| internal mammary artery use. sternal revascularization and experimental infection patterns. | we have described previously the acute sternal devascularization produced by mobilization of one or both internal mammary arteries (imas). the present experiments were conducted to examine the time course of sternal revascularization and infection patterns after ima use. twenty-four 8-week-old domestic pigs were obtained from a herd in which active streptococcus faecalis had been detected in recent litters. after control blood flow procedures (microspheres) were completed, each pig underwent a m ... | 1991 | 1934421 |
| in situ localization of transforming growth factor beta 1 in porcine heart: enhanced expression after chronic coronary artery constriction. | we investigated the expression of transforming growth factor beta 1 (tgf-beta 1), a polypeptide differentiation factor probably associated with angiogenic properties in chronically hypoperfused heart tissue. a slowly swelling ameroid constrictor was implanted around the coronary circumflex artery (cx) of young domestic pigs. two to three weeks after, significant cx stenosis of more than 90% and coronary collateralization could be demonstrated angiographically. the cx dependent experimental myoca ... | 1991 | 1942095 |
| [stomach emptying after stomach resection with and without retention of duodenal passage]. | on domestic pigs 2/3 gastrectomies with retention and elimination of the duodenal passage were carried out. postprandial gastric emptying was measured scintigraphically for 4 h and compared with a control group (laparotomy only). for the semi-solid, 99mtc-labeled test meal delayed gastric emptying after elimination of the duodenal passage by roux reconstruction could not be shown. there was no difference in gastric emptying between b-i and roux-en-y partial gastrectomy. also alteration of the le ... | 1991 | 1943409 |
| epidemiologic study and control of taenia solium infections with praziquantel in a rural village of mexico. | this study reports the results of an epidemiologic survey for the detection of taenia solium in a rural village of 559 inhabitants in sinaloa, mexico, as well as a large scale treatment of the population with praziquantel. the study was carried out in two stages. in stage 1, serial stool analysis of 392 persons detected a cluster of three t. solium tapeworms. a fourth t. solium tapeworm was detected through a household census, giving a 1.32% prevalence rate for this helminth. over 70% of the pop ... | 1991 | 1951862 |
| ischemic preconditioning preserves creatine phosphate and intracellular ph. | ischemic preconditioning slows atp depletion and ultrastructural damage during the final episode of ischemia. to define the influence of creatine phosphate (cp) and intracellular ph (phi) on this effect, cp and phi were serially measured in porcine hearts without collateral circulation by using 31p-nmr spectroscopy and ultrastructural examination. | 1991 | 1959199 |
| the role of alpha 1-adrenoceptors in adrenaline-induced hyperkalaemia. | the hyperkalaemic action of adrenaline was investigated in 44 anaesthetized domestic pigs. plasma and epicardial concentrations of k+ were measured, in the latter case with an ion-selective electrode. adrenaline 10 micrograms kg-1 caused a rapid increase in the plasma concentration of k+ from 4.2 to 5.9 mmol litre-1. the magnitude and the time course of epicardial concentration of k+ were similar. alpha-adrenoceptor block with either phentolamine 5 mg kg-1 (non-selective block) or prazosin 0.1 m ... | 1990 | 1979911 |
| protective effects of nipradilol, isosorbide dinitrate, and bunazosin on coronary artery constriction induced by intracoronary injection of acetylcholine in pigs. | protective effects of nipradilol, a newly synthesised vasodilating beta adrenoceptor antagonist, isosorbide dinitrate, and bunazosin on coronary artery constriction induced by intracoronary injection of acetylcholine were determined by coronary arteriography and compared in vivo in pigs. | 1990 | 1982930 |
| enhancement of re-epithelialization with topical zinc oxide in porcine partial-thickness wounds. | we investigated the effect of locally applied zinc on the healing of partial-thickness skin wounds in the domestic pig using two zinc compounds (zinc oxide and zinc sulfate) in two different vehicles (a gauze compress and a collagen sponge). the rate of re-epithelialization was determined morphometrically 48 and 64 hr after infliction of standardized square wounds (4.8 cm2 and 400-microns deep) with an electrokeratome. zinc oxide in gauze significantly (p less than 0.05) increased re-epitheliali ... | 1991 | 1990212 |
| growth of lung allografts after experimental transplantation. | heart and lung transplantation has been performed in cases of end-stage cardiopulmonary disease in infants. nevertheless, it still remains unclear whether lung allografts adjust to a growing organism. in 6 young domestic pigs unilateral left lung allotransplantation was performed. immunosuppression consisted of a triple drug therapy including cyclosporine, azathioprine, and corticosteroids. lung growth was studied by using bronchography, pulmonary angiography, and lung histology. after 11 weeks ... | 1991 | 2011847 |
| the transition from maternal to zygotic control of development occurs during the 4-cell stage in the domestic pig, sus scrofa: quantitative and qualitative aspects of protein synthesis. | a study was conducted to identify the embryonic stage when the zygotic genome begins to direct development and to characterize protein synthesis in pig oocytes and embryos. reproductive tracts of gilts were flushed to obtain unfertilized oocytes (ufo), zygotes (z), 2-, 4-, and 8-cell embryos, compact morulae (m), initial blastocysts (ib), blastocysts (b), and hatched blastocysts (hb). pig eggs and embryos were cultured in medium containing 1 microm l-[35s]methionine and evaluated for amino acid ... | 1991 | 2015352 |
| no eeg evidence of acute tolerance to desflurane in swine. | desflurane is a potent inhaled anesthetic associated with a dose-dependent depression of cortical electrical activity. recently, it has been suggested that the burst suppression pattern seen in dogs given moderately high doses (2.0 mac) of desflurane may spontaneously subside. this observation suggests the development of acute tolerance to at least some of the anesthetic effects of this drug. no other volatile anesthetic has been found to produce acute tolerance. we attempted to replicate these ... | 1991 | 2021206 |
| lung growth after experimental pulmonary transplantation. | replacement of the heart and both lungs or single lung transplantation has been performed in a few cases of terminal (cardio) pulmonary disease in childhood. it remains unclear whether pulmonary allografts will meet the demands of a growing organism. six domestic pigs (mean body weight, 24 kg) underwent left lung transplantation from donors of equal weight. immunosuppression consisted of cyclosporine, azathioprine, and corticosteroids. after the pigs doubled their body weight, growth of the lung ... | 1991 | 2031927 |
| origin of anterior interventricular vein blood in domestic swine. | this study tested the hypothesis that anterior interventricular vein effluent of domestic swine is composed primarily of blood draining the perfusion territory of the left anterior descending coronary artery. as a corollary, the extent to which circumflex and right coronary inflow contributes to anterior interventricular vein outflow also was determined. experiments were conducted in vitro with buffer-perfused swine hearts in which anterior interventricular vein flow was measured under various c ... | 1991 | 2035692 |
