| controlled trial of 6-month and 8-month regimens in the treatment of pulmonary tuberculosis. first report. | four short-course antituberculosis regimens allocated at random were studied; (1) streptomycin, isoniazid, and rifampin given daily for 6 months; (2) these 3 drugs plus pyrazinamide given daily for 2 months, followed by twice-weekly administration of streptomycin, isoniazid, and pyrazinamide; (3) a regimen that differed from regimen 2 only in that ethambutol replaced pyrazinamide, and (4) streptomycin plus isoniazid plus rifampin plus pyrazinamide given 3 times per week for 4 months, followed by ... | 1978 | 100029 |
| an assessment of the place of follow-up pulmonary tuberculosis. | i n 1971--4 forty-four patients were found to have drug-susceptible tubercle bacilli in their sputum more than one year after a previous positive result. comparison of their case records with those of 45 controls showed that inadequate chemotherapy was by far the most important cause of relapse. most patients who have had adequate chemotherapy for pulmonary tuberculosis should be discharged. patients who have certain risk factors or who have had inadequate or irregular chemotherapy should be fol ... | 1978 | 100128 |
| [nomenclature of tuberculosis bacilli. the status of bcg. tuberculins and other mycobacterins]. | | 1978 | 100221 |
| [experimental pulmonary cavity formation (author's transl)]. | | 1978 | 100644 |
| [treatment of bronchial lesions in pulmonary tuberculosis with primary drug resistance of mycobacteria]. | | 1978 | 100778 |
| [immunological changes after bcg vaccination and infection with virulent mycobacterium tuberculosis]. | | 1978 | 100780 |
| tuberculosis in kenya: a second national sampling survey of drug resistance and other factors, and a comparison with the prevalence data from the first national sampling survey. an east african and british medical research council co-operative investigation. | a survey was carried out in 1974 in the same random sample of 11 of 30 districts in kenya that were surveyed in 1964, to obtain information on (a) the proportion of patients with pulmonary and with extra-pulmonary tuberculosis, (b) the prevalence of bacteriologically-positive pulmonary tuberculosis, (c) the prevalence of initial and acquired drug resistance, (d) the radiographic extent and type of pulmonary disease, and (e) the changes that had occurred in the 10-year period. of 1490 patients, 8 ... | 1978 | 100917 |
| comparison of various measures of sensitivity of m. tuberculosis to ethambutol. | a sensitivity test for ethambutol was standardised, and performed on cultures isolated from patients before and after the start of chemotherapy with ethambutol and isoniazid. a discrimination type of approach was employed and three criteria of resistance were evolved: (a) growth of 20 colonies or more on ethambutol 4 microgram/ml, using a standard inoculum; (b) a proportion of 25% or more on ethambutol 1.4 microgram/ml; (c) a proportion of 5% or more on ethambutol 2 microgram/ml. the mic definit ... | 1978 | 100918 |
| host-phage relationships in the genus mycobacterium and their clinical significance. | progress made during the last 15 years in the studies on the relationships between mycobacteria and their bacteriophages is reviewed. the basic biology of the phages and the applications of studies on adaptation and host range are discussed in relation to the development of phage typing systems for epidemiological purposes. the nature of lysogeny, its natural occurrence, its experimental establishment, the effect of the lysogenic state on the host bacterium and the evidence that lysogenic mycoba ... | 1978 | 100919 |
| primary antituberculous drug resistance in hawaii, 1957 to 1977. | a study of primary antituberculous drug resistance in hawaii was conducted from 1957 to 1977 to determine the incidence of primary resistance with respect to time. a total of 1,869 initial cultures of mycobacterium tuberculosis submitted to leahi hospital in honolulu were screened to identify drug resistance. of 256 patients who excreted resistant bacilli, only 55 had no history of previous antituberculous chemotherapy. the frequencies of primary drug resistance from july 1957 to july 1977 were ... | 1978 | 101107 |
| induction of antitumor activity in mice presensitized with mycobacterium by immunization with tuberculin-coated tumor. | | 1978 | 101417 |
