| preulcerative changes to the pars oesophagea associated with torulopsis glabrata infection in a weaned pig. | | 1989 | 2818364 |
| identification and characterization of mitochondrial translation products in various yeasts and in prototheca zopfii. | mitochondrial genomes of different eucaryotes are not all alike. we have examined mitochondrial translation products in a number of yeasts (candida krusei, hansenula saturnus, rhodotorula glutinis, rhodotorula rubra, torulopsis glabrata and saccharomyces cerevisiae) and in prototheca zopfii, a colorless alga, in order to determine whether certain proteins are invariably synthesized within mitochondria, how different these proteins are, and what additional proteins, if any, might be synthesized b ... | 1985 | 2836096 |
| sensitivity of intergenic regions of yeast mitochondrial dna to single-strand-specific nucleases. | the reactivity of mitochondrial dna (mtdna) sequences from torulopsis glabrata and saccharomyces cerevisiae towards single-strand-specific nucleases has been examined. at-rich stretches located in intergenic sequences from both yeasts were cleaved by nucleases when the sequences were contained in supercoiled plasmid dna. in particular ori/rep sequences from the mtdna of s. cerevisiae were shown to be sensitive to the single-strand-specific nucleases. the locations of the sensitive sites were rel ... | 1988 | 2844609 |
| effects of adenylate cyclase toxin from bordetella pertussis on human neutrophil interactions with coccidioides immitis and staphylococcus aureus. | bordetella pertussis extract that contained adenylate cyclase toxin produced large increases in human neutrophil cyclic amp levels and inhibited their oxidative burst, as reflected by luminol-enhanced chemiluminescence and superoxide release. the adenylate cyclase toxin-containing extract blocked neutrophil-mediated inhibition of n-acetylglucosamine incorporation by arthroconidia of coccidioides immitis in a dose-dependent fashion but had no effect on neutrophil phagocytosis of candida glabrata ... | 1988 | 2894360 |
| fluconazole resistance in candida glabrata. | | 1988 | 2904031 |
| periprosthetic candidal infections following arthroplasty. | candidal infection after prosthetic arthroplasty has been reported in six previous cases, to which four cases are now added. candida albicans was the offending organism in four patients, candida parapsilosis in three, candida tropicalis in two, and candida (torulopsis) glabrata in one. none of the 10 patients had evidence of disseminated candidiasis, and, except for the uniform presence of a prosthesis, other underlying factors that are generally associated with candidal infections were present ... | 1989 | 2916098 |
| [technic for detecting several yeasts in the same sample]. | the frequent association of torulopsis glabrata with other yeasts of the genus candida in the same clinical specimen may lead to false results because of the large number of negative characters in this yeast. we describe here a technique of detection based on the pigmentation of colonies obtained by reduction of triphenyl-tetrazolium chloride added to the sabouraud medium. | 1985 | 2935834 |
| [acute post-stress cholecystitis and torulopsis glabrata septicemia]. | | 1987 | 2950434 |
| [torulopsis glabrata endocarditis after cardiac surgery for heart valve replacement]. | | 1988 | 2967962 |
| diffuse intestinal ulceration after marrow transplantation: a clinicopathologic study of 13 patients. | the cases of 13 allogeneic marrow transplant recipients who had undergone laparotomy for manifestations of severe enteritis were reviewed to determine the causes of the severe intestinal disease and to assess the relation between clinical, histologic, and microbiologic findings. laparotomies were performed a median of 63 days (range, 11 to 273 days) after transplantation for suspected peritonitis, intestinal obstruction, or bleeding. intestinal tissue was available from small bowel resections in ... | 1986 | 3011641 |
| tolerance to and efficacy of itraconazole in treatment of systemic mycoses: preliminary results. | twelve patients with mycotic infections were treated with itraconazole during a one-year period. patients had the following conditions: coccidioidomycosis (three), histoplasmosis (three), mucocutaneous candidosis (two), aspergillosis (three), and urinary tract infection due to torulopsis glabrata (one). the daily dose of itraconazole ranged from 100 to 200 mg. ten of the 12 cases were assessable. clinical improvement was observed in six patients, two with coccidioidomycosis, two with mucocutaneo ... | 1987 | 3027852 |
| molecular probe for identification of medically important candida species and torulopsis glabrata. | a cloned dna fragment from candida albicans containing the gene for the protein actin was used to probe the molecular structure of the actin gene of several medically important yeasts (c. albicans, candida stellatoidea, candida tropicalis, candida pseudotropicalis, candida krusei, candida parapsilosis, candida guilliermondii, and torulopsis glabrata). whole-cell dna from each species was digested with restriction endonucleases, electrophoresed on agarose gels, and transferred to nitrocellulose. ... | 1987 | 3033014 |
| multicenter evaluation of four methods of yeast inoculum preparation. | we initiated a comparative study of four methods of yeast inoculum preparation: a spectrophotometric method, the wickerham card method, a hemacytometer method, and the prompt inoculation system. the variability in inoculum size obtained when each method was applied to two strains each of candida albicans, candida tropicalis, candida parapsilosis, torulopsis glabrata, cryptococcus neoformans, and saccharomyces cerevisiae was analyzed in a single laboratory. each method was performed in triplicate ... | 1988 | 3049651 |