| [masticatory muscles of domestic sheep and swine in ontogenesis]. | age changes of morphometrical parameters of the masticatory muscles have been analyzed in domestic sheep and pigs of white large breed in the following age groups: 2-, 3-, 4-month-old fetuses, newborns, 4-month-old lambs, 10-month-old pigs, 18-month-old lambs, mature she-sheep and brood-sows. uneven weight growth of the masticatory muscles in the sheep and pigs during the prenatal ontogenesis should be considered as a consequence of recapitulation of their phylogenesis, and in the postnatal onto ... | 1991 | 2053870 |
| contribution of the gastrointestinal tract to lorazepam conjugation and clonazepam nitroreduction. | domestic pigs received single intravenous and oral doses of lorazepam or clonazepam (1 mg/kg), benzodiazepine derivatives biotransformed by glucuronide conjugation and nitroreduction, respectively. blood samples were simultaneously drawn from portal venous and systemic venous sampling sites during 8 h after dosage. after intravenous dosage with either drug, the area under the serum concentration curve (auc) for the intact drug, as well as for the principal metabolites (lorazepam glucuronide and ... | 1991 | 2057519 |
| persistent reversal of diabetes by transplantation of fetal pig proislets into nude mice. | facing the limited availability of human adult and fetal pancreases, fetal pig proislets (pancreatic islet precursors) were investigated in view of several inherent advantages. six litters of fetuses of mean +/- se gestational age 75 +/- 3 days were obtained from commercially available farm pigs. pancreatic tissue was gently digested with collagenase, then a 10-day culture was performed. during culture, fetal proislets showed no insulin response to glucose alone but a significant response to glu ... | 1991 | 2060721 |
| cardiac resuscitation by extracorporeal circulation after failure of conventional cpr. | after cardiac arrest, return of cardiac function and effective circulation are contingent on prompt restoration of myocardial blood flow. because conventional closed-chest cpr has limited hemodynamic efficiency, we investigated venoarterial ecc utilizing peripheral vascular access as an alternative for cardiac resuscitation. ventricular fibrillation was induced in domestic pigs by alternating current delivered to the endocardium of the right ventricle. conventional closed-chest cpr was begun aft ... | 1991 | 2066645 |
| [histotopographic studies of the intramural coronary arteries in the trabecula septomarginalis of the right cardiac ventricle in swine (sus scrofa domesticus) and dwarf goats (capra aegagrus f. domestica)]. | in the trabecula septomarginalis (moderator band) of pig and pygmy goat regularly till to 6 arteries are found, which traverse from the interventricular septum to the m. papillarius magnus. these intramural coronary arteries (diameter 50-300 microns)--without any exception-musculoelastic intimal thickenings are recognizable, which often marked extensive and formed in the whole vessel length. it is concluded that coronary arteries enlarge in response to increasing intimal thickening and that such ... | 1990 | 2077762 |
| morphology of normal and osteochondrotic porcine articular-epiphyseal cartilage. a study in the domestic pig and minipig of wild hog ancestry. | osteochondrosis is a generalized skeletal disorder that affects the growth cartilage in the growing domestic pig but not in the minipig of wild hog ancestry. in the present study, we compare the ultrastructure of the articular and epiphyseal growth cartilage in the domestic pig with that in the minipig. the domestic pigs had areas of enlarged epiphyseal cartilage with chondronecrosis, which had caused focal impairment of the endochondral ossification, with retention of cartilage in the subchondr ... | 1990 | 2077805 |
| recovery after cold cardioplegic arrest of isolated blood-perfused hearts excised from non-anesthetized pigs. | an isolated blood-perfused pig heart model has been established in order to evaluate the recovery of hearts obtained from slaughterhouse domestic pigs avoiding anesthesia and direct experiments on animals. eleven hearts subjected to 9 min of normothermic ischemia were infused with cold modified bretschneider solution. after 180 min of cardioplegic-induced global ischemia (including 9 min of normothermic ischemia) 8 hearts were reperfused for 120 min. left ventricular function (measured isovolume ... | 1990 | 2079092 |
| brain oedema and intracranial pressure in superior sagittal sinus balloon occlusion. an experimental study in pigs. | about 2/3 of all patients with thrombosis of the superior sagittal sinus (sss) develop signs of increased icp and/or brain oedema (be). the time of onset and the spectrum of symptoms in sss thrombosis vary extremely. this variability might be caused by differences in pathomechanism like be and rise of icp, parameters studied in the present contribution. 10 domestic pigs received a standardized occlusion of the sss with two different balloon types (spherical and cylindrical). they were monitored ... | 1990 | 2089903 |
| [animal experiments for testing the behavior of compacted bone sections using compression osteosynthesis after hyperthermic denaturation]. | in animal experiments on domestic pigs the behaviour of hyperthermically denatured autogenic compact bone grafts after orthotopic replantation was investigated histologically. it was shown that the inductive osteogenetic celldifferentiation of the lair tissue caused by the autogenetic osteoimplantation depends on the location relationship of the replanted bone grafts to the lair bone tissue. this differentiation had progressed after 14 and 21 days further in the upper indifference area than in t ... | 1990 | 2095646 |
| coronary reactivity in the porcine heart after short lasting myocardial ischaemia: effects of duration of ischaemia and myocardial stunning. | the aim was to characterise reactive hyperaemia and endothelium dependent (adp) and independent (adenosine) vasodilatation after ischaemic periods of increasing duration, and in the stunned myocardium. | 1990 | 2097067 |
| intravenous midazolam suppression of pentylenetetrazol-induced epileptogenic activity in a porcine model. | generalized tonic-clonic seizures are a neurologic emergency. duration of ictal activity has been associated with neurologic sequelae. the purpose of this study was to determine if midazolam, a short-acting benzodiazepine, could effectively ablate ictal activity in an animal model without significant cardiorespiratory compromise. ten domestic swine (10 to 20 kg) were ventilated and hemodynamically monitored. bifrontal craniotomies were performed and electrocortical activity was recorded througho ... | 1990 | 2105874 |
| increases in coronary vein co2 during cardiac resuscitation. | we investigated the aortic, mixed venous, and great cardiac vein acid-base changes in eight domestic pigs during cardiac arrest produced by ventricular fibrillation and during cardiopulmonary resuscitation (cpr). the great cardiac vein pco2 increased from a control value of 52 +/- 2 to 132 +/- 28 (sd) torr during cpr, whereas the arterial pco2 was unchanged (39 +/- 4 vs. 38 +/- 4). the coronary venoarterial pco2 gradient, therefore, increased remarkably from 13 +/- 2 to 94 +/- 29 torr. the simul ... | 1990 | 2112125 |
