| antigenic structure and variation of canine parvovirus type-2, feline panleukopenia virus, and mink enteritis virus. | the antigenic structure and variation of canine parvovirus type-2 (cpv), feline panleukopenia virus (fpv), mink enteritis virus (mev), and a closely related virus of raccoons (rpv) was investigated using a panel of 13 monoclonal antibodies (mab) formed against cpv and 8 mab formed against fpv. each mab both neutralized and inhibited the hemagglutination of the homologous virus. all mab tested immunoprecipitated the two capsid proteins. five mab were specific for the cpv isolates and one reacted ... | 1983 | 6194613 |
| expression of canine parvovirus-beta-galactosidase fusion proteins in escherichia coli. | cloned dna fragments encoding portions of canine parvovirus (cpv) structural proteins were inserted into plasmid expression vectors. these plasmids expressed cpv-beta-galactosidase fusion proteins under the transcriptional control of the escherichia coli lac promoter-operator. the fusion proteins were purified and used to immunize rabbits. rabbit antibodies raised against these fusion proteins were shown to immunoprecipitate authentic cpv structural proteins from infected cell extracts. this dem ... | 1984 | 6208084 |
| experimental canine parvovirus infection in dogs. | in specific pathogen-free dogs, clinical signs of experimental canine parvovirus infection were mild, inconsistent and transient. clinical signs were more pronounced in conventionally-raised dogs, but the severe disease reported in field cases was not reproduced in either group. a pronounced plasma viremia occurred on the 2nd to 4th day post-infection (d.p.i.) in dogs challenged oronasally. antibody was detectable on the 5th d.p.i. marked pyrexia was rare, but a significant temperature rise usua ... | 1982 | 6211333 |
| hemagglutination by canine parvovirus: serologic studies and diagnostic applications. | conditions for canine parvoviral hemagglutination (ha) and hemagglutination-inhibition (hi) reactions were defined. the ha phenomena were used to differentiate canine parvovirus (cpv) from feline panleukopenia virus (fpv), mink enteritis virus (mev), and minute virus of canines. serologic comparisons of the cpv, fpv, and mev by ha-hi and serum-neutralization tests indicated that cpv, fpv, and mev were antigenically similar but were different from minute virus of canines. diagnostic application o ... | 1980 | 6250432 |
| canine parvovirus: update. | | 1980 | 6254222 |
| origin of canine parvovirus. | | 1980 | 6254227 |
| canine parvovirus: safety and efficacy of attenuated feline panleucopenia vaccine. | | 1980 | 6254234 |
| canine viral enteritis: prevalence of parvo-, corona- and rotavirus infections in dogs in the netherlands. | after a brief review of the present knowledge about canine viral enteritis, the role played by parvoviral, coronaviral and rotaviral infections in contagious diarrhoea in dogs in the netherlands is discussed. for this purpose a serologic survey, pathologic findings in dogs, and the demonstration of parvoviral antigen with an immunofluorescence test and with a newly developed haemadsorption-elution-haemagglutination assay (heha) are presented. it is concluded that infections with canine parvoviru ... | 1980 | 6255629 |
| fpl vaccine and canine parvovirus. | | 1980 | 6255666 |
| fpl vaccine and canine parvovirus. | | 1980 | 6255667 |
| canine parvovirus vaccination. | | 1980 | 6258042 |
| [detection of antibodies against the canine parvovirus in healthy dogs with indirect immunofluorescence technique (author's transl)]. | | 1981 | 6260454 |
| comparison of canine parvovirus with mink enteritis virus by restriction site mapping. | the genomes of canine parvovirus and mink enteritis virus were compared by restriction enzyme analysis of their replicative-form dnas. of 79 mapped sites, 68, or 86%, were found to be common for both types of dna, indicating that canine parvovirus and mink enteritis virus are closely related viruses. whether they evolved from a common precursor or whether canine parvovirus is derived from mink enteritis virus, however, cannot be deduced from our present data. | 1981 | 6264109 |
| antigenic differences between canine parvovirus and feline panleucopenia virus. | | 1980 | 6266119 |
| canine viruses and multiple sclerosis. | serum and cerebrospinal fluid from multiple sclerosis (ms) patients and control subjects were tested and compared for presence and titer of neutralizing antibody against the most common canine viruses. canine viruses included canine distemper virus (cdv), canine adenovirus 1 (cav-1), canine parainfluenza virus (cpiv), canine herpesvirus (chv), canine coronavirus (ccv), and canine parvovirus (cpv). neutralizing titers against measles virus (mv) and human adenovirus 8 (ha8) were also tested. signi ... | 1981 | 6267515 |
| toxigenic clostridium perfringens from a parvovirus-infected dog. | a strain of clostridium perfringens, type a, has been isolated from the intestine of a dog which died from parvovirus infection. this clostridium strain produces a toxin which can be detected by counterimmunoelectrophoresis, using c. difficile antitoxin, and produces cytotoxicity in wi-38 cell culture. cytopathology can be blocked by c. difficile antitoxin. its role in canine parvovirus infection is unknown. | 1981 | 6277989 |
