| dirofilaria repens: a dog parasite presenting as a paranasal subcutaneous nodule. | | 2006 | 16650184 |
| natural vectors of dirofilariasis in rural and urban areas of the tuscan region, central italy. | entomological investigations by means of dog- and human-baited traps were carried out in summers 2000-2002 in urban and rural areas of the tuscan region in central italy. the aim of the study was to define the mosquito species involved in the transmission of dirofilaria nematodes and to assess the risk that their presence might represent for animal and human health. nocturnal fieldwork on host-seeking activity and feeding preferences was followed by microscopic identification of the mosquito spe ... | 2006 | 16739418 |
| detection of dirofilaria (nochtiella) repens dna by polymerase chain reaction in embedded paraffin tissues from two human pulmonary locations. | we here report two new cases of human pulmonary dirofilariasis in men aged 62 and 64 from northern and central italy, respectively. both were asymptomatic and the infections were discovered incidentally when chest radiographs taken for another reason revealed the presence of a coin lesion. the initial clinical diagnosis was oriented towards a lung tumour, and an excisional lung biopsy after thoracotomy was necessary for the final diagnosis. pathologically, the lesion consisted of a roundish subp ... | 2006 | 16907864 |
| dirofilaria repens infection case in hungary: a case report. | a 51-year-old female developed urticarial lesions of her right forearm which progressed into transient edema and subcutaneous swelling. later a small infiltrated subcutaneous nodule also appeared and was removed in toto. histopathological examination revealed the presence of dirofilaria repens. this worm is the cause of an endemic zoonosis in the mediterranean area. in the past decade many cases have been reported worldwide, but the condition appears rare in hungary and skin findings have not be ... | 2006 | 17176413 |
| subconjunctival infection with dirofilaria repens. | | 2002 | 17259773 |
| human subcutaneous dirofilariasis, russia. | we report 14 cases of human subcutaneous dirofilariasis caused by dirofilaria repens, diagnosed from february 2003 through july 2004, in patients from rostovon-don, russia. serologic analysis showed evidence of high risk of exposure to d. repens. surveillance studies on prevalence and prevention effectiveness of canine infection are needed to control this emerging zoonosis. | 2007 | 17370533 |
| [subcutaneous dirofilaria repens dirofilariasis in the sfax region (tunisia)]. | subcutaneous dirofilariasis is zoonotic infection caused by dirofilaria repens, the principal reservoir of which is the dog. clinical expression is usually benign but problems of differential diagnosis are present in some cases. we report the first case of dirofilariasis diagnosed in our area (sfax, southern tunisia). | 2007 | 17384544 |
| [human dirofilariasis: 3 cases in the south of france]. | dirofilariasis is a zoonosis usually found in dogs and cats. it is rare in humans, who are dead-end hosts for the parasite. | 2007 | 17398064 |
| molecular survey of dirofilaria immitis and dirofilaria repens by direct pcr for wild caught mosquitoes in the republic of korea. | adult mosquito collections using new jersey light traps and black-hole light traps were conducted to determine the potential vectors and the relative mosquito infection rates of dirofilaria immitis and dirofilaria repens in gyeonggi and gangwon provinces, republic of korea, 2005. dirofilaria spp. were confirmed by polymerase chain reaction (pcr) using species-specific primers for d. immitis and d. repens. minimum field infection rates (mfir) [mfir = (number infected pools/total number of mosquit ... | 2007 | 17644255 |
| a case of orbital dirofilariasis in northern turkey. | a 29-year-old male patient presented with complaints of a localized mass behind his right lower eyelid that had been present for the last 6 months. ophthalmologic examination was completely normal except for a 2 cm x 2 cm painless mass localized on the inferior orbital rim behind the right lower eyelid. an excisional biopsy was planned, and an anterior orbitotomy was performed by a lateral canthotomy and inferior cantholysis. premature rupture of the cyst occurred during dissection, disclosing a ... | 2007 | 17667116 |
| dirofilaria repens diagnosed by the presence of microfilariae in fine needle aspirates: a case report. | dirofilariasis due to dirofilaria repens with viable microfilariae outside the worm have not been reported before. | 2007 | 17718123 |
| [human subcutaneous dirofilariosis due to dirofilaria repens. a case diagnosed in strasbourg, france]. | we report a case of human dirofilariosis in a 35 year-old man living in alsace (north-east france), who presented a subcutaneous nodule of the left cheek, strongly simulating an epidermic cyst. surgical excision and histopathological examination unexpectedly established the diagnosis by the presence of nematode worm sections identified as dirofilaria (nochtiella) repens. this patient living in a rural area of strasbourg spent one week in toulon, southern france. this new observation of cutaneous ... | 2007 | 17982856 |
| aedes albopictus and culex pipiens implicated as natural vectors of dirofilaria repens in central italy. | to identify the natural vectors of dirofilaria repens railliet et henry, entomological samplings were carried out in four sites within the lazio region, foci of canine subcutaneous dirofilariasis. collections were made in 2002-2003 by means of dog-baited and miniature centers for disease control and prevention traps as well as on humans. microscopy identified 1576 attracted mosquito females as belonging to six species, but molecular diagnostics detected filarial dna only in culex pipiens l. and ... | 2007 | 18047207 |
| periorbital subcutaneous tumor-like lesion due to dirofilaria repens. | dirofilariasis is a zoonotic infection, which is occasionally seen in humans and rarely found as a subcutaneous orbital swelling. the authors report a case of a 62-year-old woman presented with a 3-month history of a right periorbital subcutaneous nodule. treatment with antibiotics and corticosteroids was not satisfactory. magnetic resonance imaging analysis showed a nodule with a central colliquative area. the lesion displaced the eyeball superiorly but did not affect the intraorbital muscles. ... | 2008 | 18203797 |
| human dirofilariosis in hungary: an emerging zoonosis in central europe. | in the temperate regions of europe, mainly italy, france, greece, and in recent years hungary, a specific filarioid worm, dirofilaria (nochtiella) repens, a parasite of dogs, cats and some other carnivores, transmitted by mosquitoes, has occasionally been contracted, causing dirofilariosis in humans. we report a case of dirofilariosis and review all previously observed cases in hungary. | 2008 | 18322771 |
