| The impact of a consortium of fermented milk strains on the gut microbiome of gnotobiotic mice and monozygotic twins. | Understanding how the human gut microbiota and host are affected by probiotic bacterial strains requires carefully controlled studies in humans and in mouse models of the gut ecosystem where potentially confounding variables that are difficult to control in humans can be constrained. Therefore, we characterized the fecal microbiomes and metatranscriptomes of adult female monozygotic twin pairs through repeated sampling 4 weeks before, 7 weeks during, and 4 weeks after consumption of a commercial ... | 2011 | 22030749 |
| characterization of bifidobacteria suitable for probiotic use in calves. | in our previous experiment, the ten calves originated bifidobacterial strains were administered to calves and re-isolated. fingerprinting techniques used in this study enabled us to distinguish the surviving and non-surviving strains. only the species bifidobacterium animalis ssp. animalis and bifidobacterium longum ssp. suis were found to survive in the intestine. | 2011 | 21986032 |
| Longevity in mice is promoted by probiotic-induced suppression of colonic senescence dependent on upregulation of gut bacterial polyamine production. | Chronic low-grade inflammation is recognized as an important factor contributing to senescence and age-related diseases. In mammals, levels of polyamines (PAs) decrease during the ageing process; PAs are known to decrease systemic inflammation by inhibiting inflammatory cytokine synthesis in macrophages. Reductions in intestinal luminal PAs levels have been associated with intestinal barrier dysfunction. The probiotic strain Bifidobacterium animalis subsp. lactis LKM512 is known to increase inte ... | 2011 | 21858192 |
| Short communication: the complete genome sequence of Bifidobacterium animalis subspecies animalis ATCC 25527(T) and comparative analysis of growth in milk with B. animalis subspecies lactis DSM 10140(T). | The objective of this work was to sequence the genome of Bifidobacterium animalis ssp. animalis ATCC 25527(T), the subspecies most closely related to B. animalis ssp. lactis, some strains of which are widely added to dairy foods as probiotics. The complete 1,932,963-bp genome was determined by a combination of 454-shotgun sequencing and PCR gap closing, and the completed assembly was verified by comparison with a KpnI optical map. Comparative analysis of the B. animalis ssp. animalis ATCC 25527( ... | 2011 | 22118077 |
| Effects of daily consumption of probiotic yoghurt on inflammatory factors in pregnant women: a randomized controlled trial. | Previous studies have shown that inflammatory factors increases in pregnancy and is associated with several complications of pregnancy. The aim of this study was to assess effects of daily consumption of probiotic yoghurt on inflammatory factors in pregnant women. In a randomized clinical trial, seventy primigravid (the first pregnancy) and singleton pregnant women aged 18-30 years were assigned to two groups. Subjects consumed daily 200 g probiotic yoghurt containing Lactobacillus acidophilus L ... | 2011 | 21936251 |
| genome sequence of the probiotic strain bifidobacterium animalis subsp. lactis cncm i-2494. | bifidobacterium animalis subsp. lactis cncm i-2494 is part of a commercialized fermented dairy product with documented health benefits revealed by multiple randomized placebo-controlled clinical trials. here we report the complete genome sequence of this strain, which has a circular genome of 1,943,113 bp with 1,660 open reading frames and 4 ribosomal operons. | 2011 | 21914878 |
| Complete genome sequence of Bifidobacterium animalis subsp. lactis BLC1. | Bifidobacterium animalis subsp. lactis BLC1 is a probiotic bacterium that is widely exploited by food industries as the active ingredient of various functional foods. Here we report the complete genome sequence of B. animalis subsp. lactis BLC1, which is expected to provide insights into the biology of this health-promoting microorganism and improve our understanding of its phylogenetic relatedness with other members of the B. animalis subsp. lactis taxon. | 2011 | 22038957 |
| late rather than early responses of human dendritic cells highlight selective induction of cytokines, chemokines and growth factors by probiotic bacteria. | the probiotic properties of commensal bacteria including lactobacilli and bifidobacteria are likely to be determined at least in part by their effects on dendritic cells. like traditional immune stimulants such as lipopolysaccharides (lps), probiotic bacteria promote maturation of cultured human dendritic cells (dc) by inducing elevated expression of mhc-ii and co-stimulatory molecules. different effects have been reported on cytokine induction, especially of major regulatory cytokines such as t ... | 2010 | 21840799 |
| effect of a synbiotic yogurt on levels of fecal bifidobacteria, clostridia and enterobacteria. | while ingestion of synbiotic yogurts containing bifidobacterium animalis subsp. lactis and inulin are increasing, their effect on certain microbial groups in the human intestine is unclear. to further investigate this, a large-scale, cross-over design, placebo controlled study was utilized to evaluate the effect of a synbiotic yogurt containing b. animalis subsp. lactis bb-12 and inulin on the human intestinal bifidobacteria, clostridia, and enterobacteria. fecal samples were collected at 14 tim ... | 2011 | 22101054 |
| fibers from fruit by-products enhance probiotic viability and fatty acid profile and increase cla content in yoghurts. | this study evaluated the effect of the supplementation of total dietary fiber from apple, banana or passion fruit processing by-products on the post-acidification, total titratable acidity, bacteria counts and fatty acid profiles in skim milk yoghurts co-fermented by four different probiotics strains: lactobacillus acidophilus l10 and bifidobacterium animalis subsp. lactis bl04, hn019 and b94. apple and banana fibers increased the probiotic viability during shelf-life. all the fibers were able t ... | 2011 | 22264421 |
| lactobacillus rhamnosus gg and bifidobacterium animalis mb5 induce intestinal but not systemic antigen-specific hyporesponsiveness in ovalbumin-immunized rats. | probiotics may modulate the host immune response by mechanisms not yet fully understood. we evaluated the modulation of intestinal and systemic antigen-specific immune response by lactobacillus rhamnosus gg (lgg) or bifidobacterium animalis mb5 in tolerized and immunized rats. three groups of rats received orally lgg, b. animalis, or pbs (control) for 28 d. each group was divided into two subgroups of tolerized or immunized rats receiving orally ovalbumin (ova; 7 mg) or pbs on d 7, 9, and 11. al ... | 2012 | 22223570 |
| bifidobacterium lactis bb12 enhances intestinal antibody response in formula-fed infants: a randomized, double-blind, controlled trial. | background: addition of probiotics to infant formula may positively affect immune function in nonexclusively breastfed infants. this study aimed to investigate the effect of infant starter formula containing the probiotic bifidobacterium animalis subspecies lactis (bb12) on intestinal immunity and inflammation. methods: six-week-old healthy, full-term infants (n = 172) were enrolled in a prospective, randomized, double-blind, controlled clinical trial with 2 groups studied in parallel to a breas ... | 2012 | 22237870 |
