| histochemical observations on pneumocystis carinii: selective demonstration of honeycomb forms. | histochemical investigations of pulmonary lesions indicated selective coloration of membranes of honeycomb stages of pneumocystis carinii by the periodic acid--sodium bisulfite--resorcin-fuchsin reaction for basement membranes; mucus, fibrin and other deposits in respiratory pathways did not react. these membranes were colored selectively also by the picro-sirius red f3ba method for collagens; fungi in tissues from patients with candidiasis remained unstained. for simultaneous demonstration of h ... | 1979 | 92466 |
| nonspecific light loss and intrinsic dna variation problems associated with feulgen dna cytophotometry. | nonspecific light loss by the cell-wall-plus-cytoplasm (cwc) can cause a 50% increase in feulgen absorption units in peanut root-tip nuclei as determined by scanning at 450 nm, whereas this phenomenon is not evident with chicken erythrocytes. a two wavelength scanning method of subtracting nonspecific 450 nm absorption from 550 nm feulgen absorption values eliminated the nonspecific light loss in cwc, however, the two wavelength scanning method is time consuming and somewhat impractical with a r ... | 1979 | 92496 |
| immunoelectron microscopic localization of herpes simplex virus antigens in infected cells using the unlabeled antibody-enzyme method. | subcellular localization of viral antigens was demonstrated during viral morphogenesis using herpes simplex virus type 1 (hsv-1) infected monolayers of rabbit cornea cells. the localization was done by immunoelectron microscopy employing the peroxidase-antiperoxidase (pap) immunocytochemical technique and the postembedding staining method. the localization of viral antigens was followed at time intervals during infection from 2 to 19 hr. after exposure of sections to either polyspecific antibodi ... | 1979 | 92500 |
| evaluation of the validity of the histochemical lead nitrate technique for alkaline and acid deoxyribonuclease. | the results of several tests and the characteristic morphological distribution of the enzymatic activity appeared to be in favor of the validity and specificity of the histochemical lead nitrate technique for alkaline and acid deoxyribonuclease (dnase) detection. these tests included thermal inhibition, omission of substrate, use of different chemical inhibitors and the reproduction of histochemical staining on coujard's slides. most of these results were in conformity with the biochemical data ... | 1979 | 92502 |
| macrophage oxygen-dependent antimicrobial activity. i. susceptibility of toxoplasma gondii to oxygen intermediates. | a sensitive method for evaluating extracellular parasite viability was used to determine the in vitro susceptibility of virulent toxoplasma gondii to selected oxygen intermediates. by acridine orange fluorescent staining criteria, toxoplasmas were resistant to up to either 10(-3) m reagent h2o2 or h2o2 generated by glucose-glucose oxidase. in keeping with a lack of sensitivity to h2o2, toxoplasmas contained endogenous catalase (5.7 x 10(-4) baudhuin units/10(6) organisms). the addition of a pero ... | 1979 | 92521 |
| ia determinants on human t-cell subsets defined by monoclonal antibody. activation stimuli required for expression. | the nature of ia antigens which appear on human t cells after activation and the stimuli required for their expression was examined utilizing a monoclonal antibody reactive with the ia antigen framework. t cells were purified using monoclonal antibodies directed either at the entire t-cell population (okt3) or the t-cell inducer subset (okt4). by indirect immunofluorescence, it was shown that the human t-cell population contains no detectable ia+ cells in the resting state. in contrast, in exces ... | 1979 | 92523 |
| correlation between the capacity of bacterial lipopolysaccharide to supress experimental allergic encephalomyelitis and its mitogenic activity for lymph node cells in guinea pigs. | protection of guinea pigs from experimental allergic encephalomyelitis (eae) was attempted using bacterial lipopolysaccharide (lps) from 4 sources. the ability of these lps to induce dna synthesis in guinea pig lymph node (ln) cells in vitro was also investigated. it was found that there existed a good correlation between the capacity of lps to suppress eae and their degree of mitogenic activities for ln cells. lps from escherichia coli 0111:b4 (ec-lps), which was most effective in suppressing e ... | 1979 | 92530 |
| biologically active polycycloalkanes. 6. antiviral 1-tricyclo[4.3.1.1 2,5]undecyl derivatives. | functionalization reactions via cationic intermediates of tricyclo[4.3.1.1 2,5]undecane (2) were investigated to prepare derivatives with potential antiviral activities. bromination of 2 took place regiospecifically at c-1, and the resulted bromide 5 was converted into the hydroxide 9, the carboxylic acid 12, and the amine 22, from which were synthesized a variety of secondary derivatives, including homologous esters 10 and 20, amides 14 and 19, carbamates 24, and ureas 17 and 25. the hydroxide ... | 1979 | 92566 |