| dog response to inactivated canine parvovirus and feline panleukopenia virus vaccines. | inactivated canine parvovirus (cpv) and inactivated feline panleukopenia virus (fpv) vaccines were evaluated in dogs. maximal serologic response occurred within 1-2 weeks after vaccination. antibody titers then declined rapidly to low levels that persisted at least 20 weeks. immunity to cpv, defined as complete resistance to infection, was correlated with serum antibody titer and did not persist longer than 6 weeks after vaccination with inactivated virus. however, protection against generalized ... | 1982 | 6279359 |
| successful experimental challenge of dogs with canine parvovirus-2. | withholding food from dogs for 24 hours prior to, and for 48 hours following oral challenge with a gut mucosal homogenate of canine parvovirus-2, was a successful means of reproducing gastroenteric signs of canine parvovirus-2 infection. twenty-one of 24 dogs, which had previously received various vaccine preparations of mink enteritis virus or were unvaccinated, and which were starved at challenge, developed soft or liquid feces with large or without large clots of mucus. altered feces were mos ... | 1982 | 6280819 |
| the failure of an inactivated mink enteritis virus vaccine in four preparations to provide protection to dogs against challenge with canine parvovirus-2. | four experimental vaccine preparations comprising a strain of mink enteritis virus inactivated by either formalin or beta-propiolactone, and either adjuvanted or nonadjuvanted, failed to stimulate a consistent serum antibody response in 20 vaccinated dogs and failed to protect all but one of these dogs against oral challenge with canine parvovirus-2. | 1982 | 6280820 |
| field evaluation of a canine parvovirus vaccination program, using feline origin modified live virus vaccine. | antibody titers measured by hemagglutination inhibition testing were determined in previously vaccinated dogs at the time of booster vaccination and 2 weeks later. all vaccines consisted of modified live panleukopenia virus. the booster injection was administered approximately 6 months after the initial parvovirus vaccination series was given. fecal and serum specimens were collected immediately before and 2 weeks after administration of the booster vaccine for hemagglutination and hemagglutinat ... | 1982 | 6284689 |
| raccoons are not susceptible to canine parvovirus. | | 1982 | 6290438 |
| experiments with a homologous, inactivated canine parvovirus vaccine in vaccination programmers for dogs. | the significance of canine parvovirus (cpv) infections as a permanent threat susceptible dogs, in particular pups, made the authors develop three liquid homologous inactivated adjuvant cpv vaccines that were compatible with existing canine vaccines and could be incorporated in current vaccination programmes. on vaccine (kavak parvo) contained only the cpv component, the second product (kavak i-lp) also contained two inactivated leptospiral antigens, and the third vaccine (kavak i-hlp) contained ... | 1982 | 6293155 |
| evaluation of a killed feline panleukopenia virus vaccine against canine parvoviral enteritis in dogs. | immunogenic potency of a killed feline panleukopenia virus vaccine against canine parvoviral enteritis in dogs was examined. the vaccine elicited hemagglutination-inhibition antibodies to canine parvovirus (cpv) in all of the 72 dogs which were vaccinated. the vaccine was protective in dogs against both experimentally induced and naturally occurring cpv-induced disease. by statistical analysis, 4 weeks was found to be the optimal spacing between 2 vaccinal doses resulting in hemagglutination-inh ... | 1982 | 6299140 |
| use of modified live feline panleukopenia virus vaccine to immunize dogs against canine parvovirus. | modified live feline panleukopenia virus (fplv) vaccine protected dogs against canine parvovirus (cpv) infection. however, unlike the long-lived (greater than or equal to 20-month) immunity engendered by cpv infection, the response of dogs to living fplv was variable. doses of fplv (snow leopard strain) in excess of 10(5.7) tcid50 were necessary for uniform immunization; smaller inocula resulted in decreased success rates. the duration of immunity, as measured by the persistence of hemagglutinat ... | 1983 | 6299142 |
| response of mink, skunk, red fox and raccoon to inoculation with mink virus enteritis, feline panleukopenia and canine parvovirus and prevalence of antibody to parvovirus in wild carnivores in ontario. | mink virus enteritis, feline panleukopenia and canine parvovirus-2 were inoculated separately into groups of raccoon, mink, red fox and striped skunk. raccoons were highly susceptible to mink virus enteritis and feline panleukopenia, with animals developing clinical illness, and several dying within six to ten days of inoculation with lesions typical of parvovirus infection. both viruses were shed in high titre in the feces of infected raccoons, and high antibody titres were stimulated. raccoons ... | 1983 | 6309349 |
| case report on mixed infection of canine parvovirus and canine coronavirus--electron microscopy and recovery of canine coronavirus. | | 1983 | 6314016 |