| [determinants of survival in cardiopulmonary resuscitation]. | prognostic indices for survival after cardiopulmonary resuscitation (cpr) were investigated in 14 male sprague-dawley rats (500 +/- 50 g) and in 16 domestic pigs (25 +/- 4 kg). arterial and venous blood gas and lactate measurements in association with the coronary perfusion pressure (cpp) and the end-expiratory co2 concentration (etco2) were evaluated. additional parameters in the porcine studies were coronary venous blood gas measurements and intramyocardial ph. volume controlled ventilation wa ... | 1990 | 2112683 |
| opioid control of growth hormone in the suckled sow is primarily mediated through growth hormone releasing factor. | endogenous opioid peptides mediate the effect of suckling on lh and prl in the domestic pig. however, the role of opioids in modulating gh during lactation in swine is not known. primiparous sows that had been immunized against grf(1-29) conjugated to human serum albumin (grf-hsa, n = 5) or hsa (n = 4) were used to determine changes in gh after naloxone. treatments were imposed in all sows on day 21 of lactation when antibody titers were 9100 +/- 1629. all sows received (i.v.) naloxone (0.25 mg/ ... | 1990 | 2114957 |
| mono-hydroxyeicosatetraenoic acids during porcine endotoxemia. effect of a platelet-activating factor receptor antagonist. | infusion of endotoxin into domestic pigs induces an acute respiratory failure that has many similarities with the adult respiratory distress syndrome. we hypothesized that mono-hydroxyeicosatetraenoic acids (hete) and platelet-activating factor (paf) might be involved in this model of respiratory failure. escherichia coli endotoxin (055-b5) was infused intravenously into anesthetized young pigs at 5 micrograms/kg the first hour, followed by 2 micrograms/kg/hour for 3 hours in the presence and ab ... | 1990 | 2116563 |
| assignment of nucleoside phosphorylase gene to q2.1----q2.2 region of chromosome 7 in the pig, sus scrofa domestica l. | using in situ hybridization with a human probe, we have mapped the nucleoside phosphorylase gene on pig chromosome 7. these results are in agreement with those obtained by other groups, but give a more precise localization in the q2.1----q2.2 region of chromosome 7. | 1990 | 2117408 |
| occlusive dressings. does dressing type influence the growth of common bacterial pathogens? | we studied the effect of different occlusive dressings and of air exposure on the growth of four pathogenic bacteria in wounds. partial-thickness wounds on domestic pigs were inoculated with staphylococcus aureus, clostridium perfringens, bacteroides fragilis, or pseudomonas aeruginosa. each wound was covered with three dressings (duoderm, opsite, or vigilon), or left exposed to air. groups of wounds were sampled at 24, 48, and 72 hours. staphylococcus aureus reached high levels beneath all of t ... | 1990 | 2119166 |
| in vivo evaluation of simultaneous administration of incompatible drugs via a double-lumen peripheral catheter. | for the critically ill patient with complex and prolonged needs, multiple drug infusions and, when indicated, peripheral hyperalimentation require simultaneous administration through a simple peripheral catheter site with a multilumen catheter. we studied a double-lumen peripheral venous catheter. ten domestic swine, 10 to 20 kg, were divided into two groups of five each. total parenteral nutrition was administered through the distal port and phenytoin was administered as a bolus and as an infus ... | 1990 | 2119936 |
| brief report: experimental hepatitis e infection in domestic pigs. | | 1990 | 2122999 |
| the high resolution r-banded karyotype of sus scrofa domestica l. | | 1990 | 2133260 |
| localization of atrial natriuretic peptide/cardiodilatin (anp/cdd)-immunoreactivity in the lacrimal gland of the domestic pig. | the presence of atrial natriuretic peptic/cardiodilatin-immunoreactive material was demonstrated in the lacrimal gland of the domestic pig by high performance liquid chromatography and radioimmunoassay. the immunohistochemical localization revealed a distinct population of cuboid or spindle-shaped anp/cdd-ir cells in the epithelium of the terminal portion of the secretory tubules. in addition, a moderate number of positive cells was localized intraepithelially in the intralobular ducts as well a ... | 1990 | 2138565 |
| [immunogenetic characteristics of the gene fund of kakhetian swine and dynamics of population parameters in several generations]. | some peculiarities of gene fund and dynamics of populational characters of the oldest in europe kakhetian (georgian) pigs were investigated during 18 years (10 generations). genetic peculiarity of the aboriginal species populations in conditions of intensive pressure of natural selection and relatively weak artificial selection was determined with the help of codominant alleles of the blood groups e system. considerable qualitative and quantitative differences were detected between kakhetian pig ... | 1990 | 2146185 |
| simulated left ventricular aneurysm and aneurysm repair in swine. | patch reconstruction of left ventricular aneurysm may be superior to linear closure, but this hypothesis has not been tested experimentally. accordingly, six anesthetized domestic pigs were instrumented to measure regional left ventricular wall thickening, stroke volume, systolic left ventricular pressure, and myocardial oxygen consumption. with total bypass and cardioplegia, a 6 by 8 cm dacron patch was inserted into the anteroapical left ventricle. simulations were as follows: left ventricular ... | 1990 | 2146447 |
| restenosis after balloon angioplasty. a practical proliferative model in porcine coronary arteries. | a model of proliferative human restenosis was developed in domestic pigs by using deep injury to the coronary arterial media. metal wire coils were delivered percutaneously to the coronary arteries of 11 pigs with an oversized, high-pressure (14 atm) balloon and were left in place for times ranging from 28 to 70 days. during placement, the balloon expanded the coils and delivered them securely within the arterial lumen. light microscopic examination of the vessels confirmed fracture of the inter ... | 1990 | 2146991 |
| detection of aujeszky's disease virus in nasal cells of fattening pigs by immunoassay. | both conventional and specific pathogen free pigs were inoculated intranasally with a strain of aujeszky's disease virus (adv). nasal cells were collected daily by swab, aspiration or wash. the nasal cells were examined for adv by isolation on cell culture, direct or indirect immunofluorescence and immunoperoxidase staining by monoclonal antibodies. the infected pigs were studied for nasal shedding of infected cells until 30 days after infection. the study was also extended to naturally infected ... | 1990 | 2154020 |
| fasting energy metabolism of the yucatan miniature pig. | the fasting metabolic rates (fmr) of yucatan miniature swine were determined using an open-circuit indirect respiration calorimeter. mature nulliparous females had a mean fmr of 93 kcal/kg bw.75 and did not change significantly during the estrous cycle. this value is comparable to that observed in mature domestic swine. the calculated metabolizable energy requirement for maintenance for the yucatan sow is 116 kcal/kg bw.75. growing yucatan boars had fmr of 127, 119 and 101 kcal/kg bw.75 at 15, 2 ... | 1990 | 2157095 |
