012 | 23067294 |
| reduction of overall helicobacter pylori colonization levels in the stomach of mongolian gerbil by lactobacillus johnsonii la1 (lc1) and its in vitro activities against h. pylori motility and adherence. | the effects of lactobacillus johnsonii la1 (lc1) on helicobacter pylori colonization in the stomach were investigated. h. pylori colonization and gastritis in lc1-inoculated mongolian gerbils were significantly less intense than those in the control animals. lc1 culture supernatant (>10-kda fraction) inhibited h. pylori motility and induced bacterial aggregation in human gastric epithelial cells, suggesting the potential of clinical use of lc1 product. | 2012 | 22484956 |
| peptide extracts from cultures of certain lactobacilli inhibit helicobacter pylori. | helicobacter pylori inhibition by probiotic lactobacilli has been observed in vitro and in vivo. carefully selected probiotic lactobacillus strains could therefore play an important role in the treatment of h. pylori infection and eradication. however, the underlying mechanism for this inhibition is not clear. the aim of this study was to examine if peptide extracts, containing bacteriocins or other antibacterial peptides, from six lactobacillus cultures (lactobacillus acidophilus la1, lactobaci ... | 2010 | 26780898 |
| probiotic potential of a lactobacillus bacterium of canine faecal-origin and its impact on select gut health indices and immune response of dogs. | the objective of the present study was to develop a probiotic of canine-origin for its potential application in pet nutrition. accordingly, 32 lactic acid bacteria (lab) strains were isolated from faeces of dogs, out of which 9 strains were short-listed for further in vitro testing based on the aggregation time and cell surface hydrophobicity. the results of acid-, bile- and phenol-tolerance tests indicated that out of the nine, isolate cpro23 was having better resistance to these adverse condit ... | 2017 | 28188477 |
| improved bioavailability of dietary phenolic acids in whole grain barley and oat groat following fermentation with probiotic lactobacillus acidophilus , lactobacillus johnsonii , and lactobacillus reuteri. | the aim of this study was to improve the bioavailability of the dietary phenolic acids in flours from whole grain barley and oat groat following fermentation with lactic acid bacteria (lab) exhibiting high feruloyl esterase activity (fae). the highest increase of free phenolic acids was observed after fermentation with three probiotic strains, lactobacillus johnsonii la1, lactobacillus reuteri sd2112, and lactobacillus acidophilus la-5, with maximum increases from 2.55 to 69.91 μg g(-1) dm and f ... | 2012 | 22676388 |
| identification of lactobacillus strains of goose origin using maldi-tof mass spectrometry and 16s-23s rdna intergenic spacer pcr analysis. | the objective of our study was to identify lactobacillus sp. strains of goose origin using maldi-tof mass spectrometry, its-pcr and its-pcr/rflp. all three techniques proved to be valuable tools for identification of avian lactobacilli and produced comparable classification results. lactobacillus strains were isolated from 100% of geese aged 3 weeks to 4 years, but from only 25% of chicks aged 1-10 days. among the 104 strains isolated, we distinguished 14 lactobacillus species. the dominant spec ... | 2014 | 24607713 |
| identification and characterization of intestinal lactobacilli strains capable of degrading immunotoxic peptides present in gluten. | identify and characterize bacteria from the proximal gastrointestinal tract of pigs capable of degrading immunogenic gluten peptides. | 2015 | 25376327 |
| intestinal concentrations of free and encapsulated dietary medium-chain fatty acids and effects on gastric microbial ecology and bacterial metabolic products in the digestive tract of piglets. | the influence of low dietary levels of free and encapsulated medium-chain fatty acids on their concentrations in the digesta, the gastric microbial ecology and bacterial metabolic products in the gastrointestinal tract (git) in weaned piglets was studied. starting after weaning, 36 piglets were fed a diet without (control) or with medium-chain fatty acids uncoated (mcfa) or coated with vegetable fat and lecithin (mcfac). after 4 weeks, the animals were killed, and digesta from the stomach and di ... | 2012 | 22397093 |
