| molecular features of the tspy gene of gibbons and old world monkeys. | restriction pattern, chromosome localization and the sequence of the testis-specific gene, tspy, were investigated in the white-handed gibbon, agile gibbon, siamang, hamadryas baboon and japanese monkey. southern blot analysis showed the tspy gene to be male specific in the primates used and disclosed variability of restriction pattern in gibbons. fluorescence in situ hybridization demonstrated that the probe pptspy2372, biotinylated using polymerase chain reaction, is located as a slight signal ... | 1996 | 8939361 |
| divergent simian t-cell lymphotropic virus type 3 (stlv-3) in wild-caught papio hamadryas papio from senegal: widespread distribution of stlv-3 in africa. | among eight samples obtained from a french primatology research center, six adult guinea baboons (papio hamadryas papio), caught in the wild in senegal, had a peculiar human t-cell leukemia virus type 2 (htlv-2)-like western blot seroreactivity (p24(+), gd21(+), k55(+/-)). partial sequence analyses of the tax genes (433 bp) indicated that these baboons were infected by a novel divergent simian t-cell lymphotropic virus (stlv). analyses of the complete proviral sequence (8,892 bp) for one of thes ... | 2003 | 12477886 |
| organization of the epaxial muscles in terrestrial and arboreal primates. | the erector spinae muscles of the patas monkey hamadryas baboon, and spider monkey were dissected and the origins and insertions were described in detail. in the two terrestrial monkeys, a well-developed thoracolumbar segment of the muscle was observed. this trait seems to correlate to the sagittal movement of this region required in the pronograde quadrupedal locomotion. on the other hand, the erector spinae muscle of the spider monkey is quantitatively not so well developed and the arrangement ... | 1996 | 8953747 |
| low-dose nitro-l-arginine administration in baboon (papio hamadryas) pregnancy. | 1. the purpose of the present study was to examine the effect of nitric oxide (no) inhibition on mean arterial pressure (map), endothelin (et) and the renin-aldosterone system in pregnancy in the non-human primate (baboon). 2. twenty pregnant baboons (papio hamadryas) were examined prospectively after the administration of an oral no inhibitor in different phases of pregnancy. haemodynamic responses to no inhibition, evidence of pre-eclampsia and the renin-aldosterone system were examined under ... | 1999 | 10561803 |
| pollical oblique ligament in humans and non-human primates. | a morphological study of the oblique ligament in the thumb is presented. the ligament was consistently described in human specimens and compared with dissections of non-human primates from different species. the oblique ligament was found in some, but not all, specimens in each of the following species examined: chimpanzee, orangutan, gibbon, anubis baboon, hamadryas baboon, squirrel monkey, lemur and marmoset. a revised identity of the oblique ligament is proposed as a reinforced distal border ... | 2003 | 12739617 |
| immune and pathophysiological processes in baboons experimentally infected with ebola virus adapted to guinea pigs. | the dynamics of pathophysiological and immunological parameters monitored in monkeys papio hamadryas infected with the guinea pig-adapted ebola virus strain demonstrated that this viral strain preserved its virulence for monkeys and caused the disease with characteristic features similar to those caused by non-adapted ebola virus. however, certain previously unknown patterns have been observed: (1) prolongation of the febrile period by two days; (2) extended period was characterized by stability ... | 2000 | 10714441 |
| filamentous tau pathology in nerve cells, astrocytes, and oligodendrocytes of aged baboons. | intracellular filamentous inclusions containing abnormally phosphorylated tau protein are hallmarks of several human neurodegenerative disorders. this study reveals tau-positive cytoskeletal abnormalities in neurons and glial cells of aged baboons. the brains of four baboons (papio hamadryas, 20-30 yr of age) were examined using the gallyas silver technique for neurofibrillary changes and phosphorylation-dependent anti-tau antibodies (at8, at100, at270, phf-1, tg-3). conspicuous changes were not ... | 2000 | 10744034 |
| absence of evidence of infection with divergent primate t-lymphotropic viruses in united states blood donors who have seroindeterminate htlv test results. | recent identification of divergent simian or primate t-lymphotropic viruses (stlvs; ptlvs) in bonobos (formerly called pygmy chimpanzees; pan paniscus; viruses: stlvpan-p and stlvpp1664) and a baboon (papio hamadryas; viruses: stlvph969 or ptlv-l) have raised the possibility of human infection with these viruses. divergent ptlv-infected primate sera show p24 bands on htlv-i western blots (wbs). it was investigated whether infection by divergent ptlv-like viruses could explain a subset of united ... | 2000 | 10773057 |
| a genetic linkage map of the baboon (papio hamadryas) genome based on human microsatellite polymorphisms. | a first-generation genetic linkage map of the baboon (papio hamadryas) genome was developed for use in biomedical and evolutionary genetics. pedigreed baboons (n = 694) were selected from the breeding colony maintained by the southwest foundation for biomedical research. to facilitate comparison with the human genome, the baboon linkage map consists primarily of human microsatellite loci amplified using published human pcr primers. genotypes for 325 human microsatellites and 6 novel baboon micro ... | 2000 | 10936045 |
| pregnancy-specific glycoprotein (psg) in baboon (papio hamadryas): family size, domain structure, and prediction of a functional region in primate psgs. | pregnancy-specific glycoprotein (psg) constitutes a major component of serum of pregnant women and appears to be essential for a successful pregnancy. its function is, however, still unknown. because of the evolutionary divergence between human and rodent psg, functional studies may require a primate animal model. we have characterized psg transcripts in a baboon placenta cdna library and analyzed baboon genomic dna. the main psg isoform had the domain structure n-a1-b2-c similar to the human ty ... | 2001 | 11133662 |
| high prevalence of simian t-lymphotropic virus type l in wild ethiopian baboons. | simian t-cell leukemia viruses (stlvs) are the simian counterparts of human t-cell leukemia viruses (htlvs). a novel, divergent type of stlv (stlv-l) from captive baboons was reported in 1994, but its natural prevalence remained unclear. we investigated the prevalence of stlv-l in 519 blood samples from wild-living nonhuman primates in ethiopia. seropositive monkeys having cross-reactive antibodies against htlv were found among 22 out of 40 hamadryas baboons, 8 of 96 anubis baboons, 24 of 50 bab ... | 2002 | 11799159 |
