| characterization of the purified components of a new homologous series of alpha-mycolic acids from mycobacterium tuberculosis h37ra. | homologous series of alpha-mycolic acids from mycobacterium tuberculosis h37ra were separated according to size as their p-bromophenacyl ester by bonded c18 reverse-phase, high performance liquid chromatography. mass spectrometry of the prominent components separated by high performance liquid chromatography gave relatively simple spectra and showed a series of components differing by 28 atomic mass units. a total of different structures were identified. the structures were established as follow ... | 1978 | 97292 |
| amino acid sequence of beta-galactosidase. viii. sequence of the nh2-terminal segment, cnbr peptides 1 to 9, residues 1 to 377. | the amino acids in 9 cyanogen bromide peptides have been placed in sequence starting from the nh2 terminus. the peptides account for residues 1 to 377 of the whole protein and include the largest (cnbr7, 119 residues) and the smallest (cnbr1, 2 residues) of the cyanogen bromide peptides. this region contains only 3 of the 20 lysine residues in the polypeptide chain. a high proportion of charged groups are present (28 of 66 arginine, 28 of 60 glutamic acid, and 24 of 65 aspartic acid residues). | 1978 | 97295 |
| immunochemical studies of the inactivation of aspartate transcarbamylase by stationary phase bacillus subtilis cells. evidence for selective, energy-dependent degradation. | the aspartate transcarbamylase of bacillus subtilis is stable in exponentially growing cells, but undergoes rapid, energy-dependent inactivation when growth is inhibited by nutrient depletion or addition of antibiotics or other inhibitors of metabolism. this inactivation has been analyzed by a variety of immunochemical techniques, including direct and indirect immunoprecipitation of extracts of cells labeled with 3h-amino-acids, microcomplement fixation, and neutralization of enzymatic activity. ... | 1978 | 97299 |
| folate analogues altered in the c9-n10 bridge region: n10-toxylisohomofolic acid and n10-toxylisohomoaminopterin. | | 1978 | 97383 |
| preliminary x-ray crystallographic data on phospholipase c from bacillus cereus. | | 1978 | 97390 |
| transient pseudomonas bacteremia in a heroin addict. resemblance to right-sided endocarditis. | | 1978 | 97401 |
| neonatal gonococcal orogastric contamination. | | 1978 | 97404 |
| [results of early nutrition of newborn infants with low birth weight. ii. effects of early nutrition on bilirubin metabolism of newborn infants with birth weights from 1501 to 2000 g]. | | 1978 | 97464 |
| unique behavioral effects of beta endorphin and their relationship to thermoregulation and hypothalamic function. | | 1978 | 97480 |
| increased vasodepressor effect of prostaglandins a1 and e1 in renal hypertensive rabbits. | | 1978 | 97482 |
| the preparation and use of antibodies as diagnostic biochemical probes. | | 1978 | 97493 |
| [multiplication of bdellovibrio bacteriovorus in the cytoplasm of the bacterial host]. | the bacterial parasite bdellovibrio bacteriovorus was studied in the process of its interaction with the host bacterium pseudomonas fluorescens. as has been shown by time-lapse microcinematography, along with the normal growth of b. bacteriovorus in the periplasmatic space of the host bacterium, occasionally (4--5%) the parasite is located in the cytoplasm where the complete stage of its intracellular growth takes place with the release of progeny. | 1978 | 97504 |
| malignant transformation of a mouse epithelial cell line with polycyclic aromatic hydrocarbons. | | 1978 | 97564 |
| [sensitivity of bacteria to antibiotics. evaluation of a rapid automatic method (author's transl)]. | a rapid automated sensitivity testing system is evaluated in this report. the results have been compared with the standard disk diffusion method (ics). three hundred strains recently isolated from clinical cases : enterobacteriaceae, staphylococcus aureus, streptococci d, pseudomonas aeruginosa, have been tested. the general agreement between the two techniques was 89 p. cent. | 1978 | 97613 |
| [method of rapid determination of the cord factor in the mycobacterium colonies on solid nutrient medium]. | | 1978 | 97660 |
| bromocriptine, dihydroergotoxine, methysergide, d-lsd, cf25--397, and 29--712: effects on the metabolism of the biogenic amines in the brain of the rat. | | 1978 | 97702 |
| [reservoirs and wild vectors of trypanosoma cruzi. lxviii: infection of mammals by oral route]. | | 1978 | 97735 |
| [effect of chlorfenvinfos and carbaryl on calcium and phosphorus metabolism in rat skeleton. ii. in vitro studies]. | | 1978 | 97769 |
| neurotoxicity of adriamycin (doxorubicin) perfused through the cerebrospinal fluid spaces of the rhesus monkey. | | 1978 | 97803 |