| respiration of medically important candida species and saccharomyces cerevisiae in relation to glucose effect. | strains of medically important candida species (c. albicans, c. tropicalis, c. parapsilosis and c. [torulopsis] glabrata) and saccharomyces cerevisiae were examined for a glucose effect on respiratory activity. reduced o2-consuming ability and a relative decrease in cytochrome type c, as determined by polarography and spectrophotometry, respectively, were observed in glucose-grown s. cerevisiae cells in contrast with acetate- or ethanol-grown cells. in glucose-grown cells of c. glabrata, o2 cons ... | 1988 | 3050010 |
| cilofungin (ly121019), an antifungal agent with specific activity against candida albicans and candida tropicalis. | cilofungin (ly121019) is an antifungal agent that interferes with beta-glucan synthesis in the cells walls of fungi. the activity of this agent against 256 clinical isolates of yeasts was determined. it was found to be very active in vitro against candida albicans (mic for 90% of isolates [mic90], less than or equal to 0.31 microgram/ml; minimal fungicidal concentration for 90% of isolates [mfc90], less than or equal to 0.31 micrograms/ml) and c. tropicalis (mic90, less than or equal to 0.31 mic ... | 1988 | 3058017 |
| drug resistance in candida albicans and candida glabrata. | | 1988 | 3063171 |
| pyrolysis mass spectrometry as a method for inter-strain discrimination of candida albicans. | a claim that candida albicans strains ncpf 3153 and b311 were identical was investigated. authentic strains were shown to be distinct (p less than 0.1%) by pyrolysis mass spectrometry (pyms). of twelve strains, provided as clones of ncpf 3153, seven were authenticated, one yielded an equivocal result and four were distinct from both ncpf 3153 and b311. of eight b311 clones, six were authenticated and two yielded equivocal results. although five non-c. albicans yeast strains were identified as di ... | 1988 | 3076175 |
| growth of bacteria and fungi in total nutrient admixtures. | total nutrient admixtures (tnas) containing dextrose, amino acids, and fat emulsion were evaluated for their ability to support bacterial and fungal growth. the following solutions were tested: a standard adult total parenteral nutrient (tpn) solution with dextrose, amino acids, and electrolytes, a standard neonatal tpn solution with dextrose, amino acids, and electrolytes, a 10% fat emulsion, a 20% fat emulsion, a tna with 40% of the total calories as fat, a tna with 25% of the total calories a ... | 1986 | 3082195 |
| growth and acid production of candida species in human saliva supplemented with glucose. | growth characteristic and acid production of oral isolates of candida albicans and candida glabrata in glucose supplemented and glucose-free, pooled, human whole saliva were examined. both candida species exhibited sigmoidal growth curves in batch cultures of mixed saliva, supplemented with glucose. the growth of candida in saliva was accompanied by a rapid decline in ph from 7.5 to 3.2 over 48 h and the major acidic components initiating and sustaining this ph drop were pyruvates and acetates. ... | 1986 | 3091791 |
| effects of antineoplastic agents on growth, morphology and metabolism of torulopsis glabrata. | the effect of treatment by a number of antineoplastic agents on the growth, ultrastructure and macromolecular synthesis of t. glabrata was studied. many differences were noted in the response of this yeast to these agents. thiotepa and methotrexate inhibited the growth of t. glabrata, while it was resistant to endoxan-asta and vincristine sulphate. a variation of morphological response of t. glabrata was also observed. methotrexate enhanced filamentation while thiotepa influenced the surface str ... | 1986 | 3095646 |
| carriage of candida species in the oral cavity in diabetic patients: relationship to glycaemic control. | to study the possible relationship between the quality of glycaemic control in diabetes mellitus and the carriage of candida species, the candidal carrier status of 412 diabetic patients was examined using an oral rinse technique and correlated with measurements of random blood glucose and total glycosylated haemoglobin. candida was isolated in 210 diabetics (51%) with 13 patients (6%) carrying more than one species. the positive isolates were: candida albicans (89%), candida krusei (2.8%), cand ... | 1987 | 3116189 |
| evaluation of in vitro antifungal activity of ly121019. | ly121019 is a new semisynthetic lipopeptide antifungal agent with potent in vitro fungicidal activity against multiple clinical strains of candida albicans and candida tropicalis but is 10-100 fold less active against torulopsis glabrata and candida parapsilosis. its in vitro activity against candida albicans and candida tropicalis is comparable to that of amphotericin b. the in vitro fungicidal activity of this new agent supports further investigations into its use in treatment of candida infec ... | 1988 | 3132385 |
| comparative in vitro activity of ly121019 and amphotericin b against clinical isolates of candida species. | ly121019 and amphotericin b were equally active in vitro against most clinical isolates of candida albicans and candida tropicalis. higher concentrations of ly121019 were required for inhibition of candida glabrata. other candida species were inhibited by amphotericin b but not by ly121019. | 1988 | 3132386 |
| in vitro activity of ly121019 against candida species and torulopsis glabrata. | | 1988 | 3137054 |
| [a case of emphysematous pyelonephritis caused by escherichia coli and candida glabrata]. | | 1988 | 3150417 |
| candida glabrata (syn. torulopsis glabrata) associated with a chronic hyperplastic lesion of the palate. | a case initially presenting as chronic hyperplastic candidosis is described. after treatment with nystatin on three separate occasions over a seven-year period, a lesion similar to that diagnosed originally occurred in the same site. further examination of this later occurrence showed it to be associated with the imperfect fungus candida glabrata which had a high minimum inhibitory concentration for nystatin (greater than 30 micrograms/ml). the lesion eventually resolved following treatment with ... | 1985 | 3156628 |
| [a rare case of torulopsis glabrata in a patient with aids]. | | 1988 | 3173304 |