| normal physiological values for conscious pigs used in biomedical research. | although the domestic pig is rapidly becoming an animal of choice in certain areas of biomedical research requiring a large animal model, effective utilization of the species is often encumbered by a lack of reference values for common functional variables. to address this problem, normal data for over 100 physiologic or related variables were collected from conscious chronically instrumented animals that were maintained under near basal conditions. included were measurements of body composition ... | 1990 | 2162986 |
| serologic survey for transmissible gastroenteritis virus neutralizing antibodies in selected feral and domestic swine sera in the southern united states. | serum samples collected from feral and domestic swine (sus scrofa) in florida and feral swine in georgia and texas were assayed by plaque reduction for their virus neutralizing (vn) antibodies against the porcine transmissible gastroenteritis virus (tge). none of 560 samples collected from feral swine contained vn antibodies for tge virus, but experimentally infected feral swine seroconverted. none of 665 samples from domestic swine contained tge-vn antibodies. these results indicate feral swine ... | 1990 | 2167395 |
| neuromuscular transmission in the gastrocnemius muscle of young domestic and wild pigs. | the gastrocnemius muscle was stimulated in situ in young female domestic pigs (dp, sus scrofa domestica, german landrace; n = 24) and in european wild pigs (wp, sus scrofa scrofa; n = 20), by short (0.1 ms) square-wave impulses via the sciatic nerve. evoked compound action potentials were recorded from the sciatic nerve, from the ramus muscularis distalis of the tibial nerve and from the end plate region of the muscle tissue. maximum nerve conduction velocities (ncv) were 58.8 +/- 10.4 m/s in dp ... | 1990 | 2168115 |
| c-band fusion and behaviour of the involved chromosomes during meiotic prophase i of the male domestic pig. | behaviour of acrocentric chromosome synaptonemal complexes (scs) and constitutive heterochromatin (c-band) during meiotic prophase i of the male domestic pig was studied using surface spreading and silver staining techniques. at late zygotene c-band regions of complete or incomplete scs of the acrocentric chromosomes are represented by enlarged structures. at the same time these structures commenced fusion, which is accomplished at pachytene. using kinetochores and nors as markers, the pachytene ... | 1990 | 2211180 |
| recruitment of mononuclear cells by endothelial cell binding into wounded skin is a selective, time-dependent process with defined molecular interactions. | wound healing involves a complex series of interactions between cells in the dermis and epidermis, and important relationships exist between keratinocytes and resident dermal cells. monocytes and lymphocytes secrete cytokines that are capable of stimulating dermal repair and influencing keratinocyte and fibroblast migration and proliferation, although the mechanism by which mononuclear cells are recruited into the wound is unknown. we have tested the hypothesis that in wounded skin specialized e ... | 1990 | 2212726 |
| maintenance and differentiation in culture of pluripotential embryonic cell lines from pig blastocysts. | cell lines were established from explanted blastocysts of domestic pigs; the cells could be maintained indefinitely when grown on mouse fibroblast feeder cell layers. they differentiate spontaneously at high densities, or when allowed to form aggregates when cultured on a non-adhesive substratum. their appearance and differentiative behaviour resembles that of mouse embryonic stem cell lines. we are currently attempting to establish whether these cultures represent primary ectodermal lineages wh ... | 1990 | 2213715 |
| responses of harbor seal and pig heart to progressive and acute hypoxia. | myocardial oxidative and glycolytic reserves were evaluated in four harbor seals, phoca vitulina richardsi, and six domestic pigs, sus scrofa (hematocrits: 58 +/- 5 and 34 +/- 1%., respectively). progressive hypoxia was induced by lowering arterial hemoglobin-oxygen saturation in 10% decrements, each maintained for 10-min periods, until the onset of heart failure. myocardial oxygen consumption rate (vo2), lactate release/uptake rate (l), and triple product, an index of myocardial energetic deman ... | 1990 | 2221153 |
| nisoldipine inhibits lipid peroxidation induced by coronary occlusion in pig myocardium. | the aim was to investigate the effect of the ca++ channel blocker nisoldipine on the content of lipid peroxidation products in pig myocardium after acute coronary occlusion. | 1990 | 2224937 |
| protective effect of verapamil in ischemic porcine hearts: analysis of ultrastructural and metabolic changes using in vivo 31p-nmr spectroscopy. | to assess the protective effect of verapamil on ischemic myocardium, the changes in high energy phosphates, inorganic phosphate, and intracellular ph were serially and quantitatively measured in ischemic porcine hearts without collateral circulation using 31p-nmr spectroscopy, together with ultrastructural examination. twenty-six farm pigs weighing 11 to 14 kg were anesthetized with fluothane and were divided into control (c) group and verapamil pretreatment (v) group. in v group 0.2 mg/kg of ve ... | 1990 | 2231744 |
| importance of acid-base strategy in reducing myocardial and whole body oxygen consumption during perfusion hypothermia. | during induced hypothermia with cardiopulmonary bypass, acid-base management usually follows one of two strategies: the so-called ectothermic or alpha-stat strategy, in which the ph of the arterial blood increases 0.015 ph units for every degree celsius decrease in body temperature, or the ph-stat strategy, in which ph remains 7.4 at all temperatures. it has been assumed that oxygen consumption decreases approximately equally during hypothermia with either strategy, although there are biochemica ... | 1990 | 2232832 |
| quantum type bone remodeling in the otic capsule of the pig. | normal quantum type bone remodeling was studied in temporal bones of young domestic pigs by means of combined microradiography, osteofluorochrome labelling and osteoid staining. evolving secondary osteons were morphologically normal although much less in the otic capsule than in the surrounding compacta of the temporal bones or in long bones. moreover, remodeling was totally absent in bone tissue immediately adjacent to perilymphatic spaces suggesting the presence of a local mechanism controllin ... | 1990 | 2239210 |
| postnatal development of the hair cycle in the domestic pig. | the postnatal patterns of hair follicle activity have been quantified in pigs born in summer and winter. animals were skin sampled monthly during the first year of life and the stages of the hair cycle were identified from follicles in histological sections. percentages of active follicles were used to determine hair cycle patterns and as a measure of how the hair cycle became synchronised with that of the adult. at birth, in excess of 95% of follicles were active in fibre production. within the ... | 1990 | 2254156 |
| meiotic chromosome behaviour reflects levels of sequence divergence in sus scrofa domestica satellite dna. | we present a general model for the evolution of chromosome-specific satellite dna subfamilies. sus scrofa domestica has a bimodal karyotype with two autosomal subsets of 12 meta-/submetacentric (mc) and 6 acrocentric (ac) chromosome types (mc and ac "subgenomes"). we show that the centromeric heterochromatin is characterised by two distinct satellite dna families designed mc1 and ac2. mc1 is a diverse satellite family of the mc subgenome of which certain members with a 100 bp repeat unit are fou ... | 1990 | 2265570 |
