| pcr-based identification of vibrio cholerae and the closely related species vibrio mimicus using the large chromosomal ori sequence of vibrio cholerae. | the bacterial chromosomal replication origin (ori) sequences are a highly conserved essential genetic element. in this study, the large chromosomal replication origin sequence of vibrio cholerae (oricivc) has been targeted for identification of the organism, including the biotypes of serogroup o1. the oricivc sequence-based pcr assay specifically amplified an 890 bp fragment from all the v. cholerae strains examined. a point mutation in the oricivc sequence of the classical biotype of o1 serogro ... | 2006 | 16553836 |
| presence of luxs/ai-2 based quorum-sensing system in vibrio mimicus : luxo controls protease activity. | presence of the quorum-sensing regulation system in vibrio mimicus was investigated. the culture supernatants of v. mimicus strains were found to possess ai-2 autoinducer like activity, and the strains were found to harbor the genes which are homologous to luxs, luxo, and luxr of v. harveyi. these genes of v. harveyi have been shown to be important components of v. harveyi-like quorum-sensing system. the luxo gene homologue known to encode luxo, the central component of the regulation system, wa ... | 2006 | 16714849 |
| development of monoclonal antibodies for simple identification of vibrio alginolyticus. | the present study was aimed to produce monoclonal antibodies (mabs) for simple and specific identification of vibrio alginolyticus infection in shrimp. | 2006 | 16965376 |
| isolation of vibrio mimicus from a case of acute diarrhoea--a case report. | over a four months period (june to september, 2003) 111 stool samples from cases of acute diarrhoea were screened for vibronaceae in department of microbiology, smt. n. h. l. municipal medical college, ahmedabad. all the isolates were identified by standard laboratory technique. a total of 36 species belonging to vibrionaceae were isolated. phage typing of all these vibronaceae were done at national institute of cholera and enteric disease, kolkata. out of 36 isolates, 35 were vibrio cholereae a ... | 2006 | 17001922 |
| haemolysin produced by vibrio mimicus activates two cl- secretory pathways in cultured intestinal-like caco-2 cells. | haemolysin (vmh) is a virulent factor produced by vibrio mimicus, a human pathogen that causes diarrhoea. as intestinal epithelial cells are the primary targets of haemolysin, we investigated its effects on ion transport in human colonic epithelial caco-2 cells. vmh increased the cellular short circuit current (isc), used to estimated ion fluxes, and 125i efflux of the cells. the vmh-induced increases in isc and 125i efflux were suppressed by depleting ca2+ from the medium or by pretreating the ... | 2007 | 17026482 |
| microwave irradiation for shortening the processing time of samples of flagellated bacteria for scanning electron microscopy. | microwave irradiation (mwi) has been applied to the development of rapid methods to process biological samples for scanning electron microscopy (sem). in this paper we propose two simple and quick techniques for processing bacteria (proteus mirabilis and vibrio mimicus) for sem using mwi. in the simplest methodology, the bacteria were placed on a cover-glass, air-dried, and submitted to conductivity stain. the reagent used for the conductivity stain was the mordant of a light microscopy staining ... | 2004 | 17061527 |
| identification of vibrio isolates by a multiplex pcr assay and rpob sequence determination. | vibrio, a diverse genus of aquatic bacteria, currently includes 72 species, 12 of which occur in human clinical samples. of these 12, three species--vibrio cholerae, vibrio parahaemolyticus, and vibrio vulnificus-account for the majority of vibrio infections in humans. rapid and accurate identification of vibrio species has been problematic because phenotypic characteristics are variable within species and biochemical identification requires 2 or more days to complete. to facilitate the identifi ... | 2007 | 17093013 |
| proteolytic activation of vibrio mimicus (vm) major outer membrane protein haemagglutinin (ha) with vm-ha/protease: implication for understanding bacterial adherence. | vibrio mimicus (vm) haemagglutinins (has), such as an extracellular ha/protease (vm-ha/protease) and a major outer membrane protein-ha (vm-ompha), have been recognized as the putative adherence factors for the bacterium. however, the mechanism by which has coordinate the adherence function of the bacterium remains as yet unknown. we report herein the positive interaction between vm-ha/protease and vm-ompha resulting in significant enhancement of the haemagglutinating ability. in this interaction ... | 2006 | 17116978 |