| effects of intraduodenal injection of lactobacillus brevis sbc8803 on autonomic neurotransmission and appetite in rodents. | lactobacilli provide several health benefits to mammals, including humans. we previously observed that in rats, intraduodenal injection of lactobacillus johnsonii la1 elevated efferent gastric vagal nerve activity (efferent-gvna), while lactobacillus paracasei st11 suppressed efferent-gvna, and thereby increased or decreased food intake. to determine the function of lactobacillus brevis (sbc8803), its effect on food intake was examined by providing food containing heat-killed sbc8803 to mice. we ... | 2013 | 23391754 |
| transformation kinetics of fermented milk using lactobacillus casei (lc1) and streptococcus thermophilus: comparison of results with other inocula. | probiotic-based starter cultures are generally used to produce fermented milks with improved characteristics in the final product. in this study, lactobacillus casei and streptococcus thermophilus (lc1-st) were used as the starter inoculum. the transformation kinetics and properties of the final product were compared with systems produced with other inocula. the lc1-st inoculum delayed the production of lactic acid from 40 to 70 min (depending on temperature and concentration) when compared to l ... | 2017 | 27821208 |
| human milk and mucosal lacto- and galacto-n-biose synthesis by transgalactosylation and their prebiotic potential in lactobacillus species. | lacto-n-biose (lnb) and galacto-n-biose (gnb) are major building blocks of free oligosaccharides and glycan moieties of glyco-complexes present in human milk and gastrointestinal mucosa. we have previously characterized the phospho-β-galactosidase gnbg from lactobacillus casei bl23 that is involved in the metabolism of lnb and gnb. gnbg has been used here in transglycosylation reactions, and it showed the production of lnb and gnb with n-acetylglucosamine and n-acetylgalactosamine as acceptors, ... | 2017 | 27714445 |
| lactobacillus gasseri requires peptides, not proteins or free amino acids, for growth in milk. | lactobacillus gasseri is a widespread commensal lactic acid bacterium inhabiting human mucosal niches and has many beneficial effects as a probiotic. however, l. gasseri is difficult to grow in milk, which hurts usability for the food industry. it had been previously reported that supplementation with yeast extract or proteose peptone, including peptides, enables l. gasseri to grow well in milk. in this study, our objective was to confirm peptide requirement of l. gasseri and evaluate efficacy o ... | 2015 | 25529420 |
| lactobacillus rodentium sp. nov., from the digestive tract of wild rodents. | three strains of regular, long, gram-stain-positive bacterial rods were isolated using tpy, m.r.s. and rogosa agar under anaerobic conditions from the digestive tract of wild mice (mus musculus). all 16s rrna gene sequences of these isolates were most similar to sequences of lactobacillus gasseri atcc 33323t and lactobacillus johnsonii atcc 33200t (97.3% and 97.2% sequence similarities, respectively). the novel strains shared 99.2-99.6% 16s rrna gene sequence similarities. type strains of l. gas ... | 2014 | 24478214 |
| characterization of the genome of the dairy lactobacillus helveticus bacteriophage {phi}aq113. | the complete genomic sequence of the dairy lactobacillus helveticus bacteriophage φaq113 was determined. phage φaq113 is a myoviridae bacteriophage with an isometric capsid and a contractile tail. the final assembled consensus sequence revealed a linear, circularly permuted, double-stranded dna genome with a size of 36,566 bp and a g+c content of 37%. fifty-six open reading frames (orfs) were predicted, and a putative function was assigned to approximately 90% of them. the φaq113 genome shows fu ... | 2013 | 23728811 |
| lactobacillus pasteurii sp. nov. and lactobacillus hominis sp. nov. | strains 1517(t) and 61d(t) were characterized by phenotypic and molecular taxonomic methods. these gram-positive lactic acid bacteria were homo-fermentative, facultatively anaerobic short rods. they were phylogenetically related to the genus lactobacillus according to 16s rrna gene sequence analysis, with 99 % similarity between strain 1517(t) and the type strain of lactobacillus gigeriorum, and 98.6, 98.5 and 98.4 % between strain 61d(t) and lactobacillus gasseri, lactobacillus taiwanensis and ... | 2013 | 22328611 |