| the accessibility of antigenic determinants of ribosomal protein s4 in situ. | antibodies to escherichia coli ribosomal protein s4 react with s4 in subribosomal particles, eg, the complex of 16s rna with s4, s7, s8, s15, s16, s17, and s19 and the ri reconstitution intermediate, but they do not react with intact 30s subunits. antibodies were isolated by three different methods from antisera obtained during the immunization of eight rabbits. some of these antibody preparations, which contained contaminant antibodies directed against other ribosomal proteins, reacted with sub ... | 1979 | 92615 |
| ultrastructure and partial characterization of a regular array in the cell wall of lactobacillus brevis. | the cell wall of lactobacillus brevis was revealed by electron microscopy to have an outer layer composed of a regular array. the morphological unit of the regular array appeared to consist of four spherical subunits, each about 2 nm in diameter, which were arranged in a tetragonal pattern about 4.5 by 7.0 nm in dimension. the regular array was composed of the tetragonal units in rows in two directions at an angle of about 75 degrees to each other. the average spacing between the rows was about ... | 1979 | 92747 |
| olivocerebellar projections in the cat studied by means of anterograde axonal transport of labelled amino acids as tracers. | | 1979 | 92769 |
| the zinc iodide-osmium (zio) reaction in the central nervous system: localization and relations to functional activity. | the fine structural characteristics of zio reaction was studied in the cerebral and cerebellar cortex and olfactory bulb of the rat and in synaptosomes prepared from rat cerebellar cortex. it was concluded that: 1. organelles of different nerve cell types exhibit different zio reactions provided that the impregnation was carried out under standardized conditions. 2. 6...10 times more synaptic vesicles were stained by zio in the inhibitory terminals than in the excitatory ones. 3. zio positivity ... | 1979 | 92863 |
| alpha-feto-protein (afp) and human chorionic gonadotropin (hcg) as biochemical markers of intracranial germ-cell tumours. | | 1979 | 92878 |
| prostate-specific acid phosphatase: purification and specific antibody production in rabbits. | demonstration of prostate-specific acid phosphatase by immunologic methods in tissue sections or in plasma necessitates a monospecific antiserum. this is produced by immunizing rabbits with pure prostate-specific acid phosphatase antigen, prepared from seminal fluid. the ejaculate is centrifuged, dialyzed against a citrate buffer, ph 4.8, and centrifuged again. the supernatant is brought onto a sephacryl s-200 superfine column and eluted with the same buffer. prostate-specific acid phosphatase-p ... | 1979 | 92890 |
| [relations between oxoglutarate transport function and variations of space in rat heart mitochondria (proceedings)]. | | 1979 | 92958 |
| antigenic similarity of morphologic type ciii1 bacteriophages. | the aim of the study was to demonstrate antigenic differentiation among bacteriophages belonging to the same morphologic type--ciii1 according to krzywy and slopek or a2 according to ackermann. twenty-six bacteriophages which multiplied on various strains of bacteria of the genera escherichia, shigella and klebsiella, were studied. serologic tests were done by the quantitative complement fixation test. immune sera against 5 phi e. coli. d8 sh. flexneri, g35 sh. sonnei and kl7 klebsiella bacterio ... | 1979 | 92976 |
| [two-layer rocket-electrophoresis on cellulose-acetate membranes]. | two-floor rocket-electrophoresis on gelatinated acetate cellulose membrane "cellogel" has been developed. the method is based on electroimmunodiffusion detection of the antigen on the acetate-cellulose membranes, containing monospecific antiserum of the test-system. the procedure is followed by the detection of precipitation bands ("rockets") by staining, if the reaction is conducted in the visible zone or by the further treatment of the acetate-cellulose strips, containing invisible precipitate ... | 1979 | 93004 |
| [immunosuppression in rabbits using the serum of splenectomized animals (author's transl)]. | | 1979 | 93023 |
| the effect of dose loading and of double labelling with 57co and 125i on the tissue distribution in animals. | dose loading effects upon the performance of 57co-bleomycin as a tumor localizing agent have been investigated in rhabdomyosarcoma bearing wag/ry rats. the addition of non-radioactively labelled co-bleomycin increased the relative uptake of 57co-bleomycin in rapid growing tumors, but the addition of non-chelated bleomycin had no influence at all. in our experimental system, iodinated bleomycin generally labelled by reaction with icl, was found to be an unsatisfactory tumor localizing agent. in o ... | 1979 | 93048 |
| [hygienic standards for a mixture of hexachlorane and phosalone in the atmosphere]. | | 1979 | 93066 |