| human dirofilariasis due to dirofilaria repens mimicking a scrotal tumor. | dirofilariasis due to dirofilaria repens is a rare anthropozoonotic disease, with dogs and cats being the definite hosts for this parasite. this worm is transmitted by various species of mosquitoes and usually presents as a subcutaneous nodule. human cases have been reported from all around the mediterranean, eastern europe, and central and southern asia. in the present case involving a 28-year-old patient of tunisian origin, infection manifested as a nodule in the left epididymis. in the contex ... | 2009 | 18384864 |
| wolbachia in dirofilaria repens causing human subcutaneous dirofilariosis. | human subcutaneous dirofilariosis is an increasingly reported zoonosis caused by several filarial species, in particular by dirofilaria (nochtiella) repens. like many filarial worms, d. repens harbours the bacterial endosymbiont wolbachia that has been implicated in the inflammatory features of filarial infection. immunohistochemical staining against the wolbachia surface protein (wsp) was carried out on 14 skin nodules and showed numerous bacteria within the intact worms and occasional positive ... | 2008 | 18576857 |
| ocular dirofilariasis in dubai, uae. | a rare occurrence of ocular subconjunctival dirofilariasis in a 53-year-old healthy indian male working in dubai, uae presenting with an acute red eye is reported. surgical excision under topical anesthesia was carried out uneventfully in the outpatient clinic. the live worm removed from the subconjunctival space was identified as dirofilaria repens on the basis of microscopic examination and histopathology. surgical excision of subconjunctival dirofilariasis is safe in an outpatient setting and ... | 2008 | 18579995 |
| autochthonous dirofilaria (nochtiella) repens infection in dogs in kuwait. | human dirofilariasis caused by dirofilaria repens is a rare but increasingly reported zoonosis in the middle east. however, eligible animal reservoirs seldom have been investigated in the area until now. seven (1.8 percent) out of 381 dogs examined in kuwait carried d. repens microfilariae showing compatible cutaneous clinical signs and positive response to the adulticide and microfilaricide therapies. this study indicates that dogs from kuwait are natural hosts of d. repens and therefore act as ... | 2008 | 18638183 |
| importance of aedes albopictus in veterinary medicine. | to assess the role of aedes albopictus in transmission of filarial nematodes of veterinary importance, researches were carried out in different geographical areas. in italy a first research was performed to study the susceptibility of ae. albopictus to dirofilaria repens, d. immitis and setaria labiatopapillosa. the development of l3 larvae was longer than in other species of mosquitoes but ae. albopictus could be a suitable vector of filariae. to understand the role of ae. albopictus in the nat ... | 2008 | 18693573 |
| survey of canine dirofilariasis in vojvodina, serbia. | in 2006 and 2007, a total of 193 blood samples were collected from privately owned dogs housed predominantly outdoors, resident in four provinces in vojvodina, serbian republic. circulating microfilariae of dirofilaria repens, dirofilaria immitis and acanthocheilonema reconditum were found in 49.2%, 7.2% and 2.1% of dogs, respectively. two additional occult heartworm infections were revealed with an antigen test of 90 amicrofilaraemic dogs. prevalence values were not influenced by sex and breed, ... | 2008 | 18712415 |
| three new cases of human infection with dirofilaria repens, one pulmonary and two subcutaneous, in the egyptian governorate of assiut. | human dirofilariasis caused by dirofilaria repens is a parasitic infection, currently considered to be an emerging zoonosis, that has been observed in many areas of the old world. dogs are the main 'reservoir' host. in humans, d. repens can cause inflammatory nodules, most commonly in the subcutaneous tissues or in the subconjunctival space. lung involvement, which is the most common of the non-cutaneous and non-ocular manifestations, is frequently mis-diagnosed as a primary or metastatic lung t ... | 2008 | 18782489 |
| zoonotic filariasis in the arabian peninsula: autochthonous onchocerciasis and dirofilariasis. | we describe zoonotic filariasis in two patients from kuwait; one with onchocerca spp. and one with dirofilaria spp. case 1, a 12-year-old kuwaiti woman who had visited saudi arabia, initially reported ocular symptoms. she later reported a nodule that appeared in the suprapubic area, which was resected. a coiled worm was observed in histologic sections and was identified as an onchocerca spp., but could not be definitively identified. this patient represents the 15th reported case of zoonotic onc ... | 2008 | 18981515 |
| [dirofilaria in the abdominal cavity]. | number of cases of filariasis have been recently reported in the hungarian medical literature, most of them caused by dirofilaria repens . dirofilaria repens is a mosquito-transmitted filarioid worm in the subcutaneous tissue of dogs and cats. human infection manifests as either subcutaneous nodules or lung parenchymal disease, which may even be asymptomatic. the authors report a human dirofilaria repens infection of the abdominal cavity in a 61-year-old man,who underwent laparotomy for acute ab ... | 2008 | 19028661 |
| a review of the off-label use of selamectin (stronghold/revolution) in dogs and cats. | since its introduction approximately seven years ago, selamectin (stronghold/revolution, pfizer inc.) has been used off-label to treat a number of ecto- and endoparasite conditions in dogs and cats. it has been used as a successful prophylactic against dirofilaria repens and as a treatment for aelurostrongylus abstrusus in cats. it has also been used to treat notoedric mange, infestation with the nasal mite pneumonyssoides caninum, cheyletiella spp. and neotrombicula autumnalis infestations and ... | 2008 | 19032763 |
| [arthropod-borne parasites of dogs, especially leishmania, in the kosovo and albania]. | currently no information is available regarding canine arthropod-borne parasites in albania and the kosovo, especially the zoonotic protozoan leishmania infantum. presumably autochtonous cases of human leishmaniosis have been described for some areas (kosovo: ferizaj, gjakovo, pec, malisevo; albania: tirana, durres, elbasan, shkodra, vlore). in order to investigate the infection status of dogs of different origin sera from 272 animals (151 from albania - tirana, kamza and durres; 121 from the ko ... | 2008 | 19066774 |