| lactobacillus johnsonii supplementation attenuates respiratory viral infection via metabolic reprogramming and immune cell modulation. | regulation of respiratory mucosal immunity by microbial-derived metabolites has been a proposed mechanism that may provide airway protection. here we examine the effect of oral lactobacillus johnsonii supplementation on metabolic and immune response dynamics during respiratory syncytial virus (rsv) infection. l. johnsonii supplementation reduced airway t helper type 2 cytokines and dendritic cell (dc) function, increased regulatory t cells, and was associated with a reprogrammed circulating meta ... | 2017 | 28295020 |
| heat-killed lactobacillus salivarius and lactobacillus johnsonii reduce liver injury induced by alcohol in vitro and in vivo. | the aim of the present study was to determine whether lactobacillus salivarius (ls) and lactobacillus johnsonii (lj) prevent alcoholic liver damage in hepg2 cells and rat models of acute alcohol exposure. in this study, heat-killed ls and lj were screened from 50 lactobacillus strains induced by 100 mm alcohol in hepg2 cells. the severity of alcoholic liver injury was determined by measuring the levels of aspartate transaminase (ast), alanine transaminase (alt), gamma-glutamyl transferase (γ-gt) ... | 2016 | 27809254 |
| lactobacillus johnsonii glycolipids, their structure and immunoreactivity with sera from inflammatory bowel disease patients. | structural studies of the major glycolipids produced by two lactobacillus johnsonii (lj) strains, lj 151 isolated from intestinal tract of healthy mice and lj 142 isolated from mice with experimentally induced inflammatory bowel disease (ibd), were performed. two major glycolipids, gl1 and gl2, were present in lipid extracts from l. johnsonii 142 and 151 strains. glycolipid gl1 has been identified as β-d-glcp-(1→6)-α-d-galp-(1→2)-α-d-glcp-diglyceride and gl2 as α-d-galp-(1→2)-α-d-glcp-diglycerid ... | 2017 | 27766756 |
| genome sequence of lactobacillus johnsonii strain w1, isolated from mice. | lactobacillus johnsonii, a member of the gut lactobacilli, plays an important role in normal gut functioning. here, we report the draft genome sequence of l. johnsonii strain w1 isolated from icr mice. | 2016 | 27313302 |
| lactobacilli with probiotic potential in the prairie vole (microtus ochrogaster). | recent research suggests integration of the intestinal microbiota in gut-brain communication which could lead to new approaches to treat neurological disorders. the highly social prairie voles are an excellent model system to study the effects of environmental factors on social behavior. for future studies on the role of probiotics in ameliorating disorders with social withdrawal symptoms, we report the characterization of intestinal lactobacillus isolates with probiotic potential from voles. | 2015 | 26719773 |
| draft genome sequence of lactobacillus johnsonii strain 16, isolated from mice. | here, we report the genome sequence of lactobacillus johnsonii, a member of the gut lactobacilli. this draft genome of l. johnsonii strain 16 isolated from c57bl/6j mice enables the identification of bacterial genes responsible for host-specific gut persistence. | 2015 | 26450724 |
| epsa is an essential gene in exopolysaccharide production in lactobacillus johnsonii fi9785. | lactobacillus johnsonii fi9785 has an eps gene cluster which is required for the biosynthesis of homopolymeric exopolysaccharides (eps)-1 and heteropolymeric eps-2 as a capsular layer. the first gene of the cluster, epsa, is the putative transcriptional regulator. in this study we showed the crucial role of epsa in eps biosynthesis by demonstrating that deletion of epsa resulted in complete loss of both eps-1 and eps-2 on the cell surface. plasmid complementation of the epsa gene fully restored ... | 2016 | 26401596 |
| influence of housing characteristics on bacterial and fungal communities in homes of asthmatic children. | variations in home characteristics, such as moisture and occupancy, affect indoor microbial ecology as well as human exposure to microorganisms. our objective was to determine how indoor bacterial and fungal community structure and diversity are associated with the broader home environment and its occupants. next-generation dna sequencing was used to describe fungal and bacterial communities in house dust sampled from 198 homes of asthmatic children in southern new england. housing characteristi ... | 2016 | 25833176 |