| effectiveness of human microsatellite loci for assessing paternity in a captive colony of vervets (chlorocebus aethiops sabaeus). | microsatellite polymorphisms are playing an increasingly vital role in primatological research, and are particularly useful for paternity exclusion in both wild and captive populations. although vervet monkeys (chlorocebus aethiops) are commonly studied in both settings, few previous studies have utilized microsatellite markers for assessing genetic variation in this species. in a pilot project to assess paternity in the ucla-va vervet monkey research colony (vmrc), we screened 55 commercially a ... | 2002 | 11948640 |
| composition of psoas major muscle fibers compared among humans, orangutans, and monkeys. | in primate species the m. psoas major, the only muscle simultaneously controlling the spinal column and lower extremity, is expected to reflect morpho-functional adaptation to diversified locomotor behavior. by using histochemical analysis with sudan black b staining, composition of different types of muscle fibers in the psoas major was compared between 2 japanese macaques, 2 hamadryas baboons, 2 anubis baboons, 2 orangutans, and 17 humans. the comparison has revealed unique features of this mu ... | 2002 | 12050900 |
| the aging baboon: comparative demography in a non-human primate. | why do closely related primate genera vary in longevity, and what does this teach us about human aging? life tables of female baboons (papio hamadryas) in two wild populations of east africa and in a large captive population in san antonio, texas, provide striking similarities and contrasts to human mortality patterns. for captive baboons at the southwest foundation for biomedical research, we estimate the doubling time of adult mortality rate as 4.8 years. wild females in free-living population ... | 2002 | 12082185 |
| apocrine glands in the eyelid of primates contribute to the ocular host defense. | apocrine glands of moll are regular components of primate eyelids. we studied the distribution and localization of these glands in three different primate species, the common marmoset, the rhesus monkey, and the hamadryas baboon. in addition, we tested the primate glands of moll with antibodies against antimicrobial proteins, cytoskeletal proteins and the androgen receptor. the glands of moll differ in abundance and distribution in different monkeys. in the common marmoset, a representative of t ... | 2004 | 15118398 |
| [a comparative description of amyloidosis in monkeys]. | the paper contains the results of a postmortem study of 461 cases of amyloidosis in monkeys of 4 species (papio hamadryas, macaca mulatto, macaca fascicularis and macaca nemestrina) from the sukhumi and adler primatological facilities. emergence of amyloidosis was found to be dependent on age; the frequency ratio at which separate organs are affected is presented; the specific disease signs are described for different monkey species. generalized and isolated cases of amyloidosis are elucidated w ... | 2004 | 15154328 |
| age-related endocrine dysfunction in nonhuman primates. | peculiarities of functioning of some parts of the endocrine system (the pineal gland, pancreatic gland, hypothalamic-pituitary-adrenal axis, and hypothalamic-pituitary-testicular axis) in an aging nonhuman primate model (papio hamadryas and macaca mulatta) are described in this article. it has been established that basal activity of some endocrine functions (glucocorticoid, corticotropic, pancreatic, male estradiol producing) varies little with age. other functions significantly decrease (dhea/d ... | 2004 | 15247036 |
| the effects of aminoguanidine on renal changes in a baboon model of type 1 diabetes. | the efficacy of aminoguanidine (ag) on primary prevention of diabetic nephropathy was investigated in a nonhuman primate model of type 1 diabetes over a period of 4 years. | 2002 | 12126789 |
| ranging behavior, group size and behavioral flexibility in ethiopian hamadryas baboons (papio hamadryas hamadryas). | this study reports group size, home range size, daily path lengths, seasonal effects on ranging behavior and qualitative information on diet for a population of hamadryas baboons inhabiting the lowlands of the northern rift valley in central ethiopia. the minimum home range size and daily path length for this population are similar to those reported for other populations of hamadryas baboons in ethiopia and saudi arabia. group sizes, however, are much larger than those in most other hamadryas po ... | 2002 | 12207056 |
| questions on the evolution of primate t-lymphotropic viruses raised by molecular and epidemiological studies of divergent strains. | in human and simian t-lymphotropic viruses (htlv and stlv), collectively referred to as primate t-lymphotropic viruses (ptlv), four distinct clades can be distinguished: ptlv-i, ptlv-ii, and the newly discovered divergent stlvs isolated from hamadryas baboons and from bonobos (pygmy chimpanzees). the hamadryas stlv is clearly distinct from types i and ii, in terms both of sequence divergence and of genomic structure, and would qualify as a separate type, provisionally called ptlv-l. the bonobo s ... | 1996 | 8797730 |
| precision grips, hand morphology, and tools. | this study asks whether there are discernable links between precision gripping, tool behaviors, and hand morphology in modern hominoids, which may guide functional interpretation of early hominid hand morphology. findings from a three-pronged investigation answer this question in the affirmative, as follows: (1) experimental manufacture of early prehistoric tools provides evidence of connections between distinctive human precision grips and effective tool making. (a connection is not found betwe ... | 1997 | 9034041 |
| conservation of human chromosome 18 in baboons (papio hamadryas): a linkage map of eight human microsatellites. | a panel of 25 microsatellite loci known to map to human chromosome 18 was screened for length polymorphisms in a multigenerational pedigree of baboons (papio hamadryas). eight of these loci were polymorphic in the baboon pedigrees, with observed heterozygosity values ranging from 0.16 to 0.88. all eight loci show strong evidence of linkage. the most likely map order among the microsatellite loci for papio is completely compatible with the locus order found in the human genome, and sex difference ... | 1996 | 9067425 |
| simian t-lymphotropic virus type 1 (stlv-1) infection in wild yellow baboons (papio hamadryas cynocephalus) from mikumi national park, tanzania. | serum and peripheral blood leukocytes from wild yellow baboons (papio hamadryas cynocephalus) were tested for the presence of stlv-1-specific antibodies and proviral dna. fourteen of 30 sera tested positive by radioimmunoprecipitation assay (ripa) with htlv-1. among 36 dna samples tested by pcr 15 were positive by double nested pcr for a fragment of the stlv-1 env gene, the most sensitive assay among pcr tests employed. of 30 animals that were tested both serologically and by pcr in only 1 case ... | 1997 | 9123842 |
| hormonal correlates of changes in interest in unrelated infants across the peripartum period in female baboons (papio hamadryas anubis sp.). | in past research on human and nonhuman primates, maternal responsiveness and behavior has been thought of as an experiential, cognitive mechanism; however, recent findings have shown that maternal motivation and behavior may not be entirely divorced from the endocrine system. to investigate the relationship between interest in infants and the hormonal changes related to pregnancy, we examined the nature of social interactions across parturition between a large sample (n = 133) of adult female ba ... | 2004 | 15555493 |
