| [changes in the degree of sensitivity to antibiotics of shigella isolated from patients with dysentery in a city infectious disease hospital over the past 8 years]. | changes in sensitivity of shigella and in particular shigella flexneri isolated from dysentery patients in a city infection hospital within 8 years i.e. from 1977 to 1985 were followed. it was shown that the changes were to the greater extent connected with preferable use of certain antibiotics in the hospital. | 1988 | 3288150 |
| effects of marine mammal parasites on human health. | | 1987 | 3294653 |
| an accessory protein identical to mouse egasyn is complexed with rat microsomal beta-glucuronidase and is identical to rat esterase-3. | we report biochemical, immunological, and genetic studies which demonstrate that an accessory protein with the essential features of mouse egasyn is complexed with and stabilizes a portion of beta-glucuronidase in microsomes of rat liver. the accessory protein exists as a complex with beta-glucuronidase since it coprecipitates with beta-glucuronidase after treatment of extracts with a specific beta-glucuronidase antibody. the two proteins are associated by noncovalent bonds since they are easily ... | 1987 | 3294829 |
| epinephrine, glucose, and lactate infusion in exercising adrenodemedullated rats. | the purpose of this study was to determine the metabolic function of the marked increase in plasma epinephrine which occurs in fasted rats during treadmill exercise. fasted adrenodemedullated (adm) and sham-operated (sham) rats were run on a rodent treadmill (21 m/min, 15% grade) for 30 min or until exhaustion. adm rats were infused with saline, epinephrine, glucose, or lactate during the exercise bouts. adm saline-infused rats showed markedly reduced endurance, hypoglycemia, elevated plasma ins ... | 1987 | 3298192 |
| clinical presentation of shigellosis during the 1984 epidemic of bacillary dysentery in west bengal. | | 1987 | 3301795 |
| [a reservoir of shigella of avian origin: herons and birds of prey of the zoological garden in tananarive]. | the authors record the bacteriological characters of four shigella strains: s. dysenteriae 2 and s. boydii 9, respectively isolated in a bird-of-prey and in three herons, kept in the zoological garden in antananarivo. the significance of this malgasian avian reservoir of shigella is discussed. | 1987 | 3304678 |
| a new chromogenic test for the detection of urokinase in the genus shigella. | a simple test for detection of urokinase in shigella is described. the test is performed by suspending a loopful of bacteria in 100 microliters of a buffered 1mm solution of benzoyl-beta-alanyl glycyl-arginyl-4-nitroanilide acetate (chromozym u). enzymatic activity is revealed by formation of a yellow colour after 24 h of incubation at 37 degrees c. the test is able to differentiate serotypes of shigella dysenteriae, shigella flexneri, shigella boydii. the results suggest the possibility of incl ... | 1987 | 3306294 |
| expression of campylobacter jejuni invasiveness in cell cultures coinfected with other bacteria. | enteroinvasive salmonella, shigella, and escherichia coli strains were found to exert an effect which rendered campylobacter jejuni capable of intracellular localization in epithelial cells in vitro. when monolayers of hep-2 or a-549 cells were challenged with pure cultures of c. jejuni or campylobacter coli, none of the eight strains tested invaded the cells. in contrast, four of these strains were able to localize intracellularly when the cells were challenged with a mixture of campylobacters ... | 1987 | 3312015 |
| bactericidal activities of selected organic n-halamines. | the bactericidal efficacies of three organic n,n'-dihalamine disinfectants in the class of compounds termed imidazolidinones were determined for combinations of ph, temperature, and water quality treatments by using staphylococcus aureus and shigella boydii as test organisms. the compound 1,3-dibromo-4,4,5,5-tetramethyl-2-imidazolidinone was found to be the most rapidly acting bactericide, especially under halogen-demand-free conditions. the mixed n,n'-dihalamine 1-bromo-3-chloro-4,4,5,5-tetrame ... | 1987 | 3314705 |
| shigella bacteremia in adults. a report of five cases and review of the literature. | shigella bacteremia is rare, occurring mainly in children. we describe five adult patients with shigella bacteremia and review data on 22 cases reported in the english-language medical literature. eighteen (67%) of 27 patients had either an underlying condition or were aged older than 65 years. most patients had clinical signs of acute febrile gastroenteritis. however, in six patients, the organism was not isolated from stool. species isolated from blood included shigella flexneri in 11 patients ... | 1987 | 3314766 |
| [medico-genetic studies of human provisional organs]. | | 1987 | 3318529 |