| the pattern of sporulation in anabaena circinalis and comments on the role of heterocysts in sporulation in blue-green algae. | cells between two intercalary heterocysts differentiate at random into spores in a. circinalis. one or more cells, which fail to transform into spores, are present between the two adjacent spores, and these cells disorganize later. a critical c:n ratio regulates sporulation and heterocyst formation. during sporulation the reductive ability of the heterocyst gradually diminishes. it is concluded on the basis of this and other evidence that sporulation is regulated by interactions between heterocy ... | 1978 | 97869 |
| [immunological study of cellular components of pseudomonas aeruginosa. iv. fractionation of pseudomonas aeruginosa mucus by diafiltration and biological properties of isolated fractions]. | in fractionation of pseudomonas aeruginosa mucus (strains no. 8 and 1463) by means of diafiltration on the system of membranes diaflo xm-300, xm-100a, pm-30, and pm-10 there was obtained a successive series of fractions differing by the molecular weight and chemical composition. according to the results of gel chromatography fractions with the mol wt of 100000 dalton and over apparently represented protein-polysaccharide components of mucus in the form of complexes; fractions with the mol wt of ... | 1978 | 97882 |
| the histochemistry of mucosubstances in ferret salivary glands. | the mucosubstances of the major salivary glands of the ferret were analysed using different histochemical reactions. almost all the parotid acinar cells had sialic acid-containing mucus. there were a very few cells, the granules of which gave reactions for sulphated mucins. submandibular gland mucus was sulphated in the major parts of the gland. there were occasional cells which gave reactions to carboxylated mucin. the sublingual and the molar glands had tubules which had 2 types of mucous cell ... | 1978 | 97904 |
| [enzyme-histochemical behaviour of the tanycyte ependyma in the iii. ventricle of the rat with thiamin deficiency (author's transl)]. | the influence of experimental thiamine deficiency in rats on enzyme-histochemical parameters was carried out in the diencephalon. the degree of thiamine deficiency was measured by the activity coefficient of transketolase in the red blood cells. the alpha-etk of thiamine deficient animals was 1,45 +/- 0,36, of equal-fed animals 1,04 +/- 0.04 and of control animals 1,08 +/- 0,04. we got the following results: lactatdehydrogenase, acid phosphatases and thiamine pyrophosphatase did not indicate any ... | 1978 | 97912 |
| activity of three 8-hydroxyquinoline derivatives against in vitro dental plaque. | three 8-hydroxyquinoline derivatives, assessed using an in vitro preformed dental plaque model system, were differentially inhibitory for four plaque-forming microorganisms. | 1978 | 98105 |
| [food additives and their possible genetic toxicity; microbiological determination]. | in the present work we intend to find an accurat methodology to establish in an easy way the mutagenic potential of drugs employed as food additives. for that purpose we first selected a microbiological system for performing this assay. the method assayed consisted of investigating the effect exerted on genetic recombination by the following chemical agents: chloroacetic acid, iodoacetic acid, sorbic acid, potassium metabisulfite, sodium nitrite, auramine and erythrossine. the activity of these ... | 1977 | 98122 |
| effects of various divalent cations on the survival of neisseria gonorrhoeae in liquid media. | the effect of various concentrations of divalent cations on survival of gonococci in liquid medium was studied. the growth of neisseria gonorrhoeae was inhibited by manganous chloride in concentrations above 1 x 10(-5)mol/l while the growth of control organisms such as neisseria meningitidis and escherichia coli was not inhibited by the same salt even at 1 x 10(-2)mol/l. copper sulphate, cobaltous nitrate, nickel chloride, and zinc sulphate also had deleterious effects on gonococci. magnesium ch ... | 1978 | 98204 |
| characteristics of pr5, a lipid-containing plasmid-dependent phage. | an extensive characterization of plasmid-dependent phage pr5 isolated from sewage has been carried out. the phage has a head diameter of 65--68 nm, is isometric with a double-layered capsid, and a minority possess tails. it adsorbs to many but not all types of bacteria possessing p, n, or w plasmids. the phage contains 20% lipid, 15.1% dna, and 64.9% protein by weight and has a buoyant density of 1.265 g/ml in cscl. the dna is double-stranded with a g + c content of 49% and a molecular weight of ... | 1978 | 98225 |
| cellular uptake, transport, and macromolecular binding of benzo(a)pyrene and 7,12-dimethylbenz(a)anthracene by human cells in vitro. | | 1978 | 98231 |