| effect of lactobacillus johnsonii crl1647 on different parameters of honeybee colonies and bacterial populations of the bee gut. | lactobacillus johnsonii crl1647, isolated from the intestinal tract of a worker-bee in salta, argentina, was delivered to apis mellifera l. honey bee colonies according to two different administration schedules: 1×10(5) cfu/ml every 15 days (2011) or monthly (2012). the effect of each treatment on the bee-colony performance was monitored by measuring honey production, and the prevalence of varroasis and nosemosis. worker bees from each assay were randomly captured 3 days after administration and ... | 2015 | 25809216 |
| impact of the exopolysaccharide layer on biofilms, adhesion and resistance to stress in lactobacillus johnsonii fi9785. | the bacterial cell surface is a crucial factor in cell-cell and cell-host interactions. lactobacillus johnsonii fi9785 produces an exopolysaccharide (eps) layer whose quantity and composition is altered in mutants that harbour genetic changes in their eps gene clusters. we have assessed the effect of changes in eps production on cell surface characteristics that may affect the ability of l. johnsonii to colonise the poultry host and exclude pathogens. | 2015 | 25648083 |
| effects of a yeast-dried milk product in creep and phase-1 nursery diets on growth performance, circulating immunoglobulin a, and fecal microbiota of nursing and nursery pigs. | four experiments were conducted to evaluate effects of yeast-dried milk (ydm) product in creep and phase-1 nursery diets. in exp. 1, 24 parity-4 litters were allotted to 3 dietary treatments (8 litters/treatment) including no creep (nc), control creep (ctl), and experimental creep (ec; 10% ydm). creep diets were fed twice daily from d 7 after birth until weaning (23.6 ± 1.8 d). in exp. 2, 108 weaned pigs were selected based on mean bw of pigs from the respective treatments in exp. 1. for phase 1 ... | 2014 | 25184835 |
| complete genome sequences of lactobacillus johnsonii strain n6.2 and lactobacillus reuteri strain td1. | we report here the complete genome sequences of lactobacillus johnsonii strain n6.2, a homofermentative lactic acid intestinal bacterium, and lactobacillus reuteri strain td1, a heterofermentative lactic acid intestinal bacterium, both isolated from a type 1 diabetes-resistant rat model. | 2014 | 24812223 |
| preventing non-alcoholic fatty liver disease through lactobacillus johnsonii bs15 by attenuating inflammation and mitochondrial injury and improving gut environment in obese mice. | the increasing prevalence of obesity worldwide is associated with a parallel increase in non-alcoholic fatty liver disease (nafld). to investigate the effect of lactobacillus johnsonii bs15 on nafld, 120 male icr mice were randomly divided into four groups and administrated with bs15 (2 × 10(7) cfu/0.2 ml or 2 × 10(8) cfu/0.2 ml) or phosphate buffered saline (pbs) throughout a 17-week experimental period. the mice were fed with normal chow diet (ncd) 5 weeks before the experimental period. after ... | 2014 | 24811405 |
| house dust exposure mediates gut microbiome lactobacillus enrichment and airway immune defense against allergens and virus infection. | exposure to dogs in early infancy has been shown to reduce the risk of childhood allergic disease development, and dog ownership is associated with a distinct house dust microbial exposure. here, we demonstrate, using murine models, that exposure of mice to dog-associated house dust protects against ovalbumin or cockroach allergen-mediated airway pathology. protected animals exhibited significant reduction in the total number of airway t cells, down-regulation of th2-related airway responses, as ... | 2014 | 24344318 |
| prevention of polymorphic light eruption by oral administration of a nutritional supplement containing lycopene, β-carotene, and lactobacillus johnsonii: results from a randomized, placebo-controlled, double-blinded study. | polymorphic light eruption (ple) is the most common photodermatosis. little is known about the efficacy of systemic photoprotection provided by nutritional supplements in ple patients. | 2014 | 24283388 |