| novel oral vaccines: the effectiveness of cloned gene products on inducing secretory immune responses. | | 1987 | 3321939 |
| differential clinical features and stool findings in shigellosis and amoebic dysentery. | to obtain information that could assist the clinician to differentiate between shigellosis and amoebic dysentery, we compared clinical features and stool findings in 58 adult male patients in bangladesh. mean values indicated that patients with invasive amoebiasis were older and had a longer prehospital illness, a lower body weight, less frequent fever, a lower haematocrit and a higher white blood cell count than patients with shigellosis. the mean number of faecal leucocytes per mm3 was signifi ... | 1987 | 3328339 |
| [hoof diseases as a result of stall floor defects]. | the pig's hoof is characterized by sudden changes between hard and soft horn and a high growth rate of the horn wall. these facts contribute to the high incidence of hoof alterations, which is seen in various inadequate floors. hoof alterations are only painful in cases, where the corium is irritated. some hoof alterations are described, the question of poor footing is discussed. the author provides recommendations regarding the recognition of inadequate barn floors and their improvement. stable ... | 1988 | 3368898 |
| trichosanthin, alpha-momorcharin and beta-momorcharin: identity of abortifacient and ribosome-inactivating proteins. | the abortifacient proteins trichosanthin, alpha-momorcharin and beta-momorcharin at nm concentrations inhibit cell-free protein synthesis. the momorcharins and the ribosome-inactivating proteins isolated from momordica charantia seeds cross-react with the respective antisera. the ribosome-inactivating proteins saporins, pokeweed antiviral protein (pap) and, to a lesser extent, gelonin have abortifacient activity on pregnant mice. | 1988 | 3372132 |
| transient increase of cytosolic free calcium in cultured human vascular endothelial cells by platelet-activating factor. | the effect of platelet-activating factor (paf-acether) on cytosolic free calcium, [ca2+]i, in adherent human vascular endothelial cells in culture was directly determined using a new fluorescent calcium indicator, fura-2. it was found that paf-acether but not lyso paf-acether induced a rapid and transient increase in [ca2+]i in endothelial cells. restimulation with paf-acether after the first challenge did not cause further response, while the cells were able to respond to thrombin. in the absen ... | 1988 | 3408504 |
| liver cell lines. | | 1987 | 3431441 |
| serological investigations for the cause of diarrhoea among patients and personnel in the minna and abeokuta hospitals/nigeria. | 188 blood samples were investigated for antibodies against bacteria causing diarrhoea in two hospitals in minna and abeokuta in nigeria. antibodies were found against entamoeba histolytica, yersinia enterocolitica, campylobacter jejuni, salmonella typhi, salmonella paratyphi c, shigella dysenteriae, shigella sonnei, shigella boydii, shigella flexneri and rotavirus. | 1987 | 3443752 |
| residual nitrobenzylthioinosine-resistant nucleoside transport in a transport mutant (ae1) of s49 murine t-lymphoma cells. | the uptake of various nucleosides by s49 mouse t-lymphoma cells and that by a single-step nucleoside transport-defective mutant thereof (ae1) were compared. residual nucleoside entry into ae1 cells occurred via two routes, nonmediated permeation and saturable, non-concentrative transport with broad substrate specificity and a michaelis-menten constant approximating that for thymidine transport in wild-type cells. however, in contrast to nucleoside transport in wild-type cells, residual nucleosid ... | 1987 | 3494190 |
| dexamethasone pre-treatment is antipyretic toward polyinosinic: polycytidylic acid, lipopolysaccharide and interleukin 1/endogenous pyrogen. | the effect of intravenously injected dexamethasone on the febrile response of rabbits to polyinosinic: polycytidylic acid (poly i:c), lipopolysaccharide (lps) and interleukin 1/endogenous pyrogen (il1/e.p.) was studied. dexamethasone (1 mg/kg) attenuated the febrile response to poly i:c (5 micrograms/kg) but only if administered between 0.5 to 2 h before poly i:c. if it was given after poly i:c this resulted in a potentiation of the fever. antagonism of the febrile response to poly i:c by dexame ... | 1987 | 3495738 |
| [development of the classification of bacteria in the genus shigella]. | | 1986 | 3518304 |
| the relation between production of cytotoxin and clinical features in shigellosis. | the relation between in vitro production of hela cell cytotoxin by strains of shigella and clinical symptomatology was determined for 35 travelers from the united states who developed shigellosis in guadalajara, mexico. there were 25 patients with shigella sonnei, eight with shigella flexneri, one with shigella boydii, and one with shigella dysenteriae. these strains were evaluated for in vitro production of cytotoxin. the amount of cytotoxin did not correlate with the number of stools passed, t ... | 1986 | 3519788 |