| isolation and characterization of the monounsaturated long chain fatty acids of mycobacterium tuberculosis. | the positions of double bond in the monounsaturated c15-c32 fatty acids of mycobacterium tuberculosis h37ra were established by gas chromatography/mass spectrometry of the ozonized esters and their pyrrolidide derivatives. the monounsaturated c15-c21 fatty acids had the double bond primarily at the delta 9 position while the monounsaturated longer chain fatty acids (c22-c32) had the double bond in several positions. many of the latter acids, especially the odd-numbered series, were very complex ... | 1978 | 101728 |
| drug resistant tuberculosis in new zealand. | strains of m. tuberculosis resistant to one or more of the antituberculous drugs have not been common in new zealand in the past. there is however, a high incidence of drug resistant tuberculosis in western samoa, 50 percent of cultures tested showing drug resistance and half of these are resistant to two or more drugs. a change from the usual initial treatment is suggested for samoan patients with tuberculosis in new zealand. | 1978 | 101915 |
| [recurrence of pulmonary tuberculosis in poland. 2. risk factors]. | | 1978 | 101975 |
| [importance of bacteriological examinations for mycobacterium tuberculosis of certain groups of population with increased risk of contracting tuberculosis]. | | 1978 | 101984 |
| [biological properties of selected drug-resistant strains of mycobacterium tuberculosis]. | | 1978 | 101985 |
| tuberculosis in south cleveland 1968--74. a laboratory based survey. | | 1978 | 102006 |
| characteristics of hospitalized tuberculous patients today. | the characteristics of 149 patients with tuberculosis consecutively discharged from the tuberculosis service of the university of tennessee hospital in 1975 and 1976 were evaluated. the results of this study indicate the presence in this group of advanced age, alcohol abuse, debility from multiple chronic diseases, drug resistance, and recalcitrance. despite the unfavorable circumstances surrounding these patients, 118 patients showed bacteriologic and/or roentgenographic evidence of improvement ... | 1978 | 102036 |
| [catalases of mycobacteria as antigens. i. isolation, purification and characterization of catalases from different mycobacteria (author's transl)]. | preparations of catalase isolated from the strains m. tuberculosis, m. kansasii and m. bovis bcg are produced for testing their antigenic activity. after desintegration of the bacteria the highest activity remained in the precipitation with 50% saturated ammonium sulphate solution. the further purification of the catalase-fractions occurred with the aid of column chromatography on sephadex g 200 and deae-sephadex-a 50 after ultrafiltration. in this way the relative activity increased in m. tuber ... | 1978 | 102090 |
| [comparative study of virulence of mycobacterium xenopi and other mycobacteria in the rabbit (author's transl)]. | | 1978 | 102134 |
| pathobiodynamics: changes in ascorbate metabolism in rats with peripheral inflammation. | | 1978 | 102321 |
| [current status of the problem. i. epidemiology of tuberculosis]. | | 1978 | 102388 |
| tuberculous meningitis. | to evaluate modern treatment and identify important factors influencing the outcome of tuberculous meningitis, clinical and laboratory findings in 52 patients aged from 9 months to 68 years have been reviewed. patients were classified by clinical criterions at admission and at the start of treatment. delay in commencing treatment was associated with deterioration and consequently poorer prognosis, but some severely ill patients made a good recovery. forty-four survivors (85%) recovered, and only ... | 1979 | 102806 |
| pott's disease in heroin addicts. | five cases of tuberculous vertebral osteomyelitis occurred in heroin addicts at st luke's hospital center between 1955 and 1975. all patients were men, and four were between 19 and 33 years of age. in contrast with the indolent onset typical to pyogenic or fungal vertebral osteomyelitis in heroin addicts, patients with pott's disease had an acute toxic reaction, with fever, back pain, weight loss, and night sweats. neurologic abnormalities, uncommon with pyogenic or fungal vertebral infection, o ... | 1979 | 102808 |