| aspects of the diagnosis, pathogenesis and epidemiology of canine parvovirus. | between 18 july 1980 and 2 january 1981, 188 samples (145 faeces and 43 intestinal contents) were submitted from dogs with suspected canine parvovirus (cpv) enteritis. cpv was demonstrated in 56 (30%) of these samples; the weekly rate of positive cpv identification was remarkably constant at approximately 30% even though clinical and often post-mortem findings strongly supported a diagnosis of cpv enteritis. the simplest, most sensitive and most rapid method for detection of virus was haemagglut ... | 1983 | 6314962 |
| canine viral enteritis. | canine viral enteritis should be suspected in dogs with an acute onset of vomiting and diarrhea, especially in puppies and where several animals are affected simultaneously. definitive diagnosis requires laboratory confirmation, most often detection of viral particles in the stool. no diagnostic test is entirely specific or absolutely sensitive, however, and laboratory findings should be weighed accordingly. immunization is the key to successful control. effective vaccines for canine parvovirus ... | 1983 | 6316616 |
| comparison of the viral proteins of canine parvovirus-2, mink enteritis virus and feline panleukopenia virus. | canine parvovirus-2 (cpv-2), mink enteritis virus (mev) and feline panleukopenia virus (fpv) were produced using identical cell culture and purification techniques. the distributions of the haemagglutinating activity of the three different parvoviruses in a cscl gradient were similar with haemagglutinating peaks identified at 1.48-1.49, 1.42, 1.36 and 1.30-1.31 g cm-3. the number and distribution of the viral proteins and the equivalent protein molecular weights are similar for all three viruses ... | 1983 | 6316627 |
| systemic and local intestinal antibody response in dogs given both infective and inactivated canine parvovirus. | systemic and local immune responses were evaluated in dogs given infective canine parvovirus (cpv) and 2 administrations of inactivated cpv 6 months later. before the inactivated cpv was given, a jejunal cannulation was performed on the animals. during infective cpv administration, concentrations of class-specific copro- and sero-immunoglobulin (ig)g, iga, and igm were determined by enzyme-linked immunosorbent assay. high concentrations of both copro- and sero-igm, as well as a moderate increase ... | 1983 | 6316818 |
| canine parvovirus immunoprophylaxis: a review. | the presently available data on canine parvovirus is reviewed with particular emphasis on the degree of immunity provided by the various types of vaccines commercially available, the interference of active immunisation by maternally-derived antibody, and the recommendations as to age of vaccination. | 1983 | 6321731 |
| canine parvovirus vaccination efficacy. | | 1984 | 6322410 |
| canine parvovirus vaccination. | | 1984 | 6324448 |
| serologic response of captive coyotes (canis latrans say) to canine parvovirus and accompanying profiles of canine coronavirus titers. | fifty-five of 66 (83%) coyote pups from bitches vaccinated against canine parvovirus (cpv) were seropositive for cpv antibodies at birth. the cpv antibody titer in the pups declined with a half-life of 6.7 days until by the 8th week, only two of 41 (5%) pups were seropositive for cpv antibodies. at 8 wk, 41 of the pups were vaccinated against cpv (killed feline origin vaccine), but only one of 37 (3%) was positive for cpv antibodies at 11 wk. the 8-wk-old pups were either too young to respond to ... | 1984 | 6325726 |
| acute and chronic viral myocarditis. acute diffuse nonsuppurative myocarditis and residual myocardial scarring following infection with canine parvovirus. | | 1984 | 6326581 |
| canine parvovirus vaccination. | | 1984 | 6328735 |
| isolation of canine parvovirus from a dog brain with severe necrotizing vasculitis and encephalomalacia. | | 1984 | 6330014 |
| comparison of hemagglutination and competitive enzyme-linked immunosorbent assay procedures for detecting canine parvovirus in feces. | a competitive enzyme-linked immunosorbent assay (elisa) for detection of canine parvovirus (cpv) antigen in fecal samples was developed. fecal samples were tested by elisa and a direct hemagglutination assay, and the results compared. the tests gave the same results in 83% and 88% of the fecal samples, depending on whether the samples were treated with chloroform. the discrepancies were due to the fact that each test detected virus in certain fecal samples that was not detected by the other. the ... | 1983 | 6337535 |
| a modified live canine parvovirus vaccine. ii. immune response. | the safety and efficacy of an attenuated canine parvovirus (a-cpv) vaccine was evaluated in both experimental and in field dogs. after parenteral vaccination, seronegative dogs developed hemagglutination-inhibition (hi) antibody titers as early as postvaccination (pv) day 2. maximal titers occurred within 1 week. immunity was associated with the persistence of hi antibody titers (titers greater than 80) that endured at least 2 years. immune dogs challenged with virulent cpv did not shed virus in ... | 1983 | 6337780 |
