| [microflora of the inflammatory erosive areas of the esophagus in esophagitis patients]. | seven patients with erosive esophagitis and reflux esophagitis were examined. in cases of inflammatory erosive phenomena staphylococci, micrococcus luteus, candida, bacteria of the genera pseudomonas, veilonella, klebsiella and other bacteria of the family enterobacteriaceae, as well as helicobacter pylori were detected in different frequency. in most cases concentrations of microorganisms were 4.07-5.39 ig cfu/g. isolated microorganisms producing different pathogenicity enzymes--hemolysin (stre ... | 2002 | 12043159 |
| [hepatic abscess caused by streptococcus iintermedius as first manifestation of renal carcinoma]. | | 2002 | 12073672 |
| distribution of mef(a) in gram-positive bacteria from healthy portuguese children. | we screened 615 gram-positive isolates from 150 healthy children for the presence of the erm(a), erm(b), erm(c), erm(f), and mef(a) genes. the mef(a) genes were found in 20 (9%) of the macrolide-resistant isolates, including enterococcus spp., staphylococcus spp., and streptococcus spp. sixteen of the 19 gram-positive isolates tested carried the other seven open reading frames (orfs) described in tn1207.1, a genetic element carrying mef(a) recently described in streptococcus pneumoniae. the thre ... | 2002 | 12121926 |
| haemophilus segnis polymicrobial and monomicrobial bacteraemia identified by 16s ribosomal rna gene sequencing. | this paper reports a case of haemophilus segnis polymicrobial bacteraemia and a case of h. segnis monomicrobial bacteraemia identified by 16s ribosomal rna gene sequencing. in the first case, a gram-negative aerobic coccobacillus was isolated with streptococcus intermedius and s. sanguis from the blood culture of a 32-year-old intravenous drug addict with left thoracic empyema. in the second case, a gram-negative aerobic coccobacillus was isolated from the blood culture of an 82-year-old woman w ... | 2002 | 12171293 |
| groesl sequence determination, phylogenetic analysis, and species differentiation for viridans group streptococci. | the full-length sequences of the groesl genes (also known as cpn10/60) of streptococcus anginosus, streptococcus constellatus, streptococcus gordonii, and streptococcus sanguis and the near full-length sequence of the groesl genes of streptococcus intermedius, streptococcus bovis, streptococcus mitis, streptococcus mutans, streptococcus oralis, and streptococcus salivarius were determined. the lengths of the groes genes from the 10 species listed above ranged from 282 to 288 bp, and the full-len ... | 2002 | 12202549 |
| cloning and expression of hyaluronate lyase genes of streptococcus intermedius and streptococcus constellatus subsp. constellatus(1). | hyaluronate lyase (haase) genes of streptococcus intermedius and streptococcus constellatus subsp. constellatus were isolated. in s. constellatus subsp. constellatus, the deduced amino acid sequence of haase was most similar to that of s. intermedius (68%), whereas the enzyme of s. intermedius was most similar to that of s. pneumoniae (72%). upstream of the haase gene on the opposite strands, an open reading frame of a putative glutathione peroxidase started in s. intermedius, and this arrangeme ... | 2003 | 12594036 |
| [early diagnosis of bacterial brain abscesses: interest of diffusion-weighted mri]. | three cases of bacterial brain abscesses, in immunocompetent patients, are reported. in all these cases, the diffusion-weighted magnetic resonance (mri) with apparent diffusion coefficient (adc) map has permitted an early diagnosis and a rapid treatment. this emergency mri showed in the three cases a low signal on ti-weighted images, a high signal on t2-weighted and echo-planar images, and a decrease of adc (0.36- 0.49 x 10(-3) mm2/s). so, this new mri technique provides an available and rapid e ... | 2003 | 12773871 |
| deep neck infection: a present-day complication. a retrospective review of 83 cases (1998-2001). | deep neck infections are less and less frequent today than in the past. nevertheless, their complications are often life-threatening. the present study reviews the experience of the department of otolaryngology and head and neck surgery of padua with deep neck infections during the period from 1998 to 2001. eighty-three patients (55 males and 28 females) were retrospectively considered. the site of origin of deep neck infection was identified in 76 patients (91%). the most common cause was denta ... | 2003 | 12774234 |
| additive antimicrobial activity of calcium hydroxide and chlorhexidine on common endodontic bacterial pathogens. | it is an established procedure to use calcium hydroxide [ca(oh)2] as a therapeutic component to achieve sterilization of infected root canals. unfortunately, some bacterial species are relatively resistant to ca(oh)2 and are therefore associated with treatment failures. the objective of this study was to identify combinations of substances that improve antimicrobial activity. ca(oh)2 was used as a suspension or as a component of gutta-percha points. efficacy of killing was compared for (a) ca(oh ... | 2003 | 12775007 |
| subgingival microbiota levels and their associations with periodontal status at the sampled sites in an adult sudanese population using miswak or toothbrush regularly. | little information is available on the effect of miswak use on gingival microbiota. we assessed levels of 28 oral bacteria in subgingival plaque of adult sudanese miswak (n = 38) and toothbrush users (n = 36) age range 20-53 years (mean 34.6 years) to study associations between these bacteria, oral hygiene method, and periodontal status at the sampled sites. a pooled subgingival plaque sample from 6 probing sites of 1 selected tooth in each jaw was obtained from each subject. whole genomic dna p ... | 2003 | 12790510 |
| genotyping by amplified fragment length polymorphism analysis reveals persistence and recurrence of infection with streptococcus anginosus group organisms. | streptococcus anginosus, streptococcus constellatus, and streptococcus intermedius, commonly referred to as the streptococcus anginosus group (sag), are commensal organisms known for their propensity to cause purulent infections which are difficult to eradicate. in this study, we determined the genetic similarities between sag isolates consecutively recovered from single patients to assess the duration of infection or colonization. a total of 97 sag isolates recovered from 30 patients were inclu ... | 2003 | 12843013 |
| pediatric epiglottitis caused by group g beta-hemolytic streptococcus. | | 2003 | 14515840 |