| [the first autochthonous case of subcutaneous dirofilariosis in austria]. | dirofilaria repens, a common parasite of carnivore mammals, is transmitted by mosquitos and may also infect humans accidentally causing a subcutaneous dirofilariosis. autochthonous infections of dogs, foxes or cats with d. repens has not been found in austria so far; however, 12 cases of imported subcutaneous dirofilariosis in man were noticed between 1981 and 2005. the recent case report deals with the 13(th) human case, which has to be considered as the first autochthonously acquired in austri ... | 2008 | 19066784 |
| [dirofilariasis--dirofilaria repens--first time described in polish patients]. | in this paper the first cases of human dirofilariasis in poland are presented. the clinical manifestations were typical subcutaneous nodules with the adult worm (d. repens) in the center. past medical history of the 5 patients revealed their trips to endemic countries, so the imported infection was considered. however 2 of these cases were difficult to interpret. it is unclear whether the infections should be considered endemic or imported, because of patients' short visits abroad which happened ... | 2008 | 19108517 |
| subcutaneous dirofilariasis caused by dirofilaria repens diagnosed by histopathologic and polymerase chain reaction analysis. | a 31-year-old man with a history of intravenous drug abuse presented with an inflamed subcutaneous nodule in his left thigh. the nodule measured up to 1.2 cm in largest diameter. under the clinical impression of an inflamed epidermal cyst or a subcutaneous abscess, surgical excision was performed. histopathologic examination of the nodule and subsequent polymerase chain reaction (pcr) analysis revealed the presence of the helminth dirofilaria (d.) repens, a member of the family filarioidea. diro ... | 2008 | 19111148 |
| wolbachia in dirofilaria repens, an agent causing human subcutaneous dirofilariasis. | human subcutaneous dirofilariasis is an increasingly reported zoonosis caused by several filarial species, in particular by dirofilaria (nochtiella) repens. like many filarial worms, d. repens harbors the bacterial endosymbiont wolbachia that has been implicated in the inflammatory features of filarial infection. immunohistochemical staining against the wolbachia surface protein (wsp) was carried out on 14 skin nodules and showed numerous bacteria within the intact worms and occasional positive ... | 2008 | 19127968 |
| autochthonous case of dirofilaria repens in a dog in the netherlands. | | 2009 | 19188352 |
| first case of cutaneous human dirofilariosis in slovak republic. | dirofilariosis is a zoonotic disease caused by several species of the genus of dirofilaria. the causative agent initiates a dangerous canine disease reported from many parts of the globe. the parasites are transmitted by arthropods, which act either as a vector or intermediate hosts. in humans the parasites do not usually reach the adult stage but microfilaremia is absent because of mating impossibility. human dirofilariosis is caused by d. immitis or d. repens and has been reported from many pa ... | 2008 | 19205556 |
| parasites on paper--the use of fta elute((r)) for the detection of dirofilaria repens microfilariae in canine blood. | storage of blood samples for subsequent dna extraction without loss of integrity can be difficult under field conditions. filter-based technologies are known to deliver good results for viral, bacterial and protozoan material but have not been tested for blood-dwelling stages of nematodes. in this study whatman fta elute (whatman plc, middlesex, uk) filter technology was tested for its ability to stabilise dna from blood samples of dogs naturally infected with dirofilaria repens for storage prio ... | 2009 | 19211188 |
| [dirofilaria repens in the netherlands]. | | 2009 | 19331072 |
| human dirofilaria repens infection in serbia. | human infection by dirofilaria repens in serbia has been increasing steadily. the first case was reported in 1971, presented in the form of a single subcutaneous nodule on the back of a young boy. as established by a literature search, eight additional cases were reported until mid-2001. the most frequent site of infection was subcutaneous tissue, with the exception of two cases, in which parasites were found in subconjunctiva and epididymis. our study, conducted from 2001 to 2008, encompasses 1 ... | 2009 | 19379543 |
| human dirofiliariasis in croatia. | dear editor, i read with great interest the article "subcutaneous dirofilariasis caused by dirofilaria repens diagnosed by histopathologic and polymerase chain reaction analysis", published in the last issue of acta dermatovenerologica croatica. the authors of the article describe a case of human dirofilariasis with typical subcutaneous presentation of the parasite. they cite this case as the fourth reported case of the disease in croatia (1). however, dirofilariasis in croatia has been reported ... | 2009 | 19386219 |
| [subconjunctival nodule with dirofilaria repens]. | dirofilaria repens infection, a zoonotic illness, is rarely seen in humans; it is more frequently met over the endemic areas of the southern europe and sri lanka. the authors report a case of dirofilaria conjunctivae in a 27 year old woman from craiova; such infections are hardly to be found in our country. our patient presented a mobile, bulbar, subconjunctival tumoral formation which was surgically removed; immature dirofilaria repens was revealed into it. case particularity was that the patie ... | 2009 | 19388575 |
| dirofilaria repens in the eyelid: case report of subcutaneous manifestation. | the authors report a case of eyelid subcutaneous filariasis. | 2009 | 19396798 |
| climate and dirofilaria infection in europe. | climatic changes, together with an increase in the movement of cats and dogs across europe, have caused an increase in the geographical range of several vector borne parasites like dirofilaria, and in the risk of infection for animals and humans. the present paper reviews the effects of climate and other global drivers on dirofilaria immitis and dirofilaria repens infections in europe and the possible implications on the transmission and control of these mosquito-borne nematodes. in the last sev ... | 2009 | 19398159 |
| intradural dirofilariasis mimicking a langerhans cell histiocytosis tumor. | we report the case of a 6-year-old female who presented a cervical intradural extra-spinal tumor, initially considered as a langerhans cell histiocytosis. additional histological slides revealed a dirofilaria repens dirofilariasis. the particularity of this case is the intradural location of this filariasis, which usually has a subcutaneous or conjunctival location in human. | 2009 | 19489058 |