| rapid and accurate bacterial identification in probiotics and yoghurts by maldi-tof mass spectrometry. | probiotic food is manufactured by adding probiotic strains simultaneously with starter cultures in fermentation tanks. here, we investigate the accuracy and feasibility of matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry (maldi-tof ms) for bacterial identification at the species level in probiotic food and yoghurts. probiotic food and yoghurts were cultured in columbia and lactobacillus specific agar and tested by quantitative real-time pcr (qpcr) for the detection an ... | 2011 | 22417598 |
| survival, acid and bile tolerance, and surface hydrophobicity of microencapsulated b. animalis ssp. lactis bb12 during storage at room temperature. | survival, acid and bile tolerance, and surface hydrophobicity of microencapsulated bifidobacterium animalis ssp. lactis bb12 were studied during storage at room temperature (25 °c) at low water activity (0.07, 0.1, and 0.2). two types of alginate-based systems were prepared with and without mannitol as microencapsulant of b. animalis ssp. lactis bb12. formation of gel beads containing cells was achieved by dropping each emulsion into cacl(2) solution; then, the beads were freeze dried. survival, ... | 2011 | 22416710 |
| rapid discrimination of bifidobacterium animalis subspecies by matrix-assisted laser desorption ionization-time of flight mass spectrometry. | currently, the species bifidobacterium animalis consists of two subspecies, b. animalis subsp. lactis and b. animalis subsp. animalis. among these two subspecies, b. animalis subsp. lactis is especially important because it is widely used in the manufacture of probiotic dairy products. the application of these microbes in the food industry demands fast, accurate and low cost methods to differentiate between species and strains. although various genotypic methods have been employed to discriminat ... | 2011 | 22365357 |
| preservation of functionality of bifidobacterium animalis subsp. lactis inl1 after incorporation of freeze-dried cells into different food matrices. | the aim of this work was to investigate how production and freeze-drying conditions of bifidobacterium animalis subsp. lactis inl1, a probiotic strain isolated from breast milk, affected its survival and resistance to simulated gastric digestion during storage in food matrices. the determination of the resistance of bifidobacteria to simulated gastric digestion was useful for unveiling differences in cell sensitivity to varying conditions during biomass production, freeze-drying and incorporatio ... | 2011 | 22265312 |
| the effect of lacto- and bifidobacteria compositions on the vaginal microflora in cases of intravaginal staphylococcosis. | the effect of intravaginal injection of lactobacillus casei imv b-7280, lactobacillus acidophilus imv b-7279, bifidobacterium animalis vkl and bifidobacterium animalis vkb strains in various compositions on the range of microflora of the urogenital tract on the model of experimental intravaginal staphylococcosis of mice was determined. it was established that under the influence of various compositions of these strains changes in microflora spectrum occurred the number of representatives of norm ... | 2012 | 23293831 |
| the science behind the probiotic strain bifidobacterium animalis subsp. lactis bb-12(®). | this review presents selected data on the probiotic strain bifidobacterium animalis subsp. lactis bb-12(®) (bb-12(®)), which is the world's most documented probiotic bifidobacterium. it is described in more than 300 scientific publications out of which more than 130 are publications of human clinical studies. the complete genome sequence of bb-12(®) has been determined and published. bb-12(®) originates from chr. hansen's collection of dairy cultures and has high stability in foods and as freeze ... | 2014 | 27682233 |
| discovery of novel small molecule modulators of clavibacter michiganensis subsp. michiganensis. | clavibacter michiganensis subsp. michiganensis (cmm) is a gram-positive seed-transmitted bacterial phytopathogen responsible for substantial economic losses by adversely affecting tomato production worldwide. a high-throughput, cell-based screen was adapted to identify novel small molecule growth inhibitors to serve as leads for future bactericide development. a library of 4,182 compounds known to be bioactive against saccharomyces cerevisiae was selected for primary screening against cmm wild-t ... | 2015 | 26539169 |
| comparative genomics of bifidobacterium animalis subsp. lactis reveals a strict monophyletic bifidobacterial taxon. | strains of bifidobacterium animalis subsp. lactis are extensively exploited by the food industry as health-promoting bacteria, although the genetic variability of members belonging to this taxon has so far not received much scientific attention. in this article, we describe the complete genetic makeup of the b. animalis subsp. lactis bl12 genome and discuss the genetic relatedness of this strain with other sequenced strains belonging to this taxon. moreover, a detailed comparative genomic analys ... | 2013 | 23645200 |
| identification of restriction-modification systems of bifidobacterium animalis subsp. lactis cncm i-2494 by smrt sequencing and associated methylome analysis. | bifidobacterium animalis subsp. lactis cncm i-2494 is a component of a commercialized fermented dairy product for which beneficial effects on health has been studied by clinical and preclinical trials. to date little is known about the molecular mechanisms that could explain the beneficial effects that bifidobacteria impart to the host. restriction-modification (r-m) systems have been identified as key obstacles in the genetic accessibility of bifidobacteria, and circumventing these is a prerequ ... | 2014 | 24743599 |
| bifidobacterium animalis subsp. lactis atcc 27673 is a genomically unique strain within its conserved subspecies. | many strains of bifidobacterium animalis subsp. lactis are considered health-promoting probiotic microorganisms and are commonly formulated into fermented dairy foods. analyses of previously sequenced genomes of b. animalis subsp. lactis have revealed little genetic diversity, suggesting that it is a monomorphic subspecies. however, during a multilocus sequence typing survey of bifidobacterium, it was revealed that b. animalis subsp. lactis atcc 27673 gave a profile distinct from that of the oth ... | 2013 | 23995933 |
| modulation of gut microbiota during probiotic-mediated attenuation of metabolic syndrome in high fat diet-fed mice. | structural disruption of gut microbiota and associated inflammation are considered important etiological factors in high fat diet (hfd)-induced metabolic syndrome (ms). three candidate probiotic strains, lactobacillus paracasei cncm i-4270 (lc), l. rhamnosus i-3690 (lr) and bifidobacterium animalis subsp. lactis i-2494 (ba), were individually administered to hfd-fed mice (10(8) cells day(-1)) for 12 weeks. each strain attenuated weight gain and macrophage infiltration into epididymal adipose tis ... | 2014 | 24936764 |
| comparative in vitro investigation of the cariogenic potential of bifidobacteria. | this study aimed to assess the in vitro cariogenic potential of some bifidobacterium species in comparison with caries-associated bacteria. | 2016 | 27475723 |
| bifidobacteria inhibit the growth of porphyromonas gingivalis but not of streptococcus mutans in an in vitro biofilm model. | there is growing interest in the use of probiotic bifidobacteria for enhancement of the therapy, and in the prevention, of oral microbial diseases. however, the results of clinical studies assessing the effects of bifidobacteria on the oral microbiota are controversial, and the mechanisms of actions of probiotics in the oral cavity remain largely unknown. in addition, very little is known about the role of commensal bifidobacteria in oral health. our aim was to study the integration of the probi ... | 2016 | 27061393 |