| the acid-tolerant microbiota associated with plaque from initial caries and healthy tooth surfaces. | the intent of this study was to compare the inherent acid tolerance of bacteria in samples of dental plaque from tooth sites in subjects with and without initial caries. plaque was collected from approximal surfaces showing early enamel caries and from healthy tooth surfaces in the same subjects, as well as from enamel surfaces of caries-free individuals. in addition to plating on blood agar, the plaque samples were plated directly on non-selective solid agar medium buffered to ph 7.0, 6.0, 5.5, ... | 2003 | 14571116 |
| [bacteremia, endocarditis and abscess due to streptococcus intermedius]. | | 2003 | 14624664 |
| culture-independent identification of pathogenic bacteria and polymicrobial infections in the genitourinary tract of renal transplant recipients. | renal transplant recipients are predisposed to urinary tract infections caused by both common uropathogens and opportunistic bacteria resulting frequently in significant polymicrobial infections. in this study, a culture-independent 16s rrna-based approach was established to identify unusual, fastidious, or anaerobic bacteria and to investigate bacterial diversity in urinary tract specimens. similarly sized amplicons encompassing the v6 to v8 region of the 16s rrna were analyzed with denaturing ... | 2003 | 14662931 |
| purification of saliva agglutinin of streptococcus intermedius and its association with bacterial aggregation and adherence. | streptococcus intermedius strain 1208-1 cells were aggregated in the presence of saliva. the saliva agglutinin was purified by centrifugation, filtration, and gel filtration. sds-page analyses indicated that the purified agglutinin consisted of two high-molecular-mass proteins. aggregation was dependent on calcium over ph 5.5, with 1 mm being the most effective concentration. boiling inactivated purified agglutinin. s. intermedius strain 3 and streptococcus mutans strain 1 were aggregated in the ... | 2004 | 14676988 |
| platelet responses and anaphylaxis-like shock induced in mice by intravenous injection of whole cells of oral streptococci. | intravenous injection of lyophilized whole cells of various oral streptococcal strains into muramyldipeptide (mdp)-primed c3h/hen mice induces rapid anaphylactoid shock. here we examined the mechanism underlying this shock. in non-primed mice, streptococcus intermedius k-213k (sik213) and streptococcus constellatus t21 (sct21) produced little or no sign of shock. in mdp-primed mice, sik213 caused lethal shock, while sct21 only had a weak effect. sik213 induced decreases in blood platelets and 5- ... | 2004 | 14678471 |
| crystallization and preliminary x-ray analysis of the human-specific toxin intermedilysin. | intermedilysin is a human-specific toxin from streptococcus intermedius, which is part of normal human oral flora. the bacterium is an opportunistic pathogen with a tendency for deep-seated infection in the brain and liver. intermedilysin belongs to the cholesterol-dependent cytolysin (cdcs) family of toxins, which have been identified in several different bacteria including the serious human pathogens s. pneumoniae and clostridium perfringens. intermedilysin, however, is the only member that sh ... | 2004 | 14747721 |
| distribution and characterization of hemolytic activity by an oral anaerobe from the streptococcus milleri group. | some oral anaerobes from the streptococcus milleri strain group were found to secrete human specific hemolytic toxin, which was detected when bacteria were cultured in todd-hewitt broth and brain heart infusion broth. the toxin elicited by the streptococcus intermedius strain was partially fractionated by ammonium sulfate precipitation. preincubation with glutathione or cysteine showed significant inhibiting effects; however, no effects were seen with dithiothreitol or beta-mercaptoethanol, and ... | 2004 | 14871356 |
| [septic abscess-forming pneumonia with osseous and hepatic involvement caused by streptococcus intermedius]. | | 2004 | 15026958 |
| identification of the anginosus group within the genus streptococcus using polymerase chain reaction. | the aim of this study was to establish an identification method for the anginosus group within the genus streptococcus by polymerase chain reaction (pcr). using a primer pair based on the group-specific sequences of penicillin-binding protein 2b (pbp2b) gene, a 275-bp fragment was amplified from each species in the group but no size-matched products were obtained in other streptococci. further identification in the species or subspecies level was possible by a multiplex pcr with primers for the ... | 2004 | 15043873 |
| human salivary aggregation in streptococcus intermedius type g strains: relationship with iga. | bacterial aggregation is an important step in elimination from the human body to protect against infection. streptococcus intermedius k1k aggregates in human saliva. in this study, the salivary agglutinin was identified. the aggregation level was very strong in sonic-treated saliva and 1-microm filtrate. preincubation of human saliva with anti-human alpha chain serum or anti-human whole saliva serum completely inhibited aggregation, but preincubation with anti-human micro chain serum or anti-fc ... | 2004 | 15145453 |
| characterization of tn916s, a tn916-like element containing the tetracycline resistance determinant tet(s). | we have characterized a transferable tetracycline resistance (tcr) element from a streptococcus intermedius isolate. the gene responsible for this resistance was identified by pcr and southern hybridization as tet(s). furthermore, the genetic support for this determinant was shown to be a conjugative transposon closely related to tn916. this element has been designated tn916s. | 2004 | 15205444 |
| isolation and some properties of fimbriae of oral streptococcus intermedius. | streptococcus intermedius 1208-1 carried linear fiber-like fimbriae that extended radially from the cell surface. the fimbriae were isolated by pipetting and sonication and were purified by ammonium sulfate precipitation followed by a column chromatography series. heat treatment in the presence of sodium dodecyl sulfate resulted in the dissociation into smaller molecules. rabbit antiserum raised against the purified protein reacted with fimbriae on the surface of bacteria under immunogold staini ... | 2004 | 15297932 |
| biofilm mode of growth of streptococcus intermedius favored by a competence-stimulating signaling peptide. | gram-positive and gram-negative bacteria use quorum sensing to coordinate population behavior. in several streptococci, quorum sensing mediated by competence-stimulating peptides (csp) is associated with development of competence for transformation. we show here that a synthetic csp favored the biofilm mode of growth of streptococcus intermedius without affecting the rate of culture growth. | 2004 | 15342606 |