| ontogenetic bases of canine dimorphism in anthropoid primates. | this study tests hypotheses regarding the ontogeny of canine tooth size dimorphism in five anthropoid primate species (saguinus fuscicollis, macaca mulatta, cercocebus atys, papio hamadryas, and mandrillus sphinx). canine measurements and chronological age data are analyzed to determine if bimaturism, a sex difference in the age at which eruption ceases, accounts for canine tooth sexual dimorphism. canine height measurements are evaluated through a variety of regression techniques. results show ... | 2005 | 15584072 |
| complete nucleotide sequence of the new simian t-lymphotropic virus, stlv-ph969 from a hamadryas baboon, and unusual features of its long terminal repeat. | a third type of primate t-lymphotropic virus, ptlv-l, with stlv-ph969 as a prototype, has recently been isolated from an african baboon (papio hamadryas). classification of this virus has been based on partial sequence analysis of cdna from a virus-producing cell line, ph969. we obtained the complete nucleotide sequence of this virus with a proviral genome of 8,916 bp. all major genes, homologous in all human t-cell lymphotropic virus (htlv)-related viruses, and their corresponding mrnas, includ ... | 1997 | 9188619 |
| interleukin-10 regulates arterial pressure in early primate pregnancy. | in pregnancy, the placental contribution of cytokines to maternal immunosuppression has been established, however their role in normal maternal blood pressure regulation has not been identified. we investigate the contribution of interleukin-10 (il-10) and tumor necrosis factor-alpha (tnf-alpha) to the vasodilation of early pregnancy in non-human primates. we also sequenced the il-10 baboon gene and compared it with humans. | 2004 | 15652450 |
| omental anatomy of non-human primates. | the anatomy and physiology of the omentum provide optimum reconstructive characteristics and the omentum may be used as a free or pedicled autograft, but also as the receptor site for engraftment of glandular islets. our purpose was the study of the omental anatomy of non-human primate (nhp), in order to determine an experimental model for pancreatic islets transplantation. seventeen cadavers nhp (age range 4 years to 23 years) were utilised in this anatomical study. both cynomolgus monkeys (mac ... | 2005 | 16237487 |
| [follow-up study of the evolution of the quantitative eeg in intraventricular infusion of nerve growth factor in an aged baboon]. | the animal model of aged monkeys is a good homologue of alzheimer's disease in humans, in which it has been shown that there is disproportionate slowing of the eeg when compared with healthy subjects paired for age. this is found both on the conventional eeg and quantitatively. in the latter, relative energy has been the measurement most commonly used for diagnosis and follow-up with various treatments. the follow-up parameters evaluated in this study were: absolute and relative energy of the qu ... | 1997 | 9244612 |
| leveraging human genomic information to identify nonhuman primate sequences for expression array development. | nonhuman primates (nhps) are essential for biomedical research due to their similarities to humans. the utility of nhps will be greatly increased by the application of genomics-based approaches such as gene expression profiling. sequence information from the 3' end of genes is the key resource needed to create oligonucleotide expression arrays. | 2005 | 16288651 |
| androgen effects on bioactive and immunoreactive gonadotrophin levels during puberty in male baboons. | the effect of androgens on changes in circulating lh and fsh during pubertal development was examined longitudinally in a 3 year study in male hamadryas baboons. baboon lh and fsh were measured by a species-specific radioimmunoassay and bioactive lh (b-lh) was measured by the mouse in vitro leydig cell bioassay. control baboons (n = 5) progressed normally through puberty. eight baboons were castrated prepubertally; of these four received testosterone implants at the chronological age (ca) of cli ... | 1997 | 9364367 |
| baboon/human homologies examined by spectral karyotyping (sky): a visual comparison. | baboon (papio hamadryas) metaphase chromosomes were analyzed using spectral karyotyping (sky), a technique combining fluorescence microscopy, ccd-imaging, and fourier spectroscopy. results from a comparison of sky analyses using probes derived from human chromosomes on baboon metaphases were consistent with the majority of comparative gene mapping data between the two species. these data were also compatible with earlier studies comparing macaque and human chromosomes. human (hsa) chromosome 2 w ... | 1998 | 9763666 |
| low y chromosome variation in saudi-arabian hamadryas baboons (papio hamadryas hamadryas). | it is important to characterise the amount of variation on the mammalian y chromosome in order to assess its potential for use in evolutionary studies. we report very low levels of polymorphism on the y chromosome of saudi-arabian hamadryas baboons, papio hamadryas hamadryas. we found no segregating sites on the y, despite sequence analysis of 3 kb noncontiguous intron sequence in 16 males with divergent autosomal microsatellite genotypes, and a further analysis of 1.1 kb intron sequence in 97 m ... | 2006 | 16508662 |
| imaging dopamine d4 receptors in the living primate brain: a positron emission tomography study using the novel d1/d4 antagonist [11c]sdz glc 756. | the dopamine d4 receptor has lately attracted interest since it has been hypothesized to be involved in the pathogenesis and pharmacotherapy of neuropsychiatric diseases. the present study provides first in vivo evidence of dopamine d4 receptors in primate brain using a [11c]benzo[g]quinoline, the novel radioligand [11c]sdz glc 756 ([11c]glc: in vitro dissociation constants at human receptor clones [nm]: 1.10 at d1; 0.40 at d2; 25 at d3; 0.18 at d4.2; 6.03 at d5). dynamic positron emission tomog ... | 1998 | 9826226 |
| jejunal intussusception and small bowel transmural infarction in a baboon (papio hamadryas anubis). | a 4.3-y-old, colony-bred female baboon (papio hamadryas anubis) of low social rank and exhibiting no clinically significant signs of illness or distress was found dead at the oklahoma university health sciences center baboon breeding facility at el reno, ok. prior to death she exhibited excessive grooming behavior both toward herself and other baboons. in addition, she was consistently shy, timid, reclusive, and prone to minimal sustained movement (that is, generally lethargic behavior). animals ... | 2006 | 16542042 |
| behavioural and hormonal responses to predation in female chacma baboons (papio hamadryas ursinus). | in humans, bereavement is associated with an increase in glucocorticoid (gc) levels, though this increase can be mitigated by social support. we examined faecal gc levels and grooming behaviour of free-ranging female baboons to determine whether similar effects were also evident in a non-human species. females who lost a close relative experienced a significant increase in gc levels in the weeks following their relative's death compared with the weeks before, whereas control females showed no su ... | 2006 | 16608690 |