| [conjugative r-plasmids simultaneously belonging to the 2 incompatibility groups inc i zeta and inc b]. | five plasmids detected in the clinical strains of shigella were studied. the plasmids had similar phenotypes of antibiotic resistance and allotted streptomycin and tetracycline resistance to the host cell. none of them allotted the bacterial cells with sensitivity to phages specific for the inc groups f, n, p and i. the molecular weights of the plasmids ranged from 47 to 50 md. the studies on the incompatibility showed that pkmr 227, pkmr 228-1, pkmr 231, pkmr 242-1 and pkmr 245 plasmids simulta ... | 1986 | 3521469 |
| comparison of dna probes and the sereny test for identification of invasive shigella and escherichia coli strains. | forty-two shigella and 29 escherichia coli strains were screened for invasiveness in the sereny test and for hybridization with two recently described dna probes for the invasiveness plasmid. both probes produced identical results. all sereny-positive strains hybridized with both dna probes. three sereny-negative strains also hybridized with the probes, suggesting that there are strains containing the invasiveness plasmid that are not pathogenic in animal models. | 1986 | 3531233 |
| production of shiga toxin and other cytotoxins by serogroups of shigella. | we measured the cytotoxic activity of 119 strains of shigella by using a quantitative [3h]thymidine-labeled hela cell assay. we assayed 13 strains of shigella dysenteriae 1; 18 strains of s. dysenteriae types 2 and 3; and 88 strains of shigella sonnei, shigella flexneri, and shigella boydii. strains of s. dysenteriae 1 demonstrated high levels of cytotoxicity (geometric mean, 10(5.04) cd50/mg of protein; range, 10(3.95)-10(6.10). cytotoxic activities of the non-type 1 strains of s. dysenteriae a ... | 1986 | 3537154 |
| shigella from ovine faeces. | | 1986 | 3541356 |
| isotope exchange at equilibrium studies with rat muscle adenylosuccinate synthetase. | the kinetic mechanism of rat muscle adenylosuccinate synthetase was studied by determining the rates of isotope exchange at equilibrium. a random sequential binding mechanism was indicated for both the forward and reverse reactions. aspartate, adenylosuccinate, gdp, and pi were determined to bind in rapid equilibrium. gtp exchanges with both gdp and pi at the same rate, which is similar to the exchange rate of imp with adenylosuccinate. aspartate exchanges with adenylosuccinate at a higher rate ... | 1986 | 3542024 |
| [bacteriological study of shigellosis in the lake kivu area (central africa). developments in the last 15 years (1968-1983)]. | 1913 shigella strains were isolated from 1968 to 1983 in lake kivu area (central africa). distribution and evolution of serotypes, biotypes and antibiotypes were studied. the majority of serotypes and biotypes were stable. however, few of these strains showed variations, among them shigella dysenteriae serotype 1, causing epidemic dysenteriae since 1981. epidemiologic survey of shigellosis in kivu seems to be rather underdeveloped (4 bacteriology laboratories for an area of 10 million inhabitant ... | 1986 | 3542256 |
| convulsions in childhood shigellosis. clinical and laboratory features in 153 children. | we studied 153 children who experienced convulsions associated with shigellosis. the male-female ratio was 1.2:1.0. thirty-six children had a previous history of febrile convulsions, and 31 children had a family history of convulsive disorder. most of the children were 0.5 to 3 years of age, although 49 (32%) were older than 3 years of age and 20 (13.1%) were older than 5 years of age. all children were febrile; in 75% of the children, the temperature was over 39 degrees c. the majority of the c ... | 1987 | 3544808 |
| voluntary hyperventilation changes recruitment order of parasternal intercostal motor units. | the order of recruitment of single-motor units in parasternal intercostal muscles during inspiration was studied in normal human subjects during quiet breathing and voluntary hyperventilation. electromyograms were recorded from the second and third intercostal spaces by means of bipolar fine wire electrodes. flow at the mouth, volume, end-expired co2, and rib cage and abdominal anterior-posterior diameters were monitored. single-motor units were identified using criteria of amplitude and shape, ... | 1987 | 3558179 |
| [proliferative activity of experimental brain tumors]. | the method of autoradiography was used to study the parameters of the cell cycle and the intensity of proliferative processes in three transplantable rat brain tumors differing in the duration of the latent period and sensitivity to chemotherapy. the tumors were found to be similar in the duration of the cell cycle and its phases, the mean values of the label index and growth fraction, and were characterized by the irregularity of the proliferative processes within the tumor; the label index was ... | 1987 | 3564792 |