| the human-specific action of intermedilysin, a homolog of streptolysin o, is dictated by domain 4 of the protein. | intermedilysin is a pore-forming cytolysin belonging to the streptolysin o gene family known as the 'cholesterol-binding/dependent cytolysins' and is unique within the family in that it is highly humanspecific. this specificity suggests interaction with a component of human cells other than cholesterol, the proposed receptor for the other toxins of the gene family. indeed, intermedilysin showed no significant degree of affinity to free or liposome-embedded cholesterol. characterization of interm ... | 2004 | 15383705 |
| molecular analysis of age-related changes of streptococcus anginosus group and streptococcus mitis in saliva. | the purpose of this study was to survey the prevalence of streptococcal species, especially streptococcus anginosus (which has been reported to be associated with cancer in the upper digestive tract), streptococcus constellatus, and streptococcus intermedius in the saliva of different age groups. a sequence analysis of 16s rdna was performed and dna quantified using real-time polymerase chain reaction. the s. anginosus level increased with age, whereas the levels of s. constellatus and s. interm ... | 2004 | 15491464 |
| streptococcus sinensis may react with lancefield group f antiserum. | lancefield group f streptococci have been found almost exclusively as members of the 'streptococcus milleri' group, although they have been reported very occasionally in some other streptococcal species. among 302 patients with bacteraemia caused by viridans streptococci over a 6-year period, three cases were caused by streptococcus sinensis (type strain hku4t, hku5 and hku6). all three patients had infective endocarditis complicating their underlying chronic rheumatic heart diseases. gene seque ... | 2004 | 15496384 |
| brain abscess after milk tooth self-extraction. | brain abscesses are rare, especially in children, but they can be life-threatening infections. to date, dental pathology has been linked to only a small number of brain abscesses. to our best knowledge this is the first reported case of a brain abscess following self-extraction of a milk tooth. we are reporting on a 12-year-old previously healthy boy who developed a brain abscess in the vicinity of the left precentral gyrus. clinical examination prior to surgery showed a severe right hemiparesis ... | 2004 | 15506321 |
| subacute bacterial endocarditis associated with upper endoscopy. | transient bacteremia associated with various endoscopic procedures is a well-documented phenomenon. clinically important bacteremias are very rarely seen, however, this malady has significant morbidity in susceptible patients with valvular heart disease, liver cirrhosis, malignancy and immune deficiency. this bacteremia is a complication that is generally observed secondary to upper endoscopy and other associated invasive procedures in at risk patients, and the more serious manifestations includ ... | 2004 | 15515208 |
| structural analysis of human specific cytolysin intermedilysin aiming application to cancer immunotherapy. | intermedilysin (ily) is a human specific cytolysin secreted by streptococcus intermedius. in the present study, we performed molecular modeling of ily and cholesterol-dependent cytolysins (cdcs) (pneumolysin, ply; listeriolysin o, llo; streptolysin o, slo; alveolysin, alv; suilysin, sly; pyolysin, plo) to compare the membrane binding domains including the undecapeptide (11mer) region which is thought to be necessary for the cytolytic activity of cdcs. | 2004 | 15515430 |
| a cell membrane modification technique using domain 4 of intermedilysin for immunotherapy against cancer. | rapid cell membrane modification techniques are currently being sought in order to develop gene therapy and cellular immunotherapy modalities against cancer and other diseases. we developed a novel technique using the non-toxic portion of intermedilysin, a streptolysin o family cytolysin with a high affinity for human cell membranes, as a cell membrane adaptor module. domain 4 recombinants of intermedilysin with linker sites at the n-terminus were designed. these modules are able to bind tightly ... | 2004 | 15515433 |
| human cd59 is a receptor for the cholesterol-dependent cytolysin intermedilysin. | cholesterol is believed to serve as the common receptor for the cholesterol-dependent cytolysins (cdcs). one member of this toxin family, streptococcus intermedius intermedilysin (ily), exhibits a narrow spectrum of cellular specificity that is seemingly inconsistent with this premise. we show here that ily, via its domain 4 structure, binds to the glycosyl-phosphatidylinositol-linked membrane protein human cd59 (hucd59). cd59 is an inhibitor of the membrane attack complex of human complement. i ... | 2004 | 15543155 |
| single species biofilm-forming ability of root canal isolates on gutta-percha points. | the participation of bacterial biofilms in the over-filled gutta-percha points associated with refractory periapical periodontitis has recently been reported. this study investigated the initial biofilm-forming ability of root canal isolates (enterococcus faecalis, streptococcus sanguis, strep. intermedius, strep. pyogenes, staphylococcus aureus, fusobacterium nucleatum, propionibacterium acnes, porphyromonas gingivalis and prevotella intermedia) on gutta-percha points in vitro. each bacterial s ... | 2004 | 15560836 |
| a bacterial big-mac attack. | | 2004 | 15578056 |
| effect of ph modified edta solution to the properties of dentin. | the purpose of this study was to evaluate the influence of smear layer removal with 3% edta solution (ph of 9.0) on the dentin in terms of the permeability of root canal disinfectants into the dentin, wetting by endodontic sealer, and adhesive strength of the sealer. three types of disinfectant (formalin cresol, phenol, and calcium hydroxide) and 4 types of endodontic sealers (included eugenol, non-eugenol, polycarboxylic acid, and resin) were used. the contact angle between endodontic sealer so ... | 2005 | 15614006 |