| metabolites of lactobacillus plantarum 2142 prevent oxidative stress-induced overexpression of proinflammatory cytokines in ipec-j2 cell line. | probiotics have already proven beneficial effects in the treatment of several intestinal infections, but the underlying mechanisms how the probiotics can affect responses of porcine ipec-j2 enterocytes to oxidative stress remained to be elucidated. the immunomodulatory effect of five bacterial strains (lactobacillus plantarum 2142, lactobacillus casei shirota, bifidobacterium animalis subsp. lactis bb-12, bacillus amyloliquefaciens cect 5940 and enterococcus faecium cect 4515) on 1 mm peroxide-t ... | 2012 | 22476971 |
| in vitro inhibition of eimeria tenella sporozoite invasion into host cells by probiotics. | the aim was to study the effects of probiotics isolated from the intestinal tract of livestock animals on eimeria tenella invasion into madin-darby bovine kidney (mdbk) cells in vitro. e. tenella sporozoites were purified and labeled with 5(6)-carboxyfluorescein diacetate n-succinimidyl ester before seeding on cell cultures, and invasion was evaluated by fluorescence microscopy. two protocols (a and b) were used. in protocol a, enterococcus faecium # 589 or lactobacillus salivarius subsp. saliva ... | 2016 | 27809987 |
| health-promoting properties exhibited by lactobacillus helveticus strains. | many strains belonging to lactobacilli exert a variety of beneficial health effects in humans and some of the bacteria are regarded as probiotic microorganisms. adherence and capabilities of colonization by lactobacillus strains of the intestinal tract is a prerequisite for probiotic strains to exhibit desired functional properties. the analysis conducted here aimed at screening strains of lactobacillus helveticus possessing a health-promoting potential. the molecular analysis performed, reveale ... | 2015 | 26601325 |
| rna-seq reveals transcriptomic interactions of bacillus subtilis natto and bifidobacterium animalis subsp. lactis in whole soybean solid-state co-fermentation. | bifidobacteria are anaerobes and are difficult to culture in conventional fermentation system. it was observed that bacillus subtilis natto enhanced growth of bifidobacterium animalis subsp. lactis v9 by about 3-fold in a whole soybean solid-state co-fermentation, in a non-anaerobic condition. for the purpose of understanding the metabolic interactions between bif. animalis subsp. lactis v9 and ba. subtilis natto, the transcriptome of bif. animalis subsp. lactis v9 and ba. subtilis natto was ana ... | 2015 | 26187824 |
| assessment of dietary supplementation with probiotics on performance, intestinal morphology and microflora of chickens infected with eimeria tenella. | we evaluated the effects of dietary supplementation with different preparations of probiotics on the performance of broiler chickens experimentally infected with 2 × 10(4) sporulated oocysts of eimeria tenella at 14 days of age. three hundred, day-old, cobb-500 chicks, as hatched, were separated into 10 equal groups with three replicates. two of the groups, one challenged with e. tenella oocysts and the other not, were given a basal diet and served as controls without medication. the other chall ... | 2012 | 22459110 |
| bacteroides fragilis metabolises exopolysaccharides produced by bifidobacteria. | bacteroides fragilis is the most frequent species at the human intestinal mucosal surface, it contributes to the maturation of the immune system although is also considered as an opportunistic pathogen. some bifidobacterium strains produce exopolysaccharides (eps), complex carbohydrate polymers that promote changes in the metabolism of b. fragilis when this microorganism grows in their presence. to demonstrate that b. fragilis can use eps from bifidobacteria as fermentable substrates, purified e ... | 2016 | 27418149 |
| an atp binding cassette transporter mediates the uptake of α-(1,6)-linked dietary oligosaccharides in bifidobacterium and correlates with competitive growth on these substrates. | the molecular details and impact of oligosaccharide uptake by distinct human gut microbiota (hgm) are currently not well understood. non-digestible dietary galacto- and gluco-α-(1,6)-oligosaccharides from legumes and starch, respectively, are preferentially fermented by mainly bifidobacteria and lactobacilli in the human gut. here we show that the solute binding protein (blg16bp) associated with an atp binding cassette (abc) transporter from the probiotic bifidobacterium animalis subsp. lactis b ... | 2016 | 27502277 |
| rna-stable-isotope probing shows utilization of carbon from inulin by specific bacterial populations in the rat large bowel. | knowledge of the trophisms that underpin bowel microbiota composition is required in order to understand its complex phylogeny and function. stable-isotope ((13)c)-labeled inulin was added to the diet of rats on a single occasion in order to detect utilization of inulin-derived substrates by particular members of the cecal microbiota. cecal digesta from fibruline-inulin-fed rats was collected prior to (0 h) and at 6, 12, 18 and 24 h following provision of the [(13)c]inulin diet. rna was extracte ... | 2014 | 24487527 |
| glucolytic fingerprinting reveals metabolic groups within the genus bifidobacterium: an exploratory study. | microorganisms of the genus bifidobacterium are inhabitants of diverse niches including the digestive tract of humans and animals. the species bifidobacterium adolescentis, bifidobacterium animalis, bifidobacterium bifidum, bifidobacterium breve and bifidobacterium longum have qualified presumption of safety status granted by efsa and several strains are considered probiotic, and are being included in functional dairy fermented products. in the present work we carried out a preliminary explorati ... | 2016 | 26839073 |
| isomer-specific consumption of galactooligosaccharides by bifidobacterial species. | prebiotics are nondigestible substrates that stimulate the growth of beneficial microbes in the human intestine. galactooligosaccharides (gos) are food ingredients that possess prebiotic properties, in particular, promoting the growth of bifidobacteria in situ. however, precise mechanistic details of gos consumption by bifidobacteria remain poorly understood. because gos are mixtures of polymers of different lengths and linkages, there is interest in determining which specific structures provide ... | 2013 | 24313277 |
| cholesterol-lowering probiotics: in vitro selection and in vivo testing of bifidobacteria. | thirty-four strains of bifidobacteria belonging to bifidobacterium adolescentis, bifidobacterium animalis, bifidobacterium bifidum, bifidobacterium breve, bifidobacterium longum, and bifidobacterium pseu-docatenulatum were assayed in vitro for the ability to assimilate cholesterol and for bile salt hydrolase (bsh) against glycocholic and taurodeoxycholic acids (gca and tdca). cholesterol assimilation was peculiar characteristic of two strains belonging to the species b. bifidum (b. bifidum mb 10 ... | 2013 | 23872958 |
| reduced th22 cell proportion and prevention of atopic dermatitis in infants following maternal probiotic supplementation. | in the randomized, controlled study probiotics in the prevention of allergy among children in trondheim (propact), maternal probiotic supplementation reduced the incidence of atopic dermatitis (ad) in the offspring. in the current study, we hypothesized that the effect was mediated by a shift in the t helper (th) cells in the children. | 2017 | 28346719 |
