| trypanosoma lewisi: antibody classes which mediate precipitation, agglutination, and the inhibition of reproduction. | | 1982 | 6799316 |
| the effects of pantothenic acid, pantoyltaurine, salicylate and related compounds on the in vitro and in vivo growth of trypanosoma lewisi. | | 1968 | 5710274 |
| trypanosoma lewisi: avidity and adsorbability of ablastin, the rat antibody inhibiting parasite reproduction. | | 1980 | 7000542 |
| comparison of mitochondrial enzymes between young and adult forms of trypanosoma lewisi. | | 1968 | 5719060 |
| [parasite-host relationship specificity in rat trypanosomiasis]. | | 1981 | 7015099 |
| [on the host specificity of trypanosoma lewisi infection]. | | 1968 | 5719578 |
| rheumatoid factor-like immunoglobulin m protects previously uninfected rat pups and dams from trypanosoma lewisi. | the serum of lactating rats that have never been infected with the protozoan parasite trypanosoma lewisi contains a rheumatoid factor-like immunoglobulin m (igm). this igm amplifies a specific immunoglobulin g (igg) response to the parasite and accounts for the unusual resistance of previously uninfected lactating rats and their suckling pups to infection with t. lewisi. a similar rheumatoid factor-like igm, which is induced late in the usual course of infection with t. lewisi in nonlactating ra ... | 1981 | 7025211 |
| carbohydrate transport in trypanosoma lewisi. | | 1969 | 5778271 |
| trypanosoma lewisi: enhanced resistance in naive lactating rats and their suckling pups. | | 1982 | 7037439 |
| the parasites obtained and bacteria isolated from house rats (rattus rattus linnaeus, 1758) caught in human habitations in ibadan, nigeria. | a total of 169 house rats were killed in different households distributed within five localities of ibadan. a wide range of parasites were encountered. the flea, ceratophylus fasciatus was the commonest ectoparasite found. trichostrongylus columbriformis eggs were the commonest nematode and hymenolepis diminuta the only cestode. escherichia coli was the commonest bacterium found. the incidence of helminthiasis, especially h. diminuta, was generally high among rats trapped in the villages and the ... | 1981 | 7037672 |
| oxygen uptake by trypanosoma lewisi-complex cells. ii. r and l isolates compared. | | 1966 | 5940094 |
| oxygen uptake by trypanosoma lewisi complex cells. 3. c isolate. | | 1966 | 5943918 |
| immunoconglutinin and antibody against fibrinogen products in hemolytic anemia and nephritis resulting from infection with a haemobartonella-like agent. | an agent morphologically similar to haemobartonella muris was isolated from the blood of rats infected with a strain of trypanosoma lewisi kept at this department. it caused acute hemolytic anemia, splenomegaly, glomerulonephritis, and death within 5 to 8 days in mature sprague-dawley rats. the disease was less severe in weanling rats which usually recovered within 3 to 4 wk. the anemia was accompanied by phagocytosis of erythrocytes by monocytes of the spleen and bone marrow, by high titers of ... | 1981 | 7264835 |
| trans-sialidase and sialidase activities discriminate between morphologically indistinguishable trypanosomatids. | the expression of trans-sialidase and sialidase activities in the kinetoplastid protozoa was explored as a potential marker to discriminate between the morphologically indistinguishable flagellates isolated from human, insects and vertebrate reservoir hosts. by virtue of the differences observed in the ratios of these enzyme activities, a collection of 52 species and strains comprising the major taxa of these parasites could be separated into four expression types. type-i parasites express compa ... | 1994 | 7925453 |
| an unusual morphological type of trypanosoma (herpetosoma) lewisi (kent, 1880) detected in the blood of rattus norvegicus in india. | an unusual morphological type of trypanosoma (herpetosoma) lewisi (kent, 1880) which was detected in rattus norvegicus in india is reported in the present study. this type is different from known types of t. lewisi in that the kinetoplast is at a greater distance from the posterior end (p-k) than the usual type. the total length, including the free flagellum, is 35.3-39.3 microns and p-k is 11.9-15.0 as against total length of 21 to 36.5 microns in the normal form. | 1993 | 8014434 |