| effects of the organic acids produced by a lactic acid bacterium in apis mellifera colony development, nosema ceranae control and fumagillin efficiency. | the european honey bee apis mellifera is known to be affected by many parasites and pathogens that have great impact over the insect development. among parasites affecting bee health, nosema ceranae is one of the main biotic factors affecting colony populations. as honey bee populations decline, interest in pathogenic and mutualistic relationships between bees and microorganisms has increased. the main goal of the current study was to assess the effect of the oral administration of the metabolit ... | 2013 | 23978352 |
| intestinal bacteria modify lymphoma incidence and latency by affecting systemic inflammatory state, oxidative stress, and leukocyte genotoxicity. | ataxia-telangiectasia is a genetic disorder associated with high incidence of b-cell lymphoma. using an ataxia-telangiectasia mouse model, we compared lymphoma incidence in several isogenic mouse colonies harboring different bacterial communities, finding that intestinal microbiota are a major contributor to disease penetrance and latency, lifespan, molecular oxidative stress, and systemic leukocyte genotoxicity. high-throughput sequence analysis of rrna genes identified mucosa-associated bacter ... | 2013 | 23860718 |
| the structure and immunoreactivity of exopolysaccharide isolated from lactobacillus johnsonii strain 151. | the exopolysaccharide (eps) structure from lactobacillus johnsonii strain 151 isolated from the intestinal tract of mice was investigated. sugar and methylation analyses together with (1)h and (13)c nmr spectroscopy, including two-dimensional (1)h,(1)h cosy, tocsy, noesy, and (1)h,(13)c hsqc, hmbc experiments, revealed that the repeating unit of the eps is the linear pentasaccharide: →6)-α-d-galp-(1→6)-α-d-glcp-(1→3)-β-d-galf-(1→3)-α-d-glcp-(1→2)-β-d-galf-(1→ the immunoreactivity of two structur ... | 2013 | 23787056 |
| spontaneous mutation reveals influence of exopolysaccharide on lactobacillus johnsonii surface characteristics. | as a competitive exclusion agent, lactobacillus johnsonii fi9785 has been shown to prevent the colonization of selected pathogenic bacteria from the chicken gastrointestinal tract. during growth of the bacterium a rare but consistent emergence of an altered phenotype was noted, generating smooth colonies in contrast to the wild type rough form. a smooth colony variant was isolated and two-dimensional gel analysis of both strains revealed a protein spot with different migration properties in the ... | 2013 | 23544114 |
| oxygen relieves the co2 and acetate dependency of lactobacillus johnsonii ncc 533. | oxygen relieves the co2 and acetate dependency of lactobacillus johnsonii ncc 533. the probiotic lactobacillus johnsonii ncc 533 is relatively sensitive to oxidative stress; the presence of oxygen causes a lower biomass yield due to early growth stagnation. we show however that oxygen can also be beneficial to this organism as it relieves the requirement for acetate and co2 during growth. both on agar- and liquid-media, anaerobic growth of l. johnsonii ncc 533 requires co2 supplementation of the ... | 2013 | 23468944 |
| lactobacillus johnsonii inhibits indoleamine 2,3-dioxygenase and alters tryptophan metabolite levels in biobreeding rats. | in our previous work, we found that feeding lactobacillus johnsonii to biobreeding diabetes-prone (bbdp) rats decreased the incidence of diabetes development. the aim of this study was to investigate host pathways affected by l. johnsonii, with specific focus on the rate-limiting enzyme of tryptophan catabolism, indoleamine 2,3-dioxygenase (ido). suspensions of l. johnsonii or an equal volume of vehicle were orally administered to bbdp rats. tissue ido was investigated using quantitative rt-pcr ... | 2013 | 23303207 |
| proteomic and transcriptional analysis of lactobacillus johnsonii pf01 during bile salt exposure by itraq shotgun proteomics and quantitative rt-pcr. | lactobacillus johnsonii pf01 has been reported to be highly resistant to bile, a key property of probiotic microorganisms. here, we examine the nature of the bile-salt tolerance of l. johnsonii pf01. growth inhibition and surface morphology and physiology aberrations were observed after overnight exposure to bile stress. quantitative proteomic profiles using itraq-lc-ms/ms technology identified 8307 peptides from both untreated pf01 cells and those exposed to 0.1%, 0.2%, and 0.3% bile salts. som ... | 2013 | 23181408 |