| fatal infectious mononucleosis and virus-associated hemophagocytic syndrome. | a detailed clinicopathologic analysis of 52 cases of fatal infectious mononucleosis was performed. fever, rash, generalized lymphadenopathy, hepatosplenomegaly, and blood cytopenias were the characteristic findings. epstein-barr virus infection was documented in 44 of the 52 patients. a triphasic process evolved in the blood and bone marrow of 43 patients. early, the leukocyte count was elevated due to numerous atypical lymphoid cells, and the marrow was hyperplastic. later, severe pancytopenia ... | 1987 | 3579509 |
| storage conditions and stability of thyrotropin and thyroid hormones on filter paper. | we evaluated the effects of temperature and humidity on thyroid hormones (t4, t3) and thyrotropin (tsh) measured in blood spots dried on filter paper. rias for t4 and t3 blood spots were optimized to measure these analytes over the neonatal and euthyroid adult reference intervals. sensitivities of the t3 and t4 assays were 0.5 and 10 nmol/l, respectively. a blood-spot immunoradiometric assay for tsh involving magnetizable particles was developed with a sensitivity of 6 milli-int. units/l. contro ... | 1987 | 3594835 |
| storage conditions and stability of thyrotropin and thyroid hormones on filter paper. | we evaluated the effects of temperature and humidity on thyroid hormones (t4, t3) and thyrotropin (tsh) measured in blood spots dried on filter paper. rias for t4 and t3 blood spots were optimized to measure these analytes over the neonatal and euthyroid adult reference intervals. sensitivities of the t3 and t4 assays were 0.5 and 10 nmol/l, respectively. a blood-spot immunoradiometric assay for tsh involving magnetizable particles was developed with a sensitivity of 6 milli-int. units/l. contro ... | 1987 | 3594835 |
| changes in hemodynamics and myocardial contractility during chronic sodium depletion in conscious dogs. | chronic sodium depletion has been reported to decrease ejection fraction in anesthetized dogs. we tested the hypothesis that this reduction in cardiac performance is due to either hemodynamic or humoral factors. seven mongrel dogs were fed a low sodium diet (less than 2 meq na+ per day) for 5 weeks. echocardiographic and radionuclide techniques were used to monitor cardiac function. there was a gradual but significant (p less than 0.01) decrease in ejection fraction from 61 +/- 7% (sd) at baseli ... | 1987 | 3596785 |
| effect of organic vehicles on the pharmacokinetics of aminophylline administered intravenously to goats. | aminophylline dissolved in water, propylene glycol, or dimethyl sulfoxide was administered intravenously to goats in a randomized cross-over experiment. model-dependent and model-independent pharmacokinetic parameters for theophylline were compared on the basis of the solvent used in the dosage form administered. no difference was found in any pharmacokinetic parameter. thus, we found no evidence for the possibility that the organic solvents studied would confound pharmacokinetic investigations ... | 1987 | 3612942 |
| pentapeptide nuclear localization signal in adenovirus e1a. | the adenovirus e1a gene products are nuclear proteins important in transcriptional control of viral functions during infection. by producing normal e1a proteins and derivatives of e1a in bacteria and microinjecting these proteins into cultured cells, we were able to examine their ability to localize to the nucleus. we showed that a short peptide sequence at the carboxyl terminus of e1a is necessary for the rapid (30-min) nuclear localization of that protein. additionally, we showed that just the ... | 1987 | 3614197 |
| link protein interactions with hyaluronate and proteoglycans. characterization of two distinct domains in bovine cartilage link proteins. | hyaluronic acid-binding region and trypsin-link protein were prepared from bovine nasal cartilage proteoglycan complex after trypsin digestion. binary complexes were reformed between trypsin-link protein and hyaluronic acid-binding region or hyaluronate. upon trypsin treatment of these complexes, two fragments deriving from trypsin-link protein were characterized. one of them, of 20 kda, corresponds in fact to a 140-amino acid long fragment and bears the glycosylated site of trypsin-link protein ... | 1987 | 3654611 |
| liposome as an adjuvant for the production of estradiol antibodies. | mice immunized with liposome associated estradiol-bovine serum albumin conjugate (e2-bsa) showed a significantly higher estradiol-specific immune response than did mice injected with the free conjugate. the conjugation of estradiol with bsa is imperative, since injection of liposomes with estradiol in the lipid bilayer was found to be ineffective in inducing an immune response. entrapment of e2-bsa in neutral and positively charged liposomes was found to be a potent mode of immunostimulation, ev ... | 1987 | 3666803 |