| comparison of the quantum ii, api yeast ident, and automicrobic systems for identification of clinical yeast isolates. | the quantum ii yeast identification system (abbott laboratories) is a microprocessor-based spectrophotometric system for identification of clinical yeast isolates within 24 h. we compared the quantum ii system with the api yeast ident (analytab products) and the automicrobic system yeast biochemical card (ams-ybc; vitek systems, inc.) for the identification of 221 clinical yeast isolates, including 120 common clinical isolates (candida albicans, c. tropicalis, c. parapsilosis, torulopsis glabrat ... | 1988 | 3182994 |
| metal-specific synthesis of two metallothioneins and gamma-glutamyl peptides in candida glabrata. | cellular resistance to heavy metal cytotoxicity in most species is mediated by the binding of metal ions either to a cysteine-rich polypeptide in the metallothionein family or to short cysteine-containing gamma-glutamyl peptides. one of these metal binding systems has been found in most organisms studied. however, the yeast candida (torulopsis) glabrata expresses both metallothionein and the gamma-glutamyl peptides for metal detoxification, and each system is regulated in a metal-specific manner ... | 1988 | 3194392 |
| torulopsis glabrata fungaemia. | | 1988 | 3232258 |
| collaborative evaluation in seven laboratories of a standardized micromethod for yeast susceptibility testing. | the new micromethod for yeast susceptibility testing, mycototal, was evaluated with 10 reference strains in seven laboratories. ready-to-use microtitration plates and the same synthetic medium were used with two dilutions of imidazoles, flucytosine, and amphotericin b, permitting the categorization of each strain as susceptible, intermediate, or resistant. the results were compared with the mic for each reference strain, and the repeatability and reproducibility were evaluated. the yeasts tested ... | 1988 | 3235657 |
| torulopsis glabrata in vaginitis. | | 1988 | 3241585 |
| prophylactic oral nystatin and fungal infections in very-low-birthweight infants. | prevention of systemic fungal infection in the very-low-birthweight infant is important since it is associated with a high morbidity and mortality. to determine if oral nystatin administration could prevent fungal colonization and infection, we evaluated 67 preterm infants with birthweights less than 1250 gm. thirty-three infants received 1 ml (100,000 units/ml) of nystatin inside the mouth every 8 hours until 1 week after extubation. oropharyngeal, rectal, blood, and urine cultures were obtaine ... | 1988 | 3276336 |
| variable expression of a surface determinant during proliferation of candida albicans. | the surface expression of an antigenic determinant that is present in the cell wall of candida albicans was investigated with monoclonal antibody 24 (mab24), an immunoglobulin m mab. the proportion of the cell population that expressed the epitope under different growing conditions was determined by indirect immunofluorescence microscopy. more than 90% of stationary-phase yeast cells of strain b311 grown at 28 degrees c expressed the antigen. less than 50% of yeast cells grown exponentially at 2 ... | 1988 | 3276622 |
| antigenic differences in the surface mannoproteins of candida albicans as revealed by monoclonal antibodies. | monoclonal antibodies to candida albicans were prepared with blastoconidia bearing germ tubes used as the immunogen. four antibodies reacted by immunofluorescence with surfaces of c. albicans as well as candida stellatoidea, candida tropicalis, and several strains of c. albicans, but not with torulopsis glabrata. one antibody reacted with saccharomyces cerevisiae. in addition, the monoclonal antibodies precipitated material of approximately 200 kilodaltons when tested against metabolically label ... | 1988 | 3277915 |
| preparation of monoclonal antibodies reactive with beta-1,2-linked oligomannosyl residues in the phosphomannan-protein complex of candida albicans nih b-792 strain. | hybridomas obtained by fusing the spleen cells of balb/c female mice hyperimmunized with heat-killed yeast-form cells of candida albicans nih b-792 strain and a mouse myeloma cell line, p3x63ag8.653, produced antibodies to beta-1,2-linked oligomannosyl residues in the phosphomannan-protein complex of the parent cells. most of these monoclonal antibodies were igm, but about 10% of the hybridomas produced igg1 immunoglobulins. ascites fluid from balb/c mice inoculated with an igg1-producing hybrid ... | 1988 | 3280163 |
| torulopsis glabrata urinary infections: a review. | during a 12-year prospective period 9 referral patients were treated for proved torulopsis urinary infections. of the 9 patients 7 had irritative voiding symptoms and pyuria was present in 8. to estimate incidence of infection, a retrospective review was performed between january 1982 and december 1983. a total of 105 urine specimens from 57 hospitalized patients yielded torulopsis glabrata. two patients suffered symptomatic invasive infections. patients were treated with antifungal therapy only ... | 1988 | 3286891 |
| allergenic cross-reactivity of yeasts. | yeast allergen extracts of candida albicans, c. pseudotropicalis, c. krusei, c. parapsilosis, c. tropicalis, c. guilliermondi, c. humicola, c. norwegica, c. utilis, cryptococcus albidus, geotrichum candidum, pityrosporon pachydermatis, p. ovale, rhodotorula minuta, r. rubra, saccharomyces cerevisiae, torulopsis glabrata and trichosporon cutaneum were investigated regarding their common allergenic properties. the enzyme immunoassay (eia) using rabbit anti-candida albicans antiserum showed remarka ... | 1988 | 3287997 |
| prevention and mycoses in immunocompromised patients. | invasive fungal infections remain a major complication in immunocompromised hosts. the prognosis in these infections is poor, particularly for neutropenic patients with cancer. candidiasis and aspergillosis are common in these patients, and numerous attempts have been made to evaluate potential prophylactic methods. despite the fact that various agents (polyenes and/or imidazoles) and various formulations have been tested, the reported data on their effectiveness are still controversial. no sing ... | 1987 | 3296106 |