| [expression of constitutive heterochromatin by alui restriction endonuclease treatment and ca3/da/dapi staining of domestic pig chromosome]. | the heterogeneity of constitutive heterochromatin in two domestic pigs has been studied by restriction endonuclease alui banding, ca3/da/dapi banding and c-banding techniques. the results show that the centromere constitutive heterochromatin can be subdivided into three types, which located in different chromosomes. it is found that there is correspondence between no. 13--18 chromosomes in pigs and no. 1, 9, 16, y chromosome in human by comparing the banding patterns of alui and ca3/da/dapi. the ... | 1990 | 2268447 |
| hearing in domestic pigs (sus scrofa) and goats (capra hircus). | behavioral audiograms were determined for three pigs and two goats. the hearing of the pigs ranged from 42 hz to 40.5 khz with a region of best sensitivity from 250 hz to 16 khz. hearing in goats ranged from 78 hz to 37 khz with a well-defined point of best sensitivity at 2 khz. because these animals are unable to localize high-frequency tones, it seems unlikely that selective pressure to use the interaural spectral-difference cue for sound localization is behind their high-frequency hearing. in ... | 1990 | 2272932 |
| plasma concentrations of laudanosine, but not of atracurium, are increased during the anhepatic phase of orthotopic liver transplantation in pigs. | to quantify the changes in plasma concentrations of atracurium and laudanosine induced by the lack of hepatic function and circulation, the authors studied nine domestic pigs (22-25 kg) undergoing an orthotopic liver transplantation, and three control animals without surgery, using atracurium as the muscle relaxant. after intubation facilitated by isoflurane 2-3%, anesthesia was maintained with isoflurane (0.5% in oxygen) and fentanyl (4 micrograms.kg-1.hr-1). ventilation was controlled to keep ... | 1990 | 2297117 |
| postnatal developmental profile of 3-hydroxy-3-methylglutaryl-coa reductase, squalene synthetase and cholesterol 7 alpha-hydroxylase activities in the liver of domestic swine. | activities of 3-hydroxy-3-methylglutaryl-coa reductase, squalene synthetase and cholesterol 7 alpha-hydroxylase, measured in liver microsomal preparations from domestic swine between birth and adolescence, correlated strongly in individual animals. a synchronous increase was observed between 4 and 6 weeks after birth, i.e., immediately after weaning. rise in activity was highest for hmg-coa reductase (30-fold), and smallest for squalene synthetase (5-fold). in pubertal pigs (16 to 30 weeks old), ... | 1990 | 2297519 |
| atherosclerotic yucatan microswine: an animal model with high-grade, fibrocalcific, nonfatty lesions suitable for testing catheter-based interventions. | a new breed of swine, the yucatan microswine, that was derived from repetitive inbreeding of selected, small yucatan swine, was investigated as an animal model of advanced vascular atherosclerosis. nineteen animals were fed an atherogenic diet for 9.9 +/- 1.5 (mean +/- sem) weeks before and 19.9 +/- 1.8 weeks after balloon endothelial denudation of all four iliac arteries. in 18 (94.7%) of the 19 microswine, angiography performed at 33 to 87 weeks of age disclosed some degree of luminal diameter ... | 1990 | 2301218 |
| effects of physostigmine on the cardiopulmonary system of conscious pigs. | physostigmine, as a pretreatment candidate for nerve agent poisoning, was examined for cardiopulmonary side effects. cardiovascular and pulmonary parameters were monitored in unanesthetized domestic pigs which received pulmonary arterial infusion of 5 micrograms/kg/min physostigmine salicylate for 2 hr. a level of 74% inhibition of red blood cell (rbc) acetylcholinesterase (ache) activity was attained in 45 min, and this level of carbamylation increased only slightly during the remaining infusio ... | 1990 | 2307326 |
| second-degree burn healing: the effect of occlusive dressings and a cream. | because occlusive dressings and some creams have been found to speed epithelialization of blade-induced wounds, we studied the effect of two occlusive dressings and a polyglycerylmethacrylate cream containing low concentration of fibronectin on epithelialization in second-degree burn wounds. cylindrical brass rods were heated in a boiling water bath, removed, wiped dry, and placed (6 sec) on the skin of domestic pigs. the burned epidermis was removed and each burn wound was assigned to one of th ... | 1990 | 2314098 |
| cocaine hepatotoxicity in cultured liver slices: a species comparison. | studies were carried out in order to find a sensitive in vitro model with which to investigate cocaine-mediated hepatotoxicity. precision-cut liver slices were prepared from: human, domestic pig, new zealand white rabbit, sprague-dawley (s/d) rat, and two mouse strains (dba/2ha and icr). the rationale for the choice of these species was that information on in vivo effects of cocaine was available in the literature. slices were cultured for up to 6 h in the presence of 0-5 mm cocaine. indices of ... | 1990 | 2321245 |
| masseter muscle performance. significance of structure and metabolism. a morphological and experimental study. | the aim of this thesis was to characterize structural factors in masticatory systems relevant to functional evaluations and to elucidate the effect on energy metabolism of electrically induced jaw muscle fatigue. an omnivorous masticatory system (the domestic pig) was compared morphologically with a carnivorous (the dog). porcine masseter muscles were evaluated by atp-ase histochemistry as well as with nadh-dehydrogenase and pas-staining. contractional characteristics were obtained from the porc ... | 1990 | 2326743 |
| analysis of naturally occurring deletion variants of african swine fever virus: multigene family 110 is not essential for infectivity or virulence in pigs. | a comparison of uncloned african swine fever virus isolates with their cloned counterparts revealed the presence of genetic variants in three out of seven uncloned field virus populations tested. five different virus clones were isolated from the uncloned kir69 virus stock by limit dilution. structural analysis of the variants showed that they differed by single deletions of 10-16 kilobases in the region located between 6.8 and 27 kilobases from the left dna terminus. there was no homology betwe ... | 1990 | 2330671 |
| [crown wall thickness, external dimensions and solid pulp substance relationships of swine teeth]. | investigations had been carried out with 60 premolars of the upper and lower jaws in 2-year old domestic pigs in relation to their crown dimensions, their layer thickness of enamel and dentine. | 1990 | 2334060 |
| the purification and characterization of a fatty acid binding protein specific to pig (sus domesticus) adipose tissue. | western-blot analysis using antiserum to 3t3-l1-cell fatty acid binding protein (fabp) revealed that pig adipose tissue contains a 15 kda protein immunologically similar to the murine protein. this 15 kda protein was purified from pig adipose tissue by sequential application of sephadex g-50 gel filtration, cation exchange and covalent chromatography on thiol-sepharose-4b. the purity of the pig protein was established by two-dimensional polyacrylamide-gel electrophoresis. isoelectric focusing in ... | 1990 | 2334399 |