| [detection of dirofilaria in austrian dogs]. | a recent increase in the occurrence of dirofilaria repens and dirofilaria immitis has been reported from the eastern neighbouring countries of austria (slovakia, hungary). in order to obtain data from austria--especially from the areas bordering these countries--blood samples of dogs from gänserndorf (northeastern austria, bordering slovakia) and neusiedl (eastern austria, bordering hungary) were examined for the presence of dirofilaria spp.-dna by quantitative real-time pcr (qpcr). for d. repen ... | 2009 | 19517934 |
| cutaneous dirofilariasis presenting as an eyelid swelling. | dirofilariasis is a common filarial infection occurring in domestic and wild animals as a result of arthropod bites. however, it can be transmitted to humans after mosquito bites. here, we report a case of a 54-year-old lady who developed an unilateral eyelid swelling secondary to dirofilaria repens. | 2009 | 19535767 |
| recently recognized cases of ophthalmofilariasis in hungary. | to report four cases of zoonotic ophthalmodirofilariasis infection caused by dirofilaria repens in hungary. | 2009 | 19551686 |
| current surveys on the prevalence and distribution of dirofilaria spp. in dogs in germany. | the central upper-rhine (baden-württemberg, germany) is one of the warmest regions in germany and also harbours abundant numbers of mosquitoes. case reports on presumably autochthonous occurrence of dirofilaria spp. were reported previously and were a reason for a further investigation into the occurrence of vector-borne pathogens. for this purpose, 44 hunting dogs from the central upper-rhine region were tested between 4(th) and 29(th) june 2007. the blood samples were tested using the knott's ... | 2009 | 19575227 |
| subcutaneous dirofilariasis caused by dirofilaria repens in greece: a case report. | dirofilaria repens (formerly dirofilaria conjunctiva) is a natural parasite of the subcutaneous tissues of dogs, cats and wild carnivores in europe, africa and asia. microfilariae are transmitted to humans by various species of mosquito. an autochthonous case of subcutaneous dirofilariasis is reported in a greek patient from the island of corfu. the clinical manifestation of the infection was a palpable, painless, subcutaneous nodule in the region of the groin, which 2 days before the patient co ... | 2009 | 19586500 |
| dirofilaria infections in working dogs in slovakia. | a monitoring programme aimed at the diagnosis of subcutaneous dirofilariasis and heartworm disease in working (police and military) dogs in slovakia has been performed during the period of september 2007 to february 2008. in co-operation with the ministry of the interior and the ministry of defence, in total, 710 dogs (591 police dogs and 119 military dogs) were investigated for the presence of microfilariae in blood. all police and military dogs in active service held on the territory of slovak ... | 2010 | 19728899 |
| fibrous subcutaneous nodule caused by dirofilaria repens. | a case is described of subcutaneous dirofilariasis in a greek woman who had visited many countries around the world, including areas of sub-saharan africa. the patient presented with a single hard subcutaneous nodule on the right cheek, with no cutaneous manifestations of early or long-standing onchocercal dermatitis or eye lesions. the nodule was removed surgically and the filarial adult worm onchocerca volvulus was initially diagnosed, based on the history, the hardness and large size of the f ... | 2009 | 19747670 |
| [biological characteristics of the causative agent of dirofilariasis in dogs in the rostov region]. | this paper assesses the trends in the identification of different dirofilaria species in the rostov region and comparatively analyzes the general clinical and biochemical blood indices in dogs with and without helminthism. seasonal variations in the invasion and species composition of the parasite have been established. at present, there is a gradual replacement of the species dirofilaria repens by dirofilaria immitis in this area. the blood general clinical and biochemical studies in ill dogs w ... | 2009 | 19827508 |
| dirofilaria causing eye infection in a patient from malaysia. | human dirofilariasis caused by dirofilaria immitis and dirofilaria repens have been reported in malaysia. this is the fourth reported case of dirofilariasis caused by d. repens. the patient was a chinese male from kuching sarawak, malaysia who presented with a one day history of redness and itchiness over the temporal aspect of his left eye. a worm was seen and later removed from beneath the conjunctiva under local anesthesia and based on the morphological characteristics, it was identified as a ... | 2009 | 19842373 |
| dirofilaria repens infection and concomitant meningoencephalitis. | dirofilaria repens, a filarial nematode of dogs and other carnivores, can accidentally infect humans. clinical symptoms are usually restricted to a subcutaneous nodule containing a single infertile parasite. here, we report a case of d. repens infection with a subcutaneous gravid worm and the patient's concomitant meningoencephalitis and aphasia. | 2009 | 19891881 |
| [a worm infection in the skin of a dog. first autochthonous dirofilaria repens infection ofa dog in the netherlands]. | the history of an 18-month-old english bulldog with a painful lump in the skin on its thigh is described. after opening the nodule a few dirofilaria repens nematodes were found. oval-shaped transparent eggs with moving larvae were seen microscopically. the dog was treated with milbemycin and made a complete recovery. the dog had never been abroad, but 6 months earlier in early may had been on a campsite in the middle of the netherlands where many mosquitoes were present. this is the first descri ... | 2009 | 20055026 |
| dirofilariasis: a rare case report. | human dirofilariasis is a zoonotic infection most commonly caused by dirofilaria repens. it has not been widely recognized in india. there is probably a focus of human infection with d. repens in kerala. we report the first case of dirofilariasis, from the eastern-part of india, to the best of our knowledge. among the documented cases of human dirofilariasis caused by d. repens, recorded in india, most of them had ocular infections and few had subcutaneous involvement of the face. this is the fi ... | 2010 | 20061774 |