| [a comparison of the time of in vivo resistance development of tubercle bacilli to rifampicin, kanamycin, ethionamide, lividomycin, and enviomycin (tuberactinomycin-n) in patients with chronic cavitary tuberculosis (author's transl)]. | | 1978 | 102861 |
| antituberculous effect of some imidazole derivatives. | | 1978 | 102862 |
| [detection of pathogenic mycobacteria in the environment of the medical units and of the slaughter-house of an african town (author's transl)]. | the authors have made investigations about the presence of pathogen mycobacteria in puddles of rain water and in rill waters of sanitary formations and municipal slaughter-house of yaoundé. 19 strains of pathogen mycobacteria have been isolated from 84 water samples : 15 m. tuberculosis strains, especially present in the environment of sanitary formations, 4 m. bovis strains, especially present in the environment of the slaughterhouse. the third part of isolated m. tuberculosis strains belongs t ... | 1978 | 102900 |
| [mycobacteriophage typing of acid-fast strains isolated from patients in various provinces of poland]. | | 1978 | 103079 |
| [healing of destructive pulmonary tuberculosis depending on bacteriostatic effect of various methods of treatment]. | | 1978 | 103090 |
| [virulence of polyresistant strains of mycobacterium tuberculosis]. | | 1978 | 103091 |
| [pathomorphology of tuberculous and post-tuberculous changes depending on the l-transformation of mycobacteria in the patient's body]. | | 1978 | 103092 |
| [acquired resistance of mycobacterium tuberculosis to rifampicin]. | | 1978 | 103148 |
| [special aspects of tuberculosis in exposed personnel]. | | 1978 | 103203 |
| isolation of tuberculin peptides from tuberculin purified protein derivative (ppd). | tuberculin purified protein derivative (ppd) obtained from the filtrate of mycobacterium tuberculosis was hydrolysed with proteinase, trypsin, or chymotrypsin. each hydrolysate consisted of a tuberculin peptides mixture (tpm). from each tpm 16 fractions were obtained by ion-exchange chromatography on dowex 50w-x8 but only one fraction was isolated from each of the 16 fractions which showed tuberculin activity in guinea pigs sensitized with m. bovis (bcg) or m. tuberculosis. this fraction was des ... | 1978 | 103608 |
| incidence of pulmonary tuberculosis and change in bacteriological status of cases at shorter intervals. | | 1978 | 103812 |
| immunological method to differentiate between antigens of tubercle bacilli, other mycobacterial species, and non-acid-fast bacteria. | sera from rabbits immunized with sonicates of mycobacterium bovis bcg were passed through an immunoadsorbent made of a soluble bcg extract to make partially purified antibodies to bcg. these antibodies were in turn used to prepare an immunoadsorbent through which the bcg extract was passed. the partially purified antigenic material was radiolabeled and subjected to electrophoresis in acrylamide gels. one of the radiolabeled fractions isolated (bcg-c) was found to bind to antibodies to bcg and h3 ... | 1978 | 103823 |
| [action of preparation k and its components on the causative agent of tuberculosis]. | | 1978 | 104131 |
| [lymph node tuberculosis--today]. | the peripheral tuberculosis of the lymph nodes on the neck, in the axilla and on the groin is described in its present epidemiological situation, its pathogenesis, diagnosis and therapy. nowadays the tuberculosis of the lymph nodes most frequently occurs at older age and in women. in most cases the m. tuberculosis is the causative organism. the differential diagnosis must take into consideration many possibilities and sources of error--also for the following therapy and expert opinion--, in most ... | 1978 | 104459 |
| isolation of tubercle bacteria using ogawa egg medium modified by addition of tween 80. | a modified medium was developed by altering the composition of 3 per cent ogawa egg medium and adding tween 80. isolation of tubercle bacilli using this medium, in general, showed better growth and colines became visible earlier than the original medium, but there was no improvement in the positive rate. | 1978 | 104475 |
| a continuing survey of tuberculosis primary drug resistance in the united states: march 1975 to november 1977. a united states public health service cooperative study. | | 1978 | 104647 |