| effect of probiotic on innate inflammatory response and viral shedding in experimental rhinovirus infection - a randomised controlled trial. | ingestion of probiotics appears to have modest effects on the incidence of viral respiratory infection. the mechanism of these effects is not clear; however, there is evidence from animal models that the probiotic may have an effect on innate immune responses to pathogens. the purpose of this randomised, placebo-controlled study was to determine the effect of administration of bifidobacterium animalis subspecies lactis bl-04 on innate and adaptive host responses to experimental rhinovirus challe ... | 2017 | 28343401 |
| selective method for identification and quantification of bifidobacterium animalis subspecies lactis bb-12 (bb-12) from the gastrointestinal tract of healthy volunteers ingesting a combination probiotic of bb-12 and lactobacillus rhamnosus gg. | to develop a novel validated method for the isolation of bifidobacterium animalis ssp. lactis bb-12 (bb-12) from faecal specimens and apply it to studies of bb-12 and lactobacillus rhamnosus gg (lgg) recovered from the healthy human gastrointestinal (gi) tract. | 2017 | 28256070 |
| a proliferative probiotic bifidobacterium strain in the gut ameliorates progression of metabolic disorders via microbiota modulation and acetate elevation. | the gut microbiota is an important contributor to the worldwide prevalence of metabolic syndrome (ms), which includes obesity and diabetes. the anti-ms effects exerted by bifidobacterium animalis ssp. lactis gcl2505 (blag), a highly proliferative bifidobacterium strain in the gut, and b. longum ssp. longum jcm1217(t) (bloj) were comparatively examined. blag treatment reduced visceral fat accumulation and improved glucose tolerance, whereas bloj had no effect on these parameters. gut microbial an ... | 2017 | 28252037 |
| the effect of bifidobacterium animalis ssp. lactis hn019 on cellular immune function in healthy elderly subjects: systematic review and meta-analysis. | elderly people have increased susceptibility to infections and cancer that are associated with decline in cellular immune function. the objective of this work was to determine the efficacy of bifidobacterium (b.) animalis ssp. lactis hn019 (hn019) supplementation on cellular immune activity in healthy elderly subjects. we conducted a systematic review of medline and embase for controlled trials that reported polymorphonuclear (pmn) cell phagocytic capacity or natural killer (nk) cell tumoricidal ... | 2017 | 28245559 |
| spray-drying process preserves the protective capacity of a breast milk-derived bifidobacterium lactis strain on acute and chronic colitis in mice. | gut microbiota dysbiosis plays a central role in the development and perpetuation of chronic inflammation in inflammatory bowel disease (ibd) and therefore is key target for interventions with high quality and functional probiotics. the local production of stable probiotic formulations at limited cost is considered an advantage as it reduces transportation cost and time, thereby increasing the effective period at the consumer side. in the present study, we compared the anti-inflammatory capaciti ... | 2017 | 28233848 |
| safety of bifidobacterium animalis subsp. lactis (b. lactis) strain bb-12-supplemented yogurt in healthy children. | probiotics are live microorganisms that may provide health benefits to the individual when consumed in sufficient quantities. for studies conducted on health or disease endpoints on probiotics in the united states, the food and administration has required those studies to be conducted as investigational new drugs. this phase i, double-blinded, randomized, controlled safety study represents the first requirement of this pathway. the purpose of the study was to determine the safety of bifidobacter ... | 2017 | 28114246 |
| diversity of the subspecies bifidobacterium animalis subsp. lactis. | strains of bifidobacterium animalis subsp. lactis are well-known health-promoting probiotics used commercially. b. animalis subsp. lactis has been isolated from different sources, and little is known about animal isolates of this taxon. the aim of this study was to examine the genotypic and phenotypic diversity between b. animalis subsp. lactis strains different animal hosts including cameroon sheep, barbary sheep, okapi, mouflon, german shepard) and to compare to bb12, food isolates and the col ... | 2017 | 28108391 |
| early benefits of a starter formula enriched in prebiotics and probiotics on the gut microbiota of healthy infants born to hiv+ mothers: a randomized double-blind controlled trial. | the gut microbiota of infants is shaped by both the mode of delivery and the type of feeding. the gut of vaginally and cesarean-delivered infants is colonized at different rates and with different bacterial species, leading to differences in the gut microbial composition, which may persist up to 6 months. in a multicenter, randomized, controlled, double-blind trial conducted in south africa, we tested the effect of a formula supplemented with a prebiotic (a mixture of bovine milk-derived oligosa ... | 2016 | 28096702 |
| effect of probiotics on diarrhea in children with severe acute malnutrition: a randomized controlled study in uganda. | the aim of the study was to assess the effect of probiotics on diarrhea during in- and outpatient treatment of children with severe acute malnutrition (sam). | 2017 | 28079729 |
| effects of bifidobacterium animalis lactis hn019 (dr10tm), inulin, and micronutrient fortified milk on faecal dr10tm, immune markers, and maternal micronutrients among indonesian pregnant women. | maternal nutrition affects fetal growth and development. this study evaluates the effects of milk powder fortified with micronutrients, docosahexaenoic acid (dha), a prebiotic, and probiotic bifidobacterium animalis subsp. lactis hn019 dr10tm on the micronutrient status, as well as the presence of faecal probiotic and immune markers in pregnant women. | 2016 | 28027638 |
| comparative analysis of the rats' gut microbiota composition in animals with different ginsenosides metabolizing activity. | following oral intake of panax ginseng, major ginsenosides are metabolized to deglycosylated ginsenosides by gut microbiota before absorption into the blood. as the composition of gut microbiota varies between individuals, metabolic activities are significantly different. we selected 6 rats with low efficiency metabolism (lem) and 6 rats with high efficiency metabolism (hem) from 60 rats following oral administration of panax ginseng extract, and analyzed their gut microbiota composition using i ... | 2017 | 28025886 |
| use of probiotics as an adjuvant to sequential h. pylori eradication therapy: impact on eradication rates, treatment resistance, treatment-related side effects, and patient compliance. | to evaluate the effect of probiotics administered as an adjuvant to sequential helicobacter pylori (h. pylori) eradication therapy on treatment outcome and patient compliance. | 2017 | 28007678 |
| starter formula enriched in prebiotics and probiotics ensures normal growth of infants and promotes gut health: a randomized clinical trial. | prebiotics and probiotics exert beneficial effects by modulating gut microbiota and immune system. this study evaluates efficacy and safety of an infant formula containing bovine milk-derived oligosaccharides and bifidobacterium animalis ssp lactis (b. lactis) (cncm i-3446) on incidence of diarrhea and febrile infections during the first year of life (primary outcome). | 2017 | 28002391 |