| somatotopic organization of motoneurons innervating the pronators, carpal and digital flexors and forepaw muscles in the dog: a retrograde horseradish peroxidase study. | central distribution of motor neurons innervating the individual forearm and forepaw muscle through the median and ulnar nerves was studied in the dog using the retrograde horseradish peroxidase (hrp) method. all hrp-labeled cells were seen ipsilaterally in restricted parts within the dorsolateral (dl) and retrodorsolateral nucleus (rdl) of the ventral horn at levels from the cranial tip of c7 to the cranial third of t2. the results showed that motoneurons situated more cranially supply the more ... | 1986 | 3708348 |
| [fasciculation of the median nerve in adults and in the human fetus]. | | 1986 | 3726653 |
| establishment of passive hemagglutination assay (pha) system for anti-hbc in plasma. | a sensitive and specific assay system for anti-hbc, the passive hemagglutination (pha) method, has been established. the reactivity of pha cells prepared by conjugating purified recombinant hbcag-particles with fixed sheep blood cells (srbc) was highly specific to monoclonal- and polyclonal anti-hbc iggs. the sensitivity of pha method was higher than that of radioimmunoassay (ria). however, uncertainty for the positivity of anti-hbc still remained in plasma with the pha titers lower than 2(5). a ... | 1986 | 3738912 |
| 1,25-dihydroxyvitamin d3 treatment results in increased choline acetyltransferase activity in specific brain nuclei. | to better understand the role of 1,25-dihydroxyvitamin d3 [1,25-(oh)2d3] in brain function, the level of calcium-binding protein (cabp) and the activities of choline acetyltransferase (cat) and monoamine oxidase were measured in discrete brain nuclei of vitamin d-deficient and -replete male rats. the nuclei sampled were those in which receptors for 1,25-(oh)2d3 and/or vitamin d-dependent cabp have been localized. significant elevations in cat activity were found in the arcuatemedian eminence and ... | 1986 | 3753932 |
| [establishment of a spontaneously transformed human fetal lung cell line and its biological characteristics]. | a spontaneously transformed human fetal lung cell line (hflt) was derived from a human fetal lung diploid fibroblast cell line (2bs) by continuous culture. the biological characteristics of this cell line were studied and compared with those of 2bs cells. accompanying the morphological alteration, the growth rate of the transformed cell was accelerated and the maximum cell density was increased. the anchorage-independent growth was shown by its ability to form colonies in soft agar. the collagen ... | 1986 | 3769747 |
| laser-assisted vasal anastomosis in the rat and man. | in order to study the efficacy of laser-assisted vasal anastomosis (lava), a microscopic carbon dioxide surgical laser (xanar) was utilized in the anastomoses of human vas deferens in vitro and the sprague-dawley rat vas deferens in vivo. the longitudinal tensile and internal hydrostatic pressure strengths of laser-assisted vasal anastomoses were compared to conventional microsurgical suture anastomoses in the human vas deferens. the lava group had a greater mean internal hydrostatic pressure st ... | 1986 | 3773082 |
| [an attempt to create a factorial model of the epizootic process in sheep infected with s. abortus ovis]. | experiments were carried out to build up a factorial model with a group of sheep at different age in an infected region. studied were the aspects of the disease as caused by salmonella abortus ovis alone and in combination with chl. ps. var. ovis. it was found that the factorial model can explain sufficiently well (77.22 per cent) the discussed system--the epizootic process with year-old females and sheep affected with pure and mixed infection. the epizootic process with a mixed infection in the ... | 1986 | 3811206 |
| protein loss of bovine dental enamel during in-vitro subsurface demineralization. | a chemical system based on the dialysis principle was used to study protein loss of dental enamel during demineralization with an acetic-acid buffer solution containing calcium and phosphate, in which the fluoride-ion activity was kept constant. this resulted in a subsurface lesion, with a depth of about 130 microns. after demineralization, protein material was isolated from the demineralization solution. u.v. spectra of the protein showed strong absorbance between 240 and 300 nm. amino-acid com ... | 1985 | 3865639 |