| insights into the action of the superfamily of cholesterol-dependent cytolysins from studies of intermedilysin. | the cholesterol-dependent cytolysins (cdcs), a superfamily of pore-forming toxins, are characterized by a conserved undecapeptide motif that is believed to be critical for membrane recognition by means of cholesterol. intermedilysin (ily), an unusual member of the cdcs, exhibits specificity for human cells and contains nonconservative substitutions in the motif. we show that the cellular specificity of ily is based on its ability to specifically bind to human cells and does not involve some othe ... | 2005 | 15637162 |
| quorum sensing in streptococcal biofilm formation. | bacteria in their natural ecosystems preferentially grow as polysaccharide-encased biofilms attached to surfaces. although quorum-sensing (qs) systems directing the 'biofilm phenotype' have been extensively described in gram-negative bacteria, there is little understanding of the importance of these systems in gram-positive biofilm formation. streptococci are a diverse group of gram-positive bacteria that colonize epithelial, mucosal and tooth surfaces of humans. in several streptococci, compete ... | 2005 | 15639624 |
| intermedilysin release by streptococcus intermedius: effects of various antibacterial drugs at sub-mic levels. | intermedilysin is a cytolytic toxin produced by streptococcus intermedius, a pathogen of humans. in vitro studies showed that exposure of s. intermedius to sub-minimum inhibitory concentration (mic) levels (1/2 mic) of protein-inhibiting antibiotics and nucleic acid-inhibiting antibiotics decreased intermedilysin release by s. intermedius. the most potent antibiotic was clindamycin. on the other hand, exposure to cell wall-inhibiting antibiotics generally showed insignificant changes in intermed ... | 2005 | 15686838 |
| periodontal infections and pre-term low birth weight: a case-control study. | pre-term delivery of low-birth-weight infants [pre-term low birth weight (plbw)] remains a significant public health issue and a major cause of neonatal death and long-term health problems. there is a growing consensus that infections remote from fetal-placental unit may influence plbw infants. recent studies have suggested that maternal periodontal disease may be an independent risk factor for plbw. the purpose of the present study was to evaluate the possible link between periodontal infection ... | 2005 | 15691348 |
| differential binding specificities of oral streptococcal antigen i/ii family adhesins for human or bacterial ligands. | the antigen i/ii (agi/ii) family polypeptides, ranging from 1310 to 1653 amino acid (aa) residues, are cell wall anchored adhesins expressed by most indigenous species of oral streptococci. the polypeptides interact with a wide range of host molecules, in particular salivary agglutinin glycoprotein (sag or gp340), and with ligands on other oral bacteria. to determine the receptor recognition properties of six different agi/ii family polypeptides from strains of streptococcus gordonii, streptococ ... | 2005 | 15720563 |
| effect of khat chewing on 14 selected periodontal bacteria in sub- and supragingival plaque of a young male population. | the habit of chewing khat (catha edulis) for its amphetamine-like effects is highly prevalent in yemen and east africa, and has expanded to western countries. the purpose of this study was to estimate and compare the prevalence and levels of 14 periodontal bacteria in gingival plaque of khat chewers and khat nonchewers, as well as of khat chewing sides and khat nonchewing sides. | 2005 | 15836514 |
| phenotypic and genotypic selection of microbiota surviving under dental restorations. | the effects of sealing infected carious dentine below dental restorations on the phenotypic and genotypic diversity of the surviving microbiota was investigated. it was hypothesized that the microbiota would be subject to nutrient limitation or nutrient simplification, as it would no longer have access to dietary components or salivary secretion for growth. the available nutrients would be limited primarily to serum proteins passing from the pulp through the patent dentinal tubules to the infect ... | 2005 | 15870335 |
| tobacco smoking and periodontal microflora in a saudi arabian population. | to explore the subgingival periodontal microflora in a saudi arabian population with a special focus on its relationship with various smoking habits. | 2005 | 15882210 |
| bacterial colonization on different suture materials--a potential risk for intraoral dentoalveolar surgery. | in this in vivo and in vitro study on resorbable (monocryl and nonresorbable (deknalon) monofilament sutures used in intraoral dentoalveolar surgery the bacterial colonization was compared. for the in vivo study the sutures were applied in 11 patients during dental surgery. eight days postoperative the sutures were removed and the adhered bacteria were isolated and identified by biochemistry, morphology, antibiotic susceptibility, and gas chromatography. the colonization was studied by scanning ... | 2005 | 15889436 |
| experimental abscess formation caused by human dental plaque. | human dental plaque consists of a wide variety of microorganisms, some of which are believed to cause systemic infections, including abscesses, at various sites in the body. to confirm this hypothesis experimentally, we examined the abscess-forming ability of native dental plaque in mice, the microbial features of the infectious locus produced by the plaque, and the anti-phagocytic property of microbial isolates. aliquots of a suspension of supragingival dental plaque containing 6 x 10(6) colony ... | 2005 | 15905601 |
| [brain abscess caused by eikenella corrodens and streptococcus intermedius associated with bowel carcinoid tumour]. | | 2005 | 15989847 |
| [a very purulent lumbar puncture]. | | 2005 | 15996573 |
| [meningitis and brain abscess caused by streptococcus intermedius in a patient infected with hiv-1]. | streptococcus milleri group have been recognized as an important pathogens for abscess formation in various organs. streptococci other than streptococcus pneumoniae are a rare cause of bacterial meningitis in adults and can be associated with the presence of an undiagnosed brain abscess. brain abscess is a focal collection within the brain parenchyma which can arise as a complication of a variety of infections. the most common etiologic organisms in clinical series have been microaerophilic stre ... | 2005 | 16011407 |
| [primary left subphrenic abscess due to streptococcus intermedias]. | | 2005 | 16013102 |
| intermedilysin is essential for the invasion of hepatoma hepg2 cells by streptococcus intermedius. | streptococcus intermedius causes endogenous infections leading to abscesses. this species produces intermedilysin (ily), a human-specific cytolysin. because of the significant correlation between higher ily production levels by s. intermedius and deep-seated abscesses, we constructed ily knockout mutant uns38 b3 and complementation strain uns38 b3r1 in order to investigate the role of ily in deep-seated infections. strain uns38 reduced the viability of human liver cell line hepg2 at infection bu ... | 2005 | 16034212 |