| thyroid-stimulating hormone: neuroregulation and clinical applications. part 2. | | 1978 | 98254 |
| ultrastructural hepatic changes by carbamate pesticide (sevin) in rats. | | 1978 | 98323 |
| passive immunization with an antibody to the beta-subunit of ovine luteinizing hormone as a method of early abortion--a feasibility study in monkeys (macaca radiata). | antiserum to the beta-subunit of ovine luteinizing hormone (olh-beta) raised in monkeys (macaca radiata) has been tested by a variety of criteria both in vivo and in vitro to establish its ability to neutralize olh, hlh, and human chorionic gonadotropin (hcg). passive administration of this antiserum caused inhibition of ovulation and termination of pregnancy in recipient monkeys as indicated by premature vaginal bleeding and a significant reduction in serum progesterone and estrogen levels. the ... | 1978 | 98358 |
| pre-immunization and post-exposure treatment with inactivated rabies vaccine of chick embryo cell culture origin (cec). | routine laboratory assay revealed that the potency of concentrated rabies vaccine of chick embryo cell culture (cec) origin was in the same level compared with suckling mouse brain (smb) vaccine. over one hundred persons received two doses of cec vaccine at an interval of one week and produced high level of neutralizing antibody against rabies virus. the monkeys experimentally infected with street rabies virus were satisfactorily protected by subcutaneous inoculation with cec vaccine one hour af ... | 1978 | 98373 |
| comparative effect of spironolactone and hydrochlorothiazide therapy in experimental renal hypertension of rhesus monkeys. | | 1978 | 98439 |
| formylation of initiator trna methionine in procaryotic protein synthesis: in vivo polarity in lactose operon expression. | eucaryotic and procaryotic organisms differ in two aspects of their translation machinery: polycistronic messengers are expressed as a sequence of individual proteins only in procaryotes, and the initiation of protein synthesis proceeds with an initiator trna which is found to be modified (formylated) in procaryotes and not in eucaryotes. in the present study, we show that formylation is required in vivo for the coordinate expression of the escherichia coli lactose operon. our experiments are co ... | 1978 | 98518 |
| altered mrna metabolism in ribonuclease iii-deficient strains of escherichia coli. | the metabolism of mrna from the lactose (lac) operon of escherichia coli has been studied in ribonuclease (rnase) iii-deficient strains (rnc-105). the induction lag for beta-galactosidase from the first gene was twice as long, and enzyme synthesis was reduced 10-fold in one such mutant compared with its isogenic rnc+ sister; in the original mutant strain ab301-105, synthesis of beta-galactosidase was not even detectable, although transduction analysis revealed the presence of a normal lac operon ... | 1978 | 98520 |
| identification of low chlorinated biphenyls in human milk by gas chromatography--mass spectrometry. | trichlorobiphenyl and tetrachlorobiphenyls in human milk were analysed by gas chromatography--mass spectrometry and mass fragmentography using silicone ov-1 and apiezon l grease as stationary phases. low-chlorinated biphenyls had been considered to be excreted rapidly from the body, but in this work quantities of tri- and tetrachlorobiphenyls amounting to approximately 30% of the total of polychlorinated biphenyls (pcbs) accumulated in the milk were identified. this result is important in relati ... | 1978 | 98535 |
| immunization with dextransucrases, levansucrases, and glycosidic hydrolases from oral streptococci. ii. immunization with glucosyltransferases, fructosyltransferases, and glycosidic hydrolases from oral streptococci in monkeys. | the feasibility of immunizing monkeys with enzymes from oral streptococci in an attempt to reduce dental caries was investigated. forty rhesus monkeys, macaca mulatta, were used. cariogenic streptococci, s mutans, were implanted into all the monkeys' mouths. there was no pathological effect resulting from immunization. of the 40 animals, 30 retained the implanted flora throughout the experiment; the remaining 10 were reimplanted until the streptococci remained. in six months, gross carious lesio ... | 1977 | 98540 |
| antigen-induced neutrophil chemotactic activity in man. correlation with bronchospasm and inhibition by disodium cromoglycate. | we have previously reported increased neutrophil chemotactic activity in sera obtained after positive antigen inhalation responses in atopic subjects. this report describes the kinetics of appearance of this serum activity and the effects of antigen dose and disodium cromoglycate pretreatment on the response in 10 ragweed-sensitive subjects. significantly increased chemotactic activity was present as early as 1 min, peaked at 10 min, and persisted through 24 hr after inhalation of antigen. the i ... | 1978 | 98551 |