| catecholamine-induced stimulation of growth in vibrio species. | to evaluate the effect of norepinephrine (ne) and related compounds on the growth of bacteria, we have examined the effect of the neuroendocrine hormone ne and related compounds on the growth of vibrio parahaemolyticus and other human-pathogenic vibrio species (vibrio cholerae, vibrio vulnificus, and vibrio mimicus). | 2007 | 17576228 |
| rapid and specific identification of 5 human pathogenic vibrio species by multiplex polymerase chain reaction targeted to dnaj gene. | a multiplex polymerase chain reaction (pcr) method, specifically designed for application in routine diagnostic laboratories, was developed for identifying 5 human pathogen vibrio species: vibrio cholerae, vibrio parahaemolyticus, vibrio vulnificus, vibrio mimicus, and vibrio alginolyticus. this assay directed toward the dnaj gene was tested on a total of 355 strains representing 13 vibrio species and 17 non-vibrio species. specific pcr fragments were produced in isolates belonging to the 5 targ ... | 2007 | 17614235 |
| identification of vibrio cholerae and vibrio mimicus by multilocus sequence analysis (mlsa). | vibrio cholerae and vibrio mimicus have similar phenotypes and genomes making rapid differentiation of these two species difficult. the first standard multilocus sequence analysis (mlsa) scheme for the identification of these species is described. a collection of 45 representative isolates from different geographical regions and hosts was examined using segments of the housekeeping genes pyrh, reca and rpoa. overall, the closest phylogenetic neighbours of these species were vibrio furnissii and ... | 2008 | 18319466 |
| improvement of innate immune responses and defense activity in mitten crab (eriocheir sinensis) by oral administration of beta-glucan. | the beta-glucan (bg), extracted from saccharomyces cerevisiae cell wall, was orally administrated to the mitten crab (eriocheir sinensis) at 0, 1, 5 and 10 g bg/kg diet for 28 days, followed by a challenge with vibrio mimicus by intramuscular injection. growth, phenoloxidase, superoxide dismutase, acid phosphatase and alkaline phosphatase activity were monitored after 14 and 28 days. the results showed an immunomodulatory effect and protection against v. mimicus by dietary supplementation of bg. ... | 2008 | 18568402 |
| a methoxylated fatty acid isolated from the brown seaweed ishige okamurae inhibits bacterial phospholipase a2. | a methoxylated fatty acid that inhibits phospholipase a(2) (pla(2); ec 3.1.1.4) was purified from the brown seaweed ishige okamurae. approximately 8.1 mg of the inhibitory compound, 7-methoxy-9-methylhexadeca-4,8-dienoic acid, was isolated from 1 kg of i. okamurae powder. recombinant pla(2) derived from the pathogenic bacterium vibrio mimicus was used as the target enzyme. the methoxylated fatty acid compound competitively inhibited pla(2) with a ki value of 3.9 microg/ml. the concentrations req ... | 2008 | 18570268 |
| vibrio porteresiae sp. nov., a diazotrophic bacterium isolated from a mangrove-associated wild rice (porteresia coarctata tateoka). | two facultatively anaerobic, nitrogen-fixing bacteria (strains mssrf30(t) and mssrf31) were isolated from a mangrove-associated wild rice (porteresia coarctata tateoka). these strains were determined to be nitrogen-fixers using the acetylene reduction assay and by pcr detection of a nifh gene amplicon. phylogenetic analyses based on 16s rrna gene sequences indicated that the novel strains were most closely related to vibrio fluvialis lmg 7894(t) (96.8 % gene sequence similarity), vibrio furnissi ... | 2008 | 18599703 |
| an incidence of large foodborne outbreak associated with vibrio mimicus. | | 2009 | 18925423 |
| expression of a fusion protein containing human epidermal growth factor and the collagen-binding domain of vibrio mimicus metalloprotease. | human epidermal growth factor (hegf) is a polypeptide of 53 amino acids, is an important autocrine/paracrine factor in the human body, and is used in the pharmaceutical and cosmetics industries. we constructed a fusion hegf protein with a collagen-binding domain (cbd) composed of 33 amino acids from vibrio mimicus metalloprotease (vmcbd). the cbd segment of the metalloprotease was fused at the c terminus of the hegf protein. the recombinant fusion protein was expressed in escherichia coli and pu ... | 2009 | 18931974 |