| [light and electron microscopic studies of the histopathogenicity of macracanthorhynchus hirudinaceus (archiacanthocephala) in experimentally infected domestic swine]. | one and 12 weeks after infection the lesions in the small intestine of two domestic pigs caused by macracanthorhynchus hirudinaceus were studied by means of light and electron microscopy. worms of 7 d.p.i. were found to have penetrated with their presoma into the tunica propria and partly into the tunica muscularis where they had caused local mechanic destructions and heavy eosinophilic-like and hemorrhagic reactions. most eosinophilic-like granulocytes were attracted to the proboscis hooks, at ... | 1990 | 2336449 |
| rapid ventricular pacing in pigs: an experimental model of congestive heart failure. | to develop an improved animal model of congestive heart failure, 11 female farm pigs (wt, 42-46 kg) underwent rapid ventricular pacing at 230 beats/min for 7 days with a modified medtronic unipolar pacemaker connected to an apical pacing lead. after 7 days the pacemaker was turned off, anesthesia induced, the chest opened, and cardiac hemodynamic and dimensional studies were performed. results were subsequently compared with data from 12 control pigs that received no pacing. two pigs died before ... | 1990 | 2337189 |
| electrocardiographic effects of experimental myocardial infarction in pigs. | myocardial infarctions were produced in young domestic farm pigs by ligating coronary arteries. arteries ligated in four groups were (a) left anterior descending, (b) branches of left anterior descending, (c) left circumflex, and (d) right coronary artery. after 7 or 8 days, the hearts were removed and dissected and the infarcted areas measured. vectorcardiograms were taken before ligation and just before termination. high recording speeds and sensitivities were used so that details of the qrs c ... | 1990 | 2341815 |
| neuronal and adrenal enkephalins and catecholamines in response to acute cns ischemia and reserpine in pig. | co-storage of enkephalins and catecholamines in coronary artery, mesenteric artery and vein, middle cerebral artery, vas deferens and adrenal medulla was studied in domestic pig (sus scrofa). responses to acute cns ischemia were correlated with time to peak plasma levels of central venous and adrenal vein outflow samples in controls, during reserpine treatment and after drug withdrawal. endogenous enkephalins are co-stored in chromaffin granules of adrenal epinephrine-type cells and large dense ... | 1990 | 2348053 |
| [the effect of large-faced cerebral meningeal fibroses on the development of hemispheric volume. experimental and morphometric studies of swine brains]. | alterations that occurred to the hemispheric structure as a result of experimentally induced meningeal fibrosis are reported in this paper. the rinsing function of cerebrospinal fluid was unilaterally stopped in the subarachnoidal space of domestic pigs by means of a viscous medium which contained soluble fatty acid salts. the animals were sacrificed 35 or 95 d after the experiments. series of frontal sections of both cerebral hemispheres were planimetrically measured to establish differences be ... | 1990 | 2356672 |
| the physiology of adaptation to small bowel resection in the pig: an integrated study of morphological and functional changes. | this study examined the adaptive response to extensive small intestinal resection in the juvenile domestic pig. control animals underwent an ileal transection with end-to-end anastomosis, whereas resected pigs had a resection of the mid-75% of the total small bowel length. animals were followed for 16 weeks. resected animals gained less weight than controls, with no significant difference in feed intake per unit animal weight. in vivo fat, protein, carbohydrate, and total energy absorption were ... | 1990 | 2359003 |
| measurement of mean circulatory filling pressure and vascular compliance in domestic pigs. | to measure mean circulatory filling pressure (pmcf), a balloon was placed in the right atrium of seven pentobarbital sodium-anesthetized open-chest pigs for transient occlusion of flow combined with mechanical transfer of blood from the arterial to the venous circulation. equilibration occurred within 6-8 s at a pressure at 12.3 +/- 0.3 (se) mmhg after a 2.9 +/- 0.2 ml/kg transfer of blood. in another group of pentobarbital sodium-anesthetized closed-chest pigs, acetylcholine (ach) was used to i ... | 1990 | 2360680 |
| [mortality by crushing in domestic pigs: study of the causes and their relationship to the time and the month of the year in the climatic conditions of cuba]. | in the course of 3 years a complex of 25,000 pigs were investigated once per week for the dead among the 398 sucking piglets, and in the case of losses due to crushing to death the type of lesions and the connection with diseases was investigated. of the piglets investigated, 88 were crushed to death (21.2%), among them 65 (73.8%) diseased--mainly infected by coli bacilli (60 = 68.2%)--and 23 (5.8%) healthy animals. the losses due to crushing to death were highest in january and differed from al ... | 1990 | 2360897 |
| temporomandibular synovial fluid pressure response to altered mandibular positions. | hydrostatic synovial fluid pressure within the superior aspect of the temporomandibular joint space of the growing pig, sus scrofa domesticus, was examined in response to various acute and chronic alterations of mandibular position. bilateral measurements of pressure were recorded with chronically implanted wick catheters in three 8-week-old pigs before and at the time of appliance placement and then at 2-day intervals until the animals were 20 weeks old. besides confirming the observations of a ... | 1990 | 2363402 |
| cholinergic regulation of resting coronary blood flow in domestic swine. | cholinergic vasoconstriction in vivo and the influence of resting cholinergic activity on basal coronary tone were investigated by measuring coronary blood flow, cardiac function, and blood gases during either acetylcholine injection, muscarinic receptor blockade, or vagal ligation, in open-chest chloralose-urethan-anesthetized swine. intracoronary injections of acetylcholine (0.5-3.0 micrograms) caused significant (p less than 0.05) dose-dependent reductions in coronary blood flow (19.0-75.5%) ... | 1990 | 2375397 |
| volumetric comparison of auditory structures in the brains of european wild boars (sus scrofa) and domestic pigs (sus scrofa f. dom.). | the size of certain brain parts involved in the processing of auditory stimuli was measured in european wild boars (sus scrofa) and domestic pigs (sus scrofa f. dom.). by means of intraspecific allometric methods for analyzing the brain weight to body weight relationships, the volumes were compared in both groups. in general, all measured structures were smaller in the domestic form, indicating that domestication has led to a decrease in the size of auditory brain parts. within the auditory syst ... | 1990 | 2375973 |
| immunocytochemical demonstration of the calcium-binding proteins calbindin-d 28k and parvalbumin in the subiculum, hippocampus and dentate area of the domestic pig. | the distribution of the calcium-binding proteins calbindin-d 28k (cabp) and parvalbumin (pv) in the hippocampal region of the domestic pig was demonstrated by immunocytochemistry. scattered cabp-immunoreactive cell bodies were present in the subiculum, stratum oriens, pyramidal cell layer and stratum radiatum of the hippocampal regio superior and inferior, and the outer plexiform layer and outer hilar cell layer of the dentate hilus. other cell bodies and bundles of stained fibers were present i ... | 1990 | 2392572 |