| identification of membrane-associated proteins in trypanosoma brucei encoding an internal, earlraee amino acid repeat. | differential screening of expression libraries with nonimmune and day 4-6 immune serum from naive rats infected with the protozoan trypanosoma lewisi was used to identify potential cell surface protein coding genes. several t. lewisi cdnas that resulted were partially characterized and used to clone the homologues from trypanosoma brucei. the nucleotide sequence of the cdnas encoding the tb-29 genes of the parasitic protozoan t. brucei obtained by this method (3557 nucleotides for tb-291 and 872 ... | 1994 | 8132566 |
| natural babesia infection sought in black and norway rats trapped in five egyptian governorates. | babesiosis is a protozoal disease caused by members of the genus babesia transmitted by the ixodid ticks. it is a parasite of various mammalian hosts as bovine (b. bovis), equine (b. equi), rodent (b. microti), canine (b. canis) and others. human cases of babesiosis have been reported from several countries including egypt. it is now well established that man may become infected (fulminating or subclinical) with several species of babesia without prior splenectomy. in this paper, a total of 398 ... | 1993 | 8376851 |
| [some data on zooflagellate ribosomes]. | | 1971 | 4942544 |
| [prevalence of protozoa infections in synanthropic rodents in valdivia city, chile]. | in order to determine the prevalence of infection by blood and intestinal protozoa in 57 synanthropic rodents from valdivia city, a study was carried out in the period march-september 1986. the group of rodents studied was constituted by 31 mus musculus, 19 rattus rattus and 7 oryzomys longicaudattus, being 42 males and 15 females. diagnostic forms of protozoa were found in 70.2% of the investigated animals. the presence of five species of enteroprotozoa and one species of hemoflagelate was dete ... | 1995 | 8762669 |
| homologues of the 24-kda flagellar ca(2+)-binding protein gene of trypanosoma cruzi are present in other members of the trypanosomatidae family. | a full-length cdna encoding the 24-kda flagellar ca(2+)-binding protein (fcabp) of the dm28c clone of trypanosoma cruzi was cloned and characterized. comparison of the deduced amino acid sequence with those of the fcabps of other t. cruzi strains revealed greater than 97% sequence conservation. fcabp-like genes are found in trypanosoma conorhini, trypanosoma freitasi, trypanosoma lewisi, herpetomonas megaseliae, leptomonas seymouri, and phytomonas serpens, but not in crithidia deanei, leishmania ... | 1997 | 9225770 |
| increasing of toxoplasma gondii (coccidia, sarcocystidae) infections by trypanosoma lewisi (kinetoplastida, trypanosomatidae) in white rats. | to demonstrate that t. lewisi infection increases t. gondii multiplication in white rats, groups of five wistar or sprague dawley rats were inoculated with 10(6) t. lewisi trypomastigotes and four or seven days later infected with toxoplasma tachyzoites. host survival time was monitored, and the presence of t. gondii was confirmed in all dead rats by studying peritoneal exudate smears and lung tissue sections stained with haematoxylin-eosin. the presence of toxoplasma cysts or antibodies was che ... | 1997 | 9458990 |
| effect of trypanosoma lewisi (kinetoplastida: trypanosomatidae) on the infection of white rats with toxoplasma gondii (eucoccidia: sarcocystidae) oocysts. | white rats were inoculated with 10(6) trypomastigotes of trypanosoma lewisi, simultaneously or two days before and after inoculation with 10(5) oocysts of t. gondii. a greater number of cysts was found in the brain of the animals having concomitant inoculations, as compared with rats inoculated with either one of the two parasites. an apparent immunosuppressive effect is likely. since both organisms can be found in rats, it is possible that infections with t. lewisi, could make this rodent anoth ... | 1998 | 10751936 |