| verreaux's eagles (aquila verreauxi) as potential predators of hamadryas baboons (papio hamadryas hamadryas) in eritrea. | in this paper we describe for the first time encounters of verreaux's eagle (aquila verreauxi) with hamadryas baboons (papio hamadryas hamadryas) in the central highlands of eritrea (15 degrees 22' n, 38 degrees 58' e, 2300 m). during 12 h of observation on 4 days, we observed four encounters of verreaux's eagles with baboons, of which three can be classified as possible attacks. the baboons always responded with alarm calls. in three cases some immatures rushed to adult group members and clung ... | 1999 | 9888722 |
| [growing divergence inside primate t cell lymphotropic viruses]. | during our studies on the evolution of the ptlvs, we have isolated and genomically characterized two divergent simian t-lymphotropic viruses, not belonging to the previously well-established ptlv lineages. stlv-ph969 has been isolated from an eritrean sacred baboon (papio hamadryas), with an htlv-like indeterminate serological profile. the entire 8916 nt long genomic sequence, was obtained from a cdna library of ph969 mrna, in combination with a pcr based strategy. all open reading frames (orf) ... | 1999 | 10379197 |
| [immunogenicity of b-antigen in experimental plague and pseudotuberculosis]. | the results of the evaluation of the immunogenic properties of b-antigen, earlier identified in the culture fluid of yersinia pseudotuberculosis submerged culture, with respect to experimental plague and pseudotuberculosis are presented. b-antigen has been shown to produce protective effect in guinea pigs and, probably, hamadryas baboons, but not in white mice infected with the causative agent of plague. immunizaton with b-antigen protects guinea pigs from primary pneumonic plague caused by both ... | 2006 | 16830590 |
| functional morphology of the first cervical vertebra in humans and nonhuman primates. | the cervical vertebral column bears or balances the weight of the head supported by the nuchal muscles that partly originate from the cervical vertebrae. the position of the head relative to the vertebral column, and consequently locomotion and posture behavior, could thus be associated with the form of the cervical vertebrae. in spite of this assumption and some empirical indications along these lines, primate vertebral morphologies have been reported to be very similar and not clearly related ... | 2006 | 16955497 |
| alpha-defensins from blood leukocytes of the monkey papio hamadryas. | three antimicrobial peptides named phd1-3 (papio hamadryas defensin) have been isolated from hamadryas baboon blood leukocytes using preparative electrophoresis and reverse-phase hplc. the primary structures of these peptides have been determined by automated edman degradation and mass-spectrometry. the results suggest that the peptides belong to the alpha-defensin family. structural homology analysis reveals that among alpha-defensins from other animal species, phd3 is the most closely related ... | 2006 | 16978151 |
| repeat expansion in spinocerebellar ataxia type 17 alleles of the tata-box binding protein gene: an evolutionary approach. | the variability and mutational changes of the cag microsatellite in the tata-box binding protein gene (tbp) were studied. we sequenced the microsatellite of the tbp gene of 25 unrelated individuals from northern germany (10 sca17 patients and 15 unaffected control individuals). in addition, the microsatellites were sequenced from individuals of 10 northern german families with at least one family member affected by sca17. to study also the evolutionary history of this cag/caa microsatellite in n ... | 2007 | 17033685 |
| numerity of a socially housed hamadryas baboon (papio hamadryas) and a socially housed squirrel monkey (saimiri sciureus). | to extend a study conducted by e. m. brannon and h. s. terrace (1998, 2000), the authors trained 1 hamadryas baboon (papio hamadryas) and 1 squirrel monkey (saimiri sciureus) to respond to stimuli representing the numerosities 1-4 in ascending order. when tested with novel stimuli of the same numerosities, both subjects' performance appeared to be based on the numerical attributes of stimuli. subjects were then tested on their ability to order pairs of numerosities derived from the values 1-9. b ... | 2003 | 12856792 |
| trisomy 17 in a baboon (papio hamadryas) with polydactyly, patent foramen ovale and pyelectasis. | trisomy 13 in humans is the third most common autosomal abnormality at birth, after trisomy 21 and trisomy 18. it has a reported incidence of between 1:5,000 and 1:30,000 live births. it is associated with multiple abnormalities, many of which shorten lifespan. we describe here the first reported case of a baboon (papio hamadryas) with trisomy of chromosome 17, which is homologous to human chromosome 13. the trisomic infant was born to a consanguineous pair of baboons and had morphological chara ... | 2007 | 17330307 |
| studies on spontaneous primary encephalitides in the monkey. i. a polio-encephalitis with predilection for the brain stem in the baboon (papio hamadryas). | | 1959 | 13642086 |
| comparison of propofol and isoflurane anesthesia in orthotopic pig-to-baboon cardiac xenotransplantation. | orthotopic pig-to-baboon xenogeneic heart transplantation (oxhtx) is the only accepted preclinical animal model for cardiac xenotransplantation. we compared the hemodynamic stability of a propofol- and isoflurane-based anesthetic regimen during oxhtx. | 2007 | 17489866 |
| experimental infection of hamadryas baboons papio hamadryas with a human isolate of schistosoma mansoni from saudi arabia. | | 1992 | 17588039 |
| middle pleistocene fossil cercopithecidae from asbole, afar region, ethiopia. | a sample of 117 fossil cercopithecids has been collected from the middle pleistocene site of asbole, afar region, ethiopia. a minimum of five species is present. there are two species of cercopithecini, here recognized as cf. chlorocebus aff. aethiops, and cf. chlorocebus cf. patas. there are also two species of papionini: papio hamadryas ssp. indet. and theropithecus oswaldi leakeyi. finally, there is a single species of colobine present, colobus sp. indet. the assemblage is chronologically con ... | 2007 | 17658583 |
| reduced reproductive function in wild baboons (papio hamadryas anubis) related to natural consumption of the african black plum (vitex doniana). | several authors have suggested that the consumption of plant compounds may have direct effects on wild primate reproductive biology, but no studies have presented physiological evidence of such effects. here, for two troops of olive baboons (papio hamadryas anubis) at gashaka-gumti national park, nigeria, we show major seasonal increases in levels of fecal progesterone metabolites in females, and provide evidence that this is linked to the consumption of natural plant compounds. increases in fec ... | 2007 | 17681506 |
| studies on spontaneous primary encephalitides in the monkey. ii. encephalitis with a cortico-striate predilection in the baboon (papio hamadryas). | | 1959 | 13642087 |