| impact of chicory inclusion in a cereal-based diet on digestibility, organ size and faecal microbiota in growing pigs. | a total of 30 7-week-old pigs were used to evaluate the effects of chicory inclusion on digestibility, digestive organ size and faecal microbiota. five diets were formulated: a cereal-based control diet and four diets with inclusion of 80 and 160 g/kg chicory forage (cf80 and cf160), 80 g/kg chicory root (cr80) and a mix of 80 g/kg forage and 80 g/kg chicory root (cfr). generally, the pigs showed a high growth rate and feed intake, and no differences between the different diets were observed. th ... | 2012 | 23031467 |
| screening of probiotic lactobacilli for inhibition of shigella sonnei and the macromolecules involved in inhibition. | a total of 91 lactobacilli were screened for antimicrobial activity against shigella sonnei. agar-well assay showed that 16 lactobacilli displayed strong antibacterial activity against s. sonnei. the nature of these antimicrobial agents were investigated and shown to be dependent on their production of organic acids. adhesion tests showed that 6 lactobacilli demonstrated good adherence to ht-29 cells, of these lactobacillus johnsonii f0421 were selected for acid and bile salt tolerance propertie ... | 2012 | 22967793 |
| iga production in the large intestine is modulated by a different mechanism than in the small intestine: bacteroides acidifaciens promotes iga production in the large intestine by inducing germinal center formation and increasing the number of iga+ b cells. | it has been demonstrated that intestinal commensal bacteria induce immunoglobulin (ig) a production by promoting the development of gut-associated lymphoid tissues in the small intestine. however, the precise mechanism whereby these bacteria modulate iga production in the large intestine, which harbors the majority of intestinal commensals, is poorly understood. in addition, it is not known which commensal bacteria induce iga production in the small intestine and which induce production in the l ... | 2013 | 22940255 |
| hydrolysis of chicoric and caftaric acids with esterases and lactobacillus johnsonii in vitro and in a gastrointestinal model. | chicoric acid (cha) and caftaric acid (cafa) were identified as bioactive components of chicory and have been ascribed a number of health benefits. this study investigated the hydrolysis of cha and cafa with enzymes and a probiotic bacterium lactobacillus johnsonii (la1). esterase from aspergillus japonicus (24 u/mg) hydrolyzed 100% of cha (5 mm) and cafa (5 mm) after 3 h, at ph 7.0 and 37 °c. under the same reaction conditions, 100% hydrolysis of cha and cafa was achieved with a spray-dried pre ... | 2012 | 22920606 |
| lactobacillus johnsonii la1 without antioxidants does not decrease bacterial translocation in rats with carbon tetrachloride-induced cirrhosis. | | 2012 | 22824820 |
| a trial of adding lactobacillus johnsonii em1 to levocetirizine for treatment of perennial allergic rhinitis in children aged 7-12 years. | supplementary consumption of probiotics may temporarily alter the intestinal microflora of infants and children, thereby preventing and treating allergic disorders. | 2012 | 22513081 |
| lactobacillus and pediococcus species richness and relative abundance in the vagina of rhesus monkeys (macaca mulatta). | the rhesus monkey is an important animal model to study human vaginal health to which lactic acid bacteria play a significant role. however, the vaginal lactic acid bacterial species richness and relative abundance in rhesus monkeys is largely unknown. | 2012 | 22429090 |
| persistence of orally administered lactobacillus strains in the gut of infant mice. | the present study tested the persistence of orally administered bacteria in the gut of suckling mice. we used three bacterial strains: one strain of lactobacillus johnsonii (designated strain ms1) that was previously isolated from the mouse stomach, and two strains of l. plantarum, (strain no. 14 and jcm 1149(t)). we detected l. johnsonii ms1, but neither strain of l. plantarum, in the gut 7 days after administration when the organisms were administered on days 0, 1, 3 or 7 of neonatal life. non ... | 2012 | 24936354 |