| clinical, phenotypic, and genotypic evidence for streptococcus sinensis as the common ancestor of anginosus and mitis groups of streptococci. | in 2002, we reported the discovery of a novel species of viridans streptococcus, streptococcus sinensis. recently, we reported the isolation of two more strains of s. sinensis. clinically, s. sinensis is a definite cause of infective endocarditis, a characteristic mainly pertaining to the mitis group of streptococci. phenotypically, two of the three s. sinensis isolates were lancefield group f, a characteristic of the anginosus group. however, none of the three strains possess the caramel smell ... | 2006 | 16216437 |
| infective endocarditis complicating rituximab (anti-cd20 monoclonal antibody) treatment in an sle patient with a past history of libman-sacks endocarditis: a case for antibiotic prophylaxis? | we report a 54 year old female whose successful treatment of cerebral lupus with rituximab was complicated by the development of streptococcus intermedius, on valves damaged by libman-sacks endocarditis more than 20 years previously. | 2006 | 16222410 |
| estimation of salivary bacteria capable of inhibiting and stimulating streptococcus mutans and its correlation to dental caries and untreated carious teeth. | bacteriocins are bacteriocidal proteinaceous molecules produced by the gram-positive bacteria not active against the produced strain. many investigations have revealed that certain bacteria using antibacterial or the inhibitory substance inhibit some other bacteria. a study was conducted in a group of 60 children to ascertain whether any correlation exists between the proportion of salivary bacteria inhibiting and stimulating streptococcus mutans and the oral health indices (dmft, deft and commu ... | 2005 | 16224131 |
| predominant presence of streptococcus anginosus in the saliva of alcoholics. | chronic alcohol consumption is known to be a major risk factor for cancers of the upper aerodigestive tract. the incidence of esophageal cancer (4.4%) in alcoholics is reported to be much higher than that in the japanese population as a whole (0.0001%). this suggests the presence of specific factors in chronic alcohol consumption-related carcinogenesis. recently, data showing a significant correlation between streptococcus anginosus and carcinogenesis in the upper aerodigestive tract have been r ... | 2005 | 16238596 |
| involvement of antigen i/ii surface proteins in streptococcus mutans and streptococcus intermedius biofilm formation. | dental diseases are caused by microorganisms organized in biofilms. streptococcus mutans and streptococcus intermedius are commensals of the human oral cavity. s. mutans is associated with caries, whereas s. intermedius is associated with purulent infections. oral streptococci including s. mutants and s. intermedius express a family of surface proteins termed antigen i/ii (ag i/ii). ag i/ii is implicated in adhesion; however, its role in biofilm formation has not yet been investigated. | 2005 | 16238597 |
| antibacterial action of photoactivated disinfection {pad} used on endodontic bacteria in planktonic suspension and in artificial and human root canals. | to measure antibacterial action of photoactivated disinfection (pad) on endodontic bacteria in planktonic suspension and root canals. methods: four bacteria, fusobacterium nucleatum,peptostreptococcus micros, prevotella intermedia and streptococcus intermedius, were tested in suspension. after mixing equal volumes of tolonium chloride and bacterial suspension for 60s, each 200 microl of concentration (>10(6)cfu ml(-1)) was irradiated with light at 633+/-2 nm. each energy dose/tolonium chloride c ... | 2006 | 16239058 |
| orbital abscess after extraction of a maxillary wisdom tooth. | a 21-year-old patient with orbital abscess and vision loss left after wisdom-tooth extraction is presented. | 2007 | 16310905 |
| a new checkerboard panel for testing bacterial markers in periodontal disease. | various microbiological methods have been used for testing bacterial markers for periodontitis and periodontal disease progression. most studies have used only a limited number of well recognized bacterial species. the purpose of the present study was to evaluate the association of 13 more recently identified bacterial species in a new panel in comparison with 12 previously more recognized periodontotopathogens ('old panel') using the 'checkerboard' dna-dna hybridization method. | 2006 | 16390335 |
| streptococcus intermedius liver abscesses and colon cancer: a case report. | certain species of bacteria are known to be associated with colorectal cancer. we report a case of adenocarcinoma of the colon with bacteraemia and liver abscesses due to streptococcus intermedius. the isolation of this organism should prompt investigation for colorectal neoplasm, which may be present but asymptomatic, without metastases, and therefore at a curative stage. | 2005 | 16459520 |
| effect of a stannous fluoride dentifrice on the sulcular microbiota: a prospective cohort study in subjects with various levels of periodontal inflammation. | to assess the effects of an experimental 0.454% stannous fluoride (snf2) dentifrice on the oral sulcular microbiota in patients with various stages of oral diseases using checkerboard dna-dna hybridization. | 2005 | 16475455 |
| is pre-term labour associated with periodontitis in a danish maternity ward? | to reveal differences in periodontal status and presence of subgingival bacteria in a scandinavian population of women with pre-term birth compared with women who delivered at term. | 2006 | 16489943 |
| deep neck infection complicating lymphadenitis caused by streptococcus intermedius in an immunocompetent child. | streptococcus intermedius belongs to the streptococcus anginosus group. it is part of the normal flora of the human mouth, but it can be etiologically associated with deep-site infections. | 2006 | 16553945 |
| identification of oral bacteria associated with crevicular epithelial cells from chronic periodontitis lesions. | bacterial invasion of host epithelial cells plays an important role in the pathogenesis of periodontal diseases; however, the interactions between subgingival species and the gingival crevice cells are not fully understood. this study determined the prevalence of a group of oral bacterial species on or in epithelial cells derived from periodontal pockets and the gingival crevice of subjects with periodontitis. samples of epithelial cells were obtained from 120 sites with periodontal pockets > or ... | 2006 | 16585650 |