| characterization of cinnamoyl esterases from different lactobacilli and bifidobacteria. | a high variety of plants that are used for food production contain esterified hydroxycinnamic acids. as their free forms display several benefits, like an enhanced absorption in human intestinal tract, anti-oxidative and anti-carcinogenic effects, an improved protein solubility and reduced discoloration, the microbial ability to cleave the ester bond is highly desired. in order to examine potential fermentation strains for this purpose, six different lactic acid bacteria and one bifidobacterial ... | 2017 | 27999938 |
| integrated role of bifidobacterium animalis subsp. lactis supplementation in gut microbiota, immunity, and metabolism of infant rhesus monkeys. | to investigate the impact of probiotic supplementation of infant formula on immune parameters, intestinal microbiota, and metabolism, five individually housed infant rhesus monkeys exclusively fed standard infant formula supplemented with probiotics (bifidobacterium animalis subsp. lactis hn019) from birth until 3 months of age were compared with five standard formula-fed and five breast-fed monkeys. anthropometric measurements, serum insulin, immune parameters, fecal microbiota, and metabolic p ... | 2017 | 27921083 |
| an exploratory investigation of endotoxin levels in novice long distance triathletes, and the effects of a multi-strain probiotic/prebiotic, antioxidant intervention. | gastrointestinal (gi) ischemia during exercise is associated with luminal permeability and increased systemic lipopolysaccharides (lps). this study aimed to assess the impact of a multistrain pro/prebiotic/antioxidant intervention on endotoxin unit levels and gi permeability in recreational athletes. thirty healthy participants (25 males, 5 females) were randomly assigned either a multistrain pro/prebiotic/antioxidant (lab⁴anti; 30 billion cfu·day(-1) containing 10 billion cfu·day(-1)lactobacill ... | 2016 | 27869661 |
| effect of bifidobacterium animalis ssp. lactis gcl2505 on visceral fat accumulation in healthy japanese adults: a randomized controlled trial. | bifidobacterium animalis ssp. lactis gcl2505 (b. lactis gcl2505) is able to survive passage through the intestine and then proliferate, leading to an increase in the amount of gut bifidobacteria. in the present study, we evaluated the impact of b. lactis gcl2505 on abdominal visceral fat storage in overweight and mildly obese japanese adults. this clinical study was a double-blind, randomized, placebo-controlled, parallel-group comparative trial performed for 12 weeks. healthy japanese subjects ... | 2016 | 27867803 |
| in vitro fermentation of different fructo-oligosaccharides by bifidobacterium strains for the selection of synbiotic combinations. | the use of selected probiotics, prebiotics and/or synbiotics, constitute an interesting dietary strategy for intestinal microbiota modulation in case of dysbiosis. species of the genus bifidobacterium are among the most currently used probiotics for human consumption since they have shown beneficial effects in the prevention and treatment of some disorders. bifidobacteria are saccharolytic microorganisms, but their ability to use different carbohydrates varies among strains. in this study, we in ... | 2017 | 27866040 |
| genotyping by pcr and high-throughput sequencing of commercial probiotic products reveals composition biases. | recent advances in microbiome research have brought renewed focus on beneficial bacteria, many of which are available in food and dietary supplements. although probiotics have historically been defined as microorganisms that convey health benefits when ingested in sufficient viable amounts, this description now includes the stipulation "well defined strains," encompassing definitive taxonomy for consumer consideration and regulatory oversight. here, we evaluated 52 commercial dietary supplements ... | 2016 | 27857709 |
| orally administered multispecies probiotic formulations to prevent uro-genital infections: a randomized placebo-controlled pilot study. | the aim of this study was to evaluate in the vagina of 60 pre-menopausal women the detection of orally administered multispecies probiotic formulations showing anti-microbial properties in test in vitro. | 2017 | 27826653 |
| effect of bifidobacterium animalis subsp. lactis gcl2505 on the physiological function of intestine in a rat model. | bifidobacterium animalis ssp. lactis gcl2505 has been shown to proliferate in the human intestine. the intestinal dynamics and physiological effects of gcl2505 as well as the mechanism underlying proliferation in the gut were investigated. gcl2505 showed markedly higher resistance to free bile acids (cholic and deoxycholic acids) than other bifidobacterial species. the intestinal dynamics of gcl2505 and b. longum ssp. longum jcm1217(t) was compared. the level of b. animalis ssp. lactis in the gc ... | 2016 | 27826427 |
| modulation of the bifidobacterial communities of the dog microbiota by zeolite. | during last decades canine health and well being is becoming an important issue for human owners. in dogs, several factors including diet, pathogenic bacterial and stress conditions can affect the composition of the gut microbiota. in this study, we evaluated the effect of dietary chabazitic zeolitite (cz) supplementation on the contribution of bifidobacteria to the fecal microbiota in training hunting dogs. fecal microbiota cataloging based on 16s rrna microbial profiling analyses highlighted a ... | 2016 | 27713735 |
| influence of the addition of lactobacillus acidophilus la-05, bifidobacterium animalis subsp. lactis bb-12 and inulin on the technological, physicochemical, microbiological and sensory features of creamy goat cheese. | the effects of the addition of lactobacillus acidophilus la-05, bifidobacterium animalis subsp. lactis bb-12 and inulin on the quality characteristics of creamy goat cheese during refrigerated storage were evaluated. the manufactured cheeses included the addition of starter culture (lactococcus lactis subsp. lactis and lactococcus lactis subsp. cremoris - r-704) (cc); starter culture, l. acidophilus la-05 and inulin (cla); starter culture, b. lactis bb-12 and inulin (cbb); or starter culture, l. ... | 2016 | 27711907 |
| the different effects of probiotics treatment on salmonella-induced interleukin-8 response in intestinal epithelia cells via pi3k/akt and nod2 expression. | salmonella spp. remains a major public health problem for the whole world. intestinal epithelial cells serve as an essential component of the innate mucosal immune system to defend against salmonella infection. a substantial amount of evidence has accumulated that probiotics can regulate interleukin 8 (il-8) involved in innate immunity. however, the exact effect of probiotics on epithelial il-8 response to salmonella infection is not well understood. therefore, we investigated the action of prob ... | 2016 | 27680208 |
| benefits of bifidobacterium animalis subsp. lactis probiotic in experimental periodontitis. | this study evaluates effects of topical administration of probiotic bacteria of the genus bifidobacterium on experimental periodontitis (ep) in rats. | 2017 | 27660886 |
| impact of gluten-friendly bread on the metabolism and function of in vitro gut microbiota in healthy human and coeliac subjects. | the main aim of this paper was to assess the in vitro response of healthy and coeliac human faecal microbiota to gluten-friendly bread (gfb). thus, gfb and control bread (cb) were fermented with faecal microbiota in ph-controlled batch cultures. the effects on the major groups of microbiota were monitored over 48 h incubations by fluorescence in situ hybridisation. short-chain fatty acids (scfas) were measured by high-performance liquid chromatography (hplc). furthermore, the death kinetics of l ... | 2016 | 27632361 |