| an electron microscopic study of viruses associated with canine gastroenteritis. | an electron microscopic study was carried out on specimens of feces and intestinal contents from cases of canine gastroenteritis submitted to the diagnostic laboratory, new york state college of veterinary medicine, during 1979-1981. the majority of samples came from new york state and the northeast with no marked shift in distribution over the three year period. canine parvovirus was the major virus identified. in august and september 1980 there was an epidemic of canine gastroenteritis, with 2 ... | 1983 | 6337781 |
| midgut and viral associated proteases of heliothis armigera. | the role played by the gut juice of insects in the infective process of insect viruses was examined. analysis of larval gut extract of heliothis armigera by sds-page revealed protease activity associated with components of molecular weights 48,000 and 94,000. proteases were found to be associated with occlusion bodies and virions of both nuclear polyhedrosis virus (npv) and cytoplasmic polyhedrosis virus (cpv) infecting h. armigera. cpv occlusion bodies were dissolved by gut juice extract at ph ... | 1983 | 6337972 |
| the effects of s-adenosyl methionine (adomet) and its analogues on the control of transcription and translation in vitro of the mrna products of two cytoplasmic polyhedrosis viruses. | s-adenosyl methionine (adomet) and several structurally related compounds were added to in vitro systems for the synthesis of single-stranded rna by cytoplasmic polyhedrosis virus (cpv) types 1 and 2. the effects of these compounds were examined on the level of transcription and methylation of the rna products. of the compounds tested, five increased the polymerase activity in both viruses, the most effective being the d- and l-stereoisomers of s-adenosyl homocysteine (adohcy), and the least eff ... | 1983 | 6359667 |
| chemical synthesis of the 5'-terminal part bearing cap structure of messenger rna of cytoplasmic polyhedrosis virus (cpv): m7g5'pppampg and m7g5'pppampgpu. | the 5'-terminal structures of mrna bearing the so-called 'cap' from cytoplasmic polyhedrosis virus (cpv), m7g5' pppampg and m7g5' pppampgpu, were first chemically synthesized. s,s-di(4-methoxyphenyl) n6-benzoyl-2'-o-methyladenosine 5'-phosphorodithioate ((ars) 2pabmz) was prepared by phosphorylation of the 5'-hydroxyl group of n6-benzoyl-2'-o-methyladenosine with s,s-di(4-methoxyphenyl) phosphorodithioate by tps. by the triester approach using (ars) 2pabmz as starting material, the protected din ... | 1984 | 6369253 |
| specific removal of antibodies with an immunoadsorption system. | a continuous flow immunoadsorption system consisting of a cell separator, protein a-sepharose columns, and a semi-automatic elution component was developed to specifically remove circulating igg. this system provides extensive absorption with an essentially unlimited column bed volume. six dogs were treated a total of 19 times. in no case did fever, sepsis, or respiratory distress result from the treatment. serial blood counts and tests of liver and renal function remained in the normal range. e ... | 1984 | 6369656 |
| characterization of a cytoplasmic polyhedrosis virus infecting manduca sexta. | a cytoplasmic polyhedrosis virus (cpv) infecting manduca sexta was characterized. the genome consisted of ten equimolar rna segments ranging in estimated molecular mass from 0.7 to 3.84 mdaltons and with a total estimated molecular mass of 21.75 mdaltons . the sizes of the individual rna segments provisionally placed this cpv within the type 8 classification of payne and rivers. the polyhedrin protein had an estimated molecular mass of 28 kdaltons . six virion-associated proteins were observed, ... | 1984 | 6373659 |
| comparison of the virus-associated polymerases of cytoplasmic polyhedrosis virus types 1 and 2. | a detailed comparison was made of the virus-associated polymerase activities of cytoplasmic polyhedrosis virus (cpv) types 1 and 2 which had previously been shown to differ in their response to the methyl donor s-adenosyl-l-methionine (adomet). while the type 1 cpv polymerase was approximately twice as active as the type 2 cpv enzyme in the presence of adomet, temperature, ph and divalent cation optima of the two enzymes were similar. both viruses synthesized in vitro single-stranded rna copies ... | 1984 | 6384129 |
| cross-reactivity between cowpox and vaccinia viruses with monoclonal antibodies. brief report. | hybridoma cell lines producing monoclonal antibodies against cowpox virus (cpv) and vaccinia virus (vv) were established to examine the specific and cross-reactive antigenic determinants of these viruses. monoclonal antibodies against cpv (lb red strain) and vv (lister strain and ikeda strain) were classified into several groups on the basis of the results of immunofluorescence and haemagglutination inhibition tests. it was suggested that the groups defined above include the group of antibodies ... | 1984 | 6497657 |
| dog response to plaque variant of canine parvovirus. | | 1983 | 6650021 |
| hemorrhagic enteritis and nonsuppurative myocarditis caused by canine parvovirus. | | 1982 | 6806718 |
| hemagglutination with formalin-fixed erythrocytes for detection of canine parvovirus. | | 1983 | 6824219 |