| histochemical reactions of gastrointestinal mucosubstances with high iron diamine after prior oxidation and methylation of tissue sections. | high iron diamine reactions after the prior methylation and oxidation of tissue sections with performic acid or potassium permanganate (metox-hid or ox-met-hid) in epithelial mucosubstances and in mucosal mast cells were studied in tissue samples from the human gastrointestinal tract and were compared with reactions with high iron diamine without any pretreatment (hid) and high iron diamine with the prior methylation (met-hid). high iron diamine reactions after the prior oxidation (met-ox-hid, o ... | 1979 | 93103 |
| analysis of vibrio parahaemolyticus soluble antigens by employing passive hemagglutination. | the passive hemagglutination assay was explored as a sensitive test of immunological reactivity of endotoxin and other antigens prepared from selected strains of vibrio parahaemolyticus. the tannic acid procedure for passive hemagglutination, commonly used with protein antigens, was the only procedure yielding good results with v. parahaemolyticus protein extracts, endotoxins, and related preparations. these results were probably due to the presence of large amounts of protein in the v. parahaem ... | 1979 | 93111 |
| experimental infection with ancylostoma caninum larvae in mice. vi. serum protein pattern use due to repeated exposures to infection. | three mice groups were infected with various repeated doses and other four groups with single doses of ancylostoma caninum larvae. serum samples collected at various intervals were analysed electrophoretically. the results were compared first with an uninfected control group and then with those of the corresponding non-immunized single-dose-infected groups. remarkably decreased values of albumin, increased beta globulin and increased total globulins with a decreased a/g ratio were observed. ther ... | 1979 | 93128 |
| induction of ecotropic endogenous murine leukemia virus in long-term bone marrow cultures from mouse strains of varying natural leukemia incidence. | | 1979 | 93145 |
| suppression by antithyroid drugs of experimental hepatic necrosis after ethanol treatment. effect on thyroid gland or on peripheral deiodination? | | 1979 | 93320 |
| [immunogenicity of human outer segment in human uveitis (author's transl)]. | | 1979 | 93410 |
| relationship of seminal volume to size and disease of the prostate in the beagle. | the seminal volume of young adult beagles was correlated with the size of and disease in their prostates. the ejaculate volume of naturally collected semen increased in a linear manner with prostatic weight in dogs with normal or glandular hyperplastic prostates. this correlation was not observed in the dogs with cystic hyperplasia, in which there was a reduction in volume of 50% in the semen produced for each gram of prostate. there were no significant differences in other seminal characteristi ... | 1979 | 93426 |
| [cis expression, at complementation, of mitochondrial mosaic gene exons regulating cytochrome b in saccharomyces cerevisiae (proceedings)]. | | 1979 | 93454 |
| a novel class of schizosaccharomyces pombe mutants, phenotypically unable to grow on glycerol, a respiratory substrate, but still able to oxidize glycerol aerobically [proceedings]. | | 1979 | 93469 |
| alteration in the immunochemical dominance of determinants following the chemical modification of ox insulins: implications for the structure of the ox insulin monomer in solution. | insulins of differing species, together with chemically modified insulins, were used in cross-reactivity experiments employing selected antisera raised to ox insulin in the harley guinea-pig. the immunogen had been administered as a water-in-oil emulsion, using h. pertussis vaccine as adjuvant. antibody was generated by determinants in the c-terminus of the b chain plus the adjacent n-terminus of the a chain, in the central core of the a chain (a8-a14 region) and in its anti-parallel n-terminus ... | 1979 | 93526 |
| identification and characterization of trypsin, chymotrypsin and elastase inhibitors in porcine serum. | characterization of the trypsin-, chymotrypsin- and elastase-inhibiting properties of porcine serum was carried out by gel filtration on ultrogel, aca 44, and agarose gel electrophoresis with subsequent processing for protease-inhibiting activity. moreover, by allowing the fractions obtained from gel filtration to react with antibodies to porcine serum protease inhibitors, the specific inhibiting properties of these inhibitor molecules were identified. at least six protease inhibitors were ident ... | 1979 | 93564 |
| surface-associated host proteins on virulent treponema pallidum. | a surface coat of host serum proteins was detected on virulent treponema pallidum by sodium dodecyl sulfate-gel electrophoresis. the loosely associated serum proteins could be removed by repeated washings in a protein-free medium. washed t. pallidum retained the ability to readsorb numerous host proteins from rabbit serum as well as iodinated rabbit or human albumin. in addition, various avidly associated host serum proteins including albumin, alpha(2)-macroglobulin, transferrin, ceruloplasmin, ... | 1979 | 93574 |