| modulation of vibrio mimicus hemolysin through limited proteolysis by an endogenous metalloprotease. | vibrio mimicus is a causative agent of human gastroenteritis and food poisoning, and this species produces an enterotoxic hemolysin (v. mimicus hemolysin) as a virulence determinant. vibrio mimicus hemolysin is secreted as an 80 kda precursor, which is later converted to the 66 kda mature toxin through removal of an n-terminal propeptide via cleavage of the arg151-ser152 bond. in this article, we investigate the role of the endogenous metalloprotease (v. mimicus protease) in the maturation of v. ... | 2009 | 19143841 |
| mycotic abdominal aortic aneurysm infected by vibrio mimicus: report of a case. | this report describes a case of a mycotic aneurysm of the infrarenal abdominal aorta infected by vibrio mimicus, which is the only such case ever reported in the literature. the 80-year-old male patient was first treated for gastroenteritis for 7 days. two months later, he was admitted to the hospital and the aneurysm was diagnosed by three-dimensional computed tomography. the aneurysm was excised and the restoration was done using a 16-mm dacron straight graft. the cultivation of the excised an ... | 2009 | 19198993 |
| dietary supplementation of mannan oligosaccharide improves the immune responses and survival of marron, cherax tenuimanus (smith, 1912) when challenged with different stressors. | three trials were conducted to determine the effects of mannan oligosaccharide (bio-mos ) on the immune responses of marron. in the first trial marron were challenged with vibrio mimicus infection, in the second with nh3 exposure and in the third, the marron were exposed to air during a simulated live transportation trial. for v. mimicus infection and live transportation trials, marron (10.44 +/- 0.20 g and 4.44 +/- 0.20 g initial weights, respectively) were fed three different diets containing ... | 2009 | 19539033 |
| rna colony blot hybridization method for enumeration of culturable vibrio cholerae and vibrio mimicus bacteria. | a species-specific rna colony blot hybridization protocol was developed for enumeration of culturable vibrio cholerae and vibrio mimicus bacteria in environmental water samples. bacterial colonies on selective or nonselective plates were lysed by sodium dodecyl sulfate, and the lysates were immobilized on nylon membranes. a fluorescently labeled oligonucleotide probe targeting a phylogenetic signature sequence of 16s rrna of v. cholerae and v. mimicus was hybridized to rrna molecules immobilized ... | 2009 | 19561182 |
| simultaneous differential detection of human pathogenic and nonpathogenic vibrio species using a multiplex pcr based on gyrb and pnta genes. | to develop a multiplex pcr targeting the gyrb and pnta genes for vibrio species differentiation. | 2010 | 19891709 |
| validation of a method for the detection of five species, serogroups, biotypes and virulence factors of vibrio by multiplex pcr in fish and seafood. | in this work a sequential multiplex pcr system was designed and validated for the detection of most frequent foodborne pathogen vibrio species in fish and seafood (vibrio cholerae, vibrio parahaemolyticus, vibrio vulnificus, vibrio alginoliticus and vibrio mimicus). the method proposed functions in a hierarchical way, being composed of an end-point multiplex pcr to detect the presence of dna belonging to the studied species, followed by multiplex pcr and fragment analysis allowing the viability ... | 2010 | 19913702 |
| [development of taqman real-time pcr in detection of aeromonas hydrophila]. | to develop a taqman real-time pcr for the detection of aeromonas hydrophila. | 2009 | 19954074 |
| development of a loop-mediated isothermal amplification assay for sensitive and rapid detection of the tdh and trh genes of vibrio parahaemolyticus and related vibrio species. | thermostable direct hemolysin (tdh) and tdh-related hemolysin (trh) are the major virulence determinants of vibrio parahaemolyticus. trh is further differentiated into trh1 and trh2 on the basis of genetic and phenotypic differences. we developed a novel and highly specific loop-mediated isothermal amplification (lamp) assay for sensitive and rapid detection of the tdh, trh1, and trh2 genes of v. parahaemolyticus. the lamp assay was designed for both combined and individual detection of the tdh, ... | 2010 | 19966027 |
| rapid identification and characterization of vibrio species using whole-cell maldi-tof mass spectrometry. | vibrio identification by means of traditional microbiological methods is time consuming because of the many biochemical tests that have to be performed to distinguish closely related species. this work aimed at evaluating the use of maldi-tof mass spectrometry for the rapid identification of vibrio (v.) spp. as an advantageous application to rapidly discriminate the most important vibrio spp. and distinguish vibrio spp. from closely related bacterial species like photobacterium damselae and grim ... | 2010 | 20059616 |