| canine parvovirus serum neutralizing antibody assay: assessment of factors responsible for disparity of results between tests. | canine parvovirus (cpv) serum neutralization (sn) test components were evaluated to determine their effect on antibody titer results. the use of different strains of cpv and different cell substrates had little effect on assay results. variations in sn antibody titer results were associated with the use of challenge virus preparations that differed in the ratio of hemagglutination units (hau) to infectivity units (faid50). sensitivity and reproducibility can be achieved by using a standardized c ... | 1983 | 6825453 |
| serotherapy for dogs infected with canine parvovirus. | | 1983 | 6865174 |
| [course and reflections on canine parvovirus enteritis in the berlin area]. | | 1983 | 6870469 |
| the present status of canine parvovirosis. | results from studies performed by the authors and by other workers, have greatly increased the knowledge of canine parvovirus. the authors review the situation with particular reference to virology, epidemiology, pathogenesis, pathology and immunoprophylaxis. | 1983 | 6880008 |
| parvovirus enteritis in vaccinated juvenile bush dogs. | parvovirus enteritis developed in 10 of 17 vaccinated juvenile bush dogs (speothos venaticus) from 4 litters in a 5-month period. nine dogs died. the first outbreak involved 6 of 9 bush dogs from 2 litters. each had been vaccinated with a killed feline-origin parvovirus vaccine at 11 and 14 weeks of age. the 6 affected dogs became ill at 29 weeks of age and died. the second outbreak involved a litter of 6 bush dogs. each had been vaccinated every 2 weeks starting at 5 weeks of age. two were isol ... | 1982 | 6890953 |
| canine parvovirus infection. | | 1981 | 6940049 |
| canine parvovirus infection. | | 1980 | 6945518 |
| sequence of terminal regions of cowpox virus dna: arrangement of repeated and unique sequence elements. | one terminal ecori fragment of the genome of cowpox virus (cpv) strain brighton red has been cloned in plasmid pbr325, and the nucleotide sequence of the 2,725-base-pair sal i fragment corresponding to that at the end of the viral genome has been determined. the fragment consists of three unique sequence regions flanking two sets of repeated sequence. the repeated sequence sets are composed of four types of subunits, the majority of which are arranged in higher-order repeat units. the subunits a ... | 1982 | 6961398 |
| titration of a cytoplasmic polyhedrosis virus by a tissue microculture assay: some applications. | a simple tissue microculture technique was developed for the titration of a cytoplasmic polyhedrosis virus (cpv) from euxoa scandens. the procedure was similar to the 50% tissue culture infectious dose assay, but a single infected cell, detected by the presence of cytoplasmic polyhedra, was scored rather than the degeneration of cell monolayers. the filtration of cpv suspensions resulted in decreased virus titers under certain conditions. this microculture assay was used to determine the effect ... | 1980 | 6987194 |
| a single radial haemolysis test for measuring canine parvovirus antibody. | | 1981 | 7015678 |
| production of cytoplasmic polyhedrosis virus (cpv) polyhedra in a gamma irradiated lymantria dispar cell line. | lymantria dispar cells wee exposed to different doses of gamma radiation one hour after infection with cytoplasmic polyhedrosis virus (cpv). it was found that irradiated cells can produce infectious polyhedra. modifications in the structure and in the process of maturation of the polyhedra were noted. the number of polyhedra per cell increased significantly after cell irradiation at 10(4) and 10(5) rads but no change was noted after cell treatment at 10(2) rads. on the other hand, morphological ... | 1981 | 7023418 |
| separation of the plus and minus strands of cytoplasmic polyhedrosis virus and human reovirus double-stranded genome rnas by gel electrophoresis. | the complementary strands of most of the genome double-stranded rna segments of insect cytoplasmic polyhedrosis virus (cpv) and human reovirus are separated for the first time by agarose gel electrophoresis in in the presence of 7 m urea. cpv (+) strands and most reovirus (-) strands migrate faster than the corresponding strands of opposite polarity. glyoxal treatment, which modifies guanine residues and prevents g-c basepairing, results in a loss of strand resolution and concomitantly a signifi ... | 1981 | 7029468 |
| a unique class of compound, guanosine-nucleoside tetraphosphate g(5')pppp(5')n, synthesized during the in vitro transcription of cytoplasmic polyhedrosis virus of bombyx mori. structural determination and mechanism of formation. | two structurally different classes of oligonucleotides accumulate in vitro in cytoplasmic polyhedrosis virus (cpv) transcription mixtures in molar excess as compared to the completed rna products. the first class consists of oligonucleotides which correspond to the 5'-terminal sequence of the virus mrnas (referred to as initiator oligonucleotides). the major species of initiator oligonucleotides are (p)ppapg and (p)ppapgpn together with smaller amounts of homologous capped structures (furuichi, ... | 1982 | 7031064 |