| electrophysiological analysis of the mechanism of autonomic action by lactobacilli. | autonomic nerves, consisting of both sympathetic and parasympathetic nerves, regulate various bodily functions such as blood pressure, body temperature, glucose metabolism, energy metabolism, and digestion. our studies in rats and mice have demonstrated that food, flavor, and music affect physiological phenomena via changes in autonomic neurotransmissions. intestinal injection of lactobacillus johnsonii la1 (ncc533) suppressed sympathetic nerves that innervate the adrenal gland and kidney of ure ... | 2011 | 25045315 |
| differential effect of lactobacillus johnsonii bfe 6128 on expression of genes related to tlr pathways and innate immunity in intestinal epithelial cells. | probiotics have been shown to enhance immune defenses, but their mechanisms of action are only partially understood. we investigated the modulation of signal pathways involved in innate immunity in enterocytes by lactobacillus johnsonii bfe 6128 isolated from 'kule naoto', a maasai traditional fermented milk product. this lactobacillus sensitized ht29 intestinal epithelial cells toward recognition of salmonella enterica serovar typhimurium by increasing the il-8 levels released after challenge w ... | 2010 | 26781315 |
| control of lupus nephritis by changes of gut microbiota. | systemic lupus erythematosus, characterized by persistent inflammation, is a complex autoimmune disorder with no known cure. immunosuppressants used in treatment put patients at a higher risk of infections. new knowledge of disease modulators, such as symbiotic bacteria, can enable fine-tuning of parts of the immune system, rather than suppressing it altogether. | 2017 | 28697806 |
| to add or not to add probiotics to infant formulae? an updated systematic review. | we updated evidence on the effects of the administration of probiotic-supplemented infant formulae (if) compared with unsupplemented if. five databases were searched up to september 2016 for randomised controlled trials. twenty publications were identified, including five new rcts. supplementation of if with bifidobacterium lactis bb12, either alone or with streptococcus thermophilus, had no effect on growth, respiratory illness, antibiotic use, stool frequency or consistency. however, there was ... | 2017 | 28856907 |
| lactobacillus johnsonii ameliorates intestinal, extra-intestinal and systemic pro-inflammatory immune responses following murine campylobacter jejuni infection. | campylobacter jejuni infections are progressively increasing worldwide. probiotic treatment might open novel therapeutic or even prophylactic approaches to combat campylobacteriosis. in the present study secondary abiotic mice were generated by broad-spectrum antibiotic treatment and perorally reassociated with a commensal murine lactobacillus johnsonii strain either 14 days before (i.e. prophylactic regimen) or 7 days after (i.e. therapeutic regimen) peroral c. jejuni strain 81-176 infection. f ... | 2017 | 28522817 |
| perfluorooctane sulfonate affects intestinal immunity against bacterial infection. | perfluorooctane sulfonate (pfos) is an environmental contaminant that has been manufactured to be used as surfactants and repellents in industry. due to long half-life for clearance and degradation, pfos is accumulative in human body and has potential threat to human health. previous studies have shown the development and function of immune cells can be affected by pfos. although pfos has a high chance of being absorbed through the oral route, whether and how pfos affects immune cells in the gut ... | 2017 | 28701769 |
| supplemental thymol and carvacrol increases ileum lactobacillus population and reduces effect of necrotic enteritis caused by clostridium perfringes in chickens. | necrotic enteritis (ne) caused by clostridium perfringens is one of the most detrimental infectious diseases in poultry. this study examined the effect of blends of essential oils (beos) (25% thymol and 25% carvacrol) on ne and bacterial dynamics and functions in chicks challenged with c. perfringens. chicks were assigned to a control diet and beos diet (control diet + 120 mg/kg beos), were challenged with c. perfringens from days 14 to 20 and were killed on day 21 for assessment. supplementatio ... | 2017 | 28779076 |
| gastrointestinal inflammation by gut microbiota disturbance induces memory impairment in mice. | in this study, we tested our hypothesis regarding mechanistic cross-talk between gastrointestinal inflammation and memory loss in a mouse model. intrarectal injection of the colitis inducer 2,4,6-trinitrobenzenesulfonic acid (tnbs) in mice caused colitis via activation of nuclear factor (nf)-κb and increase in membrane permeability. tnbs treatment increased fecal and blood levels of lipopolysaccharide (lps) and the number of enterobacteriaceae, particularly escherichia coli (ec), in the gut micr ... | 2017 | 28612842 |