| the at spacers and the var1 genes from the mitochondrial genomes of saccharomyces cerevisiae and torulopsis glabrata: evolutionary origin and mechanism of formation. | intergenic sequences represent 63% of the mitochondrial 'long' (85 kb) genome of saccharomyces cerevisiae. they comprise 170-200 at spacers that correspond to 47% of the genome and are separated from each other by gc clusters, orfs, ori sequences, as well as by protein-coding genes. intergenic at spacers have an average size of 190 bp, and a gc level of 5%; they are formed by short (20-30 nt on the average) a/t stretches separated by c/g mono- to trinucleotides. an analysis of the primary struct ... | 1987 | 3301538 |
| candida (torulopsis) glabrata. | candida (torulopsis) glabrata is usually a nonpathogenic fungus living saprophytically with normal flora. however, under special circumstances, the organism can become locally invasive and potentially disseminate. laboratory identification is based on colonial appearance, absence of hyphae, and characteristic biochemical reactions. treatment usually consists of amphotericin b with occasional reports of 5-fluorocytosine usefulness. it is apparent that torulopsis represents yet another "evolving" ... | 1987 | 3308741 |
| analysis of fatty acid composition of candida species by gas-liquid chromatography using a polar column. | the fatty acid composition of representative candida species was examined by gas-liquid chromatography (glc) using a polar column. the major fatty acids were c14:0, c16:0, c18:0 saturated, c16:1 and c18:1 monoenoic series, with or without c18 polyunsaturated acids (c18:2 and c18:3). in torulopsis glabrata and saccharomyces cerevisiae the c18:2 and c18:3 acids were not found, but the c10:0 and c12:0 acids were detected in s. cerevisiae. these results indicated that the candida genus could be dist ... | 1987 | 3309574 |
| [in vitro antifungal activity of nitroxoline. preliminary clinical results]. | nitroxoline is an oxyquinoline derivative with a large antifungical activity. the fungistatic activity of nitroxoline is greater against candida albicans than against torulopsis glabrata, candida tropicalis and candida krusei. the mic are compatible with urinary concentrations of nitroxoline. these preliminary clinical results favor the use of nitroxoline in the management of fungal urinary tract infections. | 1987 | 3309833 |
| torulopsis glabrata vertebral osteomyelitis. case report and review of the literature. | | 1987 | 3310258 |
| parasexual genetics of torulopsis glabrata. | prototrophic hybrids were generated in the asexual yeast torulopsis glabrata by the fusion of spheroplasts derived from parent strains which bore complementing auxotrophic markers. the dna content (per cell) of two hybrids was essentially that predicted by summing the corresponding parental values. uv irradiation of these two hybrids resulted in the formation of sectored colonies with genetic properties consistent with their origin by either mitotic recombination or chromosomal nondisjunction. | 1987 | 3312164 |
| the use of the prompt inoculation system in preparing a standardized yeast inoculum. | one of the most important steps in performing broth dilution susceptibility testing of yeast isolates is the preparation of the starting inoculum. although not specifically developed for yeast inoculum preparation, the prompt inoculation system (3m) provides a novel alternative approach that may provide a more standardized yeast inoculum than previously employed methods. the authors examined the relationship between the number of colonies picked with the prompt inoculation wand and the hemacytom ... | 1987 | 3318388 |
| predictive value of surveillance cultures for systemic infection due to candida species. | weekly fungal surveillance cultures (1,542 cultures) of urine (475), stool (520) and oropharyngeal (547) specimens from 111 patients on the bone marrow transplant and hematologic malignancy services were analyzed. forty-three percent of the patients were colonized by candida albicans and 10.8% by candida tropicalis. there were 22 proven systemic fungal infections, ten due to candida albicans, eight to candida tropicalis, one each to candida pseudotropicalis and torulopsis glabrata, and two to as ... | 1987 | 3326742 |
| degradation of iga1, iga2, and s-iga by candida and torulopsis species. | nine strains, isolated from leukoplakias or normal mucosa of the oral cavity, and representing the species candida albicans, c.tropicalis, and torulopsis glabrata were tested for the capacity to degrade iga1, iga2, and s-iga in liquid cultures. iga fragments were characterized by sds-page of culture supernatants in combination with immunoblotting analysis using antibodies specific for heavy chain and light chain determinants. strains of c.albicans and c.tropicalis were found to express stronger ... | 1987 | 3327361 |
| the inhibitory effect of serum on the growth of torulopsis glabrata. | normal human plasma and serum were found to inhibit the growth of torulopsis glabrata and, to a lesser extent, other yeasts. the factor responsible for the inhibition of t. glabrata was not dialysable, was heat stable at 56 degrees c for up to 4 h and could be partly removed by absorption with viable t. glabrata but not candida albicans. it was fungistatic at low concentrations and fungicidal at high concentrations, stable up to 4 years between -20 degrees c and -70 degrees c, but for only a few ... | 1988 | 3346903 |
| in vitro synergistic activity of ketoconazole with trifluoperazine and with chlorpromazine against medically important yeasts. | combination of ketoconazole and trifluoperazine or chlorpromazine yielded an in vitro synergistic effect on growth inhibition of candida albicans, torulopsis glabrata, cryptococcus neoformans, candida parapsilosis and candida tropicalis. the optimal ph range for the synergistic effects was 7.0-7.6. at ph 5.0 the drug combination was antagonistic. (application for patent protection has been filed). | 1988 | 3391057 |