| schistosoma japonicum in the black rat, rattus rattus mindanensis, from leyte, philippines in relation to oncomelania snail colonies with reference to other endoparasites. | this study examined the prevalence of schistosoma japonicum infections in field rats, rattus rattus mindanensis, according to different trapping locations. between october 1995 and january 1996, traps were set in the municipality of palo, leyte, philippines to determine the correlation of rats infected with schistosomiasis to the proximity of the intermediate snail host, oncomelania hupensis quadrasi, colonies. of the 22 rats that were caught within a snail colony, 21 (95.5%) were positive for s ... | 1999 | 10774707 |
| [comparative studies of the desoxythymidylate synthesis in plasmodium chabaudi, trypanosoma gambiense and trypanosoma lewisi]. | | 1970 | 5275559 |
| lipopolysaccharide hyperreactivity of animals infected with trypanosoma lewisi or trypanosoma musculi. | rats and mice infected with trypanosoma lewisi and trypanosoma musculi, respectively, showed hyperreactivity to lipopolysaccharide (lps) from gram-negative bacteria. fatal shock could be precipitated with a dose of lps 100 to 1,000 times less in infected compared with noninfected animals. in trypanosome-infected rats and mice, extensive liver damage was evident after lps challenge. these animals showed a pronounced hypoglycemia, marked elevation of blood aspartate transaminase level, and diffuse ... | 1984 | 6500700 |
| pcr identification of trypanosoma lewisi, a common parasite of laboratory rats. | trypanosoma (herpetosoma) lewisi is a trypanosome of the sub-genus herpetosoma (stercoraria section), parasite of rats (rattus rattus and rattus norvegicus) transmitted by fleas. t. lewisi has a stringent species specificity and cannot grow in other rodents such as mice. rats are infected principally by oral route, through contamination by flea faeces or ingestion of fleas. trypanosoma lewisi infections in rat colonies can interfere with research protocols and fleas of wild rats are often the so ... | 2002 | 12234387 |
| comparative positions of kinetoplasts in trypanosoma musculi and trypanosoma lewisi during development in vitro. | the development of trypanosoma musculi and trypanosoma lewisi were studied in vitro in the presence of adherent splenic cells. both parasites developed only when attached by their flagellar tips to adherent splenic cells. during the proliferation of t. musculi, the kinetoplast migrated towards the nucleus, and once in the vicinity of the nucleus, the nuclear division was triggered. the kinetoplast of t. lewisi did not migrate towards the nucleus, but remained at its original location. the nucleu ... | 2002 | 12269904 |
| some field and laboratory studies on rattus rattus subspecies and rattus norvegicus in two egyptian governorates of different ecological characters. | both damietta and qualyobia governorates were examined for the seasonal activities of rattus species and subspecies and their natural infection with trypanosoma lewisi. the common domestic rodents identified were rattus r. alexandrinus, r. r. frugivorus and rattus norvegicus. they were common all the year round except in winter for r. norvegicus in damietta. gravid females of the three rodent species, were identified in damietta in summer, in addition to autumn for r. norvegicus only. in qualyob ... | 2002 | 12512813 |
| properties of ablastin--a factor in the serum of rats infected with trypanosoma lewisi which inhibits the parasites' division. | the present study investigated the nature of ablastin, a factor present in the serum of rats infected with trypanosoma lewisi and which inhibits the parasites' division. ablastin was unstable to dialysis at ph 1x8, was not adsorbed from serum by trypanosomes and could not be induced in vivo by means other than a natural infection. attempts to purify ablastin from serum by conventional chromatographic techniques were unsuccessful. removal of over 90% of the immunoglobulins from ablastinic serum d ... | 1982 | 6753814 |