| role of the posterior capsule in the prevention of postoperative bacterial endophthalmitis: experimental primate studies and clinical implications. | the posterior capsule has an important effect on the risk of postoperative bacterial endophthalmitis. in order to investigate whether the posterior capsule inhibited the spread of infection into the vitreous we performed extracapsular cataract extraction in both eyes of 10 primates. in one eye of each primate the posterior capsule was left intact and in the other eye a large posterior capsulectomy was performed. when the anterior chambers were challenged with equivalent inocula of staphylococcus ... | 1985 | 3877524 |
| addition of three new serotypes of shigella boydii to the shigella schema. | no new serotypes have been added to the shigella schema since 1958, although several provisional serotypes have been described. we conducted biochemical and serological studies on three provisional shigella boydii serotypes. four strains of serotype 2710-54 from four widely separated countries, 7 strains of serotype 3615-53 from three different countries, and 31 strains of serotype 1344-78 (e10163) from six different countries were included. reactions of all three serotypes were consistent with ... | 1985 | 3881469 |
| plaque formation by virulent shigella flexneri. | an in vitro tissue culture plaque assay was developed to investigate the intracellular replication and intercellular spread of virulent shigellae. shigella plaques were formed in hela cell monolayers in the presence of an agarose overlay containing tissue culture medium and gentamicin, which eliminated extracellular bacterial growth. microscopically, the plaques were characterized by a central area of dead host cells surrounded by cells infected with shigellae. cells further away from the plaque ... | 1985 | 3884506 |
| studies of metabolites in diarrheal stool specimens containing shigella species by frequency-pulsed electron capture gas-liquid chromatography. | eleven diarrheal stool specimens and 10 control stool specimens from cairo, egypt, were studied by frequency-pulsed electron capture gas-liquid chromatography (fpec-glc). four cases involving shigella sonnei, three cases involving shigella boydii, and four cases involving shigella flexneri were studied. the aqueous stools were centrifuged, extracted with organic solvents, and derivatized to form specific electron-capturing derivatives of carboxylic acids, alcohols, hydroxy acids, and amines. ana ... | 1985 | 3886695 |
| [shigella serotypes isolated july-october 1983 and their antibiotic sensitivity]. | twenty four strains of shigella were isolated from the stool of patients who had been admitted to the hospital with the complaint of diarrhea. of these, 17 were found to be sh. flexneri, and 7 sh. boydii. antibiotic susceptibility tests indicated that all of the 24 isolates probably had multiple resistance factors. twenty three of 24 strains were found to be resistant to ampicillin. this may be important from a therapeutic point of view. | 1985 | 3892249 |
| [detection of shigella antigens in the feces of patients with acute intestinal diseases using a coagglutination reaction]. | a total of 113 patients with acute intestinal diseases have been examined with the use of the coagglutination test. 84.95% of the patients showed the presence of different shigella antigens. in patients with bacteriologically confirmed dysentery the corresponding shigella antigens were detected in 96.97% of cases in s. sonnei dysentery, in 90% of cases in s. flexneri dysentery, in 75% of cases in s. newcastle dysentery and in 100% of bases in s. boydii dysentery. in 81.6% of patients with acute ... | 1985 | 3892986 |
| epidemiology of shigella boydii serotype 2, a strain indigenous to spain. | | 1985 | 3899639 |
| shigella septicemia in elderly patients. | | 1985 | 3899990 |
| [3-year study of shigellosis epidemic in rwanda, central africa. problems of public health and bacteriological aspects]. | since 1979, the lakes region (kivu in zaïre, western uganda, rwanda, burundi) has been stricken by a bacillary dysentery epidemic at s. dysenteriae type 1. supposed to be extinct since the 1950s., this bacillus has revealed a very noticeable virulence as well by the number of registered cases (524/100.000 in 1983 at ruhengeri-rwanda) as its fast break through. demographic density (from 400 to 600/km2) has played an important role and has facilitated the transition toward epidemicity. systematic ... | 1985 | 3906345 |
| determination of nanogram quantities of vanadium in biological material by isotope dilution thermal ionization mass spectrometry with ion counting detection. | | 1985 | 3907412 |
| n-methyl-l-glutamate synthase. | | 1985 | 3911004 |
| mechanism of sbcb-suppression of the recbc-deficiency in postreplication repair in uv-irradiated escherichia coli k-12. | the mechanism by which an sbcb mutation suppresses the deficiency in postreplication repair shown by recb recc mutants of escherichia coli was studied. the presence of an sbcb mutation in uvra recb recc cells increased their resistance to uv radiation. this enhanced resistance was not due to a suppression of the minor deficiency in the repair of dna daughter-strand gaps or to an inhibition of the production of dna double-strand breaks in uv-irradiated uvra recb recc cells; rather, the presence o ... | 1985 | 3911022 |