| electrophoretic characterization of proteins and rna of cytoplasmic polyhedrosis virus (cpv) from euxoa scandens. | a cytoplasmic polyhedrosis virus (cpv) was isolated from euxoa scandens and propagated in vitro in lymantria dispar cells. the virions and polyhedra were analyzed by polyacrylamide gel electrophoresis. polyhedra produced in vivo and in vitro contained six polypeptides with identical relative mobilities while nonoccluded viral particles produced in vivo were composed of four polypeptides. the rna content of the purified virions extracted from infected midgut was resolved in ten segments with mole ... | 1981 | 7036955 |
| [3h-methyl]-methionine as possible methyl donor for formation of 5'-terminus of in vitro synthesized mrna of cytoplasmic polyhedrosis virus of silkworm bombyx mori. | the mrna of the cytoplasmic polyhedrosis virus of silkworm bombyx mori could be synthesized in vitro through the action of the virion associated rna-polymerase in the presence of [3h-methyl]-methionine instead of s-adenosyl-l-methionine. the 3h-mrna is isolated from the reaction mixture through a column of deae-sephadex a-25 and digested with nuclease p1 and snake venom phosphodiesterase. the results of paper electrophoresis show that the methyl group of methionine is incorporated into the 5'-te ... | 1981 | 7038870 |
| development of a vaccine incorporating killed virus of canine origin for the prevention of canine parvovirus infection. | a parvovirus of canine origin, cultured in a feline kidney cell line, was inactivated with formalin. three pilot serials were produced and three forms of finished vaccine (nonadjuvanted, single adjuvanted and double adjuvanted) were tested in vaccination and challenge trials. a comparison was also made with two inactivated feline panleukopenia virus vaccines, one of which has official approval for use in dogs. the inactivated canine vaccine in nonadjuvanted, adjuvanted or double adjuvanted form ... | 1982 | 7039811 |
| isolation of genome-enzyme complex from cytoplasmic polyhedrosis virus of silkworm bombyx mori. | the genome-enzyme complex is isolated from the silkworm cytoplasmic polyhedrosis virus with deae-sephadex column chromatography after ultraviolet irradiation. the genome-enzyme complex shows both rna-polymerase and methyltransferase activities while using 3h-utp and [3h-methyl]-s-adenosyle-l-methionine as substrates. like the double-stranded rna genome of cpv, the genome-enzyme complex could be separated into nine segments on polyacrylamide gel electrophoresis. it is demonstrated that the rna po ... | 1982 | 7048527 |
| maternally derived immunity to canine parvovirus infection: transfer, decline, and interference with vaccination. | antibody to canine parvovirus (cpv) was transferred from an immune bitch to her pups through the placenta and colostrum. colostral transfer accounted for approximately 90% of the maternally-derived cpv antibody. after suckling, pups and hemagglutination-inhibition titers that averaged 50% of their dam's titer. maternally derived cpv antibody declined with a half-life of 9.7 days. pups with hemagglutination-inhibition titers greater than or equal to 1:80 were immune to oronasal challenge with vir ... | 1982 | 7056660 |
| radiographic appearance of canine parvovirus enteritis. | sixty dogs with serologically proved parvovirus infection were radiographically evaluated for signs of gastrointestinal disease. patient grouping was based on duration of illness, which correlated generally with severity of clinical signs. early in the disease, the radiographic appearance usually was normal. as the disease progressed, abnormal gas and fluid distention of the small bowel became evident. contrast radiographic findings usually were normal early in the disease but became abnormal as ... | 1982 | 7056662 |
| canine parvovirus infection potentiates canine distemper encephalitis attributable to modified live-virus vaccine. | twelve gnotobiotic dogs from 2 litters were allotted to 3 groups. group a dogs received a modified-live polyvalent (canine distemper, adenovirus type 2, and parainfluenza virus and leptospira -canicola-icterohemorrhagiae bacterin) vaccine 3 days prior to oral inoculation with canine parvovirus (cpv). group b dogs received cpv alone. group c dogs received 1 dose of vaccine only. in none of the 9 cpv-inoculated dogs did clinical signs of cpv infection develop, although high serum antibody titers f ... | 1982 | 7061309 |
| experimental infection of conventional dogs with canine parvovirus. | four 6-week-old conventional pups were inoculated with a parvovirus (pv) isolated from the feces of a dog with naturally occurring enteritis. blood for hematologic studies, virus isolation (vi), and antibody titration and feces for vi and negative-contrast electron microscopy were collected on day 0 and daily until necropsy. beginning at postinoculation day 2, necropsies were done and specimens were collected for immunofluorescence, vi, and light microscopic examination. the pv infection was con ... | 1982 | 7073093 |
| vaccination against canine parvovirus disease. | | 1982 | 7080409 |
| vaccination against canine parvovirus disease. | | 1982 | 7080428 |