| occurrence of the vibrio cholerae seventh pandemic vsp-i island and a new variant. | using comparative genomics, we identified a new variant of the vibrio seventh pandemic island-i (vsp-i). results of polymerase chain reaction (pcr) screening for both known vsp-i variants indicate that the novel variant is present only in non-o1/non-o139 strains of v. cholerae and vibrio mimicus. comparative genomics revealed little sequence divergence in the seventh pandemic vsp-i; however, a second insertion site located on the smaller chromosome was identified. although the seventh pandemic v ... | 2010 | 20141327 |
| [simultaneous detection of vibrio cholerae o1 and o139 by real-time quantitative pcr]. | targeting the specific o-antigen gene cluster, a taq-man real-time fluorescence pcr assay was developed to detect 01 and o139 vibrio cholera concurrently and avoid frequently occurred false positives. | 2010 | 20364601 |
| in vitro antibacterial, cytotoxic and antioxidant activities of plant nephelium longan. | the petroleum ether, chloroform and ethyl acetate fractions of ethanol extract of leaf and stem from the plant nephelium longan (fam-sapindaceae) was subjected to antioxidant, antibacterial and cytotoxic activity. all the fractions showed potent antioxidant activity, of which the ethyl acetate and chloroform fraction of leaf demonstrated the strongest antioxidant activity with the ic50 value of 44.28 and 44.31 microg ml(-1), respectively. the petroleum ether extracts (500 microg disc(-1)) of lea ... | 2010 | 20415149 |
| identification of non-coding rnas in environmental vibrios. | the discovery of non-coding rna (ncrna) has been mainly limited to laboratory model systems and human pathogenic bacteria. in this study, we begin to explore the ncrna diversity in four recently sequenced environmental vibrio species (vibrio alginolyticus 40b, vibrio communis 1da3, vibrio mimicus vm573 and vibrio campbellii baa-1116) by performing in silico searches using infernal and rfam for the identification of putative ncrna-encoding genes. this search method resulted in the identification ... | 2010 | 20447992 |
| interaction between vibrio mimicus and acanthamoeba castellanii. | vibrio mimicus is a gram-negative bacterium, which causes gastroenteritis and is closely related to vibrio cholerae. the environmental reservoir of this bacterium is far from defined. acanthamoeba as well as vibrio species are found in diverse aquatic environments. the present study was aimed to investigate the ability of a. castellanii to host v. mimicus, the role of bacterial protease on interaction with a. castellanii and to disclose the ability of cysts to protect intracellular v. mimicus. c ... | 2010 | 20454692 |
| discovery of novel vibrio cholerae vsp-ii genomic islands using comparative genomic analysis. | this report describes vibrio seventh pandemic island ii (vsp-ii) and three novel variants revealed by comparative genomics of 23 vibrio cholerae strains and their presence among a large and diverse collection of v. cholerae isolates. three vsp-ii variants were reported previously and our results demonstrate the presence of three novel vsp-ii in clinical and environmental v. cholerae marked by major deletions and genetic rearrangements. a new vsp-ii cluster was found in the seventh pandemic v. ch ... | 2010 | 20528940 |
| dietary medicinal plant extracts improve growth, immune activity and survival of tilapia oreochromis mossambicus. | the effects of supplementing diets with acetone extract (1% w/w) from four medicinal plants (bermuda grass cynodon dactylon, h(1), beal aegle marmelos, h(2), winter cherry withania somnifera, h(3) and ginger zingiber officinale, h(4)) on growth, the non-specific immune response and ability to resist pathogen infection in tilapia oreochromis mossambicus were assessed. in addition, the antimicrobial properties of the extract were assessed against vibrio alginolyticus, vibrioparahaemolyticus, vibri ... | 2009 | 20735646 |
| notes from the field: vibrio mimicus infection from consuming crayfish --- spokane, washington, june 2010. | on june 24, 2010, the spokane (washington) regional health district (srhd) was notified of two hospitalized patients under intensive care with severe dehydration whose stool specimens yielded vibrio mimicus. cdc was asked to assist with the environmental and epidemiologic investigation. investigators learned that both persons had consumed crayfish on june 20, 2010. the previous day, live crayfish obtained from an online seafood company had been boiled and served warm at a party. the chef reporte ... | 2010 | 21030943 |