| incidence of trypanosoma lewisi and hepatozoon muris in the norway rat. | | 1952 | 12981595 |
| effect of sodium salicylate treatment on antibody titers in rats infected with trypanosoma lewisi. | | 1953 | 13120947 |
| the oxidative metabolism of trypanosoma lewisi from salicylate treated infected white rats. | | 1954 | 13202012 |
| observations on trypanosoma lewisi and grahamella sp. in the blood of rats from the hamakua district, island of hawaii. | | 1954 | 13202016 |
| the effect of salicylate treatment on plasma proteins in rats infected with trypanosoma lewisi. | | 1956 | 13305593 |
| effects of hypoxia on rats infected by trypanosoma lewisi. | | 1956 | 13319771 |
| immunization against trypanosoma lewisi in rats by injections of metabolic products. | | 1957 | 13401232 |
| growth of trypanosoma lewisi in the heterologous mouse host. | | 1958 | 13501231 |
| the ingestion of particulate fat from the blood by trypanosoma lewisi and trypanosoma equiperdum. | | 1957 | 13504862 |
| some considerations relative to the nature of immunity in trypanosoma lewisi infections. | | 1958 | 13539705 |
| the oxygen uptake of trypanosoma lewisi and trypanosoma equiperdum, with especial reference to oxygen consumption in the presence of amino-acids. | | 1958 | 13566862 |
| the effect of some metabolic inhibitors on the oxygen uptake of trypanosoma lewisi and trypanosoma equiperdium. | | 1958 | 13566863 |
| electrophoretic and ultracentrifugal studies of antibodies to trypanosoma lewisi. | | 1959 | 13665055 |
| effect of salicylates and related compounds on ablastic response in rats infected with trypanosoma lewisi. i. isomers of salicylic acid. | | 1961 | 13688445 |
| effect of cortisone and x-irradiation on the course of trypanosoma lewisi infection in the rat. | | 1961 | 13713517 |
| a semi-automated microassay method for the measurement of ablastin, a division inhibitory antibody. | division of trypanosoma lewisi in the rat is terminated by ablastin, a factor(s) in the serum of rats acquired during infection which is believed to be specific antibody. in this study a semi-automated microassay technique for the measurement of ablastin is described. the system involved the use of [3h]tdr as a marker for trypanosome division and a multiple-well cell harvester to harvest trypanosomes from wells of microtitre plates. the method is versatile, quantitative and easy to perform, perm ... | 1982 | 6759583 |
| [proteolytic activity of 4 protozoan species]. | | 1981 | 6786380 |
| isolation and characterization of pellicular membranes from trypanosoma lewisi bloodstream forms. | | 1980 | 6993644 |
| depression of parasitemia in trypanosoma lewisi infection of rats injected with 6-mercaptopurine. | | 1962 | 13863072 |
| effect of salicylates and related compounds on ablastic response in rats infected with trypanosoma lewisi. ii. dihydroxybenzoic acids; antagonisms. | | 1961 | 13866324 |
| in vitro studies of ablastin, the reproduction-inhibiting antibody to trypanosoma lewisi. | | 1962 | 13882937 |
| incidence of trypanosoma lewisi in puerto rican bats. | | 1962 | 13894373 |
| changes in lactic dehydrogenase levels of trypanosoma lewisi associated with appearance of ablastic immunity. | | 1964 | 14213222 |
| ultrastructure of trypanosoma lewisi. | | 1964 | 14244808 |
| synthesis of unsaturated fatty acids in the slime mold physarum polycephalum and the zooflagellates leishmania tarentolae, trypanosoma lewisi, and crithidia sp.: a comparative study. | | 1965 | 14280472 |
| effect of x-irradiation on trypanosoma lewisi infection in the rat. | | 1965 | 14281214 |
| oxygen uptake by trypanosoma lewisi complex cells--i. l isolate. | | 1965 | 14314982 |
| effect of bacterial endotoxin on trypanosoma lewisi infections in rats. | | 1965 | 14339383 |