| effect of oral bacteria on growth and survival of candida albicans biofilms. | the purpose of this study was to evaluate the effect of eight aerobic and anaerobic oral commensal bacterial species on in vitro candida albicans biofilm development. a single isolate of c. albicans 2560 g, and eight different species of oral bacteria comprising, actinomyces israelii, lactobacillus acidophilus, prevotella nigrescens, porphyromonas gingivalis, pseudomonas aeruginosa, escherichia coli, streptococcus mutans, and streptococcus intermedius were studied using an in vitro biofilm assay ... | 2006 | 16620775 |
| streptococcus intermedius: an unusual cause of a primary empyema. | despite the evolution of modern antibiotics, pleural space infection remains a common illness with significant morbidity and mortality. every year up to 60 percent of the 1.2 million patients in the united states who present with community-acquired pneumonia develop parapneumonic pleural effusions. few of these parapneumonic effusions progress to an empyema. interestingly, in about 10 percent of the cases of empyema, no underlying pulmonary infection can be identified. these pleural space infect ... | 2006 | 16681236 |
| thigh abscess caused by eikenella corrodens and streptococcus intermedius: a case report. | a 35-year-old chinese female has a large thigh abscess without a clear source. no underlying diseases were revealed in the patient. the combination of clindamycin and cefazolin or vancomycin was administered but without a clinical response. eikenella corrodens and streptococcus intermedius were isolated from puncture drainage. then, ceftriaxone was administered and a surgery of incision and further draining was carried. eventually, the patient recovered. to our knowledge, this is the first case ... | 2007 | 16682079 |
| case of the month. brain abscess. | | 2006 | 16722049 |
| a case of streptococcus intermedius empyema. | to report a case of empyema caused by streptococcus intermedius as a complication of community-acquired pneumonia (cap). | 2006 | 16735670 |
| [psoas abscesses. an up-dated perspective]. | to analyze the characteristics of abscesses of the psoas muscle and assess the differences between pyogenic and tuberculous abscesses. | 2006 | 16762257 |
| bacterial profile and burden of periodontal infection in subjects with a diagnosis of acute coronary syndrome. | periodontitis has been identified as a potential risk factor in cardiovascular diseases. it is possible that the stimulation of host responses to oral infections may result in vascular damage and the inducement of blood clotting. the aim of this study was to assess the role of periodontal infection and bacterial burden as an explanatory variable to the activation of the inflammatory process leading to acute coronary syndrome (acs). | 2006 | 16805672 |
| [subdural empyema in children: therapeutic strategy. five cases]. | we report a series of five subdural empyema (sde) in children and young adults treated in the same neurosurgical department. these five cases were reviewed retrospectively. there were four boys and one girl, aged from three months to 18 years at time of diagnosis (median age: 7 years). sde following intracranial surgery were excluded from the study. all patients were treated surgically (burr hole evacuation or craniotomy, repeated in some cases), followed by intravenous antibiotic therapy (mean ... | 2006 | 16840970 |
| acetaldehyde production from ethanol by oral streptococci. | alcohol is a well documented risk factor for upper digestive tract cancers. it has been shown that acetaldehyde, the first metabolite of ethanol is carcinogenic. the role of microbes in the production of acetaldehyde to the oral cavity has previously been described in several studies. in the present study, the aim was to investigate the capability of viridans group streptococci of normal oral flora to produce acetaldehyde in vitro during ethanol incubation. furthermore, the aim was to measure th ... | 2007 | 16859955 |
| alternative roles for cd59. | cd59 was first identified as a regulator of the terminal pathway of complement, which acts by binding to the c8/c9 components of the assembling membrane attack complex (mac), to inhibit formation of the lytic pore. structurally, cd59 is a small, highly glycosylated, gpi-linked protein, with a wide expression profile. functionally, the role of cd59 in complement regulation is well-defined but studies have also shown clear evidence for signalling properties, which are linked to its glycophosphatid ... | 2007 | 16884774 |
| ribotyping of bacteria from root canal and blood of patients receiving endodontic therapy. | dna restriction patterns and corresponding ribotypes of 26 bacterial isolates (propionibacterium acnes, peptostreptococcus prevotii, fusobacterium nucleatum, prevotella intermedia, prevotella nigrescens, actinomyces israelii, streptococcus intermedius, and streptococcus sanguis) recovered from patients with infected root canals and their peripheral blood, collected during and after endodontic therapy, were examined. eleven additional reference strains including type strains were also examined. p ... | 1997 | 16887597 |
| the micro-flora of the small bowel in health and disease. | the micro-flora of the proximal jejunum in healthy volunteers was compared with the micro-flora in patients with gastrointestinal symptoms suggestive of spontaneous bacterial overgrowth in the small intestine. biopsies were taken distally to the ligament of treitz with a watson capsule. the samples were diluted and inoculated on selective and non-selective agar plates that were incubated aerobically and anaerobically. no major differences were found in the small jejunum micro-flora in healthy pe ... | 2003 | 16887682 |
| association of eubacterium nodatum and treponema denticola with human periodontitis lesions. | the purpose of the present investigation was to compare the levels, proportions and percentage of sites colonized by 40 bacterial species in subgingival plaque samples from periodontally healthy subjects and patients with chronic periodontitis to seek possible pathogens other than the consensus pathogens porphyromonas gingivalis and tannerella forsythia. | 2006 | 16922925 |
