| in vitro activity of biapenem plus rpx7009, a carbapenem combined with a serine β-lactamase inhibitor, against anaerobic bacteria. | biapenem is a carbapenem being developed in combination with rpx7009, a new inhibitor of serine β-lactamases. biapenem was tested alone and in combination with fixed concentrations of rpx7009 by agar dilution against 377 recent isolates of anaerobes. a separate panel of 27 isolates of bacteroides spp. with decreased susceptibility or resistance to imipenem was also tested. comparator drugs included meropenem, piperacillin-tazobactam, ampicillin-sulbactam, cefoxitin, ceftazidime, metronidazole, c ... | 2013 | 23529731 |
| comparison of human gut microbiota in control subjects and patients with colorectal carcinoma in adenoma: terminal restriction fragment length polymorphism and next-generation sequencing analyses. | colorectal cancer (crc) is the third leading cause of cancer-related deaths in japan. the etiology of crc has been linked to numerous factors including genetic mutation, diet, life style, inflammation, and recently, the gut microbiota. however, crc-associated gut microbiota is still largely unexamined. this study used terminal restriction fragment length polymorphism (t-rflp) and next-generation sequencing (ngs) to analyze and compare gut microbiota of japanese control subjects and japanese pati ... | 2016 | 26549775 |
| serum electrolytes and parathyroid hormone in patients in a coronary care unit. | a prospective study was carried out in 499 patients admitted to a coronary care unit (ccu) in order to evaluate the incidence of clinically significant electrolyte disturbances. low serum potassium values (less than 3.6 mmol l) occurred in 7% of the ccu patients and low serum magnesium values (less than 0.70 mmol l-1) in 6%. few patients had low values of both these ions (1.9%). in 49 patients the contents of these electrolytes in muscle biopsies were similar to the values of control subjects an ... | 2006 | 2563748 |
| [studies on visual acuity and color perception in the water]. | | 2015 | 4476181 |
| personality characteristics of sex offenders: a review. | research utilizing psychometric instruments to assess personality characteristics of sex offenders is reviewed. a methodological shortcoming of this research is the frequent use of the mmpi. it is argued that this test was originally developed as a measure of types of psychopathology and has not been validated as a personality test. studies using tests other than the mmpi have seldom controlled for institutionalization and impression management. further, little attention has been paid to crimina ... | 2012 | 3579558 |
| [infection prevention manual. prevention of hospital infection and the legally required precautions]. | | 2011 | 3199561 |
| development of ulcerative colitis and its associated colorectal neoplasia as a model of the organ-specific chronic inflammation-carcinoma sequence. | the organ-specific chronic inflammation-carcinoma sequence was summarized and proposed. as a typical model, the ulcerative colitis (uc)--uc-associated carcinoma sequence was selected, and the mechanism of development of uc and uc-associated carcinoma was reviewed, referring mainly to our data. intestinal commensal bacteria, including fusobacterium varium, obtained from the colonic mucosa of uc patients, can enter colonic epithelia and induce secretion of inflammatory cytokines, resulting in earl ... | 2012 | 22612505 |
| nested culture method improves detection of fusobacterium from stool in patients with ulcerative colitis. | fusobacterium varium is an elusive pathogenic factor in ulcerative colitis (uc); conventional methods of fecal culture rarely recover f. varium. we have developed a nested culture method to recover fusobacterium and we used it to investigate whether f. varium could be isolated from uc patients. we enrolled 50 consecutive patients in this study; 26 received combination antibiotic therapy that included amoxicillin, tetracycline, and metronidazole (atm) for 2 weeks and were thus assigned to the atm ... | 2013 | 23514906 |
| increased bacterial putrescine has no impact on gut morphology and physiology in gnotobiotic adolescent mice. | gut bacteria influence host anatomy and physiology. it has been proposed that bacterial metabolites including polyamines are responsible for intestinal maturation and mucosal growth. we have hypothesised that bacterially produced polyamines act as trophic factors and thereby influence large intestinal crypt depth and thickness of the different gut layers. for that purpose, germ-free mice were associated with two different microbial consortia. one group was colonised with a simplified human micro ... | 2013 | 23666100 |
| commentary: adjunct antibiotic combination therapy for ulcerative colitis--is it time to investigate fusobacterium varium? | | 2014 | 24803247 |
| commentary: adjunct antibiotic combination therapy for ulcerative colitis--is it time to investigate fusobacterium varium? authors' reply. | | 2014 | 24803248 |
| fusobacterium varium in ulcerative colitis: is it population-based? | | 2015 | 25311584 |
| hypnocyclicus thermotrophus gen. nov., sp. nov. isolated from a microbial mat in a hydrothermal vent field. | the bacterial strain, ir-2t, was isolated from a microbial mat sampled near a hydrothermal vent in the greenland sea. phylogenetic analysis, based on the 16s rrna gene, showed that the closest relatives of ir-2t were ilyobacter tartaricus, ilyobacter insuetus, propionigenium modestum and fusobacterium varium (91 % 16s rrna gene sequence similarity). the cells of the novel strain were gram-stain-negative and pleomorphic; changing from long motile rods to non-motile ring structures during the grow ... | 2015 | 26373292 |