| [is bacteriophage typing of mycobacterium tuberculosis of practical value?]. | | 1978 | 104757 |
| recovery from tuberculous meningitis. | | 1979 | 104758 |
| [adjuvant activity and antigenicity of maf3 determined by the lymphocyte blastogenesis (author's transl)]. | | 1978 | 105172 |
| effect of mycobacterial water-soluble adjuvant (maf3) on the immune response of guinea pigs to the hapten-carrier conjugates. | | 1978 | 105230 |
| [action of iodophoric disinfectants and chlorhexidine-containing preparations on human-type tubercle bacilli]. | | 1979 | 105345 |
| [bacteriostatic activity of the blood in pulmonary tuberculosis and its clinical significance]. | | 1979 | 105352 |
| [detection of mycobacterium tuberculosis with the parallel use of various methods]. | | 1979 | 105353 |
| [prognostic value of isolation of drug-resistant mycobacterium tuberculosis]. | | 1978 | 105475 |
| [the use of mycobacteria in the estimation of the concentration of antibiotics, antimycotics and antituberculotics (author's transl)]. | the possibility of using the rapid resistance test to determine the levels of antibiotic, antimycotic and antituberculotic drugs is systematically investigated. as a rule the incubation time reduced to seven days for tubercel bacilli results in a lower inhibitor concentration (mic) than with other microbiological methods used in tuberculosis diagnostics due to a lower inactivation of the drugs. the mic of antibiotics and antituberculotics is found between 0.02 and 15 microgram/ml; for penicillin ... | 1978 | 105479 |
| cell-mediated immunity on secretory surfaces. | | 1978 | 105574 |
| [persisters and chemotherapy in tuberculous infection (author's transl)]. | | 1978 | 106180 |
| [decrease of isoniazid-resistant mycobacterium strains]. | | 1979 | 106354 |
| [comparative study of methods for the bacterioscopic diagnosis of tuberculosis and of methods for determining drug sensitivity]. | | 1979 | 106383 |
| [effect of temperature fluctuations in sending pathological material on the inoculability of mycobacterium tuberculosis]. | | 1979 | 106384 |
| [biological characteristics of the specific and nonspecific microflora in osteoarticular tuberculosis]. | | 1979 | 106385 |
| [microbiological studies in the clinical picture of osteoarticular tuberculosis]. | | 1979 | 106386 |
| [study of the milk of nursing mothers with tuberculosis for mycobacterium tuberculosis]. | | 1979 | 106387 |
| cross-reactions between mycobacteria. ii. crossed immunoelectrophoretic analysis of soluble antigens of bcg and comparison with other mycobacteria. | cross-reactions between mycobacterium bovis bcg and various other mycobacteria, nocardia asteroides, corynebacterium pyogenes and listeria monocytogenes were studied by incorporating antibodies against these bacteria in the intermediate gel of a crossed immunoelectrophoretic system with bcg antigen and anti-bcg antibodies. in the bcg reference system forty-four distinct antigenic components were recorded, of which thiryt-three cross-reacted with mycobacterium tuberculosis, twenty-five with m. av ... | 1979 | 106465 |
| pericarditis due to mycobacterium tuberculosis and mycobacterium fortuitum: a case report. | in this case study, pericarditis results from mycobacterium tuberculosis and mycobacterium fortuitum. both organisms were isolated from three different clinical specimens: a pericardial fluid, pericardium, and a thoracentesis fluid. a mixed mycobacterial culture was initially suspected upon examining ziehl-neelsen stained smears prepared from the primary cultures following seven to ten days of incubation. dilutions and subcultures were subsequently performed, confirming the presence of two diffe ... | 1979 | 106725 |
| [sputum positive conversion among retreatment cases with pulmonary tuberculosis converted to negative by the use of rifampicin (author's transl)]. | | 1979 | 107360 |
| [effect of amikacin on experimental tuberculosis of mice (author's transl)]. | | 1979 | 107361 |
| [short course chemotherapy for pulmonary tuberculosis with duration for 6 months after sputum negative conversion. (report 1)--report of the 19--20th a series of controlled trial of chemotherapy--(author's transl)]. | | 1979 | 107362 |
| [epidemiological and clinical aspects of drug-resistant tubercle bacilli in children treated in the years 1961--1976]. | | 1979 | 107515 |