| electron microscopic findings on epithelial cells of lieberkühn's crypts in canine parvovirus infection. | | 1982 | 7098243 |
| canine parvovirus infection in housed raccoon dogs and foxes in finland. | an outbreaks of severe enteritis occurred among young raccoon dogs on fur farms in eastern finland. post mortem examinations revealed gross and microscopic lesions which were typical of parvovirus infections described in cats, mink and dogs. the intestine was dilatated, oedematous and the normal villi were significantly reduced. a parvovirus was isolated from faeces and found to resemble canine parvovirus by its ability to haemagglutinate pig erythrocytes at ph 7.2 and its antigenic properties. ... | 1982 | 7101696 |
| generalized parvovirus disease in neonatal pups. | generalized canine parvovirus disease was diagnosed in a litter of pups that died when 3 to 9 days old. parvovirus was isolated from the heart, lungs, liver, kidneys, and small intestine. histologically, lesions were characterized by hemorrhage and necrosis in the brain, liver, lungs, kidneys, lymphoid tissues, and gastrointestinal mucosa. intranuclear inclusions were found in vascular endothelium, heart, lungs, liver, kidneys, adrenal cortex, and gastrointestinal tract. | 1982 | 7107487 |
| canine parvovirus infection in australia during 1980. | a questionnaire sent to all veterinary practitioners in australia and many in new zealand asking for details of their experience with canine parvovirus infections in 1980 elicited the following information. in 1980 explosive outbreaks of disease occurred in most parts of australia. there was no obvious pattern of spread over the continent as a whole. in many cases outbreaks in country areas occurred after dog shows. canine parvovirus enteritis affected all age groups with an overall mortality of ... | 1982 | 7112869 |
| canine parvovirus: a biochemical and ultrastructural characterization. | a canine virus derived from a diseased dog has been plaque-purified and characterized in detail. analysis of infected cells demonstrated that virus antigen accumulated in the nucleus at 12 to 24 h post-infection and the cytopathology at the ultrastructural level was diagnostic of a parvovirus infection. the purified virus particles were 23 to 26 nm in diam. and banded at a density 1.44 g/ml in cscl. detailed biochemical analysis revealed a single-stranded dna genome and three structural proteins ... | 1982 | 7130947 |
| sero-epidemiologic survey on canine parvovirus infection. | | 1982 | 7132022 |
| development of a modified live, canine origin parvovirus vaccine. | a modified live, canine origin parvovirus vaccine was tested for safety, efficacy, and clinical performance. the vaccine protected dogs from challenge of immunity with canine parvovirus (cpv) that caused clinical illness in all nonvaccinated dogs. vaccinates all developed cpv serum neutralization antibody titers, with a mean value of 1,664. challenge virus was not isolated from vaccinates, but feces from nonvaccinated dogs were cpv-positive for up to 4 days following challenge. in a pathogenicit ... | 1982 | 7141990 |
| epizootic of viral enteritis in dogs in thailand. | an epizootic of enteritis occurred in dogs in thailand during 1979. observations were made on 44 dogs that had clinical signs of enteritis or had a recent history compatible with a clinical diagnosis of enteritis. eight of the 44 dogs died. gross and histopathologic examinations performed on these dogs revealed that the lesions were similar to those described for canine viral enteritis. antigens that agglutinated rhesus macaque rbc were detected in feces from 4 of 20 dogs. cytopathic effects wer ... | 1982 | 7149420 |
| comparison of systemic and local immunity in dogs with canine parvovirus gastroenteritis. | to determine whether resistance to canine parvovirus (cpv) gastroenteritis is mediated by local or systemic immunity or both, an enzyme-linked immunospecific antibody assay (elisa) was developed that quantitated different classes of antibody to cpv. antibody levels in serum and feces of dogs with cpv-associated gastroenteritis were compared with their clinical signs and viral hemagglutination (ha) titers. dogs with high levels of cpv coproantibody had a favorable clinical prognosis, high serum a ... | 1982 | 7152659 |
| maternal antibody, vaccination and reproductive failure in dogs with parvovirus infection. | the maternal antibody (mab) titre to canine parvovirus (cpv) was determined on consecutive serums from 39 puppies in 7 litters. vaccination with inactivated cpv was performed at a variety of ages and the response of the puppies determined. transfer of mab was demonstrated in 71% (5/7) of the litters and persisted for up to 10 weeks in some litters. mab titres of greater than 20 precluded a vaccination response by puppies. sixty- one per cent (8/13) of puppies responded to vaccination when the ma ... | 1982 | 7168717 |
| [identification of canine parvovirus infections in madagascar]. | | 1982 | 7170360 |
| canine parvovirus infections in a colony of dogs. | a serological study of canine parvovirus (cpv) infections in a colony of dogs was conducted over a period of 8 months. twenty-two of 24 adults samples initially had significant antibody titres to cpv. nine litters of puppies were bled at fortnightly intervals and the sera tested for antibodies to cpv. twenty-nine of 35 naturally pv infections observed were subclinical. a puppy in one litter developed vomiting and diarrhoea during the same period as seroconversion to cpv. four puppies from a furt ... | 1982 | 7179717 |