| ocular dirofilariasis. | dirofilaria is a parasite of domestic and wild animals that can infect humans accidentally. it is being reported in increasing numbers from mediterranean countries like italy. in india this infection is occasionally being reported. we report three cases of ocular dirofilariasis from the state of assam presenting as periorbital and subconjunctival cysts. the parasites were identified as dirofilaria repens. the purpose of this article is to take note of this emerging zoonosis in assam; also to rev ... | 2010 | 20090252 |
| autochthonous foci of canine and feline infections by dirofilaria immitis and dirofilaria repens in central italy. | this survey was conducted to investigate the presence of dirofilaria immitis and dirofilaria repens in native dogs and cats living in an area of italy where animal and human dirofilarioses have been sporadically reported in the past few years. from may 2008 to march 2009 individual blood samples were collected from 300 native cats and 300 native dogs in the abruzzo region of central italy. all 600 samples were subjected to a knott modified method, to a test for the detection of circulating d. im ... | 2010 | 20097479 |
| canine and feline vector-borne diseases in italy: current situation and perspectives. | in italy, dogs and cats are at risk of becoming infected by different vector-borne pathogens, including protozoa, bacteria, and helminths. ticks, fleas, phlebotomine sand flies, and mosquitoes are recognized vectors of pathogens affecting cats and dogs, some of which (e.g., anaplasma phagocytophilum, borrelia burgdorferi, dipylidium caninum, leishmania infantum, dirofilaria immitis, and dirofilaria repens) are of zoonotic concern. recent studies have highlighted the potential of fleas as vectors ... | 2010 | 20145730 |
| elimination of dirofilaria (syn. nochtiella) repens microfilariae in dogs with monthly treatments of moxidectin 2.5%/imidacloprid 10% (advocate, bayer) spot-on. | elimination of microfilaria in dogs infected with zoonotic dirofilaria repens would be desirable to reduce further spread. moxidectin has demonstrated efficacy against microfilariae and safety in dogs infected with dirofilaria immitis and could be an option for controlling d. repens microfilariae. a field study with 64 dogs previously confirmed positive for d. repens microfilaria was conducted in hungary, in which a spot-on product (advocate, bayer) was tested. treatments were applied to 44 dogs ... | 2010 | 20165873 |
| efficacy of moxidectin microsphere sustained release formulation for the prevention of subcutaneous filarial (dirofilaria repens) infection in dogs. | a study was carried out to assess the efficacy of a moxidectin microsphere sustained release (sr) injectable formulation (guardian sr iniettabile, fort dodge) for the prevention of dirofilaria repens infection in experimentally infected dogs. on day 0, 18 beagle dogs, 9 male dogs and 9 female dogs, weighing 12-16 kg were ranked in ascending order of body weight (b.w.) and blocked into pairs. within each pair, dogs were allocated to group 1 or group 2 at random. on the same day, dogs in group 1 w ... | 2010 | 20193980 |
| identification of immunoreactive proteins of dirofilaria immitis and d. repens recognized by sera from patients with pulmonary and subcutaneous dirofilariosis. | human pulmonary and subcutaneous dirofilariosis caused by dirofilaria immitis and dirofilaria repens are worldwide diagnosed with increasing frequency. these species are responsible for the development of benign pulmonary and subcutaneous nodules, respectively, that can be confused with lung or cutaneous cancer. the aim of the present work was to identify d. immitis and d. repens proteins differentially recognized by serum samples from individuals with human pulmonary and subcutaneous dirofilari ... | 2010 | 20197111 |
| [the first foci of dirofilariosis of dogs evoked by dirofilaria repens railliet et henry, 1911 in central poland]. | dirofilariosis is caused by nematodes dirofilaria repens railliet et henry, 1911. this parasitosis is widely distributed in south europe among dogs, cats and wild carnivorous. it occurs also in asia and africa. adult nematodes d. repens locate in nodules, in subcutaneous or intramuscular connective tissue of dogs. the mosquitoes from genera anopheles, aedes and culex are the intermediate hosts and vectors of mentioned parasites. the finding of 6 adult nematodes belonging to the species d. repens ... | 2009 | 20209810 |
| climate changes implicated for dirofilaria dissemination in slovakia. | dirofilariosis is a parasitic disease caused by helminths of the genus dirofilaria. climatic changes are considered to be main risk factors for dirofilariosis spreading. in the slovak republic, canine subcutaneous dirofilariosis was recorded for the first time in 2005. in 2007 the first coordinated research project started to detect possible endemic infections and to determine their magnitude. a total of 984 dogs were examined for the presence of microfilariae within 2007-2008. modified knott te ... | 2009 | 20209820 |
| [subcutaneous dirofilariasis of the upper lip in tunisia]. | dirofilariasis is a rare anthroponotic disease caused by dirofilaria, the principal reservoir of which is the dog. the first case of subcutaneous dirofilariasis in tunisia was reported in 1990. | 2010 | 20335098 |
| [human dirofilariasis in the tula region]. | the paper describes cases of dirofilariasis in the residents of tula and the tula region. one of the cases does not fit into the traditional concepts. on excising a tumor in an adolescent, two live actively moving nonencapsulated helminths: a male and a female dirofilaria repens worms were removed, which were identified at the parasitology laboratory, center of hygiene and epidemiology in the tula region. | 2010 | 20361637 |
| swiss patient with a subconjunctival dirofilaria repens. | | 2010 | 20408091 |
| highly sensitive multiplex pcr for simultaneous detection and discrimination of dirofilaria immitis and dirofilaria repens in canine peripheral blood. | dirofilaria immitis and dirofilaria repens are the most common species of filarial nematodes described in the dogs with increasing spread into new geographical areas. the diagnosis of canine dirofilariosis is usually based upon the microscopical detection and identification of circulating microfilariae together with elisa detection of serum circulating heartworm antigens or antibodies. the identification of the parasite species using the traditional approaches sometimes can be difficult and can ... | 2010 | 20483540 |