| benign presentation of tuberculous meningitis. | | 1979 | 107992 |
| immunosuppression by mycobacterial arabinomannan. | | 1979 | 108041 |
| thrombocyte migration and the release of thrombocyte inhibitory factor (thrif) by t and b cells in the chicken. | the elaboration of various inhibitory factors by sensitized lymphocytes has been reported for both mammals and birds. until recently, the ability of the b cell to elaborate these had been questioned by a number of investigators. we have demonstrated the release of a lymphocyte inhibitory factor from the avian thymus and bursal lymphocyte. the avian thrombocyte is active in haemostasis as well as being a phagocytic cell. we have demonstrated that the ability of the thrombocyte to migrate, signifi ... | 1979 | 108206 |
| tuberculosis of the mandible presenting as 'lumpy jaw'. | | 1979 | 108413 |
| [bactericidal effect of rifampicin on resting tubercle bacilli in vitro (author's transl)]. | | 1979 | 108446 |
| [tuberculosis and changes in the tissue lipids]. | | 1979 | 108447 |
| [effect of carbon dioxide on the inoculability of mycobacterium tuberculosis from pathological material]. | | 1979 | 108674 |
| induction kinetics of delayed hypersensitivity towards mycobacterium tuberculosis and m. avium: analysis of cross-reactions elicited by ppd-tuberculin and ppd-b. | | 1978 | 108772 |
| miliary tuberculosis in children. clinical and laboratory manifestation in 19 patients. | the clinical course of 19 children with miliary tuberculosis was studied. complaints were nonspecific and included fever, anorexia, weight loss, and night sweats. although all but one child had a miliary infiltrate visible on the chest roentgenogram, only 13 had a positive reaction to the purified protein derivative of the tuberculin test at admission to the hospital. outcome was excellent unless the child also had tuberculous meningitis or was in a far advanced state of the disease. miliary tub ... | 1979 | 108996 |
| the booster phenomenon in serial tuberculin testing. | to determine the frequency, magnitude, and causes of the booster phenomenon in tuberculin testing, a total of 1,478 employees from 10 hospitals throughout the united states received sequential intradermal tests using ppd-t. in addition, approximately 70 per cent were initially tested with ppd-g. boosting was found in all age groups tested, but increased with age. it occurred as soon as one week after an initial tuberculin test, but rarely before that time. the boosted reactions were apparently c ... | 1979 | 109023 |
| primary drug resistance in children. drug susceptibility of strains of mycobacterium tuberculosis isolated from children during the years 1973 through 1977 at the kings county hospital center of brooklyn. | a continuing study of the frequency of primary drug resistance among children treated at the kings county hospital center of brooklyn during the years 1973 through 1977 showed a high incidence of primary drug resistance to isoniazid (8.8 per cent) and to streptomycin (12.3 per cent). in contrast, there were no strains resistant to cycloserine, viomycin, ethambutol, or rifampin, and only one of 57 strains (1.8 per cent) was resistant to ethionamide, and one (1.8 per cent) was resistant to para-am ... | 1979 | 109024 |
| [criteria of resistance of some antibiotics and chemotherapeutics for strains of mycobacterium tuberculosis isolated in czechoslovakia. cycloserin, ethionamide, pyrazinamide, rifampicin, and ethambutol (author's transl)]. | | 1979 | 109213 |
| biochemical changes in avian tissues during infection. | major sources of error in studies of diet--infectious disease interactions relate to failure 1) to define the stage of a disease cycle; and 2) to determine the extent of disease involvement at time of sampling. the former can be determined from clinical and biochemical observations from time of inoculation to recovery or mortality; the latter can be calculated from indexes obtained from histological preparations, changes in body temperatures, and other clinical symptoms, including weight loss an ... | 1979 | 109321 |