| comparative genomics of clinical and environmental vibrio mimicus. | whether vibrio mimicus is a variant of vibrio cholerae or a separate species has been the subject of taxonomic controversy. a genomic analysis was undertaken to resolve the issue. the genomes of v. mimicus mb451, a clinical isolate, and vm223, an environmental isolate, comprise ca. 4,347,971 and 4,313,453 bp and encode 3,802 and 3,290 orfs, respectively. as in other vibrios, chromosome i (c-i) predominantly contains genes necessary for growth and viability, whereas chromosome ii (c-ii) bears gen ... | 2010 | 21078967 |
| presence of genes for type iii secretion system 2 in vibrio mimicus strains. | vibrios, which include more than 100 species, are ubiquitous in marine and estuarine environments, and several of them e.g. vibrio cholerae, v. parahaemolyticus, v. vulnificus and v. mimicus, are pathogens for humans. pathogenic v. parahaemolyticus strains possess two sets of genes for type iii secretion system (t3ss), t3ss1 and t3ss2. the latter are critical for virulence of the organism and be classified into two distinct phylogroups, t3ss2α and t3ss2β, which are reportedly also found in patho ... | 2010 | 21110901 |
| identification and characterization of a vibrio mimicus gene encoding the heme/hemoglobin receptor. | the present authors have previously reported that vibrio mimicus expresses 77-kda and 80-kda outer membrane proteins in response to iron-limited conditions, and that the 77-kda protein serves as the receptor for ferriaerobactin. in this study, it was found that v. mimicus can use heme and hemoglobin as iron sources. furta was then applied to v. mimicus 7pt to obtain candidate gene fragments involved in utilization of heme and hemoglobin. one furta-positive clone was shown to contain a partial ge ... | 2010 | 21118298 |
| development of a single base extension-tag microarray for the detection of pathogenic vibrio species in seafood. | in this study, a single base extension-tag array on glass slides (sbe-tags) microarray was established to detect the seven leading seafood-borne pathogens, including vibrio parahaemolyticus, vibrio cholerae, vibrio vulnificus, vibrio mimicus, vibrio alginolyticus, vibrio anguillarum, and vibrio harveyi. three multiplex pcr assays were developed to specifically target the following species with individual gene markers, which are aads, tdh, and trh for v. parahaemolyticus; col, toxr, and vvh for v ... | 2010 | 21161212 |
| [identification of vibrio mimicus bacteriophages]. | lysogeny was studied in vibrio mimicus; the indicator v. cholerae el tor strain was selected to identify phages. new v. mimicus phages were obtained and identified, which had a morphological similarity and an antigen affinity for morphological group i cholerae phages. phage differentiation revealed that morphological group i v. mimicus phages showed certain differences manifested as their lytic activity against v. cholerae strain 1322-69 of serovar 37 while this property was absent in cholerae p ... | 2011 | 21574461 |
| design and validation of a novel multiplex real-time pcr assay for vibrio pathogen detection. | three species--vibrio cholerae, vibrio parahaemolyticus, and vibrio vulnificus--account for the majority of vibrio infections in humans. rapid and accurate identification of vibrio species has been problematic because phenotypic characteristics are variable within species. additionally, biochemical identification and confirmation require 2 or more days to complete. rapid and sensitive molecular techniques for the detection of vibrio pathogens would be useful for the surveillance and management o ... | 2011 | 21669071 |
| Detection and characterization of pathogenic vibrios in shellfish by a Ligation Detection Reaction-Universal Array approach. | Vibrios are a group of major foodborne pathogens widely distributed in marine environment. Vibrio cholerae, Vibrio parahaemolyticus, and Vibrio vulnificus are the pathogenic species of Vibrio that pose the greatest threat to human health. However, other vibrios, e.g. Vibrio alginolyticus, Vibrio mimicus and Grimontia hollisae, apparently less relevant in the group of foodborne pathogens, have been sporadically found in outbreaks. For seafood safety and economic purposes, a rapid and powerful met ... | 2011 | 22177227 |
| erratum: variation in epitopes of the b subunit of vibrio cholerae non-o1 and vibrio mimicus cholera toxins. | | 1990 | 22049941 |