| endoscopic treatment of bronchus stump fistulae following pneumonectomy with fibrin sealant in domestic pigs. | occlusion of the transected bronchus after pneumonectomy was achieved by transthoracic fibrin sealing in 14 domestic pigs. in 9 additional animals standardized bronchus stump fistulae could also be closed with fibrin sealant which was applied through a flexible bronchoscope. an average of 1 ml of fibrin sealant containing 500 units of thrombin and 3500 units of aprotinin was necessary to achieve bronchial closure and to prevent early dissolution of the sealant. endoscopic closure of a bronchus f ... | 1985 | 2417369 |
| similar epidermal changes in hyperkeratotic scabies of humans and pigs. | we compared some morphological and biochemical aspects of the epidermal changes occurring in hyperkeratotic scabies in humans and domestic pigs. clinically and histologically, pig skin alterations look very similar to those observed in humans, i.e., brittle hyperkeratosis with parakeratotic crusting and thickening of the epidermis. parakeratosis seems to correspond to previous passage of scabies mites through the incompletely differentiated layers of the epidermis. indeed, by serial sectioning w ... | 1986 | 2425653 |
| conservation of diagnostic antigen epitopes among biologically diverse isolates of trichinella spiralis. | crude and immunoaffinity-purified excretory-secretory antigens derived from a domestic pig isolate of trichinella spiralis were used in an enzyme-linked immunosorbent assay to test serum from mice infected with 25 different pig and wild animal isolates of t. spiralis sspp. all of the sera were found positive by elisa using either of the antigen preparations, indicating all isolates shared certain antigen epitopes. excretory-secretory antigens were prepared from 3 distinct isolates of t. spiralis ... | 1986 | 2434638 |
| [effect of iloprost on aggregation behavior in kidney conditioning and changes in iloprost concentration in kidney preservation]. | the conditioning of the donor by 1.0 microgram/kg x min iloprost over 15 minutes leads to a considerable inhibition of the aggregation of thrombocytes in the domestic pig. 160% more adp had to be added than before the application of iloprost. when 0.5 microgram/ml iloprost are added to the perfusion fluid and to the reperfusion fluid 0.22 microgram/ml and 0.27 microgram/ml, respectively, are to be proved in the venous efflux. whether or not the difference is absorbed or metabolized must remain o ... | 1986 | 2437731 |
| epinephrine-induced premature ventricular contractions and changes in arterial blood pressure and heart rate during i-653, isoflurane, and halothane anesthesia in swine. | i653 is a new inhalation anesthetic having especially desirable recovery characteristics because of its very low blood and tissue solubility. investigations of its cardiovascular and electroencephalographic effects have revealed actions similar to those of isoflurane. however, these studies did not evaluate the potential of i653 to predispose the heart to epinephrine-induced arrhythmias. in this investigation, we studied eight domestic swine to compare the effects of i653 with those of other ane ... | 1989 | 2464293 |
| histochemical demonstration of zinc in the hippocampal region of the domestic pig: i. entorhinal area, parasubiculum, and presubiculum. | a detailed description is given of the distribution of zinc in three areas of the domestic pig hippocampal region, viz., the entorhinal area, the parasubiculum, and the presubiculum. zinc was demonstrated histochemically with use of the neo-timm method, a recent modification of the sulphide silver procedure. each of the studied areas showed a distinctly stratified staining pattern, which has been correlated in detail to fields and layers defined on the basis of cyto- and fibroarchitecture, provi ... | 1989 | 2477401 |
| prenatal development of the adrenal gland in the pig (sus scrofa domestica). part i. the differentiation and development of the adrenal cortex primordium in the first half of pregnancy. | the differentiation and development of the adrenal gland in pig embryos from 18 to 48 days of pregnancy were investigated with histological and histochemical methods and in electron microscope. primordia of the adrenal cortex appear at 21st day as two symmetrical streaks of the condensed mesenchymal cells between the mesonephros, aorta dorsalis and mesenterium. the capillaries and chromaffinoblasts penetrate the primordium. the mesenchymal cells differentiate into adrenal cortical cells. in the ... | 1989 | 2485767 |
| prenatal development of the adrenal in pig sus scrofa dom. part ii. adrenal cortex development in the second part of pregnancy. | the development of the adrenal cortex in pig fetuses between the 50 and 112 day of pregnancy were investigated with histological and histochemical methods and in electron microscope. three consecutive generations of the cortical cells were observed. they had features of steroidogenic cells and differed with mature of mitochondria and in amount of ser and in enzyme activity. the earliest differentiated fetal cortical cells demonstrated alkaline phosphatase activity and giant mitochondria. they we ... | 1989 | 2485783 |
| ultrastructural and histochemical investigations of the development of the medullary part of the adrenal gland in domestic pig (sus scrofa dom.) during the prenatal period. | the development of the adrenal medulla was investigated during the prenatal period in the pig. the observations were carried out on 221 embryos from 21 to 112 day post coitum. the histological, histochemical, ultrastructural and stereological methods were performed. first chromaffinoblasts infiltrated the adrenal cortex primordium around the 27-th day pc. they were mixed with cortical cells and just in the last days of pregnancy they were localized only in central part of adrenal. the chromaffin ... | 1989 | 2485784 |
| the ultrastructure of capillary walls and perivascular space of the pineal gland in three representatives of suidae species. | the ultrastructure of capillary vessels and the perivascular space (pvs) of the pineal gland were investigated in the domestic pig, miniature pig, and wild boar. it has been ascertained that the capillaries of these animals have continuous thick walls without pores and fenestrations. in fetal period, capillaries with spacious lumina, bordered by 3 to 4 endothelial cells predominate. the pvs, as a rule wide open, contain nerve endings, pinealocyte process endings, and collagenous fibers which inc ... | 1989 | 2485786 |
| spectral sensitivity of cones in an ungulate. | ungulates have been classified as having arrhythmic eyes in the sense that they contain features appropriate both to diurnal and nocturnal life. the former is typically associated with multiple classes of cones and a color-vision capacity. to see if an arrhythmic animal has these features, the number of cone classes was determined and the spectra of these cones were measured in a common ungulate, the domestic pig (sus scrofa). examination with electroretinogram (erg) flicker photometry revealed ... | 1989 | 2487648 |