| demonstration of tuberculostearic acid in sputum from patients with pulmonary tuberculosis by selected ion monitoring. | selected ion monitoring was used to detect tuberculostearic acid (10-methyloctadecanoic acid) in sputum from patients with pulmonary tuberculosis. the specimens were autoclaved, lyophilized, extracted, and methanolysed before being subjected to thin-layer chromatography and injected into the gas chromatograph/mass spectrometer. tuberculostearic acid could be detected in five of six tuberculous sputum specimens containing acid-fast rods detectable by light microscopy of ziehl-neelsen stained smea ... | 1979 | 109465 |
| [effect of various disinfectants (phenol derivatives, quaternary ammonium compounds, aldehydes and chloramine) on human type tubercle bacilli sensitive and resistant to antibacillary drugs]. | | 1979 | 109709 |
| confusion of legionella pneumophila and mycobacterium tuberculosis. | | 1979 | 109752 |
| fatal tuberculosis in young children. | three young children with advanced cavitary pulmonary tuberculosis died between 1974 and 1978. two of the patients had tuberculous meningitis as well. all diagnoses were verified at autopsy; however, all tuberculin skin tests were negative. these instances emphasize the difficulty of establishing the diagnosis of tuberculosis in young children. tuberculosis should be considered in the differential diagnosis of cavitary chest disease in young children, even those with negative tuberculin skin tes ... | 1979 | 109806 |
| [lymphocyte transformation test in patients with active tuberculosis and in healthy subjects frequently exposed to m tuberculosis]. | | 1979 | 109821 |
| direct migration inhibition test with leukocytes as indicator of mycobacterial antigens in the human body. | in 32 patients with newly detected pulmonary tuberculosis positive on smear and culture, included in a controlled clinical trial, a significant correlation between diminishing inhibition of leukocyte migration (induced by ppd) and reduction of mycobacterial population in the sputum during the course of chemotherapy has been demonstrated. the changes of mycobacterial population in the host have been assessed in two ways: an indirect assessment was made from the time taken to achieve sputum smear ... | 1979 | 109977 |
| further studies of mycobacteriophage 33d (warsaw) for differentiation of bcg from m. bovis and m. tubeculosis. | mycobacteriophage 33d (warsaw) was used to differentiate bacille calmette-guerin (bcg) strains from m. bovis and m. tuberculosis. known strains as well as clinical strains of bcg were used in the study. single plaque isolations and adsorption studies demonstrated that phage 33d (warsaw) did not adsorb to bcg cultures. | 1979 | 109978 |
| the value of the routine guinea-pig test. | | 1979 | 109980 |
| [sensitivity of mycobacterium tuberculosis to antitubercular agents]. | | 1979 | 109991 |
| [incidence of drug resistance of mycobacterium tuberculosis]. | | 1979 | 109992 |
| pulmonary manifestations of mycobacterium intracellularis. | pulmonary manifestations in 114 patients with at least two sputum cultures positive for m. intracellularis, no history of any kind of tuberculosis, and not other potential pathogen are described. even with these stringent diagnostic criteria, seven patients had normal chest radiographs and another seven had reticulonodular-appearing disease without a definite focus of infection. in the other 100 patients, 92% had infiltrates in the apical and/or posterior segments of the upper lobes, and 88% had ... | 1979 | 110071 |
| u.s. public health service cooperative trial of three rifampin-isoniazid regimens in treatment of pulmonary tuberculosis. | a total of 822 patients with newly diagnosed pulmonary tuberculosis were assigned randomly to one of 3 daily rifampin-isoniazid (rif-inh) regimens: 450, 600, or 750 mg of rif in combination with 300 mg of inh. after an initial 20 weeks of therapy with rif-inh, patients recieved 300 mg of inh and 15 mg of ethambutol (emb) per kg of body weight for either 12 or 18 months after their sputum cultures became negative. the rate of bacteriologic conversion of sputum among the 3 rif-inh regimens was com ... | 1979 | 110184 |
| [tuberculosis in patients deceased of renal insufficiency in a long-term hemodialysis program]. | eight cases of tuberculosis were seen in a series of patients dying of renal insufficiency after having been subjected to a long-term haemodialysis. in 5 cases mycobacterium tuberculosis was successfully cultivated (4 were typed as human, 1 as bovine). in 5 cases the disease affected mainly the lymph nodes, not the lungs. in 3 of these a prevalence of abscessing specific granulomas with the presence of leucocytes was noted on microscopical examination. the findings have been regarded as possibly ... | 1979 | 110471 |