| structural variation of the superintegron in the toxigenic vibrio cholerae o1 el tor. | to understand the genetic structures and variations of the superintegron (si) in vibrio cholerae isolated in the seventh cholera pandemic. | 2011 | 22365393 |
| mechanism of action of beta-blockers in hypertension. | | 2001 | 14643 |
| statistical analysis of epidemiological data from a chromium chemical manufacturing plant. | a statistical analysis was performed on reported bronchogenic carcinoma incidence in a group of chromium chemical manufacturing workers over the period 1929 to 1977. the purpose was to determine if post-1950 process improvements corresponded to favorable trends in morbidity. because the paucity of data on the population at risk prevented meaningful calculations of smr's, a recently developed method called "probability window analysis" was used to evaluate for statistically valid changes in the " ... | 2003 | 430272 |
| pelvic displacement of a cardiac pacemaker following trauma. a case report. | the rate migration of an implanted cardiac pacemaker from the subrectus area anterior to the peritoneum to the pelvis following a motor vehicle accident is reported. discovery of dislodgement was made by observing a marked increase of pacemaker impulse amplitude in the three standard limb leads as measured on an oscilloscope. | 2003 | 152472 |
| male transsexualism in england: sixteen cases with surgical intervention. | the syndrome of transsexualism is now regarded as a dinstinct entity separate from transvestism and homosexuality (benjamin, 1966; green and money, 1969). it refers to those patients who since childhood have been convinced of their wrong sex assignment and who wish to attain the sexual characteristics of the opposite sex and to live as a member of that sex. the present report is an initial one referring to the first group of transsexual patients studied at a postgraduate teaching hospital by a m ... | 2005 | 1169047 |
| annual summary 1984. reported morbidity and mortality in the united states. | | 2011 | 3092006 |
| software printout. | | 2015 | 4542580 |
| [lysis of the femoral neck and coxa vara (author's transl)]. | | 2015 | 4588540 |
| behaviour of carbonic anhydrase in the uterus of hens during moult. | | 2016 | 4958241 |
| computer-aided molecular modelling: research study or research tool? | developments in computational methods and equipment have produced a new type of research chemist, who prefers to calculate properties as well as measure them, either to gain a better understanding of microscopic molecular behaviour per se, or to guide a broader scientific study using a so-called 'rational' approach. while there is good reason to believe that significant results can be obtained this way, it is clear that only some of the 'tools of the trade' are sufficiently robust to present to ... | 2011 | 3236047 |
| synthesis and antineoplastic effects of furo[3,4-d]pyrimidine derivatives. | furo[3,4-d]pyrimidine was obtained in the reaction of 2-phenyl-4-phenylamino-6-methyl-5-pyrimidinecarboxylic acid with socl2. this compound, heated with aliphatic amines, yielded mono- and diamino-derivatives. some of the obtained compounds exhibited a potent antineoplastic activity. | 2011 | 3237569 |
| oesophageal pain exacerbated by propranolol. | | 2011 | 3113570 |
| the feasibility of an assistant to the physician. | | 2014 | 4152241 |
| [association of an ossicle malformation and a congenital preauricular fistula]. | | 2003 | 142810 |
| [x-ray computed tomography in venous pathology]. | after presenting the tomodensitometric semiology of venous thromboses in various territories, the authors define its indications. it is essentially in deep territories, head, chest and abdomen that the ct-scan is used to study and diagnose unrecognized thromboses as well as determine the venous repercussion of various neighboring ailments. the respective place of the ct-scan, ultrasonography and various phlebographies is analyzed. | 2011 | 3043474 |
| [use of audiovisual equipment in the department of dentistry in japanese universities (2)]. | | 2001 | 95111 |
| overdose with baclofen. | | 2014 | 3945841 |
| interference of bromide in determination of serum chloride. | | 2010 | 3815810 |
| noninvasively diagnosed peripheral arterial disease as a predictor of mortality: results from a prospective study. | intermittent claudication has been reported in previous studies to approximately double the risk of subsequent mortality. however, a history of claudication is often present in the absence of significant peripheral arterial disease (pad) and absent in the presence of pad. for this reason we evaluated the association between large-vessel and small-vessel pad, measured by highly reliable and valid noninvasive tests, and mortality in 567 older subjects from a defined population followed-up for an a ... | 2014 | 4028377 |