| prevalence and conversion of canine parvovirus antibody in various dog colonies in japan. | | 1982 | 7182643 |
| canine parvovirus infection. | | 1980 | 7210433 |
| studies on canine parvovirus infections: development of an inactivated vaccine. | parvoviruses isolated from the intestines of dogs that died of an enteric infection were propagated in various parasynchronized canine and feline cell cultures. viral antigen could be visualized in infected cell cultures with the aid of fluorescein-labeled feline, as well as porcine, parvovirus antisera, and in an indirect test with sera from dogs that had recovered from a parvovirus infection. the virus hemagglutinated porcine rbc at 4 c and 25 c but not at 37 c. an inactivated canine parvovir ... | 1980 | 7212436 |
| acute and chronic canine parvovirus myocarditis following intrauterine inoculation. | canine myocarditis virus was inoculated into puppies in utero 8 days before parturition. puppies were clinically normal at birth. one puppy died 23 days after inoculation and a second puppy was comatose before euthanasia on day 27 post inoculation. both had acute, non-suppurative myocarditis, and parvovirus was isolated from the heart of each pup. two other puppies remained clinically normal until euthanasia at 87 and 131 days after inoculation. these latter puppies had extensive, focal fibrosis ... | 1980 | 7225002 |
| canine parvovirus disease: a caution against routine vaccination. | | 1980 | 7225013 |
| canine parvovirus in a commercial kennel: epidemiologic and pathologic findings. | a study was conducted at a large canine commercial kennel that had suffered serious losses due to epidemic diarrheal disease following the introduction of canine parvovirus (cpv) into the kennel population. mortality was highest in weaned (9- to 12-week-old) puppies coincident with the decline in maternal antibody titers. virus was present in fecal samples from both fatal and non-fatal cases. intestinal lesions of varying severity were present in dogs that died. one case of myocarditis occurred ... | 1981 | 7226850 |
| canine parvovirus: a cause of chronic myocardial fibrosis and adolescent congestive heart failure. | | 1980 | 7230747 |
| vaccination against canine parvovirus. | | 1981 | 7236147 |
| canine parvovirus disease. | | 1980 | 7257105 |
| stimulation of transcription by s-adenosyl-l-homocysteine and virion-encapsidated methyl donor in spring viraemia of carp virus. | s-adenosyl-l-methionine (sam), a methyl donor, and its analogue s-adenyl-l-homocysteine (sah), an inhibitor of methylation, stimulate the activity of spring viraemia of carp virus (svcv) virion transcriptase. the stimulation observed for svcv is analogous to that observed previously (furuichi, 1974, 1978) for a totally unrelated virus, cytoplasmic polyhedrosis virus (cpv). in the absence of exogenous sam, rna with 5'-methylated termini (presumptive gpppampap) was produced, indicating that svcv h ... | 1981 | 7276915 |
| canine parvovirus myocarditis: clinical signs and pathological lesions encountered in natural cases. | canine parvovirus (cpv) myocarditis was diagnosed in 11 puppies during 1979. the diagnosis was made at histopathological examination on the basis of 2 characteristic lesions: a subacute to chronic fibrous myocarditis and the presence of large, basophilic intranuclear inclusions in the cardiac myofibres. the puppies varied from 31/2 to 8 weeks of age and all died suddenly without prior symptoms except for 1 pup which developed a severe respiratory dyspnoea 12 h before death. the presence of white ... | 1981 | 7277370 |
| [canine parvovirus infection in a group of beagles (author's transl)]. | an outbreak of canine parvovirus infection in a group of 26 beagles was described. the disease characterized by acute intestinal involvement was highly contagious but fatality was low (1/26). transient leukopenia was recorded in some animals. all the convalescent sera were positive in agar gel diffusion test using feline panleukopenia virus antigen. histopathological examination on fetal dog revealed regressive change associated with formation of amphophilic intranuclear inclusion bodies in the ... | 1981 | 7286068 |
| canine parvovirus infection. | | 1981 | 7287196 |
| studies on canine parvovirus isolation, experimental infection and serologic survey. | | 1981 | 7289337 |
| a modified live canine parvovirus strain with novel plaque characteristics. i. viral attenuation and dog response. | a canine parvovirus (cpv) strain (c-780916) was found attenuated for pups at 80, but not after 51 serial passages in dog kidney cell (dkc) cultures. a variant viral population ('large plaque') emerged after prolonged cultivation in dkc cultures that may be associated with reduced native virulence. dogs vaccinated with modified cpv developed high hemagglutination-inhibiting (hi) antibody titers within 4 days of incoluation and antibody persisted. vaccinated animals shed small amounts of virus in ... | 1981 | 7318443 |