| [on the "hybrid" antigen in monkeys (theropithecus gelada x papio hamadryas)]. | | 1963 | 14077733 |
| gene expression profiling of alcoholic liver disease in the baboon (papio hamadryas) and human liver. | the molecular pathogenesis of alcoholic liver disease (ald) is not well understood. gene expression profiling has the potential to identify new pathways and altered molecules in ald. gene expression profiles of ald in a baboon model and humans were compared using dna arrays. reverse transcriptase-polymerase chain reaction and immunohistochemistry were used for downstream analysis of array results. cdna array analysis revealed differential expression of several novel genes and pathways in additio ... | 2003 | 14633604 |
| bone mineral density reference standards in adult baboons (papio hamadryas) by sex and age. | osteoporosis is a progressive condition involving structural deterioration of bone tissue, leading to skeletal fragility and an increased susceptibility to fractures due to low bone mass and high rates of bone turnover. areal bone mineral density (abmd) serves as the most reliable predictor of susceptibility to osteoporotic fracture. the development of animal models, including old world monkeys, has been essential to studies of bone mineral density. these animals, including the baboon, exhibit m ... | 2003 | 14678847 |
| sequence-specific analysis of microchimerism by real-time quantitative polymerase chain reaction in same-sex nonhuman primates after islet and bone marrow transplantation. | accurate and sensitive detection of microchimerism in nonhuman primates (nhps) after hematopoietic cell transplantation is essential for monitoring cell engraftment, for evaluating the success of transplant protocols, and for expanding the utility of nhp in transplantation studies. because limited sequences are available for nhp major histocompatibility complex polymorphic loci, methods that can accurately determine low levels of donor cells in recipients with same-sex bone marrow transplantatio ... | 2007 | 18165781 |
| maternal parity affects neonatal survival rate in a colony of captive bred baboons (papio hamadryas). | non-human primates, particularly baboons, are valuable as animal models for reproductive research, because of their similarity to humans. knowledge of colony-specific pregnancy and neonatal outcomes is essential for interpretation of such research. | 2008 | 18194221 |
| gastroesophageal reflux disease in baboons (papio sp.): a new animal model. | gastroesophageal reflux disease (gerd) is increasingly prevalent in the human population. current animal models require surgical or other manipulation to produce symptoms. an animal model that exhibits spontaneous gerd would provide the opportunity for much-needed research examining the susceptibility, diagnosis, and treatment of gerd. | 2008 | 18199068 |
| [identification of clinical isolates of burkholderia cepacia and assessment of their pathogenicity in animal experiments]. | in experiments on animals study of pathogenicity of 9 clinical strains of burkholderia cepacia isolated from patients with chronic lung diseases was performed. preliminary identification of studied strains by means of biochemical and genetic methods allowed to establish their belonging to b. cepacia species. it was determined that 6 of 9 strains are epidemiologically significant. experiments showed that bacteria of studied strains are not able to cause infectious process in white mice and hamadr ... | 2008 | 18597993 |
| trypanosoma cruzi in non-human primates with a history of stillbirths: a retrospective study (papio hamadryas spp.) and case report (macaca fascicularis). | congenital transmission of trypanosoma cruzi has been described in humans and experimental work has been conducted with mice, but not with non-human primates (nhps). | 2008 | 18671769 |
| a quantitative method for the evaluation of three-dimensional structure of temporal bone pneumatization. | temporal bone pneumatization has been included in lists of characters used in phylogenetic analyses of human evolution. while studies suggest that the extent of pneumatization has decreased over the course of human evolution, little is known about the processes underlying these changes or their significance. in short, reasons for the observed reduction and the potential reorganization within pneumatized spaces are unknown. technological limitations have limited previous analyses of pneumatizatio ... | 2008 | 18715622 |
| the effect of aging on the immunohistochemistry of apolipoprotein e in the liver. | apolipoprotein e (apoe) is involved in hepatic disposition of chylomicron remnants, which is impaired in old age. isoforms of apoe have been implicated in age-related diseases and possibly the aging process itself. because the effects of old age on expression and distribution of apoe in the liver have not been reported, we studied the effect of old age on the immunohistochemistry of apoe in the livers of humans and the non-human primate, papio hamadryas. overall, old age was not associated with ... | 2004 | 14724064 |
| network scaling reveals consistent fractal pattern in hierarchical mammalian societies. | recent studies have demonstrated that human societies are hierarchically structured with a consistent scaling ratio across successive layers of the social network; each layer of the network is between three and four times the size of the preceding (smaller) grouping level. here we show that similar relationships hold for four mammalian taxa living in multi-level social systems. for elephant (loxodonta africana), gelada (theropithecus gelada) and hamadryas (papio hamadryas hamadryas) baboon, succ ... | 2008 | 18765349 |
| habitual cave use and thermoregulation in chacma baboons (papio hamadryas ursinus). | the willingness to utilise caves as shelters is held to have been important to early humans but dependent on pyrotechnology. despite anecdotal evidence that non-human primates will also exploit caves there has as yet been no detailed account of such exploitation or of the reasons underlying it. here we provide the first such data, on the frequency and patterning of the use of an underground cave system by baboons (papio hamadryas)-and show that usage is determined, at least in part, by above-gro ... | 2004 | 14871563 |
| flow cytometric sorting of frozen-thawed spermatozoa in sheep and non-human primates. | research was conducted in sheep to determine an effective preparation method for high-purity sorting of frozen-thawed spermatozoa. the efficacy of sorting frozen-thawed spermatozoa was then investigated in several non-human primate species. an aliquot of each ejaculate (three rams, three ejaculates per ram) was processed as a fresh control (fresh). frozen spermatozoa were thawed and prepared for sorting by no further processing (ft-neat), washing (ft-wash) or gradient centrifugation (ft-gradient ... | 2003 | 14984693 |
| the baboon model (papio hamadryas) of fetal loss: maternal weight, age, reproductive history and pregnancy outcome. | several risk factors are associated with the incidence of human stillbirths. the prevention of stillbirths in women is a pressing clinical problem. | 2008 | 19017195 |
