| phenotypic responses of hatchlings to constant versus fluctuating incubation temperatures in the multi-banded krait, bungarus multicintus (elapidae). | most studies on egg incubation in reptiles have relied on constant temperature incubation in the laboratory rather than on simulations of thermal regimes in natural nests. the thermal effects on embryos in constant-temperature studies often do not realistically reflect what occurs in nature. recent studies have increasingly recognized the importance of simulating natural nest temperatures rather than applying constant-temperature regimes. we incubated bungarus multicintus eggs under three consta ... | 2007 | 17867836 |
| cathelicidin-bf suppresses intestinal inflammation by inhibiting the nuclear factor-κb signaling pathway and enhancing the phagocytosis of immune cells via stat-1 in weanling piglets. | the severity of intestinal inflammation in mammals can be profoundly impacted by weaning stress. cathelicidins protect intestinal homeostasis by not only directly killing bacteria but also immune regulators. here, we investigated the effects of cathelicidin-bf (c-bf) derived from the snake venoms of bungarus fasciatus on weaning stress and intestinal inflammation and examined the mechanisms by which c-bf modulates intestinal immune responses in weanling piglets. we found that c-bf treatment sign ... | 2015 | 26044347 |
| capillary electrophoresis versus differential scanning calorimetry for the analysis of free enzyme versus enzyme-ligand complexes: in the search of the ligand-free status of cholinesterases. | cholinesterases (ches) are highly efficient biocatalysts whose active site is buried in a deep, narrow gorge. the talent of ce to discover inhibitors in the gorge of highly purified preparations has fairly altered the meaning of a che ligand-free status. to attempt at a description of this one, we investigated the stability of bungarus fasciatus acetylcholinesterase (ache), alone or complexed with different inhibitors. determination of mid-transition temperature for thermal denaturation, using d ... | 2006 | 16342323 |
| kinetics study of bungarus fasciatus venom acetylcholinesterase immobilised on a langmuir-blodgett proteo-glycolipidic bilayer. | this study deals with the kinetics properties of an enzyme immobilised in a defined orientation in a biomimetic environment. for this purpose, acetylcholinesterase (ache) was captured at the surface of a nanostructured proteo-glycolipidic langmuir-blodgett film through specific recognition by a noninhibitor monoclonal antibody (igg) inserted in a neoglycolipid bilayer. modelling of this molecular assembly provided a plausible interpretation of the functional orientation of the enzyme. the ache a ... | 2005 | 15651043 |
| alpha-bungarotoxin binding to acetylcholine receptor membranes studied by low angle x-ray diffraction. | the nicotinic acetylcholine receptor (nachr) carries two binding sites for snake venom neurotoxins. alpha-bungarotoxin from the southeast asian banded krait, bungarus multicinctus, is a long neurotoxin which competitively blocks the nachr at the acetylcholine binding sites in a relatively irreversible manner. low angle x-ray diffraction was used to generate electron density profile structures at 14-a resolution for torpedo californica nachr membranes in the absence and presence of alpha-bungarot ... | 2003 | 12885641 |
| cathelicidin-bf, a novel antimicrobial peptide from bungarus fasciatus, attenuates disease in a dextran sulfate sodium model of colitis. | antimicrobial peptides are molecules of innate immunity. cathelicidin-bf is the first cathelicidin peptide found in reptiles. however, the immunoregulatory and epithelial barrier protective properties of c-bf have not been reported. inflammatory bowel diseases, including ulcerative colitis and crohn's disease, can lead to colon cancer, the third most common malignant tumor. the objective is to develop the new found cathelicidin-bf as a therapeutic to patients of ulcerative colitis. the morpholog ... | 2015 | 25807257 |
| ultrastructure of the tongue and anterior process of the sublingual plica in four species of venomous snakes. | the general histology and ultrastructure of the tongue and anterior process of the sublingual plica of four taiwanese venomous snakes, the chinese cobra (naja naja atra), banded krait (bungarus multicinctus), taiwan habu (trimeresurus mucrosquamatus), and bamboo snake (trimeresurus stejnegeri stejnegeri) are described. the tongue fork exhibits a mid-dorsal invagination that broadens gradually toward its base. no mid-ventral invagination is observed. the epithelial cells on both dorsal and ventra ... | 1991 | 29865528 |