| allogeneic restriction of acquired antimicrobial resistance in the rat. | allogeneic restriction of acquired antimicrobial resistance was demonstrated by infusing listeria-immune thoracic duct lymphocytes (tdl) into syngeneic, semisyngeneic, or allogeneic recipients that had been infected i.v. with listeria monocytogenes (lm). syngeneic and semisyngeneic recipients enjoyed a high level of protection (3 to 5 log10 reduction in viable organisms within 64 hr, whereas allogeneic recipients were poorly protected (0.5 to 2.5 log10 reduction). sharing one haplotype between t ... | 1978 | 98584 |
| cricket paralysis virus and drosophila c virus: serological analysis and comparison of capsid polypeptides and host range. | | 1978 | 98592 |
| circadian variations in cortisol concentrations in the plasma of female rhesus monkeys. | | 1978 | 98605 |
| a microagglutination test for yersinia enterocolitica infection: recognition of multiple serotypes in experiments with stained suspensions of serotype o5,27. | when suspensions of yersinia enterocolitica were stained with triphenyl-tetrazolium chloride (ttc) their antigenic specificity, as determined by tube and microtitre-plate agglutination tests, was altered. thus, a ttc-stained suspension of serotype o5,27 detected antibodies to nine o serotypes of y. enterocolitica in sera from experimentally infected animals but did not cross-react with antisera to organisms of five other unrelated genera including brucella. the same suspension did, however, cros ... | 1978 | 98635 |
| observations on acute gastric dilatation in nonhuman primates. | in the years 1967-1977 we diagnosed 23 cases of acute gastric dilatation in monkeys. fourteen of these animals were macaca mulatta, five macaca fascicularis, and one each of macaca nemestrina, aotus trivirgatus, saimiri sciureus, and colobus guereza. fourteen of the animals were males, nine were females, and all were adults or subadults. mortality was 78% (18 of 23 animals). thirteen of the animals had received on anesthetic, immobilizing, or tranquilizing drug 1-2 days before developing acute g ... | 1978 | 98666 |
| experimental injury of the optic nerve with optic disc swelling. | an ultrastructural study utilizing horseradish peroxidase was performed to determine the mechanism and consequences of leakage of vascular protein following injury of the optic nerve. unilateral optic nerve injuries were produced in four rhesus monkeys by making a cautery lesion on the retrobulbar portion of the optic nerve. optic disc changes were followed with stereo fundus photography and fluorescein angiography. three to 14 days after injury horseradish peroxidase was given intravenously and ... | 1978 | 98667 |
| who pays health costs of alcohol and tobacco? | | 1978 | 98713 |
| the effects of sodium nitroprusside and trimethaphan camsylate on cerebral blood flow in rhesus monkeys. | hemispheric cerebral blood flow was measured in the rhesus monkey before and after infusion of the hypotensive agents sodium nitroprusside and trimethaphan camsylate. the intracarotid injections of 133xe was utilized, and flow was calculated by the "flow initial" technique. cerebral blood flow did not change significantly with the administration of trimethaphan camsylate. however, with a small reduction in blood pressure (10.6%) during the administration of sodium nitroprusside, the cerebral blo ... | 1978 | 98729 |
| electron-microscopic identification of axonal initial segments belonging to interneurons in the dorsal lateral geniculate nucleus of the monkey. | | 1978 | 98733 |
| effect of dopamine on renal blood flow of baboon in endotoxin shock. | renal vasodilation observed in canine endotoxemia did not occur during endotoxin shock in the baboon: in fact, renal artery blood flow was markedly reduced. infusion of dopamine in the baboon restored the renal artery blood flow. | 1978 | 98752 |
| studies on the occurrence of peptococcus indolicus and corynebacterium pyogenes in abscesses in swine, and on the occurrence of pc. indolicus in apparently normal skin and mucous membranes of piglets. | pc. indolicus was isolated from 42.7% and cb. pyogenes from 48.7% of 150 pus-samples from abscesses in pigs (slaughter-house material, table i). in 41 specimens the two organisms were found together. further, pc. indolicus was demonstrated in 22.4% of 290 swabs from apparently normal skin and mucous membranes of piglets (autopsy material, table ii). by gel diffusion analysis the strains of pc. indolicus were referred to the serotypes b, c, d, e, or f. the type distribution (table iii) possibly r ... | 1978 | 98755 |
| critical factors in the quality control of antilymphocyte globulin (alg). | | 1977 | 98763 |