| the phospholipases of pathogenic and non-pathogenic trypanosoma species. | four species of trypanosome were examined for phospholipase activities using 1-[3h]palmitoyl-2-acyl-sn-glycero-3-phosphocholine and 1-acyl-2[14c]linoleoyl-sn-glycero-3-phosphocholine as substrates. the major activity in each species is a phospholipase a1 (ec 3.1.1.32) which does not require calcium. the most effective of the detergents tested for activation of the enzyme from each species, and the ph optima, are as follows: trypanosoma brucei, 0.125% triton x-100 at ph 6.0-8.5; t. congolense, 0. ... | 1981 | 7012615 |
| observations on changes in trypanosoma lewisi after growth in calorically restricted and in normal mice. | | 1959 | 14417031 |
| a study of cytoplasmic inclusions in trypanosoma lewisi and their relationship to the formation of antibody. | | 1959 | 14429094 |
| persistent infection of mongolian jirds with a non-pathogenic trypanosome, trypanosoma (herpetosoma) grosi. | non-pathogenic trypanosomes of the subgenus herpetosoma are normally host specific, and laboratory models include trypanosoma lewisi in rats and trypanosoma musculi in mice. two isolates of trypanosoma grosi, originating from apodemus agrarius and apodemus peninsulae, grew well in mongolian jirds, meriones unguiculatus, after intraperitoneal inoculation of 2 x 10(5) or a minimum 500 bloodstream forms. the course of t. grosi infection in jirds resembled t. musculi infection in mice, rather than t ... | 2003 | 14636022 |
| on the reciprocal interference between the growth of yoshida sarcoma and that of trypanosoma lewisi. | | 1950 | 14802575 |
| [incidence of trypanosoma lewisi, sarcocystis muris, species of spirochaeta, and larvae of microfilaria in the rats of panama city and its suburbs]. | | 1951 | 14858447 |
| antagonism of spirillum minus infection in rats towards trypanosoma lewisi and t. equinum. | | 1951 | 14863953 |
| studies on the metabolism of the protozoa. i. metabolism of the parasitic flagellate, trypanosoma lewisi. | | 1951 | 14886348 |
| concerning salicylate inhibition of ablastic activity in trypanosoma lewisi infection. | | 1951 | 14908771 |
| phylogeny, taxonomy and grouping of trypanosoma rangeli isolates from man, triatomines and sylvatic mammals from widespread geographical origin based on ssu and its ribosomal sequences. | phylogenetic relationships among trypanosoma rangeli isolates from man, wild mammals and triatomine bugs from widespread geographical origin were inferred by comparison of the small subunit of ribosomal gene sequences. the phylogenetic trees indicated that the subgenus herpetosoma is polyphyletic and strongly supported division of this group into two monophyletic lineages, one made up of t. rangeli, t. rangeli-like and allied species and other consisting of t. lewisi and related taxa. based on p ... | 2004 | 15552400 |
| the depressed response of spleen cells from rats infected by trypanosoma lewisi in producing a secondary response in vitro to sheep erythrocytes and the ability of soluble products of the trypanosome to induce this depression. | the non-pathogenic trypanosoma lewisi depresses the ability of infected rat spleen cells to respond immunologically to sheep erythrocytes. a study was made to determine whether the parasite would produce this same phenomenon in vitro in marbrook culture vessels with erythrocyte-primed spleen cells from normal rats; the antibody response of the spleen cells was measured by the plaque-forming cell assay. soluble factors from 1 x 10(7) t. lewisi depress the ability of primed cells to form a seconda ... | 1981 | 7019056 |
| the trypanosoma lewisi immunofluorescence test: a new simple technique for simultaneous determination of total antinuclear antibodies and the detection of antibodies to double-stranded dna. | an indirect immunofluorescence technique was developed for the detection of antibodies to dsdna and the simultaneous assessment of antinuclear antibodies 'in toto' (ana). this assay was based upon the use as substrate of smears of peripheral blood derived from rats infected with trypanosoma lewisi. t. lewisi possesses a giant kinetoplast posteriorly to the nucleus. enzyme digestion and absorption experiments provided strong evidence that t. lewisi kinetoplast contains dsdna uncontaminated by oth ... | 1982 | 7035570 |