| photochemical modifications of lac repressor: effect of effectors binding on tryptophan photooxidation. | | 1985 | 3911222 |
| [significance of isolating shigella under epidemiological circumstances]. | | 1985 | 3911318 |
| bactericidal properties of a new water disinfectant. | the n-chloramine compound 3-chloro-4,4-dimethyl-2-oxazolidinone (agent i) has been compared with calcium hypochlorite as to its efficacy as a bactericide for the treatment of water. the study included concentration, contact time, ph, temperature, and water quality as controlled variables. the species of bacteria tested were staphylococcus aureus, pseudomonas aeruginosa, and shigella boydii. in general, for highly pure, demand-free water, calcium hypochlorite was the more rapid disinfectant at a ... | 1985 | 3922300 |
| studies on microsomal azoreduction. n,n-dimethyl-4-aminoazobenzene (dab) and its derivatives. | the azoreduction of n,n-dimethyl-4-aminoazobenzene (dab) and n-methyl-4-amino-azobenzene (mab) by rat liver microsomes was investigated. it was shown that measurement of azoreduction of dab and structurally related azo dyes by the conventional method of substrate disappearance required an anaerobic environment since n-demethylated and ring-hydroxylated metabolites formed aerobically interfered with the assay system, producing quantitatively inaccurate results. oxygen partially, but not totally, ... | 1985 | 3929790 |
| identification of 5-acetamido-3,5,7,9-tetradeoxy-7-[(r)-3-hydroxybutyramido]-l- glycero-l-manno-nonulosonic acid as a component of bacterial polysaccharides. | | 1985 | 3933831 |
| initiation and promotion in young and old animals. implications for human tumour formation. | the significance of ageing in experimental skin carcinogenesis and on the manifestation of tumour formation in man was studied. initiation with the carcinogenic hydrocarbon 7,12-dimethylbenz [a]anthracene and promotion with croton oil in mouse skin showed that tumour formation was unchanged when promotion was delayed 3, 10, 23 or 43 weeks in comparison with that in untreated animals of the same age. the sensitivity to carcinogen treatment of animals over 71 weeks of age was less than that of ani ... | 1985 | 3938448 |
| on dying more than one death. | death (with a capital d) can best be understood as a series of distinct but related deaths. for example, a pregnant woman was found to be brain-dead but her vital functions were artificially sustained for nine weeks until her fetus could be delivered, after which the machines were removed and she died a second, conceptually distinct death. this procedure is probably justifiable, but any legislation or policy regarding such cases should be flexible and should require consent. | 1986 | 3957650 |
| structural identification of platelet activating factor in psoriatic scale. | platelet activating factor was isolated from the lesional scale of psoriatic patients using the method described by bligh and dyer (8). the extract was subjected to thin layer chromatography, and the region of the plate co-migrating with platelet activating factor removed. a portion of each sample was assayed for aggregating activity using washed guinea-pig platelets and the remainder treated with phospholipase c, derivatised, and subjected to reversed phase high performance liquid chromatograph ... | 1985 | 3970690 |
| spatial contrast sensitivity deficits in monkeys produced by optically induced anisometropia. | an anisometropia was simulated in infant rhesus monkeys by securing a high-powered minus lens (-10 d) in front of one eye. the anisometropia rearing procedure was initiated at 30 days of age and was continued for durations of 30, 60, or 90 days. behavioral measurements of spatial contrast sensitivity obtained when the animals were 9 months of age indicated that the monkeys treated for 30 days had equal or nearly equal contrast sensitivities and cut-off spatial frequencies in the two eyes. the 30 ... | 1985 | 3972513 |
| noninvasive measurement of pressure/volume characteristics in human limb veins by electrical admittance plethysmography. | | 1985 | 3974317 |
| [persistent chlamydia infection in cell culture]. | | 1985 | 3993192 |
| [mechanism of the anti-arrhythmic action of phosphocreatine in acute myocardial ischemia]. | the association between phosphocreatine's antifibrillatory action and its effect on the excitement propagation processes in the ischemic area was investigated under acute coronary arterial occlusion in dogs. ischemia considerably reduced the amplitude, and increased the duration and time of onset, in local electrograms, and provoked cardiac fibrillation at the time of occlusion or during the recovery of coronary flow. a single intravenous injection of 300 mg/kg phosphocreatine eliminated cardiac ... | 1985 | 4021280 |