| location of the genes for human heavy chain immunoglobulin to chromosome 6. | immunoglobulin synthesis was examined in 31 man-mouse hybrid clones produced by fusing rag mouse cells with human lymphoid cells. cells were grown in serum-free medium containing [(14)c]leucine and a (14)c-labeled amino acid mixture. spent medium was dialyzed, concentrated, and subjected to radioimmunoelectrophoresis. eighteen clones were found to produce material that gave a radiolabeled precipitin line with anti-human igg (gamma-chain specific). production of material which was indistinguishab ... | 1978 | 98768 |
| [infection of alouatta carayá (mono aullador) by junín virus]. | | 1978 | 98811 |
| differentiation of mycobacteria by "in vivo" and "in vitro" delayed hypersensitivity reactions. | guinea pigs were sensitized with heat killed m. tuberculosis, m. kansasii, m. scrofulaceum, and m. avium-intracellulare. purified protein derivatives (ppds) prepared from each of these organisms were tested for delayed type hypersensitivity by lymphocyte transformation, macrophage migration, and mantoux type skin sensitivity tests. the homologous reactions were consistently more intense than heterologous reactions in all three procedures. the skin test procedure was more sensitive than either in ... | 1978 | 98814 |
| [heterologous transformation: search for an explantation of the high effectiveness of bacillus subtilis transformation achieved by using bacillus natto dna]. | a higher efficiency of b. subtilis cells transformation by b. natto dna is true for every concentration of dna and is not due to the helping effect known for streptococci, strain challis. in competition experiments for dna uptake unlabelled b. natto and b. subtilis dnas when added to transforming h3-dna reduced the radioactivity of the samples by a factor of three and two, respectively. a conclusion is drawn that a higher rate of b. natto dna penetration to the b. subtilis cells results in a hig ... | 1978 | 98872 |
| [dynamics of changes in the surface of normal cultivated rat cells after a single exposure to the carcinogen 7,12-dimethylbenz(a)anthracene]. | changes in the cell surface after a single treatment with 7,12-dimethylbenz(a)anthracene (dmba) of newborn rat carcass in cell culture have been studied by means of the agglutination reaction with concanavalin a. dmba was shown to cause alterations in the cell surface. at 0.5 mkg/ml of dmba, the difference in agglutinability of treated and untreated cells persists for 30 days. at 0.1 mkg/ml of dmba, the agglutinability of drug-treated and control cells was similar on the 4th day after removal of ... | 1978 | 98876 |
| [some aspects relating to the aflatoxin generation during the self-heating of cereals]. | in a stored batch of grain which was already affected by mould-formation tests were carried out with the known aflatoxin producer aspergillus flavus. a significantly lower aflatoxin production ensued if the mould growth was not connected with self-heating of the stored product. however, in conformity with increasing mould formation the germinating power was adversely affected and the significant signs (fatty acid number, reductive and none-reductive sugars) were influenced in the grain, irreleve ... | 1978 | 98933 |
| age-associated changes in the blood picture of the goat. | | 1978 | 98936 |
| interferon inducing activity of polyinosinic acid. | although poly(i) is generally considered to be inactive as an interferon inducer, we have found several authentic poly(i) preparations to be effective inducers. their interferon inducing ability varied considerably from one cell system to another. in human diploid fibroblasts, primed with interferon and superinduced by cycloheximide and actinomycin d, all active poly(i) samples proved nearly as effective in inducing interferon as poly(i).poly(c). in primary rabbit kidney cell cultures, the activ ... | 1978 | 99486 |
| radioautographic study of 5-hydroxytryptamine-containing nerve terminals in central ganglia of planorbis corneus: comparison with other species and characteristics of the serotoninergic nerve terminal. | central ganglia from planorbis corneus were incubated with [3h]5-hydroxytryptamine and [3h]-leucine. after fixation, sections were examined by light and electron microscopic autoradiography. with [3h]5-hydroxytryptamine there was a high level of uptake into a small number of axons and terminal processes in the neuropil. the terminal processes contained granular vesicles (diameter 50--120 nm), some of which possessed eccentrically placed cores, and agranular vesicles (mean diameter 60 nm). no mem ... | 1978 | 99497 |
| [salmonella infections]. | | 1978 | 99539 |
| [transplantation of langerhans' islands]. | | 1978 | 99549 |
| the effects of foveal prestriate and inferotemporal lesions on matching to sample behaviour in monkeys. | | 1978 | 99683 |