| incidence of lymphoma in a captive-bred colony of hamadryas baboons (papio hamadryas). | to assess the incidence of lymphoma and wasting-related deaths in the national baboon colony of australia and relate it to the presence of simian t-cell lymphotrophic virus 1 (stlv-1) infection. | 2009 | 19489781 |
| immunophenotypical characteristics of permanent cultures of lymphoid cells from papio hamadryas and macaca arctoides. | immunophenotypical characteristics of primate cells were studied by enzyme immunoassay and flow cytofluorometry using a panel of monoclonal antibodies to human b- and t-lymphocyte antigens. specific features of immunophenotype of cultured cells were detected. simian lymphoid cultures consist of a mixture of b- and t-cells with mosaic antigenic structure expressing markers of b and t cell specificity. | 2004 | 15273772 |
| crossing the red sea: phylogeography of the hamadryas baboon, papio hamadryas hamadryas. | the hamadryas baboon (papio hamadryas hamadryas) is found both in east africa and western arabia and is the only free-ranging nonhuman primate in arabia. it has been hypothesized that hamadryas baboons colonized arabia in the recent past and were possibly even transported there by humans. we investigated the phylogeography of hamadryas baboons by sequencing a portion of the control region of mtdna in 107 baboons from four saudi arabian populations and combing these data with published data from ... | 2004 | 15315692 |
| cosupplementation with vitamin e and coenzyme q10 reduces circulating markers of inflammation in baboons. | inflammation and oxidative stress are processes that mark early metabolic abnormalities in vascular diseases. | 2004 | 15321805 |
| baboon palm nut harvesters in ancient egypt: new (ancient) evidence, new questions. | it is well documented that hamadryas baboons were used by the ancient egyptians to pick fruits, but it is not well known that these baboons were also used to collect palm nuts. we describe this practice as it is depicted on a painting on a rarely exhibited ancient egyptian artefact. striking similarities with the modern use of pig-tailed macaques as coconut harvesters are described, raising new questions about the demise of the practice in africa and its continuation in south-east asia. | 2009 | 19628946 |
| does relative economic value of food elicit purposeful encounter in the yellow baboons (papio hamadryas cynocephalus) of ruaha national park, tanzania? | in the dry season, baboons traveled purposefully to spatially predictable foods that provided a relatively large number of grams per minute of preparation (e.g., economical foods), but not to predictable foods that merely accounted for a large proportion of feeding time (pochron in int j primatol 22:773-785, 2001). in this paper, i examined the generality of those findings across seasons and applied the same methods to baboons eating a lush-season diet. i hypothesized that baboons should travel ... | 2005 | 15340858 |
| detection by pcr and isolation assays of the anaerobic intestinal spirochete brachyspira aalborgi from the feces of captive nonhuman primates. | the purpose of this study was to investigate the presence of the anaerobic intestinal spirochetes brachyspira aalborgi and brachyspira pilosicoli in the feces of captive nonhuman primates (n = 35) from 19 species housed at the zoological gardens, perth, western australia. both spirochete species are known to infect human beings. dna was extracted from freshly collected feces with a commercially available qiaamp dna stool minikit and subjected to pcr protocols amplifying portions of the 16s rrna ... | 2003 | 12624050 |
| the relative lengths and weights of metacarpals and metatarsals in baboons (papio hamadryas). | the lengths and weights of metacarpals and metatarsals were measured in two collections of baboon skeletons-33 animals, all born and raised in the wild, and 60 animals, nearly all born and raised in captivity. for both length and weight, ratios were constructed for all possible pairings of the five bones in each individual hand and foot. the pattern of results was not identical for the two collections, but substantial sex differences existed in both collections for many of the ratios calculated. ... | 2003 | 12694645 |
| dental microwear in anubis and hybrid baboons (papio hamadryas, sensu lato) living in awash national park, ethiopia. | we describe dental microwear in baboons (papio hamadryas sensu lato) from the anubis-hamadryas hybrid zone of awash national park, ethiopia, outline its variation with sex and age, and attempt to relate the observed microwear pattern to environment and diet. casts of the maxillary second molar of 52 adult and subadult individuals of both sexes were examined with a scanning electron microscope at x 500. digitized micrographs were taken at a consistent location on facet 9, and microwear was record ... | 2004 | 15386258 |
| the use of a hypo-osmotic swelling (hos) test on sperm of the pig (sus scrofa domesticus), emu (dromaius novaehollandiae), asian elephant (elephas maximus), hamadryas baboon (papio hamadryas hamadryas), and central rock rat (zyzomys pedunculatus). | a hypo-osmotic swelling test using talp-hepes medium over a range of 50 to 300 mosm/kg was applied to sperm from domestic and endangered species. maximal responses of curling of the sperm tails were seen over a range of osmolalities for epididymal sperm from the pig (100 mosm/kg), hamadryas baboon (range 50-125 mosm/kg), and central rock rat (range 50-100 mosm/kg), and the ejaculated sperm from the emu (50 mosm/kg) and the asian elephant (range 75-150 mosm/kg). a solution of talp-hepes medium at ... | 2009 | 19734955 |
| primate maternal placental angiography. | in humans, it is known that blood flow is directed to the gravid uterus from two (right and left) pelvic uterine arteries. the extent of supply from the tubo-ovarian anastomosis (joining of the ovarian and uterine arteries) is unknown. the aim of this study was to delineate the arterial blood supply to the placenta via systematic angiography in normal pregnancies in a non-human primate, the baboon (papio hamadryas). | 2010 | 19897240 |
| comparative analysis of muscle architecture in primate arm and forearm. | a comparative study of myological morphology, i.e. muscle mass (mm), muscle fascicle length and muscle physiological cross-sectional area (an indicator of the force capacity of muscles), was conducted in nine primate species: human (homo sapiens), chimpanzee (pan troglodytes), gibbon (hylobates spp.), papio (papio hamadryas), lutong (trachypithecus francoisi), green monkey (chlorocebus aethiops), macaque monkey (macaca spp.), capuchin monkey (cebus albifrons) and squirrel monkey (saimiri sciureu ... | 2010 | 19958344 |
| beta2-toxin of clostridium perfringens in a hamadryas baboon (papio hamadryas) with enteritis. | an 11-yr-old female hamadryas baboon (papio hamadryas) that died with a history of diarrhea and anorexia was submitted for necropsy. major pathologic changes were restricted to the gastrointestinal tract. the small intestinal contents were watery and sanguinous, with a deepening of the red color in the large intestines. the intestinal mucosa was hyperemic. microscopically, lesions consisted of surface epithelial cell necrosis in association with numerous rod-shaped bacteria and high numbers of t ... | 2009 | 20063832 |