| chemical and structural characterization of pholiota nameko extracts with biological properties. | edible mushrooms including pholiota nameko are excellent sources of extractable bioactive compounds with much to explore. enzymatic extractions with cellulase and viscozyme were responsible for highest extraction yields (67-77%). no strong antioxidant activity was observed although extracts were able to scavenge abts(+) and oh(+). potential prebiotic activity was observed in all extracts, some increasing 1.4-2 log cycles of lactobacillus acidophilus la-5 and bifidobacterium animalis bb12. 30-50% ... | 2017 | 27596407 |
| a peptidome-based phylogeny pipeline reveals differential peptides at the strain level within bifidobacterium animalis subsp. lactis. | bifidobacteria are gut commensal microorganisms belonging to the actinobacteria group. some specific strains of bifidobacterium animalis subsp. lactis are used in functional foods as they are able to exert health-promoting effects in the human host. due to the limited genetic variability within this subspecies, it is sometimes difficult for a manufacturer to properly track its strain once included in dairy products or functional foods. in this paper, we present a peptidome-based analysis in whic ... | 2016 | 27554155 |
| systematic review and meta-analysis: multi-strain probiotics as adjunct therapy for helicobacter pylori eradication and prevention of adverse events. | eradication rates with triple therapy for helicobacter pylori infections have currently declined to unacceptable levels worldwide. newer quadruple therapies are burdened with a high rate of adverse events. whether multi-strain probiotics can improve eradication rates or diminish adverse events remains uncertain. | 2016 | 27536365 |
| screening of cholesterol-lowering bifidobacterium from guizhou xiang pigs, and evaluation of its tolerance to oxygen, acid, and bile. | cardiovascular and cerebrovascular diseases seriously harm human health, and bifidobacterium is the most beneficial probiotic in the gastrointestinal tract of humans. this work aimed to screen cholesterol-lowering bifidobacterium from guizhou xiang pig and evaluate its tolerance to oxygen, acid, and bile. twenty-seven aerotolerant strains with similar colony to bifidobacterium were isolated through incubation at 37℃ in 20% (v/v) co2-80% (v/v) atmospheric air by using mupirocin lithium modified m ... | 2016 | 27499662 |
| in vitro gastrointestinal resistance of lactobacillus acidophilus la-5 and bifidobacterium animalis bb-12 in soy and/or milk-based synbiotic apple ice creams. | the viability and resistance to simulated gastrointestinal (gi) conditions of lactobacillus acidophilus la-5 and bifidobacterium animalis bb-12 in synbiotic ice creams, in which milk was replaced by soy extract and/or whey protein isolate (wpi) with inulin, were investigated. the ice creams were showed to be satisfactory vehicles for la-5 and bb-12 (populations around 7.5logcfu/g), even after the whole storage period (84days/-18°c). in all formulations, the propidium monoazide qpcr (pma-qpcr) an ... | 2016 | 27387254 |
| effect of a ropy exopolysaccharide-producing bifidobacterium animalis subsp. lactis strain orally administered on dss-induced colitis mice model. | exopolysaccharide (eps)-producing bifidobacteria, particularly bifidobacterium animalis subsp. lactis strains, are used in the functional food industry as promising probiotics with purported beneficial effects. we used three isogenic strains of b. animalis subsp. lactis, with different eps producing phenotypes (mucoid-ropy and non-ropy), in order to determine their capability to survive the murine gastrointestinal tract transit, as well as to evaluate their role in improving clinical outcomes in ... | 2016 | 27375589 |
| effects of the food manufacturing chain on the viability and functionality of bifidobacterium animalis through simulated gastrointestinal conditions. | the viability and functionality of probiotics may be influenced by industrial production processes resulting in a decrease in probiotic efficiency that benefit the health of humans. this study aimed to investigate the probiotic characteristics of bifidobacterium strains isolated from fecal samples of healthy thai infants. in the present work, three local strains (bf014, bf052, and bh053) belonging to bifidobacterium animalis showed a great resistance against conditions simulating the gastrointes ... | 2016 | 27333286 |
| effect of bifidobacterium upon clostridium difficile growth and toxicity when co-cultured in different prebiotic substrates. | the intestinal overgrowth of clostridium difficile, often after disturbance of the gut microbiota by antibiotic treatment, leads to c. difficile infection (cdi) which manifestation ranges from mild diarrhea to life-threatening conditions. the increasing cdi incidence, not only in compromised subjects but also in traditionally considered low-risk populations, together with the frequent relapses of the disease, has attracted the interest for prevention/therapeutic options. among these, probiotics, ... | 2016 | 27242753 |
| bifidobacterium animalis ssp. lactis cncm-i2494 restores gut barrier permeability in chronically low-grade inflamed mice. | growing evidence supports the efficacy of many probiotic strains in the management of gastrointestinal disorders associated with deregulated intestinal barrier function and/or structure. in particular, bifidobacteria have been studied for their efficacy to both prevent and treat a broad spectrum of animal and/or human gut disorders. the aim of the current work was thus to evaluate effects on intestinal barrier function of bifidobacterium animalis ssp. lactis cncm-i2494, a strain used in fermente ... | 2016 | 27199937 |
| effects of synbiotic fermented milk containing lactobacillus acidophilus la-5 and bifidobacterium animalis ssp. lactis bb-12 on the fecal microbiota of adults with irritable bowel syndrome: a randomized double-blind, placebo-controlled trial. | we conducted a randomized double-blind, placebo-controlled multicentric study to investigate the influence of a synbiotic fermented milk on the fecal microbiota composition of 30 adults with irritable bowel syndrome (ibs). the synbiotic product contained lactobacillus acidophilus la-5, bifidobacterium animalis ssp. lactis bb-12, streptococcus thermophilus, and dietary fiber (90% inulin, 10% oligofructose), and a heat-treated fermented milk without probiotic bacteria or dietary fiber served as pl ... | 2016 | 27157575 |
| identification of surface-associated proteins of bifidobacterium animalis ssp. lactis klds 2.0603 by enzymatic shaving. | bifidobacteria are commensal microorganisms of the human and animal intestinal tract, and their surface proteins can mediate bacterial communication and chemical sensing in the environment, as well as facilitate interactions between bacteria and the host. however, a systematic study of the outer surface-associated proteome of bifidobacteria has not been undertaken. in the present study, the proteins located on the surface of bifidobacterium animalis ssp. lactis klds 2.0603 were systematically id ... | 2016 | 27132091 |
| oligosaccharides released from milk glycoproteins are selective growth substrates for infant-associated bifidobacteria. | milk, in addition to nourishing the neonate, provides a range of complex glycans whose construction ensures a specific enrichment of key members of the gut microbiota in the nursing infant, a consortium known as the milk-oriented microbiome. milk glycoproteins are thought to function similarly, as specific growth substrates for bifidobacteria common to the breast-fed infant gut. recently, a cell wall-associated endo-β-n-acetylglucosaminidase (endobi-1) found in various infant-borne bifidobacteri ... | 2016 | 27084007 |