| antigenic heterogeneity of the non-serogroup antigen structure of neisseria gonorrhoeae lipopolysaccharides. | studies of the antigenic structure of the polysaccharide component of gonococcal lipopolysaccaride (lps) indicated that the non-serogroup antigen structure is antigenically heterogeneous. immunodiffusion studies of gc4 strain 8551 indicated that in addition to the gc serogroup determinent, this polysaccharide contains two other sets of determinants, one which is shared with the other five gc serogroups and a second which is shared by the gc1 and gc3 serogroups. enzyme-linked immunosorbent assay ... | 1979 | 93575 |
| alpha-fetoprotein inhibits antibody binding to acetylcholine receptor. significance for myasthenia gravis and other autoimmune diseases. | | 1979 | 93589 |
| the binding of streptomycin to ribonucleotides. | incubation of streptomycin (sm) with [32p]5'-ribonucleotides at ph 7.0 produces fractions that migrate towards the cathode in high voltage electrophoresis (hve) separations at ph 3.5. sm appears to interact with pg, pa and pc but not with pu. the appearance of these [32p]-labeled fractions is dependent on incubation time and sm concentration. incubation of nucleotides with dihydrostreptomycin (dsm) or sm reduced with sodium cyanoborohydride (nabh3cn) at ph 5.0, does not produce detectable change ... | 1979 | 93596 |
| genetic variation in the m antigen of group a streptococci: reassortment of type-specific markers and possible antigenic drift. | the phylogenetic relationships of 73 strains of group a streptococcus isolated over a six-year period from a population with a high prevalence of streptococcal infections were analyzed with use of four serotype-specific markers: the serum opacity factor (of), the t antigen, the determinant of the m antigen that precipitates with antibody, and the m antiphagocytic determinant. of inhibition tests divided the strains into five subtypes: a, b, c, d, and e. strains within subtypes a, b, and c shared ... | 1979 | 93611 |
| immunoprecipitation of triton x-100-solubilized mycoplasma mycoides proteins. | mycoplasma mycoides subsp. mycoides (pg1 and strain y) proteins were solubilized in triton x-100, and the antigenic proteins were precipitated from this complex mixture by addition of antiserum and then separated by two-dimensional gel electrophoresis. of the 300 proteins solubilized, about 10 were precipitated. proteins of pg1, a slow-growing, small colony (sc) strain, were precipitated by antiserum to pg1 and by antiserum to strain y, a fast-growing, large colony (lc) strain. similarly, strain ... | 1979 | 93614 |
| [changes in the physiologic properties of a chemostat culture of propionibacterium shermanii during growth limitation by a deficiency of sodium lactate]. | a chemostat curve has been constructed for changes in the propionibacterium shermanii population density with an increase in the flow rate of the medium from 0.04 to 0.55 h-1 upon limitation of the growth with sodium lactate deficiency. the curve differs from the classic chemostat curve described with the monod equation, thus indicating changes in metabolism at different growth rates. fermentation of lactate to acetic and propionic acids by the culture is most complete at low flow rates of the m ... | 1979 | 93687 |
| substance p as neurogenic mediator of antidromic vasodilation and neurogenic plasma extravasation. | | 1979 | 93706 |
| location of bladder preganglionic neurons within the sacral parasympathetic nucleus of the cat. | sacral parasympathetic preganglionic neurons innervating the urinary bladder were labelled by applying horseradish peroxidase (hrp) to branches of the pelvic nerve at the neck of the bladder. bladder preganglionic cells were located primarily in the intermediolateral grey matter of sacral cord segments 1, 2 and 3 and extended from the ventral end of the central canal to the inferior margin of the dorsal horn. dendrites extended into the dorsolateral funiculus, toward the lateral edge of the dors ... | 1979 | 93725 |
| problems associated with prolonged wear soft contact lenses. | complications of prolonged wearing of soft contact lenses are corneal infection, peripheral vascularization, giant papillary conjunctivitis and allergy, sterile ulcers, corneal warping, lens infection, protein and calcium deposits, lens fragility, and problems with disinfecting solutions. further long-term studies are needed to compare the safety of prolonged wear soft contact lenses with the safety of intraocular lenses, on which long-term studies are currently being done. | 1979 | 93736 |
| potentiation of the hepatotoxicity of carbon tetrachloride following preexposure to chlordecone (kepone) in the male rat. | | 1979 | 93792 |
| lack of dr antigens on human b-lymphocyte-mouse fibroblast hybrids that express hla-a,b antigens. | | 1979 | 93795 |
| in vitro primary immunization of human peripheral blood lymphocytes to klh: evidence for hla-d-region restriction. | | 1979 | 93813 |