| self-evaluation by first-year medical students in a clinical science programme. | | 2016 | 4771337 |
| the mesencephalic exterolateral posterior nucleus of the mormyrid fish bryenomyrus niger: efferent connections studied by the hrp method. | | 1999 | 91414 |
| perinatal mortality. | | 2001 | 93220 |
| [present-day state and perspectives of development of psychotherapy in poland]. | | 2004 | 515249 |
| [massive lower gastrointestinal hemorrhage of diverticular origin. diagnostic and therapeutic problems]. | | 2005 | 1082809 |
| [biochemical aspect in cardiac ischemia--ischemic changes and reperfusion injury]. | | 2010 | 2838873 |
| valproate-associated hepatotoxicity and its biochemical mechanisms. | intake of the anticonvulsant drug valproic acid, or its sodium salt, has been associated with occasional instances of severe and sometimes fatal hepatotoxicity. probably at least 80 cases have occurred worldwide. the syndrome affects perhaps 1 in 10,000 persons taking the drug, and usually develops in the early weeks or months of therapy. most instances have involved children, usually those receiving more than 1 anticonvulsant. multiple cases have occurred in 2 families. the typical presentation ... | 2011 | 3131628 |
| thyroglobulin and 131i uptake of remaining tissue in patients with differentiated carcinoma after thyroidectomy. | in 158 thyroidectomized patients with well-differentiated non-metastatic thyroid cancer the results of serum thyroglobulin (tg) determination and 131i uptake values established immediately before radioiodine treatment (19 days after surgery) were compared. in 113 patients (72%) tg was above 6 ng ml-1 (lower limit of detection) and 131i uptake exceeded 2%. in 11 patients (7%) tg was undetectable and 131i uptake less than 2%. in these cases a radioiodine treatment was not performed; the thyroid ab ... | 2012 | 3399222 |
| galvanic skin responses (gsr) and plethysmographic changes induced by chlorimipramine, imipramine and placebo. | | 2014 | 4209521 |
| torsade de pointes: a maximal vulnerability arrhythmia. | | 2014 | 3966319 |
| [are reforms of dental education necessary?]. | | 2015 | 4510183 |
| hypersomatotropism and acanthosis nigricans in two brothers. | | 2016 | 4843205 |
| [economic aspects of the sao-method in routine orthopedic surgery]. | | 2015 | 4650689 |
| darkroom diseases and how to combat them. | | 2011 | 3112384 |
| anticholinergic drugs in the treatment of airways disease. | | 2010 | 2861843 |
| [disturbances in phosphate metabolism during parenteral alimentation. hypophosphatemic syndrome]. | | 1998 | 24396 |
| [retinal neovascularization: topological, morphological and hemodynamic features (author's transl)]. | | 1999 | 91317 |
| a simple centrifuge column for desalting protein solutions. | | 2005 | 543535 |
| health checks on patients 75 years and over in nottinghamshire after the new gp contract. | to investigate annual health checks for patients of 75 years and over required by the 1990 contract for general practitioners. | 2006 | 1393076 |
| a randomized trial of anticoagulation with warfarin and of alternating chemotherapy in extensive small-cell lung cancer by the cancer and leukemia group b. | the cancer and leukemia group b (calgb) conducted a prospective randomized trial to evaluate the role of warfarin and alternating chemotherapy in extensive small-cell lung cancer (sccl). after stratification for sex and performance status, patients were randomly assigned to receive chemotherapy with methotrexate, doxorubicin (adriamycin; adria laboratories, columbus, oh), cyclophosphamide, and lomustine (ccnu) (macc), or macc plus warfarin (macc + w), or mitomycin, etoposide, cisplatin, and hexa ... | 2008 | 2547030 |
| diagnosis and treatment of chalazia. | a patient with recurrent chalazia is described. this patient also had acne rosacea. the clinical and histologic characteristics of chalazia are described. in addition, therapy for chalazia is presented, with emphasis being given to conservative therapy. | 2013 | 3734179 |
| [acoustic indicator of membrane potential levels]. | | 2013 | 3609385 |
| [effectiveness of the comprehensive treatment by rhonidase electrophoresis and tbilisi sulfide baths of elderly patients suffering from osteoarthrosis deformans]. | | 2003 | 154769 |
| [organization of the regular schedules of forensic-medical experts at a bureau of forensic medical examinations]. | | 2014 | 4071589 |