| influence of 6 different intestinal bacteria on beltsville small white turkey semen. | the turkey industry relies totally on artificial insemination to continue and improve production. if something compromises the insemination process, such as contaminated semen, it becomes a detrimental loss to the industry. bacteria have been found in broiler breeder males to reduce sperm motility. the sperm quality index (sqi) is a quick method to determine avian sperm motility using the sperm quality analyzer (sqa). therefore, the objective of this study was to determine if bacteria have an ef ... | 2016 | 27081196 |
| cd19 lymphocyte proliferation induced by bifidobacterium animalis subsp. lactis in c57bl/6 mice experimentally infected with toxoplasma gondii. | toxoplasmosis is frequently acquired through the oral route by the ingestion of cysts or oocysts of toxoplasma gondii. once ingested, the parasites penetrate the intestinal epithelial cells and rapidly disseminate to all organs in the host. during t. gondii infection, the intestinal microbiota plays an important role in stimulating a protective immune response against the parasite. in this sense the use of probiotics is worthy of note since they are live microorganisms that have beneficial effec ... | 2016 | 27074320 |
| probiotic strain bifidobacterium animalis subsp. lactis cect 8145 reduces fat content and modulates lipid metabolism and antioxidant response in caenorhabditis elegans. | recently, microbial changes in the human gut have been proposed as a possible cause of obesity. therefore, modulation of microbiota through probiotic supplements is of great interest to support obesity therapeutics. the present study examines the functional effect and metabolic targets of a bacterial strain, bifidobacterium animalis subsp. lactis cect 8145, selected from a screening in caenorhabditis elegans. this strain significantly reduced total lipids (40.5% ± 2.4) and triglycerides (27.6% ± ... | 2016 | 27054371 |
| phenolic acid degradation potential and growth behavior of lactic acid bacteria in sunflower substrates. | sunflower flour provides a high content of protein with a well-balanced amino acid composition and is therefore regarded as an attractive source for protein. the use for human nutrition is hindered by phenolic compounds, mainly chlorogenic acid, which can lead under specific circumstances to undesirable discolorations. in this study, growth behavior and degradation ability of chlorogenic acid of four lactic acid bacteria were explored. data suggested that significant higher fermentation performa ... | 2016 | 27052717 |
| a prebiotic mixture improved lactobacillus acidophilus and bifidobacterium animalis gastrointestinal in vitro resistance in petit-suisse. | the survival of two probiotic strains -lactobacillus acidophilus la-5 and bifidobacterium animalis bb-12 - incorporated into probiotic (pc) and into synbiotic (sc, with inulin + fructooligosaccharides, respectively, at 7.5 and at 2.5 g per 100 g) petit-suisse cheese was investigated in the beginning (day 1) and at the end (28 days) of storage at 4 °c when the food products were subjected to in vitro gastrointestinal simulated assays. species-specific quantitative real time pcr (qpcr) combined wi ... | 2016 | 27112363 |
| probiotics and respiratory and gastrointestinal tract infections in finnish military conscripts - a randomised placebo-controlled double-blinded study. | military conscripts are susceptible to respiratory and gastrointestinal tract infections. in previous studies probiotics have shown potency to reduce upper respiratory and gastrointestinal infections. the aim was to study whether probiotic intervention has an impact on seasonal occurrence of upper respiratory and gastrointestinal infections in two different conscript groups. in a randomised, double-blinded, placebo controlled study (https://clinicaltrials.gov nct01651195), a total of 983 healthy ... | 2016 | 27048835 |
| effect of aqueous extract of the seaweed gracilaria domingensis on the physicochemical, microbiological, and textural features of fermented milks. | the effects of the gracilaria domingensis seaweed aqueous extract in comparison with gelatin on the physicochemical, microbial, and textural characteristics of fermented milks processed with the mixed culture sab 440 a, composed of streptococcus thermophilus, lactobacillus acidophilus, and bifidobacterium animalis ssp. lactis, were investigated. the addition of g. domingensis aqueous extract did not affect ph, titratable acidity, and microbial viability of fermented milks when compared with the ... | 2016 | 26989840 |
| comparative experimental investigation on the efficacy of mono- and multiprobiotic strains in non-alcoholic fatty liver disease prevention. | to investigate the efficacy of different probiotic strains, their combinations and forms (alive or lyophilized) in nonalcoholic fatty liver disease (nafld) prevention. | 2016 | 26976285 |
| supplementation of xylitol-containing chewing gum with probiotics: a double blind, randomised pilot study focusing on saliva flow and saliva properties. | the aim of this study was to investigate the impact of daily chewing, for 12 weeks, of 2 different probiotic gums compared with placebo on saliva flow rate, saliva iga levels and saliva ph. the intervention study included 54 adult volunteers with hyposalivation in a double-blind, randomised and placebo-controlled design with three parallel groups. volunteers were randomly assigned to 3 different groups: subjects in group a (n = 19) were given placebo chewing gum, group b (n = 17) received bifido ... | 2016 | 26913493 |
| probiotic yogurt culture bifidobacterium animalis subsp. lactis bb-12 and lactobacillus acidophilus la-5 modulate the cytokine secretion by peripheral blood mononuclear cells from patients with ulcerative colitis. | there are some evidences for the immunomodulation disorders in the response to intestinal microbiota in inflammatory bowel disease. yogurt is a fermented milk product made with a starter culture consisting of different probiotics which could be colonized in intestine. however, the role of probiotics in the aetiopathogenesis of ulcerative colitis (uc) has not been clarified. to determine how the immune system responds to these bacteria this study was planned. | 2016 | 26909690 |
| suppression subtractive hybridisation and real-time pcr for strain-specific quantification of the probiotic bifidobacterium animalis ban in broiler feed. | to ensure quality management during the production processes of probiotics and for efficacy testing in vivo, accurate tools are needed for the identification and quantification of probiotic strains. in this study, a strain-specific qpcr assay based on suppression subtractive hybridisation (ssh) for identifying unique sequences, was developed to quantify the strain bifidobacterium animalis ban in broiler feed. seventy potential ban specific sequences were obtained after ssh of the ban genome, wit ... | 2016 | 26883620 |
| the one-pot multienzyme (opme) synthesis of human blood group h antigens and a human milk oligosaccharide (hmos) with highly active thermosynechococcus elongates α1-2-fucosyltransferase. | a novel α1-2-fucosyltransferase from thermosynechococcus elongatus bp-1 (te2ft) with high fucosyltransferase activity and low donor hydrolysis activity was discovered and characterized. it was used in an efficient one-pot multienzyme (opme) fucosylation system for the high-yield synthesis of human blood group h antigens containing β1-3-linked galactosides and an important human milk oligosaccharide (hmos) lacto-n-fucopentaose i (lnfp i) on preparative and gram scales. lnfp i was shown to be sele ... | 2016 | 26864394 |