| recent advances in applied malaria immunology. | our present knowledge of cellular and humoral factors which are involved in immunity to plasmodial infections are discussed. immunization against plasmodial infection has been achieved in birds, rodents, simians, and humans. avian hosts have been immunized against gametocytes which resulted in inhibition of gametocytes within the mosquito vector. immunization of humans against plasmodial gametocytes would indirectly protect them against malaria by blocking mosquito transmission to other suscepti ... | 1979 | 93828 |
| [allergenic properties of the blood serum of drug allergy patients]. | | 1979 | 93831 |
| antibody response against foot and mouth disease virus (fmdv). part ii: responses measured in fractionated sera of infected steers with complete virus, trypsin treated virus, 12 s virus subunits, via and heterologous virus. | | 1979 | 93833 |
| rna modulating specific and nonspecific immune responses. | | 1979 | 93861 |
| myelin basic protein treatment of experimental allergic encephalomyelitis in monkeys. | treatment of experimental allergic encephalomyelitis (eae) in two strains of monkeys with large amounts of myelin basic basic protein (bp) fails unless an adjunct is also used. in both strains the adjunct by itself is more effective than bp by itself, but in the one strain which could be investigated sufficiently, the combination can be made almost totally effective in reversing eae. the adjunct varies with the strain of monkey, an antibiotic in macaca mulatta and a steroid in macaca fasciculari ... | 1979 | 93874 |
| characterization and mode of action of a bacteriocin produced by a bacteroides fragilis strain. | a bacteroides fragilis strain produces a low-molecular-weight (13,500 to 18,700), proteinaceous bacteriocin during the stationary growth phase. the extracellular bacteriocin is not inducible by ultraviolet light or mitomycin c and is stable between ph 7.5 and 8.2. the majority of the bacteriocin is thermolabile, but a small proportion (3%) of the bacteriocin is stable after autoclaving at 121 degrees c for 15 min. killing of sensitive bacteroides cells follows single-hit kinetics, and the intera ... | 1979 | 93876 |
| receptive field organization in areas 17 and 18 of the cat [proceedings]. | | 1979 | 93893 |
| integration site of bovine leukemia virus dna in the bovine genome [proceedings]. | | 1979 | 93923 |
| identity and properties of multiple neuroleptic-binding sites in rat limbic brain areas [proceedings]. | | 1979 | 93926 |
| albumin synthesis in isolated hepatocytes of control and diethyl-nitrosamine-treated rats, maintained in suspension or in monolayer culture [proceedings]. | | 1979 | 93933 |
| semicarbazide-sensitive amine oxidase in rat aorta: a plasma-membrane enzyme [proceedings]. | | 1979 | 93954 |
| conversion of androstenedione to estrone in human fibroblasts cultured from prostate, genital and nongenital skin. | | 1979 | 94031 |
| demonstration of specific antigenecity of various fractions of human liver homogenate. | | 1979 | 94039 |
| effects of tamoxifen on the binding and metabolism of testosterone by human prostatic tissue and plasma in vitro. | the in-vitro metabolism of testosterone in benign and malignant prostatic tissue was examined and distinct quantitative differences between the two types of specimens were observed. the major metabolite of testosterone in the hyperplastic prostate was 5 alpha-dihydrotestosterone and a high 3 alpha(beta)-hydroxysteroid dehydrogenase activity was also detected. in the malignant tissue, 5 alpha-reductase activity was considerably reduced and there was little or no androstanediol formed; the 17 beta ... | 1979 | 94084 |
| isolation and characterisation of a strain carrying a conditional lethal mutation in the cou gene of escherichia coli k12. | a strain which carries a mutation conferring clorobiocin resistance and temperature sensitivity for growth was isolated from escherichia coli k12. genetic mapping and the molecular weight of the gene product suggest that the mutation is in the cou gene, specifying a sub-unit of dna gyrase. nuclear organisation and segregation and placement of septa are grossly abnormal in the mutant at 42 degrees c. rna synthesis and initiation of dna replication are also affected at the restrictive temperature ... | 1979 | 94144 |
| studies on fibronectin in the skin. iii. indirect immunofluorescence studies in lichen planus. | fibronectin is a glycoprotein which is responsible for a varity of functions in the human organism, such as mediation of contact between cells and between cells and fibres, opsonic qualities, interaction in the stabilization of fibrin, etc. fibronectin is an important constituent of the ground substance having a special affinity to collagen. in indirect immunofluorescence studies its presence has been abundantly demonstrated in normal human skin, in collagen-rich structures such as the basement ... | 1979 | 94206 |