| refractive power and biometric properties of the nonhuman primate isolated crystalline lens. | purpose. to characterize the age dependence of shape, refractive power, and refractive index of isolated lenses from nonhuman primates. methods. measurements were performed on ex vivo lenses from cynomolgus monkeys (cyno: n = 120; age, 2.7-14.3 years), rhesus monkeys (n = 61; age, 0.7-13.3 years), and hamadryas baboons (baboon: n = 16; age, 1.7-27.3 years). lens thickness, diameter, and surface curvatures were measured with an optical comparator. lens refractive power was measured with a custom ... | 2010 | 20107174 |
| identification of human specific gene duplications relative to other primates by array cgh and quantitative pcr. | in order to identify human lineage specific (hls) copy number differences (cnds) compared to other primates, we performed pair wise comparisons (human vs. chimpanzee, gorilla and orangutan) by using cdna array comparative genomic hybridization (cgh). a set of 23 genes with hls duplications were identified, as well as other lineage differences in gene copy number specific of chimpanzee, gorilla and orangutan. each species has gained more copies of specific genes rather than losing gene copies. el ... | 2010 | 20153417 |
| de novo sequencing of two new cyclic theta-defensins from baboon (papio hamadryas) leukocytes by matrix-assisted laser desorption/ionization mass spectrometry. | two cyclic theta-defensin peptides were isolated from leukocytes of the hamadryas baboon, papio hamadryas, and purified to homogeneity by gel electrophoresis and reversed-phase high-performance liquid chromatography. both peptides had high in vitro activity against escherichia coli, listeria monocytogenes, methicillin-resistant staphylococcus aureus (mrsa) and candida albicans. here, we report their de novo sequencing by matrix-assisted laser desorption/ionization tandem time-of-flight mass spec ... | 2010 | 20155756 |
| the pattern of the arterial supply of the pancreas in anthropoid apes, catarrhine monkeys and platyrrhine monkeys. | to get the full understanding of the arterial distribution to the pancreas, the analysis of the distribution of the variety of monkey species would be helpful. in this study, we studied the layout of the pancreatic artery in anthropoids (1 gorilla, 3 chimpanzees and 2 white-handed gibbons), in catarrhine monkeys (1 hamadryas baboon, 2 anubid baboons, 10 savannah monkeys) and in platyrrhine monkeys (6 squirrel monkeys). the pancreas of the monkeys was supplied by the arteries originating from the ... | 2009 | 20166548 |
| inflammatory, hemostatic, and clinical changes in a baboon experimental model for heatstroke. | the mortality and neurological morbidity in heatstroke have been attributed to the host's inflammatory and hemostatic responses to heat stress, suggesting that immunomodulation may improve outcome. we postulated that an experimental baboon model of heatstroke will reproduce human responses and clinical outcome to allow testing of new therapeutic strategies. eight anesthetized juvenile baboons (papio hamadryas) were subjected to heat stress in an incubator maintained at 44-47 degrees c until rect ... | 2005 | 15475604 |
| flow cytometric sorting of non-human primate sperm nuclei. | pre-determination of the sex of offspring has implications for management and conservation of captive wildlife species, particularly those with single sex-dominated social structures. our goal is to adapt flow cytometry technology to sort spermatozoa of non-human primate species for use with assisted reproductive technologies. the objectives of this study were to: (i) determine the difference in dna content between x- and y-bearing spermatozoa (ii) sort sperm nuclei into x- and y-enriched sample ... | 2005 | 15589288 |
| trisomy of chromosome 18 in the baboon (papio hamadryas anubis). | trisomy 18 is usually a lethal chromosomal abnormality and is the second most common autosomal trisomy in humans, with an incidence of 1:8000 live births. it is commonly associated with abnormalities of the lower and upper extremities, having the frequency of 95% and 65%, respectively. a newborn female olive baboon (papio hamadryas anubis) was diagnosed with intrauterine growth retardation and severe arthrogryposis-like congenital joint deformities. cytogenetic analysis including g-banding and f ... | 2006 | 16276093 |
| thermal constraints on activity scheduling and habitat choice in baboons. | the importance of thermoregulation as a constraint on behavior has received comparatively little attention in relation to other ecological factors. despite this, a number of studies suggested that high temperature may represent an important ecological constraint. this paper examines the impact of temperature on activity scheduling in a troop of chacma baboons (papio hamadryas ursinus) at de hoop nature reserve, south africa. once the daily, seasonal, and individual effects were controlled for, t ... | 2006 | 16323181 |
| why be diurnal? or, why not be cathemeral? | as a behavioural strategy, cathemerality is thought to confer considerable advantages by allowing animals to extend activity flexibly into either the diurnal or nocturnal phase in response to the prevailing ecological conditions. factors such as temperature, access to food sources and minimising the risk of predation are all thought to be important in promoting cathemerality, although previous studies have produced inconsistent results. this paper adopts a different approach by first asking whet ... | 2006 | 16415578 |
| design, synthesis, and structure-affinity relationships of regioisomeric n-benzyl alkyl ether piperazine derivatives as sigma-1 receptor ligands. | a series of n-(benzofuran-2-ylmethyl)-n'-benzylpiperazines bearing alkyl or fluoroalkyl aryl ethers were synthesized and evaluated at various central nervous system receptors. examination of in vitro sigma1 {[3h]+-pentazocine} and sigma2 ([3h]dtg) receptor binding profiles of piperazines 11-13 and 25-36 revealed several highly potent and sigma1 selective ligands, notably, n-(benzofuran-2-ylmethyl)-n'-(4'-methoxybenzyl)piperazine (13, ki=2.7 nm, sigma2/sigma1=38) and n-(benzofuran-2-ylmethyl)-n'- ... | 2010 | 20662542 |
| patterns of gastro-intestinal parasites and commensals as an index of population and ecosystem health: the case of sympatric western chimpanzees (pan troglodytes verus) and guinea baboons (papio hamadryas papio) at fongoli, senegal. | the exponential decline of great apes over the past 50 years has resulted in an urgent need for data to inform population viability assessment and conservation strategies. health monitoring of remaining ape populations is an important component of this process. in support of this effort, we examined endoparasitic and commensal prevalence and richness as proxies of population health for western chimpanzees (pan troglodytes verus) and sympatric guinea baboons (papio hamadryas papio) at fongoli, se ... | 2011 | 20853397 |