| myocardial acidosis associated with co2 production during cardiac arrest and resuscitation. | previous studies from our institution demonstrated significant hypercarbic acidosis in the mixed venous (pulmonary artery) blood in animals and human patients during cardiac arrest and cardiopulmonary resuscitation (cpr). in the present study, the acid-base state of the myocardium during cardiac arrest was investigated. cardiac arrest was electrically induced in 11 pentobarbital-anesthetized and mechanically ventilated domestic pigs. precordial compression was begun 3 minutes after onset of vent ... | 1989 | 2504512 |
| myocardial potassium uptake during experimental cardiopulmonary resuscitation. | changes in myocardial k+ handling were examined during ventricular fibrillation and subsequent cpr in ten domestic swine. during ventricular fibrillation, there was initial k+ efflux from the myocardium which was followed by myocardial k+ uptake during precordial compression. after successful defibrillation, a washout in k+ was observed. coronary potassium clearance was inversely related to the myocardial [h+], pco2, and lactate production. a negative correlation between cardiac vein [k+] and my ... | 1989 | 2504539 |
| the effect of gas permeability of film dressings on wound environment and healing. | we have determined the effect of oxygen and carbon dioxide permeability of thin film dressings on wound exudate p o2, p co2, ph, and epithelialization in shallow wounds on domestic pigs. three kinds of films were compared: polyvinylidine chloride, a low gas permeability film; polyurethane, a medium gas permeability film; and poly(dimethyl silicone), a high gas permeability film. exudate under the silicone film had the highest p o2 and the lowest p co2; exudate under the polyurethane had intermed ... | 1989 | 2506289 |
| effect of zearalenone on early pregnancy in guinea pigs. | female guinea pigs were tested to determine whether they could serve as a model of zearalenone (zen) toxicosis during early pregnancy, as observed in domestic swine. only 1 of 4 female guinea pigs that were given 21 mg of zen/kg of body weight orally during the first 8 days after mating was pregnant when examined 22 days after mating. guinea pigs that were given 7 or 14 mg of zen/kg had normal fetal development. serum concentrations of progesterone were less than 12 ng/ml in all guinea pigs 8 an ... | 1989 | 2528930 |
| a survey of wild swine in the united states for evidence of hog cholera. | the results of surveillance for hog cholera (hc) in wild swine (sus scrofa) collected from throughout the united states from 1979 to 1987 are presented. sera collected from 1,218 wild swine and tissues from 637 were evaluated for hc antibodies and virus, respectively. included within this surveillance were samples from santa cruz and santa rosa islands, california, where hc virus had been deliberately introduced into wild swine during the 1950's in attempts to eradicate these animals. all evalua ... | 1989 | 2536850 |
| [estimation of the incidence of human trypanosomiasis due to trypanosoma brucei gambiense using epidemiological parameters essentially linked to the vector: case of a focus in the ivory coast]. | the entomo-epidemiological studies carried out from 1980 to 1985 in the human trypanosomiasis focus at bouaflé (ivory coast) were designed to estimate the main epidemiological parameters related to g. palpalis palpalis, the sleeping sickness vector in the zone considered. this paper defines the mathematical relationships which can exist between these parameters leading to the production of a simple model enabling estimates to be made of the incidence of human trypanosomiasis caused by t.b. gambi ... | 1989 | 2552942 |
| plasma catecholamines, ph, and blood pressure during cardiac arrest in pigs. | this study examined plasma epinephrine (e) and norepinephrine (ne) concentrations, ph, and mean arterial blood pressure (map) in a cardiac arrest model. twenty-three domestic swine (15-26 kg) were anesthetized with ketamine 20 mg/kg, i.m. and alpha-chloralose 25 mg/kg, i.v. and ventilated with a respirator. catheters were placed in the right ventricle, left ventricle and femoral arteries for map recordings and blood ph sampling every 2 min. catecholamine samples were taken from the femoral arter ... | 1989 | 2554447 |
| [effect of cysteinyl leukotrienes on uterine strips from pregnant and non-pregnant swine]. | cysteinyl leukotrienes c4, d4 and e4 elicited concentration-dependent contractile response of pregnant and non-pregnant pig uterine strips during incubation in de jalon solution in concentrations between 1 x 10(-9)m and 1 x 10(-5)m for ltc4 and ltd4, and between 1 x 10(-8)m and 1 x 10(-5)m for lte4. the maximum contractions elicited by leukotrienes were 77.5 +/- 3.0%, 86.0 +/- 2.6% and 37.5 +/- 2.5% of these elicited by histamine 1 x 10(-5)m for ltc4, ltd4 and lte4, respectively. fpl 55712, leuk ... | 1989 | 2562080 |
| porcine adrenal prolactin receptors: characterization, changes during neonatal development and effects of hypoprolactinemia. | 1. adrenal prolactin (prl) receptors were identified within the adrenal cortex of pigs (sus domesticus), and found to be located specifically on isolated zona fasciculata/reticularis cells (6437 sites per cell). 2. these prl receptors were associated with binding to [125i]-oprl which was characterized as being time and temperature dependent, specific for prl, saturable, of high affinity (ka = 10(10)/m) with a single class of binding sites, and irreversible except under extreme conditions. 3. the ... | 1989 | 2566410 |
| influence of various adrenergic compounds on plasma potassium levels in conscious dogs and anaesthetized domestic pigs. | the influence of various compounds with affinity to beta-adrenoceptors on plasma potassium levels was investigated in conscious dogs and anaesthetized pigs. there was a marked fall, amounting to about 1 mmol/l following salbutamol and pirbuterol but nearly no effect following dobutamine and xamoterol. in dogs the hypokalaemic effect of salbutamol was augmented when prazosin was additionally applied. it is concluded, that the plasma potassium level is reduced mainly by beta 2-adrenoceptor stimula ... | 1989 | 2576204 |
| a highly repeated sequence in the domestic pig: a gender-neutral probe. | | 1989 | 2602124 |
| histopathological features of unilateral stapling in animal experiments. | blount stapling of the proximal medial tibial growth was performed in 10-week-old domestic pigs. a total of 37 animals for up to 17 weeks were followed up. the histological evaluation showed a different reaction of the growth plate in the medial (stapled), central and lateral area. up to 6 days after stapling the morphological features were characterized by deviations of the cell column from the axial alignment. herniations of mature chondrocytes as well as isles of epiphyseal cartilage splinter ... | 1989 | 2619521 |
| effects of fluoride on cortical bone remodeling in the growing domestic pig. | the purpose of the experiment was to assess the effects of fluoride (f-) on the remodeling process of cortical bone. sixteen pigs, eight experimental animals receiving a supplement of 2 mg f-/kg b.w. and eight controls, were studied in individual sites from age 8 to 14 months. at slaughter samples of cortical bone were obtained from the right femur and embedded undecalcified. a new stereologic model based on fluorochrome tissue time markers and isotropic uniform random histologic sections was im ... | 1989 | 2624822 |