| [a case of pulmonary abscess in which haemophilus parainfluenzae and streptococcus intermedius were isolated by percutaneous needle aspiration]. | some microbes, including the bacteroides species, staphylococcus aureus and streptococcus milleri groups, can cause pulmonary abscess. haemophilus parainfluenzae is usually categorized as one of the normal flora which colonizes in the ears and the nasopharynx, and it has been long considered that h. parainfluenzae has little pathogenicity in the lower respiratory tract and lung parenchymal. in this report, we present a case of pulmonary abscess caused by both h. parainfluenzae and streptococcus ... | 2006 | 16972613 |
| paraneoplastic syndrome, infection or arthritis: difficulties in diagnosis. | many different diseases have overlapping clinical symptoms. a major challenge in daily clinical practice is to differentiate between diseases associated with systemic inflammation, such as neoplasia, infection and autoimmune disease. we report on a 46-year-old caucasian male with a 3-month history of rheumatoid arthritis presenting with dramatic weight loss and dysphagia. computer tomography revealed multiple lesions in the liver and the spleen, strongly suggesting malignant disease of unknown o ... | 2006 | 16981976 |
| tigecycline (gar-936) activity against streptococcus gallolyticus (bovis) and viridans group streptococci. | viridans group streptococci including streptococcus gallolyticus (formerly s. bovis) represent serious invasive pathogens often associated with endocarditis or sepsis among immunocompromised or cancer patients. tigecycline (gar-936), the first clinically studied glycylcycline, has a potent gram-positive activity with a potential treatment option for these streptococcal infections. the studied collection (848 strains) included 100 isolates each of streptococcus anginosus, streptococcus constellat ... | 2007 | 16989974 |
| case report: brain and liver abscesses caused by oral infection with streptococcus intermedius. | organ abscesses are a rare and life-threatening complication mostly of hematogenously disseminated infections. we report a case of brain and liver abscesses. identification of the lesions was made by contrast-enhanced computed tomography (ct) and magnetic resonance imaging (mri), respectively. an oral examination comprised an oral focus of infection. streptococcus intermedius was isolated from oral smear, liver and ventricular drainage, and blood sample. after the commencement of antibiotic ther ... | 2006 | 16997089 |
| percutaneous pfo closure for the prevention of recurrent brain abscess. | a patent foramen ovale (pfo) can act as a conduit between the venous and arterial circulations, allowing right-to-left shunting and bypass of the pulmonary circulation. brain abscess may develop as a result of paradoxical embolism of organisms through a pfo. in this small series, we report on the closure of pfo for the prevention of recurrent brain abscess. only prospective, randomized trials comparing pfo closure to conservative therapy could provide a definitive answer as to the optimal strate ... | 2006 | 17086523 |
| molecular dynamics of human-specific cytolysin: analysis of membrane binding motif for therapeutic application. | intermedilysin (ily) is a human-specific cytolysin secreted from streptococcus intermedius. in this study, the dynamic structure of ily, streptolysino (slo) and their 12mer substituted mutants for 500 ps was analyzed. several parameters, such as dipole moment and electrostatic potential, were determined to elucidate the molecular mechanism of membrane binding. | 2006 | 17195457 |
| specific protein-membrane contacts are required for prepore and pore assembly by a cholesterol-dependent cytolysin. | three short hydrophobic loops and a conserved undecapeptide at the tip of domain 4 (d4) of the cholesterol-dependent cytolysins (cdcs) mediate the binding of the cdc monomers to cholesterol-rich cell membranes. but intermedilysin (ily), from streptococcus intermedius, does not bind to cholesterol-rich membranes unless they contain the human protein cd59. this observation suggested that the d4 loops, which include loops l1-l3 and the undecapeptide, of ily were no longer required for its cell bind ... | 2007 | 17412689 |
| the microbiological profiles of saliva, supragingival and subgingival plaque and dental caries in adults with and without type 2 diabetes mellitus. | the relationships between suspected bacteria in saliva, yeasts in oral rinse, and supragingival and subgingival plaque versus root surface and coronal caries in adults with type 2 diabetes mellitus and a non-diabetic group were explored. | 2007 | 17488443 |
| conformational changes that effect oligomerization and initiate pore formation are triggered throughout perfringolysin o upon binding to cholesterol. | pore formation by the cholesterol-dependent cytolysins (cdcs) requires the presence of cholesterol in the target membrane. cholesterol was long thought to be the cellular receptor for these toxins, but not all cdcs require cholesterol for binding. intermedilysin, secreted by streptococcus intermedius, only binds to membranes containing the human protein cd59 but forms pores only if the membrane contains sufficient cholesterol. in contrast, perfringolysin o (pfo), secreted by clostridium perfring ... | 2007 | 17553799 |
| primary ventriculitis caused by streptococcus intermedius. | streptococcus intermedius is increasingly being recognised as an aetiological agent in central nervous system infections. primary ventriculitis caused by this organism has not been reported so far. we present a case of primary ventriculitis, which resulted in adhesions and multiloculated hydrocephalus, necessitating numerous surgical procedures to control it. no predisposing factor(s) could be identified. although the organism could not be cultured from csf, as he was already on antibiotic treat ... | 2007 | 17612921 |
| lemierre syndrome associated with dental infections. report of one case and review of the literature. | the first publication on lemierre syndrome appears in 1936 by lemierre. it is defined as an "oropharynx bacterial infection characterized by the thrombophlebitis in the internal jugular vein, derived in a systemic septic embolism". in 81% of the cases, the fusobacterium necrophorum is the most frequent etiologic agent. fever is the most common symptom, but it can depending on the primary infection, tonsillitis, mastoiditis or odontogenic infection. according to the literature the mortality is ve ... | 2007 | 17767106 |
| synthetic bromated furanone inhibits autoinducer-2-mediated communication and biofilm formation in oral streptococci. | autoinducer-2 (ai-2) is a widespread communication-signal molecule that allows bacteria to sense and react to environmental factors. in some streptococci ai-2 is reported to be involved in virulence expression and biofilm formation. it has earlier been shown that the alga delisea pulchra produces bromated furanones, which prevent bacterial colonization of the algae. | 2007 | 17803632 |