| behavioral measurement measurements of excitability changes in reward sites in the dog: a frequency dependent effect. | | 1978 | 99757 |
| effects of entrapment in liposomes on the distribution, degradation and effectiveness of methotrexate in vivo. | | 1978 | 100041 |
| [method of determining the antimicrobial activity of alcohol extracts of propolis]. | it is proposed to determine the antimicrobial activity of propolys alcohol extracts by the method of subsequent dilutions in solid nutrient media. dilution of the extracts immediately in hot agar eliminated the inhibiting effect of the extragent on the microbial growth. opalesence appearing in the agar did not prevent estimation of the results in contrast to the method of subsequent dilutions in liquid nutrient media. | 1978 | 100047 |
| modified peptidoglycan transpeptidase activity in a carbenicillin-resistant mutant of pseudomonas aeruginosa 18s. | a carbenicillin-resistant mutant of pseudomonas aeruginosa 18s was found to possess peptidoglycan transpeptidase activity significantly more resistant to inhibition by benzyl penicillin, ampicillin, carbenicillin, and cephaloridine than that of the parent strain. the mutant was more resistant than the parent strain to all of the beta-lactam antibiotics tested, and 50% inhibition values for these compounds against membrane-bound model transpeptidase activity paralleled this increase. the resistan ... | 1978 | 100051 |
| [delayed implantation and early developmental defects in the mouse caused by pcb: 2,2'-dichlorobiphenyl (author's transl)]. | pregnant mice administered per os during the days 1--3 (plug day = day 0) post conception (p.c.) with 375 mg 2,2'-dichlorobiphenyl/kilograms/day revealed on day 18 p.c. increased number of resorptions and doses up from 500 milligrams/kilograms/day led to a substantial retardation of the prenatal development. based on the investigations during the early development it is concluded, that retardation of the fetus is caused by a delayed implantation. it is assumed, that increased resorption is due t ... | 1978 | 100080 |
| cooperative binding of mn2+ and non-cooperative binding of mg2+ to beta-galactosidase (e. coli). | | 1978 | 100107 |
| preparation and properties of a phospholipid-free form of microsomal udp-glucuronyltransferase. | | 1978 | 100135 |
| [origin of a mitogrenic factor for cultivated macrophages (imf: inflammatory mitogenic factor) found in exudates of non-specific acute inflammation]. | the mitogenic activity of inflammatory exudate obtained from irradiated rats is reduced. after transfer of bone marrow syngeneic cells into irradiated rats this mitogenic activity is further decreased, while after transfer of thymic cells it is increased. it is postulated that the mitogenic activity of inflammatory exudate could be related to thymic cells and that t lymphocytes may be involved in non specific-inflammatory reactions. | 1978 | 100246 |
| molecular structure of the teichuronic acid of bacillus megaterium. | | 1978 | 101233 |
| antigenicity of purified glutaraldehyde-treated cholera toxoid administered orally. | the antigenicity of orally administered glutaraldehyde-treated cholera toxoid was investigated in healthy volunteers. fourteen volunteers ingested two or three 2-mg doses of toxoid with saline, with the doses spaced at 28-day intervals. thirteen other volunteers received comparable toxoid doses with nahco3 and milk to neutralize gastric acid. increments in circulating antitoxin levels were used to assay the antigenicity of oral toxoid. antitoxin was measured by adrenal cell, rabbit skin permeabi ... | 1978 | 101456 |
| isolation of ekatetrone, a new metabolite of producing variants of streptomyces aureofaciens. | from a mixture of substances formed by producing strains of streptomyces aureofaciens under conditions of submerged fermentation a new metabolite, ekatetrone, was isolated. its isolation and basic physical and chemical data are described. ekatetrone is a quinone derivative with a carboxamide group. in tests in vitro with cells of ehrlich's ascites tumour evidence was provided that ekatetrone inhibits proteo- and nucleosynthesis. | 1978 | 101501 |
| one-carbon metabolism in methanogenic bacteria: analysis of short-term fixation products of 14co2 and 14ch3oh incorporated into whole cells. | methanobacterium thermoautotrophicum, m. ruminantium, and methanosarcina barkeri were labeled with 14co2 (14co2 + h14co3- + 14co32-) for from 2 to 45 s. radioactivity was recovered in coenzyme m derivatives, alanine, aspartate, glutamate, and several unidentified compounds. the properties of one important structurally unidentified intermediate (yellow fluorescent compound) displayed uv absorbance maxima at ph 1 of 290 and 335 nm, no absorbance in the visible region, and a fluorescence maximum at ... | 1978 | 101522 |