| photolysis of mast cells in presence of protoporphyrin. | the effects of ultraviolet and visible irradiation in presence of protoporhyrin upon mast cells were investigated. rat peritoneal mast cells were suspended in a medium containing varying concentrations of protoporphyrin and were irradiated using a mercury vapor lamp. the release of histamine is related to both the concentrations of protoporphyrin and the period of irradiation. comparatively negligible amounts of histamine were released when the cells were irradiated in absence of protophyrin or ... | 1979 | 94207 |
| induction of delayed-type sensitivity to leishmania parasite in a case of leishmaniasis cutanea diffusa with bcg and cord-factor (trehalose-6-6' dimycolate). | the delayed hypersensitivity against the leishmania parasite was restored to a patient who had suffered from diffuse cutaneous leishmaniasis (dcl) for 26 years, by the application of an ointment containing heat-killed and lyophilized bcg and cord-factor (trehalose-6-6'-dimycolate) after stripping the affected and adjacent areas with scotch-tape. | 1979 | 94221 |
| a critical re-evaluation of the anisotropic index used in polarization microscopy: a study on epiphyseal cartilage. | topo-optical reactions specific for collagen and glycosaminoglycans were performed on epiphyseal cartilage plates which differed in age, in chemical composition, and in structure. retardation values were measured with the polarization microscope and anisotropic index values were calculated after each reaction. it was found that the anisotropic index proposed earlier for quantitative evaluation of topo-optical reactions did not refer either to the submicroscopic orientation pattern or to the quan ... | 1979 | 94227 |
| [vascularization of malignant melanoma in golden hamster]. | | 1979 | 94247 |
| biochemical and immunological studies of three genetic variants of 3-phosphoglycerate kinase 2 from the mouse. | three electrophoretic variants of 3-phosphoglycerate kinase 2 (pgk-2a,pgk-2b, and pgk-2c) were purified from dba/2j, c3h/hej, and c57l/j mice, respectively. pgk-2c exhibits only 2% of the specific activity of pgk-2a and pgk-2b in the reaction leading to the formation of 1,3-diphosphoglycerate. compared to pgk-2a and pgk-2b, pgk-2c exhibits broader coenzyme specificity and lower kms for substrate and coenzymes. incubation at 45c revealed immunionactivation and double immunodiffusion studies show ... | 1979 | 94263 |
| immunological approaches to chromatin and chromosome structure and function. | | 1979 | 94283 |
| natural plant enzyme inhibitors: part vii--alpha amylase inhibitors & amylases in plant tubers. | | 1979 | 94300 |
| crossed immunoelectrophoretic analyses of antigens from trypanosoma lewisi and trypanosoma musculi. | | 1979 | 94319 |
| chemotherapy of herpes simplex virus encephalitis in mice by direct intracerebral injection. | the effects of 9-beta-d-arabinofuranosyladenine-5'-phosphate (ara-a-5'-p) on herpes simplex virus encephalitis in mice were studied. this drug is a monophosphate derivative of adenine arabinoside (ara-a). when administered by the intracerebral (ic) route, ara-a-5'-p was highly effective in virus-infected mice in the 17-20 g weight range provided therapy was begun before clinical symptoms of encephalitis appeared. the most effective dose schedule was found to be three daily ic injections totaling ... | 1979 | 94338 |
| chlamydia psittaci: growth characteristics and enumeration of serotypes 1 and 2 in cultured cells. | the growth characteristics of chlamydia psittaci serotypes 1 and 2 (ovine and bovine origin) were studed in mouse l cells. formation of inclusions and yield of infectious progeny for serotype 1 were maximal when host cells were treated with cycloheximide and the ph in the cell culture medium was 7.2-7.4. the number of cells that contained inclusions and the infectivity yield for serotype 2 were maximal when the ph was 6.6-7.0. treatments with diethylaminoethyl dextran and cycloheximide increased ... | 1979 | 94339 |
| disopyramide plasma and myocardial tissue concentrations as they relate to antiarrhythmic activity. | antiarrhythmic concentrations of disopyramide in canine plasma and myocardium were determined by gas chromatography. ventricular tachycardia was incuded in anesthetized dogs by the intravenous administration of ouabain. disopyramide phosphate was then administered by a two-stage continuous infusion method. a rapid infusion of disopyramide (9.08 mg/kg/hr) was administered for 30 min, followed by a slow infusion (2.18 mg/kg/hr) to maintain steady-state plasma levels of 1.98-2.21, mean +/- sem = 2. ... | 1979 | 94410 |
| [study on the pathogenecity of chrysosporium species (author's transl)]. | | 1979 | 94426 |
| effect of subminimal inhibitory concentrations of mecillinam on the synthesis of dna, rna, and protein of salmonella typhimurium: a proposed mechanism of action. | salmonellae alter their rod-like morphology to become large ovals within 3-5 hr after being exposed to concentrations of mecillinam below the minimal inhibitory concentration. before this overt morphologic change occurs, synthesis of dna increases, with a concomitant decrease in total protein synthesis. incorporation of [3h]leucine into cell wall protein is markedly inhibited by mecillinam, whereas incorporation of leucine into soluble intracellular proteins is enchanced by the drug. electrophor ... | 1979 | 94451 |