| a human case of subcutaneous dirofilariasis caused by dirofilaria repens in vietnam: histologic and molecular confirmation. | human dirofilariasis caused by infection with dirofilaria worms has been frequently reported. the symptoms associated with infection by these filarial parasites, which are transmitted to humans by zooanthropophilic mosquitoes, are characterized by mainly pulmonary and subcutaneous nodules. here, we report the first case in vietnam of a subcutaneous dirofilariasis with a painful nodule in the right eyelid. an immature female worm was removed by excisional biopsy and identified as dirofilaria repe ... | 2010 | 20593195 |
| [ocular dirofilariasis: a case report]. | a case of ocular dirofilariasis in a female patient is presented. the zoonosis caused by parasites of the genus dirofilaria is relatively rare in humans, with a higher incidence in south and central europe, asia and africa. in europe, dirofilariasis is mostly caused by the species dirofilaria repens. in the past 50 years, the number of individuals involved has been on an increase, with about 780 cases reported in the literature to date. dirofilaria is a parasite found in the dog, cat, racoon and ... | 2010 | 20653124 |
| human dirofilariosis in the slovak republic - a case report. | the spread of dirofilariosis, as a newly emerging zoonosis, due to global changes has been documented in several central european countries. in slovakia, the first autochthonous case of dirofilariosis was recorded in dogs in 2005. the first case of human subcutaneous dirofilariosis caused by dirofilaria repens was diagnosed in a 60- year-old patient from an area of western slovakia. we report another case of dirofilariosis in a 37-year-old woman living in the same area of south-western slovakia. ... | 2010 | 20684496 |
| strong expression of tgf-beta in human host tissues around subcutaneous dirofilaria repens. | dirofilaria repens and other dirofilaria species are widely distributed parasitic nematodes of carnivores, which occasionally are transmitted to men, causing subcutaneous nodules. in humans, it usually occurs only as single male or female filariae without production of microfilariae. the non-productive living or dead dirofilaria worms in subcutaneous biopsies from 15 human patients permitted us to study the role of the pleiotropic and immunoregulatory cytokine transforming growth factor beta (tg ... | 2011 | 20809419 |
| helminthic infections mimicking malignancy: a review of published case reports. | infectious diseases, including infections with helminths, can initially present similarly to malignancies. the goal of the article is to review reports of helminthic infections that are initially diagnosed as malignancy. | 2010 | 20818089 |
| several cases of dirofilariosis accidentally diagnosed in dogs from poland, including two pcr positive dirofilaria repens cases. | the aim of the present study was a description of several microfilaremia cases diagnosed in dogs from poland. the study was conducted on cytological samples of pathologic masses and peripheral blood smears taken for diagnostic purposes from dogs showing a various clinical findings. the presence of the parasites in tissue samples was observed in 8 dogs, additionally, in 2 of these dogs pcr analysis of blood samples revealed the presence of d. repens dna. | 2010 | 21033571 |
| [an unusual cause of hand nodule: peri-tendon dirofilariasis]. | dirofilariasis is a zoonosis affecting dogs and cats. it was transmitted to man by mosquito bites. human dirofilariasis is rare. we report a case of 4-year-old girl presented with a subcutaneous palmar nodule of the hand. surgical excision shows a nodule encircling the forth flexor tendon. the histological examination established the diagnosis by the presence of an adult worm identified as dirofilaria repens. surgical excision was curative. | 2010 | 21087885 |
| preliminary findings on the efficacy of selamectin in the treatment of dogs naturally infected with dirofilaria repens. | subcutaneous dirofilariosis caused by dirofilaria repens is common in dogs and it is an emerging helminthozoonosis in europe, asia, africa and also in hungary. macrocyclic lactones are used for preventing the infection; however, their activity against the microfilariae and mature stages of this species is questionable. selamectin is widely used for the prophylaxis of heartworm (d. immitis) infection. the objective of the present study was to test the microfilaricidal efficacy of the topical form ... | 2010 | 21087910 |
| images in clinical medicine: subconjunctival dirofilaria repens. | | 2010 | 21158653 |
| [autochthonous filaria in south-west france caused by dirofilaria repens]. | dirofilariasis is an autochthonous disease caused by dirofilaria (nochtiella) repens, a subcutaneous parasite of dogs and other carnivorous animals. human infection leads to a self-limiting disease that generally presents clinically as a subcutaneous nodule. we describe a case occurring outside the classical endemic mediterranean region. | 2010 | 21276463 |
| geographical information systems as a tool in the control of heartworm infections in dogs and cats. | geospatial tools (e.g., geographical information systems, remote sensing, global positioning systems, and virtual globes) are very useful for the simultaneous visualization of health data with environmental data, which holds promise to understand environmental-health linkages and to generate new hypotheses to be tested in future research. current epidemiological studies clearly show that the distribution patterns of vector-borne infections are changing; for example, in europe, heartworm infectio ... | 2011 | 21292404 |
| changing climate and changing vector-borne disease distribution: the example of dirofilaria in europe. | climatic changes, together with an increase in the movement of dogs across europe, have caused an increase in the geographical range of dirofilaria infections. the present paper is focuses on northeastern european countries, where survey data have shown an increase of dirofilaria repens infections both in animals and humans. a growing degree day-based forecast model has been developed to predict the occurrence. the model is based on evidence that there is a threshold of 14 °c below which dirofil ... | 2011 | 21300439 |
| dirofilarial infections in europe. | abstract nematodes of the genus dirofilaria are currently considered emerging agents of parasitic zoonoses in europe. climatic changes and an increase in the movement of reservoirs (mostly infected dogs) have caused an increase in the geographical range of these parasites from the traditionally endemic/hyperendemic southern regions, and the risk for human infection has increased. in the last several years, forecast models have predicted that current summer temperatures are sufficient to facilita ... | 2011 | 21417922 |