| linkage map of pseudomonas aeruginosa pat. | the locations of new markers relative to markers previously mapped on the chromosome of pseudomonas aeruginosa strain pat were defined by generalized transduction with phage f116l and f1083. although the marker orders of the various marker groups were deduced mainly from the results of two-factor crosses, the locations of a number of markers were confirmed by three-factor crosses. a linkage map of the chromosome of p. aeruginosa pat was constructed which shows the relative locations of 50 genes. ... | 1978 | 101525 |
| synthesis and salvage of purines during cellular morphogenesis of myxococcus xanthus. | intact cells of myxococcus xanthus were examined for de novo purine synthesis and salvage utilization. the cellular uptake rates of radioactive glycine (de novo purine precursor), adenine, and guanine were measured, and thin-layer chromatography and radioautography were used to examine cell extracts for de novo synthesized purine nucleotides. intact vegatative cells, glycerol-induced myxospores, and germinating cells of m. xanthus cw-1 were able to carry out de novo purine and salvage synthesis. ... | 1978 | 101526 |
| chromosome-membrane association in bacillus subtilis. iv. further purification of dna-membrane complex by using a combination of centrifugation and electrophoresis. | we have developed a simple procedure to purify a dna-membrane complex from bacillus subtilis by using a combination of centrifugation and electrophoresis. several unique proteins were detected in the purified complex. | 1978 | 101532 |
| peptide hydrolases of lactobacillus casei: isolation and general properties of various peptidase activities. | discovery of an endopeptidase by gel chromatography and separation of 3 exopeptidases (a dipeptidase, an aminopeptidase and a specific carboxypeptidase) from lactobacillus casei ncdo 151 by affinity chromatography is described. the 3 exopeptidases were strongly inhibited by the metal chelators edta and 1,10-phenanthroline but were reactivated with co2+ and mn2+. the ph optima for aminopeptidase, dipeptidase and carboxypeptidase activities were 6.5, 7.6 and 7.2, respectively. maximum activity was ... | 1978 | 101561 |
| incorporation of amino acids by isolated submitochondrial fractions of lactating goat mammary gland in vitro. | incorporation of amino acids by mitochondria and its subfractions from mammary gland of the goat during lactation was studied in vitro. assessment of distribution of radioactivity incorporated by intact mitochondria into its subfractions revealed maximum specific activity in the inner membrane. during lactation the inner membrane of mitochondria exhibited further stimulation in such incorporation. matrix was the next active fraction whereas outer membrane and peripheral space had negligible radi ... | 1978 | 101564 |
| [studies on moraxella. i. a new selective medium for moraxella sp. (author's transl)]. | | 1977 | 101603 |
| [epidemiological study on beta hemolytic streptococci among healthy school children in toda city, saitama (author's transl)]. | | 1978 | 101618 |
| [clinical studies of childhood empyema experienced for the past 12 years (author's transl)]. | | 1978 | 101626 |
| growth and hematologic development of the patas monkey (erythrocebus patas) to one year of age. | data from 338 blood samples of 31 patas monkeys is presented to show the normal hematolgoic development from birth to one year of age, and is compared to 120 samples from normal adults. marked changes in hematocrit, hemoglobin, red cell numbers, and leukocyte distribution which occurred during the first month were followed by a slow progression to adult values. body weight data is also presented which shows a linear growth rate during the first year of life. | 1978 | 101669 |
| dominant constitutive mutations in malt, the positive regulator gene of the maltose regulon in escherichia coli. | | 1978 | 101676 |
| clinical studies on pipemidic acid. | | 1978 | 101691 |
| [exocrine gland activities and the kinin system]. | | 1978 | 101694 |
| preparation of nitrogenase. | | 1978 | 101737 |
| effect of certain sulphydryl compounds and dimethyl sulphoxide on potassium release by certain amines and proteins from pseudomonas aeruginosa. | dithiothreitol, cysteine, and mercapto-ethanol inhibit k+ release from cells of pseudomonas aeruginosa by amines and nh4cl incubated at ph 8.5. the inhibitions are competitive for the monamines and nh4cl but non-competitive for the diamines and spermidine. the percent inhibition is largest for tryptamine, least for spermidine and ethylene diamine. dmso inhibits k+ release by monamines and certain proteins but not significantly by diamines and histamine. the inhibitions are competitive. | 1977 | 101739 |