| hepatic abscesses and fungemia from torulopsis glabrata. successful treatment with percutaneous drainage and amphotericin b. | a 39-year-old man with severe diabetes mellitus, chronic pancreatic insufficiency, intrapancreatic choledochal stricture, and secondary biliary cirrhosis developed postsurgical fungemia and large hepatic abscesses due to torulopsis glabrata. these were treated successfully with a combination of amphotericin b and percutaneous drainage of the liver abscesses. we believe this is the first reported case of such infection due to this normally saprophytic agent. | 1987 | 3443738 |
| cytodiagnosis of candida organisms in cervical smears. | cervical smears and cervical scrapings cultured on sabouraud agar from 31 women suspected of having candida genital infections were examined in a study of the cytomorphology of this fungal infection in cervical smears. of the 31 samples, 20 (64.5%) grew c. albicans in culture. one sample (3.2%) grew c. paratropicalis, 2 (6.4%) grew mixed c. albicans and torulopsis glabrata and 2 (6.4%) grew t. glabrata alone. of the 25 fungus-positive samples, 20 (80%) had fungus-positive cervical smears and 5 ( ... | 1986 | 3465137 |
| [pulmonary candida manifestation with cavitation in immunosuppressed patients]. | the roentgenologic pattern of the pulmonary manifestation of candida species, resulting in a rapid development of pulmonary cavitations with mycetoma-like structures, was described in three patients. all patients, undergoing antineoplastic chemotherapy because of acute leukemia, presented with fever and expectoration, which were resistant to various antibiotic regimes. cultures of blood and urine were sterile; but torulopsis glabrata, a candida species, was found in multiple cultures of the sput ... | 1987 | 3472265 |
| production and characterization of agglutinating monoclonal antibodies against predominant antigenic factors for candida albicans. | two clones, ca4-2 and ca5-4, which produced agglutinating monoclonal immunoglobulin m (igm) antibodies (mabs) against mannan antigens of candida albicans serotype a, were established. the specificity of each mab was determined by slide agglutination tests for cross-reactivity patterns against the homologous and six other strains of candida and a strain of torulopsis: c. albicans serotype b, c. tropicalis, c. guilliermondii, c. krusei, c. parapsilosis, c. pseudotropicalis, and torulopsis glabrata ... | 1986 | 3519660 |
| multiple brain abscesses caused by torulopsis glabrata in an immunocompromised patient. | | 1986 | 3528847 |
| influence of growth conditions on cell surface hydrophobicity of candida albicans and candida glabrata. | the effect of cultural conditions on cell surface hydrophobicity of candida albicans and candida glabrata was tested. c. albicans cells grown at room temperature were more hydrophobic than cells grown at 37 degrees c. no consistent pattern was observed with c. glabrata. relative hydrophobicity was found to vary with the growth phase and growth medium for both species. the implications for pathogenesis studies are discussed. | 1986 | 3531018 |
| [comparative sensitivity of yeasts to antifungal agents using a standardized micromethod]. | the comparative susceptibility of 1 850 yeast strains belonging to 8 species was determined. the standardized micromethods used allows determinations of minimal inhibitory concentrations (mics) or categorized sensitivities for two different concentrations (ab). overall results showed that amphotericin b (amb) is the most active agent, followed by the various imidazoles. 5-fluorocytosine (5fc) was the least effective drug, with 68% susceptible strains. however, results varied widely across specie ... | 1986 | 3534739 |
| drug resistance in the opportunistic pathogens candida albicans and candida glabrata. | there are three major classes of antifungal drug used to treat patients suffering from topical and systemic infections caused by candida albicans. both the polyene macrolide antibiotics and the synthetic imidazole derivatives interact with membranes of sensitive organisms causing an impairment of function and cessation of growth. it is possible to obtain mutants of c. albicans resistant to these drugs but they are not a clinical problem. this may result from the fact that the organism is diploid ... | 1986 | 3539907 |
| comparison of sabouraud dextrose and pagano-levin agar media for detection and isolation of yeasts from oral samples. | the sensitivities of sabouraud dextrose agar and modified pagano-levin agar for the primary isolation of yeasts and the recovery of multiple yeast species from single clinical samples were compared by using oral-rinse samples. although there was a highly significant positive correlation between the numbers of yeasts recovered from both media, modified pagano-levin agar was far superior in detecting multiple yeast species in a single sample. of 150 oral samples containing yeasts, 23 (15.3%) conta ... | 1987 | 3539988 |
| yeast species and biotypes associated with oral leukoplakia and lichen planus. | of 36 patients, 17 had oral leukoplakia, including homogeneous and nonhomogeneous types, and 19 had reticular lesions of oral lichen planus. a sample of yeast flora in each patient was taken from the pathologic lesion as well as from normal-appearing mucosa. the isolated yeasts were identified according to species level, and identification was extended beyond the species level for one species, candida albicans, to reveal the biotype by means of the odds and abbott procedure comprising tests for ... | 1987 | 3543797 |
| [interactions between the pathogenic fungi candida and torulopsis and the deadly strains of saccharomyces cerevisiae and torulopsis glabrata]. | | 1986 | 3550322 |