| [ultrastructural aspects of the wound healing process of the skin of albino rats]. | | 1985 | 4089424 |
| effects of l-tryptophan (a natural sedative) on human sleep. | | 1970 | 4097755 |
| structure of the corneal stroma. | | 1970 | 4099087 |
| ipsilateral afferents to the commissural zone of the fascia dentata, demonstrated in decommissurated rats by silver impregnation. | | 1971 | 4106860 |
| resistance of shigellae to ampicillin and other antibiotics. its clinical and epidemiological implications. | | 1972 | 4113693 |
| biochemical basis of the immunogenicity of the common enterobacterial antigen. | of the numerous members of the family enterobacteriaceae only a few strains, notably escherichia coli o14 and r mutants of the e. coli r1-core type, engender antibodies against the common enterobacterial antigen (ca) following immunization of rabbits with heated suspensions or culture supernatants; other members produce nonimmunogenic ca of identical serological specificity. the biochemical basis of the immunogenic properties of ca of the former strains was investigated by determining the relati ... | 1972 | 4117798 |
| immunochemical studies on shigella boydii lipopolysaccharides. | | 1973 | 4123723 |
| histochemical evidence for lipoidal material in secretory granules of rat salivary glands. | | 1973 | 4126259 |
| [immunological investigations on e. coli strains related to shigellae]. | | 1972 | 4145104 |
| sources of leukocytic endogenous mediator in the rat. | | 1973 | 4148803 |
| the purification of portuguese man-of-war nematocyst toxins by gel diffusion. | | 1973 | 4150989 |
| [blood level of some hormones and the activity of blood serum cholinesterase in animals with experimental diseases of the liver]. | | 1969 | 4187690 |
| [radioprotective effect of mexamine on oral administration to monkeys]. | | 1973 | 4202792 |
| bacterial culture longevity: control by inorganic phosphate and temperature. | death of cells in cultures of six species of gram-negative bacteria was accelerated by incorporation in the medium of 10-fold more inorganic phosphate than was needed for growth. death induced by inorganic phosphate was independent of the carbohydrate employed and was enhanced by warm temperatures. | 1974 | 4203788 |
| [adsorptionless production of highly specific antibodies for the agglutination of certain serotypes of shigella]. | | 1973 | 4208008 |
| characteristics of prd1, a plasmid-dependent broad host range dna bacteriophage. | several distinctive properties of prd1, an icosahedral plasmid-dependent phage, are described. the drug-resistance plasmid-dependent host range of prd1 extends beyond the p incompatibility group and includes gram-negative bacteria containing plasmids of incompatibility groups n and w. prd1 phage will infect pseudomonads and enterobacteriaceae containing either a p or w incompatibility group plasmid. prd1 adsorbs to the cell wall of r(+) bacteria and thus its infectivity indicates cell wall alter ... | 1974 | 4211861 |
| the effect of cortisone on s35-uptake by the submaxillary salivary glands in rats. | | 1967 | 4225590 |
| the response of the pituitary-adrenal system to a stressful stimulus: the effect of conditioning and pentobarbitone treatment. | | 1965 | 4284301 |
| a trypsin technic for the preparation of isolated rat anterior pituitary cells. | | 1970 | 4313145 |
| [changes of hepatic glycogen, lactic acid, glucose-6-phosphatase activity and succinate dehydrogenase in the sourse of tumor development under the influence of b thymus extract]. | | 1973 | 4350046 |
| [changes of hepatic glycogen, lactic acid, glucose-6-phosphatase activity and succinate dehydrogenase in the sourse of tumor development under the influence of b thymus extract]. | | 1973 | 4350046 |
| further characterization of a specific p-nitrophenylphosphatase from baker's yeast. | | 1973 | 4357666 |
| an assessment of some molecular parameters of mevalonate kinase from plant and animal sources. | | 1973 | 4361551 |
| [glucocorticoid cytoreceptors in normal and tumorous rat liver tissue]. | | 1974 | 4375349 |
| [shigella infections in the ivory coast (microbiological and epidemiological study]. | | 1974 | 4376317 |
| production of interferon-like inhibitor in chickens after secondary induction by bacteria and virus. | | 1968 | 4385157 |
| in vivo induction of an interferon-like inhibitor by kanamycin. | | 1968 | 4385158 |
| effect of intraaortic balloon counterpulsation (iabcp) in experimental myocardial injury following acute coronary occlusion. | | 1974 | 4413063 |
| regeneration of the smooth-muscle cells, a structural basis for restoration of the slow-potential rhythm in the distal part of the stomach after transection. | | 1974 | 4449086 |