| seventy-five years of radiological physics. | | 2015 | 4585010 |
| sodium iron nafeedta as an iron fortification compound in central america. absorption studies. | studies were performed in seven children and 98 adults to compare the proportion of iron absorbed when administered as ferric sulfate (fe2(so4)3), nafeedta, hemoglobin (hb), and ferrous ascorbate. studies in children (mostly iron deficient) showed that when the compounds were given with a milk-rice-sugar formula totalling 5 mg fe, iron from hemoglobin was absorbed best, followed by nafeedta and by fe2(so4)3 (mean percent absorption +/-sd = 34.5 +/- 1.5, 8.6 +/- 1.9 and 3.3 +/- 1.5, respectively) ... | 1999 | 96688 |
| mycosis fungoides with verrucous lesions. | | 1999 | 84478 |
| [studies on the blood constituents of the neonates delivered by the induced delivery of the defense medical college method]. | for the assessment of the influence of the defense medical college planned delivery method upon neonates, the measurement of the blood constituents of the umbilical cord was conducted. statistically speaking, no marked differences were seen between the neonates delivered by the defense medical college method and neonates delivered naturally. the blood constituents investigated were: blood cells, activity of various enzymes, other blood constituents and electrolytes. | 2012 | 3457089 |
| agoraphobia and parental bereavement. | the prevalence of parental bereavement was determined in 50 married female outpatients with a dsm-iii diagnosis of agoraphobia and in a control group of married female outpatients diagnosed as having non-psychotic psychiatric disorders other than agoraphobia. the two groups were matched for age and overall severity of psychiatric symptoms. compared with the general population, the patient control group reported a statistically significant excess of parental, but not maternal, bereavement. the ag ... | 2012 | 3435374 |
| [postoperative esophageal stenosis (role of the laryngologist)]. | | 2002 | 153373 |
| renal growth after neonatal urinary tract infection. | this study presents the result of 12-21 years' follow-up in a group of children with neonatal urinary tract infection (onset within 1 month after birth) in whom early renal growth retardation was noted without concomitant classical renal scarring. in all cases the neonatal infection was diagnosed and treated within a few days of onset and the patients were closely supervised thereafter. renal length, parenchymal thickness and area were measured at urography. at first follow-up (22 children, mean ... | 2010 | 3153287 |
| physiology of the upper airways in allergic disease. | | 2014 | 3902190 |
| [care of the injured in the hospital. medico-legal documents furnished them. transmitting care information]. | | 1993 | 262925 |
| [intramural pseudo-diverticulosis of the oesophagus]. | | 1998 | 98947 |
| tetralogy of fallot in adults. | | 1999 | 91440 |
| cofactor recycling in liquid membrane-enzyme systems. | | 1995 | 177010 |
| [evaluation of blood-liquor barrier by protein gradients in congenital hydrocephalus in infancy]. | | 1999 | 88669 |
| effect of antihypertensive drugs on insulin, glucose, and lipid metabolism. | the close relationship between diabetes and hypertension has been recognized for decades. new information indicates that resistance to insulin action on glucose uptake in peripheral tissues is a common underlying mechanism in hypertension and diabetes. in prospective trials, the effects of antihypertensive agents on insulin sensitivity and lipoprotein metabolism have been evaluated. both beta-blockers and thiazide diuretics worsen insulin resistance and deteriorate lipoprotein metabolism. angiot ... | 2006 | 1828417 |
| effect of antihypertensive drugs on insulin, glucose, and lipid metabolism. | the close relationship between diabetes and hypertension has been recognized for decades. new information indicates that resistance to insulin action on glucose uptake in peripheral tissues is a common underlying mechanism in hypertension and diabetes. in prospective trials, the effects of antihypertensive agents on insulin sensitivity and lipoprotein metabolism have been evaluated. both beta-blockers and thiazide diuretics worsen insulin resistance and deteriorate lipoprotein metabolism. angiot ... | 2006 | 1828417 |
| temporal lobe epilepsy with schizophrenia. | i have reported a case of coexisting schizophrenia and complex partial seizures to augment earlier reports of schizophrenia and psychomotor seizures masquerading as one another. i have attempted to clarify the differential diagnosis and reinforce the need to do thorough studies in such cases. | 2013 | 3616704 |