| [fungal urinary infection: report no. 1]. | clinical studies were performed on 115 fungal strains isolated from the urine of 36 patients. the predisposing factors were fungal urinary tract infections, antibiotics and indwelling catheter. forty five strains of the 115 strains were candida albicans, the most prevalent, followed by 25 strains of c. tropicalis and 22 strains of trichosporon beigelii. species of torulopsis were rare, only 5 strains were isolated. sixty strains (56%) co-existed with bacteria in urine. the co-existing bacteria m ... | 1986 | 3565191 |
| fungal spondylitis. a case of torulopsis glabrata and candida tropicalis infection. | a case of spondylitis due to torulopsis glabrata and candida tropicalis is reported. fungal osteomyelitis should be suspected in the presence of predisposing factors, such as long antibiotic treatment or reduced immune defense. | 1986 | 3577731 |
| susceptibility of torulopsis glabrata in the presence of six antifungal agents determined by comparison of growth at several phs. | we describe a method using an automated system whereby fungistatic activities can be determined in several conditions. the process was adapted to torulopsis glabrata, and it showed that benzalkonium chloride, chlorhexidine gluconate, and thimerosal preserve fungistatic activities in acidic medium, whereas acidification reduces the activity of povidone iodine and poloxamer. | 1987 | 3579273 |
| torulopsis glabrata osteomyelitis. a case report. | skeletal infection involving torulopsis glabrata is extremely rare. a 66-year-old woman developed torulopsis glabrata osteomyelitis during a course of prolonged antibiotic therapy for staphylococcal pneumonia that occurred as a postoperative complication of a total knee arthroplasty for osteoarthritis. roentgenograms and a biopsy sample revealed a destructive inflammatory lesion of the vertebrae. the presence of the yeast organism in the lesion was demonstrated definitively by culture and tissue ... | 1987 | 3581574 |
| cholecystitis due to torulopsis glabrata. | | 1987 | 3598219 |
| [laboratory and clinical study of intravenous miconazole]. | laboratory and clinical study was carried out on miconazole (mcz), a new synthetic imidazole. the antifungal activity of mcz was studied and expressed as mics for clinical isolates. the drug proved to have the highest activity against cryptococcus neoformans, with mics of no more than 0.16 micrograms/ml for all isolates of this species. mics of torulopsis glabrata were 0.08-5 micrograms/ml for all isolates and those of candida albicans and candida tropicalis were 5-20 micrograms/ml for more than ... | 1987 | 3599380 |
| esophageal ulcers caused by torulopsis glabrata in a patient with acquired immune deficiency syndrome. | esophagitis due to an opportunistic infection in an immunocompromised host is not unusual. this is frequently attributed to candida albicans. torulopsis glabrata is similar however taxonomically distinct from c. albicans. although found to be pathogenic in various organs, to date there have been only four reported cases of t. glabrata esophagitis. none of these was associated with acquired immune deficiency syndrome. the present paper discusses a patient with acquired immune deficiency syndrome ... | 1987 | 3605036 |
| torulopsis (candida) glabrata endocarditis involving a bovine pericardial xenograft heart valve. | | 1986 | 3632965 |
| possible mycological etiology of oral mucosal cancer: catalytic potential of infecting candida albicans and other yeasts in production of n-nitrosobenzylmethylamine. | yeasts were isolated from 12 cases of oral precancerous lesions (leukoplakia and erythroleukoplakia) by sampling the lesion as well as normal mucosa of each patient, yielding 21 strains of candida albicans belonging to 15 biotypes, two strains of c. tropicalis, one strain of c. parapsilosis and two strains of torulopsis glabrata. biopsies were obtained from the lesions for histologic examination. the catalytic potential of the yeast strains to form n-nitrosobenzylmethylamine (nbma) from the prec ... | 1987 | 3652390 |
| catheter-related thrombophlebitis of the superior vena cava caused by candida glabrata. | | 1987 | 3673066 |
| isolation of mutants of candida glabrata resistant to miconazole. | elucidation of the mode of action of azole antifungals would be aided by studying resistant mutants. it is difficult to obtain mutants of candida albicans in the laboratory, and there have only been a few studies on clinical isolates which seem to be resistant because of impaired drug uptake. c. glabrata, unlike c. albicans, is haploid and more likely to give rise to resistant variants. over 30 mutants have been isolated by selection with miconazole on solid medium and have mics of miconazole ab ... | 1987 | 3691159 |
| candida chorioamnionitis diagnosed by amniocentesis with subsequent fetal infection. | isolation of candida albicans from the vaginal secretions of pregnant women occurs with an incidence of 5-23%. intrauterine infection caused by candida during pregnancy is relatively rare; only 81 cases, all diagnosed after delivery, have been reported. we report six cases of candidal chorioamnionitis diagnosed by amniocentesis and confirmed by histologic studies, associated with preterm labor and delivery of five viable infants. three of the six maternal patients had intrauterine contraceptive ... | 1986 | 3718642 |
| candida glabrata meningitis. | we have reported an unusual case of candida glabrata meningitis causing acute changes in mental status in a chronically ill, elderly patient with non-insulin-dependent diabetes mellitus. candida glabrata was identified by gram stain, culture, and fermentation pattern from the csf. although the patient died of foreign body aspiration, an excellent clinical response was initially obtained with amphotericin b and 5-flucytosine. this is the first report of a symptomatic candida glabrata meningitis. | 1986 | 3726596 |