| effects of subminimal inhibitory concentrations of ampicillin, chloramphenicol, and nitrofurantoin on the attachment of escherichia coli to human uroepithelial cells in vitro. | an in vitro system with epithelial cells of the human urinary tract and escherichia coli isolated from the urine of pateints with acute pyelonephritis was used for tests of the effect of antibacterial agents on bacterial adhesion. e. coli treated with subminimal inhibitory amounts of ampicillin attached less than untreated control bacteria. subminimal inhibitory amounts of chloramphenicol and nitrofurantoin had no effect on adhesion of the 15 strains of e. coli tested. the combination of bacteri ... | 1979 | 94452 |
| hereditary alpha 2-macroglobulin deficiency. | on screening of a normal material 1 man was found (age 37) who on repeated determinations had a low alpha 2m, namely 25 % with electroimmuno assay according to laurell. investigation of the family revealed that the mother (age 69) and one daughter (age 5) had low values too. all other coagulation and fibrinolytic components were normal. they had no signs of increased fibrinolysis and normal levels of alpha 2-antiplasmin, alpha 1-antitrypsin and antithrombin iii. liver function tests were normal. ... | 1979 | 94459 |
| endotoxin shock in the beagle dog. | | 1979 | 94472 |
| axonal transport. | | 1979 | 94473 |
| effect of silica on a culture of rat peritoneal macrophages. | | 1979 | 94527 |
| influence of substance p on mesenteric hemodynamics in the pig. | | 1979 | 94532 |
| a biochemical comparison of development of various facial bones in neonatal rats. | | 1979 | 94540 |
| placental alkaline phosphatase, alphafetoprotein and carcinoembryonic antigen in testicular tumors. tissue typing by means of cytologic smears. | indirect immunofluorescence and radioimmunoassay with specific rabbit antisera demonstrated the occurrence of alphafetoprotein (afp), carcinoembryonic antigen (cea) and placental alkaline phosphatase (plap) in primary testicular tumor cells. embryonal carcinomas had afp- and cea-containing cells, sometimes plap. plap and sometimes cea were found in seminoma cells. sera from patients with advanced non-seminomatous tumors could contain any of these antigens or any combination of them. sera from pa ... | 1979 | 94592 |
| studies on the role of vasopressin in blood pressure control of spontaneously hypertensive rats with established hypertension (shr, stroke-prone strain). | we investigated the role of arginine-vasopressin (avp) in maintaining the blood pressure of spontaneously hypertensive (sh) rats (stroke-prone strain) with established hypertension (22--28 weeks of age). in comparison with normotensive wistar kyoto (wky) rats, plasma avp concentrations of sh rats with benign hypertension (bh) were elevated twofold and in rats with severe or malignant hypertension (s-mh), fourfold. the height of the blood pressure was quantitatively related to plasma avp in both ... | 1979 | 94626 |
| transferable drug resistance of escherichia coli isolated from infant diarrhoea. | the resistance to several drugs was determined in 29 pathogenic strains of escherichia coli (026, 055 and 0111) isolated from infant diarrhoea and 18 non-pathogenic e. coli strains isolated from the same individuals. both pathogenic and nonpathogenic strains were resistant to at least 1 to 10 drugs, but only in four cases resistance patterns of the pathogenic strains were identical with those of non pathogenic ones. the majority of the strains were resistant to sulfonamide, tetracycline, ampicil ... | 1979 | 94745 |
| [comparative study of 5 alpha-reductase activity in the prostate and the human scalp]. | | 1979 | 94780 |
| study of the adriamycin-acidic phospholipid complex in model membranes [proceedings]. | | 1979 | 94796 |
| determination of metabolite compartition in hepatic cells by varying the redox state in vivo. | in the present study, metabolite (lactate, pyruvate, glycerol 3-phosphate, dihydroxyacetone phosphate) concentrations were measured in various redox states. the mathematical relations between metabolite concentrations in various redox states were expressed algebraically and studied. models which provided separate lactate/pyruvate (l/p) and glycerol 3-phosphate/dihydroxyacetone phosphate (g/d) spaces correspond to the experimental results in the case of "reductants" (e.g. ethanol, acetaldehyde, d ... | 1979 | 94822 |
| the influence of sex, of castration in new-born males and of androgen treatment in new-born females on the mouse-killing behaviour of the rat. | the results we have got on the mouse-killing behaviour of the rat point out the remarkable percentage difference between control males and control females, between integral males and males castrated at birth, and between normal females and females under the effects of androgens. such results make us believe that the appearance of the killer behaviour is affected by the presence of testosterone in the first days of life of the rat. | 1979 | 94825 |