| eight week exposure to a high sugar high fat diet results in adiposity gain and alterations in metabolic biomarkers in baboons (papio hamadryas sp.). | baboons (papio hamadryas sp.) develop features of the cardiometabolic syndrome and represent a clinically-relevant animal model in which to study the aetiology of the disorder. to further evaluate the baboon as a model for the study of the cardiometabolic syndrome, we developed a high sugar high fat diet and hypothesized that it could be used to induce adiposity gain and affect associated circulating biomarkers. | 2010 | 21034486 |
| [data on intestinal parasites of lower monkeys in the adler apery]. | under captive conditions, a parasite fauna connected with the changes in ecological conditions, feeding, and mode of life is usually formed in monkeys. species composition of the intestinal parasites has been investigated in six species of the monkeys (macaca mulatta, m. fascicularis, m. nemestrina, ceropithecus aethiops, papio hamadryas, and p. anubis), which were born in the adler apery and live there for a long time. a comparison with similar investigations carried out in the sukhumi apery, w ... | 2010 | 21061593 |
| chemical characterization of oligosaccharides in the milk of six species of new and old world monkeys. | human and great ape milks contain a diverse array of milk oligosaccharides, but little is known about the milk oligosaccharides of other primates, and how they differ among taxa. neutral and acidic oligosaccharides were isolated from the milk of three species of old world or catarrhine monkeys (cercopithecidae: rhesus macaque (macaca mulatta), toque macaque (macaca sinica) and hamadryas baboon (papio hamadryas)) and three of new world or platyrrhine monkeys (cebidae: tufted capuchin (cebus apell ... | 2010 | 21127965 |
| a naturally occurring fatal case of herpesvirus papio 2 pneumonia in an infant baboon (papio hamadryas anubis). | here we describe the unusual finding of herpesvirus pneumonia in a 7-d-old infant baboon (papio hamadryas anubis). this animal had been separated from its dam the morning of its birth and was being hand-reared for inclusion in a specific pathogen-free colony. the baboon was presented for anorexia and depression of 2 d duration. physical examination revealed a slightly decreased body temperature, lethargy, and dyspnea. the baboon was placed on a warm-water blanket and was given amoxicillin-clavul ... | 2006 | 16539338 |
| genetic evidence for female-biased dispersal and gene flow in a polygynous primate. | many models of sex-biased dispersal predict that the direction of sex-bias depends upon a species' mating system. in agreement with this, almost all polygynous mammals show male-biased dispersal whereas largely monogamous birds show female-biased dispersal (fbd). the hamadryas baboon (papio hamadryas hamadryas) is polygynous and so dispersal is predicted to be male biased, as is found in all other baboon subspecies, but there are conflicting field data showing both female and male dispersal. usi ... | 2006 | 16615216 |
| a second-generation genetic linkage map of the baboon (papio hamadryas) genome. | construction of genetic linkage maps for nonhuman primate species provides information and tools that are useful for comparative analysis of chromosome structure and evolution and facilitates comparative analysis of meiotic recombination mechanisms. most importantly, nonhuman primate genome linkage maps provide the means to conduct whole genome linkage screens for localization and identification of quantitative trait loci that influence phenotypic variation in primate models of common complex hu ... | 2006 | 16697552 |
| metabolic adjustments to moderate maternal nutrient restriction. | reduced food availability in pregnancy influences fetal growth, obstetric outcomes and offspring health in both developing and developed countries. the objective of the present study was to determine responses to moderate global maternal nutrient restriction (mnr) during pregnancy in baboons (papio hamadryas) - an established non-human primate model for pregnancy-related research. starting at 30 d gestation (dg), twelve pregnant baboons received 70 % of food (mnr group) consumed by twenty ad lib ... | 2007 | 17391566 |
| primate lens capsule elasticity assessed using atomic force microscopy. | the purpose of this project is to measure the elasticity of the human and non-human primate lens capsule at the microscopic scale using atomic force microscopy (afm). elasticity measurements were performed using afm on the excised anterior lens capsule from 9 cynomolgus monkey (5.9-8.0 years), 8 hamadryas baboon (2.8-10.1 years), and 18 human lenses (33-79 years). anterior capsule specimens were obtained by performing a 5 mm continuous curvilinear capsulorhexis and collecting the resulting disk ... | 2011 | 21420953 |
| use of palm trees as a sleeping site for hamadryas baboons (papio hamadryas hamadryas) in ethiopia. | hamadryas baboons sleep on cliffs throughout their range, and this can be attributed to the safety cliffs provide against predators in the absence of tall trees. in this paper, we report the first documented occurrence of hamadryas baboons sleeping in doum palm trees rather than on cliffs. data derive from a study of hamadryas baboons at the filoha site in lowland ethiopia. during all-day follows, data were collected on travel patterns, band activity, and location. variation in the baboons' home ... | 2008 | 17701992 |
| behavioral variation and reproductive success of male baboons (papio anubis x papio hamadryas) in a hybrid social group. | we take advantage of an array of hybrid baboons (papio anubis x papio hamadryas) living in the same social group to explore the causes and consequences of different male mating strategies. male hamadryas hold one-male units and exhibit a sustained, intense interest in adult females, regardless of the latter's reproductive state. anubis baboons, by contrast, live in multi-male, multi-female groups where males compete for females only when the latter are estrous. these two taxa interbreed to form ... | 2008 | 17724672 |
| tumor necrosis factor α induces a model of preeclampsia in pregnant baboons (papio hamadryas). | preeclampsia is a common disease of pregnancy characterised by maternal hypertension and proteinuria. abnormal placentation in early pregnancy and abnormal cytokine and anti-angiogenic factor expression are thought to contribute to the clinical syndrome of endothelial dysfunction evident in the second half of gestation. the mechanisms underlying both the placental pathology and its translation to the maternal clinical syndrome are not fully understood. a model of preeclampsia manifest by clinica ... | 2011 | 21737300 |
| high-resolution imaging of the large non-human primate brain using micropet: a feasibility study. | the neuroanatomy and physiology of the baboon brain closely resembles that of the human brain and is well suited for evaluating promising new radioligands in non-human primates by pet and spect prior to their use in humans. these studies are commonly performed on clinical scanners with 5 mm spatial resolution at best, resulting in sub-optimal images for quantitative analysis. this study assessed the feasibility of using a micropet animal scanner to image the brains of large non-human primates, i ... | 2007 | 17975287 |