| anti-helicobacter pylori activity of non-living, heat-killed form of lactobacilli including lactobacillus johnsonii no.1088. | some strains of lactic acid bacteria are reported to inhibit the growth of helicobacter pylori and proposed to be useful to support so-called triple therapy for h. pylori. although most strains must be alive to exert their anti-h. pylori activity, some lactobacilli strains are effective even when dead. one possible underlying mechanism of such an activity of non-living lactobacilli is reportedly co-aggregation with h. pylori. in this study, we found that a non-living heat-killed form of lactobac ... | 2017 | 28505287 |
| selection of potential probiotic lactobacillus with inhibitory activity against salmonella and fecal coliform bacteria. | three hundred and sixty presumptive lactic acid bacteria (lab) isolated from pregnant sows, newborn, suckling, and weaned piglets were preliminarily screened for anti-salmonella activity. fifty-eight isolates consisting of lactobacillus reuteri (n = 32), lactobacillus salivarius (n = 10), lactobacillus mucosae (n = 8), lactobacillus johnsonii (n = 5), and lactobacillus crispatus (n = 3) were selected and further characterized for probiotic properties including production of antimicrobial substan ... | 2017 | 28712023 |
| effect of a lotion containing the heat-treated probiotic strain lactobacillus johnsonii ncc 533 on staphylococcus aureus colonization in atopic dermatitis. | staphylococcus aureus dominates the skin microbiota in patients with atopic dermatitis (ad), with bacterial loads correlating with disease severity. the aim of this exploratory study was to investigate the effect of a cosmetic lotion containing heat-treated lactobacillus johnsonii ncc 533 (ht la1) on s. aureus colonization in ad patients. | 2017 | 28721083 |
| extending viability of lactobacillus plantarum and lactobacillus johnsonii by microencapsulation in alginate microgels. | to investigate whether microencapsulation of lactobacillus in alginate microbeads will lead to increased longevity during refrigerated storage or simulated digestion. | 2017 | 28683582 |
| lactobacillus johnsonii n6.2 modulates the host immune responses: a double-blind, randomized trial in healthy adults. | lactobacillus johnsonii n6.2 mitigates the onset of type 1 diabetes (t1d) in biobreeding diabetes-prone rats, in part, through changes in kynurenine:tryptophan (k:t) ratios. the goal of this pilot study was to determine the safety, tolerance, and general immunological response of l. johnsonii n6.2 in healthy subjects. a double-blind, randomized clinical trial in 42 healthy individuals with no known risk factors for t1d was undertaken to evaluate subject responses to the consumption of l. johnson ... | 2017 | 28659913 |
| live probiotic lactobacillus johnsonii bs15 promotes growth performance and lowers fat deposition by improving lipid metabolism, intestinal development, and gut microflora in broilers. | numerous studies have focused on the beneficial effects of probiotics in animals. even so, additional information should be obtained about the mechanisms by which a useful probiotic strain successfully exerts such beneficial effects. in this study, we evaluated the effect of the dietary supplementation of both live and disrupted lactobacillus johnsonii (lj) strain bs15 in broilers at different ages. specifically, growth performance, lipid metabolism, gut microbiota, intestinal development, and d ... | 2017 | 28659893 |
| preventing subclinical necrotic enteritis through lactobacillus johnsonii bs15 by ameliorating lipid metabolism and intestinal microflora in broiler chickens. | increasing studies have focused on the beneficial effects of lactobacillus johnsonii in certain diseases. here, we studied the prevention ability of a probiotic strain, l. johnsonii bs15 on subclinical necrotic enteritis (sne), and its underlying mechanism. 180 male cobb 500 chicks were randomly allotted into three groups and administrated with bs15 (1 × 10(6) cfu/g) or man rogosa sharpe liquid medium throughout a 28-day experimental period. with the exception of the normal group, sne infection ... | 2017 | 28655217 |