| attributes of microorganisms that contribute to recurrence and intractability of vaginal mycosis. | recurrence or intractability of vaginal mycosis may be ascribable to various factors. attributes of microorganisms that contribute to recurrence and intractability of vaginal mycosis have not fully been elucidated. we studied this problem by means of a modern fungal identification method, strict measurement of the minimum inhibitory concentration and close clinical analysis. as for the detection rate for candida albicans (c. alb.) and torulopsis glabrata (t. glab.) as pathogens of vaginal mycosi ... | 1986 | 3746030 |
| vertebral osteomyelitis due to candida glabrata. a case report. | | 1986 | 3747503 |
| [opportunistic pneumopathy caused by torulopsis glabrata]. | yeasts are taking a growing place in the development of opportunistic pneumonias in a hospital environment. we report a case of pneumonia due to torulopsis glabrata in a patient of 58 years in complete remission from a malignant oesophageal tumour after surgery and radiotherapy, and not given immunosuppressive treatment. | 1986 | 3809700 |
| torulopsis glabrata infection in immunocompromised children. | | 1987 | 3810222 |
| candidacidal factors in murine bronchoalveolar lavage fluid. | respiratory secretions provide an efficient method for protecting the large surface area of the lower respiratory tract. to determine whether lung secretions contribute to antifungal defenses, we tested bronchoalveolar lavage fluid for fungicidal activity. candida albicans (blastoconidia) was incubated in unconcentrated cell-free lavage fluid from swiss webster mice and then cultured quantitatively to measure residual viability. in control buffer the residual fractions of viable fungi were 1.03 ... | 1987 | 3818084 |
| [in vitro evaluation of natamycin sensitivity of candida and torulopsis glabrata strains isolated from the genital tract]. | | 1985 | 3873649 |
| evaluation of the new mycotube test-kit for yeast identification. | the performance of a modified mycotube test for the identification of yeasts was evaluated using standard biochemical tests as reference. one hundred and eighty strains belonging to 12 medically important species (15 strains each) were tested. the overall rate of identification was 72%, and rose to 87.8% when macroscopic and microscopic morphologic features were also considered; a 100% rate was obtained with candida albicans, candida krusei, candida parapsilosis, candida pseudotropicalis, candid ... | 1985 | 3886377 |
| use of immunoblotting to identify antigenic differences between the yeast and mycelial phases of candida albicans. | western blotting was applied to the analysis of candida albicans in the yeast and mycelial phases in an attempt to recognise mycelial specific antigens which might be of serodiagnostic value. the antisera were prepared in rabbits by immunising them with pressates of c albicans type a nctc 3153 in the yeast phase or the mycelial phase. these were blotted against c albicans in the yeast and mycelial phases and the yeast phase of c parapsilosis, c krusei, c tropicalis, and torulopsis glabrata. cros ... | 1985 | 3891792 |
| evaluation of abbott quantum ii yeast identification system. | the identity of each of 239 yeasts, encompassing 9 genera and 30 species, was determined with the quantum ii and api 20c identification systems. with api 20c results accepted as being correct, quantum ii proved to be 92% accurate in identification of common isolates, e.g., candida albicans and torulopsis glabrata, but only 73% effective with less frequently encountered yeasts, e.g., trichosporon beigelii and rhodotorula glutinis. overall, quantum ii was 86% as accurate as api 20c for the yeast i ... | 1985 | 3900130 |
| var1 gene on the mitochondrial genome of torulopsis glabrata. | we have cloned and sequenced a region of the torulopsis glabrata mitochondrial genome homologous to the saccharomyces cerevisiae var1 gene (var1sc). an open reading frame that could encode a protein of 339 amino acids was found with 72.7% amino acid and 85.3% nucleotide sequence homology to the s. cerevisiae var1 gene. the t. glabrata gene (var1tg) is transcribed yielding two stable rnas, a more abundant 13.5 s rna and a less abundant 18 s species. we have also identified a candidate for a t. gl ... | 1985 | 3900417 |
| fungal infections in liver transplant recipients. | sixty-two adults who underwent orthotopic liver transplantations between february 1981 and june 1983 were followed for a mean of 170 days after the operation. twenty-six patients developed 30 episodes of significant fungal infection. candida species and torulopsis glabrata were responsible for 22 episodes and aspergillus species for 6. most fungal infections occurred in the first month after transplantation. in the first 8 weeks after transplantation, death occurred in 69% (18/26) of patients wi ... | 1985 | 3901440 |
| quantification of medically important candida species and torulopsis glabrata by a spiral inoculation system: correlation with pour plate and spread plate methods. | a new method of quantifying candida spp. and torulopsis glabrata suspensions, the spiral inoculation system, was studied to compare its accuracy, efficiency, and cost with the standard pour plating and spread plating methods. concentrations of yeast suspensions ranging from 10(2) to 10(5) cfu were quantified simultaneously by the three methods. linear regression analysis was used to determine the correlation between the spiral inoculation system and pour plating and between the spiral system and ... | 1985 | 3902877 |
| protection by candida albicans of staphylococcus aureus in the establishment of dual infection in mice. | candida albicans has been shown to stimulate infection in mice by a number of bacteria when both organisms are inoculated intraperitoneally (e. carlson, infect. immun. 39:193-197, 1983). when subcutaneous and intraperitoneal inoculations were given with staphylococcus aureus and c. albicans injected at opposite sites, mixed infection was established at the site of fungal inoculation but not at the site of the bacterial injection. histopathologic evaluation of tissues for the presence of c. albic ... | 1985 | 3905609 |