| efficacy of a single administration of a spot-on solution containing imidacloprid 10%/moxidectin 2.5% in eliminating dirofilaria repens microfilariae in naturally infected dogs. | in the past decade reports of canine subcutaneous dirofilariosis, caused by the mosquito-transmitted nematode dirofilaria repens, increased in number in several countries in europe, along with a rise of human cases. given the merit to the new approaches for the control and treatment of this infection, the present study evaluated the efficacy of a single application of the spot-on formulation containing imidacloprid 10%/moxidectin 2.5% (advocate(-«), bayer animal health) in the elimination of d. ... | 2011 | 21435791 |
| a first human case of ocular dirofilariosis due to dirofilaria repens in northeastern france. | we report the first case of ocular dirofilariasis to be diagnosed in northeast france (alsace region), in a man who presented with a suborbital mass after a journey to senegal. microscopic examination of the surgical specimen identified dirofilaria repens. | 2011 | 21461355 |
| [human dirofilariasis: a new french case report with dirofilaria repens.] | dirofilariosis is an endemic filarial parasitic disease in the mediterranean basin, unfamiliar in france. its incidence and geographic area are increasing due to global warming. dogs and cats are the usual hosts, but humans may be accidentally infected. we reported the 91(st) case of french dirofilariosis, contracted in camargue (south france) which appeared as a subcutaneous abdominal nodule. ultrasound strongly guided the diagnosis by showing a linear structure moving in a fibrocystic structur ... | 2011 | 21492973 |
| human ocular infection with dirofilaria repens (railliet and henry, 1911) in an area endemic for canine dirofilariasis. | abstract. dirofilaria repens, which is usually found in canine subcutaneous tissues, is the main causative agent of human dirofilariasis in the old word. however, a relationship between animal and human cases of dirofilariasis caused by d. repens in a given area has never been demonstrated. the uneven distribution of d. repens in provinces in sicily, italy represented the foundation for this study. we report a human case of ocular infection with d. repens from trapani province, where canine diro ... | 2011 | 21633041 |
| effect of therapy by using advocate spot-on combination (imidacloprid 10% and moxidectin 2.5%) on subcutaneous dirofilariosis in dogs. | dirofilaria (nochtiella) repens is a filarioid parasite that causes subcutaneous dirofilariosis in dogs. adults, while localized in subcutaneous tissues, lay embryos (microfilariae (mf)) into the blood stream of dogs, which constitute a reservoir for infection of other definitive or accidental hosts as humans. this study was carried out to assess the efficacy of spot-on combination of imidacloprid and moxidectin on microfilariaemia in naturally infected dogs. a group of 11 dogs was monthly exami ... | 2011 | 21776349 |
| evaluation of the therapeutic and preventive efficacy of 2.5 % moxidectin / 10 % imidacloprid (advocate(®), bayer animal health) in dogs naturally infected or at risk of natural infection by dirofilaria repens. | the objective of this gcp-compliant clinical field study was to evaluate the efficacy of the combination of moxidectin (minimum dose of 2.5 mg/kg body weight) and imidacloprid (minimum dose of 10.0 mg/kg body weight) spot-on (advocate(®)) as a preventive and therapeutic treatment of natural infection by dirofilaria repens in dogs in the czech republic.there were two arms of the study, both negatively controlled. 34 animals were randomly allocated to two groups of the treatment arm; 90 negative a ... | 2011 | 21739377 |
| diagnosis of imported canine filarial infections in germany 2008 - 2010. | filarial infections of dogs are attracting attention across europe because of the risk of spread into previously non-endemic areas (e.g. dirofilaria repens with culicidae as vectors) and as emerging zoonotic agents. the occurrence of filarial infections in german dogs has been analysed based on 8,545 samples collected either from imported animals or following travel into endemic regions. all samples were tested by means of modified knott's test and heartworm antigen assay within the period 2008 ... | 2011 | 21739376 |
| subconjunctival dirofilaria repens infestation: a light and scanning electron microscopy study. | to present a case of subconjunctival infestation with dirofilaria repens which is very rare in northern europe. | 2011 | 21738560 |
| subcutaneous human dirofilariasis due to dirofilaria repens: report of two cases. | zoonotic filariasis due to dirofilaria repens (d. repens) is prevalent in several regions of the world. in view of recent rise of human d. repens infections in europe, africa and asia, it is considered an emerging zoonosis in these continents. most of the documented cases of human dirofilariasis recorded in india had ocular infections, but very few subcutaneous dirofilariasis have been reported. we hereby report two cases of subcutaneous human dirofilariasis due to d.repens with varied clinical ... | 2011 | 21731311 |
| clinical aspects of dermatitis associated with dirofilaria repens in pets: a review of 100 canine and 31 feline cases (1990-2010) and a report of a new clinic case imported from italy to dubai. | cutaneous dirofilariasis is a parasitic disease caused by the mosquito-borne filarial nematodes dirofilaria (nochtiella) repens, living in the subcutaneous tissue of dogs, cats, wild carnivores, and humans. cases have been recently reported also from germany, czech republic, hungary, ukraine, russia, austria, switzerland, france, the netherlands, and the middle east. d. repens is not widely known to cause chronic pruritic dermatitis in animals. dermatological signs observed in 100 canine clinic ... | 2011 | 22203888 |
| Macrocyclic Lactones in the Treatment and Control of Parasitism in Small Companion Animals. | Macrocyclic lactones (MLs) have many anti-parasitic applications in small companion animal medicine. They were first developed as chemoprophylactics against heartworm (Dirofilaria immitis) infection to be applied monthly for retroactive killing of third- and fourth-stage larvae. ML-containing products formulated for oral (ivermectin, milbemycin oxime), topical (selamectin, moxidectin) or injectable sustained release (moxidectin, ivermectin) are approved for heartworm prevention in dogs or cats ... | 2011 | 22039798 |
| a duplex real-time polymerase chain reaction assay for the detection of and differentiation between dirofilaria immitis and dirofilaria repens in dogs and mosquitoes. | this study describes a duplex real-time polymerase chain reaction (pcr) assay for the detection and differentiation between dirofilaria immitis and dirofilaria repens in dog blood and mosquitoes. regions of a cytochrome oxidase 1 (cox1) mitochondrial dna fragment and the second internal transcribed spacer (its-2) of nuclear ribosomal dna were amplified from microfilariae and adult worm samples, using a sensitive ssofast™ evagreen(®) based real-time pcr method coupled with melting-curve analysis. ... | 2011 | 22119343 |