| "routine."--a practice to be abjured. | | 1979 | 110537 |
| tuberculosis in oriental immigrants: a study in military dependents. | tuberculosis in oriental immigrants is likely to be resistant to therapy with certain drugs. in 73 military dependents with positive cultures for tuberculosis who immigrated from six asian countries, the tuberculosis was found to be resistant to isoniazid in 58 percent (42 patients), to streptomycin in 36 percent (26 patients), to p-amino-salicylic acid in 14 percent (ten patients), to rifampin in 7 percent (five patients), and to ethambutol in 7 percent (five patients). despite the presence of ... | 1979 | 110538 |
| diagnosis of tuberculosis: routine cultures of bronchial washings are not indicated. | during a five-year period, cultures of bronchial washings for mycobacterium tuberculosis were obtained almost routinely (859 of 1,012 bronchoscopic examinations.). this practice proved costly, and the diagnostic yield was extremely low. only three cases were diagnosed solely by this method (0.35 percent). five other cases were false-positive. additionally, 39 patients with known active pulmonary tuberculosis had false-negative cultures of bronchial washings; 13 of these 39 patients were receivin ... | 1979 | 110539 |
| immunobiology and species distribution of mycobacterium tuberculosis antigen 5. | the immunobiology and mycobacterial species distribution of immunoabsorbent affinity chromatography-purified mycobacterium tuberculosis antigen 5 have been studied. in delayed hypersensitivity skin tests, antigen 5 was nearly equipotent with tuberculin-purified protein derivative in sensitized guinea pigs. in vitro, antigen 5 was capable of stimulating the production of migration inhibitory factor by cultured lymphocytes from sensitized guinea pigs and humans. antigen 5 stimulated thymidine inco ... | 1979 | 110696 |
| antigenic differences between extracts of actively replicating and synchronized resting cells of mycobacterium tuberculosis. | protein extracts were prepared from aerobically replicating cells of mycobacterium tuberculosis and from synchronized non-replicating cells derived from the sediments of non-agitated cultures. although both preparations share a number of antigens, the extracts of the non-replicating cells also contain antigenic components that are not shared by the replicating cells, and which can be isolated and visualized by immunoaffinity chromatography and immunoelectrophoretic techniques. | 1979 | 110697 |
| three types of mycolic acid from mycobacterium tuberculosis brévanne: implications for structure-function relationships in pathogenesis. | saponification of the chloroform-soluble wax from mycobacterium tuberculosis brévanne led to the isolation of three classes of mycolic acid containing characteristic functional groups along the methylene backbone: type alpha (two cyclopropane rings); type beta (methoxyl, methyl, and cyclopropane); and type gamma (ketone, methyl, and cyclopropane). the structures of these acids were elucidated principally by mass spectrometry. the high mass region of the keto mycolate is presented showing the mer ... | 1979 | 110779 |
| immunoregulation in infection caused by mycobacterium tuberculosis: the presence of suppressor monocytes and the alteration of subpopulations of t lymphocytes. | this study was designed to characterize qualitative and quantitative alterations, occurring before and during chemotherapy, in the mononuclear cells of patients with infections caused by mycobacterium tuberculosis. a hemolytic plaque-forming (pfc) assay indicated that the production of antibody to sheep red blood cells by pokeweed mitogen (pwm)-stimulated lymphocytes was suppressed in treated and untreated patients as compared with that in normal adult donors (p less than 0.001). the removal of ... | 1979 | 110887 |
| brain tuberculoma. diagnosis and treatment. | | 1979 | 110891 |
| tuberculosis of the cns presenting as mass lesions. | | 1979 | 111206 |
| diagnosis and management of tuberculosis. | | 1979 | 111269 |
| tuberculous cervical lymphadenitis. | | 1979 | 111794 |