| consumption of bifidobacterium animalis subsp. lactis bb-12 impacts upper respiratory tract infection and the function of nk and t cells in healthy adults. | probiotics can modulate immunity and reduce upper respiratory tract infections (urti) in humans; however few studies have examined both outcomes in the same trial. the goal of the current study was to investigate the effect of bifidobacterium animalis subsp. lactis bb-12, on natural killer (nk) and t-cell function in conjunction with self-reported cold/flu outcomes in healthy adults. | 2016 | 26821116 |
| complete genome sequence of bifidobacterium animalis subsp. lactis klds 2.0603, a probiotic strain with digestive tract resistance and adhesion to the intestinal epithelial cells. | bifidobacterium animalis subsp. lactis klds 2.0603 (abbreviated as klds 2.0603) is a probiotic strain isolated from the feces of an adult human. previous studies showed that klds 2.0603 has a high resistance to simulated digestive tract conditions and a high ability to adhere to intestinal epithelial cells (caco-2). these two characteristics are essential requirements for the selection of probiotic bacteria. to explore the stress resistance mechanism to the digestive tract environment and the ad ... | 2016 | 26795356 |
| antimicrobial potential of commercial silver nanoparticles and the characterization of their physical properties toward probiotic bacteria isolated from fermented milk products. | the application of nanotechnology in the agriculture and food sector is relatively recent compared to its usage in drug delivery or pharmaceuticals. therefore, this paper presents a study of the effect of silver nanoparticles on probiotic bacteria based on the example of lactobacillus acidophilus la-5, bifidobacterium animalis subsp. lactis bb-12 and streptococcus thermophilus st-y31 isolated from fermented milk products. probiotic bacteria are one of the most crucial groups of bacteria for the ... | 2016 | 26766747 |
| clinical application of probiotics in type 2 diabetes mellitus: a randomized, double-blind, placebo-controlled study. | type 2 diabetes has been associated with dysbiosis and one of the possible routes to restore a healthy gut microbiota is by the regular ingestion of probiotics. we aimed to investigate the effects of probiotics on glycemic control, lipid profile, inflammation, oxidative stress and short chain fatty acids in t2d. | 2017 | 26732026 |
| using physical approaches for the attenuation of lactic acid bacteria in an organic rice beverage. | a wild strain of lactobacillus plantarum, isolated from an italian sourdough, was inoculated in an organic rice drink; however, it caused a strong acidification. thus, it was preliminary processed through homogenization (single or multiple passes) or sonication (us) and then inoculated in the beverage. the samples were stored at 4 °c and analyzed to assess ph, production of lactic acid, viable count and sensory scores. a us-2-step process (power, 80%) could control acidification; viability and s ... | 2016 | 26678123 |
| gut microbiota analysis reveals a marked shift to bifidobacteria by a starter infant formula containing a synbiotic of bovine milk-derived oligosaccharides and bifidobacterium animalis subsp. lactis cncm i-3446. | non-digestible milk oligosaccharides were proposed as receptor decoys for pathogens and as nutrients for beneficial gut commensals like bifidobacteria. bovine milk contains oligosaccharides, some of which are structurally identical or similar to those found in human milk. in a controlled, randomized double-blinded clinical trial we tested the effect of feeding a formula supplemented with a mixture of bovine milk-derived oligosaccharides (bmos) generated from whey permeate, containing galacto-oli ... | 2016 | 26626365 |
| consumption of bifidobacterium animalis subsp. lactis bb-12 in yogurt reduced expression of tlr-2 on peripheral blood-derived monocytes and pro-inflammatory cytokine secretion in young adults. | probiotic bacteria modulate immune parameters and inflammatory outcomes. emerging evidence demonstrates that the matrix used to deliver probiotics may influence the efficacy of probiotic interventions in vivo. the aims of the current study were to evaluate (1) the effect of one species, bifidobacterium animalis subsp. lactis bb-12 at a dose of log10 ± 0.5 cfus/day on immune responses in a randomized, partially blinded, 4-period crossover, free-living study, and (2) whether the immune response to ... | 2017 | 26621631 |
| short- and long-term dynamics in the intestinal microbiota following ingestion of bifidobacterium animalis subsp. lactis gcl2505. | bifidobacterium animalis subsp. lactis gcl2505 (b. lactis gcl2505) is able to survive passage through the intestines and proliferate. the daily dynamics of the intestinal bifidobacteria following ingestion of probiotics are not yet clear. moreover, the effects of long-term ingestion of probiotics on the intestinal microbiota have not been well studied. two experiments were performed in the present study. in experiment 1, 53 healthy female volunteers received b. lactis gcl2505; b. bifidum gcl2080 ... | 2015 | 26594607 |
| proteolysis in goat "coalho" cheese supplemented with probiotic lactic acid bacteria. | this study aimed to analyse the proteolytic effects of adding isolated and combined probiotic strains to goat "coalho" cheese. the cheeses were: qs - with culture start, composed by lactococcus lactis subsp. lactis and l. lactis subsp. cremoris (r704); qla - with lactobacillus acidophilus (la-5); qlp - with lactobacillus paracasei subsp. paracasei (l. casei 01); qb - with bifidobacterium animalis subsp. lactis (bb 12); and qc, co-culture with the three probiotic microorganisms. the cheeses were ... | 2016 | 26593502 |
| probiotic supplementation influences faecal short chain fatty acids in infants at high risk for eczema. | the composition of the gut microbiota plays a role in the development of allergies. based on the immunomodulating capacities of bacteria, various studies have investigated the potential role for probiotics in the prevention of childhood eczema. in a previous study we have shown that significantly less children developed eczema after probiotic supplementation (bifidobacterium bifidum w23, bifidobacterium animalis subsp. lactis w52 and lactococcus lactis w58, ecologic(®)panda) at three months of a ... | 2015 | 26565082 |
| the gh5 1,4-β-mannanase from bifidobacterium animalis subsp. lactis bl-04 possesses a low-affinity mannan-binding module and highlights the diversity of mannanolytic enzymes. | β-mannans are abundant and diverse plant structural and storage polysaccharides. certain human gut microbiota members including health-promoting bifidobacterium spp. catabolize dietary mannans. little insight is available on the enzymology of mannan deconstruction in the gut ecological niche. here, we report the biochemical properties of the first family 5 subfamily 8 glycoside hydrolase (gh5_8) mannanase from the probiotic bacterium bifidobacterium animalis subsp. lactis bl-04 (blman5_8). | 2015 | 26558435 |
| intestinal microbiota in neonates requiring urgent surgery: assessing the role of probiotics using fecal dna sequencing. | to assess the impact of urgent surgery on neonates and the value of an orally administered probiotic preparation of bifidobacterium animalis subsp. lactis lkm512 (lkm) using fecal dna sequencing to analyze intestinal microbiota. | 2016 | 26516074 |
| the longitudinal effect of a multi-strain probiotic on the intestinal bacterial microbiota of neonatal foals. | the microbiota plays a key role in health and disease. probiotics are a potential way to therapeutically modify the intestinal microbiota and prevent disease. | 2016 | 26509834 |