| a study of the interaction of host and parasite: a reaction product in infections with trypanosoma lewisi which inhibits the reproduction of the trypanosomes. | | 1924 | 16576770 |
| two identical symmetrical regions in the minicircle structure of trypanosoma lewisi kinetoplast dna. | two minicircles of trypanosoma lewisi kinetoplast dna, linearized by different restriction enzymes, have been cloned in m13 derivative vectors. their nucleotide sequences share a dna fragment which accounts for 10% of the minicircle total length. this highly conserved region (constant region) is present twice within the same minicircle in a direct orientation and in an almost symmetrical location. comparison of the t. lewisi constant region with those of t. brucei and t. equiperdum shows identic ... | 1984 | 6096711 |
| trypanostatic activity of rat igg purified from the surface coat of trypanosoma lewisi. | host igg is a component of the surface coat of trypanosoma lewisi; it is specifically acquired during infection in the rat, concomitant with a rise in titer of trypanostatic (ablastic) activity of host serum. host igg was eluted from trypomastigotes at 7 to 9 days postinfection with a high salt-low ph buffer. surface coats and trypanosome ultrastructure were not notably altered by the elution procedure, as determined by electron microscopy. rat igg was removed and purified from the trypanosome e ... | 1982 | 6182278 |
| the inhibition of nucleic acid and protein synthesis in trypanosoma lewisi by the antibody ablastin. | | 1960 | 16590665 |
| molecular cloning of the "minor" component of the kinetoplast dna of trypanosoma lewisi. | kinetoplast dna was cloned in the pbr322 plasmid using the bamhi site. in situ hybridization of iodinated recombinant dna showed hybridization grains only in the kinetoplast region. the recombinant dna was analyzed with restriction enzymes and its base ratio was determined by analytical cscl density gradient. | 1980 | 6257401 |
| basis of the specificity of rodent trypanosomes for their natural hosts. | the strong natural insusceptibility of mice to infection with the rat-specific trypanosoma lewisi was investigated in a variety of mouse strains. parasite elimination by all strains was similar involving a lag phase of about 7 h of constant parasitemia followed by rapid clearance (half-times of 55 and 130 min in different strains). in vitro cultures were utilized to determine whether mouse cells and serum were inherently deficient in supporting t. lewisi or, alternatively, toxic for the parasite ... | 1981 | 6268542 |
| [trypanosomatidae of public health importance occurring in wild and synanthropic animals of rural venezuela]. | chagas disease and leishmaniasis are important public health problems due to their high frequency and broad distribution in latin america. understanding of the roles of reservoir animals is crucial for a global assessment of the epidemiology of these diseases. | 2006 | 16929902 |
| rat liver glucose-6-phosphate dehydrogenase isozymes: influence of infection with trypanosoma. | glucose-6-phosphate dehydrogenase (g6pd) changes were studied in livers of rats inoculated with trypanosoma lewisi, trypanosoma rhodesiense, trypanosoma congolense and trypanosoma brucei. marked increases in g6pd were directly related to the degree of parasitemia. no essential differences in g6pd levels were seen in animals inoculated with physiological saline when compared with uninoculated controls. elevation of g6pd was observed only from day 10 to 20 in rats inoculated with t. lewisi. after ... | 1983 | 6349921 |
| trypanosoma cruzi oleate desaturase: molecular characterization and comparative analysis in other trypanosomatids. | trypanosoma cruzi lipids contain a high content of unsaturated fatty acids, primarily oleic acid (c18:1) and linoleic acid (c18:2). previous data suggest that this parasite is able to convert oleic acid into linoleic acid; humans are not able to do this. presently, we show that t. cruzi has a gene with high similarity to the delta12 (omega6)-oleate desaturase from plants. northern blot analysis of the oleate desaturase gene from t. cruzi (od(tc)) indicated that this gene is transcribed in epimas ... | 2006 | 17152952 |