| histone-like dna binding protein of streptococcus intermedius induces the expression of pro-inflammatory cytokines in human monocytes via activation of erk1/2 and jnk pathways. | streptococcus intermedius is a commensal associated with serious, deep-seated purulent infections in major organs, such as the brain and liver. histone-like dna binding protein (hlp) is an accessory architectural protein in a variety of bacterial cellular processes. in this study, we investigated the mechanisms of pro-inflammatory cytokine inductions in thp-1 cells by stimulation with recombinant hlp of s. intermedius (rsi-hlp). rsi-hlp stimulation-induced production of pro-inflammatory cytokine ... | 2008 | 17883418 |
| cranio-spinal subdural empyema due to s. intermedius: a case report. | subdural empyema represents a loculated infection between the dura and the arachnoid. it has been described either intracranially or in the spinal canal, the latter localization being quite rare. while treatment guidelines for a single (either brain or spinal) localization of a subdural empyema are more or less established, its management when a massive involvement of cns is evident represents a challenge. | 2007 | 17894630 |
| [primary pyomyositis caused by streptococcus intermedius]. | pyomyositis is a sub-acute bacterial infection that affects the striated muscle and is usually accompanied by the formation of an abscess in this muscle. it was initially described as an endemic disease in the tropics and only in recent years has an increase been observed in the number of cases in countries with a temperate climate in relation to an increase of immuno-depressed patients. the causal germ is staphylococcus aureus in more than 75% of cases. the most useful imaging test is magnetic ... | 2007 | 17898821 |
| analysis of the antimicrobial activity of local anaesthetics used for dental analgesia. | seven local anaesthetics and their active anaesthetic components [ultracaine d-s (articaine hydrochloride), carbostesin (bupivacaine hydrochloride), scandicaine (mepivacaine hydrochloride), xylonest (prilocaine hydrochloride), xylocaine (lidocaine hydrochloride), hostacaine (butanilicaine phosphate) and novocaine (procaine hydrochloride)] were tested for their antimicrobial activity against 311 bacterial strains from 52 different species and 14 candida albicans strains. the tested pathogens were ... | 2008 | 18065672 |
| structural elements of the cholesterol-dependent cytolysins that are responsible for their cholesterol-sensitive membrane interactions. | the pore-forming mechanism of the cholesterol-dependent cytolysins (cdcs) exhibits an absolute requirement for membrane cholesterol. the structural elements of the cdcs that mediate this interaction are not well understood. three short hydrophobic loops (l1-l3) and a highly conserved undecapeptide sequence at the tip of domain 4 of the cdc structure are known to anchor the cdc to the membrane. it has been thought that the undecapeptide directly mediates the interaction of the cdcs with a cholest ... | 2007 | 18077338 |
| splenic abscess in an infant caused by streptococcus intermedius. | we report a 20-month-old girl with splenic abscess. the patient was admitted to our hospital because of persistent high fever and abdominal pain. laboratory data showed leucocytosis and elevated c-reactive protein levels. abdominal computed tomography showed multiple low-density lesions in the spleen. these findings were consistent with a diagnosis of splenic abscess. she was successfully treated with ultrasonographically guided percutaneous drainage for 11 days and intravenous antibiotic for 17 ... | 2007 | 18095094 |
| rapid conditional targeted ablation of cells expressing human cd59 in transgenic mice by intermedilysin. | conditional targeted cell ablation is a powerful approach for investigating the pathogenesis of human diseases and in vivo cellular functions. intermedilysin (ily) is a cytolytic pore-forming toxin secreted by streptococcus intermedius that lyses human cells exclusively, owing to its receptor specificity for human cd59. we generated two transgenic mouse strains that express human cd59 either on erythrocytes (strain thcd59(rbc)) or on endothelia (strain thcd59(end)). intravenous injection of ily ... | 2008 | 18157141 |
| luxs and expression of virulence factors in streptococcus intermedius. | autoinducer-2 (ai-2) is used by several bacteria in quorum-sensing signaling and is a product of luxs. the aim was to investigate the effect of luxs mutation on expression of streptococcus intermedius virulence factors. | 2008 | 18173802 |
| role of hyaluronidase in streptococcus intermedius biofilm. | streptococcus intermedius is found in biofilms on teeth and as a commensal member of the gastrointestinal and urinary floras, but may also be associated with deep-seated purulent infections and infective endocarditis. s. intermedius produces hyaluronidase, an enzyme that breaks down hyaluronan (ha), a major component of the extracellular matrix of connective tissue. we investigated the involvement of hyaluronidase in s. intermedius biofilm formation and dispersal as well as adhesion to human cel ... | 2008 | 18310039 |
| a possible role of histone-like dna-binding protein of streptococcus intermedius in the pathogenesis of bile duct damage in primary biliary cirrhosis. | bacterial infection has become a focus of attention in the pathogenesis of primary biliary cirrhosis (pbc). it was reported that anti-histone autoantibody was detected in pbc, suggesting that bacterial histone-like dna-binding protein (hlp) may be involved in the pathogenesis of pbc. to identify bacterial species in pbc to confirm this possibility, serum reactivity to bacterial cells was studied by elisa. the igm class streptococcus intermedius titers were significantly higher in pbc than chroni ... | 2008 | 18337173 |
| functional and phylogenetic characterization of vaginolysin, the human-specific cytolysin from gardnerella vaginalis. | pore-forming toxins are essential to the virulence of a wide variety of pathogenic bacteria. gardnerella vaginalis is a bacterial species associated with bacterial vaginosis (bv) and its significant adverse sequelae, including preterm birth and acquisition of human immunodeficiency virus. g. vaginalis makes a protein toxin that generates host immune responses and has been hypothesized to be involved in the pathogenesis of bv. we demonstrate that g. vaginalis produces a toxin (vaginolysin [vly]) ... | 2008 | 18390664 |