| [faecal enzyme diagnostic (author's transl)]. | the hitherto existing results of determinations of enzymatic activities in stool are presented in this review. the chymotrypsin activity is diminished in advanced exocrine pancreatic insufficiency. the faecal alpha-amylase activity has up to now no significance in the diagnosis of pancreatic diseases. up to five amylolytic enzyme activities are detectable. the alkaline phosphatase is mostly of intestinal origin. up to 4 enzyme bands can be exhibited with the disc electrophoresis in polyacrylamid ... | 1979 | 94852 |
| [effect of ergoline derivatives on platelet and blood vessels]. | the influence of dihydrogenated ergot alkaloids on vessels and blood platelets was studied in vitro and in vivo. at low concentrations they cause contraction of isolated vein strips via a stimulation of alpha-adrenoceptors, at higher concentrations they antagonize the action of noradrenaline on arteries and veins and inhibit the adrenaline-induced platelet aggregation in vitro. in volunteers, intravenous and subcutaneous administration of dihydroergotamine (dihytamin) caused a decrease in blood ... | 1979 | 94864 |
| induction of monoclonal antibody synthesis in malignant human b cells by polyclonal b cell activators. relationship between b cell subsets and prognosis. | | 1979 | 94897 |
| a simplified short-term technique for detection of chemical carcinogens: microsomal degranulation by tannic acid. | | 1979 | 94904 |
| role of interferon in mice in protection against influenza a virus by bacterial ribosomes together with membranal glycoproteins of klebsiella pneumoniae as adjuvant. | nonspecific protection against infectious aerosols of influenza a virus was obtained in swiss mice after vaccination by aerosols of bacterial ribosomes together with membranal glycoproteins extracted from klebsiella pneumoniae as the adjuvant. it was shown that repeated stimulant aerosols were necessary to obtain this protection. routine estimation of serum interferon levels after administration of the association of ribosomes plus membranal glycoproteins to the animals by aerosol or intravenous ... | 1979 | 94908 |
| study of the interaction between phosphorylase and hydrophobic groups by means of affinity electrophoresis. | a homologous series of water-soluble alkyl-dextrans varying in the length of their hydrocarbon side-chain [-nh-(ch2)n-ch3; n = 1-5] were synthesized. when alkyl-dextrans were entrapped in polyacrylamide gel, the electrophoretic mobility of phosphorylase was retarded by hydrophobic interaction between phosphorylase and the immobilized alkyl groups. the dissociation constants of rabbit brain phosphorylase, rabbit skeletal muscle phosphorylase a and b and potato glycogen and starch phosphorylases w ... | 1979 | 94915 |
| chromatography of non-human albumins on cibacron blue-agarose. application to the separation of albumin from rat alpha-fetoprotein. | | 1979 | 94917 |
| [circadian variations of the plasma proteins in the adult male rat under natural synchronisation (author's transl)]. | circadian rhythms of blood total proteins, albumin, alpha 1-, alpha 2-, beta- and gamma-globulins were documented in 80 wistar spf adult male rats, synchronized by natural light (06.00-18.00 h) and darkness (18.00-06.00 h) during the month of october 78. blood was sampled at four fixed time points in the 24 h scale (i.e. 04.00, 10.00, 16.00 or 24.00 h). total proteins, albumin, alpha 2- and gamma-globulins showed a statistically significant rhythm with a maximum at 04.00 h. the data obtained in ... | 1979 | 94931 |
| [inhibition of rna synthesis in vitro by antibodies against mononucleotides]. | antibodies against purine nucleotides were obtained from rabbits immunized with conjugates of bovine serum albumine with amp or gmp. the antibodies purified by affinity chromatography on nucleoside monophosphate-human serum albumine-sepharose columns inhibited rna synthesis on native t4 phage dna by e. coli rna polymerase. the inhibition of transcription was due mainly to inhibition of the initiation stage of rna synthesis. | 1979 | 94937 |
| a silver carbonate method for cell counts of neurons and glial elements on paraffin embedded brain tissue. | a modification of the del rio-hortega method for the demonstration of central nervous system elements is presented. this silver impregnation technique is particularly useful for the classification of cell types for quantitative differential cell counts. formalin fixed paraffin sections are immersed in formol-ammonium bromide for 1 1/2 hours; this solution is an excellent mordant for various silver nitrate stains. the samples are stained for 20 to 60 minutes in a silver carbonate solution (25 ml ... | 1979 | 94949 |
| [the behaviour of some histochemical reactions in testicle tissue of a white rat as a result of kaptan action (author's transl)]. | | 1978 | 94984 |
| properties and usefulness of the original k-562 human myelogenous leukemia cell line. | | 1979 | 95026 |
| projections of raphe neurones to the cerebellar vermis cortex in the rabbit. a horseradish peroxidase (hrp) study. | | 1979 | 95045 |