| comparative trial of ketoconazole and nystatin for prevention of fungal infection in neutropenic patients treated in a protective environment. | in a randomized trial we compared ketoconazole (400 mg once daily, 27 patients) and nystatin (3 x 10(6) units four times daily, 29 patients) for prevention of fungal infection in neutropenic patients undergoing marrow transplantation in a protective environment. fewer weekly surveillance cultures contained candida species in ketoconazole recipients than in nystatin recipients (70 [26%] of 274 vs. 151 [47%] of 322; p less than .001). when all fungi were considered, the difference in colonization ... | 1985 | 3905986 |
| symposium on infections in the compromised host. the leukemias. | the treatment of acute leukemia in the adult causes prolonged and profound granulocytopenia. when the patient has less than 100 granulocytes per microliter, the risk of life-threatening infection is extremely high. major infections include bacteremia, pneumonia, pharyngitis, esophagitis, colitis, perianal or perirectal lesions, and cellulitis. the major organisms are gram-negative bacilli (especially pseudomonas aeruginosa, escherichia coli, and klebsiella pneumoniae), gram-positive organisms (s ... | 1985 | 3919366 |
| conditioned medium from stimulated mononuclear leukocytes augments human neutrophil-mediated killing of a virulent acanthamoeba sp. | human neutrophils in the presence of serum containing anti-amoeba antibody either lacked amoebicidal activity or were poorly amoebicidal for acanthamoeba culbertsoni. in contrast, neutrophils preexposed for 1 h to supernatants from human peripheral blood mononuclear leukocytes (mnls) stimulated with phytohemagglutinin demonstrated significant amoeba killing in the presence of serum containing anti-acanthamoeba antibodies. supernatant from mnl cultured in the absence of phytohemagglutinin were no ... | 1986 | 3943902 |
| antifungal activity of some mediterranean algae. | the antifungal activity of 15 mediterranean algae species on some dermatophyte strains (epidermophyton floccosum, microsporum canis, m. gypseum and trichophyton mentagrophytes) and pathogenic yeasts (candida albicans, c. guillermondii, c. krusei, c. tropicalis and torulopsis glabrata) has been tested following a modification of aubert's technique. among the algae species studied, falkenbergia rufolanosa is the most active in front of all the fungi tested. | 1986 | 3960102 |
| isolation and detection of multiple yeasts from a single clinical sample by use of pagano-levin agar medium. | a total of 15,234 clinical samples were tested on modified pagano-levin agar medium to detect multiple yeast species within a single sample. samples containing more than one yeast species were estimated to be 8.0% of the total. the most frequent combination of different yeasts was candida albicans and torulopsis glabrata. | 1985 | 3973001 |
| assessment of head-space gas-liquid chromatography for the rapid detection of growth in blood cultures. | blood for transfusion was inoculated with between 10(0) and 10(2) colony-forming units (cfu) per ml of each of 59 microbial isolates and added to cooked meat broth. at intervals up to 72 h incubation, the cultures were examined by conventional visual inspection and automated head-space gas-liquid chromatography (hs-glc). forty-six isolates including all those examined of staphylococcus aureus, streptococcus pyogenes, s. pneumoniae, s. faecalis, s. milleri, s. mitior, s. mitis, s. salivarius, s. ... | 1985 | 3988854 |
| production of ethanol from infant food formulas by common yeasts. | four common yeasts (candida albicans, candida tropicalis, torulopsis glabrata and saccharomyces cerevisiae) were combined with five infant food formulas and/or supplements (isomil, nutramigen, 5% glucose, coca cola and similac) and incubated at 37 degrees c. gas chromatography was used to measure ethanol production after 24 and 48 h incubation. the quantities of ethanol produced suggest a possible explanation for patients exhibiting the 'auto-brewery syndrome' and raises interest in the role aut ... | 1985 | 3997687 |
| inhibitory effects of chlorpromazine on candida species. | chlorpromazine was tested for antifungal activity by using candida albicans and standard assays. the mic of chlorpromazine was 35 micrograms/ml; the minimal fungicidal concentration was also 35 micrograms/ml. the minimal effective concentration was 2.2 to 3.5 micrograms/ml (using assays based on quantitative cultures and growth). there was a slight positive interaction between chlorpromazine and amphotericin b but no interaction between chlorpromazine and rifampin. chlorpromazine also inhibited ... | 1985 | 4015066 |
| specific inhibition of fungal sterol biosynthesis by sf 86-327, a new allylamine antimycotic agent. | sf 86-327 is a new antimycotic agent of the allylamine type. its primary action appears to be the inhibition of ergosterol biosynthesis at the point of squalene epoxidation, as was previously found with the related compound naftifine. biosynthesis was measured by incorporation of [14c]acetate into sterols in cells of candida albicans, candida parapsilosis, torulopsis glabrata, and the dermatophyte trichophyton mentagrophytes. there was a positive correlation between the sf 86-327 concentrations ... | 1985 | 4039119 |
| location of transcriptional control signals and transfer rna sequences in torulopsis glabrata mitochondrial dna. | determination of sequences from the nine regions separating the large genes in the 19-kbp mitochondrial dna from torulopsis glabrata has led to the identification of 23 trna genes and to the recognition of two types of short repeated sequence implicated in mitochondrial genome expression. the two short repeated sequences are a nonanucleotide motif, 5'-tataagtaa-3' and a dodecanucleotide motif, 5'-tataatattctt-3'. by rna sequence determination it has been found that primary transcripts of the sma ... | 1985 | 4040462 |
| soft tissue abscess caused by torulopsis glabrata and lactobacillus. | | 1985 | 4040653 |
| endocarditis due to torulopsis glabrata. | | 1971 | 4102273 |
| observations on budding cells of torulopsis glabrata. | | 1971 | 4103467 |