| oxygen requirement for prostaglandin biosynthesis. | the formation of prostaglandins by vesicular gland cyclooxygenase can be regulated by o2 concentrations below 30 micron (20 mm hg) with an apparent km value of about 5 micron. this result suggests that most mammalian tissues might be expected normally to have sufficient o2 for some synthesis, and that only occasionally, would the level of oxygen available within some tissues become marginally inadequate to sustain a high rate of prostaglandin biosynthesis. | 1978 | 102002 |
| [initiation of germination of clostridium difficile spores by lysozyme]. | the germination rate of spores of c. difficile which is usually lower than 10(-5) is raised to about 5.10(-3) in presence of lysozyme. all spores are initiated by lysozyme when previously treated by sodium thioglycolate. these spores are indeed lysozyme-dependent for germination. | 1978 | 103645 |
| [effect of lymphokines produced in a grafted system on production of prostaglandins by macrophages]. | mice peritoneal macrophages cultured in vitro release a prostaglandin-like activity as evaluated by a bio-assay using rat stomach fundus. the prostaglandin release is greatly increased when macrophages are incubated with the supernatant of mixed lymphocyte cultures between recipient and donor of a skin allograft. this phenomenon was found in all strains of mice tested except c3h/hej mice, a strain already known for its defective responsiveness to bacterial lipopolysaccharide (lps). | 1978 | 103646 |
| [epileptogenic action of intra-amygdaloid injection of kainic acid]. | intra-amygdaloid unilateral application of low doses of kainic acid rapidly elicits, in both chronic and acute conditions, secondarily generalized convulsive seizures which often culminate in fatal true status epilepticus unless appropriate anti-epileptic drugs are provided. spontaneous recurrent seizures are observed for several hours starting approximately 10 min. after the application of kainic acid. in addition to the primary degeneration in the amygdaloid complex, a secondary cell loss is s ... | 1978 | 103652 |
| evaluation of polymer flock and metal alloy intra-tubal device in pigtail monkeys. | two intratubal devices, one covered with a flock made from ethylene vinyl acetate and the other constructed of titanium-aluminum-vanadium alloy with an etched surface were evaluated after being placed in the fallopian tubes of pigtail monkeys. in some instances, the devices were medicated with 10% silver nitrate or 50% quinacrine hydrochloride. the microflock device anchored in the tube mechanically, but there is no evidence that either the polymeric or metal alloy device formed an actual attach ... | 1978 | 103682 |
| toxoplasma gondii: penetration into differentiating friend erythroleukemia cells. | | 1978 | 103745 |
| plasmodium: experimental animals for human malaria and research needs. a review. | | 1978 | 103748 |
| a receptor for polymerized human and chimpanzee albumins on hepatitis b virus particles co-occurring with hbeag. | a receptor for polymerized human serum albumin was demonstrated on dane particles as well as on 20-nm hepatitis b surface antigen particles, isolated from asymptomatic carriers of hepatitis b virus who were positive for hbeag. in contrast, such receptor was not born by 20-nm hepatitis b surface antigen particles obtained from carriers positive for antibody to hbeag. hepatitis b surface antigen particles with the receptor were heavier than those without, and when treated with pronase, they became ... | 1979 | 103774 |
| dietary lactose and the aetiology of human small-intestinal hypolactasia. | | 1978 | 103781 |
| high affinity uptake sites for taurine in the retina. | | 1978 | 104877 |
| non-immunological regression of dimethylbenz(a) anthracene-induced experimental keratoacanthomas in the rabbit. | in 9 rabbits, with a total of 17 experimental keratoacanthomas, a search has been made for immune-mediated mechanisms which could possibly be involved in the spontaneous regression of these tumours. immunofluorescence studies did not reveal significant staining patterns. with skin tests, using autologous extracts prepared in three different ways, no delayed cutaneous hypersensitivity reactions were observed. | 1979 | 104893 |
| effect of auranofin, a new antiarthritic agent, on immune complex-induced release of lysosomal enzymes from human leukocytes. | auranofin, an oral chrysotherapeutic agent effective in the treatment of rheumatoid arthritis (ra), was found to be a potent, noncytotoxic inhibitor of igg-rf immune complex-induced lysosomal enzyme release (ler) from human leukocytes. at a concentration of 1 microg au/ml (5 microm), auranofin produced a marked reduction in beta-glucuronidase (100%), acid phosphatase (88%), and lysozyme (72%) release. in contrast, gold sodium thiosulfate (gst, an injectable gold compound) had no inhibitory activ ... | 1977 | 104928 |