| infection by trypanosomes in marsupials and rodents associated with human dwellings in ecuador. | small mammals trapped in domestic and peridomestic environments of rural ecuador were screened for trypanosome infection by direct microscopy and hemoculture. identification of species of trypanosomes was then performed by morphological characteristics and by polymerase chain reaction (pcr) assays. of 194 animals collected, 15 were positive for infection (7.73%). eight (4.12%) were infected with trypanosoma cruzi (1 of 33 didelphis marsupialis; 7 of 61 rattus rattus). eleven r. rattus (18.03%) h ... | 2006 | 17304802 |
| the glycoproteins of the complex surface coat of trypanosoma lewisi. | blood stream forms of trypanosoma lewisi from rats previously infected were labelled in vitro by galactose-oxidase oxidation followed by nab3h4 reduction and subjected to 7.5% sds-polyacrylamide gel analysis, by this procedure 8 bands were detected on sds polyacrylamide gel electrophoresis. we conclude that surface composition of trypanosoma lewisi resulted more complex than that of trypanosoma so far studied, suggesting a possible relation with induced immunity and reduced ability of the parasi ... | 1983 | 6354473 |
| alpha 2 macroglobulin activity in rats infected with typanosoma lewisi and treated with cyclophosphamide and its effect on the malignancy of the disease. | trypanosoma lewisi is a common, flagellated parasite of the rat. our previous study showed that rabbits injected with serum collected from rats infected with trypanosoma lewisi and treated with cyclophosphamide (cyi) produced high levels of antibodies against a new protein in the cyi rat serum. | 2007 | 17722867 |
| isolation of protective antigens from trypanosoma lewisi by using trypanostatic (ablastic) immunoglobulin g from the surface coat. | antigens were purified from extracts of trypanosoma lewisi on immunoadsorbent columns of trypanostatic immunoglobulin g eluted from parasite surface coats at 8 days postinfection. eight absorbed proteins, with molecular weights between 15,000 and 70,000, were identified. these surface coat antigens (scags) were then used to immunize rats. after immunization, sera were assayed in vitro for levels of circulating trypanostatic and trypanocidal antibodies. approximately half of the immune sera had h ... | 1984 | 6363294 |
| rapid and sterilizing effect of penicillin sodium in experimental relapsing fever infections and its ineffectiveness in the treatment of trypanosomiasis (trypanosoma lewisi) and toxoplasmosis. | | 1944 | 17844553 |
| course of trypanosoma lewisi infections in white rats treated with sodium salicylate. | | 1949 | 18111990 |
| trypanosoma lewisi: pyruvate and transketolase activity in normal and thiamine deficient rats. | transketolase and pyruvate changes were studied in rats infected with trypanosoma lewisi and fed complete, thiamine-deficient and pair-fed control diets. regardless of the dietary group, marked increases in pyruvate levels were observed in the infected animals. there were no significant differences in erythrocyte transketolase activity of rats given a full complement diet. significant decreases, however, were observed in the transketolase activity of pair-fed and thiamine deficient rats. the gre ... | 1984 | 6381162 |
| the oxidative metabolism of trypanosoma lewisi in a phosphate-saline medium. | | 1948 | 18869805 |
| changes in the glucose metabolism of trypanosoma lewisi during the course of infection in the rat. | | 1948 | 18869806 |
| the influence of biotin deficiency on the course of infection with trypanosoma lewisi in the albino rat. | | 1947 | 18895742 |
| liver changes in pantothenate-deficient rats infected with trypanosoma lewisi. | | 1948 | 18898002 |
| adult multiplication in trypanosoma lewisi. | | 1947 | 18935409 |