| epidemiological aspects on vector-borne infections in stray and pet dogs from romania and hungary with focus on babesia spp. | canine arthropod-borne infections are of major interest in small animal practice and have been widely investigated in central and western europe. however, only limited epidemiological data are available from south-eastern european countries, although diseases including babesiosis or dirofilariosis are widely recognised as important canine infections in these countries. a steadily increasing number of dogs imported from south-eastern europe into germany require particular attention by small anima ... | 2011 | 21947342 |
| detection of specific antibodies in dogs infected with angiostrongylus vasorum. | canine angiostrongylosis, caused by the nematode angiostrongylus vasorum, is an emerging cardiopulmonary disease in europe which can be fatal if left untreated. we determined the diagnostic value of the specific detection of antibodies against a. vasorum adult somatic antigen, adult excretory/secretory (e/s) antigen and first stage larvae (l1) somatic antigen in elisas. also, a. vasorum adult somatic antigen purified by monoclonal antibodies (mab) was evaluated in a sandwich-elisa. among the cru ... | 2011 | 22051072 |
| a multiplex pcr for the simultaneous detection of species of filarioids infesting dogs. | the present study reports the applicability of a multiplex pcr for the simultaneous detection and differentiation of common filarioids infecting dogs, i.e., dirofilaria immitis and dirofilaria repens, acanthocheilonema reconditum and cercopithifilaria sp. amplicons of different sizes (i.e., 170bp, 480bp, 590bp and 300bp, respectively) of regions within the mitochondrial cytochrome c oxidase subunit 1 (cox1) gene were amplified on a single-step multiplex pcr using a mix of species-specific forwar ... | 2012 | 22248527 |
| on a cercopithifilaria sp. transmitted by rhipicephalus sanguineus: a neglected, but widespread filarioid of dogs. | abstract: | 2012 | 22212459 |
| subcutaneous human dirofilariasis. | subcutaneous human dirofilariasis is caused by the zoonotic filariae dirofilaria repens. the frequency of reports is increasing in literature during the last few years and is considered by some authors as an emerging zoonosis. here we report 21 cases of subcutaneous dirofilariasis, which were encountered over a period of 8 years. none of these cases were associated with peripheral eosinophilia. since these lesions can mimic benign and malignant tumors, it is important to consider this as a diffe ... | 2011 | 23024495 |
| human dirofilaria repens infection in romania: a case report. | human dirofilariasis is a zoonotic infectious disease caused by the filarial nematodes of dogs dirofilaria repens and dirofilaria immitis. depending on the species involved, human infections usually manifest as one cutaneous or visceral larva migrans that forms a painless nodule in the later course of disease. dirofilariae are endemic in the mediterranean, particularly in italy. they are considered as emerging pathogens currently increasing their geographical range. we present one of the few kno ... | 2012 | 22567488 |
| seroprevalence of some vector-borne infections of dogs in hungary. | the first comprehensive study on the prevalence of canine vector-borne pathogens (anaplasma phagocytophilum, borrelia burgdorferi, ehrlichia canis, and dirofilaria immitis) was carried in hungary because, except for babesiosis and dirofilariosis caused by dirofilaria repens, there were no data on their regional distribution and prevalence. in 2011 and 2012, 1305 blood samples were collected from randomly selected, apparently healthy pet dogs in 167 localities of 19 counties of hungary. all sera ... | 2014 | 24689833 |
| the first case of human autochtonous subconjunctival dirofilariosis in poland and malt lymphoma as possible consequence of this parasitosis. | the first case of human dirofilarosis in poland was recorded in 2007. until that time our country was free of dirofilaria repens. recent studies show that 21,4- 60% of dogs in warsaw region harbour microfilariae, therefore it is becoming a growing problem in central europe. in april 2013 a subconjunctival d. repens was removed from the eye of 61-year-old woman. it was the twenty first case of this disease in poland, the third case of eye dirofilaria and the fourth autochtonous case. the patient ... | 2015 | 25589901 |
| mosquitoes (diptera: culicidae) and their relevance as disease vectors in the city of vienna, austria. | mosquitoes (diptera: culicidae) are important vectors for a wide range of pathogenic organisms. as large parts of the human population in developed countries live in cities, the occurrence of vector-borne diseases in urban areas is of particular interest for epidemiologists and public health authorities. in this study, we investigated the mosquito occurrence in the city of vienna, austria, in order to estimate the risk of transmission of mosquito-borne diseases. mosquitoes were captured using di ... | 2014 | 25468380 |
| molecular xenomonitoring of dirofilaria immitis and dirofilaria repens in mosquitoes from north-eastern italy by real-time pcr coupled with melting curve analysis. | dirofilaria immitis and dirofilaria repens are transmitted by bloodsucking culicid mosquitoes belonging to culex, aedes, ochlerotatus, anopheles and mansonia genera. the detection of filarioids in mosquitoes for assessing distribution of vectors and/or of pathogens in a given area (also known as "xenomonitoring"), when based on individual dissection of wild-caught female mosquitoes is time consuming and hardly applicable in large epidemiological surveys. our study aimed to evaluate the recently ... | 2012 | 22520170 |
| molecular detection of dirofilaria immitis, dirofilaria repens and setaria tundra in mosquitoes from germany. | as a result of globalization and climate change, dirofilaria immitis and dirofilaria repens, the causative agents of dirofilariosis in europe, continue to spread from endemic areas in the mediterranean to northern and northeastern regions of europe where autochthonous cases of dirofilarial infections have increasingly been observed in dogs and humans. whilst d. repens was recently reported from mosquitoes in putatively non-endemic areas, d. immitis has never been demonstrated in mosquitoes from ... | 2014 | 24433279 |