| polyamine oxidase-mediated trypanosome killing: the role of hydrogen peroxide and aldehydes. | trypanosoma lewisi and t. musculi were lysed when incubated with bovine serum in the presence of either spermine or spermidine. similar results were obtained when a fraction from bovine serum containing polyamine oxidase (pao) activity or a commercially available purified beef plasma pao were used in lieu of bovine serum. trypanosomes treated with cytotoxic concentrations of pao-spermine failed to establish infection in rats. these results are similar to those from our previous studies with afri ... | 1984 | 6381596 |
| trypanosoma lewisi: the effect of thymectomy on the production of ablastin and the termination of the parasitaemia in infected rats. | this study investigated the effect of the depletion of t lymphocytes on the production of ablastin and the termination of the parasitaemias in porton strain rats infected with trypanosoma lewisi. weanling rats were thymectomised or sham-thymectomised and then x-irradiated. after allowing 96 days for recovery from these procedures the rats were infected with t. lewisi. the rats were considered to be t lymphocyte depleted if they were unable to mount an antibody response to sheep red blood cells b ... | 1984 | 6388547 |
| trypanosoma lewisi in field rats and its zoonotic importance. | | 1984 | 6389340 |
| redescription of the life cycle of trypanosoma (herpetosoma) lewisi from upper egyptian rats. | | 1984 | 6392437 |
| a note on the pathogenicity of trypanosoma lewisi. | 1. some strains of trypanosoma lewisi may, at times, produce rapidly fatal infections in a large percentage of the rats infected. 2. in such strains of trypanosoma lewisi, a sufficient degree of pathogenicity may persist to warrant the designation of these strains as pathogenic. 3. the pathogenicity of a given strain of trypanosoma lewisi is not constant, but is subject to marked and even sudden variations. | 1914 | 19867780 |
| activity of d-carnitine and its derivatives on trypanosoma infections in rats and mice. | little progress has been made in the treatment of african trypanosomiasis over the past decades. l-carnitine has a major role in glycolysis-based energy supply of blood trypanosomes for it stimulates constant atp production. to investigate whether administration of the isomer d-carnitine could exert a competitive inhibition on the metabolic pathway of the l-form, possibly resulting in parasite replication inhibition, several formulations of this compound were tested on trypanosoma lewisi and t. ... | 2003 | 12847922 |
| in vitro phagocytosis of trypanosoma lewisi by rat exudative cells. | | 1960 | 13758793 |
| a reaction product in infections with trypanosoma lewisi which inhibits the reproduction of the trypanosomes. | 1. in infections with trypanosoma lewisi in the rat there are three manifestations of resistance against the parasite: (1) the retardation and final inhibition of reproduction of the trypanosomes by about the 10th day; (2) a sudden drop in the number of parasites in the blood between the 9th and 15th days; and (3) the total disappearance of the parasites, which terminates the infection and occurs from a week to several months after the first drop in numbers. 2. the first manifestation of resista ... | 1924 | 19868831 |
| studies on bartonella muris anemia of albino rats : i. trypanosoma lewisi infection in normal albino rats associated with bartonella muris anemia ii. latent infection in adult normal rats. | 1. the virus of bartonella muris anemia of splenectomized rats may be transmitted to normal young unoperated rats and rabbits. this confirms the observations of ford and eliot. 2. trypanosoma lewisi infections in normal adult rats are accompanied by an anemia most marked at the height of the infection and the appearance of bartonella muris bodies in the red blood cells. 3. in young rats trypanosoma lewisi may produce death from the severity of the anemia, complicating the disease. the anemic vir ... | 1930 | 19869745 |
| quantitative studies on heterologous sera inducing development of trypanosoma lewisi in mice. | | 1961 | 13762223 |